Detailed information for compound 1391647

Basic information

Technical information
  • TDR Targets ID: 1391647
  • Name: ethyl 1-(4-acetamidophenyl)sulfonylpiperidine -3-carboxylate
  • MW: 354.421 | Formula: C16H22N2O5S
  • H donors: 1 H acceptors: 4 LogP: 0.96 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)C1CCCN(C1)S(=O)(=O)c1ccc(cc1)NC(=O)C
  • InChi: 1S/C16H22N2O5S/c1-3-23-16(20)13-5-4-10-18(11-13)24(21,22)15-8-6-14(7-9-15)17-12(2)19/h6-9,13H,3-5,10-11H2,1-2H3,(H,17,19)
  • InChiKey: UNZIWRXTMMZSLN-UHFFFAOYSA-N  

Network

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Synonyms

  • 1-(4-acetamidophenyl)sulfonyl-3-piperidinecarboxylic acid ethyl ester
  • 1-(4-acetamidophenyl)sulfonylnipecotic acid ethyl ester
  • 1-(4-Acetylamino-benzenesulfonyl)-piperidine-3-carboxylic acid ethyl ester
  • BAS 03032674
  • MLS000714521
  • ST5302689
  • SMR000274500
  • EU-0042967
  • Oprea1_189430

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens glucosidase, alpha Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni alpha-glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni alpha-glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Candida albicans closely related to C. albicans GCA1 cell wall mannoprotein glycosyl hydrolase Get druggable targets OG5_127055 All targets in OG5_127055
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Onchocerca volvulus Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Schistosoma japonicum Lysosomal alpha-glucosidase precursor, putative Get druggable targets OG5_127055 All targets in OG5_127055
Loa Loa (eye worm) glycosyl hydrolase family 31 protein Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans cell wall mannoprotein glycosyl hydrolase whose expression increases in presence of galatose Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Glycosyl hydrolases family 31 protein Get druggable targets OG5_127055 All targets in OG5_127055
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans cell wall mannoprotein glycosyl hydrolase whose expression increases in presence of galatose Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans closely related to C. albicans GCA1 cell wall mannoprotein glycosyl hydrolase Get druggable targets OG5_127055 All targets in OG5_127055
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K01187 alpha-glucosidase [EC3.2.1.20], putative Get druggable targets OG5_127055 All targets in OG5_127055
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis p2X purinoceptor 4 0.0131 0.107 0.1034
Brugia malayi hypothetical protein 0.0062 0.0343 0.0992
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.004 0.0127
Toxoplasma gondii transcriptional elongation factor FACT140 0.0048 0.0191 0.0484
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0048 0.0191 0.0605
Echinococcus granulosus RUN 0.0062 0.0343 0.0886
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0092 0.0293
Plasmodium vivax proliferation-associated protein 2g4, putative 0.0048 0.0191 0.0484
Brugia malayi metallopeptidase family M24 containing protein 0.0048 0.0191 0.0553
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0048 0.0191 0.0605
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0102 0.0763 0.221
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0102 0.0322
Echinococcus multilocularis neutral alpha glucosidase AB 0.0079 0.0524 0.0486
Mycobacterium ulcerans hypothetical protein 0.0039 0.0102 0.0031
Trichomonas vaginalis alpha-glucosidase, putative 0.0079 0.0524 0.1662
Echinococcus granulosus FACT complex subunit SPT16 0.0048 0.0191 0.0442
Loa Loa (eye worm) hypothetical protein 0.0039 0.0102 0.0294
Echinococcus multilocularis FACT complex subunit SPT16 0.0048 0.0191 0.0151
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 0.0048 0.0191 0.0605
Onchocerca volvulus 0.0058 0.0302 0.0958
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0102 0.0322
Echinococcus multilocularis Polycystic kidney disease protein 0.0062 0.0343 0.0304
Mycobacterium ulcerans dipeptidase 0.0048 0.0191 0.0337
Schistosoma mansoni hypothetical protein 0.0196 0.1753 0.504
Loa Loa (eye worm) hypothetical protein 0.0039 0.0102 0.0294
Entamoeba histolytica hypothetical protein, conserved 0.0048 0.0191 0.0605
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0092 0.0153
Brugia malayi Glycosyl hydrolases family 31 protein 0.0079 0.0524 0.1518
Brugia malayi Doublecortin family protein 0.0062 0.0343 0.0992
Chlamydia trachomatis methionine aminopeptidase 0.0102 0.0758 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0069 0.0412 0.0374
Schistosoma mansoni aminopeptidase P1 (M24 family) 0.0048 0.0191 0.0444
Brugia malayi metallopeptidase family M24 containing protein 0.0048 0.0191 0.0553
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0102 0.0294
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0102 0.0226
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.1057 0.3062
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.2696 0.7781
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0102 0.0322
Brugia malayi MH2 domain containing protein 0.013 0.1057 0.3062
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0092 0.0053
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0048 0.0191 0.0605
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0079 0.0524 0.1555
Trichomonas vaginalis alpha-glucosidase, putative 0.0079 0.0524 0.1662
Echinococcus multilocularis xaa pro aminopeptidase 0.0048 0.0191 0.0151
Loa Loa (eye worm) hypothetical protein 0.0039 0.0102 0.0294
Echinococcus multilocularis p2X purinoceptor 4 0.0131 0.107 0.1034
Mycobacterium tuberculosis Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) 0.0102 0.0758 0.3113
Schistosoma mansoni alpha-glucosidase 0.0308 0.2929 0.8502
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0079 0.0524 0.1662
Echinococcus granulosus methionyl aminopeptidase 2 0.0329 0.3154 0.9123
Loa Loa (eye worm) transcription factor SMAD2 0.013 0.1057 0.3062
Leishmania major alpha glucosidase II subunit, putative 0.0079 0.0524 0.1662
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0048 0.0191 0.0605
Giardia lamblia Methionine aminopeptidase 0.0329 0.3154 1
Echinococcus granulosus geminin 0.0196 0.1753 0.5018
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0064 0.0204
Loa Loa (eye worm) glutaminase 0.0316 0.3018 0.874
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0102 0.0322
Schistosoma mansoni P2X receptor subunit 0.0131 0.107 0.3031
Echinococcus granulosus p2X purinoceptor 4 0.0131 0.107 0.3017
Echinococcus multilocularis methionyl aminopeptidase 2 0.0329 0.3154 0.3126
Echinococcus granulosus lipoxygenase domain containing protein 0.0062 0.0343 0.0886
Onchocerca volvulus 0.0062 0.0343 0.1086
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0102 0.0062
Schistosoma mansoni hypothetical protein 0.0069 0.0412 0.1096
Echinococcus multilocularis RUN 0.0062 0.0343 0.0304
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0092 0.0293
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0079 0.0524 0.1662
Plasmodium falciparum methionine aminopeptidase 1a, putative 0.0102 0.0758 0.2307
Brugia malayi metallopeptidase family M24 containing protein 0.0048 0.0191 0.0553
Mycobacterium ulcerans lipase LipD 0.0039 0.0102 0.0031
Schistosoma mansoni methionyl aminopeptidase 1 (M24 family) 0.0102 0.0758 0.2114
Toxoplasma gondii methionine aminopeptidase 0.0137 0.1134 0.3513
Loa Loa (eye worm) hypothetical protein 0.0148 0.1252 0.3626
Brugia malayi Latrophilin receptor protein 2 0.0069 0.0412 0.1194
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0102 0.0031
Echinococcus multilocularis lipoxygenase domain containing protein 0.0062 0.0343 0.0304
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0329 0.3154 1
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0102 0.0322
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0461 0.1239
Echinococcus granulosus xaa Pro dipeptidase 0.0048 0.0191 0.0442
Trypanosoma cruzi aminopeptidase P, putative 0.0048 0.0191 0.0605
Schistosoma mansoni inositol monophosphatase 0.0038 0.0092 0.0154
Schistosoma mansoni rab6-interacting 0.0062 0.0343 0.089
Toxoplasma gondii hypothetical protein 0.0036 0.0064 0.0078
Schistosoma mansoni proliferation-associated protein 2G4 38kDa (M24 family) 0.0048 0.0191 0.0444
Schistosoma mansoni alpha glucosidase 0.0079 0.0524 0.1425
Plasmodium vivax FACT complex subunit SPT16, putative 0.0048 0.0191 0.0484
Brugia malayi Glycosyl hydrolases family 31 protein 0.0357 0.3453 1
Echinococcus granulosus p2X purinoceptor 4 0.0131 0.107 0.3017
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0064 0.0204
Trypanosoma cruzi aminopeptidase P1, putative 0.0048 0.0191 0.0605
Loa Loa (eye worm) hypothetical protein 0.0062 0.0343 0.0992
Onchocerca volvulus 0.0062 0.0343 0.1086
Leishmania major aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 0.0048 0.0191 0.0605
Trichomonas vaginalis glutaminase, putative 0.0316 0.3018 0.957
Trichomonas vaginalis esterase, putative 0.0039 0.0102 0.0322
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0102 0.0322
Schistosoma mansoni lipoxygenase 0.0306 0.2914 0.8457
Loa Loa (eye worm) hypothetical protein 0.0033 0.004 0.0116
Loa Loa (eye worm) hypothetical protein 0.0039 0.0102 0.0294
Brugia malayi Importin beta-1 subunit 0.0033 0.004 0.0116
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.004 0.0127
Echinococcus granulosus Xaa Pro aminopeptidase 3 0.0048 0.0191 0.0442
Schistosoma mansoni hypothetical protein 0.0058 0.0302 0.0772
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0069 0.0412 0.0374
Loa Loa (eye worm) initiation factor 2-associated protein 0.0329 0.3154 0.9133
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0461 0.0423
Schistosoma mansoni rab6-interacting 0.0062 0.0343 0.089
Mycobacterium ulcerans dipeptidase PepE 0.0048 0.0191 0.0337
Mycobacterium ulcerans cytoplasmic peptidase PepQ 0.0048 0.0191 0.0337
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0102 0.0226
Plasmodium vivax methionine aminopeptidase 2, putative 0.0329 0.3154 1
Mycobacterium leprae PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) 0.0102 0.0758 1
Brugia malayi RNA, U transporter 1 0.0095 0.0688 0.1991
Echinococcus multilocularis methionyl aminopeptidase 1 (M24 family) 0.0137 0.1134 0.1098
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0329 0.3154 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0102 0.0763 0.2118
Loa Loa (eye worm) hypothetical protein 0.0039 0.0102 0.0294
Loa Loa (eye worm) methionine aminopeptidase type I 0.0137 0.1134 0.3284
Entamoeba histolytica Xaa-Pro dipeptidase, putative 0.0048 0.0191 0.0605
Echinococcus granulosus GPCR family 2 0.0069 0.0412 0.1091
Onchocerca volvulus 0.0039 0.0102 0.0322
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0524 0.1662
Loa Loa (eye worm) inositol-1 0.0038 0.0092 0.0268
Brugia malayi latrophilin 2 splice variant baaae 0.0148 0.1252 0.3626
Brugia malayi glutaminase DH11.1 0.0316 0.3018 0.874
Trypanosoma cruzi Metallopeptidase family M24, putative 0.0048 0.0191 0.0605
Echinococcus multilocularis lysosomal alpha glucosidase 0.0357 0.3453 0.3427
Echinococcus granulosus snurportin 1 0.0356 0.3438 0.9955
Brugia malayi beta-lactamase family protein 0.0039 0.0102 0.0294
Leishmania major aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 0.0048 0.0191 0.0605
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0461 0.1806
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0064 0.0078
Toxoplasma gondii methionine aminopeptidase 2, putative 0.0329 0.3154 1
Trichomonas vaginalis sucrase-isomaltase, putative 0.0079 0.0524 0.1662
Echinococcus granulosus lipoxygenase domain containing protein 0.0062 0.0343 0.0886
Trypanosoma brucei Facilitates chromatin transcription complex subunit spt16 0.0048 0.0191 0.0605
Echinococcus multilocularis methionyl aminopeptidase 1 (M24 family) 0.0102 0.0758 0.0721
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0069 0.0412 0.1194
Schistosoma mansoni hypothetical protein 0.0069 0.0412 0.1096
Echinococcus granulosus xaa pro aminopeptidase 0.0048 0.0191 0.0442
Leishmania major aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 0.0048 0.0191 0.0605
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0048 0.0191 0.0605
Trypanosoma brucei metallo- peptidase, Clan MG, Family M24 0.0137 0.1134 0.3595
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0092 0.0293
Mycobacterium tuberculosis Probable cytoplasmic peptidase PepQ 0.0048 0.0191 0.0619
Plasmodium falciparum methionine aminopeptidase 1c, putative 0.0048 0.0191 0.0484
Schistosoma mansoni lipoxygenase 0.0195 0.1737 0.4994
Schistosoma mansoni hypothetical protein 0.0196 0.1753 0.504
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0069 0.0412 0.1091
Echinococcus granulosus Proliferation associated protein 2G4 0.0048 0.0191 0.0442
Loa Loa (eye worm) latrophilin receptor protein 2 0.0069 0.0412 0.1194
Loa Loa (eye worm) glutaminase 2 0.0316 0.3018 0.874
Toxoplasma gondii ABC1 family protein 0.0039 0.0102 0.0198
Echinococcus granulosus methionine aminopeptidase type I 0.0048 0.0191 0.0442
Mycobacterium tuberculosis Possible penicillin-binding protein 0.025 0.2325 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0461 0.1233
Schistosoma mansoni hypothetical protein 0.0069 0.0412 0.1096
Trypanosoma brucei methionine aminopeptidase, type I, putative 0.0137 0.1134 0.3595
Brugia malayi beta-lactamase family protein 0.0039 0.0102 0.0294
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0102 0.0226
Schistosoma mansoni methionyl aminopeptidase 2 (M24 family) 0.0329 0.3154 0.9164
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0329 0.3154 1
Onchocerca volvulus 0.0039 0.0102 0.0322
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0048 0.0191 0.0605
Plasmodium falciparum methionine aminopeptidase 1b, putative 0.0137 0.1134 0.3513
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0329 0.3154 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0343 0.0992
Trypanosoma brucei Metallopeptidase family M24, putative 0.0048 0.0191 0.0605
Entamoeba histolytica aminopeptidase, putative 0.0048 0.0191 0.0605
Schistosoma mansoni P2X receptor subunit 0.0131 0.107 0.3031
Echinococcus granulosus methionyl aminopeptidase 1 M24 family 0.0137 0.1134 0.3205
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0102 0.0181
Loa Loa (eye worm) doublecortin family protein 0.0062 0.0343 0.0992
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0092 0.0293
Leishmania major hypothetical protein, conserved 0.0036 0.0064 0.0204
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0524 0.1662
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0461 0.1352
Wolbachia endosymbiont of Brugia malayi methionine aminopeptidase 0.0102 0.0758 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0461 0.126
Mycobacterium leprae Probable lipase LipE 0.0039 0.0102 0.0727
Brugia malayi initiation factor 2-associated protein. 0.0329 0.3154 0.9133
Loa Loa (eye worm) hypothetical protein 0.0217 0.1975 0.5721
Plasmodium falciparum aminopeptidase P 0.0048 0.0191 0.0484
Mycobacterium ulcerans methionine aminopeptidase 0.0102 0.0758 0.2276
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0329 0.3154 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0102 0.0763 0.0726
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0079 0.0524 0.1518
Schistosoma mansoni hypothetical protein 0.0148 0.1252 0.3567
Echinococcus multilocularis geminin 0.0196 0.1753 0.1719
Mycobacterium ulcerans aminopeptidase 0.0048 0.0191 0.0337
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0048 0.0191 0.0605
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0102 0.0727
Leishmania major hypothetical protein, conserved 0.0048 0.0191 0.0605
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0329 0.3154 1
Echinococcus multilocularis Proliferation associated protein 2G4 0.0048 0.0191 0.0151
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0302 0.0875
Plasmodium vivax multidomain scavenger receptor, putative 0.0062 0.0343 0.0972
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0102 0.0226
Brugia malayi Inositol-1 0.0038 0.0092 0.0268
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0356 0.3438 0.9956
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0102 0.0763 0.0726
Echinococcus multilocularis xaa Pro dipeptidase 0.0048 0.0191 0.0151
Trypanosoma cruzi Metallopeptidase family M24, putative 0.0048 0.0191 0.0605
Loa Loa (eye worm) DNA-binding protein 0.0048 0.0191 0.0553
Echinococcus granulosus p2X purinoceptor 4 0.0131 0.107 0.3017
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0357 0.3453 1
Onchocerca volvulus 0.0207 0.1866 0.5917
Toxoplasma gondii creatinase domain-containing protein 0.0048 0.0191 0.0484
Mycobacterium tuberculosis Conserved protein 0.0039 0.0102 0.0226
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0102 0.0294
Trypanosoma cruzi metallo- peptidase, Clan MG, Family M24 0.0137 0.1134 0.3595
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0092 0.0293
Leishmania major methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 0.0137 0.1134 0.3595
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0102 0.0763 0.2128
Loa Loa (eye worm) hypothetical protein 0.0048 0.0191 0.0553
Trypanosoma brucei methionine aminopeptidase, putative 0.0137 0.1134 0.3595
Onchocerca volvulus Dipeptidase C homolog 0.0048 0.0191 0.0605
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0092 0.0293
Brugia malayi hypothetical protein 0.0286 0.2696 0.7807
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0092 0.0293
Entamoeba histolytica methionine aminopeptidase, putative 0.0329 0.3154 1
Mycobacterium ulcerans glutaminase 0.0316 0.3018 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0102 0.0763 0.2128
Echinococcus granulosus neutral alpha glucosidase AB 0.0079 0.0524 0.1418
Plasmodium vivax methionine aminopeptidase 1a, putative 0.0102 0.0758 0.2307
Echinococcus multilocularis GPCR, family 2 0.0069 0.0412 0.0374
Trichomonas vaginalis alpha-glucosidase, putative 0.0079 0.0524 0.1662
Mycobacterium tuberculosis Dipeptidase PepE 0.0048 0.0191 0.0619
Echinococcus multilocularis lysosomal alpha glucosidase 0.0357 0.3453 0.3427
Plasmodium falciparum HP12 protein homolog, putative 0.0036 0.0064 0.0078
Schistosoma mansoni glutaminase 0.0316 0.3018 0.8765
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0102 0.018
Plasmodium vivax methionine aminopeptidase 1b, putative 0.0137 0.1134 0.3513
Mycobacterium tuberculosis Conserved protein 0.0039 0.0102 0.0226
Onchocerca volvulus 0.0039 0.0102 0.0322
Schistosoma mansoni alpha-glucosidase 0.0308 0.2929 0.8502
Mycobacterium tuberculosis Conserved protein 0.0039 0.0102 0.0226
Brugia malayi Calcitonin receptor-like protein seb-1 0.0217 0.1975 0.5721
Schistosoma mansoni chromatin-specific transcription elongation factor 140 kDa subunit (M24 family) 0.0048 0.0191 0.0444
Loa Loa (eye worm) hypothetical protein 0.0039 0.0102 0.0294
Leishmania major transcription factor-like protein 0.0048 0.0191 0.0605
Loa Loa (eye worm) beta-lactamase 0.0039 0.0102 0.0294
Loa Loa (eye worm) metallopeptidase family M24 containing protein 0.0048 0.0191 0.0553
Trypanosoma brucei Xaa-Pro aminopeptidase, putative 0.0048 0.0191 0.0605
Treponema pallidum methionine aminopeptidase (map) 0.0102 0.0758 1
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0102 0.0226
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0048 0.0191 0.0605
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0102 0.0763 0.2128
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0102 0.0031
Onchocerca volvulus Methionine aminopeptidase 2 homolog 0.0329 0.3154 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0461 0.1462
Brugia malayi beta-lactamase 0.0039 0.0102 0.0294
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0048 0.0191 0.0605
Mycobacterium leprae Probable cytoplasmic peptidase PepQ 0.0048 0.0191 0.1987
Toxoplasma gondii methionine aminopeptidase 0.0102 0.0758 0.2307
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0064 0.0204
Onchocerca volvulus 0.0048 0.0191 0.0605
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.2696 0.2666
Echinococcus multilocularis snurportin 1 0.0356 0.3438 0.3411
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0102 0.0226
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0102 0.0763 0.221
Wolbachia endosymbiont of Brugia malayi Xaa-Pro aminopeptidase 0.0048 0.0191 0.1479
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0102 0.0322
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0048 0.0191 0.0605
Schistosoma mansoni proliferation-associated protein 2G4 38kDa (M24 family) 0.0048 0.0191 0.0444
Leishmania major hypothetical protein, conserved 0.0039 0.0102 0.0322
Plasmodium falciparum FACT complex subunit SPT16, putative 0.0048 0.0191 0.0484
Trichomonas vaginalis maltase-glucoamylase, putative 0.0079 0.0524 0.1662
Mycobacterium ulcerans beta-lactamase 0.0039 0.0102 0.0031
Loa Loa (eye worm) hypothetical protein 0.0048 0.0191 0.0553
Leishmania major aminopeptidase P, putative,metallo-peptidase, Clan MG, Family M24 0.0048 0.0191 0.0605
Plasmodium vivax peptidase, putative 0.0048 0.0191 0.0484
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0461 0.1239
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0069 0.0412 0.1091
Schistosoma mansoni peptidase 0.0048 0.0191 0.0444
Plasmodium falciparum methionine aminopeptidase 2 0.0329 0.3154 1
Schistosoma mansoni aminopeptidase P homologue (M24 family) 0.0048 0.0191 0.0444
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0461 0.126
Mycobacterium leprae PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) 0.0102 0.0758 1
Entamoeba histolytica peptidase, putative 0.0048 0.0191 0.0605
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0102 0.0226
Trichomonas vaginalis alpha-glucosidase, putative 0.0079 0.0524 0.1662
Echinococcus multilocularis methionine aminopeptidase, type I 0.0048 0.0191 0.0151
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0217 0.1975 0.5721
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0079 0.0524 0.1662
Trichomonas vaginalis alpha-glucosidase, putative 0.0079 0.0524 0.1662
Trypanosoma cruzi Metallopeptidase family M24/FACT complex subunit (SPT16/CDC68)/Histone chaperone Rttp106-like, putative 0.0048 0.0191 0.0605
Loa Loa (eye worm) hypothetical protein 0.0048 0.0191 0.0553
Schistosoma mansoni P2X receptor subunit 0.0131 0.107 0.3031
Echinococcus granulosus lysosomal alpha glucosidase 0.0357 0.3453 1
Plasmodium falciparum proliferation-associated protein 2g4, putative 0.0048 0.0191 0.0484
Echinococcus granulosus Polycystic kidney disease protein 0.0062 0.0343 0.0886
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0217 0.1975 0.5721
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0092 0.0168
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0461 0.126
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0306 0.2914 0.842
Leishmania major methionine aminopeptidase 2, putative 0.0329 0.3154 1
Mycobacterium ulcerans methionine aminopeptidase MapB 0.0102 0.0758 0.2276
Schistosoma mansoni inositol monophosphatase 0.0038 0.0092 0.0154
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0102 0.0181
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0048 0.0191 0.0605
Echinococcus multilocularis Xaa Pro aminopeptidase 3 0.0048 0.0191 0.0151
Plasmodium vivax methionine aminopeptidase 1c, putative 0.0048 0.0191 0.0484
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0306 0.2914 0.2885
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0102 0.0198
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24, putative 0.0048 0.0191 0.0605
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0079 0.0524 0.1662
Schistosoma mansoni survival motor neuron protein 0.0058 0.0302 0.0772
Schistosoma mansoni polycystin 1-related 0.0062 0.0343 0.089
Echinococcus multilocularis p2X purinoceptor 4 0.0131 0.107 0.1034
Toxoplasma gondii methionine aminopeptidase, type i, putative 0.0102 0.0758 0.2307
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0329 0.3154 1
Schistosoma mansoni hypothetical protein 0.0356 0.3438 1
Schistosoma mansoni methionyl aminopeptidase 1 (M24 family) 0.0102 0.0758 0.2114
Mycobacterium tuberculosis Methionine aminopeptidase MapB (map) (peptidase M) 0.0102 0.0758 0.3113
Schistosoma mansoni loxhd1 0.0062 0.0343 0.089
Brugia malayi DNA-binding protein, 42 kDa containing protein 0.0048 0.0191 0.0553
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0048 0.0191 0.0605
Schistosoma mansoni Xaa-Pro dipeptidase (M24 family) 0.0048 0.0191 0.0444
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24, putative 0.0048 0.0191 0.0605
Brugia malayi Methionine aminopeptidase protein type I 0.0137 0.1134 0.3284
Brugia malayi hypothetical protein 0.0062 0.0343 0.0992
Trypanosoma brucei methionine aminopeptidase 2, putative 0.0329 0.3154 1
Schistosoma mansoni hypothetical protein 0.0069 0.0412 0.1096
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0102 0.0322
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0102 0.0763 0.2118
Echinococcus multilocularis xaa Pro dipeptidase 0.0048 0.0191 0.0151
Toxoplasma gondii peptidase D, putative 0.0048 0.0191 0.0484
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0048 0.0191 0.0605
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0092 0.0293
Schistosoma mansoni P2X receptor subunit 0.0131 0.107 0.3031
Echinococcus granulosus xaa Pro dipeptidase 0.0048 0.0191 0.0442
Loa Loa (eye worm) hypothetical protein 0.0069 0.0412 0.1194
Loa Loa (eye worm) hypothetical protein 0.0286 0.2696 0.7807
Trypanosoma cruzi metallo- peptidase, Clan MG, Family M24 0.0137 0.1134 0.3595
Onchocerca volvulus FACT complex subunit SPT16 homolog 0.0048 0.0191 0.0605
Schistosoma mansoni hypothetical protein 0.0062 0.0343 0.089
Trypanosoma brucei glucosidase, putative 0.0079 0.0524 0.1662
Plasmodium falciparum LCCL domain-containing protein 0.0062 0.0343 0.0972
Toxoplasma gondii proliferation-associated protein 2G4, putative 0.0048 0.0191 0.0484
Echinococcus multilocularis lipoxygenase domain containing protein 0.0062 0.0343 0.0304

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.7943 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.5119 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 997 ] ChEMBL. No reference
Potency (functional) = 2.5119 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 1467, 2100, 2112, 1473, 1466 ] ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.99 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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