Detailed information for compound 982841

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 470.512 | Formula: C26H30O8
  • H donors: 4 H acceptors: 7 LogP: 4.47 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(=O)C1=C(O)C(C(=C(C1=O)Cc1c(O)c2C=CC(Oc2c(c1O)C(=O)CC)(C)C)O)(C)C
  • InChi: 1S/C26H30O8/c1-7-15(27)17-20(30)13(19(29)12-9-10-25(3,4)34-22(12)17)11-14-21(31)18(16(28)8-2)24(33)26(5,6)23(14)32/h9-10,29-30,32-33H,7-8,11H2,1-6H3
  • InChiKey: KFOIHZFXWKXAHE-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0091 0.085 0.1305
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0163 0.1484
Brugia malayi Cathepsin L-like cysteine proteinase 0.0064 0.0558 0.1126
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0024 0.0129 0.0537
Echinococcus granulosus expressed conserved protein 0.0107 0.1022 0.2644
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.136 1
Echinococcus multilocularis geminin 0.0195 0.1984 0.194
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0163 0.0329
Plasmodium falciparum serine repeat antigen 5 0.0024 0.0129 0.1515
Brugia malayi cathepsin F-like cysteine proteinase 0.0024 0.0129 0.026
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0163 0.1197
Plasmodium falciparum cysteine proteinase falcipain 1 0.0051 0.0421 0.4955
Onchocerca volvulus 0.0091 0.085 0.1305
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0136 0.0081
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0311 0.2285
Plasmodium falciparum serine repeat antigen 9 0.0024 0.0129 0.1515
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0163 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0086 0.08 0.2154
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0163 0.0329
Echinococcus multilocularis zinc finger protein 0.0022 0.01 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0024 0.0129 0.0228
Schistosoma mansoni cathepsin S (C01 family) 0.0024 0.0129 0.0347
Entamoeba histolytica cysteine proteinase, putative 0.0091 0.085 0.775
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0111 0.1067 0.3203
Echinococcus multilocularis cathepsin b 0.0319 0.3332 0.3295
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0163 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.085 0.1503
Echinococcus multilocularis calpain 0.0041 0.0311 0.0257
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0067 0.0596 0.1606
Loa Loa (eye worm) hypothetical protein 0.0024 0.0129 0.026
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.058 0.1435
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0177
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.136 1
Loa Loa (eye worm) fibroinase 0.0091 0.085 0.1716
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0311 0.0932
Schistosoma mansoni cathepsin F (C01 family) 0.0091 0.085 0.2289
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0311 0.2285
Trichomonas vaginalis importin beta-1, putative 0.0027 0.0159 0.028
Loa Loa (eye worm) hypothetical protein 0.0064 0.0558 0.1126
Giardia lamblia Cathepsin B precursor 0.0116 0.1119 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0024 0.0129 0.0347
Trypanosoma cruzi major cysteine proteinase, putative 0.0024 0.0129 0.0386
Loa Loa (eye worm) hypothetical protein 0.0064 0.0558 0.1126
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0024 0.0129 0.1174
Loa Loa (eye worm) hypothetical protein 0.0042 0.0325 0.0656
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0311 0.2285
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0227 0.1668
Mycobacterium ulcerans hypothetical protein 0.0027 0.0163 1
Brugia malayi Pre-SET motif family protein 0.0469 0.4954 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0091 0.085 0.2173
Plasmodium falciparum serine repeat antigen 2 0.0024 0.0129 0.1515
Entamoeba histolytica cysteine protease, putative 0.0051 0.0421 0.384
Schistosoma mansoni calpain-7 (C02 family) 0.0041 0.0311 0.0837
Brugia malayi PHD-finger family protein 0.0027 0.0164 0.0331
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0116 0.1119 0.1979
Echinococcus multilocularis muscleblind protein 0.0172 0.1733 0.1688
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0103 0.0985 0.2652
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0129 0.0228
Plasmodium falciparum serine repeat antigen 6 0.0024 0.0129 0.1515
Brugia malayi cathepsin Z-like cysteine proteinase 0.0024 0.0129 0.026
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0117 0.1133 0.3051
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0316 0.0263
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.136 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0067 0.0596 0.1606
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0462 0.0933
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.085 0.1503
Plasmodium falciparum serine repeat antigen 8 0.0024 0.0129 0.1515
Loa Loa (eye worm) hypothetical protein 0.0024 0.0129 0.026
Loa Loa (eye worm) hypothetical protein 0.0027 0.0159 0.0321
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.007 0.0015
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0163 0.5
Trypanosoma brucei kinesin, putative 0.0029 0.0177 0.1303
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0421 0.085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.085 0.1503
Leishmania major cysteine peptidase A (CPA) 0.0091 0.085 0.6252
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0064 0.0558 0.0986
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0136 0.0366
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.085 0.1503
Schistosoma mansoni hypothetical protein 0.0195 0.1984 0.5343
Entamoeba histolytica cysteine proteinase, putative 0.0064 0.0558 0.5084
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0024 0.0129 0.0228
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0421 0.0744
Plasmodium falciparum serine repeat antigen 7 0.0024 0.0129 0.1515
Brugia malayi cathepsin F-like cysteine proteinase 0.0027 0.0159 0.0321
Loa Loa (eye worm) hypothetical protein 0.0172 0.1733 0.3499
Echinococcus granulosus cysteine protease 0.0051 0.0421 0.1001
Echinococcus multilocularis expressed conserved protein 0.0107 0.1022 0.0973
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0129 0.0228
Brugia malayi fibroinase precursor 0.0024 0.0129 0.026
Echinococcus multilocularis calpain 5 0.0041 0.0311 0.0257
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.136 0.408
Loa Loa (eye worm) hypothetical protein 0.0049 0.0394 0.0796
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.085 0.1503
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.085 0.1503
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0024 0.0129 0.026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0129 0.0228
Echinococcus multilocularis calpain A 0.0117 0.1135 0.1086
Schistosoma mansoni bromodomain containing protein 0.007 0.0623 0.1676
Echinococcus granulosus calpain 0.0041 0.0311 0.0699
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0088 0.139
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0311 0.0932
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0103 0.0985 0.2652
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0355 0.3713 0.7496
Entamoeba histolytica hypothetical protein 0.0041 0.0316 0.2882
Plasmodium vivax unspecified product 0.0051 0.0421 0.4373
Loa Loa (eye worm) ctsf protein 0.0091 0.085 0.1716
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0024 0.0129 0.0347
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0129 0.0228
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0311 0.2285
Echinococcus multilocularis survival motor neuron protein 1 0.0272 0.2822 0.2782
Plasmodium vivax vivapain-2 0.0091 0.085 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0071 0.0638 0.1916
Schistosoma mansoni hypothetical protein 0.0047 0.0375 0.1011
Loa Loa (eye worm) MH2 domain-containing protein 0.0138 0.1358 0.2742
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.085 0.1503
Onchocerca volvulus 0.0056 0.0469 0.0616
Echinococcus granulosus cathepsin b 0.0319 0.3332 0.8958
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0024 0.0129 0.0537
Brugia malayi Cathepsin L-like precursor 0.0064 0.0558 0.1126
Echinococcus granulosus geminin 0.0195 0.1984 0.5273
Loa Loa (eye worm) hypothetical protein 0.0024 0.0129 0.026
Schistosoma mansoni hypothetical protein 0.0017 0.0049 0.0133
Echinococcus multilocularis cathepsin b 0.0319 0.3332 0.3295
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0129 0.0228
Entamoeba histolytica hypothetical protein 0.0041 0.0316 0.2882
Echinococcus multilocularis Niemann Pick C1 protein 0.0162 0.1625 0.1579
Entamoeba histolytica cysteine protease, putative 0.0091 0.085 0.775
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0177
Brugia malayi Cathepsin L-like precursor 0.0064 0.0558 0.1126
Leishmania major cathepsin L-like protease 0.0138 0.136 1
Brugia malayi Papain family cysteine protease containing protein 0.0024 0.0129 0.026
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0117 0.1133 0.1084
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0091 0.085 0.1716
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0103 0.0985 0.1988
Echinococcus multilocularis sterol regulatory element binding protein 0.0049 0.0394 0.0341
Loa Loa (eye worm) hypothetical protein 0.0109 0.1044 0.2107
Onchocerca volvulus 0.0091 0.085 0.1305
Trypanosoma cruzi ISWI complex protein 0.0017 0.0049 0.0148
Loa Loa (eye worm) hypothetical protein 0.006 0.0513 0.1036
Leishmania major cathepsin L-like protease 0.0091 0.085 0.6252
Echinococcus granulosus calpain A 0.0117 0.1135 0.2953
Loa Loa (eye worm) hypothetical protein 0.0027 0.0163 0.0329
Schistosoma mansoni hypothetical protein 0.0017 0.0055 0.0148
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0319 0.3332 0.8973
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0421 0.3098
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0311 0.2285
Loa Loa (eye worm) calpain 0.0041 0.0311 0.0627
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0051 0.0421 0.1264
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0116 0.1119 0.8234
Loa Loa (eye worm) hypothetical protein 0.0113 0.1097 0.2214
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0055 0.0111
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0091 0.085 0.0799
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0136 0.0221
Brugia malayi Papain family cysteine protease containing protein 0.0024 0.0129 0.026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.136 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0469 0.0947
Brugia malayi calpain family protein 1 0.0109 0.1044 0.2107
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0103 0.0985 0.1988
Loa Loa (eye worm) hypothetical protein 0.0319 0.3332 0.6726
Brugia malayi calpain 5 0.0029 0.0177 0.0358
Loa Loa (eye worm) hypothetical protein 0.0096 0.091 0.1838
Schistosoma mansoni survival motor neuron protein 0.0056 0.0469 0.1264
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0129 0.0228
Entamoeba histolytica cysteine protease, putative 0.0024 0.0129 0.1174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.085 0.1503
Entamoeba histolytica cysteine protease, putative 0.0024 0.0129 0.1174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.136 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0296 0.0242
Schistosoma mansoni cathepsin B (C01 family) 0.0024 0.0129 0.0347
Loa Loa (eye worm) hypothetical protein 0.0068 0.06 0.1211
Echinococcus granulosus cathepsin L 0.0051 0.0421 0.1001
Schistosoma mansoni cathepsin F (C01 family) 0.0064 0.0558 0.1502
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0319 0.3332 0.8973
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0311 0.0932
Plasmodium falciparum cysteine proteinase falcipain 3 0.0091 0.085 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0091 0.085 0.1503
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0115 0.1116 0.3005
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0109 0.1044 0.2812
Trypanosoma brucei antigen, putative 0.0041 0.0311 0.2285
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.085 0.1503
Echinococcus multilocularis cathepsin L cysteine protease 0.0091 0.085 0.0799
Echinococcus granulosus calpain A 0.0041 0.0311 0.0699
Entamoeba histolytica cysteine protease, putative 0.0051 0.0421 0.384
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0163 0.1484
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0088 0.5
Echinococcus granulosus cathepsin b 0.0319 0.3332 0.8958
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0117 0.1133 0.3051
Loa Loa (eye worm) hypothetical protein 0.0272 0.2822 0.5696
Leishmania major hypothetical protein, conserved 0.0017 0.0049 0.0362
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0421 0.384
Entamoeba histolytica cysteine protease, putative 0.0051 0.0421 0.384
Echinococcus granulosus histone lysine methyltransferase setb 0.0086 0.08 0.2036
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0055 0.0111
Onchocerca volvulus 0.0091 0.085 0.1305
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0117 0.1133 0.2947
Giardia lamblia Cathepsin B precursor 0.0116 0.1119 1
Entamoeba histolytica cysteine protease, putative 0.0024 0.0129 0.1174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.136 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.007 0.0189
Echinococcus granulosus calpain 7 C02 family 0.0041 0.0311 0.0699
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.007 0.0189
Echinococcus multilocularis calpain family protein 1, d 0.008 0.0733 0.0682
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.085 0.1503
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.136 1
Plasmodium vivax serine-repeat antigen (SERA) 0.0024 0.0129 0.0537
Echinococcus granulosus cathepsin l1 0.0064 0.0558 0.1374
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0024 0.0129 0.0228
Brugia malayi Cathepsin L-like precursor 0.0091 0.085 0.1716
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0113 0.0228
Plasmodium vivax importin-beta 2, putative 0.0033 0.0227 0.1823
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0163 1
Echinococcus granulosus Niemann Pick C1 protein 0.0113 0.1097 0.2848
Schistosoma mansoni hypothetical protein 0.0047 0.0375 0.1011
Brugia malayi cathepsin L-like precursor 0.0064 0.0558 0.1126
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0103 0.0985 0.2652
Loa Loa (eye worm) hypothetical protein 0.0064 0.0558 0.1126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.136 1
Leishmania major cathepsin L-like protease 0.0138 0.136 1
Entamoeba histolytica cysteine protease, putative 0.0051 0.0421 0.384
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0041 0.0311 0.0932
Loa Loa (eye worm) calpain family protein 1 0.008 0.0733 0.148
Echinococcus granulosus muscleblind protein 0.0172 0.1733 0.4588
Brugia malayi cathepsin L-like cysteine proteinase 0.0024 0.0129 0.026
Loa Loa (eye worm) hypothetical protein 0.0055 0.0462 0.0933
Trypanosoma cruzi cruzipain precursor, putative 0.0027 0.0159 0.0477
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0316 0.0851
Toxoplasma gondii cathepsin CPL 0.0091 0.085 0.7593
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0024 0.0129 0.0347
Entamoeba histolytica cysteine protease, putative 0.0051 0.0421 0.384
Brugia malayi Niemann-Pick C1 protein precursor 0.0113 0.1097 0.2214
Entamoeba histolytica cysteine protease, putative 0.0051 0.0421 0.384
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.085 0.1503
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0163 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0163 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0024 0.0129 0.0347
Leishmania major cathepsin L-like protease 0.0138 0.136 1
Loa Loa (eye worm) calpain family protein 1 0.0109 0.1044 0.2107
Onchocerca volvulus 0.0064 0.0558 0.0776
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0311 0.0932
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0024 0.0129 0.0537
Plasmodium vivax unspecified product 0.0024 0.0129 0.0537
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0067 0.0596 0.0544
Onchocerca volvulus 0.0091 0.085 0.1305
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0078 0.0157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0129 0.0228
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.085 0.1503
Schistosoma mansoni cathepsin s 0.0027 0.0159 0.0428
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0024 0.0129 0.1174
Brugia malayi Bromodomain containing protein 0.0042 0.0324 0.0654
Echinococcus multilocularis cathepsin L 0.0024 0.0129 0.0074
Schistosoma mansoni calpain (C02 family) 0.0041 0.0311 0.0837
Onchocerca volvulus Cathepsin L homolog 0.0091 0.085 0.1305
Leishmania major cathepsin L-like protease 0.0091 0.085 0.6252
Loa Loa (eye worm) hypothetical protein 0.008 0.0733 0.148
Loa Loa (eye worm) hypothetical protein 0.0024 0.0129 0.026
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0163 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0113 0.1097 0.1048
Brugia malayi calpain family protein 1 0.0109 0.1044 0.2107
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.0159 0.0476
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0091 0.085 0.0799
Loa Loa (eye worm) hypothetical protein 0.0027 0.0159 0.0321
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0116 0.1119 0.336
Plasmodium vivax unspecified product 0.0027 0.0159 0.0932
Schistosoma mansoni importin beta-1 0.0033 0.0227 0.0611
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0163 1
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0024 0.0129 0.1515
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.085 0.1503
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.136 0.408
Schistosoma mansoni patched 1 0.0049 0.0394 0.1062
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0091 0.085 1
Entamoeba histolytica cysteine protease, putative 0.0051 0.0421 0.384
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0103 0.0985 0.2541
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0319 0.3332 1
Entamoeba histolytica cysteine protease, putative 0.0024 0.0129 0.1174
Schistosoma mansoni hypothetical protein 0.0056 0.0469 0.1264
Echinococcus granulosus survival motor neuron protein 1 0.0272 0.2822 0.7563
Echinococcus granulosus calpain 5 0.0041 0.0311 0.0699
Entamoeba histolytica protein kinase, putative 0.0029 0.0177 0.1615
Entamoeba histolytica cysteine protease, putative 0.0024 0.0129 0.1174
Echinococcus multilocularis hypothetical protein 0.0041 0.0311 0.0257
Toxoplasma gondii cathepsin CPC1 0.0024 0.0129 0.115
Toxoplasma gondii cathepsin CPC2 0.0024 0.0129 0.115
Trypanosoma cruzi cysteine protease, putative 0.0051 0.0421 0.1264
Leishmania major cathepsin L-like protease 0.0091 0.085 0.6252
Loa Loa (eye worm) hypothetical protein 0.0091 0.085 0.1716
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.085 0.1503
Entamoeba histolytica hypothetical protein 0.0041 0.0316 0.2882
Echinococcus multilocularis cathepsin L cysteine protease 0.0091 0.085 0.0799
Loa Loa (eye worm) cysteine protease 0.0091 0.085 0.1716
Echinococcus granulosus sterol regulatory element binding protein 0.0049 0.0394 0.0928
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0065 0.0569 0.1406
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0024 0.0129 0.0537
Loa Loa (eye worm) hypothetical protein 0.0078 0.0711 0.1436
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0163 0.0329
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0024 0.0129 0.1515
Schistosoma mansoni hypothetical protein 0.0023 0.0113 0.0304
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0311 0.0932
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0394 0.0697
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0051 0.0421 0.1134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0129 0.0228
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0163 0.1484
Entamoeba histolytica cysteine protease, putative 0.0051 0.0421 0.384
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0064 0.0558 0.0986
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0024 0.0129 0.0347
Brugia malayi Cathepsin L-like precursor 0.0091 0.085 0.1716
Brugia malayi Papain family cysteine protease containing protein 0.0024 0.0129 0.026
Plasmodium falciparum serine repeat antigen 4 0.0024 0.0129 0.1515
Brugia malayi calpain 7 0.0041 0.0311 0.0627
Loa Loa (eye worm) hypothetical protein 0.0045 0.0353 0.0713
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.136 0.408
Trypanosoma cruzi cysteine proteinase, putative 0.0051 0.0421 0.1264
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0024 0.0129 0.0228
Trypanosoma cruzi kinesin, putative 0.0029 0.0177 0.0532
Leishmania major kinesin, putative 0.0029 0.0177 0.1303
Plasmodium falciparum importin beta, putative 0.0033 0.0227 0.2668
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.085 0.1503
Plasmodium falciparum serine repeat antigen 3 0.0024 0.0129 0.1515
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0024 0.0129 0.0228
Echinococcus granulosus Niemann Pick C1 protein 0.0162 0.1625 0.4291
Schistosoma mansoni hypothetical protein 0.0017 0.0055 0.0148
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0055 0.0111
Entamoeba histolytica cysteine protease, putative 0.0024 0.0129 0.1174
Echinococcus multilocularis protein patched 0.0049 0.0394 0.0341
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0296 0.0658
Brugia malayi Cathepsin L-like precursor 0.0027 0.0159 0.0321
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0421 0.1264
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0086 0.08 0.2154
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0319 0.3332 0.8973
Schistosoma mansoni Mername-AA248 (C02 family) 0.0041 0.0311 0.0837
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.058 0.0528
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0067 0.0596 0.5326
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.085 0.1503
Brugia malayi RNA, U transporter 1 0.0094 0.0891 0.1799
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0163 0.1197
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0024 0.0129 0.0228
Trypanosoma cruzi kinesin, putative 0.0029 0.0177 0.0532
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0311 0.0932
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0024 0.0129 0.0537
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0024 0.0129 0.026
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0024 0.0129 0.0537
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0177
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0024 0.0129 0.0537
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0177
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0311 0.0932
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0163 0.1197
Plasmodium falciparum serine repeat antigen 1 0.0024 0.0129 0.1515
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0041 0.0311 0.2285
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0027 0.0159 0.0321
Entamoeba histolytica cysteine protease, putative 0.0051 0.0421 0.384
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0227 0.1668
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0177
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0129 0.0228
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0311 0.2285
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.085 0.1503
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0024 0.0129 0.026
Brugia malayi Cathepsin L-like precursor 0.0091 0.085 0.1716
Leishmania major importin beta-1 subunit, putative 0.0027 0.0159 0.1167
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0129 0.0228
Onchocerca volvulus 0.0068 0.06 0.0852
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.007 0.0042
Loa Loa (eye worm) transcription factor SMAD2 0.0138 0.1358 0.2742
Echinococcus granulosus zinc finger protein 0.0022 0.01 0.0124
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0274 0.0552
Loa Loa (eye worm) hypothetical protein 0.0047 0.0376 0.0759
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0103 0.0985 0.0935
Brugia malayi Cathepsin L-like precursor 0.0091 0.085 0.1716
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0091 0.085 0.1716
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0024 0.0129 0.0347
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0469 0.4954 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0024 0.0129 0.0228
Brugia malayi Papain family cysteine protease containing protein 0.0091 0.085 0.1716
Loa Loa (eye worm) hypothetical protein 0.0027 0.0163 0.0329
Entamoeba histolytica hypothetical protein 0.0041 0.0316 0.2882
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0103 0.0985 0.0935
Schistosoma mansoni hypothetical protein 0.0195 0.1984 0.5343
Brugia malayi MH2 domain containing protein 0.0138 0.1358 0.2742
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0159 0.028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0129 0.0228
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0311 0.0932
Plasmodium vivax SET domain protein, putative 0.0067 0.0596 0.667
Onchocerca volvulus Cathepsin F homolog 0.0091 0.085 0.1305
Plasmodium vivax vivapain-1 0.0051 0.0421 0.4373
Schistosoma mansoni hypothetical protein 0.0047 0.0375 0.1011
Schistosoma mansoni hypothetical protein 0.0017 0.0055 0.0148
Trypanosoma cruzi cruzipain precursor, putative 0.0138 0.136 0.408
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0024 0.0129 0.0537
Plasmodium vivax vivapain-3 0.0051 0.0421 0.4373
Entamoeba histolytica calpain large subunit domain III containing protein 0.0029 0.0177 0.1615
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0421 0.0744
Echinococcus multilocularis calpain 7 (C02 family) 0.0041 0.0311 0.0257
Plasmodium vivax vivapain-2 0.0091 0.085 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0129 0.026
Schistosoma mansoni zinc finger protein 0.0022 0.01 0.027
Trypanosoma cruzi cysteine peptidase, putative 0.0091 0.085 0.2551
Entamoeba histolytica hypothetical protein 0.0027 0.0159 0.1447
Echinococcus granulosus cathepsin l cysteine peptidase 0.0091 0.085 0.2173
Loa Loa (eye worm) hypothetical protein 0.0086 0.08 0.1615
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0421 0.085
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0311 0.0932
Loa Loa (eye worm) hypothetical protein 0.0017 0.0055 0.0111
Echinococcus multilocularis protein dispatched 1 0.0056 0.0469 0.0416
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0024 0.0129 0.1515
Onchocerca volvulus 0.0027 0.0163 0.0062
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0311 0.2285
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0091 0.085 0.1503
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0051 0.0421 0.1134
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0086 0.08 0.0749
Brugia malayi hypothetical protein 0.0041 0.0316 0.0638
Brugia malayi cathepsin Z-like cysteine proteinase 0.0024 0.0129 0.026
Brugia malayi hypothetical protein 0.0272 0.2822 0.5696
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.085 0.1503
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0024 0.0129 0.0228
Loa Loa (eye worm) hypothetical protein 0.0038 0.0274 0.0552
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0024 0.0129 0.0347
Brugia malayi Muscleblind-like protein 0.0172 0.1733 0.3499
Onchocerca volvulus 0.0091 0.085 0.1305
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0311 0.2285
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0113 0.1097 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0163 0.0329
Schistosoma mansoni hypothetical protein 0.0355 0.3713 1
Schistosoma mansoni hypothetical protein 0.0041 0.0316 0.0851
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0163 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.0116 0.1119 0.8234
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0088 0.1034
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0421 0.384
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0159 0.028
Echinococcus multilocularis cathepsin L 0.0051 0.0421 0.0368
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.136 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0163 0.5
Brugia malayi cathepsin L precursor 0.0024 0.0129 0.026
Entamoeba histolytica cysteine proteinase 1, putative 0.0051 0.0421 0.384
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0024 0.0129 0.0537
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0316 0.0714
Schistosoma mansoni hypothetical protein 0.0038 0.0274 0.0737
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.085 0.1503
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0024 0.0129 0.0347
Echinococcus multilocularis snurportin 1 0.0355 0.3713 0.3678
Brugia malayi Importin beta-1 subunit 0.0033 0.0227 0.0458
Brugia malayi Cathepsin L-like precursor 0.0091 0.085 0.1716
Onchocerca volvulus 0.0067 0.0596 0.0846
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0051 0.0421 0.1134
Brugia malayi Bromodomain containing protein 0.0083 0.0763 0.1539
Entamoeba histolytica cysteine protease, putative 0.0051 0.0421 0.384
Loa Loa (eye worm) calpain 5 0.0029 0.0177 0.0358
Trypanosoma cruzi cysteine peptidase, putative 0.0027 0.0159 0.0477
Loa Loa (eye worm) cathepsin B 0.0116 0.1119 0.226
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0091 0.085 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0227 0.0458
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.085 0.1503
Plasmodium vivax calpain, putative 0.0041 0.0311 0.2923
Echinococcus granulosus cathepsin L cysteine protease 0.0051 0.0421 0.1001
Echinococcus granulosus snurportin 1 0.0355 0.3713 1
Echinococcus multilocularis cysteine protease 0.0091 0.085 0.0799
Trypanosoma brucei ISWI complex protein 0.0017 0.0049 0.0362
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0024 0.0129 0.0537
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.085 0.1503
Echinococcus multilocularis muscleblind protein 1 0.0172 0.1733 0.1688
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0319 0.3332 0.8973
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0024 0.0129 0.026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.085 0.1503
Leishmania major cathepsin L-like protease 0.0091 0.085 0.6252
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0462 0.0933
Toxoplasma gondii preprocathepsin c precursor, putative 0.0024 0.0129 0.115
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0027 0.0159 0.0321
Brugia malayi CHE-14 protein 0.0049 0.0394 0.0796
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0049 0.0394 0.0796
Entamoeba histolytica cysteine proteinase 2 0.0051 0.0421 0.384
Entamoeba histolytica cysteine protease, putative 0.0051 0.0421 0.384
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.085 0.1503
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0103 0.0985 0.2541
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0116 0.1119 0.3015
Echinococcus granulosus cathepsin l1 0.0091 0.085 0.2173
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.136 1
Entamoeba histolytica cysteine proteinase, putative 0.0091 0.085 0.775
Giardia lamblia Cathepsin B precursor 0.0116 0.1119 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.136 1
Brugia malayi Pre-SET motif family protein 0.0067 0.0596 0.1203
Trypanosoma cruzi cysteine proteinase, putative 0.0051 0.0421 0.1264
Toxoplasma gondii cathepsin B 0.0116 0.1119 1
Schistosoma mansoni hypothetical protein 0.0017 0.0055 0.0148
Schistosoma mansoni calpain-7 (C02 family) 0.0041 0.0311 0.0837
Loa Loa (eye worm) hypothetical protein 0.0027 0.0159 0.0321
Schistosoma mansoni hypothetical protein 0.0047 0.0375 0.1011
Echinococcus granulosus Protein patched homolog 1 0.0049 0.0394 0.0928
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0462 0.0933
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0163 1
Schistosoma mansoni cathepsin F (C01 family) 0.0091 0.085 0.2289
Echinococcus granulosus cathepsin L 0.0024 0.0129 0.0202
Loa Loa (eye worm) hypothetical protein 0.0024 0.0129 0.026
Entamoeba histolytica cysteine protease, putative 0.0051 0.0421 0.384
Echinococcus granulosus importin subunit beta 1 0.0033 0.0227 0.047
Plasmodium vivax serine-repeat antigen (SERA) 0.0024 0.0129 0.0537
Loa Loa (eye worm) hypothetical protein 0.0172 0.1733 0.3499
Trypanosoma cruzi ISWI complex protein 0.0017 0.0049 0.0148
Echinococcus multilocularis cysteine protease 0.0091 0.085 0.0799
Brugia malayi cathepsin B-like cysteine proteinase 0.0319 0.3332 0.6726
Onchocerca volvulus 0.0091 0.085 0.1305
Entamoeba histolytica cysteine protease, putative 0.0051 0.0421 0.384
Leishmania major cathepsin L-like protease 0.0091 0.085 0.6252
Toxoplasma gondii HEAT repeat-containing protein 0.0033 0.0227 0.2026
Onchocerca volvulus Cathepsin L homolog 0.0091 0.085 0.1305
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0421 0.3098
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0024 0.0129 0.0347
Entamoeba histolytica hypothetical protein 0.0024 0.0129 0.1174
Schistosoma mansoni cathepsin C 0.0024 0.0129 0.0347
Brugia malayi Cathepsin L-like precursor 0.0091 0.085 0.1716
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0421 0.384
Schistosoma mansoni calpain C (C02 family) 0.0041 0.0311 0.0837
Echinococcus multilocularis importin subunit beta 1 0.0033 0.0227 0.0173
Trichomonas vaginalis set domain proteins, putative 0.0534 0.5657 1
Schistosoma mansoni zinc finger protein 0.0017 0.0049 0.0133
Onchocerca volvulus 0.0534 0.5657 1
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0421 0.384

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 2.1 ug ml-1 Cytotoxicity against mouse P388 cells after 48 hrs ChEMBL. 2746258
ED50 (functional) = 4.5 ug ml-1 Cytotoxicity against human KB cells after 72 hrs ChEMBL. 2746258
MIC (functional) > 100 ug ml-1 Antimicrobial activity against Escherichia coli after 48 hrs by twofold serial dilution method ChEMBL. 2746258

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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