Detailed information for compound 929703

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 345.393 | Formula: C18H23N3O4
  • H donors: 1 H acceptors: 3 LogP: 2.6 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)[C@@H]1CC[C@H](CC1)Nc1cnc2c(n1)cc(c(c2)OC)OC
  • InChi: 1S/C18H23N3O4/c1-23-15-8-13-14(9-16(15)24-2)21-17(10-19-13)20-12-6-4-11(5-7-12)18(22)25-3/h8-12H,4-7H2,1-3H3,(H,20,21)/t11-,12-
  • InChiKey: FTXKUBNATJTYSH-HAQNSBGRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens platelet-derived growth factor receptor, alpha polypeptide Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.01 0.0132
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0058 0.0287 0.0287
Schistosoma mansoni endoplasmin 0.0034 0.0143 0.0166
Trypanosoma brucei heat shock protein, putative 0.0034 0.0143 0.0601
Loa Loa (eye worm) hypothetical protein 0.0149 0.0829 0.1413
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.006 0.1451
Schistosoma mansoni biogenic amine receptor 0.0049 0.0233 0.027
Toxoplasma gondii ran binding protein 0.0353 0.2048 0.3487
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0143 0.3456
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.04 0.2333 0.2333
Echinococcus multilocularis RING finger and transmembrane domain containing protein 0.0018 0.0046 0.0046
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.04 0.2333 1
Loa Loa (eye worm) TYRA-2 protein 0.0049 0.0233 0.0396
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0059 0.0243
Trichomonas vaginalis rotamase, putative 0.0034 0.0144 0.0207
Echinococcus granulosus neuropeptide s receptor 0.0049 0.0233 0.027
Echinococcus multilocularis survival motor neuron protein 1 0.0505 0.2962 0.2962
Trichomonas vaginalis ion channel nompc, putative 0.0018 0.0046 0.0041
Loa Loa (eye worm) hypothetical protein 0.0034 0.0142 0.0242
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0263 0.0448
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0049 0.0233 0.027
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Trypanosoma brucei isocitrate dehydrogenase, putative 0.04 0.2333 1
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0049 0.0233 0.0233
Echinococcus multilocularis isocitrate dehydrogenase 0.04 0.2333 0.2333
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0353 0.2048 0.8775
Plasmodium vivax E3 ubiquitin-protein ligase, putative 0.0018 0.0046 0.0041
Onchocerca volvulus 0.0049 0.0233 0.0396
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0325 0.1884 0.3211
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0049 0.0233 0.0396
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0046 0.0187
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Trypanosoma cruzi heat shock protein 90, putative 0.0027 0.0101 0.0423
Loa Loa (eye worm) hypothetical protein 0.0151 0.0839 0.1431
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0991 0.5867 1
Schistosoma mansoni hypothetical protein 0.0018 0.0046 0.0054
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.006 0.0247
Onchocerca volvulus 0.0012 0.0011 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0233 0.0233
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0018 0.0046 0.0054
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0233 0.027
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0101 0.0135
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.006 0.0247
Schistosoma mansoni zinc finger protein 0.0018 0.0046 0.0054
Trichomonas vaginalis cell cycle control protein cwf24, putative 0.0018 0.0047 0.0042
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Trichomonas vaginalis ankyrin, putative 0.0018 0.0046 0.0041
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0991 0.5867 1
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Schistosoma mansoni nAChR subunit 0.0012 0.0011 0.0013
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0233 0.0396
Trypanosoma brucei SNF2 family N-terminal domain/Ring finger domain containing protein, putative 0.0018 0.0046 0.0187
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Onchocerca volvulus 0.0049 0.0233 0.0396
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0233 0.0233
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.006 0.007
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0154 0.0154
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0027 0.0101 0.0423
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Echinococcus granulosus G protein coupled receptor 139 0.0049 0.0233 0.027
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0233 0.027
Schistosoma mansoni heat shock protein 0.0014 0.0023 0.0026
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Plasmodium vivax E3 ubiquitin-protein ligase RNF5, putative 0.0018 0.0046 0.0041
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0049 0.0233 0.027
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0371 0.0596
Entamoeba histolytica zinc finger domain containing protein 0.0018 0.0046 0.0683
Leishmania major hypothetical protein, conserved 0.0018 0.0046 0.0187
Loa Loa (eye worm) hypothetical protein 0.0149 0.0829 0.1413
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Schistosoma mansoni biogenic amine receptor 0.0049 0.0233 0.027
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0353 0.2048 0.349
Giardia lamblia Kinase 0.0018 0.0048 0.019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.0079
Brugia malayi hypothetical protein 0.0018 0.0046 0.0079
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0072 0.0371 0.0596
Brugia malayi Probable isocitrate dehydrogenase 0.0049 0.023 0.0392
Schistosoma mansoni hypothetical protein 0.0991 0.5867 0.6806
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0226 0.0262
Schistosoma mansoni neuropeptide receptor 0.1315 0.7803 0.9053
Brugia malayi hypothetical protein 0.0018 0.0046 0.0079
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Brugia malayi Muscleblind-like protein 0.0149 0.0829 0.1413
Echinococcus granulosus endoplasmin 0.0027 0.0101 0.0118
Echinococcus multilocularis 0.0018 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Loa Loa (eye worm) hypothetical protein 0.0092 0.0492 0.0838
Echinococcus granulosus peptide allatostatin:somatostatin 0.0049 0.0233 0.027
Toxoplasma gondii Hsp90 domain-containing protein 0.0014 0.0023 0.0034
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0144 0.0604
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0049 0.0233 0.027
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0049 0.0233 0.027
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0353 0.2048 0.8775
Brugia malayi hypothetical protein 0.0018 0.0046 0.0079
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0018 0.0046 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0233 0.0233
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0018 0.0046 0.0041
Trypanosoma brucei Heat shock protein 83, putative 0.0034 0.0143 0.0601
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Echinococcus multilocularis heat shock protein 90 0.0027 0.0101 0.0101
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0012 0.0011 0.0013
Brugia malayi neuropeptide F receptor 0.0049 0.0233 0.0396
Onchocerca volvulus 0.0353 0.2048 0.349
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.006 0.0247
Echinococcus granulosus hypothetical protein 0.0049 0.0233 0.027
Leishmania major hypothetical protein, conserved 0.0018 0.0046 0.0187
Onchocerca volvulus 0.0353 0.2048 0.349
Echinococcus multilocularis ring finger protein 170 0.0018 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Entamoeba histolytica zinc finger domain containing protein 0.0018 0.0046 0.0683
Echinococcus granulosus muscleblind protein 0.0149 0.0829 0.0962
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0263 0.0263
Loa Loa (eye worm) hypothetical protein 0.0353 0.2048 0.349
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0049 0.0233 0.0396
Plasmodium vivax endoplasmin, putative 0.0034 0.0143 0.0206
Echinococcus multilocularis geminin 0.0541 0.3178 0.3178
Leishmania major DNA repair protein-like protein 0.0018 0.0046 0.0187
Leishmania major isocitrate dehydrogenase, putative 0.0049 0.023 0.0975
Plasmodium vivax DNA repair protein RAD5, putative 0.0018 0.0046 0.0041
Leishmania major hypothetical protein, conserved 0.0018 0.0046 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0353 0.2048 0.349
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Toxoplasma gondii hypothetical protein 0.0018 0.0046 0.0074
Onchocerca volvulus 0.0049 0.0233 0.0396
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0233 0.027
Brugia malayi hypothetical protein 0.0049 0.0233 0.0396
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0233 0.027
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0233 0.0233
Leishmania major hypothetical protein, unknown function 0.0018 0.0046 0.0187
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0018 0.0046 0.0041
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0018 0.0046 0.0041
Onchocerca volvulus 0.0012 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0054 0.0263 0.0448
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0233 0.0233
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.006 0.0103
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.01 0.0132
Echinococcus granulosus ring finger protein 113a 0.0018 0.0047 0.0055
Echinococcus granulosus cell growth regulator with ring finger domain 0.0018 0.0046 0.0054
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Onchocerca volvulus 0.0049 0.0233 0.0396
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0341 0.0396
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0233 0.027
Mycobacterium ulcerans heat shock protein 90 0.0027 0.0101 0.013
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.0049 0.023 0.023
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0052 0.0248 0.0248
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0049 0.0233 0.027
Trichomonas vaginalis glutaminase, putative 0.0546 0.3202 0.5441
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0052 0.0248 0.0423
Echinococcus granulosus neuropeptide receptor 0.0049 0.0233 0.027
Loa Loa (eye worm) hypothetical protein 0.0058 0.0287 0.0489
Entamoeba histolytica hypothetical protein 0.0036 0.0154 0.3759
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0233 0.0396
Onchocerca volvulus 0.0188 0.1064 0.1814
Brugia malayi B-box zinc finger family protein 0.0018 0.0046 0.0079
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.0079
Echinococcus multilocularis expressed protein 0.0035 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Echinococcus granulosus neuropeptide receptor A26 0.0049 0.0233 0.027
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Echinococcus granulosus glycine receptor subunit alpha 1 0.0058 0.0287 0.0333
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0353 0.2048 0.349
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0341 0.0894
Schistosoma mansoni TRABID protein (C64 family) 0.0353 0.2048 0.2376
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0049 0.0233 0.027
Loa Loa (eye worm) ACC-1 protein 0.0012 0.0011 0.0019
Trypanosoma brucei heat shock protein 84, putative 0.0014 0.0023 0.0085
Entamoeba histolytica zinc finger domain containing protein 0.0018 0.0046 0.0683
Echinococcus granulosus dro:myosuppressin receptor 0.0049 0.0233 0.027
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.01 0.2219
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0014 0.0023 0.0023
Echinococcus multilocularis G protein coupled receptor 139 0.1315 0.7803 0.7803
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0011 0.0019
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Echinococcus granulosus SWI:SNF matrix associated 0.0991 0.5867 0.6806
Echinococcus granulosus neuropeptide receptor 0.1315 0.7803 0.9053
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.04 0.2333 1
Schistosoma mansoni ring finger protein 151 0.0018 0.0046 0.0054
Onchocerca volvulus 0.0049 0.0233 0.0396
Schistosoma mansoni hypothetical protein 0.0018 0.0047 0.0055
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.0049 0.023 0.0392
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0263 0.0305
Echinococcus granulosus E3 ubiquitin protein ligase LRSAM1 0.0018 0.0046 0.0054
Onchocerca volvulus Putative RING finger protein 207 0.0018 0.0046 0.0079
Plasmodium falciparum endoplasmin, putative 0.0021 0.0064 0.0071
Schistosoma mansoni hypothetical protein 0.0103 0.0556 0.0645
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Echinococcus granulosus RING finger protein 185 0.0018 0.0046 0.0054
Brugia malayi Tachykinin-like peptides receptor 99D 0.0049 0.0233 0.0396
Loa Loa (eye worm) isocitrate dehydrogenase 0.04 0.2333 0.3977
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Schistosoma mansoni growth hormone secretagogue receptor 0.0049 0.0233 0.027
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Brugia malayi Glycosyl hydrolases family 31 protein 0.0325 0.1884 0.3211
Brugia malayi Zinc finger, C2H2 type family protein 0.0018 0.0046 0.0079
Schistosoma mansoni neuropeptide receptor 0.0049 0.0233 0.027
Plasmodium falciparum zinc finger protein, putative 0.0018 0.0046 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Brugia malayi Cation transporter family protein 0.0058 0.0287 0.0489
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.04 0.2333 0.2333
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Echinococcus multilocularis neuropeptide receptor A26 0.0049 0.0233 0.0233
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0018 0.0046 0.0046
Onchocerca volvulus 0.0049 0.0233 0.0396
Echinococcus granulosus E3 ubiquitin protein ligase MYLIP 0.0018 0.0046 0.0054
Echinococcus multilocularis SWI:SNF matrix associated 0.0991 0.5867 0.5867
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0223 0.0259
Leishmania major hypothetical protein, conserved 0.0353 0.2048 0.8775
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0011 0.0019
Brugia malayi hypothetical protein 0.0049 0.0233 0.0396
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0233 0.0233
Onchocerca volvulus 0.0018 0.0046 0.0079
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0033 0.0056
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0144 0.0604
Brugia malayi Melatonin receptor type 1A 0.0049 0.0233 0.0396
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.01 0.0132
Echinococcus multilocularis neuropeptide receptor 0.1315 0.7803 0.7803
Brugia malayi Endoplasmin precursor 0.0034 0.0143 0.0244
Schistosoma mansoni peter pan-related 0.0018 0.0046 0.0054
Brugia malayi Probable isocitrate dehydrogenase 0.0049 0.023 0.0392
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.006 0.0065
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0233 0.027
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0236 0.0403
Trypanosoma cruzi Eukaryotic translation initiation factor 2-alpha kinase 2 0.0069 0.035 0.1489
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0233 0.0233
Schistosoma mansoni zinc finger protein 0.0353 0.2048 0.2376
Trichomonas vaginalis hypothetical protein 0.0018 0.0046 0.0041
Schistosoma mansoni hypothetical protein 0.0049 0.0233 0.027
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0049 0.0233 0.0396
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.006 0.0103
Brugia malayi hypothetical protein 0.0018 0.0046 0.0079
Echinococcus granulosus allatostatin A receptor 0.0049 0.0233 0.027
Brugia malayi Dopamine receptor protein 1 0.0049 0.0233 0.0396
Brugia malayi Cation transporter family protein 0.0012 0.0011 0.0019
Plasmodium vivax heat shock protein 86, putative 0.0034 0.0143 0.0206
Brugia malayi hypothetical protein 0.0488 0.2858 0.4872
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0049 0.0233 0.0233
Schistosoma mansoni hypothetical protein 0.0034 0.0142 0.0165
Trypanosoma brucei hypothetical protein, conserved 0.0353 0.2048 0.8775
Trypanosoma brucei heat shock protein, putative 0.0034 0.0143 0.0601
Trichomonas vaginalis rotamase, putative 0.0035 0.0149 0.0215
Schistosoma mansoni isocitrate dehydrogenase 0.0049 0.023 0.0267
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0049 0.0233 0.027
Onchocerca volvulus 0.0012 0.0011 0.0019
Echinococcus granulosus glycine receptor subunit beta 0.0058 0.0287 0.0333
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0233 0.027
Brugia malayi glutaminase DH11.1 0.0546 0.3202 0.5458
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.0049 0.023 0.0392
Schistosoma mansoni survival motor neuron protein 0.0103 0.0556 0.0645
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Giardia lamblia Kinase, NEK 0.0018 0.0048 0.019
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0033 0.0033
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0143 0.3456
Loa Loa (eye worm) hypothetical protein 0.0488 0.2858 0.4872
Schistosoma mansoni heat shock protein 0.0034 0.0143 0.0166
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0233 0.027
Wolbachia endosymbiont of Brugia malayi isocitrate dehydrogenase 0.0049 0.023 1
Schistosoma mansoni nAChR subunit 0.0012 0.0011 0.0013
Brugia malayi mbt repeat family protein 0.0048 0.0223 0.0381
Brugia malayi G protein-coupled receptor F59B2.13 0.0049 0.0233 0.0396
Schistosoma mansoni hypothetical protein 0.0353 0.2048 0.2376
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0149 0.0253
Entamoeba histolytica hypothetical protein 0.0018 0.0046 0.0683
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0223 0.0259
Leishmania major hypothetical protein, conserved 0.0018 0.0046 0.0187
Echinococcus granulosus geminin 0.0541 0.3178 0.3687
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0353 0.2048 0.2048
Schistosoma mansoni ap endonuclease 0.002 0.006 0.007
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0012 0.0011 0.0013
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0233 0.027
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0263 0.0305
Echinococcus multilocularis RING finger protein 185 0.0018 0.0046 0.0046
Plasmodium falciparum E3 ubiquitin-protein ligase, putative 0.0018 0.0046 0.0041
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Loa Loa (eye worm) RING finger protein 20 0.0018 0.0046 0.0079
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0144 0.024
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0014 0.0023 0.0039
Schistosoma mansoni nAChR subunit 0.0012 0.0011 0.0013
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0072 0.0371 1
Schistosoma mansoni amine GPCR 0.0049 0.0233 0.027
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Trichomonas vaginalis STE family protein kinase 0.0069 0.035 0.056
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Toxoplasma gondii isocitrate dehydrogenase 0.04 0.2333 0.3974
Loa Loa (eye worm) heat shock protein 90 0.0034 0.0143 0.0244
Leishmania major hypothetical protein, conserved 0.0018 0.0046 0.0187
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0033 0.0033
Leishmania major alpha glucosidase II subunit, putative 0.0072 0.0371 0.1579
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0991 0.5867 0.6806
Echinococcus multilocularis serotonin receptor 0.0049 0.0233 0.0233
Onchocerca volvulus 0.0049 0.0233 0.0396
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0012 0.0011 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0233 0.027
Echinococcus multilocularis endoplasmin 0.0027 0.0101 0.0101
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0371 0.1579
Loa Loa (eye worm) melatonin receptor type 1A 0.0049 0.0233 0.0396
Trypanosoma brucei heat shock protein, putative 0.0034 0.0143 0.0601
Brugia malayi hypothetical protein 0.0049 0.0233 0.0396
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Loa Loa (eye worm) LGC-31 protein 0.0012 0.0011 0.0019
Brugia malayi brahma associated protein 60 kDa 0.0991 0.5867 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0049 0.0233 0.0233
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Toxoplasma gondii SWI2/SNF2-containing protein RAD5 0.0018 0.0046 0.0074
Trypanosoma cruzi hypothetical protein, conserved 0.0353 0.2048 0.8775
Schistosoma mansoni hypothetical protein 0.0016 0.0033 0.0038
Trypanosoma brucei eukaryotic translation initiation factor 2-alpha kinase 2 0.0069 0.035 0.1489
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.0079
Schistosoma mansoni inhibitor of apoptosis 1 diap1 0.0018 0.0046 0.0054
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0233 0.0233
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0033 0.0056
Brugia malayi hypothetical protein 0.0018 0.0046 0.0079
Echinococcus granulosus glycine receptor subunit beta 0.0058 0.0287 0.0333
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0012 0.0011 0.0011
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0371 0.0596
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Leishmania major hypothetical protein, conserved 0.0018 0.0046 0.0187
Brugia malayi Hsp90 protein 0.0014 0.0023 0.0039
Trichomonas vaginalis endoplasmin, putative 0.0021 0.0064 0.0071
Onchocerca volvulus Putative nachr subunit 0.0012 0.0011 0.0019
Echinococcus granulosus RING finger and transmembrane domain containing protein 0.0018 0.0046 0.0054
Plasmodium vivax zinc finger protein, putative 0.0018 0.0046 0.0041
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0353 0.2048 0.2048
Loa Loa (eye worm) ACC-1 protein 0.0012 0.0011 0.0019
Onchocerca volvulus 0.0018 0.0046 0.0079
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0341 0.1235
Echinococcus multilocularis GPCR, family 2 0.0016 0.0033 0.0033
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0058 0.0287 0.0287
Leishmania major hypothetical protein, conserved 0.0018 0.0046 0.0187
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0223 0.0381
Brugia malayi Serotonin receptor 0.0049 0.0233 0.0396
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Schistosoma mansoni nAChR subunit 0.0012 0.0011 0.0013
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0049 0.0233 0.0396
Schistosoma mansoni amine GPCR 0.0049 0.0233 0.027
Schistosoma mansoni nAChR subunit 0.0012 0.0011 0.0013
Echinococcus multilocularis serotonin receptor 0.0049 0.0233 0.0233
Giardia lamblia Grp94/Hsp90 0.0027 0.0101 0.5699
Brugia malayi hypothetical protein 0.0049 0.0233 0.0396
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Toxoplasma gondii exonuclease III APE 0.002 0.006 0.0098
Trypanosoma cruzi Eukaryotic translation initiation factor 2-alpha kinase 2 0.0068 0.0348 0.1481
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.0049 0.023 0.0392
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Brugia malayi RING zinc finger protein 0.0018 0.0046 0.0079
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0058 0.0287 0.0489
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0233 0.027
Trypanosoma cruzi hypothetical protein, conserved 0.0353 0.2048 0.8775
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0233 0.027
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0341 0.1452
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0058 0.0287 0.0287
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0233 0.027
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0012 0.0011 0.0019
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.0079
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Trypanosoma brucei predicted zinc finger protein 0.0018 0.0046 0.0187
Schistosoma mansoni microtubule-associated protein tau 0.1451 0.862 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0143 0.0601
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0012 0.0011 0.0011
Loa Loa (eye worm) GABA receptor subunit 0.0053 0.0254 0.0432
Brugia malayi follicle stimulating hormone receptor 0.0049 0.0233 0.0396
Schistosoma mansoni hypothetical protein 0.0016 0.0033 0.0038
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Onchocerca volvulus 0.0049 0.0233 0.0396
Brugia malayi putative neuropeptide receptor NPR1 0.0049 0.0233 0.0396
Echinococcus multilocularis orexin receptor type 2 0.0049 0.0233 0.0233
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0049 0.0233 0.0396
Echinococcus granulosus tachykinin peptides receptor 99D 0.0049 0.0233 0.027
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Echinococcus multilocularis neutral alpha glucosidase AB 0.0072 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Echinococcus granulosus expressed protein 0.0035 0.0149 0.0172
Brugia malayi GnHR receptor homolog 0.0049 0.0233 0.0396
Onchocerca volvulus 0.0018 0.0046 0.0079
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Brugia malayi hypothetical protein 0.0092 0.0492 0.0838
Brugia malayi Dopamine receptor 0.0049 0.0233 0.0396
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Echinococcus granulosus nAChR subunit 0.0012 0.0011 0.0013
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0049 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0353 0.2048 0.349
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0149 0.0215
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Loa Loa (eye worm) hypothetical protein 0.0016 0.0033 0.0056
Trypanosoma brucei heat shock protein, putative 0.0034 0.0143 0.0601
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0018 0.0046 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0353 0.2048 0.349
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Onchocerca volvulus 0.0103 0.0556 0.0947
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0103 0.0556 0.0947
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0012 0.0011 0.0013
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0011 0.0019
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0011 0.0019
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Trypanosoma brucei glycosyl hydrolase-like protein 0.0027 0.01 0.0417
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0233 0.027
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0353 0.2048 0.349
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0233 0.027
Plasmodium vivax serine/threonine protein kinase, putative 0.0069 0.035 0.056
Loa Loa (eye worm) hypothetical protein 0.0505 0.2962 0.5048
Toxoplasma gondii hypothetical protein 0.0018 0.0046 0.0074
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0049 0.0233 0.0396
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0018 0.0046 0.0041
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0012 0.0011 0.0019
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0049 0.0233 0.0233
Entamoeba histolytica zinc finger domain containing protein 0.0018 0.0046 0.0683
Brugia malayi sulfakinin receptor protein 0.0049 0.0233 0.0396
Echinococcus granulosus ring finger protein 170 0.0018 0.0046 0.0054
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0046 0.0187
Trichomonas vaginalis ankyrin, putative 0.0018 0.0046 0.0041
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0012 0.0011 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0233 0.027
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0072 0.0371 0.0627
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0012 0.0011 0.0019
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.01 0.0417
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Brugia malayi Serotonin receptor 0.0049 0.0233 0.0396
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Trichomonas vaginalis ap endonuclease, putative 0.002 0.006 0.0065
Onchocerca volvulus 0.0049 0.0233 0.0396
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Onchocerca volvulus 0.0018 0.0046 0.0079
Chlamydia trachomatis DNA topoisomerase I 0.0991 0.5867 0.5
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0012 0.0011 0.0019
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Entamoeba histolytica hypothetical protein 0.0018 0.0046 0.0683
Echinococcus multilocularis nAChR subunit 0.0012 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0049 0.0233 0.027
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Loa Loa (eye worm) MBCTL1 0.0054 0.0263 0.0448
Brugia malayi heat shock protein 90 0.0034 0.0143 0.0244
Echinococcus multilocularis allatostatin A receptor 0.0049 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0046 0.0187
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0991 0.5867 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0049 0.0233 0.027
Echinococcus multilocularis glycine receptor subunit beta 0.0058 0.0287 0.0287
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.006 0.2537
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Treponema pallidum heat shock protein 90 0.0027 0.0101 1
Trichomonas vaginalis ap endonuclease, putative 0.002 0.006 0.0065
Onchocerca volvulus 0.0018 0.0046 0.0079
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0191 0.1084 0.1257
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.04 0.2333 0.2707
Entamoeba histolytica hypothetical protein 0.0036 0.0154 0.3759
Schistosoma mansoni opsin-like receptor 0.0049 0.0233 0.027
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0233 0.0233
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0012 0.0011 0.0019
Onchocerca volvulus 0.0049 0.0233 0.0396
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Onchocerca volvulus 0.0049 0.0233 0.0396
Loa Loa (eye worm) glutaminase 0.0546 0.3202 0.5458
Trypanosoma cruzi WLM domain containing protein, putative 0.0353 0.2048 0.8775
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0072 0.0371 0.0632
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Schistosoma mansoni hypothetical protein 0.0541 0.3178 0.3687
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0371 0.0596
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0049 0.0233 0.0233
Schistosoma mansoni hypothetical protein 0.0016 0.0033 0.0038
Brugia malayi RE15519p 0.0049 0.0233 0.0396
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.04 0.2333 1
Leishmania major protein kinase, putative,eukaryotic translation initiation factor 2-alpha kinase precursor, putative 0.0069 0.035 0.1489
Echinococcus multilocularis glycine receptor subunit beta 0.0058 0.0287 0.0287
Onchocerca volvulus 0.0012 0.0011 0.0019
Entamoeba histolytica hypothetical protein 0.0036 0.0154 0.3759
Schistosoma mansoni nAChR subunit 0.0012 0.0011 0.0013
Schistosoma mansoni rotamase 0.0035 0.0149 0.0172
Schistosoma mansoni nAChR subunit 0.0012 0.0011 0.0013
Echinococcus granulosus E3 ubiquitin protein ligase RNF146 0.0018 0.0046 0.0054
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.01 0.0132
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0233 0.027
Leishmania major hypothetical protein, conserved 0.0018 0.0046 0.0187
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.006 0.1086
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0049 0.0233 0.0396
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.0049 0.023 0.0355
Trichomonas vaginalis heat shock protein, putative 0.0034 0.0143 0.0206
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.01 0.0132
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0353 0.2048 0.8775
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0046 0.0187
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.01 0.0417
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0049 0.0233 0.027
Echinococcus multilocularis dro:myosuppressin receptor 0.0049 0.0233 0.0233
Echinococcus granulosus alpha 1A adrenergic receptor 0.0049 0.0233 0.027
Echinococcus granulosus E3 ubiquitin protein ligase Bre1 0.0018 0.0046 0.0054
Echinococcus multilocularis neuropeptide s receptor 0.0049 0.0233 0.0233
Schistosoma mansoni hypothetical protein 0.0049 0.0233 0.027
Schistosoma mansoni fusion 0.0353 0.2048 0.2376
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.0079
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.01 0.0132
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0233 0.0233
Schistosoma mansoni rnf5 0.0018 0.0046 0.0054
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0014 0.0023 0.0026
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0049 0.0233 0.0396
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0233 0.027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0233 0.027
Echinococcus multilocularis heat shock protein 90 0.0034 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Leishmania major hypothetical protein, conserved 0.0353 0.2048 0.8775
Echinococcus multilocularis muscleblind protein 1 0.0149 0.0829 0.0829
Plasmodium vivax hypothetical protein, conserved 0.0991 0.5867 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0049 0.0233 0.027
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0191 0.1084 0.1084
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0233 0.027
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0233 0.027
Loa Loa (eye worm) hypothetical protein 0.005 0.0236 0.0403
Leishmania major glycosyl hydrolase-like protein 0.0027 0.01 0.0417
Chlamydia trachomatis SWIB complex protein 0.0991 0.5867 0.5
Schistosoma mansoni adenoreceptor 0.0049 0.0233 0.027
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0027 0.0101 0.018
Brugia malayi hypothetical protein 0.0049 0.0233 0.0396
Echinococcus granulosus orexin receptor type 2 0.0049 0.0233 0.027
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0143 0.0601
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0233 0.027
Trichomonas vaginalis ankyrin, putative 0.0018 0.0046 0.0041
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0233 0.027
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Entamoeba histolytica zinc finger domain containing protein 0.0018 0.0046 0.0683
Brugia malayi Glycosyl hydrolases family 31 protein 0.0072 0.0371 0.0632
Schistosoma mansoni alpha-glucosidase 0.028 0.1613 0.1872
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0049 0.0233 0.0396
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0012 0.0011 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0233 0.027
Brugia malayi G protein-coupled receptor 0.0049 0.0233 0.0396
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0233 0.0233
Brugia malayi hypothetical protein 0.0018 0.0046 0.0079
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0233 0.027
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0154 0.0178
Brugia malayi Isocitrate dehydrogenase 0.04 0.2333 0.3977
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.0049 0.023 0.023
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.01 0.017
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger) containing protein, putative 0.0018 0.0046 0.0187
Plasmodium vivax trophozoite exported protein 1, putative 0.0018 0.0046 0.0041
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0144 0.0604
Echinococcus multilocularis zinc finger protein Ran binding 0.0353 0.2048 0.2048
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Echinococcus multilocularis sex peptide receptor 0.0049 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.0079
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0018 0.0046 0.0041
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0049 0.0233 0.0396
Brugia malayi Hypothetical RING finger protein C16C10.7 in chromosome III 0.0018 0.0046 0.0079
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Schistosoma mansoni mind bomb 0.0018 0.0046 0.0054
Echinococcus granulosus somatostatin receptor 0.0049 0.0233 0.027
Schistosoma mansoni myosin xvIII 0.0049 0.0233 0.027
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0058 0.0287 0.0333
Trypanosoma cruzi heat shock protein 90, putative 0.0034 0.0143 0.0601
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0233 0.0233
Schistosoma mansoni peter pan-related 0.0018 0.0046 0.0054
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Trypanosoma cruzi heat shock protein 85, putative 0.0027 0.0101 0.0423
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0018 0.0046 0.0041
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.04 0.2333 1
Brugia malayi ORL1-like opioid receptor 0.0049 0.0233 0.0396
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0027 0.0101 0.0118
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0012 0.0011 0.0019
Entamoeba histolytica tartrate dehydrogenase, putative 0.0049 0.023 0.5955
Echinococcus multilocularis muscleblind protein 0.0149 0.0829 0.0829
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0049 0.0233 0.027
Echinococcus granulosus sex peptide receptor 0.0049 0.0233 0.027
Brugia malayi G-protein coupled receptor 0.0049 0.0233 0.0396
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0233 0.0233
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0049 0.0233 0.0233
Echinococcus granulosus zinc finger protein Ran binding 0.0353 0.2048 0.2376
Toxoplasma gondii heat shock protein 75, putative 0.0014 0.0023 0.0034
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Loa Loa (eye worm) hypothetical protein 0.0049 0.023 0.0392
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0012 0.0011 0.0011
Trypanosoma brucei ring finger containing protein 0.0018 0.0046 0.0187
Loa Loa (eye worm) heat shock protein 75 0.0014 0.0023 0.0039
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Echinococcus multilocularis ring and YY1 binding protein 0.0353 0.2048 0.2048
Schistosoma mansoni amine GPCR 0.0049 0.0233 0.027
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0011 0.0019
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0226 0.0385
Echinococcus multilocularis somatostatin receptor 0.0049 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0341 0.0894
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.04 0.2333 0.3953
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Echinococcus multilocularis SWI:SNF matrix associated 0.0991 0.5867 0.5867
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0353 0.2048 0.3465
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0154 0.0178
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0226 0.0385
Echinococcus granulosus heat shock protein 90 0.0034 0.0143 0.0166
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0233 0.0396
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0058 0.0287 0.0333
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0353 0.2048 0.8775
Echinococcus granulosus glycine receptor subunit alpha 1 0.0058 0.0287 0.0333
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0011 0.0019
Echinococcus granulosus g protein coupled receptor 0.0049 0.0233 0.027
Toxoplasma gondii RING zinc finger protein 0.0018 0.0046 0.0074
Echinococcus granulosus Zinc finger RanBP2 type 0.0353 0.2048 0.2376
Onchocerca volvulus 0.0353 0.2048 0.349
Brugia malayi Cation transporter family protein 0.0012 0.0011 0.0019
Toxoplasma gondii heat shock protein HSP90 0.0034 0.0143 0.0239
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0236 0.0403
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0353 0.2048 0.3487
Echinococcus granulosus glycine receptor subunit alpha 1 0.0058 0.0287 0.0333
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0144 0.0604
Echinococcus multilocularis SWI:SNF matrix associated 0.0991 0.5867 0.5867
Schistosoma mansoni glutaminase 0.0546 0.3202 0.3715
Toxoplasma gondii hypothetical protein 0.0018 0.0046 0.0074
Onchocerca volvulus 0.0049 0.0233 0.0396
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0046 0.0187
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0223 0.0381
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0233 0.0233
Trypanosoma brucei Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0353 0.2048 0.8775
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.04 0.2333 0.2333
Toxoplasma gondii Bardet-Biedl syndrome 5, putative 0.0018 0.0046 0.0074
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0371 0.0596
Loa Loa (eye worm) hypothetical protein 0.0092 0.0492 0.0838
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Brugia malayi hypothetical protein 0.0151 0.0839 0.1431
Schistosoma mansoni alpha glucosidase 0.0072 0.0371 0.043
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0033 0.0038
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0143 0.0601
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0046 0.0187
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0012 0.0011 0.0013
Leishmania major hypothetical protein, conserved 0.0353 0.2048 0.8775
Trichomonas vaginalis maltase-glucoamylase, putative 0.0072 0.0371 0.0596
Plasmodium falciparum E3 ubiquitin-protein ligase RNF5, putative 0.0018 0.0046 0.0041
Schistosoma mansoni lozenge 0.0061 0.0305 0.0354
Loa Loa (eye worm) endoplasmin 0.0034 0.0143 0.0244
Trichomonas vaginalis sex-determining protein fem-1, putative 0.0018 0.0046 0.0041
Schistosoma mansoni neuropeptide receptor 0.0049 0.0233 0.027
Schistosoma mansoni biogenic amine receptor 0.0049 0.0233 0.027
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0012 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0233 0.027
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0371 0.0596
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0991 0.5867 1
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0353 0.2048 0.2376
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0353 0.2048 0.349
Entamoeba histolytica hypothetical protein 0.0036 0.0154 0.3759
Leishmania major hypothetical protein, conserved 0.0018 0.0046 0.0187
Echinococcus granulosus heat shock protein 0.0034 0.0143 0.0166
Echinococcus granulosus g protein coupled receptor 0.0049 0.0233 0.027
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0223 0.0259
Echinococcus granulosus heat shock protein 90 0.0027 0.0101 0.0118
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0058 0.0287 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Onchocerca volvulus 0.0048 0.0223 0.0381
Trypanosoma brucei heat shock protein, putative 0.0034 0.0143 0.0601
Schistosoma mansoni hypothetical protein 0.0049 0.0233 0.027
Schistosoma mansoni hypothetical protein 0.0016 0.0033 0.0038
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0012 0.0011 0.0019
Brugia malayi AKH receptor 0.0049 0.0233 0.0396
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0233 0.027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Mycobacterium leprae PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) 0.0049 0.023 1
Trypanosoma brucei DNA repair protein, putative 0.0018 0.0046 0.0187
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0263 0.0263
Schistosoma mansoni ap endonuclease 0.002 0.006 0.007
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0233 0.027
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.04 0.2333 0.2707
Loa Loa (eye worm) hypothetical protein 0.0488 0.2858 0.4872
Schistosoma mansoni neuropeptide receptor 0.0049 0.0233 0.027
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.006 0.0065
Plasmodium falciparum heat shock protein 90 0.0034 0.0143 0.0206
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Schistosoma mansoni alpha-1 adrenergic receptor 0.0049 0.0233 0.027
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0233 0.027
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Echinococcus granulosus serotonin receptor 0.0049 0.0233 0.027
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0233 0.0396
Brugia malayi mbt repeat family protein 0.0048 0.0223 0.0381
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Echinococcus multilocularis G-protein coupled receptor, putative 0.0049 0.0233 0.0233
Plasmodium vivax RING zinc finger protein, putative 0.0018 0.0046 0.0041
Toxoplasma gondii heat shock protein 90, putative 0.0034 0.0143 0.0239
Entamoeba histolytica zinc finger domain containing protein 0.0018 0.0046 0.0683
Plasmodium falciparum trophozoite exported protein 1 0.0018 0.0046 0.0041
Plasmodium falciparum RING zinc finger protein, putative 0.0018 0.0046 0.0041
Echinococcus multilocularis ring finger protein 113a 0.0018 0.0047 0.0047
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0027 0.0101 0.4342
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.0049 0.023 0.0392
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0233 0.027
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0143 0.0601
Echinococcus granulosus GPCR family 2 0.0016 0.0033 0.0038
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0049 0.0233 0.0396
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0226 0.0226
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0149 0.0253
Loa Loa (eye worm) brahma associated protein 0.0991 0.5867 1
Leishmania major hypothetical protein, conserved 0.0018 0.0046 0.0187
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Trypanosoma brucei heat shock protein, putative 0.0034 0.0143 0.0601
Schistosoma mansoni neuropeptide f receptor 76f 0.0049 0.0233 0.027
Echinococcus granulosus isocitrate dehydrogenase NAD 0.0049 0.023 0.0267
Schistosoma mansoni hypothetical protein 0.0991 0.5867 0.6806
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0012 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0011 0.0019
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.04 0.2333 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0027 0.01 0.017
Giardia lamblia Ser/Thr protein kinase 0.0018 0.0046 0.0000011438
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.04 0.2333 0.2333
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0018 0.0046 0.0074
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0233 0.0233
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0233 0.0233
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0236 0.0403
Giardia lamblia Heat shock protein HSP 90-alpha 0.0027 0.0101 0.5699
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0101 0.0135
Brugia malayi hypothetical protein 0.0049 0.0233 0.0396
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0033 0.0038
Brugia malayi G-protein coupled receptor 0.0049 0.0233 0.0396
Echinococcus granulosus 7tm_1 domain containing protein 0.0049 0.0233 0.027
Loa Loa (eye worm) hypothetical protein 0.0353 0.2048 0.349
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0341 0.0894
Echinococcus multilocularis heat shock protein 0.0034 0.0143 0.0143
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0058 0.0287 0.0333
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Trypanosoma cruzi Eukaryotic translation initiation factor 2-alpha kinase 2 0.0069 0.035 0.1489
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0991 0.5867 0.5867
Schistosoma mansoni alpha-glucosidase 0.028 0.1613 0.1872
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0018 0.0046 0.0074
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0263 0.0305
Brugia malayi excitatory GABA receptor EXP-1A 0.0012 0.0011 0.0019
Schistosoma mansoni amine GPCR 0.0049 0.0233 0.027
Brugia malayi Neuralized family protein 0.0018 0.0046 0.0079
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.0049 0.023 0.0267
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0012 0.0011 0.0013
Brugia malayi Zinc finger protein 183 homolog 0.0018 0.0047 0.008
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0341 0.0577
Onchocerca volvulus Protein neuralized homolog 0.0018 0.0046 0.0079
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0049 0.0233 0.0233
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Schistosoma mansoni heat shock protein 0.0034 0.0143 0.0166
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0053 0.0254 0.0432
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0049 0.0233 0.027
Brugia malayi hypothetical protein 0.0049 0.0233 0.0396
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.04 0.2333 0.3953
Leishmania major hypothetical protein, conserved 0.0353 0.2048 0.8775
Schistosoma mansoni endoplasmin 0.0034 0.0143 0.0166
Trypanosoma cruzi hypothetical protein 0.0018 0.0046 0.0187
Brugia malayi Dopamine receptor protein 2 0.0049 0.0233 0.0396
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0012 0.0011 0.0019
Schistosoma mansoni unc-13 (munc13) 0.0049 0.023 0.0267
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Leishmania major hypothetical protein 0.0018 0.0046 0.0187
Onchocerca volvulus 0.0012 0.0011 0.0019
Brugia malayi hypothetical protein 0.0049 0.0233 0.0396
Schistosoma mansoni hypothetical protein 0.0541 0.3178 0.3687
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Echinococcus granulosus g protein coupled receptor 0.0049 0.0233 0.027
Brugia malayi larval opioid receptor 0.0049 0.0233 0.0396
Schistosoma mansoni eyes absent homolog 0.0092 0.0492 0.057
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Schistosoma mansoni amine GPCR 0.0049 0.0233 0.027
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0018 0.0046 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0069 0.035 0.056
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.0049 0.023 0.0267
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Toxoplasma gondii hypothetical protein 0.0018 0.0046 0.0074
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0101 0.0135
Echinococcus granulosus 7TM GPCR rhodopsin 0.0049 0.0233 0.027
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0341 0.0396
Leishmania major hypothetical protein, conserved 0.0018 0.0046 0.0187
Echinococcus granulosus g-protein coupled receptor 0.0049 0.0233 0.027
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0052 0.0248 0.0288
Echinococcus multilocularis Protein lozenge 0.0061 0.0305 0.0305
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.01 0.0132
Loa Loa (eye worm) RiNg Finger protein family member 0.0018 0.0047 0.008
Onchocerca volvulus 0.0049 0.0233 0.0396
Onchocerca volvulus RING finger protein 141 homolog 0.0018 0.0046 0.0079
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0012 0.0011 0.0019
Echinococcus granulosus neutral alpha glucosidase AB 0.0072 0.0371 0.043
Brugia malayi putative neuropeptide receptor 0.0049 0.0233 0.0396
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0353 0.2048 0.349
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0072 0.0371 0.0596
Trypanosoma cruzi heat shock protein, putative 0.0014 0.0023 0.0085
Onchocerca volvulus 0.0049 0.0233 0.0396
Echinococcus granulosus survival motor neuron protein 1 0.0505 0.2962 0.3436
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0233 0.027
Schistosoma mansoni histamine h1 receptor 0.0049 0.0233 0.027
Onchocerca volvulus 0.0151 0.0839 0.1431
Trypanosoma brucei glucosidase, putative 0.0072 0.0371 0.1579
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0991 0.5867 1
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0223 0.0259
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0233 0.027
Entamoeba histolytica zinc finger domain containing protein 0.0018 0.0046 0.0683
Brugia malayi brahma associated protein 60 kDa 0.0991 0.5867 1
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0233 0.0233
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0144 0.3476
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0991 0.5867 1
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0012 0.0011 0.0019
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0991 0.5867 1
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0371 0.1579
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0033 0.0056
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0233 0.0233
Brugia malayi hypothetical protein 0.0036 0.0154 0.0262
Echinococcus multilocularis neuropeptide FF receptor 2 0.0049 0.0233 0.0233
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0226 0.0262
Onchocerca volvulus 0.0012 0.0011 0.0019
Brugia malayi SWIB/MDM2 domain containing protein 0.0991 0.5867 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0018 0.0046 0.0041
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0226 0.0262
Brugia malayi isocitrate dehydrogenase 0.04 0.2333 0.3977
Brugia malayi YY1-associated factor 2 0.0353 0.2048 0.349
Loa Loa (eye worm) hypothetical protein 0.0053 0.0254 0.0432
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0072 0.0371 1
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0012 0.0011 0.0013
Trypanosoma brucei heat shock protein, putative 0.0034 0.0143 0.0601
Entamoeba histolytica zinc finger domain containing protein 0.0018 0.0046 0.0683
Loa Loa (eye worm) hypothetical protein 0.0027 0.01 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0048 0.0056
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Onchocerca volvulus 0.0991 0.5867 1
Entamoeba histolytica SPRY domain protein 0.0018 0.0046 0.0683
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0233 0.027
Mycobacterium ulcerans 3-isopropylmalate dehydrogenase 0.0049 0.023 0.0539
Echinococcus multilocularis E3 ubiquitin protein ligase LRSAM1 0.0018 0.0046 0.0046
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Trypanosoma cruzi WLM domain containing protein, putative 0.0353 0.2048 0.8775
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0143 0.0601
Trichomonas vaginalis sucrase-isomaltase, putative 0.0072 0.0371 0.0596
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Brugia malayi hypothetical protein 0.0505 0.2962 0.5048
Mycobacterium ulcerans glutaminase 0.0546 0.3202 1
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0012 0.0011 0.0013
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0233 0.027
Onchocerca volvulus 0.0049 0.0233 0.0396
Schistosoma mansoni hypothetical protein 0.0018 0.0046 0.0054
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0142 0.0242
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Leishmania major hypothetical protein, conserved 0.0353 0.2048 0.8775
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0226 0.0262
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Giardia lamblia Protein 21.1 0.0018 0.0046 0.0000011438
Loa Loa (eye worm) glutaminase 2 0.0546 0.3202 0.5458
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0012 0.0011 0.0011
Trypanosoma cruzi Heat shock protein 83, putative 0.0034 0.0143 0.0601
Brugia malayi hypothetical protein 0.0049 0.0233 0.0396
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.0079
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0223 0.0223
Brugia malayi neuropeptide F receptor 0.0049 0.0233 0.0396
Schistosoma mansoni opsin-like receptor 0.0049 0.0233 0.027
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0353 0.2048 0.8775
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0233 0.027
Giardia lamblia Heat shock protein HSP 90-alpha 0.0034 0.0143 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.01 0.0132
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0223 0.0259
Loa Loa (eye worm) runx1 0.0061 0.0305 0.052
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Trypanosoma cruzi hypothetical protein, conserved 0.0353 0.2048 0.8775
Echinococcus multilocularis microtubule associated protein 2 0.1451 0.862 0.862
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0058 0.0287 0.0333
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0353 0.2048 0.8775
Loa Loa (eye worm) hypothetical protein 0.0048 0.0223 0.0381
Trypanosoma brucei hypothetical protein, conserved 0.0353 0.2048 0.8775
Leishmania major hypothetical protein, conserved 0.0018 0.0046 0.0187
Giardia lamblia Kinase, NEK 0.0018 0.0048 0.019
Leishmania major hypothetical protein, conserved 0.0018 0.0046 0.0187
Echinococcus multilocularis lysosomal alpha glucosidase 0.0325 0.1884 0.1884
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0046 0.0187
Brugia malayi hypothetical protein 0.0049 0.0233 0.0396
Echinococcus granulosus lysosomal alpha glucosidase 0.0325 0.1884 0.2186
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0011 0.0019
Schistosoma mansoni brg-1 associated factor 0.0991 0.5867 0.6806
Echinococcus multilocularis E3 ubiquitin protein ligase MYLIP 0.0018 0.0046 0.0046
Onchocerca volvulus 0.0018 0.0046 0.0079
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0233 0.027
Schistosoma mansoni hypothetical protein 0.0293 0.1691 0.1962
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601
Echinococcus multilocularis E3 ubiquitin protein ligase Bre1 0.0018 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Onchocerca volvulus 0.0049 0.0233 0.0396
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0233 0.0233
Echinococcus granulosus ring and YY1 binding protein 0.0353 0.2048 0.2376
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.0079
Onchocerca volvulus 0.0049 0.0233 0.0396
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0012 0.0011 0.0011
Echinococcus multilocularis g-protein coupled receptor 0.0049 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Onchocerca volvulus 0.0353 0.2048 0.349
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0226 0.0262
Onchocerca volvulus 0.0488 0.2858 0.4872
Schistosoma mansoni RNA binding protein 0.0353 0.2048 0.2376
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0064 0.0071
Trypanosoma cruzi hypothetical protein 0.0018 0.0046 0.0187
Echinococcus granulosus fmrfamide receptor 0.0049 0.0233 0.027
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0341 0.0396
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0233 0.0233
Schistosoma mansoni opsin-like receptor 0.0049 0.0233 0.027
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Brugia malayi RING finger protein 20 0.0018 0.0046 0.0079
Echinococcus granulosus microtubule associated protein 2 0.1451 0.862 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0011 0.0019
Toxoplasma gondii isocitrate dehydrogenase 0.04 0.2333 0.3974
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.0079
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0012 0.0011 0.0013
Toxoplasma gondii helicase, putative 0.0018 0.0046 0.0074
Trypanosoma brucei heat shock protein, putative 0.0034 0.0143 0.0601
Echinococcus multilocularis lysosomal alpha glucosidase 0.0325 0.1884 0.1884
Mycobacterium tuberculosis Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.0049 0.023 0.0746
Leishmania major heat shock protein, putative 0.0014 0.0023 0.0085
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0396
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0233 0.027
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0052 0.0248 0.0423
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0226 0.0226
Schistosoma mansoni hypothetical protein 0.0991 0.5867 0.6806
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0341 0.0341
Onchocerca volvulus Neuropeptide F receptor homolog 0.0049 0.0233 0.0396
Schistosoma mansoni hypothetical protein 0.0036 0.0154 0.0178
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0046 0.0187
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.006 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0046 0.0041
Leishmania major heat shock protein 83-1 0.0034 0.0143 0.0601

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.345 uM Inhibition of Platelet-derived growth factor receptor ChEMBL. 12941342

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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