Detailed information for compound 1045092

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 345.785 | Formula: C19H12ClN5
  • H donors: 1 H acceptors: 3 LogP: 4.21 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccc2c(c1)nc1c2c2nc3n(c2[nH]c1)ncc1c3cccc1.Cl
  • InChi: 1S/C19H11N5.ClH/c1-2-6-12-11(5-1)9-21-24-18(12)23-17-16-13-7-3-4-8-14(13)22-15(16)10-20-19(17)24;/h1-10,20H;1H
  • InChiKey: MDSCIXUHXBCOAD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus GABA-A receptor; anion channel Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 447 aa 25.7 %
Echinococcus granulosus glycine receptor subunit alpha 1 GABA-A receptor; anion channel   467 aa 430 aa 32.3 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 435 aa 29.7 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 468 aa 28.6 %
Brugia malayi Cation transporter family protein GABA-A receptor; anion channel   467 aa 453 aa 28.5 %
Echinococcus multilocularis glycine receptor subunit alpha 1 GABA-A receptor; anion channel   467 aa 430 aa 32.3 %
Echinococcus multilocularis glycine receptor subunit beta GABA-A receptor; anion channel   467 aa 478 aa 28.7 %
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit GABA-A receptor; anion channel   467 aa 379 aa 19.3 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 461 aa 27.8 %
Schistosoma mansoni Cys-loop ligand gated ion channel subunit GABA-A receptor; anion channel   467 aa 479 aa 29.2 %
Onchocerca volvulus Large subunit GTPase 1 homolog GABA-A receptor; anion channel   467 aa 496 aa 26.0 %
Onchocerca volvulus Eukaryotic initiation factor 4A-III homolog GABA-A receptor; anion channel   467 aa 453 aa 26.9 %
Echinococcus granulosus glycine receptor subunit beta GABA-A receptor; anion channel   467 aa 439 aa 29.6 %
Onchocerca volvulus Gamma-aminobutyric acid receptor subunit beta homolog GABA-A receptor; anion channel   467 aa 433 aa 34.6 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 434 aa 26.7 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 494 aa 25.5 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein GABA-A receptor; anion channel   467 aa 454 aa 29.5 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 446 aa 29.1 %
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative GABA-A receptor; anion channel   467 aa 384 aa 19.5 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 446 aa 28.0 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 454 aa 30.4 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein GABA-A receptor; anion channel   467 aa 375 aa 21.9 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 441 aa 33.8 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type homolog GABA-A receptor; anion channel   467 aa 418 aa 19.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0027 0.0009 0.001
Echinococcus multilocularis cyclins 0.0035 0.0069 0.0069
Trypanosoma cruzi cyclin 6, putative 0.0035 0.0069 0.0309
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.005 0.0051
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Brugia malayi hypothetical protein 0.0032 0.005 0.0084
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0009 0.0014
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0038 0.0092 0.0476
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0032 0.005 0.0051
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0027 0.0009 0.001
Entamoeba histolytica hypothetical protein 0.0027 0.0009 0.0049
Loa Loa (eye worm) hypothetical protein 0.0101 0.056 0.081
Onchocerca volvulus 0.0026 0.0005 0.0012
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0027 0.0009 0.0014
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0105 0.0594 0.0597
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0032 0.005 0.0051
Brugia malayi Tachykinin-like peptides receptor 99D 0.0032 0.005 0.0084
Loa Loa (eye worm) hypothetical protein 0.0278 0.1879 0.2718
Echinococcus multilocularis tyrosine protein kinase csk 0.0027 0.0009 0.001
Trichomonas vaginalis cyclin A, putative 0.0035 0.0069 0.0309
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.005 0.0051
Echinococcus granulosus tyrosine protein kinase Src42A 0.0105 0.0594 0.0597
Echinococcus granulosus somatostatin receptor 0.0032 0.005 0.0051
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.003 0.0032 0.0046
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0067 0.0306 0.0307
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0091 0.0489 0.0707
Echinococcus granulosus tachykinin peptides receptor 99D 0.0032 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Schistosoma mansoni amine GPCR 0.0032 0.005 0.0051
Onchocerca volvulus 0.0038 0.0092 0.0199
Brugia malayi serine/threonine kinase 12 0.0226 0.1491 0.2486
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0045 0.0148 0.0149
Plasmodium falciparum protein kinase, putative 0.0027 0.0009 0.0064
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0032 0.005 0.0073
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0048 0.0167 0.0825
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0032 0.005 0.0084
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.004 0.0109 0.0109
Schistosoma mansoni tyrosine kinase 0.0038 0.0092 0.0092
Echinococcus granulosus tyrosine protein kinase pr2 0.0027 0.0009 0.001
Giardia lamblia Kinase, PLK 0.0285 0.1924 1
Entamoeba histolytica hypothetical protein 0.0027 0.0009 0.0049
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.005 0.0051
Brugia malayi Serotonin receptor 0.0032 0.005 0.0084
Echinococcus multilocularis sex peptide receptor 0.0032 0.005 0.0051
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.005 0.0051
Onchocerca volvulus 0.0038 0.0092 0.0199
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.005 0.0073
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.0489 0.2503
Loa Loa (eye worm) TK/DDR protein kinase 0.0027 0.0009 0.0014
Echinococcus granulosus integrin linked protein kinase 0.0027 0.0009 0.001
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0035 0.0069 0.0069
Entamoeba histolytica cyclin, putative 0.0035 0.0069 0.0357
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0027 0.0009 0.0016
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0009 0.0014
Brugia malayi Protein kinase domain containing protein 0.0716 0.5126 0.8547
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0032 0.005 0.0051
Echinococcus granulosus tyrosine protein kinase 0.0027 0.0009 0.001
Echinococcus multilocularis raf serine:threonine protein kinase 0.0027 0.0009 0.001
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0009 0.000000048061
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0069 0.0309
Leishmania major cyclin 0.0035 0.0069 0.0309
Trypanosoma cruzi aurora B kinase, putative 0.0226 0.1491 0.7736
Echinococcus granulosus protein kinase c epsilon type 0.0028 0.0022 0.0022
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0009 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0022 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.005 0.0051
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Loa Loa (eye worm) TK/ROR protein kinase 0.0042 0.0121 0.0175
Trichomonas vaginalis cyclin B, putative 0.0035 0.0069 0.0309
Entamoeba histolytica protein kinase, putative 0.0072 0.0349 0.1811
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0009 0.0049
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Loa Loa (eye worm) CAMK protein kinase 0.0034 0.0064 0.0093
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Echinococcus multilocularis lachesin 0.0034 0.0066 0.0067
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Echinococcus multilocularis orexin receptor type 2 0.0032 0.005 0.0051
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0092 0.0133
Echinococcus granulosus expressed protein 0.037 0.2559 0.2573
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0259 0.0112
Onchocerca volvulus 0.0027 0.0009 0.0021
Schistosoma mansoni serine/threonine kinase 0.0028 0.0022 0.0022
Schistosoma mansoni lipoxygenase 0.0054 0.0216 0.0217
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0027 0.0009 0.001
Brugia malayi Protein kinase domain containing protein 0.0038 0.0092 0.0153
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0027 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Trichomonas vaginalis cyclin B3, putative 0.0035 0.0069 0.0309
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.005 0.0051
Brugia malayi Dopamine receptor protein 2 0.0032 0.005 0.0084
Brugia malayi G protein-coupled receptor 0.0032 0.005 0.0084
Loa Loa (eye worm) hypothetical protein 0.0101 0.056 0.081
Brugia malayi ephrin receptor 1 precursor 0.0077 0.0382 0.0637
Echinococcus granulosus neuropeptide receptor 0.0032 0.005 0.0051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0718 0.5141 0.8573
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0034 0.0064 0.0093
Entamoeba histolytica hypothetical protein 0.0027 0.0009 0.0049
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.005 0.0051
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Loa Loa (eye worm) TK protein kinase 0.0042 0.0121 0.0175
Echinococcus granulosus Protein kinase C brain isozyme 0.0028 0.0022 0.0022
Echinococcus granulosus tyrosine protein kinase csk 0.0027 0.0009 0.001
Onchocerca volvulus 0.0038 0.0092 0.0199
Echinococcus granulosus beta-adrenergic receptor kinase 0.0027 0.0012 0.0012
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0259 0.026
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0012 0.0012
Giardia lamblia Protein 21.1 0.0027 0.0009 0.0049
Leishmania major protein kinase, putative 0.0035 0.0068 0.0308
Schistosoma mansoni plexin 0.0034 0.0062 0.0062
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0027 0.0009 0.001
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0034 0.0066 0.0067
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0009 0.0014
Schistosoma mansoni amine GPCR 0.0032 0.005 0.0051
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0105 0.0594 0.0597
Loa Loa (eye worm) AUR protein kinase 0.0226 0.1491 0.2157
Plasmodium vivax unspecified product 0.0138 0.0837 0.5618
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0022 0.0022
Echinococcus multilocularis c src tyrosine kinase 0.0049 0.0172 0.0173
Onchocerca volvulus 0.0032 0.005 0.0109
Entamoeba histolytica protein kinase, putative 0.0083 0.0432 0.2243
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0048 0.0167 0.0168
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.005 0.0051
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0028 0.0022 0.0032
Trichomonas vaginalis AGC family protein kinase 0.0226 0.1491 0.7736
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.1924 1
Schistosoma mansoni ephrin receptor 0.0133 0.0799 0.0804
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Onchocerca volvulus 0.003 0.0032 0.0068
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0027 0.0009 0.001
Brugia malayi Cyclin, N-terminal domain containing protein 0.0035 0.0069 0.0115
Onchocerca volvulus 0.0034 0.0062 0.0134
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Echinococcus granulosus plexin a4 0.004 0.0108 0.0108
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0027 0.0009 0.001
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Loa Loa (eye worm) TK/FAK protein kinase 0.0523 0.3696 0.5347
Echinococcus granulosus hypothetical protein 0.0032 0.005 0.0051
Echinococcus granulosus lachesin 0.0034 0.0066 0.0067
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Loa Loa (eye worm) TK/ALK protein kinase 0.0027 0.0009 0.0014
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0091 0.0489 0.0491
Loa Loa (eye worm) SRC-1 0.0105 0.0594 0.0859
Onchocerca volvulus 0.0032 0.005 0.0109
Echinococcus multilocularis tyrosine protein kinase HCK 0.0083 0.0432 0.0434
Echinococcus granulosus cyclin dependent kinase 1 0.0091 0.0489 0.0491
Loa Loa (eye worm) melatonin receptor type 1A 0.0032 0.005 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.005 0.0051
Schistosoma mansoni tyrosine kinase 0.0517 0.3653 0.3673
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0068 0.0319 0.0461
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0009 0.0014
Onchocerca volvulus 0.0038 0.0092 0.0199
Echinococcus multilocularis kinase suppressor of Ras 1 0.0027 0.0009 0.001
Echinococcus granulosus nervana 2 0.004 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0034 0.0066 0.0096
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0026 0.0005 0.0008
Echinococcus granulosus neuropeptide receptor 0.0032 0.005 0.0051
Brugia malayi Protein kinase domain containing protein 0.0091 0.0489 0.0815
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Loa Loa (eye worm) hypothetical protein 0.0034 0.0066 0.0096
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0032 0.005 0.0051
Echinococcus granulosus peptide allatostatin:somatostatin 0.0032 0.005 0.0051
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0032 0.005 0.0073
Echinococcus multilocularis neuropeptide receptor 0.0032 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Echinococcus multilocularis natriuretic peptide receptor 1 0.0027 0.0009 0.001
Entamoeba histolytica serine/threonine kinase, putative 0.0027 0.0009 0.0049
Toxoplasma gondii protein kinase domain-containing protein 0.0027 0.0009 0.0064
Loa Loa (eye worm) hypothetical protein 0.0034 0.0062 0.009
Brugia malayi hypothetical protein 0.0032 0.005 0.0084
Trichomonas vaginalis cyclin B, putative 0.0035 0.0069 0.0309
Schistosoma mansoni titin 0.0026 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0034 0.0066 0.0096
Echinococcus granulosus titin 0.0034 0.0064 0.0065
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Echinococcus granulosus tyrosine protein kinase Srms 0.0038 0.0092 0.0092
Echinococcus multilocularis casein kinase ii subunit alpha 0.0138 0.0837 0.0842
Entamoeba histolytica cyclin family protein 0.0035 0.0069 0.0357
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.005 0.0051
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0032 0.005 0.0051
Echinococcus multilocularis somatostatin receptor 0.0032 0.005 0.0051
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0026 0.0005 0.0008
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Plasmodium vivax protein kinase Crk2 0.0091 0.0489 0.3278
Schistosoma mansoni protein kinase 0.0027 0.0009 0.001
Loa Loa (eye worm) projectin 0.0026 0.0005 0.0008
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0027 0.0009 0.0014
Plasmodium falciparum protein kinase 5 0.0091 0.0489 0.3278
Echinococcus granulosus g protein coupled receptor 0.0032 0.005 0.0051
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.1924 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0032 0.005 0.0051
Loa Loa (eye worm) cyclin domain-containing protein 0.0035 0.0069 0.0099
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0045 0.0148 0.0723
Onchocerca volvulus 0.0027 0.0009 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.1924 1
Echinococcus multilocularis ephrin type A receptor 4 A 0.0158 0.0988 0.0993
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0092 0.0133
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0032 0.005 0.0051
Schistosoma mansoni amine GPCR 0.0032 0.005 0.0051
Schistosoma mansoni growth hormone secretagogue receptor 0.0032 0.005 0.0051
Brugia malayi protein-tyrosine kinase 0.0095 0.0514 0.0857
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0032 0.005 0.0051
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Echinococcus granulosus nervana 2 0.004 0.0109 0.0109
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0216 0.0217
Echinococcus multilocularis cyclin B 0.0035 0.0069 0.0069
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.005 0.0051
Echinococcus multilocularis nervana 2 0.004 0.0109 0.0109
Echinococcus multilocularis cyclins 0.0035 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0067 0.0306 0.0442
Echinococcus multilocularis cyclin b3 0.0035 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0148 0.0214
Echinococcus multilocularis G protein coupled receptor 139 0.0032 0.005 0.0051
Schistosoma mansoni histamine h1 receptor 0.0032 0.005 0.0051
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0028 0.0022 0.0022
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0009 0.0049
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Echinococcus multilocularis aurora kinase A 0.0226 0.1491 0.1499
Trypanosoma brucei cdc2-related kinase 1 0.0091 0.0489 0.2503
Echinococcus multilocularis epidermal growth factor receptor 0.0833 0.5997 0.603
Plasmodium falciparum protein kinase, putative 0.0035 0.0068 0.0459
Loa Loa (eye worm) RGC/RGC protein kinase 0.0027 0.0009 0.0014
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0226 0.1491 0.7747
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0032 0.0032
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0023 0.0024
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0034 0.0066 0.0096
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Trypanosoma cruzi cdc2-related kinase 1 0.0091 0.0489 0.2503
Plasmodium vivax protein kinase, putative 0.0035 0.0072 0.048
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.005 0.0051
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Echinococcus multilocularis transfer RNA-Phe 0.0026 0.0005 0.0005
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.005 0.0051
Schistosoma mansoni tyrosine kinase 0.0049 0.0172 0.0173
Echinococcus granulosus tyrosine protein kinase Fyn 0.0105 0.0594 0.0597
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0027 0.0009 0.001
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0543 0.2787
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0349 0.1771
Echinococcus granulosus tyrosine kinase 0.0095 0.0514 0.0517
Loa Loa (eye worm) TK protein kinase 0.0027 0.0009 0.0014
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0027 0.0009 0.001
Entamoeba histolytica hypothetical protein 0.0027 0.0009 0.0049
Trichomonas vaginalis cyclins, putative 0.0035 0.0069 0.0309
Echinococcus granulosus peroxidasin 0.0034 0.0066 0.0067
Schistosoma mansoni protein kinase 0.0188 0.1206 0.1213
Onchocerca volvulus 0.0027 0.0009 0.0021
Echinococcus granulosus tyrosine protein kinase Fyn 0.0105 0.0594 0.0597
Onchocerca volvulus 0.0027 0.0009 0.0021
Brugia malayi SRC-1 0.0105 0.0594 0.099
Echinococcus granulosus Glutaredoxin protein 5 0.004 0.0109 0.0109
Brugia malayi protein unc-22 0.0034 0.0064 0.0107
Schistosoma mansoni hypothetical protein 0.0026 0.0005 0.0005
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.1924 1
Trypanosoma brucei Casein kinase II 0.0138 0.0837 0.4324
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Schistosoma mansoni neuropeptide receptor 0.0032 0.005 0.0051
Entamoeba histolytica protein kinase domain containing protein 0.0035 0.0068 0.0356
Echinococcus granulosus roundabout 2 0.0045 0.0148 0.0149
Echinococcus multilocularis roundabout 2 0.0112 0.0642 0.0645
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0045 0.0148 0.0769
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.005 0.0051
Echinococcus multilocularis heat shock protein 70 0.0027 0.0009 0.001
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0349 0.1771
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0005 0.0009
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0027 0.0009 0.001
Echinococcus granulosus microtubule associated protein 2 0.1365 0.9945 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0032 0.005 0.0051
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0718 0.5141 0.7438
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Schistosoma mansoni cell adhesion molecule 0.0097 0.053 0.0533
Echinococcus multilocularis fmrfamide receptor 0.0032 0.005 0.0051
Trichomonas vaginalis cyclins, putative 0.0035 0.0069 0.0309
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0032 0.005 0.0051
Schistosoma mansoni tyrosine kinase 0.0537 0.3801 0.3822
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0091 0.0489 0.2503
Echinococcus multilocularis expressed protein 0.037 0.2559 0.2573
Loa Loa (eye worm) TK/EGFR protein kinase 0.0833 0.5997 0.8676
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.005 0.0051
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0028 0.0022 0.0022
Brugia malayi plexin A 0.004 0.0108 0.018
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0028 0.0022 0.0022
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0045 0.0148 0.0723
Echinococcus granulosus natriuretic peptide receptor 1 0.0027 0.0009 0.001
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0035 0.0069 0.0309
Echinococcus multilocularis Glutaredoxin protein 5 0.004 0.0109 0.0109
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0052 0.0197 0.098
Echinococcus multilocularis FL cytokine receptor 0.0027 0.0009 0.001
Echinococcus multilocularis 0.0247 0.1644 0.1653
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0105 0.0594 0.0597
Echinococcus granulosus serine:threonine protein kinase N2 0.0028 0.0022 0.0022
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0066 0.0111
Schistosoma mansoni tyrosine protein kinase 0.0027 0.0009 0.001
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0009 0.0049
Echinococcus granulosus raf serine:threonine protein kinase 0.0027 0.0009 0.001
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0009 0.000000048061
Onchocerca volvulus 0.0032 0.005 0.0109
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0092 0.0133
Schistosoma mansoni myosin xvIII 0.0032 0.005 0.0051
Loa Loa (eye worm) protein kinase domain-containing protein 0.0027 0.0009 0.0014
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0259 0.026
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0045 0.0148 0.0993
Schistosoma mansoni titin 0.0034 0.0066 0.0067
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0032 0.005 0.0051
Trypanosoma cruzi polo-like protein kinase, putative 0.0285 0.1924 1
Brugia malayi GnHR receptor homolog 0.0032 0.005 0.0084
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.005 0.0073
Entamoeba histolytica tyrosin kinase, putative 0.0027 0.0009 0.0049
Echinococcus granulosus insulin receptor 0.0716 0.5126 0.5154
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0028 0.0022 0.0032
Loa Loa (eye worm) hypothetical protein 0.0078 0.0387 0.0561
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0349 0.1771
Brugia malayi integrin-linked kinase 0.0027 0.0009 0.0016
Echinococcus multilocularis fmrfamide receptor 0.0032 0.005 0.0051
Brugia malayi G protein-coupled receptor F59B2.13 0.0032 0.005 0.0084
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0032 0.005 0.0051
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0027 0.0009 0.0014
Giardia lamblia Kinase, NEK 0.0027 0.0009 0.0049
Schistosoma mansoni tyrosine kinase 0.0105 0.0594 0.0597
Onchocerca volvulus 0.0032 0.005 0.0109
Echinococcus granulosus contactin 0.0045 0.0148 0.0149
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Schistosoma mansoni protein kinase 0.0035 0.0068 0.0069
Toxoplasma gondii protein kinase 0.0027 0.0009 0.0064
Loa Loa (eye worm) TK/RYK protein kinase 0.0027 0.0009 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0837 0.4324
Echinococcus granulosus sex peptide receptor 0.0032 0.005 0.0051
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0837 0.4324
Plasmodium vivax SET domain protein, putative 0.003 0.0032 0.0211
Entamoeba histolytica hypothetical protein 0.0027 0.0009 0.0049
Echinococcus granulosus tyrosine protein kinase Src64B 0.0105 0.0594 0.0597
Schistosoma mansoni hypothetical protein 0.0032 0.005 0.0051
Echinococcus multilocularis protein kinase 0.0027 0.0009 0.001
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0027 0.0009 0.0014
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0138 0.0837 0.1212
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0009 0.000000048061
Schistosoma mansoni protein kinase 0.0027 0.0009 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0837 0.4324
Echinococcus granulosus activated cdc42 kinase 1 0.0027 0.0009 0.001
Echinococcus granulosus roundabout 2 0.0112 0.0642 0.0645
Echinococcus granulosus protein kinase c iota type 0.0028 0.0022 0.0022
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0067 0.0306 0.0442
Echinococcus granulosus orexin receptor type 2 0.0032 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.005 0.0051
Entamoeba histolytica cysteine surface protein, putative 0.0027 0.0009 0.0049
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0026 0.0005 0.0005
Echinococcus multilocularis neuropeptide receptor A26 0.0032 0.005 0.0051
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.1344 0.1944
Onchocerca volvulus 0.0027 0.0009 0.0021
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Trypanosoma brucei rac serine-threonine kinase, putative 0.0072 0.0349 0.1771
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0045 0.0148 0.0723
Schistosoma mansoni hypothetical protein 0.0027 0.0009 0.001
Brugia malayi hypothetical protein 0.0032 0.005 0.0084
Giardia lamblia Aurora kinase 0.0226 0.1491 0.7747
Echinococcus granulosus tyrosine protein kinase Fyn 0.0105 0.0594 0.0597
Echinococcus granulosus cyclins 0.0035 0.0069 0.0069
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0092 0.0133
Schistosoma mansoni protein kinase 0.0027 0.0009 0.001
Brugia malayi Plexin repeat family protein 0.0034 0.0062 0.0103
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Echinococcus granulosus nephrin 0.0026 0.0005 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0005 0.0009
Echinococcus multilocularis beta adrenergic receptor kinase 0.0027 0.0012 0.0012
Schistosoma mansoni tyrosine kinase 0.0105 0.0594 0.0597
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Echinococcus multilocularis cyclin dependent kinase 5 0.0091 0.0489 0.0491
Schistosoma mansoni nephrin 0.0045 0.0148 0.0149
Giardia lamblia Cyclin A 0.0035 0.0069 0.0357
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0027 0.0009 0.0016
Echinococcus multilocularis tyrosine kinase 0.0038 0.0092 0.0092
Brugia malayi hypothetical protein 0.0032 0.005 0.0084
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0032 0.005 0.0109
Onchocerca volvulus Tyrosine kinase homolog 0.0647 0.4617 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0027 0.0009 0.0021
Echinococcus multilocularis neuroglian 0.0082 0.0417 0.042
Schistosoma mansoni neuropeptide f receptor 76f 0.0032 0.005 0.0051
Entamoeba histolytica protein kinase, putative 0.0068 0.0319 0.1657
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.009 0.009
Toxoplasma gondii aurora kinase 0.0226 0.1491 1
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0035 0.0068 0.0308
Schistosoma mansoni tyrosine kinase 0.0049 0.0172 0.0173
Giardia lamblia Kinase 0.0027 0.0009 0.0049
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0005 0.0009
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0009 0.0049
Schistosoma mansoni protein kinase 0.0027 0.0009 0.001
Brugia malayi Prion-like- 0.0034 0.0066 0.0111
Schistosoma mansoni tyrosine kinase 0.0038 0.0092 0.0092
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0349 0.1771
Echinococcus granulosus neuropeptide receptor A26 0.0032 0.005 0.0051
Loa Loa (eye worm) AGC/NDR protein kinase 0.0028 0.0022 0.0032
Echinococcus granulosus neuroglian 0.0045 0.0148 0.0149
Loa Loa (eye worm) RGC/RGC protein kinase 0.0027 0.0009 0.0014
Entamoeba histolytica protein kinase , putative 0.0226 0.1491 0.7747
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Echinococcus granulosus casein kinase ii subunit alpha 0.0138 0.0837 0.0842
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0027 0.0009 0.001
Loa Loa (eye worm) TK/INSR protein kinase 0.0716 0.5126 0.7415
Entamoeba histolytica tyrosin kinase, putative 0.0027 0.0009 0.0049
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0027 0.0009 0.001
Brugia malayi protein kinase C II. 0.0028 0.0022 0.0037
Echinococcus granulosus tyrosine protein kinase ABL1 0.0038 0.0092 0.0092
Echinococcus granulosus neuropeptide s receptor 0.0032 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.005 0.0051
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0027 0.0009 0.001
Entamoeba histolytica protein kinase domain containing protein 0.0226 0.1491 0.7747
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.005 0.0051
Echinococcus multilocularis cyclins 0.0035 0.0069 0.0069
Schistosoma mansoni tyrosine kinase 0.0564 0.3999 0.4021
Echinococcus granulosus fmrfamide receptor 0.0032 0.005 0.0051
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0105 0.0594 0.0597
Schistosoma mansoni protein kinase 0.0138 0.0837 0.0842
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0009 0.0049
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.004 0.0109 0.0109
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0092 0.0133
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0066 0.0111
Echinococcus multilocularis activin receptor type 0.0035 0.0068 0.0069
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0009 0.0014
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0027 0.0009 0.0016
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0099
Loa Loa (eye worm) hypothetical protein 0.0038 0.0092 0.0133
Loa Loa (eye worm) TYRA-2 protein 0.0032 0.005 0.0073
Brugia malayi C-terminal src kinase protein 1 0.0027 0.0009 0.0016
Echinococcus multilocularis serine:threonine protein kinase 38 0.0028 0.0022 0.0022
Schistosoma mansoni tyrosine kinase 0.0833 0.5997 0.603
Trichomonas vaginalis set domain proteins, putative 0.0235 0.1555 0.8072
Loa Loa (eye worm) plexin A 0.004 0.0108 0.0156
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0012 0.0012
Giardia lamblia Kinase, AGC PKA 0.0048 0.0167 0.087
Trichomonas vaginalis cyclin D, putative 0.0035 0.0069 0.0309
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0053 0.0207 0.03
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0009 0.0049
Echinococcus multilocularis dro:myosuppressin receptor 0.0032 0.005 0.0051
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Brugia malayi bone morphogenetic protein type 1 receptor 0.0027 0.0009 0.0016
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0045 0.0148 0.0149
Schistosoma mansoni cyclin B 0.0035 0.0069 0.0069
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0105 0.0594 0.0597
Schistosoma mansoni protein kinase 0.0027 0.0009 0.001
Brugia malayi Protein kinase domain containing protein 0.0523 0.3696 0.6163
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.005 0.0051
Echinococcus multilocularis receptor type guanylyl cyclase 0.0027 0.0009 0.001
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Plasmodium vivax tyrosine kinase-like protein, putative 0.0027 0.0009 0.0064
Loa Loa (eye worm) AGC/AKT protein kinase 0.0072 0.0349 0.0504
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0837 0.4324
Brugia malayi neuropeptide F receptor 0.0032 0.005 0.0084
Onchocerca volvulus 0.0026 0.0005 0.0012
Echinococcus granulosus alpha 1A adrenergic receptor 0.0032 0.005 0.0051
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0045 0.0148 0.0214
Echinococcus multilocularis tyrosine protein kinase 0.0027 0.0009 0.001
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Echinococcus multilocularis G-protein coupled receptor, putative 0.0032 0.005 0.0051
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0027 0.0009 0.0014
Onchocerca volvulus Neuropeptide F receptor homolog 0.0032 0.005 0.0109
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0009 0.0049
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0027 0.0009 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0009 0.001
Loa Loa (eye worm) TK/CSK protein kinase 0.0027 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Entamoeba histolytica receptor protein kinase, putative 0.0027 0.0009 0.0049
Brugia malayi hypothetical protein 0.0027 0.0009 0.0016
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0036 0.006
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0026 0.0005 0.0008
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0027 0.0009 0.0049
Schistosoma mansoni hypothetical protein 0.0032 0.005 0.0051
Echinococcus granulosus ephrin type A receptor 4 A 0.0158 0.0988 0.0993
Brugia malayi Cyclin, N-terminal domain containing protein 0.0035 0.0069 0.0115
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0092 0.0133
Echinococcus multilocularis plexin a4 0.004 0.0108 0.0108
Echinococcus multilocularis protein KINase family member (kin 25) 0.0027 0.0009 0.001
Entamoeba histolytica serine/threonine kinase, putative 0.0027 0.0009 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.005 0.0051
Echinococcus multilocularis epidermal growth factor receptor 0.0564 0.3999 0.4021
Brugia malayi Tyrosine-protein kinase abl-1 0.0049 0.0172 0.0287
Entamoeba histolytica cell division protein kinase 2, putative 0.0091 0.0489 0.254
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0068 0.0316 0.0318
Echinococcus granulosus retinal guanylyl cyclase 2 0.0027 0.0009 0.001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0148 0.0247
Echinococcus granulosus cyclin b3 0.0035 0.0069 0.0069
Trichomonas vaginalis AGC family protein kinase 0.0226 0.1491 0.7736
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.005 0.0051
Schistosoma mansoni biogenic amine receptor 0.0032 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.005 0.0051
Brugia malayi neuropeptide F receptor 0.0032 0.005 0.0084
Brugia malayi Pre-SET motif family protein 0.0206 0.1344 0.224
Onchocerca volvulus 0.0038 0.0092 0.0199
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0032 0.0032
Loa Loa (eye worm) serine/threonine protein kinase 0.0027 0.0009 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0259 0.0112
Trypanosoma cruzi Protein kinase B 0.0052 0.0197 0.098
Echinococcus granulosus serine/threonine protein kinase 0.0052 0.0197 0.0198
Schistosoma mansoni septate junction protein 0.0034 0.0066 0.0067
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0052 0.0221
Schistosoma mansoni amine GPCR 0.0032 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0027 0.0009 0.001
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0045 0.0148 0.0149
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0032 0.005 0.0051
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Entamoeba histolytica receptor protein kinase, putative 0.0027 0.0009 0.0049
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Schistosoma mansoni tyrosine kinase 0.0716 0.5126 0.5154
Brugia malayi hypothetical protein 0.0032 0.005 0.0084
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0027 0.0009 0.001
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0035 0.0068 0.0308
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Brugia malayi Furin-like cysteine rich region family protein 0.0833 0.5997 1
Brugia malayi hypothetical protein 0.0032 0.005 0.0084
Echinococcus multilocularis g protein coupled receptor 0.0032 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0067 0.0306 0.0442
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0105 0.0594 0.0597
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0049 0.0172 0.0173
Echinococcus multilocularis g protein coupled receptor 0.0032 0.005 0.0051
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0105 0.0594 0.0597
Echinococcus multilocularis protein kinase c iota type 0.0028 0.0022 0.0022
Loa Loa (eye worm) TK protein kinase 0.0095 0.0514 0.0743
Brugia malayi hypothetical protein 0.0032 0.005 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0226 0.1491 0.7736
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0032 0.005 0.0051
Entamoeba histolytica protein kinase, putative 0.0028 0.0022 0.0115
Schistosoma mansoni ephrin receptor 0.0038 0.0091 0.0092
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Echinococcus granulosus Immunoglobulin 0.0067 0.0306 0.0307
Echinococcus multilocularis Immunoglobulin 0.0067 0.0306 0.0307
Brugia malayi putative neuropeptide receptor 0.0032 0.005 0.0084
Onchocerca volvulus 0.0032 0.005 0.0109
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Echinococcus multilocularis g-protein coupled receptor 0.0032 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.005 0.0051
Loa Loa (eye worm) TK/ACK protein kinase 0.0027 0.0009 0.0014
Brugia malayi follicle stimulating hormone receptor 0.0032 0.005 0.0084
Onchocerca volvulus 0.0032 0.005 0.0109
Echinococcus multilocularis titin 0.0034 0.0064 0.0065
Onchocerca volvulus 0.0035 0.0069 0.0149
Brugia malayi Dopamine receptor 0.0032 0.005 0.0084
Brugia malayi Serotonin receptor 0.0032 0.005 0.0084
Schistosoma mansoni titin 0.0034 0.0064 0.0065
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0045 0.0148 0.0723
Schistosoma mansoni cell adhesion molecule 0.0045 0.0148 0.0149
Leishmania major protein kinase, putative 0.0226 0.1491 0.7736
Brugia malayi serine/threonine-protein kinase 6 0.0226 0.1491 0.2486
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0009 0.0049
Entamoeba histolytica protein kinase domain containing protein 0.0033 0.0055 0.0287
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0038 0.0092 0.0092
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Brugia malayi Tyrosine-protein kinase PR2 0.0027 0.0009 0.0016
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0091 0.0489 0.3278
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0226 0.1491 0.1499
Schistosoma mansoni cell adhesion molecule 0.0026 0.0005 0.0005
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0105 0.0594 0.0597
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0027 0.0009 0.0016
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.005 0.0051
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0032 0.005 0.0051
Entamoeba histolytica cyclin family protein 0.0035 0.0069 0.0357
Schistosoma mansoni myosin-binding protein-related 0.0026 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0009 0.000000048061
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0009 0.0049
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0225 0.1481 0.1489
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.005 0.0051
Brugia malayi serine/threonine-protein kinase plk-2 0.0285 0.1924 0.3209
Schistosoma mansoni serine/threonine RGC 0.0027 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Entamoeba histolytica hypothetical protein 0.0027 0.0009 0.0049
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0028 0.0022 0.0022
Brugia malayi ORL1-like opioid receptor 0.0032 0.005 0.0084
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.005 0.0051
Echinococcus granulosus NDR protein kinase 0.0028 0.0022 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.005 0.0051
Echinococcus granulosus g-protein coupled receptor 0.0032 0.005 0.0051
Brugia malayi Receptor family ligand binding region containing protein 0.0027 0.0009 0.0016
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0032 0.005 0.0051
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.005 0.0051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0066 0.0111
Schistosoma mansoni protein kinase 0.0027 0.0009 0.001
Brugia malayi Peroxidasin 0.0034 0.0066 0.0111
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.005 0.0073
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.0008
Onchocerca volvulus 0.0032 0.005 0.0109
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0022 0.0022
Brugia malayi p70 ribosomal S6 kinase beta 0.0068 0.0319 0.0532
Trypanosoma brucei aurora B kinase 0.0226 0.1491 0.7736
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.1491 0.1499
Echinococcus granulosus titin 0.0034 0.0064 0.0065
Trichomonas vaginalis cyclin B, putative 0.0035 0.0069 0.0309
Echinococcus granulosus dro:myosuppressin receptor 0.0032 0.005 0.0051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0121 0.0202
Trichomonas vaginalis cyclins, putative 0.0035 0.0069 0.0309
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0027 0.0009 0.0049
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0092 0.0133
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0027 0.0009 0.001
Entamoeba histolytica ankyrin repeat protein 0.0027 0.0009 0.0049
Toxoplasma gondii AGC kinase 0.0068 0.0319 0.2139
Echinococcus granulosus tyrosine kinase 0.0038 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0034 0.0066 0.0096
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Loa Loa (eye worm) hypothetical protein 0.0034 0.0066 0.0096
Schistosoma mansoni hemicentin 0.0026 0.0005 0.0005
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0035 0.0068 0.0308
Onchocerca volvulus 0.0032 0.005 0.0109
Onchocerca volvulus 0.0027 0.0009 0.0021
Schistosoma mansoni protein kinase 0.0027 0.0009 0.001
Onchocerca volvulus 0.0235 0.1555 0.3369
Echinococcus multilocularis serine:threonine protein kinase N2 0.0028 0.0022 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0022 0.0066
Loa Loa (eye worm) hypothetical protein 0.0045 0.0148 0.0214
Schistosoma mansoni tyrosine kinase 0.0537 0.3801 0.3822
Entamoeba histolytica protein kinase, putative 0.0226 0.1491 0.7747
Brugia malayi larval opioid receptor 0.0032 0.005 0.0084
Onchocerca volvulus 0.0106 0.0602 0.1304
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0138 0.0837 0.5618
Schistosoma mansoni kinase 0.0411 0.2862 0.2878
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0005 0.0009
Echinococcus multilocularis rac serine:threonine kinase 0.0052 0.0197 0.0198
Schistosoma mansoni alpha-1 adrenergic receptor 0.0032 0.005 0.0051
Brugia malayi Casein kinase II, alpha chain 0.0138 0.0837 0.1397
Brugia malayi sulfakinin receptor protein 0.0032 0.005 0.0084
Schistosoma mansoni serine/threonine-protein kinase 0.0052 0.0197 0.0198
Echinococcus multilocularis cyclin B3 1 0.0035 0.0069 0.0069
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0349 0.1771
Brugia malayi SH2 domain containing protein 0.0038 0.0092 0.0153
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0032 0.0032
Plasmodium falciparum protein kinase, putative 0.0027 0.0009 0.0064
Echinococcus granulosus tyrosine protein kinase csk 0.0027 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Echinococcus granulosus neuropeptide FF receptor 2 0.0032 0.005 0.0051
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0042 0.0121 0.0122
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0105 0.0594 0.0597
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0049 0.0172 0.0173
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Entamoeba histolytica hypothetical protein, conserved 0.0027 0.0009 0.0049
Echinococcus granulosus tyrosine kinase 0.0027 0.0009 0.001
Entamoeba histolytica serine/threonine kinase, putative 0.0027 0.0009 0.0049
Echinococcus multilocularis tyrosine protein kinase otk 0.0034 0.0066 0.0067
Loa Loa (eye worm) hypothetical protein 0.0061 0.0266 0.0385
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0028 0.0022 0.0022
Loa Loa (eye worm) TK/Met protein kinase 0.0027 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0028 0.0022 0.0032
Giardia lamblia Kinase, NEK 0.0027 0.0009 0.0049
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0032 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0489 0.0491
Giardia lamblia Hypothetical protein 0.0035 0.0069 0.0357
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0091 0.0489 0.2503
Loa Loa (eye worm) TK protein kinase 0.0027 0.0009 0.0014
Schistosoma mansoni protein kinase 0.0226 0.1491 0.1499
Echinococcus multilocularis cyclin dependent kinase 0.0091 0.0489 0.0491
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Schistosoma mansoni protein tyrosine kinase 0.0027 0.0009 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Giardia lamblia Kinase, CMGC CDK 0.0091 0.0489 0.254
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0027 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Trypanosoma cruzi cdc2-related kinase 3 0.0091 0.0489 0.2503
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0064 0.0107
Loa Loa (eye worm) AGC/PKN protein kinase 0.0028 0.0022 0.0032
Trypanosoma cruzi cyclin, putative 0.0035 0.0069 0.0309
Echinococcus granulosus protein tyrosine kinase 0.0517 0.3653 0.3673
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0035 0.0069 0.0069
Echinococcus multilocularis tyrosine protein kinase pr2 0.0027 0.0009 0.001
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0009 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.005 0.0051
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0226 0.1491 0.7747
Schistosoma mansoni cell adhesion molecule 0.0034 0.0066 0.0067
Echinococcus granulosus defective proboscis extension response 0.0067 0.0306 0.0307
Echinococcus multilocularis protein tyrosine kinase 0.0517 0.3653 0.3673
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0045 0.0148 0.0769
Onchocerca volvulus 0.0032 0.005 0.0109
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Loa Loa (eye worm) hypothetical protein 0.0086 0.0448 0.0649
Brugia malayi Protein kinase domain containing protein 0.0028 0.0022 0.0037
Loa Loa (eye worm) TK protein kinase 0.0027 0.0009 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0032 0.0032
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0045 0.0148 0.0149
Trichomonas vaginalis cyclin D, putative 0.0035 0.0069 0.0309
Loa Loa (eye worm) TK protein kinase 0.0083 0.0432 0.0624
Schistosoma mansoni cyclins 0.0035 0.0069 0.0069
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0027 0.0009 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.005 0.0051
Echinococcus granulosus Down syndrome cell adhesion molecule 0.003 0.0036 0.0036
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0038 0.0092 0.0092
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0027 0.0009 0.0049
Echinococcus multilocularis hemicentin 1 0.0034 0.0066 0.0067
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0027 0.0009 0.000000048061
Schistosoma mansoni atypical protein kinase C 0.0028 0.0022 0.0022
Echinococcus multilocularis protein kinase c epsilon type 0.0028 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Entamoeba histolytica hypothetical protein 0.0027 0.0009 0.0049
Brugia malayi RE15519p 0.0032 0.005 0.0084
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0105 0.0594 0.0597
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0034 0.0066 0.0096
Loa Loa (eye worm) hypothetical protein 0.0078 0.0387 0.0561
Trichomonas vaginalis cyclins, putative 0.0035 0.0069 0.0309
Entamoeba histolytica serine/threonine protein kinase, putative 0.0285 0.1924 1
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0489 0.0491
Brugia malayi Protein kinase domain containing protein 0.0028 0.0022 0.0037
Echinococcus multilocularis transfer RNA-Thr 0.0027 0.0009 0.001
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.005 0.0051
Echinococcus granulosus retinal guanylyl cyclase 2 0.0027 0.0009 0.001
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.005 0.0051
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.0036 0.0052
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1373 1 1
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0727 0.5207 0.5236
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.005 0.0051
Loa Loa (eye worm) AUR protein kinase 0.0226 0.1491 0.2157
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Onchocerca volvulus 0.0032 0.005 0.0109
Echinococcus multilocularis serine:threonine protein kinase N2 0.0028 0.0022 0.0022
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0032 0.005 0.0084
Trypanosoma brucei polo-like protein kinase 0.0285 0.1924 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0027 0.0009 0.0016
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0032 0.005 0.0051
Brugia malayi hypothetical protein 0.0032 0.005 0.0084
Echinococcus multilocularis Immunoglobulin 0.0067 0.0306 0.0307
Schistosoma mansoni nephrin 0.0093 0.0499 0.0502
Echinococcus multilocularis cyclins 0.0035 0.0069 0.0069
Schistosoma mansoni hypothetical protein 0.0032 0.005 0.0051
Entamoeba histolytica casein kinase, putative 0.0138 0.0837 0.4352
Schistosoma mansoni biogenic amine receptor 0.0032 0.005 0.0051
Echinococcus multilocularis g protein coupled receptor 0.0032 0.005 0.0051
Schistosoma mansoni cell adhesion molecule 0.0026 0.0005 0.0005
Echinococcus multilocularis nervana 2 0.004 0.0109 0.0109
Plasmodium falciparum tyrosine kinase-like protein 0.0027 0.0009 0.0064
Brugia malayi Protein kinase domain containing protein 0.0305 0.2076 0.3462
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0009 0.0014
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Schistosoma mansoni opsin-like receptor 0.0032 0.005 0.0051
Schistosoma mansoni opsin-like receptor 0.0032 0.005 0.0051
Echinococcus granulosus receptor type guanylyl cyclase 0.0027 0.0009 0.001
Echinococcus granulosus serotonin receptor 0.0032 0.005 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.1924 1
Brugia malayi Pre-SET motif family protein 0.003 0.0032 0.0053
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0042 0.0121 0.0122
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0105 0.0594 0.0597
Trypanosoma brucei cdc2-related kinase 3 0.0091 0.0489 0.2503
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0032 0.005 0.0073
Entamoeba histolytica tyrosin kinase, putative 0.0033 0.0055 0.0287
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0045 0.0148 0.0149
Loa Loa (eye worm) TK protein kinase 0.0027 0.0009 0.0014
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0027 0.0009 0.001
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0045 0.0148 0.0149
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Onchocerca volvulus 0.0032 0.005 0.0109
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0066 0.0111
Schistosoma mansoni tyrosine kinase 0.0061 0.0264 0.0265
Schistosoma mansoni serine/threonine-protein kinase 0.0052 0.0197 0.0198
Plasmodium falciparum cyclin 0.0035 0.0069 0.0461
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0064 0.0065
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0045 0.0148 0.0149
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0226 0.1491 0.1499
Brugia malayi Protein kinase domain containing protein 0.0072 0.0349 0.0581
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0045 0.0148 0.0993
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0027 0.0009 0.0021
Onchocerca volvulus 0.0032 0.005 0.0109
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Echinococcus multilocularis tyrosine protein kinase Srms 0.0095 0.0514 0.0517
Echinococcus granulosus tyrosine protein kinase csk 0.0027 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0034 0.0066 0.0096
Schistosoma mansoni protein kinase 0.0188 0.1206 0.1213
Echinococcus granulosus tyrosine protein kinase Blk 0.0095 0.0514 0.0517
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Echinococcus granulosus epidermal growth factor receptor 0.0833 0.5997 0.603
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Schistosoma mansoni microtubule-associated protein tau 0.1365 0.9945 1
Onchocerca volvulus 0.0027 0.0009 0.0021
Plasmodium vivax tyrosine kinase-like protein, putative 0.0027 0.0009 0.0064
Brugia malayi Hr1 repeat family protein 0.0028 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0106 0.0602 0.0871
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0022 0.0066
Echinococcus granulosus cyclins 0.0035 0.0069 0.0069
Entamoeba histolytica protein kinase, putative 0.0226 0.1491 0.7747
Echinococcus multilocularis peroxidasin 0.0034 0.0066 0.0067
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0045 0.0148 0.0993
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.0489 0.2503
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0032 0.0032
Schistosoma mansoni roundabout 0.0034 0.0066 0.0067
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Onchocerca volvulus 0.0027 0.0009 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.005 0.0051
Toxoplasma gondii CMGC kinase, CK2 family 0.0138 0.0837 0.5618
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0009 0.0049
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0034 0.0066 0.0144
Onchocerca volvulus Serine\/threonine kinase homolog 0.0285 0.1924 0.4168
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Onchocerca volvulus 0.0606 0.4307 0.933
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0027 0.0009 0.001
Trypanosoma brucei protein kinase, putative 0.0035 0.0068 0.0308
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0022 0.0022
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0188 0.1206 0.1213
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Onchocerca volvulus 0.0032 0.005 0.0109
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0091 0.0489 0.0707
Giardia lamblia Kinase, CMGC CDK 0.0091 0.0489 0.254
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Brugia malayi cell division control protein 2 homolog 0.0091 0.0489 0.0815
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0837 0.4324
Echinococcus multilocularis activated cdc42 kinase 1 0.0027 0.0009 0.001
Echinococcus granulosus cyclin B 0.0035 0.0069 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0009 0.001
Echinococcus multilocularis allatostatin A receptor 0.0032 0.005 0.0051
Brugia malayi G-protein coupled receptor 0.0032 0.005 0.0084
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0027 0.0009 0.001
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0259 0.026
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.005 0.0051
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0048 0.0167 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0009 0.001
Loa Loa (eye worm) TK protein kinase 0.0027 0.0009 0.0014
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0038 0.0092 0.0092
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0022 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0022 0.0022
Entamoeba histolytica cell division protein kinase 2, putative 0.0091 0.0489 0.254
Echinococcus multilocularis tyrosine protein kinase Blk 0.0095 0.0514 0.0517
Echinococcus multilocularis neuroglian 0.0045 0.0148 0.0149
Brugia malayi hypothetical protein 0.0032 0.005 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.005 0.0051
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0045 0.0148 0.0149
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0027 0.0009 0.0014
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0067 0.0306 0.0307
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0028 0.0022 0.0022
Echinococcus granulosus aurora kinase A 0.0226 0.1491 0.1499
Trypanosoma cruzi cdc2-related kinase 1 0.0091 0.0489 0.2503
Echinococcus granulosus g protein coupled receptor 0.0032 0.005 0.0051
Echinococcus granulosus tyrosine protein kinase HCK 0.0083 0.0432 0.0434
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0095 0.0514 0.0517
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.005 0.0051
Echinococcus multilocularis roundabout 2 0.0045 0.0148 0.0149
Echinococcus multilocularis cyclins 0.0035 0.0069 0.0069
Leishmania major casein kinase II, putative 0.0138 0.0837 0.4324
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0092 0.0133
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0092 0.0133
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0045 0.0148 0.0149
Brugia malayi Melatonin receptor type 1A 0.0032 0.005 0.0084
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.1924 1
Trichomonas vaginalis AGC family protein kinase 0.0226 0.1491 0.7736
Trichomonas vaginalis cyclins, putative 0.0035 0.0069 0.0309
Echinococcus granulosus allatostatin A receptor 0.0032 0.005 0.0051
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Loa Loa (eye worm) RGC/RGC protein kinase 0.0027 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Echinococcus granulosus neuroglian 0.0082 0.0417 0.042
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0027 0.0009 0.001
Trypanosoma cruzi cdc2-related kinase 3 0.0091 0.0489 0.2503
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0285 0.1924 0.1935
Brugia malayi Immunoglobulin I-set domain containing protein 0.0078 0.0387 0.0646
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0005 0.0009
Echinococcus multilocularis protein kinase 0.0027 0.0009 0.001
Schistosoma mansoni neuropeptide receptor 0.0032 0.005 0.0051
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0285 0.1924 0.2784
Echinococcus granulosus fibroblast growth factor receptor 4 0.0027 0.0009 0.001
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0028 0.0022 0.0032
Schistosoma mansoni hypothetical protein 0.0032 0.005 0.0051
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0009 0.0014
Echinococcus granulosus activin receptor type 0.0035 0.0068 0.0069
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Echinococcus granulosus retinal guanylyl cyclase 2 0.0027 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.1327 0.9664 1
Loa Loa (eye worm) CAMK/CAMKL/NUAK protein kinase 0.0957 0.6912 1
Loa Loa (eye worm) AUR protein kinase 0.0226 0.1491 0.2157
Schistosoma mansoni tyrosine kinase 0.0537 0.3801 0.3822
Trichomonas vaginalis cyclin B, putative 0.0035 0.0069 0.0309
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Echinococcus granulosus kinase suppressor of Ras 1 0.0027 0.0009 0.001
Echinococcus granulosus cyclins 0.0035 0.0069 0.0069
Schistosoma mansoni tyrosine kinase 0.0564 0.3999 0.4021
Toxoplasma gondii STE kinase 0.0027 0.0009 0.0064
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.003 0.0036 0.0036
Brugia malayi Protein kinase domain containing protein 0.0038 0.0092 0.0153
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.005 0.0051
Echinococcus granulosus tyrosine protein kinase Src42A 0.0068 0.0316 0.0318
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0028 0.0022 0.0032
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Onchocerca volvulus 0.0034 0.0064 0.0139
Entamoeba histolytica serine/threonine kinase, putative 0.0027 0.0009 0.0049
Brugia malayi hypothetical protein 0.0078 0.0387 0.0646
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Echinococcus granulosus cyclins 0.0035 0.0069 0.0069
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0027 0.0009 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.005 0.0051
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0028 0.0022 0.0022
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0032 0.0032
Toxoplasma gondii hypothetical protein 0.0026 0.0007 0.0045
Echinococcus multilocularis neuropeptide s receptor 0.0032 0.005 0.0051
Echinococcus granulosus twitchin 0.009 0.0476 0.0479
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0027 0.0012 0.0017
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0226 0.1491 0.7747
Entamoeba histolytica hypothetical protein 0.0027 0.0009 0.0049
Schistosoma mansoni tyrosine kinase 0.0716 0.5126 0.5154
Brugia malayi Fibronectin type III domain containing protein 0.0078 0.0387 0.0646
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0027 0.0009 0.001
Onchocerca volvulus 0.0032 0.005 0.0109
Schistosoma mansoni septate junction protein 0.0034 0.0066 0.0067
Echinococcus granulosus c src tyrosine kinase 0.0049 0.0172 0.0173
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0099
Echinococcus multilocularis cyclins 0.0035 0.0069 0.0069
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0048 0.0167 0.1124
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0067 0.0306 0.0307
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0032 0.005 0.0051
Echinococcus granulosus hemicentin 1 0.0034 0.0066 0.0067
Echinococcus multilocularis tyrosine protein kinase Abl 0.0049 0.0172 0.0173
Entamoeba histolytica serine/threonine kinase, putative 0.0027 0.0009 0.0049
Echinococcus granulosus 7tm_1 domain containing protein 0.0032 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Entamoeba histolytica protein kinase, putative 0.0072 0.0349 0.1811
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0066 0.0111
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Schistosoma mansoni opsin-like receptor 0.0032 0.005 0.0051
Brugia malayi Guanylyl cyclase protein 23 0.0027 0.0009 0.0016
Echinococcus multilocularis roundabout 2 0.0045 0.0148 0.0149
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0091 0.0489 0.0707
Schistosoma mansoni neuropeptide receptor 0.0032 0.005 0.0051
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0564 0.3999 0.4021
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Entamoeba histolytica serine/threonine kinase, putative 0.0027 0.0009 0.0049
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0009 0.0049
Entamoeba histolytica protein kinase, putative 0.0033 0.0059 0.0306
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0049 0.0172 0.0173
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.0489 0.2503
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0259 0.0116
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0045 0.0148 0.0769
Echinococcus granulosus protein kinase C gamma type 0.0028 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Echinococcus granulosus cyclin B3 1 0.0035 0.0069 0.0069
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0034 0.0066 0.0067
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0148 0.0247
Loa Loa (eye worm) TK/EPH protein kinase 0.0162 0.1016 0.147
Brugia malayi Cyclin, N-terminal domain containing protein 0.0035 0.0069 0.0115
Giardia lamblia Kinase, CMGC CK2 0.0138 0.0837 0.4352
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0225 0.1481 0.1489
Echinococcus multilocularis neuropeptide FF receptor 2 0.0032 0.005 0.0051
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0035 0.0068 0.0459
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0259 0.1302
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0022 0.0022
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0259 0.1735
Echinococcus multilocularis serotonin receptor 0.0032 0.005 0.0051
Echinococcus multilocularis tyrosine protein kinase csk 0.0027 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0837 0.4324
Entamoeba histolytica cyclin, putative 0.0035 0.0069 0.0357
Loa Loa (eye worm) hypothetical protein 0.0034 0.0066 0.0096
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0005 0.0009
Schistosoma mansoni neuroglian 0.0045 0.0148 0.0149
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.005 0.0051
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.005 0.0051
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0032 0.005 0.0084
Brugia malayi AKH receptor 0.0032 0.005 0.0084
Brugia malayi G-protein coupled receptor 0.0032 0.005 0.0084
Echinococcus multilocularis tyrosine protein kinase shark 0.0038 0.0092 0.0092
Trypanosoma cruzi polo-like protein kinase, putative 0.0285 0.1924 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.005 0.0051
Echinococcus multilocularis microtubule associated protein 2 0.1365 0.9945 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0148 0.0247
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0032 0.005 0.0073
Echinococcus multilocularis integrin linked protein kinase 0.0027 0.0009 0.001
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Schistosoma mansoni amine GPCR 0.0032 0.005 0.0051
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Echinococcus granulosus activated cdc42 kinase 1 0.0027 0.0009 0.001
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0188 0.1206 0.1213
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0012 0.0012
Brugia malayi serine/threonine protein kinase 6 0.0226 0.1491 0.2486
Entamoeba histolytica ankyrin repeat protein 0.0027 0.0009 0.0049
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0349 0.1771
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Schistosoma mansoni neuropeptide receptor 0.0032 0.005 0.0051
Onchocerca volvulus 0.0027 0.0009 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0285 0.1924 0.1935
Brugia malayi putative neuropeptide receptor NPR1 0.0032 0.005 0.0084
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0027 0.0009 0.001
Giardia lamblia G2/mitotic-specific cyclin B 0.0035 0.0069 0.0357
Trichomonas vaginalis cyclin B, putative 0.0035 0.0069 0.0309
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.005 0.0073
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0226 0.1491 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0259 0.0112
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0027 0.0009 0.001
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.005 0.0051
Echinococcus granulosus 7TM GPCR rhodopsin 0.0032 0.005 0.0051
Echinococcus granulosus tyrosine protein kinase shark 0.0038 0.0092 0.0092
Entamoeba histolytica hypothetical protein 0.0027 0.0009 0.0049
Echinococcus multilocularis hemicentin 1 0.0034 0.0066 0.0067
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0285 0.1924 1
Echinococcus multilocularis serotonin receptor 0.0032 0.005 0.0051
Entamoeba histolytica protein kinase 2, putative 0.0048 0.0167 0.087
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0027 0.0012 0.002
Brugia malayi hypothetical protein 0.0027 0.0009 0.0016
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0032 0.005 0.0084
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0027 0.0009 0.0014
Brugia malayi Protein kinase domain containing protein 0.0038 0.0092 0.0153
Echinococcus granulosus serine threonine protein kinase nrc 0.0048 0.0167 0.0168
Echinococcus granulosus tyrosine protein kinase Lyn 0.0113 0.0653 0.0656
Echinococcus granulosus protein kinase 0.0027 0.0009 0.001
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0092 0.0133
Loa Loa (eye worm) hypothetical protein 0.0078 0.0387 0.0561
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0197 0.1025
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0027 0.0012 0.0017
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0349 0.1771
Echinococcus multilocularis cyclins 0.0035 0.0069 0.0069
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0197 0.1025
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.005 0.0051
Plasmodium falciparum casein kinase 2, alpha subunit 0.0138 0.0837 0.5618
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0543 0.2787
Echinococcus multilocularis tyrosine kinase 0.0027 0.0009 0.001
Loa Loa (eye worm) TK protein kinase 0.0027 0.0009 0.0014
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0285 0.1924 0.1935
Schistosoma mansoni protein kinase 0.0027 0.0009 0.001
Onchocerca volvulus 0.0038 0.0092 0.0199
Brugia malayi hypothetical protein 0.0038 0.0092 0.0153
Entamoeba histolytica tyrosin kinase, putative 0.0027 0.0009 0.0049
Plasmodium falciparum tyrosine kinase-like protein 0.0027 0.0009 0.0064
Schistosoma mansoni cell adhesion molecule 0.0045 0.0148 0.0149
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0066 0.0111
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.1924 1
Onchocerca volvulus 0.0032 0.005 0.0109
Echinococcus multilocularis neuropeptide receptor 0.0032 0.005 0.0051
Echinococcus granulosus roundabout 2 0.0045 0.0148 0.0149
Brugia malayi Protein kinase domain containing protein 0.0038 0.0092 0.0153
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0045 0.0148 0.0247
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.005 0.0051
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0032 0.005 0.0051
Echinococcus multilocularis tyrosine protein kinase csk 0.0027 0.0009 0.001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0032 0.0211
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0032 0.005 0.0051
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.005 0.0051
Brugia malayi Raf kinase 0.0027 0.0009 0.0016
Brugia malayi Dopamine receptor protein 1 0.0032 0.005 0.0084
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.005 0.0051
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Onchocerca volvulus 0.0032 0.005 0.0109
Trypanosoma cruzi casein kinase II, putative 0.0138 0.0837 0.4324
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0216 0.0217
Loa Loa (eye worm) RGC/RGC protein kinase 0.0027 0.0009 0.0014
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0009 0.0049
Plasmodium falciparum serine/threonine protein kinase, putative 0.0226 0.1491 1
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0837 0.4324
Brugia malayi Protein kinase domain containing protein 0.0027 0.0009 0.0016
Trypanosoma brucei mitotic cyclin 6 0.0035 0.0069 0.0309
Entamoeba histolytica hypothetical protein 0.0027 0.0009 0.0049
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0086 0.0448 0.0451
Schistosoma mansoni cyclin B3 0.0035 0.0069 0.0069
Echinococcus multilocularis tyrosine protein kinase csk 0.0027 0.0009 0.001
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Echinococcus granulosus cyclin dependent kinase 5 0.0091 0.0489 0.0491
Echinococcus granulosus cyclin dependent kinase 0.0091 0.0489 0.0491
Echinococcus granulosus cyclins 0.0035 0.0069 0.0069
Schistosoma mansoni vesicular amine transporter 0.0067 0.0306 0.0307
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0095 0.0514 0.0517
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0032 0.005 0.0084
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0045 0.0148 0.0723
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0048 0.0167 0.1124
Entamoeba histolytica protein kinase, putative 0.0027 0.0009 0.0049
Brugia malayi SH2 domain containing protein 0.0038 0.0092 0.0153
Echinococcus granulosus g protein coupled receptor 0.0032 0.005 0.0051
Echinococcus granulosus epidermal growth factor receptor 0.0564 0.3999 0.4021
Echinococcus multilocularis cyclin dependent kinase 1 0.0091 0.0489 0.0491
Loa Loa (eye worm) TK protein kinase 0.0027 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0622
Onchocerca volvulus 0.0032 0.005 0.0109
Trypanosoma cruzi CYC2-like cyclin, putative 0.0035 0.0069 0.0309
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0032 0.005 0.0051
Entamoeba histolytica hypothetical protein 0.0027 0.0009 0.0049
Entamoeba histolytica protein kinase domain containing protein 0.0138 0.0837 0.4352
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Brugia malayi Protein kinase domain containing protein 0.0038 0.0092 0.0153
Brugia malayi hypothetical protein 0.0032 0.005 0.0084
Loa Loa (eye worm) TK/ABL protein kinase 0.0038 0.0092 0.0133
Echinococcus multilocularis serine threonine protein kinase 0.0028 0.0022 0.0022
Echinococcus granulosus G protein coupled receptor 139 0.0032 0.005 0.0051
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0027 0.0009 0.0064
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0032 0.005 0.0073
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0073
Echinococcus multilocularis insulin receptor 0.0716 0.5126 0.5154
Echinococcus granulosus tyrosine protein kinase otk 0.0034 0.0066 0.0067
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.005 0.0051
Schistosoma mansoni biogenic amine receptor 0.0032 0.005 0.0051
Schistosoma mansoni adenoreceptor 0.0032 0.005 0.0051
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0727 0.5207 0.5236
Echinococcus multilocularis cyclin dependent kinase 1 0.0091 0.0489 0.0491
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0009 0.0049
Schistosoma mansoni tyrosine kinase 0.0027 0.0009 0.001
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0027 0.0009 0.001
Trypanosoma cruzi cyclin, putative 0.0035 0.0069 0.0309

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 200 nM In vitro affinity at the Benzodiazepine receptor (BzR) is its ability to displace [3H]-diazepam from BzR. ChEMBL. 1331457

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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