Detailed information for compound 869784

Basic information

Technical information
  • TDR Targets ID: 869784
  • Name: N-(3-bromophenyl)-2-ethyl-2,3-dihydro-1,4-ben zoxazine-4-carboxamide
  • MW: 361.233 | Formula: C17H17BrN2O2
  • H donors: 1 H acceptors: 1 LogP: 4.06 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC1Oc2ccccc2N(C1)C(=O)Nc1cccc(c1)Br
  • InChi: 1S/C17H17BrN2O2/c1-2-14-11-20(15-8-3-4-9-16(15)22-14)17(21)19-13-7-5-6-12(18)10-13/h3-10,14H,2,11H2,1H3,(H,19,21)
  • InChiKey: KNHGRHSRMWKZFD-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0029 0.0041 0.0041
Echinococcus granulosus slit 2 protein 0.0477 0.1799 0.1793
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0072
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0236 0.0854 0.1151
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0099 0.0313 0.0565
Onchocerca volvulus Neurogenic locus notch homolog 0.0477 0.18 0.1794
Brugia malayi GCC2 and GCC3 family protein 0.0477 0.1799 0.1799
Loa Loa (eye worm) hypothetical protein 0.2565 1 1
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0043 0.0093 0.0133
Mycobacterium ulcerans carbonic anhydrase 0.1502 0.5826 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0029 0.0041 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.1502 0.5826 1
Schistosoma mansoni notch 0.0477 0.1799 0.1793
Brugia malayi Protein kinase domain containing protein 0.0303 0.1114 0.1114
Entamoeba histolytica protein kinase, putative 0.0303 0.1114 0.2078
Schistosoma mansoni cytochrome c oxidase subunit II 0.0129 0.0433 0.0426
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0096 0.0089
Brugia malayi Calcium binding EGF domain containing protein 0.0477 0.1799 0.1799
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0096 0.0172
Echinococcus granulosus tumor protein p63 0.0704 0.2691 0.2685
Toxoplasma gondii thioredoxin reductase 0.0043 0.0095 0.0166
Loa Loa (eye worm) histone deacetylase 7A 0.0121 0.0399 0.0399
Echinococcus multilocularis voltage dependent calcium channel 0.0043 0.0093 0.0086
Echinococcus granulosus protein jagged 1 0.0477 0.1799 0.1793
Toxoplasma gondii hypothetical protein 0.0038 0.0072 0.0058
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0044 0.0096 0.0089
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0096 0.0096
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0096 0.105
Echinococcus granulosus histone deacetylase 1 0.0236 0.0854 0.0847
Loa Loa (eye worm) hypothetical protein 0.0044 0.0096 0.0096
Echinococcus granulosus histone deacetylase 6 0.0121 0.0399 0.0392
Onchocerca volvulus 0.0477 0.1799 0.1793
Onchocerca volvulus 0.0217 0.0776 0.0769
Schistosoma mansoni hypothetical protein 0.0477 0.1799 0.1793
Toxoplasma gondii histone deacetylase HDAC1 0.0121 0.0399 0.1639
Loa Loa (eye worm) steroid hormone receptor 0.0029 0.0041 0.0041
Mycobacterium ulcerans epoxide hydrolase EphA 0.0173 0.0606 0.0988
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Plasmodium falciparum inorganic anion exchanger, inorganic anion antiporter 0.0035 0.0061 0.0252
Schistosoma mansoni peroxidasin 0.2565 1 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0096 0.0096
Onchocerca volvulus 0.2565 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0029 0.0041 0.0041
Toxoplasma gondii EGF family domain-containing protein 0.0477 0.1799 0.8424
Toxoplasma gondii cytochrome C oxidase subunit IIb, putative 0.0048 0.0113 0.0252
Brugia malayi EGF-like domain containing protein 0.0477 0.1799 0.1799
Mycobacterium tuberculosis Probable oxidoreductase 0.011 0.0356 0.0676
Echinococcus multilocularis serotonin transporter 0.0256 0.0932 0.0926
Loa Loa (eye worm) Notch2 0.0477 0.1799 0.1799
Loa Loa (eye worm) hypothetical protein 0.2565 1 1
Schistosoma mansoni histone deacetylase 1 2 3 0.0091 0.0281 0.0274
Schistosoma mansoni histone deacetylase hda2 0.0091 0.0281 0.0274
Trypanosoma cruzi histone deacetylase, putative 0.0121 0.0399 0.0822
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.011 0.0356 0.0676
Mycobacterium tuberculosis Beta-carbonic anhydrase 0.1032 0.3978 1
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0173 0.0606 0.132
Brugia malayi Doublecortin family protein 0.0021 0.0007 0.0007
Echinococcus multilocularis tumor protein p63 0.0704 0.2691 0.2685
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0043 0.0093 0.0086
Loa Loa (eye worm) hypothetical protein 0.2565 1 1
Mycobacterium tuberculosis Probable serine acetyltransferase CysE (sat) 0.0075 0.0218 0.0322
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0096 0.0089
Mycobacterium ulcerans transmembrane cytochrome C oxidase (subunit II) CtaC 0.0048 0.0113 0.0136
Schistosoma mansoni cellular tumor antigen P53 0.0103 0.033 0.0323
Schistosoma mansoni sodium/chloride dependent transporter 0.0256 0.0932 0.0926
Echinococcus granulosus delta-like protein 1 0.0477 0.1799 0.1793
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0029 0.0041 0.0034
Onchocerca volvulus 0.2565 1 1
Onchocerca volvulus 0.0044 0.0096 0.0089
Echinococcus granulosus neurogenic locus notch protein 0.0477 0.1799 0.1793
Leishmania major carbonic anhydrase family protein, putative 0.1294 0.5007 1
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0035 0.0061 0.0046
Brugia malayi Histone deacetylase 1 0.0236 0.0854 0.0854
Schistosoma mansoni lipoxygenase 0.0125 0.0416 0.041
Loa Loa (eye worm) hypothetical protein 0.1187 0.4589 0.4589
Leishmania major trypanothione reductase 0.0043 0.0095 0.0123
Plasmodium falciparum histone deacetylase 2 0.0121 0.0399 0.185
Trypanosoma brucei histone deacetylase 1 0.0236 0.0854 0.1845
Echinococcus granulosus peroxidasin 0.2565 1 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0041 0.0041
Plasmodium falciparum cytochrome c oxidase subunit 2, putative 0.0048 0.0113 0.0498
Echinococcus granulosus histone deacetylase 0.0121 0.0399 0.0392
Loa Loa (eye worm) hypothetical protein 0.2565 1 1
Echinococcus multilocularis fat cadherin tumor suppressor 0.0477 0.1799 0.1793
Toxoplasma gondii histone deacetylase HDAC4 0.0091 0.0281 0.1066
Loa Loa (eye worm) hypothetical protein 0.2565 1 1
Brugia malayi Animal haem peroxidase family protein 0.2565 1 1
Brugia malayi Cadherin domain containing protein 0.0477 0.1799 0.1799
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0044 0.0096 0.0089
Plasmodium falciparum histone deacetylase 1 0.0236 0.0854 0.3997
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0029 0.0041 0.0041
Trypanosoma brucei trypanothione reductase 0.0043 0.0095 0.0138
Echinococcus multilocularis carbonic anhydrase 0.056 0.2125 0.2119
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Echinococcus multilocularis carbonic anhydrase II 0.1159 0.4477 0.4473
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0303 0.1114 0.1108
Echinococcus multilocularis neurogenic locus notch protein 0.0477 0.1799 0.1793
Echinococcus multilocularis thioredoxin glutathione reductase 0.0043 0.0095 0.0088
Loa Loa (eye worm) hypothetical protein 0.2565 1 1
Trichomonas vaginalis AGC family protein kinase 0.0303 0.1114 0.1615
Plasmodium vivax thioredoxin reductase, putative 0.0043 0.0095 0.1037
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Brugia malayi EGF-like domain containing protein 0.0477 0.1799 0.1799
Loa Loa (eye worm) hypothetical protein 0.2565 1 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.056 0.2125 0.2125
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0041 0.0034
Trypanosoma brucei histone deacetylase 2 0.0091 0.0281 0.0556
Trypanosoma cruzi histone deacetylase, putative 0.0121 0.0399 0.0822
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.056 0.2125 0.2125
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0035 0.0061 0.006
Echinococcus multilocularis mitogen activated protein kinase 14 0.0136 0.0461 0.0454
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0041 0.0041
Brugia malayi Steroid receptor seven-up type 2 0.0029 0.0041 0.0041
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0043 0.0093 0.0093
Trypanosoma brucei Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0035 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0256 0.0932 0.0932
Brugia malayi Animal haem peroxidase family protein 0.2565 1 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0096 0.0089
Brugia malayi hypothetical protein 0.0021 0.0007 0.0007
Trypanosoma brucei histone deacetylase 3 0.0121 0.0399 0.0822
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0029 0.0041 0.0034
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0477 0.1799 0.1793
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0029 0.0041 0.0034
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0099 0.0313 0.0565
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0477 0.1799 0.1799
Loa Loa (eye worm) hypothetical protein 0.0029 0.0041 0.0041
Loa Loa (eye worm) voltage-dependent calcium channel 0.0043 0.0093 0.0093
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0029 0.0041 0.0041
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0096 0.0089
Toxoplasma gondii histone deacetylase HDAC3 0.0236 0.0854 0.3842
Echinococcus multilocularis neurogenic locus protein delta 0.0477 0.1799 0.1793
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0096 0.0172
Schistosoma mansoni histone deacetylase 4 5 0.0121 0.0399 0.0392
Schistosoma mansoni notch 0.0477 0.1799 0.1793
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0029 0.0041 0.0034
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0044 0.0096 0.0089
Echinococcus granulosus carbonic anhydrase 0.056 0.2125 0.2119
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0029 0.0041 0.0034
Onchocerca volvulus Bile acid receptor homolog 0.0029 0.0041 0.0034
Trypanosoma cruzi histone deacetylase 1, putative 0.0236 0.0854 0.1845
Loa Loa (eye worm) calcium channel 0.0043 0.0093 0.0093
Echinococcus granulosus carbonic anhydrase II 0.1159 0.4477 0.4473
Schistosoma mansoni hypothetical protein 0.0477 0.1799 0.1793
Trichomonas vaginalis histone deacetylase, putative 0.0236 0.0854 0.1151
Brugia malayi nuclear hormone receptor 0.0029 0.0041 0.0041
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0096 0.0172
Loa Loa (eye worm) hypothetical protein 0.0029 0.0041 0.0041
Schistosoma mansoni laminin gamma-3 chain 0.0477 0.1799 0.1793
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.056 0.2125 0.2125
Schistosoma mansoni histone deacetylase hda2 0.0127 0.0425 0.0418
Echinococcus multilocularis histone deacetylase 6 0.0121 0.0399 0.0392
Echinococcus granulosus serotonin transporter 0.0256 0.0932 0.0926
Plasmodium vivax histone deacetylase 1, putative 0.0236 0.0854 1
Onchocerca volvulus 0.0072 0.0207 0.02
Onchocerca volvulus Putative sulfate transporter 0.0217 0.0776 0.0769
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.1159 0.4477 0.4477
Loa Loa (eye worm) hypothetical protein 0.2565 1 1
Loa Loa (eye worm) hypothetical protein 0.0236 0.0854 0.0854
Mycobacterium leprae CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) 0.1294 0.5007 1
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Schistosoma mansoni sodium-dependent amino acid transporter 0.0044 0.0096 0.0089
Loa Loa (eye worm) cytochrome P450 family protein 0.0077 0.0228 0.0228
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0303 0.1114 0.1114
Brugia malayi EGF-like domain containing protein 0.0477 0.1799 0.1799
Brugia malayi Calcium binding EGF domain containing protein 0.0477 0.1799 0.1799
Brugia malayi EGF-like domain containing protein 0.0477 0.1799 0.1799
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0256 0.093 0.093
Loa Loa (eye worm) notch protein 0.0477 0.1799 0.1799
Loa Loa (eye worm) hypothetical protein 0.0029 0.0041 0.0041
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0043 0.0093 0.0133
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0029 0.0041 0.0041
Brugia malayi P38 map kinase family protein 2 0.0136 0.0461 0.0461
Toxoplasma gondii histone deacetylase HDAC5 0.0091 0.0281 0.1069
Schistosoma mansoni hypothetical protein 0.0134 0.0449 0.0443
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Mycobacterium ulcerans transferase 0.0072 0.0207 0.0299
Brugia malayi photoreceptor-specific nuclear receptor 0.0029 0.0041 0.0041
Schistosoma mansoni thyroid hormone receptor 0.0163 0.0565 0.0559
Onchocerca volvulus Cytochrome c oxidase subunit 2 homolog 0.0048 0.0113 0.0105
Plasmodium falciparum carbonic anhydrase 0.056 0.2125 1
Echinococcus granulosus neurogenic locus notch protein 4 0.0477 0.1799 0.1793
Brugia malayi histone deacetylase 1 (HD1) 0.0236 0.0854 0.0854
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.0999 0.385 0.3846
Plasmodium vivax histone deacetylase 2, putative 0.0121 0.0399 0.4628
Trichomonas vaginalis AGC family protein kinase 0.0303 0.1114 0.1615
Loa Loa (eye worm) hypothetical protein 0.2565 1 1
Loa Loa (eye worm) histone deacetylase 3 0.0236 0.0854 0.0854
Loa Loa (eye worm) hypothetical protein 0.056 0.2125 0.2125
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0099 0.0313 0.0553
Schistosoma mansoni carbonic anhydrase-related 0.056 0.2125 0.2119
Loa Loa (eye worm) norepinephrine transporter 0.0256 0.0932 0.0932
Echinococcus multilocularis fibropellin Ia 0.0477 0.1799 0.1793
Brugia malayi glutathione reductase 0.0043 0.0095 0.0095
Plasmodium vivax conserved Plasmodium protein, unknown function 0.011 0.0358 0.4144
Brugia malayi ecdysteroid receptor 0.0029 0.0041 0.0041
Mycobacterium leprae PROBABLE TRANSFERASE 0.0072 0.0207 0.0341
Trichomonas vaginalis conserved hypothetical protein 0.1502 0.5826 1
Brugia malayi Cadherin domain containing protein 0.0477 0.1799 0.1799
Onchocerca volvulus Cytochrome c oxidase subunit 2 homolog 0.0048 0.0113 0.0105
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0136 0.0461 0.0859
Echinococcus granulosus nuclear factor of activated T cells 5 0.0078 0.0232 0.0225
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0029 0.0041 0.0034
Brugia malayi EGF-like domain containing protein 0.0477 0.1799 0.1799
Loa Loa (eye worm) hypothetical protein 0.2565 1 1
Treponema pallidum sodium- and chloride- dependent transporter 0.0256 0.0932 0.5
Echinococcus multilocularis histone deacetylase 6 0.0127 0.0425 0.0418
Brugia malayi histone deacetylase 3 (HD3) 0.0236 0.0854 0.0854
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0034 0.0034
Loa Loa (eye worm) cytochrome oxidase subunit 2 0.0029 0.0038 0.0038
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0236 0.0854 0.1151
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0078 0.0232 0.0225
Loa Loa (eye worm) hypothetical protein 0.0029 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0043 0.0093 0.0093
Loa Loa (eye worm) animal heme peroxidase 0.2565 1 1
Onchocerca volvulus Dual oxidase homolog 0.2565 1 1
Onchocerca volvulus 0.0044 0.0096 0.0089
Echinococcus multilocularis neurogenic locus notch protein 4 0.0477 0.1799 0.1793
Brugia malayi Muscle positioning protein 4 0.0477 0.1799 0.1799
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0044 0.0096 1
Echinococcus granulosus neurogenic locus protein delta 0.0477 0.1799 0.1793
Plasmodium falciparum histone deacetylase, putative 0.0121 0.0399 0.185
Wolbachia endosymbiont of Brugia malayi 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 0.0075 0.0218 0.2761
Plasmodium falciparum amino acid transporter, putative 0.0044 0.0096 0.042
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0096 0.0089
Trichomonas vaginalis histone deacetylase, putative 0.0236 0.0854 0.1151
Echinococcus multilocularis neurogenic locus notch protein 0.0477 0.1799 0.1793
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0034 0.0034
Echinococcus granulosus protein jagged 2 0.0477 0.1799 0.1793
Plasmodium vivax cytochrome c oxidase subunit 2, putative 0.0048 0.0113 0.1246
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0096 0.0096
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0029 0.0041 0.0034
Leishmania major histone deacetylase, putative 0.0236 0.0854 0.1648
Echinococcus multilocularis carbonic anhydrase 0.056 0.2125 0.2119
Echinococcus multilocularis histone deacetylase 7 0.0121 0.0399 0.0392
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1159 0.4477 0.4473
Schistosoma mansoni slit 0.0477 0.1799 0.1793
Schistosoma mansoni cytochrome-c oxidase 0.0048 0.0113 0.0105
Plasmodium vivax histone deacetylase, putative 0.0091 0.0281 0.3232
Brugia malayi Animal haem peroxidase family protein 0.2565 1 1
Onchocerca volvulus Cytochrome c oxidase subunit 2 homolog 0.0048 0.0113 0.0105
Trypanosoma cruzi trypanothione reductase, putative 0.0043 0.0095 0.0138
Loa Loa (eye worm) hypothetical protein 0.2565 1 1
Onchocerca volvulus 0.0103 0.033 0.0323
Onchocerca volvulus Slit protein homolog 0.0477 0.1799 0.1793
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0029 0.0041 0.0041
Onchocerca volvulus Cytochrome c oxidase subunit 2 homolog 0.0048 0.0113 0.0105
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0229 0.0825 0.0818
Brugia malayi Histone deacetylase family protein 0.0121 0.0399 0.0399
Brugia malayi Delta serrate ligand family protein 0.0477 0.1799 0.1799
Onchocerca volvulus Peroxidase homolog 0.2565 1 1
Onchocerca volvulus Putative cubilin 0.0477 0.1799 0.1793
Schistosoma mansoni notch 0.0477 0.18 0.1794
Schistosoma mansoni hypothetical protein 0.0477 0.1799 0.1793
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Plasmodium falciparum glutathione reductase 0.0043 0.0095 0.0414
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1159 0.4477 0.4477
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Echinococcus granulosus carbonic anhydrase 0.056 0.2125 0.2119
Schistosoma mansoni hypothetical protein 0.0477 0.1799 0.1793
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.056 0.2125 0.2125
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.1114 0.1108
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.056 0.2125 0.2125
Loa Loa (eye worm) hypothetical protein 0.0044 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0091 0.0281 0.0281
Echinococcus multilocularis ecdysone induced protein 78C 0.0029 0.0041 0.0034
Leishmania major carbonic anhydrase-like protein 0.1159 0.4477 0.8933
Echinococcus granulosus protein jagged 2 0.0477 0.1799 0.1793
Schistosoma mansoni septate junction protein 0.0477 0.1799 0.1793
Onchocerca volvulus 0.0477 0.1799 0.1793
Trypanosoma brucei carbonic anhydrase-like protein 0.1159 0.4477 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0029 0.0041 0.0041
Mycobacterium tuberculosis Probable transmembrane cytochrome C oxidase (subunit II) CtaC 0.0048 0.0113 0.005
Schistosoma mansoni histone deacetylase 0.0236 0.0854 0.0847
Echinococcus granulosus mitogen activated protein kinase 11 0.0136 0.0461 0.0454
Leishmania major hypothetical protein, conserved 0.0043 0.0093 0.0119
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0075 0.0218 0.2761
Echinococcus multilocularis histone deacetylase 1 0.0236 0.0854 0.0847
Onchocerca volvulus 0.0048 0.0113 0.0105
Loa Loa (eye worm) hypothetical protein 0.2565 1 1
Loa Loa (eye worm) hypothetical protein 0.2565 1 1
Schistosoma mansoni notch 0.0477 0.1799 0.1793
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0029 0.0041 0.0034
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Onchocerca volvulus Peroxidasin homolog 0.2565 1 1
Echinococcus granulosus mitogen activated protein kinase 14 0.0136 0.0461 0.0454
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0093 0.0133
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0043 0.0093 0.0086
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Entamoeba histolytica acetyltransferase, putative 0.0075 0.0218 0.0254
Echinococcus granulosus thioredoxin glutathione reductase 0.0043 0.0095 0.0088
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0043 0.0093 0.0086
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0093 0.0133
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0029 0.0041 0.0041
Echinococcus granulosus FTZ F1 alpha 0.0029 0.0041 0.0034
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0043 0.0093 0.0086
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.2565 1 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0029 0.0041 0.0034
Loa Loa (eye worm) hypothetical protein 0.0256 0.0932 0.0932
Onchocerca volvulus Peroxidasin homolog 0.2565 1 1
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Loa Loa (eye worm) hypothetical protein 0.0044 0.0096 0.0096
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0125 0.0416 0.041
Brugia malayi Thioredoxin reductase 0.0043 0.0095 0.0095
Loa Loa (eye worm) animal heme peroxidase 0.2565 1 1
Echinococcus granulosus geminin 0.018 0.0631 0.0624
Loa Loa (eye worm) serotonin transporter b 0.0256 0.0932 0.0932
Loa Loa (eye worm) blistered cuticle protein 3 0.2565 1 1
Onchocerca volvulus Peroxidase homolog 0.2565 1 1
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.025 0.0908 0.2097
Brugia malayi Histone deacetylase family protein 0.0121 0.0399 0.0399
Brugia malayi EGF-like domain containing protein 0.0477 0.1799 0.1799
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0029 0.0041 0.0041
Brugia malayi Cytochrome P450 family protein 0.0028 0.0034 0.0034
Leishmania major histone deacetylase, putative 0.0236 0.0854 0.1648
Entamoeba histolytica carbonic anhydrase, putative 0.1294 0.5007 1
Schistosoma mansoni cell polarity protein 0.0477 0.1799 0.1793
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0029 0.0041 0.0034
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0041 0.0034
Plasmodium vivax sulfate transporter, putative 0.0035 0.0061 0.0631
Schistosoma mansoni microsomal glutathione s-transferase 0.0229 0.0825 0.0818
Schistosoma mansoni carbonic anhydrase-related 0.056 0.2125 0.2119
Loa Loa (eye worm) histone deacetylase 11 0.0091 0.0281 0.0281
Brugia malayi Animal haem peroxidase family protein 0.2565 1 1
Schistosoma mansoni RAR-like nuclear receptor 0.0029 0.0041 0.0034
Echinococcus granulosus histone deacetylase 3 0.0236 0.0854 0.0847
Brugia malayi histone deacetylase 11 0.0091 0.0281 0.0281
Schistosoma mansoni histone deacetylase 4 5 0.0121 0.0399 0.0392
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0035 0.0061 0.006
Loa Loa (eye worm) animal heme peroxidase 0.2565 1 1
Loa Loa (eye worm) histone deacetylase 1 0.0236 0.0854 0.0854
Echinococcus multilocularis histone deacetylase 8 0.0091 0.0281 0.0274
Brugia malayi phosphoinositide-dependent protein kinase I 0.0303 0.1114 0.1114
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0096 0.0089
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0044 0.0096 0.0089
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0256 0.0932 0.0926
Echinococcus granulosus microsomal glutathione S transferase 3 0.0229 0.0825 0.0818
Onchocerca volvulus 0.0477 0.1799 0.1793
Plasmodium vivax glutathione reductase, putative 0.0043 0.0095 0.1037
Schistosoma mansoni thyroid hormone receptor 0.0163 0.0565 0.0559
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0029 0.0041 0.0034
Loa Loa (eye worm) histone deacetylase 0.0121 0.0399 0.0399
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0043 0.0093 0.0086
Echinococcus multilocularis voltage dependent calcium channel 0.0043 0.0093 0.0086
Echinococcus multilocularis protein jagged 1 0.0477 0.1799 0.1793
Echinococcus granulosus histone deacetylase 6 0.0121 0.0399 0.0392
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0029 0.0041 0.0034
Loa Loa (eye worm) hypothetical protein 0.0256 0.0932 0.0932
Trypanosoma cruzi histone deacetylase, putative 0.0121 0.0399 0.0822
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0099 0.0313 0.0565
Echinococcus granulosus fibropellin Ia 0.0477 0.1799 0.1793
Echinococcus granulosus histone deacetylase 8 0.0091 0.0281 0.0274
Trichomonas vaginalis histone deacetylase, putative 0.0236 0.0854 0.1151
Mycobacterium tuberculosis Probable dehydrogenase 0.0099 0.0313 0.0565
Trichomonas vaginalis histone deacetylase, putative 0.0236 0.0854 0.1151
Schistosoma mansoni carbonic anhydrase 0.056 0.2125 0.2119
Giardia lamblia High cysteine protein 0.0477 0.1799 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0043 0.0043
Echinococcus multilocularis histone deacetylase 0.0121 0.0399 0.0392
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0096 0.0089
Schistosoma mansoni histone deacetylase 0.0236 0.0854 0.0847
Echinococcus granulosus carbonic anhydrase 0.056 0.2125 0.2119
Onchocerca volvulus 0.0477 0.1799 0.1793
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Brugia malayi Blistered cuticle protein 3 0.2565 1 1
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0029 0.0041 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0029 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0044 0.0096 0.0096
Toxoplasma gondii histone deacetylase HDAC2 0.0236 0.0854 0.3842
Trichomonas vaginalis histone deacetylase, putative 0.0236 0.0854 0.1151
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0035 0.0061 0.0046
Echinococcus granulosus voltage dependent calcium channel 0.0043 0.0093 0.0086
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0043 0.0093 0.0086
Schistosoma mansoni hypothetical protein 0.018 0.0631 0.0624
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0044 0.0096 0.0096
Mycobacterium ulcerans integral membrane transporter 0.0035 0.0061 0.0046
Schistosoma mansoni steroid hormone receptor ad4bp 0.0029 0.0041 0.0034
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1159 0.4477 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0093 0.0093
Echinococcus granulosus cytochrome c oxidase subunit II 0.0158 0.0545 0.0539
Schistosoma mansoni hypothetical protein 0.056 0.2125 0.2119
Entamoeba histolytica ankyrin, putative 0.0075 0.0218 0.0255
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0029 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0096 0.0089
Mycobacterium tuberculosis Beta-carbonic anhydrase CanB 0.0823 0.3159 0.7893
Echinococcus multilocularis neurogenic locus protein delta 0.0477 0.1799 0.1793
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0096 0.0089
Brugia malayi Cytochrome P450 family protein 0.0077 0.0228 0.0228
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0136 0.0461 0.0961
Echinococcus granulosus histone deacetylase 7 0.0121 0.0399 0.0392
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0044 0.0096 0.0089
Toxoplasma gondii transporter, cation channel family protein 0.0043 0.0093 0.0156
Trichomonas vaginalis histone deacetylase, putative 0.0236 0.0854 0.1151
Echinococcus multilocularis protein jagged 2 0.0477 0.1799 0.1793
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.056 0.2125 0.2125
Echinococcus multilocularis mitogen activated protein kinase 11 0.0136 0.0461 0.0454
Plasmodium falciparum thioredoxin reductase 0.0043 0.0095 0.0414
Echinococcus granulosus neurogenic locus notch protein 0.0477 0.1799 0.1793
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Schistosoma mansoni hypothetical protein 0.018 0.0631 0.0624
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0029 0.0041 0.0041
Loa Loa (eye worm) solute carrier family 6 member 4 0.0256 0.0932 0.0932
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0256 0.0932 0.0932
Echinococcus multilocularis protein jagged 1 0.0477 0.1799 0.1793
Onchocerca volvulus 0.0256 0.0932 0.0926
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0096 0.0089
Echinococcus granulosus histone deacetylase 6 0.0127 0.0425 0.0418
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0029 0.0041 0.0041
Schistosoma mansoni notch 0.0477 0.1799 0.1793
Toxoplasma gondii hypothetical protein 0.0044 0.0096 0.0172
Echinococcus multilocularis mitogen activated protein kinase 14 0.0136 0.0461 0.0454
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0125 0.0416 0.041
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0134 0.0449 0.0443
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1159 0.4477 1
Leishmania major histone deacetylase, putative 0.0121 0.0399 0.0734
Brugia malayi follicle stimulating hormone receptor 0.0256 0.093 0.093
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0041 0.0034
Plasmodium vivax amine transporter, putative 0.0044 0.0096 0.105
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0093 0.0133
Plasmodium vivax histone deacetylase, putative 0.0121 0.0399 0.4628
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0096 0.0089
Loa Loa (eye worm) carbonic anhydrase 3 0.1159 0.4477 0.4477
Onchocerca volvulus 0.0477 0.1799 0.1793
Schistosoma mansoni retinoic acid receptor RXR 0.0029 0.0041 0.0034
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0072
Echinococcus granulosus protein jagged 1 0.0477 0.1799 0.1793
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0303 0.1114 0.1114
Trichomonas vaginalis AGC family protein kinase 0.0303 0.1114 0.1615
Brugia malayi steroid hormone receptor 0.0029 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0037 0.0069 0.0069
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0029 0.0041 0.0041
Schistosoma mansoni carbonic anhydrase 0.1294 0.5007 0.5004
Brugia malayi hypothetical protein 0.0021 0.0007 0.0007
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0043 0.0095 0.0005
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0096 0.0096
Echinococcus multilocularis thyroid hormone receptor alpha 0.0163 0.0565 0.0559
Onchocerca volvulus 0.0044 0.0096 0.0089
Echinococcus multilocularis geminin 0.018 0.0631 0.0624
Mycobacterium tuberculosis Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) 0.0721 0.2756 0.6855
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0096 0.0089
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0096 0.0089
Trypanosoma brucei histone deacetylase, putative 0.0121 0.0399 0.0822
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0029 0.0041 0.0041
Loa Loa (eye worm) glutathione reductase 0.0043 0.0095 0.0095
Trypanosoma cruzi histone deacetylase, putative 0.0091 0.0281 0.0556
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0096 0.0089
Loa Loa (eye worm) hypothetical protein 0.0103 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.0044 0.0096 0.0096
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0096 0.0089
Echinococcus granulosus notch 0.0477 0.1799 0.1793
Schistosoma mansoni carbonic anhydrase-related 0.056 0.2125 0.2119
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0303 0.1114 0.1108
Schistosoma mansoni peroxidasin 0.2565 1 1
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Schistosoma mansoni coup transcription factor 0.0029 0.0041 0.0034
Loa Loa (eye worm) thioredoxin reductase 0.0043 0.0095 0.0095
Mycobacterium ulcerans hypothetical protein 0.0043 0.0093 0.0102
Echinococcus granulosus dynactin 5 p25 0.0075 0.0218 0.0211
Mycobacterium tuberculosis Probable reductase 0.0099 0.0313 0.0565
Brugia malayi Cytochrome P450 family protein 0.0028 0.0034 0.0034
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0477 0.1799 0.1793
Echinococcus multilocularis histone deacetylase 3 0.0236 0.0854 0.0847
Brugia malayi Calcium binding EGF domain containing protein 0.0477 0.1799 0.1799
Schistosoma mansoni voltage-gated cation channel 0.0043 0.0093 0.0086
Echinococcus multilocularis mitogen activated protein kinase 11 0.0136 0.0461 0.0454
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1159 0.4477 0.4473
Brugia malayi Animal haem peroxidase family protein 0.2565 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0029 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0477 0.1799 0.1793
Onchocerca volvulus Protein ultraspiracle homolog 0.0029 0.0041 0.0034
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0136 0.0461 0.0961
Schistosoma mansoni sodium/chloride dependent transporter 0.0047 0.0109 0.0102
Leishmania major histone deacetylase, putative 0.0121 0.0399 0.0734
Onchocerca volvulus Chorion peroxidase homolog 0.2565 1 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0029 0.0041 0.0041
Toxoplasma gondii MAPEG family protein 0.0229 0.0825 0.3701
Loa Loa (eye worm) animal heme peroxidase 0.2565 1 1
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0043 0.0093 0.0086
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0034 0.0034
Echinococcus granulosus neural cadherin 0.0477 0.1799 0.1793
Onchocerca volvulus 0.2565 1 1
Echinococcus granulosus ecdysone induced protein 78C 0.0029 0.0041 0.0034
Trypanosoma cruzi histone deacetylase 1, putative 0.0236 0.0854 0.1845
Entamoeba histolytica histone deacetylase, putative 0.0236 0.0854 0.1547
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0041 0.0034
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0043 0.0093 0.0086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0044 0.0096 0.0096
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0041 0.0034
Wolbachia endosymbiont of Brugia malayi cytochrome c oxidase, subunit 2 0.0158 0.0545 1
Brugia malayi nuclear receptor NHR-88 0.0029 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0029 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Toxoplasma gondii hypothetical protein 0.056 0.2125 1
Onchocerca volvulus 0.0029 0.0041 0.0034
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0029 0.0041 0.0034
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0136 0.0461 0.0961
Echinococcus multilocularis peroxidasin 0.2565 1 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0029 0.0041 0.0034
Echinococcus multilocularis histone deacetylase 6 0.0121 0.0399 0.0392
Brugia malayi hypothetical protein 0.0044 0.0096 0.0096
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0043 0.0093 0.0086
Brugia malayi Putative carbonic anhydrase 5 precursor 0.1159 0.4477 0.4477
Mycobacterium leprae Probable transmembrane transport protein 0.025 0.0908 0.1751
Loa Loa (eye worm) hypothetical protein 0.0029 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0477 0.1799 0.1793
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0096 0.0096
Brugia malayi Peroxidasin 0.2565 1 1
Toxoplasma gondii hypothetical protein 0.0044 0.0096 0.0172
Onchocerca volvulus Histone deacetylase 10 homolog 0.0091 0.0281 0.0274
Echinococcus multilocularis carbonic anhydrase 0.056 0.2125 0.2119
Mycobacterium ulcerans carbonic anhydrase 0.1294 0.5007 0.8587
Echinococcus granulosus voltage dependent calcium channel 0.0043 0.0093 0.0086
Echinococcus multilocularis FTZ F1 alpha 0.0029 0.0041 0.0034
Trypanosoma brucei histone deacetylase 4 0.0121 0.0399 0.0822
Echinococcus multilocularis notch 0.0477 0.1799 0.1793
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0136 0.0461 0.0461
Schistosoma mansoni notch 0.0477 0.1799 0.1793
Loa Loa (eye worm) hypothetical protein 0.056 0.2125 0.2125
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0099 0.0313 0.0565
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0134 0.0449 0.0443
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0029 0.0041 0.0034
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0236 0.0854 0.1151
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.011 0.0356 0.0676
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0029 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0477 0.1799 0.1799
Brugia malayi notch-like transmembrane receptor 0.0477 0.1799 0.1799
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.011 0.0356 0.064
Schistosoma mansoni lipoxygenase 0.0087 0.0269 0.0262
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0029 0.0041 0.0034
Echinococcus multilocularis slit 2 protein 0.0477 0.1799 0.1793
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0096 0.0096
Brugia malayi EGF-like domain containing protein 0.0477 0.1799 0.1799
Schistosoma mansoni hypothetical protein 0.0477 0.1799 0.1793
Plasmodium falciparum transporter, putative 0.0044 0.0096 0.042
Trypanosoma cruzi histone deacetylase, putative 0.0091 0.0281 0.0556
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0007 0.0007
Echinococcus multilocularis neural cadherin 0.0477 0.1799 0.1793

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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