Detailed information for compound 1392785

Basic information

Technical information
  • TDR Targets ID: 1392785
  • Name: MLS000701726
  • MW: 286.326 | Formula: C16H18N2O3
  • H donors: 0 H acceptors: 2 LogP: 2.92 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)N(C(=O)c1onc2c1CCCC2)C
  • InChi: 1S/C16H18N2O3/c1-18(11-7-9-12(20-2)10-8-11)16(19)15-13-5-3-4-6-14(13)17-21-15/h7-10H,3-6H2,1-2H3
  • InChiKey: NNPASFPMMYOPIJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(4-methoxyphenyl)-N-methyl-4,5,6,7-tetrahydro-2,1-benzisoxazole-3-carboxamide
  • SMR000229934

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens GNAS complex locus Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tumor protein p63 0.035 0.1314 0.1313
Echinococcus granulosus lamin dm0 0.0081 0.0261 0.026
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0038 0.0094 0.0094
Schistosoma mansoni rotamase 0.0033 0.0074 0.0169
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0114 0.0392 0.0392
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0131 0.2818
Echinococcus multilocularis thyroid hormone receptor alpha 0.0291 0.1083 0.1083
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.009 0.0217
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0056 0.0175
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0119 0.0412 0.0411
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0036 0.0084 0.0263
Schistosoma mansoni intermediate filament proteins 0.0081 0.0261 0.0601
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0093 0.3333
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0094 0.0216
Loa Loa (eye worm) TK/ROR protein kinase 0.0022 0.003 0.0096
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0036 0.0084 0.0263
Onchocerca volvulus 0.0018 0.0016 0.0043
Entamoeba histolytica hypothetical protein 0.0037 0.009 0.2405
Echinococcus granulosus nAChR subunit 0.0018 0.0016 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.009 0.0217
Onchocerca volvulus 0.0943 0.3637 1
Brugia malayi nuclear receptor RXR 0.0019 0.0018 0.0057
Echinococcus granulosus cpg binding protein 0.003 0.0062 0.0062
Brugia malayi von Willebrand factor type A domain containing protein 0.0048 0.0131 0.0411
Echinococcus granulosus voltage dependent calcium channel subunit 0.1168 0.4518 0.4517
Echinococcus multilocularis expressed protein 0.0033 0.0074 0.0073
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0017 0.001 0.0009
Brugia malayi Cytochrome P450 family protein 0.0068 0.0211 0.0662
Loa Loa (eye worm) hypothetical protein 0.0079 0.0255 0.08
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.009 0.0089
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0088 0.0212
Echinococcus granulosus histone lysine methyltransferase setb 0.0119 0.0412 0.0411
Schistosoma mansoni nAChR subunit 0.0018 0.0016 0.0035
Echinococcus granulosus glycine receptor subunit beta 0.0018 0.0016 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0036 0.0084 0.0263
Echinococcus granulosus Nuclear hormone receptor HR96 0.0017 0.001 0.0009
Schistosoma mansoni cpg binding protein 0.0028 0.0056 0.0127
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0018 0.0016 0.0049
Mycobacterium ulcerans aldehyde dehydrogenase 0.0245 0.0903 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0036 0.0084 0.0263
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0263
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.0016 0.0035
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0057
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0263
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.006 0.0664
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0017 0.0011 0.0031
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0249 0.0919 0.2122
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0019 0.0018 0.0057
Loa Loa (eye worm) hypothetical protein 0.0038 0.0094 0.0296
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.009 0.0089
Schistosoma mansoni hypothetical protein 0.0014 0.0001 0.0000074312
Schistosoma mansoni hypothetical protein 0.0168 0.0603 0.139
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0373 0.0859
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0065 0.1723
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0036 0.0084 0.0192
Loa Loa (eye worm) hypothetical protein 0.0048 0.0133 0.0418
Schistosoma mansoni survival motor neuron protein 0.0049 0.0134 0.0309
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0036 0.0084 0.0263
Plasmodium falciparum thrombospondin-related anonymous protein 0.0048 0.0131 0.5106
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0028 0.0055 0.0054
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.009 0.1335
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0018 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0032
Brugia malayi EGF-like domain containing protein 0.0048 0.0133 0.0418
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0161 0.0369
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0021 0.002
Schistosoma mansoni DNA helicase recq5 0.0028 0.0055 0.0125
Leishmania major hypothetical protein, conserved 0.0026 0.0046 0.0183
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0048 0.0131 0.0411
Brugia malayi nuclear hormone receptor family member odr-7 0.0017 0.001 0.0032
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0565 0.2156 0.4977
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Schistosoma mansoni nuclear hormone receptor 0.0017 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0152
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0036 0.0084 0.0192
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.0016 0.0049
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0018 0.0016 0.0035
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0161 0.0504
Schistosoma mansoni hypothetical protein 0.0022 0.003 0.0069
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0255 0.0944 0.0943
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0373 0.0996
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0032
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0094 0.0094
Schistosoma mansoni nAChR subunit 0.0018 0.0016 0.0035
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0094 0.0296
Brugia malayi von Willebrand Factor 0.0048 0.0131 0.0411
Loa Loa (eye worm) hypothetical protein 0.0048 0.0131 0.0411
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0018 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0091 0.0286
Onchocerca volvulus 0.0048 0.0131 0.036
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0048 0.0131 0.5106
Schistosoma mansoni zinc finger protein 0.0017 0.001 0.0022
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0021 0.002
Onchocerca volvulus 0.0049 0.0134 0.0369
Loa Loa (eye worm) hypothetical protein 0.0081 0.0261 0.0818
Echinococcus multilocularis glycine receptor subunit beta 0.0018 0.0016 0.0015
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0018 0.0016 0.0049
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0038 0.0094 0.0296
Echinococcus granulosus nuclear receptor nhr 48 0.0017 0.001 0.0009
Brugia malayi 6-phosphofructokinase 0.0109 0.0373 0.1168
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0001 0.0007
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0048 0.0131 0.2818
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0074 0.0235 0.0235
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0094 0.0216
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0032
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.0016 0.0049
Schistosoma mansoni lamin 0.0081 0.0261 0.0601
Loa Loa (eye worm) hypothetical protein 0.0038 0.0094 0.0296
Brugia malayi nuclear receptor RXR 0.0017 0.001 0.0032
Loa Loa (eye worm) doublecortin family protein 0.002 0.0021 0.0065
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0373 0.1168
Echinococcus multilocularis tumor protein p63 0.035 0.1314 0.1313
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0094 0.0094
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0109 0.0373 0.0711
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0373 0.0996
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0088 0.2361
Brugia malayi hypothetical protein 0.0037 0.009 0.0282
Echinococcus multilocularis expressed protein 0.0746 0.2865 0.2865
Brugia malayi hypothetical protein 0.0038 0.0094 0.0296
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0048 0.0131 0.2818
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0036 0.0084 0.0192
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0161 0.016
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0373 1
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0094 0.0216
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0075 0.0237 0.6129
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0097 0.0096
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.009 0.0206
Loa Loa (eye worm) hypothetical protein 0.0048 0.0131 0.0411
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0094 0.0094
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0075 0.0237 0.0742
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0014 0.0001 0.0002
Echinococcus granulosus Nuclear hormone receptor HR96 0.0017 0.001 0.0009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0245 0.0903 1
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0373 0.0859
Schistosoma mansoni lipoxygenase 0.0055 0.0159 0.0365
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0119 0.0412 0.095
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0119 0.0412 0.095
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0057
Trichomonas vaginalis rotamase, putative 0.0033 0.0074 0.0173
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0022 0.003 0.0246
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.0048 0.0131 0.145
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0036 0.0084 0.0083
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0024 0.0039 0.0452
Schistosoma mansoni hypothetical protein 0.0048 0.0131 0.0301
Plasmodium falciparum cysteine repeat modular protein 1 0.0022 0.003 0.0445
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0036 0.0084 0.0263
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0016 0.0049
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.009 0.0206
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0046 0.1231
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0094 0.0216
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0145 0.0333
Brugia malayi hypothetical protein 0.0017 0.0011 0.0036
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.006 0.6181
Brugia malayi Receptor family ligand binding region containing protein 0.0023 0.0033 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0094 0.0228
Onchocerca volvulus Bile acid receptor homolog 0.0036 0.0084 0.0231
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0373 1
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.112 0.4331 1
Brugia malayi steroid hormone receptor 0.0036 0.0084 0.0263
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0088 0.173
Onchocerca volvulus Putative nachr subunit 0.0018 0.0016 0.0043
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0018 0.0016 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0036 0.0084 0.0263
Brugia malayi von Willebrand factor type A domain containing protein 0.0048 0.0131 0.0411
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0016 0.0008 0.0017
Loa Loa (eye worm) hypothetical protein 0.0634 0.2427 0.7609
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0196 0.5252
Loa Loa (eye worm) hypothetical protein 0.0026 0.0046 0.0146
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0036
Toxoplasma gondii kringle domain-containing protein 0.0022 0.003 0.0337
Brugia malayi nuclear receptor NHR-67 0.0017 0.001 0.0032
Onchocerca volvulus 0.0048 0.0131 0.036
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0094 0.0228
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0017 0.001 0.0022
Brugia malayi von Willebrand factor type A domain containing protein 0.0048 0.0131 0.0411
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0055 0.0607
Loa Loa (eye worm) cytochrome P450 family protein 0.0068 0.0211 0.0662
Onchocerca volvulus 0.0017 0.001 0.0028
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0071 0.1891
Brugia malayi hypothetical protein 0.0019 0.0018 0.0057
Brugia malayi laminin alpha chain 0.0048 0.0133 0.0418
Loa Loa (eye worm) PXA domain-containing protein 0.0038 0.0094 0.0296
Schistosoma mansoni hypothetical protein 0.0255 0.0944 0.2178
Brugia malayi Cation transporter family protein 0.0018 0.0016 0.0049
Echinococcus granulosus glycine receptor subunit beta 0.0018 0.0016 0.0015
Brugia malayi hypothetical protein 0.0026 0.0046 0.0146
Entamoeba histolytica hypothetical protein, conserved 0.0048 0.0131 0.3505
Brugia malayi Pre-SET motif family protein 0.0829 0.3189 1
Loa Loa (eye worm) nuclear hormone receptor 0.0017 0.001 0.0032
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0021 0.0066
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0094 0.0094
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.0876 0.0876
Schistosoma mansoni ap endonuclease 0.0037 0.0088 0.0203
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0018 0.0016 0.0015
Echinococcus multilocularis RUN 0.002 0.0021 0.002
Schistosoma mansoni hypothetical protein 0.002 0.0021 0.0047
Echinococcus multilocularis voltage dependent calcium channel subunit 0.2568 1 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0263
Echinococcus multilocularis slit 2 protein 0.0048 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0263
Brugia malayi phosphofructokinase 0.0109 0.0373 0.1168
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.006 0.0134
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0036 0.0084 0.0192
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0017 0.001 0.0022
Echinococcus granulosus pikachurin 0.0048 0.0133 0.0133
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0036 0.0084 0.0083
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0161 0.0369
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0094 0.0216
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0094 0.0216
Onchocerca volvulus 0.0081 0.0261 0.0717
Loa Loa (eye worm) hypothetical protein 0.0039 0.0097 0.0304
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.006 0.0664
Schistosoma mansoni thyroid hormone receptor 0.0291 0.1083 0.25
Onchocerca volvulus 0.0018 0.0016 0.0043
Echinococcus multilocularis nAChR subunit 0.0018 0.0016 0.0015
Brugia malayi 6-phosphofructokinase 0.0109 0.0373 0.1168
Loa Loa (eye worm) hypothetical protein 0.0048 0.0131 0.0411
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0071 0.0786
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0829 0.3189 1
Loa Loa (eye worm) hypothetical protein 0.0517 0.1969 0.6173
Echinococcus multilocularis 6 phosphofructokinase 0.0109 0.0373 0.0372
Mycobacterium ulcerans 6-phosphofructokinase 0.0109 0.0373 0.405
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0196 0.5252
Echinococcus granulosus FTZ F1 alpha 0.0036 0.0084 0.0083
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0081 0.0261 0.0818
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0245 0.0903 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0088 0.3134
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0057
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0017 0.001 0.0032
Chlamydia trachomatis endonuclease IV 0.0075 0.0237 1
Brugia malayi laminin-like protein K08C7.3 precursor 0.0048 0.0133 0.0418
Entamoeba histolytica hypothetical protein 0.0038 0.0094 0.2517
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0028 0.0055 0.0054
Brugia malayi regulator of G-protein signaling egl-10 0.0038 0.0094 0.0296
Loa Loa (eye worm) hypothetical protein 0.0048 0.0131 0.0411
Loa Loa (eye worm) hypothetical protein 0.0048 0.0131 0.0411
Mycobacterium ulcerans aldehyde dehydrogenase 0.0245 0.0903 1
Schistosoma mansoni slit 0.0048 0.0133 0.0306
Brugia malayi Protein kinase domain containing protein 0.0022 0.003 0.0096
Schistosoma mansoni lamin 0.0081 0.0261 0.0601
Onchocerca volvulus 0.0048 0.0131 0.036
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0048 0.0133 0.0306
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0065 0.0147
Toxoplasma gondii exonuclease III APE 0.0037 0.0088 0.098
Loa Loa (eye worm) hypothetical protein 0.0038 0.0091 0.0286
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0159 0.0158
Trichomonas vaginalis DNA helicase recq1, putative 0.004 0.0103 0.0252
Loa Loa (eye worm) hypothetical protein 0.0048 0.0131 0.0411
Brugia malayi ecdysone receptor 0.0017 0.001 0.0032
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0119 0.0412 0.095
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0245 0.0903 1
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0109 0.0372 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0094 0.0228
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.0876 0.0876
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0032
Schistosoma mansoni serine-rich repeat protein 0.0603 0.2306 0.5325
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0036 0.0403
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0071 0.1891
Echinococcus multilocularis cpg binding protein 0.003 0.0062 0.0062
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0094 0.0216
Echinococcus granulosus lamin 0.0081 0.0261 0.026
Brugia malayi Cache domain containing protein 0.0517 0.1969 0.6173
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0088 0.0088
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0088 0.5
Schistosoma mansoni nuclear receptor 0.0017 0.001 0.0022
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.009 0.0089
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0018 0.0016 0.0035
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0094 0.0094
Echinococcus multilocularis lamin 0.0081 0.0261 0.026
Schistosoma mansoni lipoxygenase 0.002 0.0021 0.0047
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0075 0.0237 1
Treponema pallidum methyl-accepting chemotaxis protein (mcp2-1) 0.1351 0.5236 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Brugia malayi follicle stimulating hormone receptor 0.0238 0.0876 0.2746
Schistosoma mansoni ap endonuclease 0.0037 0.0088 0.0203
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.006 0.0134
Echinococcus granulosus ecdysone induced protein 78C 0.0036 0.0084 0.0083
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0018 0.0016 0.0015
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0373 0.0996
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0094 0.0094
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0038 0.0094 0.0228
Schistosoma mansoni hypothetical protein 0.0603 0.2306 0.5325
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0048 0.0131 0.0411
Loa Loa (eye worm) CUTiclin family member 0.0048 0.0131 0.0411
Treponema pallidum 76K protein 0.0048 0.0131 0.0249
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.009 0.0282
Loa Loa (eye worm) RGS-3 protein 0.0038 0.0094 0.0296
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0096
Loa Loa (eye worm) ACC-1 protein 0.0018 0.0016 0.0049
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0036 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0018 0.0016 0.0049
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0036 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0037 0.009 0.0282
Brugia malayi Doublecortin family protein 0.002 0.0021 0.0065
Brugia malayi hypothetical protein 0.0243 0.0897 0.2812
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0249 0.0919 0.2882
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0036 0.0084 0.0263
Giardia lamblia Sgs1 DNA helicase, putative 0.0028 0.0055 0.5526
Entamoeba histolytica hypothetical protein, conserved 0.0048 0.0131 0.3505
Schistosoma mansoni nAChR subunit 0.0018 0.0016 0.0035
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0055 0.0172
Loa Loa (eye worm) hypothetical protein 0.0075 0.0237 0.0742
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0109 0.0373 0.405
Loa Loa (eye worm) intermediate filament protein 0.0081 0.0261 0.0818
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0109 0.0373 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0263
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0119 0.0412 0.4559
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0018 0.0016 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.003 0.0802
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0018 0.0016 0.0015
Brugia malayi Sulfatase family protein 0.0017 0.0011 0.0036
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.009 0.0089
Schistosoma mansoni nAChR subunit 0.0018 0.0016 0.0035
Schistosoma mansoni retinoic acid receptor RXR 0.0036 0.0084 0.0192
Entamoeba histolytica hypothetical protein 0.0038 0.0094 0.2517
Brugia malayi von Willebrand factor type A domain containing protein 0.0048 0.0131 0.0411
Onchocerca volvulus 0.0022 0.003 0.0084
Brugia malayi Kringle domain containing protein 0.0022 0.003 0.0096
Loa Loa (eye worm) hypothetical protein 0.0048 0.0131 0.0411
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Onchocerca volvulus 0.002 0.0021 0.0057
Onchocerca volvulus 0.002 0.0021 0.0057
Echinococcus multilocularis tissue type plasminogen activator 0.0022 0.003 0.003
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0065
Schistosoma mansoni nuclear receptor nhr-48 0.0017 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0105
Schistosoma mansoni nuclear hormone receptor 0.0017 0.001 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0036 0.0084 0.0263
Loa Loa (eye worm) DR-78 0.0017 0.001 0.0032
Echinococcus granulosus Regulator of G protein signaling 20 0.0038 0.0094 0.0094
Echinococcus granulosus beta-adrenergic receptor kinase 0.0038 0.0094 0.0094
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0088 0.9806
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0088 0.0864
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0036 0.0084 0.0083
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0018 0.004
Brugia malayi nuclear hormone receptor 0.0036 0.0084 0.0263
Onchocerca volvulus 0.0081 0.0261 0.0717
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0018 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0048 0.0131 0.0411
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0023 0.0033 0.0105
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0018 0.0057
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0196 0.0195
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0018 0.0016 0.0049
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0065 0.0393
Loa Loa (eye worm) hypothetical protein 0.0048 0.0131 0.0411
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0018 0.0016 0.0049
Echinococcus granulosus bloom syndrome protein 0.004 0.0103 0.0102
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.0016 0.0015
Echinococcus multilocularis dnaJ subfamily B 0.0406 0.1533 0.1533
Toxoplasma gondii aldehyde dehydrogenase 0.0245 0.0903 1
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.009 0.0089
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0017 0.001 0.0032
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0018 0.0016 0.0035
Echinococcus granulosus RUN 0.002 0.0021 0.002
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0094 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0094 0.0228
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0088 0.0212
Onchocerca volvulus 0.0051 0.0145 0.0398
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Onchocerca volvulus 0.0048 0.0131 0.036
Echinococcus multilocularis Regulator of G protein signaling 20 0.0038 0.0094 0.0094
Schistosoma mansoni nuclear hormone receptor 0.0036 0.0084 0.0192
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0018 0.0016 0.0049
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0017 0.001 0.0028
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0048 0.0133 0.0418
Schistosoma mansoni z-protein (S1r protein) 0.0038 0.0094 0.0216
Brugia malayi photoreceptor-specific nuclear receptor 0.0036 0.0084 0.0263
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0088 0.0277
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0018 0.0057
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0036 0.0084 0.0263
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0046 0.1231
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0036 0.0084 0.0263
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0021 0.002
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0804 0.3094 0.3094
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0032
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.0016 0.0015
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0088 0.2361
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0196 0.4586
Entamoeba histolytica hypothetical protein 0.0037 0.009 0.2405
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0036 0.0084 0.0263
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0074 0.0232
Schistosoma mansoni nuclear receptor 0.0017 0.001 0.0022
Schistosoma mansoni nAChR subunit 0.0018 0.0016 0.0035
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0038 0.0094 0.0094
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0161 0.0369
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0065
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0263
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.0016 0.0049
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0071 0.0464
Brugia malayi hypothetical protein 0.002 0.0021 0.0065
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0161 0.016
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0071 0.1891
Brugia malayi hypothetical protein 0.0238 0.0876 0.2747
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0094 0.0216
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0119 0.0412 0.0411
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0094 0.0094
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0161 0.0504
Onchocerca volvulus 0.0018 0.0016 0.0043
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0161 0.016
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0036 0.0084 0.0083
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0094 0.0296
Brugia malayi Zona pellucida-like domain containing protein 0.0048 0.0131 0.0411
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Brugia malayi hypothetical protein 0.0114 0.0393 0.1231
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.009 0.0089
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.001 0.0009
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0094 0.0094
Brugia malayi Bloom's syndrome protein homolog 0.004 0.0103 0.0322
Loa Loa (eye worm) hypothetical protein 0.0051 0.0145 0.0454
Schistosoma mansoni DNA helicase recq1 0.0028 0.0055 0.0125
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0032
Schistosoma mansoni nAChR subunit 0.0018 0.0016 0.0035
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0373 0.0996
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0074 0.0173
Onchocerca volvulus 0.0119 0.0412 0.1132
Echinococcus granulosus expressed protein 0.0033 0.0074 0.0073
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0019 0.0018 0.0017
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0196 0.1897
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0094 0.0094
Schistosoma mansoni metabotropic glutamate receptor 0.0043 0.0114 0.0261
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0032
Schistosoma mansoni thyroid hormone receptor 0.0291 0.1083 0.25
Brugia malayi hypothetical protein 0.0019 0.0018 0.0057
Brugia malayi hypothetical protein 0.0017 0.001 0.0032
Schistosoma mansoni hypothetical protein 0.0037 0.009 0.0207
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0094 0.0216
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0046 0.0654
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0048 0.0131 0.0411
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0065 0.0561
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0088 0.0665
Loa Loa (eye worm) hypothetical protein 0.0048 0.0131 0.0411
Brugia malayi metabotropic glutamate receptor type 2 0.0043 0.0114 0.0356
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0036 0.0084 0.0192
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0134 0.0421
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.006 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0036 0.0084 0.0263
Brugia malayi ecdysteroid receptor 0.0036 0.0084 0.0263
Echinococcus multilocularis bloom syndrome protein 0.004 0.0103 0.0102
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.009 0.0217
Onchocerca volvulus 0.0018 0.0016 0.0043
Schistosoma mansoni RAR-like nuclear receptor 0.0036 0.0084 0.0192
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0263
Echinococcus multilocularis regulator of G protein signaling 0.0038 0.0094 0.0094
Echinococcus granulosus metabotropic glutamate receptor 2 0.0074 0.0235 0.0235
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0075 0.0237 0.2525
Echinococcus granulosus collagen alpha 1VII chain 0.0048 0.0131 0.013
Schistosoma mansoni aldehyde dehydrogenase 0.0245 0.0903 0.2084
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0057
Brugia malayi Intermediate filament tail domain containing protein 0.0081 0.0261 0.0818
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0017 0.001 0.0028
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0109 0.0372 0.1166
Echinococcus granulosus geminin 0.0168 0.0603 0.0602
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0245 0.0903 0.0903
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0036 0.0084 0.0231
Mycobacterium ulcerans endonuclease IV 0.0075 0.0237 0.2525
Brugia malayi excitatory GABA receptor EXP-1A 0.0018 0.0016 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0094 0.0228
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.006 0.0134
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0019 0.0018 0.004
Trichomonas vaginalis DNA helicase recq, putative 0.004 0.0103 0.0252
Schistosoma mansoni hypothetical protein 0.0168 0.0603 0.139
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0065 0.1723
Brugia malayi PXA domain containing protein 0.0038 0.0094 0.0296
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0036 0.0084 0.0263
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0036 0.0084 0.0192
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0032
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0048 0.0131 0.033
Brugia malayi regulator of G-protein signaling rgs-7 0.0038 0.0094 0.0296
Brugia malayi PXA domain containing protein 0.0038 0.0094 0.0296
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0094 0.0216
Echinococcus granulosus metabotropic glutamate receptor 5 0.0109 0.0372 0.0371
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.006 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0036 0.0084 0.0263
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.0016 0.0035
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0032
Echinococcus multilocularis lamin dm0 0.0081 0.0261 0.026
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.0016 0.0015
Echinococcus multilocularis FTZ F1 alpha 0.0036 0.0084 0.0083
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0018 0.0016 0.0049
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.0016 0.0035
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.009 0.2402
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.001 0.0009
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0038 0.0094 0.0296
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0036 0.0084 0.0263
Onchocerca volvulus 0.0036 0.0084 0.0231
Brugia malayi hypothetical protein 0.0038 0.0094 0.0296
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0021 0.0109
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0161 0.016
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0036 0.0084 0.0083
Toxoplasma gondii microneme protein MIC2 0.0048 0.0131 0.145
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0018 0.0016 0.0015
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0018 0.0016 0.0049
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0255 0.0944 0.0943
Brugia malayi conserved hypotetical protein 0.0017 0.001 0.0032
Loa Loa (eye worm) hypothetical protein 0.0048 0.0131 0.0411
Loa Loa (eye worm) glutamate receptor 0.0089 0.0292 0.0915
Echinococcus granulosus transcription factor Dp 1 0.0037 0.009 0.0089
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0017 0.001 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0036 0.0084 0.0263
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Onchocerca volvulus 0.0017 0.001 0.0028
Schistosoma mansoni metabotropic glutamate receptor 0.0074 0.0235 0.0542
Schistosoma mansoni coup transcription factor 0.0036 0.0084 0.0192
Loa Loa (eye worm) CUTiclin-Like family member 0.0048 0.0131 0.0411
Toxoplasma gondii endonuclease IV APN 0.0075 0.0237 0.2619
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0036 0.0084 0.0083
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0094 0.0216
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0057
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0088 0.0168
Echinococcus multilocularis neurogenic locus notch protein 0.0048 0.0133 0.0133
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0088 0.0864
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0018 0.0016 0.0015
Onchocerca volvulus 0.0018 0.0016 0.0043
Echinococcus granulosus leukotriene A 4 hydrolase 0.0249 0.0919 0.0919
Brugia malayi Steroid receptor seven-up type 2 0.0036 0.0084 0.0263
Schistosoma mansoni laminin gamma-3 chain 0.0048 0.0133 0.0306
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0036
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0048 0.0131 0.2818
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.006 0.1001
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0032
Onchocerca volvulus 0.0018 0.0016 0.0043
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0038 0.0094 0.0216
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0016 0.0049
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0036 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0048 0.0131 0.0411
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.009 0.0682
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0114 0.0357
Brugia malayi von Willebrand factor type A domain containing protein 0.0048 0.0131 0.0411
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0018 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0094 0.0296
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0016 0.0049
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0094 0.0094
Echinococcus multilocularis musashi 0.0081 0.0261 0.026
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0046 0.0514
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0016 0.0049
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.006 0.0113
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.009 0.2402
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0196 0.5252
Brugia malayi A-kinase anchor protein 10, precursor 0.0038 0.0094 0.0296
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0028 0.0055 0.0172
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.009 0.0089
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0016 0.0049
Leishmania major ATP-dependent phosphofructokinase 0.0109 0.0373 0.3921
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0021 0.002
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0245 0.0903 0.0903
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0017 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0038 0.0094 0.0296
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0074 0.0232
Echinococcus multilocularis ecdysone induced protein 78C 0.0036 0.0084 0.0083
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0017 0.001 0.0009
Schistosoma mansoni nAChR subunit 0.0018 0.0016 0.0035
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0018 0.0016 0.0015
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0021 0.0058
Brugia malayi hypothetical protein 0.0048 0.0131 0.0411
Schistosoma mansoni hypothetical protein 0.0049 0.0134 0.0309
Entamoeba histolytica hypothetical protein 0.0048 0.0131 0.3505
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.0016 0.0015
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0238 0.0876 0.2746
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0036 0.0084 0.0263
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0075 0.0237 0.5518
Loa Loa (eye worm) hypothetical protein 0.0048 0.0133 0.0418
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0198 0.0456
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Onchocerca volvulus 0.0028 0.0056 0.0153
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0032
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0196 0.0615
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0097 0.0096
Entamoeba histolytica elongation factor-2 kinase, putative 0.0048 0.0131 0.3505
Loa Loa (eye worm) abnormal epIthelia family member 0.0048 0.0133 0.0418
Echinococcus multilocularis glycine receptor subunit beta 0.0018 0.0016 0.0015
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0046 0.1186
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0196 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0094 0.0228
Brugia malayi intermediate filament protein 0.0081 0.0261 0.0818
Onchocerca volvulus Protein ultraspiracle homolog 0.0036 0.0084 0.0231
Brugia malayi hypothetical protein 0.0017 0.001 0.0032
Brugia malayi Cation transporter family protein 0.0018 0.0016 0.0049
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0036 0.0084 0.0083
Schistosoma mansoni loxhd1 0.002 0.0021 0.0047
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0048 0.0131 0.5106
Loa Loa (eye worm) glutamate receptor 0.0035 0.0081 0.0254
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0028 0.0055 0.0054
Schistosoma mansoni hypothetical protein 0.0048 0.0131 0.0301
Brugia malayi Metabotropic glutamate receptor precursor. 0.0089 0.0292 0.0915
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0016 0.0049
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.009 0.0089
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0088 0.0277
Echinococcus granulosus dnaJ subfamily B 0.0406 0.1533 0.1533
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.0046 0.0105
Trichomonas vaginalis rotamase, putative 0.0032 0.0071 0.0164
Brugia malayi Nuclear hormone receptor-like 1 0.0036 0.0084 0.0263
Echinococcus multilocularis pikachurin 0.0048 0.0133 0.0133
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0131 0.0411
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.009 0.2402
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0018 0.0016 0.0015
Echinococcus granulosus thyroid hormone receptor alpha 0.0017 0.001 0.0009
Brugia malayi Zona pellucida-like domain containing protein 0.0048 0.0131 0.0411
Toxoplasma gondii 6-phosphofructokinase 0.003 0.006 0.0664
Loa Loa (eye worm) hypothetical protein 0.0028 0.0055 0.0172
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.006 0.1814
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0018 0.0016 0.0015
Brugia malayi nuclear receptor NHR-88 0.0036 0.0084 0.0263
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0023 0.0033 0.0105
Plasmodium vivax thrombospondin-related anonymous protein 0.0048 0.0131 0.2818
Schistosoma mansoni rab6-interacting 0.002 0.0021 0.0047
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0373 0.1168
Onchocerca volvulus Poor gastrulation protein homolog 0.0014 0.0001 0.0002
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.009 0.0089
Onchocerca volvulus 0.0048 0.0131 0.036
Brugia malayi nuclear receptor NHR-88 0.0017 0.001 0.0032
Loa Loa (eye worm) RecQ helicase 0.004 0.0103 0.0322
Brugia malayi von Willebrand factor type A domain containing protein 0.0048 0.0131 0.0411
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0018 0.0016 0.0015
Onchocerca volvulus 0.0048 0.0131 0.036
Schistosoma mansoni steroid hormone receptor ad4bp 0.0036 0.0084 0.0192
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.006 0.1596
Schistosoma mansoni hypothetical protein 0.0406 0.1533 0.3539
Echinococcus granulosus neurogenic locus notch protein 0.0048 0.0133 0.0133
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.009 0.0207
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0173 0.1912
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.006 0.1814
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0373 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0114 0.0357
Echinococcus granulosus intermediate filament protein 0.0081 0.0261 0.026
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0032
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0018 0.0016 0.0049
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0196 0.0451
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0055 0.0172
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0038 0.0094 0.0296
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0048 0.0131 0.013
Echinococcus multilocularis geminin 0.0168 0.0603 0.0602
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0119 0.0412 0.095
Brugia malayi tailless protein 0.0017 0.001 0.0032
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0088 0.0088
Loa Loa (eye worm) ACC-1 protein 0.0018 0.0016 0.0049
Echinococcus multilocularis nuclear receptor nhr 48 0.0017 0.001 0.0009
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.008 0.0259 0.0812
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0019 0.0018 0.0017
Brugia malayi CXXC zinc finger family protein 0.0028 0.0056 0.0175
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0017 0.001 0.0009
Brugia malayi orphan nuclear receptor NR2E1 0.0017 0.001 0.0032
Brugia malayi Pre-SET motif family protein 0.0119 0.0412 0.1291
Schistosoma mansoni cell polarity protein 0.0048 0.0133 0.0306
Loa Loa (eye worm) nuclear receptor NHR-67 0.0017 0.001 0.0032
Echinococcus granulosus tissue type plasminogen activator 0.0022 0.003 0.003
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0036 0.0084 0.0263
Brugia malayi Nuclear hormone receptor E75 0.0017 0.001 0.0032
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0196 0.0615
Brugia malayi nuclear hormone receptor 0.0017 0.001 0.0032
Brugia malayi Nuclear hormone receptor E75 0.0017 0.001 0.0032
Loa Loa (eye worm) LGC-31 protein 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0048 0.0131 0.0411
Brugia malayi von Willebrand factor type A domain containing protein 0.0048 0.0131 0.0411
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0373 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0094 0.0296
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0028 0.0055 0.0054
Brugia malayi hypothetical protein 0.0017 0.001 0.0032
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0049
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0018 0.0016 0.0049
Echinococcus granulosus slit 2 protein 0.0048 0.0133 0.0133
Entamoeba histolytica hypothetical protein 0.0038 0.0094 0.2517
Mycobacterium ulcerans epimerase 0.002 0.0021 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0263
Schistosoma mansoni rab6-interacting 0.002 0.0021 0.0047
Schistosoma mansoni polycystin 1-related 0.002 0.0021 0.0047
Onchocerca volvulus 0.0048 0.0131 0.036
Loa Loa (eye worm) phosphofructokinase 0.0109 0.0373 0.1168
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0066
Entamoeba histolytica hypothetical protein 0.0037 0.009 0.2405
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0018 0.0016 0.0049
Trichomonas vaginalis set domain proteins, putative 0.0943 0.3637 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.009 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0036 0.0084 0.0083
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0088 0.1289
Echinococcus granulosus expressed protein 0.0746 0.2865 0.2865
Plasmodium vivax SET domain protein, putative 0.0119 0.0412 1
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0018 0.0016 0.0015
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0046 0.1186
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0032
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0055 0.0607
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0159 0.0158
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0088 0.2361
Loa Loa (eye worm) steroid hormone receptor 0.0036 0.0084 0.0263
Schistosoma mansoni cpg binding protein 0.003 0.0062 0.0142
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0071 0.0752
Schistosoma mansoni cpg binding protein 0.003 0.0062 0.0142
Brugia malayi nuclear hormone receptor family member nhr-6 0.0017 0.001 0.0032
Loa Loa (eye worm) hypothetical protein 0.0048 0.0131 0.0411
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0101 0.0339 0.0782
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0036 0.0084 0.0083
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.006 0.0134
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0373 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0036 0.0084 0.0263
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.0016 0.0015
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0038 0.0094 0.0296
Entamoeba histolytica hypothetical protein 0.0037 0.009 0.2405
Treponema pallidum hypothetical protein 0.0048 0.0131 0.0249
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0021 0.0109
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.006 0.1001
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0028 0.0055 0.1576
Mycobacterium ulcerans hypothetical protein 0.002 0.0021 0.0109
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.006 0.0134
Brugia malayi hypothetical protein 0.002 0.0021 0.0065
Echinococcus granulosus 6 phosphofructokinase 0.0109 0.0373 0.0372
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0036 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0119 0.0412 0.1291
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0249 0.0919 0.0919
Loa Loa (eye worm) hypothetical protein 0.0048 0.0133 0.0418
Echinococcus multilocularis voltage dependent calcium channel subunit 0.1168 0.4518 0.4517
Echinococcus multilocularis beta adrenergic receptor kinase 0.0038 0.0094 0.0094
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0014 0.0001 0.0002
Brugia malayi Cation transporter family protein 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0038 0.0094 0.0296
Brugia malayi von Willebrand factor type A domain containing protein 0.0048 0.0131 0.0411
Loa Loa (eye worm) hypothetical protein 0.0238 0.0876 0.2747
Schistosoma mansoni aldehyde dehydrogenase 0.0245 0.0903 0.2084
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0094 0.0094
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0094 0.0094

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 10 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.