Detailed information for compound 897336

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 300.309 | Formula: C16H16N2O4
  • H donors: 2 H acceptors: 2 LogP: 2.42 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(OC)ccc1C(=O)N/N=C/c1ccccc1O
  • InChi: 1S/C16H16N2O4/c1-21-12-7-8-13(15(9-12)22-2)16(20)18-17-10-11-5-3-4-6-14(11)19/h3-10,19H,1-2H3,(H,18,20)/b17-10+
  • InChiKey: UIWHCEGEZAPZJY-LICLKQGHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni jumonji/arid domain-containing protein 0.0048 0.0595 0.062
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0048 0.0595 0.062
Schistosoma mansoni z-protein (S1r protein) 0.0009 0.0034 0.0036
Schistosoma mansoni phd/f-box containing protein 0.0013 0.0089 0.0092
Onchocerca volvulus 0.0232 0.3233 0.761
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0238 0.0554
Loa Loa (eye worm) jmjC domain-containing protein 0.0013 0.0089 0.0133
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0093 0.1243 0.2923
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0465 0.1089
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0238 0.0554
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0047 0.0573 0.1344
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.004 0.0477 0.0713
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0573 0.1344
Schistosoma mansoni hypothetical protein 0.0013 0.0085 0.0089
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0238 0.0356
Echinococcus granulosus transcription factor btf3 0.0029 0.0315 0.0328
Loa Loa (eye worm) hypothetical protein 0.002 0.0195 0.0292
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0013 0.0085 0.0089
Echinococcus multilocularis JmjC domain containing protein 4 0.0013 0.0089 0.0092
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0238 0.0568
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0086 0.0089
Trypanosoma brucei hypothetical protein, conserved 0.011 0.1485 0.3575
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0013 0.0086 0.0089
Schistosoma mansoni jumonji domain containing protein 0.0013 0.0089 0.0092
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0238 0.0554
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0013 0.0089 0.0582
Echinococcus granulosus tar DNA binding protein 0.0065 0.0831 0.0866
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Trichomonas vaginalis penicillin-binding protein, putative 0.011 0.1485 0.3492
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.4148 1
Schistosoma mansoni jumonji domain containing protein 0.0048 0.0595 0.062
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0086 0.0201
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0637 0.1532
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0007 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0315 0.0737
Loa Loa (eye worm) jmjC domain-containing protein 0.0013 0.0089 0.0133
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0831 0.0866
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0142 0.1941 0.2022
Brugia malayi hypothetical protein 0.0189 0.2618 0.3918
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0034 0.0036
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0032 0.036 0.0863
Mycobacterium ulcerans beta-lactamase 0.011 0.1485 0.3492
Trypanosoma cruzi hypothetical protein, conserved 0.0093 0.1243 0.2993
Loa Loa (eye worm) hypothetical protein 0.0043 0.0519 0.0777
Onchocerca volvulus 0.011 0.1485 0.3492
Echinococcus granulosus survival motor neuron protein 1 0.0189 0.2618 0.2727
Brugia malayi TAR-binding protein 0.0065 0.0831 0.1244
Leishmania major basic transcription factor 3a, putative 0.0029 0.0315 0.0754
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0503 0.3381
Entamoeba histolytica hypothetical protein 0.0029 0.0317 0.0742
Schistosoma mansoni dep domain containing protein 0.0009 0.0034 0.0036
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0029 0.0317 0.0331
Echinococcus granulosus beta LACTamase domain containing family member 0.011 0.1485 0.1546
Echinococcus multilocularis jumonji domain containing 1A 0.0013 0.0089 0.0092
Loa Loa (eye worm) hypothetical protein 0.0013 0.0089 0.0133
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.214 0.2138
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0238 0.0568
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0034 0.0036
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0465 0.0484
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0015
Brugia malayi beta-NAC-like protein 0.0029 0.0315 0.0471
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0153 0.1019
Toxoplasma gondii isocitrate dehydrogenase 0.0013 0.0086 0.0563
Schistosoma mansoni survival motor neuron protein 0.0039 0.0458 0.0477
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0034 0.0036
Echinococcus multilocularis GPCR, family 2 0.0013 0.0085 0.0089
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0013 0.0085 0.0089
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0465 0.0484
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0021 0.02 0.0208
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0013 0.0086 0.0201
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0034 0.0052
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Loa Loa (eye worm) hypothetical protein 0.0048 0.0599 0.0897
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0013 0.0089 0.0092
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0238 0.0554
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0573 0.1344
Brugia malayi Calcitonin receptor-like protein seb-1 0.004 0.0477 0.0713
Loa Loa (eye worm) hypothetical protein 0.011 0.1485 0.2222
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0007 0.001 0.0015
Trypanosoma brucei protein kinase, putative 0.0051 0.0637 0.1532
Schistosoma mansoni hypothetical protein 0.0039 0.0458 0.0477
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0296 0.4148 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.004 0.0477 0.0713
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0032 0.036 0.0843
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0013 0.0089 0.0208
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0637 0.4285
Mycobacterium leprae conserved hypothetical protein 0.011 0.1485 1
Brugia malayi isocitrate dehydrogenase 0.0013 0.0086 0.0128
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0142 0.1941 0.2022
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0637 0.1532
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0465 0.0484
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0007 0.001 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0637 0.1496
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0034 0.0052
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0171 0.2357 0.2455
Brugia malayi latrophilin 2 splice variant baaae 0.0027 0.0296 0.0442
Echinococcus multilocularis isocitrate dehydrogenase 0.0013 0.0086 0.0089
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0034 0.0036
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0465 0.1115
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0454 1
Mycobacterium ulcerans esterase/lipase LipP 0.011 0.1485 0.3492
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0153 0.0356
Echinococcus multilocularis lamin dm0 0.0044 0.0531 0.0553
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0086 0.0201
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0637 0.0664
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0021 0.02 0.0465
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0831 0.0866
Loa Loa (eye worm) hypothetical protein 0.0023 0.0238 0.0356
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0472 0.6682 1
Leishmania major hypothetical protein, conserved 0.0013 0.0089 0.0208
Echinococcus multilocularis expressed protein 0.0007 0.001 0.001
Schistosoma mansoni protein phosphatase 2C 0.0013 0.0089 0.0092
Echinococcus granulosus JmjC domain containing protein 4 0.0013 0.0089 0.0092
Onchocerca volvulus 0.0007 0.001 0.0018
Brugia malayi Pre-SET motif family protein 0.0029 0.0324 0.0485
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0015 0.0117 0.0271
Echinococcus multilocularis musashi 0.0044 0.0531 0.0553
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0021 0.0207 0.0215
Brugia malayi MAP kinase sur-1 0.0051 0.0637 0.0954
Schistosoma mansoni transcription factor btf3 0.0029 0.0315 0.0328
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0013 0.0085 0.0128
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0302 0.4247 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0465 0.003
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0637 0.0485
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0047 0.0573 0.1344
Brugia malayi DIX domain containing protein 0.0009 0.0034 0.0052
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0047 0.0573 0.1377
Leishmania major hypothetical protein, conserved 0.011 0.1485 0.3575
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0002 0.0003
Brugia malayi hypothetical protein 0.0029 0.0317 0.0475
Echinococcus multilocularis phd:f box containing protein 0.0013 0.0089 0.0092
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0238 0.0554
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0465 0.0484
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0573 0.1344
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0637 0.1532
Entamoeba histolytica transcription factor BTF3, putative 0.0029 0.0315 0.0737
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0007 0.001 0.0015
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.02 0.0465
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0184 0.2545 0.599
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0007 0.001 0.001
Plasmodium vivax JmjC domain containing protein 0.0013 0.0089 0.0582
Loa Loa (eye worm) hypothetical protein 0.011 0.1485 0.2222
Loa Loa (eye worm) DIX domain-containing protein 0.0009 0.0034 0.0052
Onchocerca volvulus 0.0007 0.001 0.0018
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0007 0.001 0.0015
Onchocerca volvulus 0.0009 0.0034 0.0076
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0238 0.0356
Brugia malayi Intermediate filament tail domain containing protein 0.0044 0.0531 0.0794
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0021 0.02 0.0299
Trichomonas vaginalis penicillin-binding protein, putative 0.011 0.1485 0.3492
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0013 0.0089 0.0582
Echinococcus multilocularis survival motor neuron protein 1 0.0189 0.2618 0.2727
Trypanosoma cruzi transcription factor btf3, putative 0.0029 0.0315 0.0754
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0171 0.2357 0.2455
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0454 0.1063
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0324 0.0337
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0501 0.1203
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Echinococcus granulosus microtubule associated protein 2 0.0675 0.9601 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.2829 0.4234
Plasmodium falciparum basic transcription factor 3b, putative 0.0029 0.0315 0.6931
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.1884 0.1962
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0637 0.0664
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0007 0.001 0.0018
Onchocerca volvulus 0.0007 0.001 0.0018
Mycobacterium tuberculosis Probable lipase LipE 0.011 0.1485 0.1483
Schistosoma mansoni phosphatidylserine receptor 0.0013 0.0089 0.0092
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0238 0.0554
Echinococcus multilocularis tumor protein p63 0.0331 0.4652 0.4846
Mycobacterium ulcerans putative regulatory protein 0.0015 0.0117 0.0271
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0009 0.0034 0.0036
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.1485 0.3492
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Brugia malayi hypothetical protein 0.0009 0.0034 0.0052
Schistosoma mansoni dishevelled 0.0009 0.0034 0.0036
Echinococcus granulosus jumonji domain containing 1A 0.0013 0.0089 0.0092
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0023 0.024 0.0359
Toxoplasma gondii hypothetical protein 0.0009 0.0034 0.0217
Loa Loa (eye worm) G protein alpha subunit 3 0.0007 0.001 0.0015
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0324 0.217
Toxoplasma gondii ABC1 family protein 0.011 0.1485 1
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0047 0.0573 0.0597
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0007 0.001 0.001
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0238 0.0568
Echinococcus multilocularis geminin 0.0478 0.6765 0.7046
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0021 0.02 0.0208
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0013 0.0086 0.0089
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0501 0.1203
Loa Loa (eye worm) hypothetical protein 0.011 0.1485 0.2222
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0015
Echinococcus granulosus expressed protein 0.0007 0.001 0.001
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0007 0.001 0.001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0324 0.0337
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0047 0.0573 0.0597
Brugia malayi hypothetical protein 0.0098 0.131 0.1961
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.1913 0.4608
Brugia malayi acetyltransferase, GNAT family protein 0.0142 0.1941 0.2905
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.014 0.0138
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0637 0.0664
Entamoeba histolytica hypothetical protein 0.0029 0.0317 0.0742
Brugia malayi G-protein alpha subunit 0.0007 0.001 0.0015
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.011 0.1485 0.2222
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0831 0.0866
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0007 0.001 0.001
Brugia malayi Isocitrate dehydrogenase 0.0013 0.0086 0.0128
Mycobacterium tuberculosis Probable hydrolase 0.011 0.1485 0.1483
Schistosoma mansoni jumonji/arid domain-containing protein 0.0048 0.0595 0.062
Entamoeba histolytica G protein alpha subunit, putative 0.0007 0.001 0.0018
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0573 0.1344
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0002 0.0003
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0007 0.001 0.001
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0034 0.0036
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0503 0.118
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0034 0.0036
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0007 0.001 0.0018
Echinococcus granulosus phd:f box containing protein 0.0013 0.0089 0.0092
Loa Loa (eye worm) hypothetical protein 0.004 0.0477 0.0713
Mycobacterium leprae Probable lipase LipE 0.011 0.1485 1
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0009 0.0034 0.0076
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0637 0.0954
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0013 0.0089 0.0208
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0573 0.1344
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0034 0.0036
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0595 0.0891
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0153 0.0151
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0302 0.4247 1
Onchocerca volvulus 0.011 0.1485 0.3492
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0491 0.1151
Onchocerca volvulus 0.0039 0.0458 0.1073
Onchocerca volvulus 0.0023 0.0238 0.0554
Echinococcus granulosus intermediate filament protein 0.0044 0.0531 0.0553
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0007 0.001 0.0015
Loa Loa (eye worm) hypothetical protein 0.011 0.1485 0.2222
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0047 0.0573 0.1377
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0002 0.0003
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Loa Loa (eye worm) hypothetical protein 0.0013 0.0089 0.0133
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0013 0.0086 0.0089
Echinococcus multilocularis lysine specific demethylase 6a 0.0013 0.0089 0.0092
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0238 0.1588
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0047 0.0573 0.1344
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0047 0.0573 0.1344
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0013 0.0085 0.0089
Loa Loa (eye worm) hypothetical protein 0.0015 0.0117 0.0176
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.014 0.0138
Echinococcus granulosus Pleckstrin G protein interacting region 0.0009 0.0034 0.0036
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0302 0.4247 0.6357
Loa Loa (eye worm) oxidoreductase 0.0007 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0015
Loa Loa (eye worm) RNA binding protein 0.0065 0.0831 0.1244
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0831 0.1244
Loa Loa (eye worm) isocitrate dehydrogenase 0.0013 0.0086 0.0128
Brugia malayi jmjC domain containing protein 0.0048 0.0595 0.0891
Onchocerca volvulus 0.0044 0.0531 0.1245
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0171 0.2357 0.2455
Loa Loa (eye worm) hypothetical protein 0.0044 0.0531 0.0794
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0013 0.0085 0.0089
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0831 0.1244
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0465 0.0484
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0007 0.001 0.0018
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.011 0.1485 0.1483
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0465 0.0484
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0637 0.1496
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0491 0.1151
Loa Loa (eye worm) hypothetical protein 0.0021 0.02 0.0299
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0009 0.0034 0.0052
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0007 0.001 0.0018
Mycobacterium tuberculosis Probable conserved lipoprotein 0.011 0.1485 0.1483
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0315 0.0737
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0238 0.1588
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0039 0.0458 0.0685
Loa Loa (eye worm) jmjC domain-containing protein 0.0013 0.0089 0.0133
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0007 0.001 0.0015
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.1485 0.3492
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0238 0.0554
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0171 0.2357 0.2455
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0007 0.001 0.0018
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0637 0.1496
Schistosoma mansoni transcription factor LCR-F1 0.0029 0.0317 0.0331
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0086 0.0089
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0503 0.0524
Loa Loa (eye worm) hypothetical protein 0.0013 0.0089 0.0133
Plasmodium falciparum GAF domain-related protein, putative 0.0015 0.0117 0.2552
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0465 0.1115
Schistosoma mansoni hypothetical protein 0.0478 0.6765 0.7046
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0013 0.0086 0.0201
Echinococcus multilocularis beta LACTamase domain containing family member 0.011 0.1485 0.1546
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0002 0.0003
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0034 0.0036
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0007 0.001 0.001
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0007 0.001 0.0015
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0007 0.001 0.0015
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0302 0.4247 1
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0637 0.1496
Brugia malayi jmjC domain containing protein 0.0048 0.0595 0.0891
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0007 0.001 0.001
Brugia malayi jmjC domain containing protein 0.0013 0.0089 0.0133
Mycobacterium tuberculosis Conserved protein 0.011 0.1485 0.1483
Loa Loa (eye worm) acetyltransferase 0.0142 0.1941 0.2905
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0632 0.1518
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0637 0.1532
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0296 0.0442
Toxoplasma gondii isocitrate dehydrogenase 0.0013 0.0086 0.0563
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0153 0.3349
Toxoplasma gondii hypothetical protein 0.0048 0.0589 0.3958
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0015 0.0117 0.0115
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0007 0.001 0.0015
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0007 0.001 0.001
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0032 0.036 0.0843
Echinococcus granulosus tumor protein p63 0.0331 0.4652 0.4846
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0238 0.0554
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.011 0.1485 0.1546
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0021 0.0207 0.0215
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0324 0.0337
Mycobacterium ulcerans hypothetical protein 0.011 0.1485 0.3492
Onchocerca volvulus 0.0302 0.4247 1
Mycobacterium ulcerans lipase LipD 0.011 0.1485 0.3492
Loa Loa (eye worm) hypothetical protein 0.011 0.1485 0.2222
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0171 0.2357 0.2455
Loa Loa (eye worm) hypothetical protein 0.0023 0.0238 0.0356
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0153 0.5
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0093 0.1243 0.2923
Onchocerca volvulus 0.0029 0.0324 0.0758
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0465 0.0484
Leishmania major hypothetical protein, conserved 0.0093 0.1243 0.2993
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0086 0.0201
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0047 0.0573 0.1344
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0637 0.1532
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.011 0.1485 0.1546
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0324 0.0337
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0048 0.0595 0.062
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0007 0.001 0.001
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0501 0.1203
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0501 0.1203
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0007 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0029 0.0317 0.0331
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0831 0.0866
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0238 0.0356
Loa Loa (eye worm) hypothetical protein 0.0098 0.131 0.1961
Loa Loa (eye worm) beta-lactamase 0.011 0.1485 0.2222
Onchocerca volvulus 0.0048 0.0599 0.1407
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0465 0.0696
Mycobacterium tuberculosis Conserved protein 0.011 0.1485 0.1483
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0302 0.4247 1
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0007 0.001 0.001
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0007 0.001 0.0018
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0007 0.001 0.001
Trypanosoma brucei transcription factor BTF3, putative 0.0029 0.0315 0.0754
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0324 0.0337
Leishmania major mitochondrial DNA polymerase beta 0.0296 0.4148 1
Brugia malayi beta-lactamase family protein 0.011 0.1485 0.2222
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0015
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.0089 0.0092
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0007 0.001 0.001
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0637 0.1532
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.014 0.0138
Mycobacterium ulcerans hypothetical protein 0.0156 0.214 0.5035
Trichomonas vaginalis set domain proteins, putative 0.0232 0.3233 0.761
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0465 0.0484
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0013 0.0086 0.185
Brugia malayi regulator of G-protein signaling egl-10 0.0009 0.0034 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0637 0.0664
Schistosoma mansoni lamin 0.0044 0.0531 0.0553
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0238 0.0235
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0047 0.0573 0.1377
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0007 0.001 0.0015
Echinococcus granulosus lysine specific demethylase 5A 0.0048 0.0595 0.062
Toxoplasma gondii hypothetical protein 0.0015 0.0117 0.0777
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0044 0.0531 0.0794
Trypanosoma cruzi hypothetical protein, conserved 0.011 0.1485 0.3575
Brugia malayi jmjC domain containing protein 0.0013 0.0089 0.0133
Schistosoma mansoni dishevelled 0.0009 0.0034 0.0036
Brugia malayi RNA binding protein 0.0065 0.0831 0.1244
Loa Loa (eye worm) hypothetical protein 0.0009 0.0034 0.0052
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0013 0.0086 0.0084
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0648 0.921 0.9593
Schistosoma mansoni intermediate filament proteins 0.0044 0.0531 0.0553
Echinococcus granulosus geminin 0.0478 0.6765 0.7046
Plasmodium falciparum JmjC domain-containing protein, putative 0.0013 0.0089 0.1914
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0007 0.001 0.001
Brugia malayi Pre-SET motif family protein 0.0204 0.2829 0.4234
Brugia malayi jmjC domain containing protein 0.0013 0.0089 0.0133
Schistosoma mansoni hypothetical protein 0.0013 0.0085 0.0089
Loa Loa (eye worm) hypothetical protein 0.0017 0.0153 0.023
Loa Loa (eye worm) transcription factor SMAD2 0.0098 0.1306 0.1955
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0238 0.0235
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.1913 0.4608
Mycobacterium tuberculosis Conserved protein 0.011 0.1485 0.1483
Loa Loa (eye worm) hypothetical protein 0.0029 0.0324 0.0485
Loa Loa (eye worm) hypothetical protein 0.002 0.0195 0.0292
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.1913 0.4608
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0007 0.001 0.0018
Toxoplasma gondii GAF domain-containing protein 0.0015 0.0117 0.0777
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0302 0.4247 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0047 0.0573 0.1344
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0302 0.4247 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0324 0.0337
Loa Loa (eye worm) MH2 domain-containing protein 0.0098 0.1306 0.1955
Plasmodium vivax hypothetical protein, conserved 0.011 0.1485 1
Brugia malayi jmjC domain containing protein 0.0013 0.0089 0.0133
Loa Loa (eye worm) hypothetical protein 0.0021 0.0207 0.0309
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0021 0.02 0.0299
Loa Loa (eye worm) ICD-1 protein 0.0029 0.0315 0.0471
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0013 0.0089 0.0208
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0007 0.001 0.001
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0007 0.0002 0.0002
Brugia malayi hypothetical protein 0.0007 0.001 0.0015
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0007 0.001 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0002 0.0003
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0002 0.0002
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Plasmodium vivax SET domain protein, putative 0.0029 0.0324 0.217
Schistosoma mansoni GTP-binding protein alpha subunit 0.0007 0.001 0.001
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0007 0.001 0.001
Echinococcus multilocularis lamin 0.0044 0.0531 0.0553
Mycobacterium ulcerans putative regulatory protein 0.0015 0.0117 0.0271
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0086 0.0089
Mycobacterium ulcerans hypothetical protein 0.0023 0.0238 0.0554
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0021 0.02 0.0465
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0117 0.0777
Entamoeba histolytica hypothetical protein 0.0029 0.0317 0.0742
Echinococcus multilocularis transcription factor btf3 0.0029 0.0315 0.0328
Brugia malayi MH2 domain containing protein 0.0098 0.1306 0.1955
Trichomonas vaginalis esterase, putative 0.011 0.1485 0.3492
Onchocerca volvulus 0.011 0.1485 0.3492
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0831 0.0866
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0007 0.001 0.0018
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0007 0.0002 0.0003
Echinococcus granulosus lamin 0.0044 0.0531 0.0553
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0171 0.2357 0.3528
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0238 0.0554
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0013 0.0086 0.0563
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0209 0.2909 0.2907
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0015 0.0117 0.0115
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.014 0.0138
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0007 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0085 0.0128
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.011 0.1485 0.2222
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0465 0.1089
Toxoplasma gondii NAC domain-containing protein 0.0029 0.0315 0.211
Schistosoma mansoni hypothetical protein 0.0013 0.0085 0.0089
Loa Loa (eye worm) hypothetical protein 0.0009 0.0034 0.0052
Loa Loa (eye worm) hypothetical protein 0.011 0.1485 0.2222
Schistosoma mansoni microtubule-associated protein tau 0.0675 0.9601 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0153 0.023
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0171 0.2357 0.2455
Echinococcus granulosus GPCR family 2 0.0013 0.0085 0.0089
Schistosoma mansoni GTP-binding protein alpha subunit 0.0007 0.001 0.001
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0029 0.0317 0.0331
Echinococcus granulosus lysine specific demethylase 6a 0.0013 0.0089 0.0092
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0503 0.3381
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0302 0.4247 1
Schistosoma mansoni lamin 0.0044 0.0531 0.0553
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0021 0.02 0.0208
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0047 0.0573 0.1377
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0302 0.4247 1
Loa Loa (eye worm) hypothetical protein 0.0098 0.131 0.1961
Loa Loa (eye worm) hypothetical protein 0.0009 0.0034 0.0052
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0465 0.1089
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0302 0.4247 1
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0007 0.001 0.0015
Brugia malayi Latrophilin receptor protein 2 0.0013 0.0085 0.0128
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0465 0.1115
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0171 0.2357 0.2455
Trypanosoma cruzi hypothetical protein, conserved 0.0093 0.1243 0.2993
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.011 0.1485 0.1483
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0007 0.001 0.001
Trypanosoma cruzi transcription factor btf3, putative 0.0029 0.0315 0.0754
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0238 0.0554
Loa Loa (eye worm) hypothetical protein 0.0017 0.0153 0.023
Brugia malayi cytoplasmic intermediate filament protein 0.0023 0.024 0.0359
Brugia malayi hypothetical protein 0.0009 0.0034 0.0052
Loa Loa (eye worm) hypothetical protein 0.0017 0.0153 0.023
Toxoplasma gondii hypothetical protein 0.0041 0.0491 0.3296
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0599 0.0624
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0573 0.1344
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0007 0.001 0.001
Onchocerca volvulus Huntingtin homolog 0.0098 0.131 0.3081
Mycobacterium tuberculosis Probable lipase LipD 0.011 0.1485 0.1483
Brugia malayi N-terminal motif family protein 0.0184 0.2545 0.3809
Brugia malayi intermediate filament protein 0.0044 0.0531 0.0794
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0465 0.1089
Brugia malayi beta-lactamase family protein 0.011 0.1485 0.2222
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0637 0.1532
Entamoeba histolytica hypothetical protein 0.0029 0.0315 0.0737
Brugia malayi beta-lactamase 0.011 0.1485 0.2222
Brugia malayi follicle stimulating hormone receptor 0.0472 0.6682 1
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0302 0.4247 1
Trypanosoma cruzi hypothetical protein, conserved 0.011 0.1485 0.3575
Schistosoma mansoni hypothetical protein 0.0013 0.0085 0.0089
Echinococcus multilocularis lysine specific demethylase 5A 0.0048 0.0595 0.062
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.011 0.1485 0.3492
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0047 0.0573 0.1377
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0315 0.0737
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0007 0.001 0.0015
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0503 0.118
Onchocerca volvulus 0.0044 0.0531 0.1245
Loa Loa (eye worm) hypothetical protein 0.0184 0.2545 0.3809
Entamoeba histolytica hypothetical protein 0.0029 0.0317 0.0742
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0093 0.1243 0.2993
Loa Loa (eye worm) hypothetical protein 0.0023 0.0238 0.0356
Mycobacterium leprae conserved hypothetical protein 0.0015 0.0117 0.0777
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0831 0.0866
Loa Loa (eye worm) hypothetical protein 0.0189 0.2618 0.3918
Mycobacterium tuberculosis Probable esterase LipL 0.011 0.1485 0.1483
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.0089 0.0092
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0047 0.0573 0.1344
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.1485 0.3492
Schistosoma mansoni regulator of G protein signaling 0.0009 0.0034 0.0036
Echinococcus multilocularis microtubule associated protein 2 0.0675 0.9601 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0013 0.0085 0.0128
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0007 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0153 0.023
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0171 0.2357 0.3528
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0302 0.4247 0.6357
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0007 0.001 0.0015
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0465 0.1115
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0324 0.0337
Onchocerca volvulus Huntingtin homolog 0.0098 0.131 0.3081
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0309 0.0321
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0503 0.3381
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0117 0.0271
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0637 0.0664
Toxoplasma gondii hypothetical protein 0.0015 0.0117 0.0777
Loa Loa (eye worm) intermediate filament protein 0.0044 0.0531 0.0794
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0831 0.1244
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0009 0.0034 0.0036
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0047 0.0573 0.0597
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0491 0.1151
Plasmodium vivax basic transcription factor 3b, putative 0.0029 0.0315 0.211
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0039 0.0465 0.0696
Echinococcus granulosus lamin dm0 0.0044 0.0531 0.0553
Schistosoma mansoni hypothetical protein 0.0478 0.6765 0.7046
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0003
Schistosoma mansoni hypothetical protein 0.0027 0.0296 0.0308
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.4148 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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