Detailed information for compound 1137861

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 617.758 | Formula: C26H47N7O8S
  • H donors: 9 H acceptors: 8 LogP: -2.29 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 3
  • SMILES: NCC[C@@H]1NC(=O)CCCCCSC[C@H](NC1=O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)[C@H](O)C)C(C)C)[C@H](O)C
  • InChi: 1S/C26H47N7O8S/c1-13(2)19(25(40)32-20(14(3)34)22(28)37)31-26(41)21(15(4)35)33-24(39)17-12-42-11-7-5-6-8-18(36)29-16(9-10-27)23(38)30-17/h13-17,19-21,34-35H,5-12,27H2,1-4H3,(H2,28,37)(H,29,36)(H,30,38)(H,31,41)(H,32,40)(H,33,39)/t14-,15-,16+,17+,19+,20+,21+/m1/s1
  • InChiKey: IQSDTIOMNJCKRS-DGONOLKGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDasubunit precursor Get druggable targets OG5_128922 All targets in OG5_128922
Schistosoma japonicum ko:K00730 dolichyl-diphosphooligosaccharide--protein glycosyltransferase [EC2.4.1.119], putative Get druggable targets OG5_128922 All targets in OG5_128922
Echinococcus granulosus dolichyl diphosphooligosaccharide protein Get druggable targets OG5_128922 All targets in OG5_128922
Toxoplasma gondii dolichyl-diphosphooligosaccharide--protein glycosyltransferase Get druggable targets OG5_128922 All targets in OG5_128922
Entamoeba histolytica dolichyl-diphosphooligosaccharide-protein glycotransferase, putative Get druggable targets OG5_128922 All targets in OG5_128922
Schistosoma mansoni dolichyl-diphosphooligosaccharide-protein glycosyltransferase Get druggable targets OG5_128922 All targets in OG5_128922
Cryptosporidium hominis dolichyl-di-phosphooligosaccharide-protein glycotransferase (oligosaccharyltransferase)-related Get druggable targets OG5_128922 All targets in OG5_128922
Plasmodium knowlesi dolichyl-diphosphooligosaccharide--protein glycosyltransferase, putative Get druggable targets OG5_128922 All targets in OG5_128922
Plasmodium yoelii hypothetical protein Get druggable targets OG5_128922 All targets in OG5_128922
Candida albicans oligosaccharyl transferase, beta subunit Get druggable targets OG5_128922 All targets in OG5_128922
Entamoeba histolytica dolichyl-di-phosphooligosaccharide-protein glycotransferase, putative Get druggable targets OG5_128922 All targets in OG5_128922
Cryptosporidium parvum dolichyl-diphosphooligosaccharide-protein glycosyltransferase beta subunit (Wbp1p) Get druggable targets OG5_128922 All targets in OG5_128922
Plasmodium vivax dolichyl-diphosphooligosaccharide--protein glycosyltransferase, putative Get druggable targets OG5_128922 All targets in OG5_128922
Candida albicans oligosaccharyl transferase, beta subunit Get druggable targets OG5_128922 All targets in OG5_128922
Neospora caninum dolichyl-di-phosphooligosaccharide-protein glycotransferase, putative Get druggable targets OG5_128922 All targets in OG5_128922
Plasmodium berghei dolichyl-diphosphooligosaccharide--protein glycosyltransferase, putative Get druggable targets OG5_128922 All targets in OG5_128922
Echinococcus multilocularis dolichyl diphosphooligosaccharide protein Get druggable targets OG5_128922 All targets in OG5_128922
Plasmodium falciparum dolichyl-diphosphooligosaccharide--protein glycosyltransferase, putative Get druggable targets OG5_128922 All targets in OG5_128922
Loa Loa (eye worm) dolichyl-di-phosphooligosaccharide-protein glycotransferase Get druggable targets OG5_128922 All targets in OG5_128922
Trichomonas vaginalis dolichyl-diphosphooligosaccharide--protein glycosyltransferase, putative Get druggable targets OG5_128922 All targets in OG5_128922
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi hypothetical protein, conserved 0.0279 0.1618 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0195 0.0322
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0373 0.0795
Loa Loa (eye worm) hypothetical protein 0.001 0.0019 0.0027
Loa Loa (eye worm) hypothetical protein 0.0036 0.0172 0.036
Brugia malayi B-box zinc finger family protein 0.0014 0.0045 0.0085
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0027 0.0044
Toxoplasma gondii Bardet-Biedl syndrome 5, putative 0.0014 0.0045 0.0085
Trichomonas vaginalis ankyrin, putative 0.0014 0.0045 0.0091
Entamoeba histolytica dolichyl-di-phosphooligosaccharide-protein glycotransferase, putative 0.0108 0.06 0.6487
Onchocerca volvulus 0.0036 0.0172 0.036
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0172 0.1031
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0148 0.0307
Trichomonas vaginalis esterase, putative 0.0036 0.0172 0.0367
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0019 0.0078
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0115 0.0236
Echinococcus multilocularis E3 ubiquitin protein ligase Bre1 0.0014 0.0045 0.0039
Toxoplasma gondii helicase, putative 0.0014 0.0045 0.0085
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0027 0.0044
Mycobacterium leprae Probable lipase LipE 0.0036 0.0172 1
Brugia malayi nuclear receptor NHR-88 0.0011 0.0027 0.0044
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Entamoeba histolytica zinc finger domain containing protein 0.0014 0.0045 0.0426
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0027 0.0044
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0279 0.1618 0.3494
Loa Loa (eye worm) hypothetical protein 0.0104 0.0578 0.124
Echinococcus granulosus E3 ubiquitin protein ligase MYLIP 0.0014 0.0045 0.0067
Entamoeba histolytica hypothetical protein 0.001 0.0019 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0014 0.0045 0.0091
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0259 0.043
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0134 0.0282
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0134 0.0282
Schistosoma mansoni hypothetical protein 0.0039 0.0195 0.0409
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.001 0.0019 0.0027
Giardia lamblia Zinc finger domain 0.0014 0.0045 1
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0008 0.0006 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Echinococcus multilocularis ring and YY1 binding protein 0.0279 0.1618 0.1612
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0045 0.0242
Giardia lamblia Hypothetical protein 0.0014 0.0045 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0027 0.0044
Toxoplasma gondii hypothetical protein 0.0014 0.0045 0.0085
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0027 0.002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0259 0.0252
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Loa Loa (eye worm) hypothetical protein 0.0026 0.0115 0.0236
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0172 0.1315
Trichomonas vaginalis antibiotic synthetase, putative 0.0008 0.0006 0.0006
Onchocerca volvulus RING finger protein 141 homolog 0.0014 0.0045 0.0085
Giardia lamblia Ribonuclease 0.0014 0.0045 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0172 0.036
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0172 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0783 0.4618 1
Echinococcus multilocularis SWI:SNF matrix associated 0.0783 0.4618 0.4615
Plasmodium falciparum E3 ubiquitin-protein ligase, putative 0.0014 0.0045 0.0085
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0115 0.0676
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Giardia lamblia Zinc finger domain 0.0014 0.0045 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0104 0.0578 0.124
Schistosoma mansoni patched 1 0.0042 0.0209 0.044
Schistosoma mansoni zinc finger protein 0.0279 0.1618 0.3494
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Trypanosoma cruzi metacaspase, putative 0.0029 0.0134 0.0791
Giardia lamblia Sentrin specific protease, putative 0.0014 0.0045 0.9865
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0069 0.0373 0.0795
Brugia malayi Cell death protein 3 precursor 0.0029 0.0134 0.0276
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0259 0.0252
Schistosoma mansoni hypothetical protein 0.004 0.02 0.0421
Trichomonas vaginalis sex-determining protein fem-1, putative 0.0014 0.0045 0.0091
Trypanosoma brucei ring finger containing protein 0.0014 0.0045 0.0242
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0085
Schistosoma mansoni hypothetical protein 0.0783 0.4618 1
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0783 0.4618 0.4615
Leishmania major hypothetical protein, conserved 0.0279 0.1618 1
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0279 0.1618 1
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0209 0.0446
Brugia malayi beta-lactamase 0.0036 0.0172 0.036
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0027 0.0044
Loa Loa (eye worm) histone methyltransferase 0.001 0.0019 0.0027
Brugia malayi hypothetical protein 0.0014 0.0045 0.0085
Chlamydia trachomatis SWIB complex protein 0.0783 0.4618 1
Trypanosoma brucei predicted zinc finger protein 0.0014 0.0045 0.0242
Trypanosoma brucei hypothetical protein, conserved 0.0279 0.1618 1
Schistosoma mansoni hypothetical protein 0.004 0.02 0.0421
Entamoeba histolytica zinc finger domain containing protein 0.0014 0.0045 0.0426
Entamoeba histolytica zinc finger domain containing protein 0.0014 0.0045 0.0426
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0279 0.1618 1
Leishmania major hypothetical protein, conserved 0.0279 0.1618 1
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0045 0.0242
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0014 0.0045 0.0084
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Brugia malayi hypothetical protein 0.001 0.0019 0.0027
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0783 0.4618 1
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.001 0.0019 0.0754
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Schistosoma mansoni cpg binding protein 0.0033 0.0159 0.033
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0027 0.0044
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0027 0.0044
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0045 0.009
Plasmodium falciparum RING zinc finger protein, putative 0.0014 0.0045 0.0085
Loa Loa (eye worm) Ulp1 protease 0.0014 0.0045 0.0084
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0.0019 0.0078
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0045 0.0422
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0104 0.0578 0.124
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Loa Loa (eye worm) hypothetical protein 0.0279 0.1618 0.3494
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0134 0.0282
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0539 0.0533
Echinococcus multilocularis tumor protein p63 0.0994 0.5871 0.5868
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0172 0.0283
Schistosoma mansoni dolichyl-diphosphooligosaccharide-protein glycosyltransferase 0.0108 0.06 0.1288
Plasmodium falciparum trophozoite exported protein 1 0.0014 0.0045 0.0085
Onchocerca volvulus 0.0146 0.0826 0.1778
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0008 0.0006 0.0048
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0019 0.0021
Echinococcus multilocularis caspase 3 0.008 0.0434 0.0428
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0014 0.0045 0.0091
Echinococcus granulosus caspase 3 0.008 0.0434 0.073
Giardia lamblia Hypothetical protein 0.0014 0.0045 1
Loa Loa (eye worm) hypothetical protein 0.0097 0.0539 0.1156
Plasmodium vivax metacaspase 1, putative 0.0029 0.0134 0.0276
Leishmania major hypothetical protein, conserved 0.0014 0.0045 0.0242
Giardia lamblia Ser/Thr protein kinase 0.0014 0.0045 1
Leishmania major hypothetical protein, conserved 0.0014 0.0045 0.0242
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0172 0.1315
Leishmania major hypothetical protein, conserved 0.0014 0.0045 0.0242
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0027 0.0044
Giardia lamblia Kinase 0.0014 0.0045 1
Schistosoma mansoni hypothetical protein 0.0783 0.4618 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0027 0.0044
Loa Loa (eye worm) hypothetical protein 0.0011 0.0027 0.0044
Loa Loa (eye worm) hypothetical protein 0.0019 0.0076 0.0152
Brugia malayi latrophilin 2 splice variant baaae 0.0071 0.0383 0.0817
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0014 0.0045 0.0091
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0115 0.6556
Loa Loa (eye worm) dolichyl-di-phosphooligosaccharide-protein glycotransferase 0.0108 0.06 0.1288
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0014 0.0045 0.024
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0014 0.0045 0.0039
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0279 0.1618 0.3494
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Loa Loa (eye worm) hypothetical protein 0.0011 0.0027 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0045 0.0242
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0045 0.009
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0134 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0019 0.0034
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0279 0.1618 1
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0539 0.1156
Loa Loa (eye worm) hypothetical protein 0.0011 0.0027 0.0044
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0115 0.0236
Onchocerca volvulus 0.0036 0.0172 0.036
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0115 0.6556
Echinococcus multilocularis caspase 2 0.0029 0.0134 0.0127
Echinococcus granulosus tumor protein p63 0.0994 0.5871 1
Onchocerca volvulus 0.0011 0.0027 0.0044
Loa Loa (eye worm) hypothetical protein 0.0279 0.1618 0.3494
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.001 0.0019 0.0754
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Echinococcus multilocularis expressed conserved protein 0.0091 0.0504 0.0498
Echinococcus multilocularis 0.0014 0.0045 0.0039
Leishmania major hypothetical protein, conserved 0.0014 0.0045 0.0242
Brugia malayi SWIB/MDM2 domain containing protein 0.0783 0.4618 1
Onchocerca volvulus 0.0036 0.0172 0.036
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0045 0.0242
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0027 0.0044
Trypanosoma cruzi hypothetical protein 0.0014 0.0045 0.0242
Onchocerca volvulus 0.0014 0.0045 0.0085
Loa Loa (eye worm) hypothetical protein 0.0019 0.0076 0.0152
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0172 0.1315
Schistosoma mansoni hypothetical protein 0.0014 0.0045 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Schistosoma mansoni DNA ligase IV 0.001 0.0019 0.0027
Leishmania major metacaspase, putative 0.0029 0.0134 0.0791
Echinococcus multilocularis RING finger and transmembrane domain containing protein 0.0014 0.0045 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Entamoeba histolytica zinc finger domain containing protein 0.0014 0.0045 0.0426
Schistosoma mansoni zinc finger protein 0.0014 0.0045 0.0085
Loa Loa (eye worm) hypothetical protein 0.0026 0.0115 0.0236
Echinococcus multilocularis sentrin specific protease 7 0.0162 0.0922 0.0916
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0027 0.002
Trypanosoma cruzi hypothetical protein 0.0014 0.0045 0.0242
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.007 0.0533
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0156 0.015
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0027 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Toxoplasma gondii dolichyl-diphosphooligosaccharide--protein glycosyltransferase 0.0108 0.06 0.1288
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0014 0.0045 0.024
Loa Loa (eye worm) RNA binding protein 0.0069 0.0373 0.0795
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0115 0.6556
Schistosoma mansoni ring finger protein 151 0.0014 0.0045 0.0085
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0539 0.0909
Leishmania major hypothetical protein, conserved 0.0279 0.1618 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0357 0.0761
Plasmodium vivax replication factor C subunit 1, putative 0.001 0.0019 0.0027
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0076 0.0152
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0076 0.0152
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger) containing protein, putative 0.0014 0.0045 0.0242
Entamoeba histolytica zinc finger domain containing protein 0.0014 0.0045 0.0426
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0115 0.0676
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0076 0.0581
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.007 0.0533
Schistosoma mansoni hypothetical protein 0.0033 0.0156 0.0325
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Schistosoma mansoni mind bomb 0.0014 0.0045 0.0085
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0783 0.4618 1
Brugia malayi CXXC zinc finger family protein 0.0031 0.0148 0.0307
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0027 0.0044
Trypanosoma brucei DNA repair protein, putative 0.0014 0.0045 0.0242
Trichomonas vaginalis ion channel nompc, putative 0.0014 0.0045 0.0091
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0279 0.1618 0.3494
Schistosoma mansoni peter pan-related 0.0014 0.0045 0.0085
Giardia lamblia Hypothetical protein 0.0014 0.0045 1
Echinococcus multilocularis dolichyl diphosphooligosaccharide protein 0.0108 0.06 0.0594
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0019 0.0034
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0027 0.002
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0373 0.0795
Loa Loa (eye worm) hypothetical protein 0.0042 0.0209 0.044
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0014 0.0045 0.0091
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0085
Brugia malayi Hypothetical RING finger protein C16C10.7 in chromosome III 0.0014 0.0045 0.0085
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.001 0.0019 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0172 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Loa Loa (eye worm) hypothetical protein 0.0029 0.0134 0.0276
Leishmania major hypothetical protein, conserved 0.0014 0.0045 0.0242
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.001 0.0019 0.5
Loa Loa (eye worm) hypothetical protein 0.0029 0.0134 0.0276
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0027 0.0035
Loa Loa (eye worm) RiNg Finger protein family member 0.0014 0.0045 0.0085
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0027 0.0044
Loa Loa (eye worm) hypothetical protein 0.0033 0.0156 0.0325
Toxoplasma gondii ATPase, AAA family protein 0.001 0.0019 0.0027
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0134 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0019 0.0034
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0115 0.119
Trypanosoma brucei Metacaspase-4 0.0029 0.0134 0.0791
Onchocerca volvulus 0.0014 0.0045 0.0085
Trichomonas vaginalis Sentrin-specific protease, putative 0.0014 0.0045 0.009
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Toxoplasma gondii hypothetical protein 0.0014 0.0045 0.0085
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0279 0.1618 0.3494
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0156 0.015
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0045 0.0422
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0085
Schistosoma mansoni hypothetical protein 0.0279 0.1618 0.3494
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Brugia malayi RNA binding protein 0.0069 0.0373 0.0795
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Brugia malayi Zinc finger, C2H2 type family protein 0.0014 0.0045 0.0085
Plasmodium vivax zinc finger protein, putative 0.0014 0.0045 0.0085
Echinococcus granulosus sentrin specific protease 1 0.0014 0.0045 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0008 0.0006 0.0048
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.0787 0.0782
Echinococcus granulosus zinc finger protein Ran binding 0.0279 0.1618 0.2748
Mycobacterium ulcerans lipase LipD 0.0036 0.0172 1
Treponema pallidum DNA ligase (lig) 0.001 0.0019 0.5
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.007 0.0533
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.0548 0.1175
Loa Loa (eye worm) hypothetical protein 0.0146 0.0826 0.1778
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0172 0.1315
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0008 0.0006 0.0048
Echinococcus granulosus Zinc finger RanBP2 type 0.0279 0.1618 0.2748
Echinococcus granulosus expressed conserved protein 0.0091 0.0504 0.0849
Echinococcus multilocularis dnaJ subfamily B 0.0448 0.2622 0.2618
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Entamoeba histolytica zinc finger domain containing protein 0.0014 0.0045 0.0426
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Leishmania major hypothetical protein, conserved 0.0036 0.0172 0.1031
Onchocerca volvulus 0.0014 0.0045 0.0085
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0279 0.1618 0.2748
Trypanosoma cruzi FHA domain containing protein, putative 0.001 0.0019 0.0078
Brugia malayi hypothetical protein 0.0014 0.0045 0.0085
Brugia malayi steroid hormone receptor 0.0011 0.0027 0.0044
Leishmania major hypothetical protein, conserved 0.0014 0.0045 0.0242
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0045 0.009
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.0019 0.0027
Leishmania major hypothetical protein, conserved 0.0014 0.0045 0.0242
Echinococcus granulosus cpg binding protein 0.0033 0.0159 0.026
Echinococcus multilocularis caspase 0.0109 0.0607 0.0601
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0172 0.0367
Echinococcus granulosus E3 ubiquitin protein ligase LRSAM1 0.0014 0.0045 0.0067
Echinococcus granulosus dnaJ subfamily B 0.0448 0.2622 0.446
Entamoeba histolytica hypothetical protein 0.0039 0.0195 0.2062
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0259 0.0547
Brugia malayi TAR-binding protein 0.0069 0.0373 0.0795
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0.0019 0.0078
Echinococcus multilocularis protein dispatched 1 0.0048 0.0244 0.0238
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0014 0.0045 0.0242
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.1312 1
Echinococcus granulosus ring and YY1 binding protein 0.0279 0.1618 0.2748
Echinococcus multilocularis sentrin specific protease 1 0.0014 0.0045 0.0039
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0134 0.0282
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0259 0.0547
Schistosoma mansoni hypothetical protein 0.0783 0.4618 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0115 0.6556
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Echinococcus granulosus expressed conserved protein 0.0148 0.0838 0.1418
Echinococcus multilocularis expressed conserved protein 0.0148 0.0838 0.0832
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0008 0.0006 0.0048
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0115 0.6556
Plasmodium vivax sentrin-specific protease 2, putative 0.0014 0.0045 0.0084
Entamoeba histolytica dolichyl-diphosphooligosaccharide-protein glycotransferase, putative 0.0049 0.0254 0.2705
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0539 0.5821
Toxoplasma gondii ABC1 family protein 0.0036 0.0172 0.036
Schistosoma mansoni rnf5 0.0014 0.0045 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0134 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0134 0.0282
Loa Loa (eye worm) Ulp1 protease 0.0014 0.0045 0.0084
Echinococcus multilocularis E3 ubiquitin protein ligase LRSAM1 0.0014 0.0045 0.0039
Trichomonas vaginalis sentrin/sumo-specific protease, senp8, putative 0.0014 0.0045 0.009
Brugia malayi hypothetical protein 0.0014 0.0045 0.0085
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0027 0.0035
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0172 0.036
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0027 0.0044
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0172 0.0367
Brugia malayi RING finger protein 20 0.0014 0.0045 0.0085
Echinococcus granulosus ring finger protein 113a 0.0014 0.0045 0.0067
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0045 0.009
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0156 0.0325
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0115 0.0676
Leishmania major DNA repair protein-like protein 0.0014 0.0045 0.0242
Loa Loa (eye worm) hypothetical protein 0.0279 0.1618 0.3494
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0156 0.0325
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0279 0.1618 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0027 0.0044
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.001 0.0019 0.0027
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Loa Loa (eye worm) hypothetical protein 0.0019 0.0076 0.0152
Trypanosoma cruzi metacaspase, putative 0.0029 0.0134 0.0791
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0134 0.0282
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Echinococcus multilocularis ring finger protein 170 0.0014 0.0045 0.0039
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0783 0.4618 1
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0045 0.0242
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0045 0.009
Giardia lamblia Hypothetical protein 0.0014 0.0045 1
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0006 0.0048
Loa Loa (eye worm) hypothetical protein 0.0011 0.0027 0.0044
Entamoeba histolytica hypothetical protein 0.0014 0.0045 0.0426
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0115 0.119
Trypanosoma cruzi metacaspase, putative 0.0029 0.0134 0.0791
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0279 0.1618 0.3494
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0085
Echinococcus multilocularis nibrin 0.001 0.0019 0.0013
Toxoplasma gondii SWI2/SNF2-containing protein RAD5 0.0014 0.0045 0.0085
Loa Loa (eye worm) hypothetical protein 0.0011 0.0027 0.0044
Schistosoma mansoni hypothetical protein 0.0033 0.0156 0.0325
Entamoeba histolytica hypothetical protein 0.0014 0.0045 0.0426
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0085
Schistosoma mansoni brg-1 associated factor 0.0783 0.4618 1
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0134 0.0282
Onchocerca volvulus 0.0279 0.1618 0.3494
Echinococcus granulosus RING finger and transmembrane domain containing protein 0.0014 0.0045 0.0067
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0027 0.0044
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0172 0.0367
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0115 0.6556
Leishmania major hypothetical protein, conserved 0.0279 0.1618 1
Echinococcus granulosus E3 ubiquitin protein ligase Bre1 0.0014 0.0045 0.0067
Plasmodium vivax dolichyl-diphosphooligosaccharide--protein glycosyltransferase, putative 0.0108 0.06 0.1288
Leishmania major hypothetical protein, conserved 0.0014 0.0045 0.0242
Leishmania major hypothetical protein, conserved 0.0014 0.0045 0.0242
Trypanosoma brucei Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Trypanosoma cruzi WLM domain containing protein, putative 0.0279 0.1618 1
Echinococcus granulosus ring finger protein 170 0.0014 0.0045 0.0067
Schistosoma mansoni caspase-7 (C14 family) 0.0029 0.0134 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Loa Loa (eye worm) hypothetical protein 0.0051 0.0265 0.0561
Trypanosoma brucei metacaspase 5, putative 0.0029 0.0134 0.0791
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0172 0.0367
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0027 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0019 0.0078
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0027 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0109 0.0607 0.1024
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Trypanosoma brucei SNF2 family N-terminal domain/Ring finger domain containing protein, putative 0.0014 0.0045 0.0242
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0007 0.0002
Echinococcus granulosus caspase 0.0109 0.0607 0.1024
Loa Loa (eye worm) hypothetical protein 0.0279 0.1618 0.3494
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0027 0.0044
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0195 0.0189
Brugia malayi brahma associated protein 60 kDa 0.0783 0.4618 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Onchocerca volvulus Putative RING finger protein 207 0.0014 0.0045 0.0085
Schistosoma mansoni hypothetical protein 0.004 0.02 0.0421
Entamoeba histolytica hypothetical protein 0.0039 0.0195 0.2062
Schistosoma mansoni hypothetical protein 0.0014 0.0045 0.0085
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0279 0.1618 0.1612
Entamoeba histolytica SPRY domain protein 0.0014 0.0045 0.0426
Loa Loa (eye worm) RING finger protein 20 0.0014 0.0045 0.0085
Chlamydia trachomatis DNA topoisomerase I 0.0783 0.4618 1
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0019 0.0034
Brugia malayi YY1-associated factor 2 0.0279 0.1618 0.3494
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0172 0.1031
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0027 0.0044
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0014 0.0045 0.0084
Echinococcus multilocularis RING finger protein 185 0.0014 0.0045 0.0039
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0027 0.0044
Onchocerca volvulus 0.0014 0.0045 0.0085
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0209 0.044
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0134 0.0276
Entamoeba histolytica zinc finger domain containing protein 0.0014 0.0045 0.0426
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Loa Loa (eye worm) hypothetical protein 0.0011 0.0027 0.0044
Loa Loa (eye worm) hypothetical protein 0.001 0.0019 0.0027
Echinococcus multilocularis zinc finger protein Ran binding 0.0279 0.1618 0.1612
Brugia malayi hypothetical protein 0.001 0.0019 0.0027
Loa Loa (eye worm) hypothetical protein 0.001 0.0019 0.0027
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0014 0.0045 0.0091
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0172 1
Schistosoma mansoni topbp1 0.001 0.0019 0.0027
Echinococcus granulosus sentrin specific protease 8 0.0014 0.0045 0.0066
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0209 0.0346
Leishmania major hypothetical protein, unknown function 0.0014 0.0045 0.0242
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0014 0.0045 0.0085
Onchocerca volvulus 0.0031 0.0148 0.0307
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0029 0.0134 0.0276
Trichomonas vaginalis cell cycle control protein cwf24, putative 0.0014 0.0045 0.0091
Plasmodium vivax DNA repair protein RAD5, putative 0.0014 0.0045 0.0085
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0085
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0027 0.0044
Loa Loa (eye worm) beta-lactamase 0.0036 0.0172 0.036
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0172 0.036
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0007 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0115 0.0878
Mycobacterium tuberculosis Conserved protein 0.0036 0.0172 0.1315
Loa Loa (eye worm) hypothetical protein 0.0036 0.0172 0.036
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0134 0.0282
Brugia malayi nuclear hormone receptor 0.0011 0.0027 0.0044
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0008 0.0006 0.0048
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0008 0.0006 0.0048
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0783 0.4618 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0027 0.002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0172 0.036
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0014 0.0045 0.0091
Brugia malayi Pax transcription activation domain interacting protein 0.001 0.0019 0.0027
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0172 0.036
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0076 0.421
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0109 0.0607 0.0601
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0014 0.0045 0.0084
Leishmania major hypothetical protein, conserved 0.0014 0.0045 0.0242
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0045 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0085
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0076 0.0125
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.007 0.0533
Leishmania major hypothetical protein, conserved 0.0014 0.0045 0.0242
Loa Loa (eye worm) hypothetical protein 0.0036 0.0172 0.036
Onchocerca volvulus 0.0014 0.0045 0.0085
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0085
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0279 0.1618 0.3494
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0014 0.0045 0.024
Echinococcus multilocularis protein patched 0.0042 0.0209 0.0203
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0156 0.0256
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0027 0.0044
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0014 0.0045 0.0091
Trichomonas vaginalis hypothetical protein 0.0014 0.0045 0.0091
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0259 0.043
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0134 0.0282
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0018 0.0026
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0259 0.0547
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0259 0.0547
Echinococcus multilocularis cpg binding protein 0.0033 0.0159 0.0152
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0134 0.0282
Trypanosoma brucei hypothetical protein, conserved 0.0279 0.1618 1
Entamoeba histolytica dolichyl-diphosphooligosaccharide-protein glycotransferase, putative 0.0108 0.06 0.6487
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Brugia malayi hypothetical protein 0.0039 0.0195 0.0409
Trypanosoma cruzi hypothetical protein, conserved 0.0279 0.1618 1
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0019 0.0034
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0027 0.002
Echinococcus multilocularis caspase 8 0.0029 0.0134 0.0127
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0014 0.0045 0.0084
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0014 0.0045 0.0084
Brugia malayi CHE-14 protein 0.0042 0.0209 0.044
Entamoeba histolytica zinc finger domain containing protein 0.0014 0.0045 0.0426
Echinococcus granulosus caspase 2 0.0029 0.0134 0.0217
Giardia lamblia Kinase, NEK 0.0014 0.0045 1
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0014 0.0045 0.0085
Mycobacterium ulcerans hypothetical protein 0.0026 0.0115 0.6556
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0134 0.0276
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Trichomonas vaginalis ankyrin, putative 0.0014 0.0045 0.0091
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0019 0.0034
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0134 0.0282
Trypanosoma brucei metacaspase 0.0029 0.0134 0.0791
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0172 0.1315
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Onchocerca volvulus 0.0026 0.0115 0.0236
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0045 0.0084
Onchocerca volvulus 0.0014 0.0045 0.0085
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0006 0.0048
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0027 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0027 0.0044
Echinococcus multilocularis SWI:SNF matrix associated 0.0783 0.4618 0.4615
Onchocerca volvulus 0.0279 0.1618 0.3494
Plasmodium falciparum sentrin-specific protease 1 0.0014 0.0045 0.0084
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0156 0.0325
Chlamydia trachomatis deubiquitinase/deneddylase Dub2 0.0014 0.0045 0.0057
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Plasmodium vivax sentrin-specific protease 1, putative 0.0014 0.0045 0.0084
Echinococcus granulosus SWI:SNF matrix associated 0.0783 0.4618 0.7864
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0172 0.0367
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0027 0.0044
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0115 0.6556
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0027 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0045 0.0085
Loa Loa (eye worm) hypothetical protein 0.0011 0.0027 0.0044
Echinococcus multilocularis tar DNA binding protein 0.0069 0.0373 0.0367
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0045 0.0242
Schistosoma mansoni topbp1 0.001 0.0019 0.0027
Plasmodium vivax RING zinc finger protein, putative 0.0014 0.0045 0.0085
Schistosoma mansoni hypothetical protein 0.0033 0.0156 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0027 0.0044
Trypanosoma cruzi metacaspase, putative 0.0029 0.0134 0.0791
Schistosoma mansoni RNA binding protein 0.0279 0.1618 0.3494
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.0787 0.1332
Entamoeba histolytica hypothetical protein 0.0039 0.0195 0.2062
Leishmania major hypothetical protein, conserved 0.0279 0.1618 1
Schistosoma mansoni hypothetical protein 0.004 0.02 0.0421
Echinococcus multilocularis sentrin specific protease 8 0.0014 0.0045 0.0039
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0045 0.009
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0279 0.1618 1
Mycobacterium ulcerans hypothetical protein 0.0036 0.0172 1
Entamoeba histolytica hypothetical protein 0.0039 0.0195 0.2062
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Plasmodium falciparum E3 ubiquitin-protein ligase RNF5, putative 0.0014 0.0045 0.0085
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0279 0.1618 1
Giardia lamblia Kinase, NEK 0.0014 0.0045 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0134 0.0276
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0162 0.0922 0.1986
Toxoplasma gondii hypothetical protein 0.0014 0.0045 0.0085
Onchocerca volvulus 0.0279 0.1618 0.3494
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0027 0.0035
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0027 0.0044
Echinococcus granulosus cell growth regulator with ring finger domain 0.0014 0.0045 0.0067
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0027 0.0035
Brugia malayi beta-lactamase family protein 0.0036 0.0172 0.036
Plasmodium vivax trophozoite exported protein 1, putative 0.0014 0.0045 0.0085
Echinococcus granulosus E3 ubiquitin protein ligase RNF146 0.0014 0.0045 0.0067
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0373 0.0795
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0027 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0134 0.0282
Toxoplasma gondii ran binding protein 0.0279 0.1618 0.3494
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Trypanosoma cruzi hypothetical protein, conserved 0.0279 0.1618 1
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0162 0.0922 1
Echinococcus multilocularis replication factor c subunit 1 0.001 0.0019 0.0013
Brugia malayi Zinc finger protein 183 homolog 0.0014 0.0045 0.0085
Loa Loa (eye worm) hypothetical protein 0.0026 0.0115 0.0236
Schistosoma mansoni TRABID protein (C64 family) 0.0279 0.1618 0.3494
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0045 0.0422
Mycobacterium tuberculosis Conserved protein 0.0036 0.0172 0.1315
Brugia malayi hypothetical protein 0.0014 0.0045 0.0085
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0045 0.0242
Schistosoma mansoni peter pan-related 0.0014 0.0045 0.0085
Loa Loa (eye worm) TAR-binding protein 0.0069 0.0373 0.0795
Schistosoma mansoni hypothetical protein 0.0071 0.0383 0.0817
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Onchocerca volvulus 0.0014 0.0045 0.0084
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0027 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0027 0.0044
Echinococcus granulosus nibrin 0.001 0.0019 0.0021
Plasmodium falciparum metacaspase-like protein 0.0029 0.0134 0.0276
Brugia malayi brahma associated protein 60 kDa 0.0783 0.4618 1
Trypanosoma cruzi metacaspase 5, putative 0.0029 0.0134 0.0791
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0007 0.0002
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0783 0.4618 1
Onchocerca volvulus Protein neuralized homolog 0.0014 0.0045 0.0085
Echinococcus granulosus replication factor c subunit 1 0.001 0.0019 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0027 0.0044
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0084
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0019 0.0013
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0115 0.6556
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0014 0.0045 0.0091
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0045 0.009
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0209 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0019 0.0034
Echinococcus multilocularis GPCR, family 2 0.0033 0.0156 0.015
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0373 0.0795
Toxoplasma gondii RING zinc finger protein 0.0014 0.0045 0.0085
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Plasmodium falciparum zinc finger protein, putative 0.0014 0.0045 0.0085
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0027 0.002
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0027 0.0035
Schistosoma mansoni hypothetical protein 0.0014 0.0045 0.0085
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0029 0.0134 0.0276
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0027 0.0044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0259 0.0547
Loa Loa (eye worm) hypothetical protein 0.0019 0.0076 0.0152
Giardia lamblia Hypothetical protein 0.0014 0.0045 1
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Trypanosoma brucei metacaspase MCA2 0.0029 0.0134 0.0791
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0027 0.0044
Schistosoma mansoni fusion 0.0279 0.1618 0.3494
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0027 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0209 0.0203
Onchocerca volvulus 0.0783 0.4618 1
Leishmania major hypothetical protein 0.0014 0.0045 0.0242
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0027 0.0044
Loa Loa (eye worm) brahma associated protein 0.0783 0.4618 1
Trypanosoma cruzi hypothetical protein 0.0014 0.0045 0.024
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0373 0.0795
Echinococcus granulosus RING finger protein 185 0.0014 0.0045 0.0067
Schistosoma mansoni inhibitor of apoptosis 1 diap1 0.0014 0.0045 0.0085
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0045 0.009
Echinococcus granulosus dolichyl diphosphooligosaccharide protein 0.0108 0.06 0.1013
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0027 0.0035
Giardia lamblia E3 ubiquitin ligase for Rad6p required for the ubiquitination of histone H2B 0.0014 0.0045 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0134 0.0282
Schistosoma mansoni cellular tumor antigen P53 0.0146 0.0826 0.1778
Onchocerca volvulus Cell death protein 3 homolog 0.0029 0.0134 0.0276
Brugia malayi ecdysteroid receptor 0.0011 0.0027 0.0044
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0084
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0104 0.0578 0.124
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0172 0.1315
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0085
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0014 0.0045 0.0084
Trypanosoma cruzi WLM domain containing protein, putative 0.0279 0.1618 1
Trichomonas vaginalis antibiotic synthetase, putative 0.0008 0.0006 0.0006
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0045 0.0084
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0007 0.0001
Plasmodium falciparum dolichyl-diphosphooligosaccharide--protein glycosyltransferase, putative 0.0108 0.06 0.1288
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0027 0.0044
Plasmodium falciparum metacaspase 1 0.0029 0.0134 0.0276
Echinococcus granulosus tar DNA binding protein 0.0069 0.0373 0.0626
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0115 0.6556
Trichomonas vaginalis ankyrin, putative 0.0014 0.0045 0.0091
Echinococcus multilocularis E3 ubiquitin protein ligase MYLIP 0.0014 0.0045 0.0039
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0007 0.0001
Brugia malayi Neuralized family protein 0.0014 0.0045 0.0085
Brugia malayi DKFZp564C0469 protein 0.001 0.0019 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Schistosoma mansoni caspase-3 (C14 family) 0.0109 0.0607 0.1302
Onchocerca volvulus 0.001 0.0019 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0019 0.0034
Echinococcus multilocularis ring finger protein 113a 0.0014 0.0045 0.0039
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0027 0.0035
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0045 0.009
Mycobacterium tuberculosis Conserved protein 0.0036 0.0172 0.1315
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0172 0.1031
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0027 0.0044
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0045 0.0422
Loa Loa (eye worm) hypothetical protein 0.001 0.0019 0.0027
Schistosoma mansoni cpg binding protein 0.0031 0.0148 0.0307
Toxoplasma gondii hypothetical protein 0.0014 0.0045 0.0085
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0172 0.1315
Trypanosoma brucei SUMO1/Ulp2, putative 0.0014 0.0045 0.024
Brugia malayi RNA recognition motif domain containing protein 0.0069 0.0373 0.0795
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Trichomonas vaginalis replication factor C large subunit, putative 0.001 0.0019 0.0034
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0027 0.0044
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0014 0.0045 0.0242
Trypanosoma brucei metacaspase MCA3 0.0029 0.0134 0.0791
Loa Loa (eye worm) hypothetical protein 0.0279 0.1618 0.3494
Mycobacterium ulcerans beta-lactamase 0.0036 0.0172 1
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0115 0.0236
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0172 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0076 0.0152
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0783 0.4618 0.7864
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0045 0.0422
Trypanosoma cruzi metacaspase 5, putative 0.0029 0.0134 0.0791
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0172 0.036
Echinococcus granulosus sentrin specific protease 7 0.0162 0.0922 0.1561
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0045 0.0084
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0172 0.036
Brugia malayi Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDasubunit precursor 0.0108 0.06 0.1288
Loa Loa (eye worm) hypothetical protein 0.0036 0.0172 0.036
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0027 0.0044
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0315 0.0669
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0027 0.0035
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0006 0.0048
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0156 0.0256
Giardia lamblia Protein 21.1 0.0014 0.0045 1
Onchocerca volvulus 0.0279 0.1618 0.3494
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0783 0.4618 1
Plasmodium vivax hypothetical protein, conserved 0.0783 0.4618 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0019 0.0027
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0279 0.1618 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Brugia malayi topoisomerase 0.001 0.0019 0.0027
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0084
Schistosoma mansoni hypothetical protein 0.0033 0.0156 0.0325
Brugia malayi beta-lactamase family protein 0.0036 0.0172 0.036
Leishmania major hypothetical protein, conserved 0.0014 0.0045 0.0242
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0279 0.1618 0.3494
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0027 0.0044
Brugia malayi RING zinc finger protein 0.0014 0.0045 0.0085
Schistosoma mansoni hypothetical protein 0.0448 0.2622 0.5672
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Trichomonas vaginalis dolichyl-diphosphooligosaccharide--protein glycosyltransferase, putative 0.0108 0.06 0.1294
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0045 0.0242
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0115 0.0878
Loa Loa (eye worm) hypothetical protein 0.0071 0.0383 0.0817
Plasmodium falciparum replication factor C subunit 1, putative 0.001 0.0019 0.0027
Echinococcus granulosus caspase 8 0.0029 0.0134 0.0217
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0019 0.0034
Plasmodium vivax E3 ubiquitin-protein ligase RNF5, putative 0.0014 0.0045 0.0085
Echinococcus multilocularis SWI:SNF matrix associated 0.0783 0.4618 0.4615
Giardia lamblia Hypothetical protein 0.0014 0.0045 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0006 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0027 0.0035
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Schistosoma mansoni coup transcription factor 0.0011 0.0027 0.0044
Leishmania major hypothetical protein, conserved 0.0014 0.0045 0.0242
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.009
Echinococcus granulosus GPCR family 2 0.0033 0.0156 0.0256
Giardia lamblia Hypothetical protein 0.0014 0.0045 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0027 0.0044
Brugia malayi hypothetical protein 0.0014 0.0045 0.0085
Loa Loa (eye worm) hypothetical protein 0.001 0.0019 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0045 0.0091
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0115 0.119
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0014 0.0045 0.0067
Plasmodium vivax E3 ubiquitin-protein ligase, putative 0.0014 0.0045 0.0085
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0279 0.1618 0.1612
Brugia malayi hypothetical protein 0.0014 0.0045 0.0085
Schistosoma mansoni cpg binding protein 0.0033 0.0159 0.033
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0195 0.0409
Chlamydia trachomatis deubiquitinase/deneddylase Dub1 0.0014 0.0045 0.0057
Schistosoma mansoni caspase-7 (C14 family) 0.0109 0.0607 0.1302

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 82 nM Inhibition of asparagine-linked glycosylation by oligosaccharyl transferase ChEMBL. 10698454

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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