Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0007 | 0.001 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0339 | 0.0329 | 0.0858 |
Echinococcus granulosus | microtubule associated protein 2 | 0.1431 | 0.1453 | 1 |
Echinococcus multilocularis | adam 17 protease | 0.0421 | 0.0413 | 0.2826 |
Plasmodium vivax | peptide deformylase, putative | 0.9731 | 1 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0526 | 0.0522 | 0.121 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0048 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0018 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.0171 | 0.0396 |
Schistosoma mansoni | ADAM17 peptidase (M12 family) | 0.0421 | 0.0413 | 0.0951 |
Treponema pallidum | polypeptide deformylase (def) | 0.9731 | 1 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0339 | 0.0329 | 0.0858 |
Leishmania major | polypeptide deformylase-like protein, putative | 0.3713 | 0.3803 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0048 | 0.012 |
Loa Loa (eye worm) | glutaminase | 0.4207 | 0.4312 | 1 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0037 | 0.0018 | 0.0035 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0183 | 0.0168 | 0.039 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0037 | 0.0018 | 0.0035 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.0059 | 1 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0036 | 0.0017 | 0.0038 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0016 | 0.003 |
Schistosoma mansoni | Smad4 | 0.0036 | 0.0017 | 0.0032 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0032 | 0.0012 | 0.0064 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0045 | 0.0026 | 0.0053 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0018 | 0.0042 |
Toxoplasma gondii | hypothetical protein | 0.9731 | 1 | 1 |
Mycobacterium leprae | PROBABLE HYDROLASE | 0.0226 | 0.0212 | 0.0045 |
Wolbachia endosymbiont of Brugia malayi | peptide deformylase | 0.9731 | 1 | 0.5 |
Mycobacterium leprae | PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) | 0.9731 | 1 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0018 | 0.0011 |
Echinococcus granulosus | GPCR family 2 | 0.0035 | 0.0016 | 0.0088 |
Plasmodium vivax | SET domain protein, putative | 0.0033 | 0.0013 | 0.0007 |
Brugia malayi | Disintegrin family protein | 0.0042 | 0.0023 | 0.0053 |
Schistosoma mansoni | smad | 0.0036 | 0.0017 | 0.0032 |
Schistosoma mansoni | neprilysin-2 (M13 family) | 0.0092 | 0.0075 | 0.0167 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0063 | 0.0045 | 0.029 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.0119 | 0.0276 |
Brugia malayi | Smad1 | 0.0036 | 0.0017 | 0.0038 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0036 | 0.0017 | 0.0095 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0037 | 0.0018 | 0.0104 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0037 | 0.0018 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0032 | 0.0074 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0037 | 0.0018 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0029 | 0.006 |
Plasmodium falciparum | amino acid transporter, putative | 0.0037 | 0.0018 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0012 | 0.0027 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0013 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0045 | 0.0104 |
Toxoplasma gondii | hypothetical protein | 0.0037 | 0.0018 | 0.0011 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.0675 | 0.0675 | 0.4632 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0018 | 0.0042 |
Echinococcus granulosus | a disintegrin and metalloproteinase with | 0.0199 | 0.0184 | 0.125 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0037 | 0.0018 | 0.0104 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0048 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.0171 | 0.0396 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0076 | 0.0057 | 0.0133 |
Trypanosoma brucei | Peptide deformylase 2 | 0.3713 | 0.3803 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0339 | 0.0328 | 0.0755 |
Echinococcus granulosus | subfamily M12B unassigned peptidase | 0.0042 | 0.0023 | 0.0138 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0219 | 0.0205 | 0.047 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0035 | 0.0016 | 0.0088 |
Loa Loa (eye worm) | matrixin family protein | 0.0412 | 0.0404 | 0.0936 |
Schistosoma mansoni | smad1 5 8 and | 0.0036 | 0.0017 | 0.0032 |
Mycobacterium tuberculosis | Probable peptidoglycan hydrolase | 0.0226 | 0.0212 | 0.021 |
Trypanosoma brucei | Polypeptide deformylase 1 | 0.3713 | 0.3803 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0048 | 0.012 |
Schistosoma mansoni | subfamily M12B unassigned peptidase (M12 family) | 0.0042 | 0.0023 | 0.0046 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0339 | 0.0329 | 0.0858 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0063 | 0.0045 | 0.029 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0018 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0219 | 0.0205 | 0.0476 |
Brugia malayi | Pre-SET motif family protein | 0.0228 | 0.0215 | 0.0498 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0219 | 0.0206 | 0.1398 |
Brugia malayi | Matrix metalloprotease, N-terminal domain containing protein | 0.0226 | 0.0212 | 0.0493 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0111 | 0.0093 | 0.0217 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.0059 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0018 | 0.0011 |
Mycobacterium tuberculosis | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 0.9731 | 1 | 1 |
Onchocerca volvulus | 0.0037 | 0.0018 | 0.0118 | |
Echinococcus granulosus | Smad4 | 0.0036 | 0.0017 | 0.0095 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0007 | 0.001 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0018 | 0.0011 |
Brugia malayi | Matrixin family protein | 0.0449 | 0.0442 | 0.1025 |
Brugia malayi | MH2 domain containing protein | 0.0036 | 0.0017 | 0.0038 |
Mycobacterium ulcerans | hypothetical protein | 0.0179 | 0.0163 | 0.0161 |
Plasmodium vivax | amine transporter, putative | 0.0037 | 0.0018 | 0.0011 |
Onchocerca volvulus | 0.0037 | 0.0018 | 0.0118 | |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0056 | 0.0037 | 0.0235 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0023 | 0.0003 | 0.0006 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0183 | 0.0168 | 0.114 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0013 | 0.0024 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0526 | 0.0522 | 0.121 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0058 | 0.0039 | 0.0096 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0037 | 0.0018 | 0.0104 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0077 | 0.0059 | 0.0388 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0056 | 0.0037 | 0.0235 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0037 | 0.0018 | 0.0035 |
Schistosoma mansoni | Nep2 peptidase (M13 family) | 0.0092 | 0.0075 | 0.0167 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0219 | 0.0206 | 0.1398 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0412 | 0.0404 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0003 | 0.0006 |
Brugia malayi | Matrixin family protein | 0.0186 | 0.0171 | 0.0396 |
Onchocerca volvulus | 0.0051 | 0.0032 | 0.0475 | |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.3713 | 0.3803 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.0059 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0036 | 0.0017 | 0.0038 |
Brugia malayi | ADAMTS-like protease | 0.0031 | 0.0012 | 0.0027 |
Echinococcus granulosus | adam | 0.0073 | 0.0055 | 0.0359 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0037 | 0.0018 | 0.0104 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0013 | 0.0024 |
Echinococcus granulosus | serotonin transporter | 0.0219 | 0.0205 | 0.1397 |
Onchocerca volvulus | 0.026 | 0.0247 | 0.5993 | |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.016 | 0.0145 | 0.0374 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0077 | 0.0059 | 0.0388 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0037 | 0.0018 | 0.0042 |
Loa Loa (eye worm) | matrixin family protein | 0.0449 | 0.0442 | 0.1025 |
Toxoplasma gondii | hypothetical protein | 0.0037 | 0.0018 | 0.0011 |
Echinococcus granulosus | disintegrin and metalloproteinase | 0.0042 | 0.0023 | 0.0138 |
Brugia malayi | Hemopexin family protein | 0.0263 | 0.0251 | 0.0581 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0056 | 0.0037 | 0.0605 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0018 | 0.0042 |
Plasmodium falciparum | peptide deformylase | 0.9731 | 1 | 1 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0045 | 0.0026 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0029 | 0.006 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.3713 | 0.3803 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0048 | 0.012 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0183 | 0.0168 | 0.0384 |
Brugia malayi | metalloprotease disintegrin 16 with thrombospondin type I motif | 0.0199 | 0.0184 | 0.0427 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0035 | 0.0016 | 0.0036 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0179 | 0.0163 | 0.0161 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0036 | 0.0017 | 0.0038 |
Echinococcus granulosus | tumor protein p63 | 0.0347 | 0.0337 | 0.2301 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0037 | 0.0018 | 0.0104 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0675 | 0.0675 | 0.4632 |
Schistosoma mansoni | ADAMTS5 peptidase (M12 family) | 0.0199 | 0.0184 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.0171 | 0.0396 |
Onchocerca volvulus | 0.0263 | 0.0251 | 0.6081 | |
Schistosoma mansoni | endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) | 0.0045 | 0.0026 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0057 | 0.0133 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0048 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.0119 | 0.0276 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.016 | 0.0145 | 0.0374 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0035 | 0.0016 | 0.0088 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0048 | 0.0029 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0168 | 0.039 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0037 | 0.0018 | 0.0104 |
Onchocerca volvulus | Matrilysin homolog | 0.0186 | 0.0171 | 0.4034 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0007 | 0.001 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0183 | 0.0168 | 0.0165 |
Brugia malayi | Matrixin family protein | 0.0186 | 0.0171 | 0.0396 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0018 | 0.0011 |
Brugia malayi | Matrixin family protein | 0.0186 | 0.0171 | 0.0396 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0013 | 0.0031 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0092 | 0.0075 | 0.0167 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0045 | 0.0026 | 0.0053 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0048 | 0.012 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0016 | 0.003 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0219 | 0.0205 | 0.0476 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0013 | 0.0024 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0056 | 0.0037 | 0.0079 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0037 | 0.0018 | 0.0035 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0037 | 0.0018 | 0.0035 |
Brugia malayi | peptidase family M13 containing protein | 0.0045 | 0.0026 | 0.0059 |
Schistosoma mansoni | adam (A disintegrin and metalloprotease | 0.0073 | 0.0055 | 0.0121 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0037 | 0.0018 | 0.0035 |
Onchocerca volvulus | 0.0186 | 0.0171 | 0.4034 | |
Loa Loa (eye worm) | matrix metalloproteinase | 0.0186 | 0.0171 | 0.0396 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0063 | 0.0045 | 0.029 |
Loa Loa (eye worm) | hypothetical protein | 0.0226 | 0.0212 | 0.0493 |
Loa Loa (eye worm) | hypothetical protein | 0.0219 | 0.0205 | 0.0476 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0183 | 0.0168 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0037 | 0.0086 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0036 | 0.0017 | 0.0032 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0036 | 0.0017 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0023 | 0.0053 |
Brugia malayi | MH1 domain containing protein | 0.0036 | 0.0017 | 0.0038 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0135 | 0.0119 | 0.0276 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.0119 | 0.0276 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0067 | 0.0048 | 0.012 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0035 | 0.0016 | 0.0036 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0063 | 0.0045 | 0.029 |
Schistosoma mansoni | endothelin-converting enzyme-related | 0.0045 | 0.0026 | 0.0053 |
Echinococcus granulosus | smad | 0.0036 | 0.0017 | 0.0095 |
Brugia malayi | mbt repeat family protein | 0.0056 | 0.0037 | 0.0086 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0029 | 0.006 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0045 | 0.0026 | 0.0053 |
Toxoplasma gondii | peptidase family M13 protein | 0.0183 | 0.0168 | 0.0162 |
Loa Loa (eye worm) | Smad1 | 0.0036 | 0.0017 | 0.0038 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0007 | 0.001 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1431 | 0.1453 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0053 | 0.0034 | 0.0081 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0048 | 0.012 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0048 | 0.012 |
Schistosoma mansoni | hypothetical protein | 0.0263 | 0.0251 | 0.0575 |
Loa Loa (eye worm) | reprolysin | 0.0042 | 0.0023 | 0.0053 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.3713 | 0.3803 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0018 | 0.0042 |
Brugia malayi | glutaminase DH11.1 | 0.4207 | 0.4312 | 1 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0048 | 0.0029 | 0.0068 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0077 | 0.0059 | 0.0131 |
Schistosoma mansoni | hypothetical protein | 0.0077 | 0.0059 | 0.0131 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0033 | 0.0013 | 0.0007 |
Echinococcus multilocularis | Blood coagulation inhibitor, Disintegrin | 0.0264 | 0.0251 | 0.1714 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0007 | 0.0016 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.3713 | 0.3803 | 1 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0037 | 0.0018 | 0.0104 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0013 | 0.0073 |
Mycobacterium tuberculosis | Possible exported protein | 0.1491 | 0.1515 | 0.1512 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0018 | 0.0042 |
Schistosoma mansoni | subfamily M12B unassigned peptidase (M12 family) | 0.0042 | 0.0023 | 0.0046 |
Mycobacterium ulcerans | peptide deformylase | 0.9731 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0048 | 0.012 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0037 | 0.0018 | 0.0035 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1431 | 0.1453 | 0.3366 |
Mycobacterium tuberculosis | Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) | 0.0336 | 0.0326 | 0.0323 |
Loa Loa (eye worm) | hypothetical protein | 0.0219 | 0.0205 | 0.0476 |
Echinococcus multilocularis | Smad4 | 0.0036 | 0.0017 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0018 | 0.0042 |
Loa Loa (eye worm) | zinc metallopeptidase 4 | 0.0045 | 0.0026 | 0.0059 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0219 | 0.0205 | 0.0476 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0013 | 0.0073 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0056 | 0.0037 | 0.0079 |
Schistosoma mansoni | smad1 5 8 and | 0.0036 | 0.0017 | 0.0032 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0036 | 0.0017 | 0.0095 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0048 | 0.012 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0092 | 0.0075 | 0.0167 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.0059 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 0.0093 | 0.0217 |
Echinococcus multilocularis | smad | 0.0036 | 0.0017 | 0.0095 |
Onchocerca volvulus | 0.0091 | 0.0073 | 0.153 | |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0037 | 0.0018 | 0.0104 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0029 | 0.006 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0048 | 0.012 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0111 | 0.0093 | 0.0217 |
Onchocerca volvulus | 0.0037 | 0.0018 | 0.0118 | |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0018 | 0.0042 |
Echinococcus multilocularis | a disintegrin and metalloproteinase with | 0.0199 | 0.0184 | 0.125 |
Echinococcus multilocularis | serotonin transporter | 0.0219 | 0.0205 | 0.1397 |
Schistosoma mansoni | neprilysin | 0.0048 | 0.0029 | 0.006 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0035 | 0.0016 | 0.0088 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0219 | 0.0205 | 0.0476 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0339 | 0.0329 | 0.0858 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0035 | 0.0016 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0013 | 0.0031 |
Schistosoma mansoni | matrix metallopeptidase-7 (M10 family) | 0.0186 | 0.0171 | 0.039 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.0119 | 0.0276 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0018 | 0.0042 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0135 | 0.0119 | 0.0276 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.016 | 0.0145 | 0.0374 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0037 | 0.0018 | 0.0035 |
Loa Loa (eye worm) | serotonin transporter b | 0.0219 | 0.0205 | 0.0476 |
Echinococcus multilocularis | subfamily M12B unassigned peptidase | 0.0042 | 0.0023 | 0.0138 |
Brugia malayi | hypothetical protein | 0.0077 | 0.0059 | 0.0137 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0012 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0012 | 0.0027 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0048 | 0.012 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0018 | 0.0042 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0061 | 0.0042 | 0.0104 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0526 | 0.0522 | 0.121 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0029 | 0.006 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0035 | 0.0016 | 0.0036 |
Loa Loa (eye worm) | MBCTL1 | 0.0063 | 0.0045 | 0.0104 |
Schistosoma mansoni | matrix metallopeptidase-9 (M10 family) | 0.0144 | 0.0127 | 0.0289 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0122 | 0.0283 |
Echinococcus granulosus | Blood coagulation inhibitor Disintegrin | 0.0264 | 0.0251 | 0.1714 |
Onchocerca volvulus | 0.0219 | 0.0205 | 0.4921 | |
Giardia lamblia | DINP protein human, muc B family | 0.0023 | 0.0003 | 0.5 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0037 | 0.0018 | 0.0035 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0063 | 0.0045 | 0.0098 |
Trichomonas vaginalis | set domain proteins, putative | 0.026 | 0.0247 | 0.0567 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0048 | 0.0029 | 0.0068 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0048 | 0.0029 | 0.0068 |
Mycobacterium ulcerans | epoxide hydrolase EphA | 0.0336 | 0.0326 | 0.0323 |
Brugia malayi | Matrixin family protein | 0.0186 | 0.0171 | 0.0396 |
Schistosoma mansoni | dihydroceramide desaturase | 0.0042 | 0.0023 | 0.0046 |
Echinococcus multilocularis | disintegrin and metalloproteinase | 0.0042 | 0.0023 | 0.0138 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0048 | 0.012 |
Brugia malayi | hypothetical protein | 0.0073 | 0.0055 | 0.0127 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0023 | 0.0003 | 0.0006 |
Plasmodium falciparum | transporter, putative | 0.0037 | 0.0018 | 0.0011 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0023 | 0.0003 | 0.0006 |
Brugia malayi | Peptidase family M13 containing protein | 0.0183 | 0.0168 | 0.039 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0168 | 0.039 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0018 | 0.0042 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0048 | 0.012 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0057 | 0.0127 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0051 | 0.0032 | 0.0067 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0219 | 0.0205 | 0.047 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0048 | 0.012 |
Echinococcus multilocularis | adam | 0.0073 | 0.0055 | 0.0359 |
Schistosoma mansoni | smad1 5 8 and | 0.0036 | 0.0017 | 0.0032 |
Onchocerca volvulus | Matrilysin homolog | 0.0412 | 0.0404 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0122 | 0.0283 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0111 | 0.0093 | 0.0217 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0048 | 0.012 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0037 | 0.0018 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0018 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0073 | 0.0169 |
Mycobacterium ulcerans | glutaminase | 0.4207 | 0.4312 | 0.431 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0056 | 0.0037 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0122 | 0.0283 |
Echinococcus multilocularis | tumor protein p63 | 0.0347 | 0.0337 | 0.2301 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0063 | 0.0045 | 0.0104 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0016 | 0.003 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0056 | 0.0037 | 0.0086 |
Loa Loa (eye worm) | glutaminase 2 | 0.4207 | 0.4312 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0092 | 0.0075 | 0.0167 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0056 | 0.0037 | 0.0235 |
Brugia malayi | MH2 domain containing protein | 0.0036 | 0.0017 | 0.0038 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0007 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0122 | 0.0283 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0037 | 0.0018 | 0.0104 |
Brugia malayi | ADAM-TS Spacer 1 family protein | 0.0031 | 0.0012 | 0.0027 |
Brugia malayi | angiogenesis inhibito | 0.0031 | 0.0012 | 0.0027 |
Mycobacterium ulcerans | hydrolase | 0.0226 | 0.0212 | 0.021 |
Schistosoma mansoni | glutaminase | 0.4207 | 0.4312 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0029 | 0.006 |
Onchocerca volvulus | 0.0056 | 0.0037 | 0.0605 | |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0013 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0168 | 0.039 |
Loa Loa (eye worm) | hypothetical protein | 0.0884 | 0.089 | 0.2063 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0016 | 0.003 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0183 | 0.0168 | 0.114 |
Trichomonas vaginalis | glutaminase, putative | 0.4207 | 0.4312 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0122 | 0.0283 |
Echinococcus granulosus | adam 17 protease | 0.0463 | 0.0456 | 0.3124 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0228 | 0.0215 | 0.0498 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0016 | 0.0036 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0036 | 0.0017 | 0.0095 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0048 | 0.0029 | 0.0068 |
Brugia malayi | mbt repeat family protein | 0.0056 | 0.0037 | 0.0086 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0056 | 0.0037 | 0.0079 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0037 | 0.0018 | 0.0035 |
Echinococcus multilocularis | GPCR, family 2 | 0.0035 | 0.0016 | 0.0088 |
Toxoplasma gondii | hypothetical protein | 0.0055 | 0.0036 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0122 | 0.0283 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IPol (functional) | > 100000 nM | In vitro cytotoxicity of the compound was measured after 4 hr of exposure against L1210 murine leukemia cells | ChEMBL. | 10866397 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.