Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0034 | 0.004 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0025 | 0.0212 | 0.0527 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0193 | 0.5376 | 0.6332 |
Echinococcus granulosus | chromobox protein 1 | 0.0075 | 0.1742 | 0.1742 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0034 | 0.0484 | 0.0484 |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.0148 | 0.4005 | 0.7418 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0237 | 0.0513 |
Schistosoma mansoni | hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) | 0.0034 | 0.0484 | 0.0891 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0122 | 0.3201 | 0.3201 |
Toxoplasma gondii | hydroxyacylglutathione hydrolase | 0.0034 | 0.0484 | 0.1206 |
Giardia lamblia | Hydroxyacylglutathione hydrolase | 0.0034 | 0.0484 | 0.1206 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0115 | 0.2987 | 0.7458 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0148 | 0.4005 | 0.4717 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0018 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.4122 | 0.4854 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0294 | 0.849 | 1 |
Mycobacterium tuberculosis | Possible hydrolase | 0.0034 | 0.0484 | 0.1204 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0237 | 0.059 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0115 | 0.2987 | 0.7458 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0018 | 0.0001 | 0.0001 |
Mycobacterium ulcerans | hydrolase | 0.0034 | 0.0484 | 0.1138 |
Giardia lamblia | Hydroxyacylglutathione hydrolase | 0.0034 | 0.0484 | 0.1206 |
Echinococcus granulosus | muscleblind protein | 0.0152 | 0.4122 | 0.4122 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0058 | 0.1235 | 0.1235 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0018 | 0.0001 | 0.0001 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0115 | 0.2987 | 0.3518 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0351 | 0.0413 |
Mycobacterium tuberculosis | Possible hydrolase | 0.0034 | 0.0484 | 0.1204 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.4621 | 0.851 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.005 | 0.0982 | 0.1808 |
Schistosoma mansoni | lipoxygenase | 0.0122 | 0.3201 | 0.5896 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0115 | 0.2987 | 0.3518 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0025 | 0.0212 | 0.0249 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0034 | 0.0484 | 0.0891 |
Brugia malayi | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0484 | 0.0569 |
Leishmania major | trypanothione reductase | 0.0038 | 0.062 | 0.1546 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0058 | 0.1235 | 0.3081 |
Schistosoma mansoni | tar DNA-binding protein | 0.0138 | 0.3683 | 0.6783 |
Echinococcus granulosus | zinc phosphodiesterase | 0.0034 | 0.0484 | 0.0484 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0729 | 0.0857 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0484 | 0.0569 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0148 | 0.4005 | 0.4717 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0212 | 0.0249 |
Trypanosoma brucei | trypanothione reductase | 0.0038 | 0.062 | 0.1546 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0018 | 0.0001 | 0.0001 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0058 | 0.1235 | 0.2275 |
Echinococcus multilocularis | zinc phosphodiesterase | 0.0034 | 0.0484 | 0.0484 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0018 | 0.0002 | 0.0003 |
Brugia malayi | Rhodanese-like domain containing protein | 0.0115 | 0.2987 | 0.3518 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0203 | 0.5696 | 0.6709 |
Plasmodium falciparum | thioredoxin reductase | 0.0038 | 0.062 | 0.1474 |
Mycobacterium ulcerans | lipoprotein LpqF | 0.0071 | 0.1618 | 0.4011 |
Mycobacterium ulcerans | hypothetical protein | 0.0034 | 0.0484 | 0.1138 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.0704 | 0.0828 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0034 | 0.0484 | 0.0484 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0115 | 0.2987 | 0.7458 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0034 | 0.0484 | 0.1206 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0148 | 0.4005 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0294 | 0.849 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0194 | 0.543 | 0.543 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0182 | 0.0335 |
Trypanosoma cruzi | metallo-beta-lactamase-like protein, putative | 0.0034 | 0.0484 | 0.1206 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0058 | 0.1235 | 0.304 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.0148 | 0.4005 | 0.4005 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0034 | 0.0484 | 0.1206 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0042 | 0.0729 | 0.1249 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0122 | 0.3201 | 0.3201 |
Mycobacterium leprae | conserved hypothetical protein | 0.0034 | 0.0484 | 0.112 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0103 | 0.0122 |
Brugia malayi | Cytochrome P450 family protein | 0.0046 | 0.0852 | 0.1002 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0148 | 0.4005 | 1 |
Trypanosoma brucei | glyoxalase II | 0.0034 | 0.0484 | 0.1206 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0038 | 0.0593 | 0.0697 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0294 | 0.849 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0138 | 0.3683 | 0.6783 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0084 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0706 | 0.0831 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0065 | 0.0076 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0193 | 0.5376 | 0.6332 |
Mycobacterium leprae | Beta-lactamase-like protein | 0.0034 | 0.0484 | 0.112 |
Mycobacterium tuberculosis | Conserved protein | 0.0034 | 0.0484 | 0.1204 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0148 | 0.4005 | 0.4717 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.002 | 0.0065 | 0.0077 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0088 | 0.2137 | 0.5334 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.0148 | 0.4005 | 0.4005 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0484 | 0.0569 |
Brugia malayi | hypothetical protein | 0.002 | 0.0065 | 0.0076 |
Brugia malayi | ethe1-prov protein | 0.0034 | 0.0484 | 0.0569 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0097 | 0.2438 | 0.6087 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0484 | 0.0569 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.0237 | 0.0513 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.0625 | 0.0625 |
Mycobacterium leprae | PROBABLE CONSERVED LIPOPROTEIN LPQF | 0.0071 | 0.1618 | 0.6275 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0034 | 0.004 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0148 | 0.4005 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0449 | 0.0529 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0138 | 0.3683 | 0.4337 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0237 | 0.059 |
Plasmodium vivax | hydroxyacyl glutathione hydrolase, putative | 0.0034 | 0.0484 | 0.1131 |
Onchocerca volvulus | 0.0034 | 0.0484 | 0.0788 | |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0038 | 0.0593 | 0.0697 |
Toxoplasma gondii | metallo-beta-lactamase domain-containing protein | 0.0034 | 0.0484 | 0.1206 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0193 | 0.5376 | 0.6332 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0038 | 0.062 | 0.1544 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0088 | 0.2137 | 0.5334 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0038 | 0.062 | 0.073 |
Echinococcus multilocularis | geminin | 0.0168 | 0.4621 | 0.4621 |
Brugia malayi | glutathione reductase | 0.0038 | 0.062 | 0.0729 |
Onchocerca volvulus | 0.0115 | 0.2987 | 0.5502 | |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0237 | 0.0513 |
Mycobacterium leprae | conserved hypothetical protein | 0.0034 | 0.0484 | 0.112 |
Trichomonas vaginalis | chromobox protein, putative | 0.0075 | 0.1742 | 0.2052 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0064 | 0.1412 | 0.1412 |
Leishmania major | cleavage and polyadenylation specificity factor, putative | 0.0034 | 0.0484 | 0.1206 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0484 | 0.0569 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0088 | 0.2137 | 0.5334 |
Echinococcus multilocularis | tumor protein p63 | 0.0342 | 1 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0034 | 0.0484 | 0.1204 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0484 | 0.0891 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0025 | 0.0212 | 0.039 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.0484 | 0.1206 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0018 | 0.0001 | 0.0001 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0194 | 0.543 | 0.543 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0034 | 0.0484 | 0.0484 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.0237 | 0.0513 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.271 | 0.3192 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0088 | 0.2137 | 0.5334 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0193 | 0.5376 | 0.6332 |
Echinococcus multilocularis | chromobox protein 1 | 0.0075 | 0.1742 | 0.1742 |
Onchocerca volvulus | 0.0033 | 0.0449 | 0.0723 | |
Loa Loa (eye worm) | hydroxyacylglutathione hydrolase | 0.0034 | 0.0484 | 0.057 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0194 | 0.543 | 0.6395 |
Echinococcus multilocularis | ETHE1 protein | 0.0034 | 0.0484 | 0.0484 |
Leishmania major | hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative | 0.0034 | 0.0484 | 0.1206 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0084 | 0.0154 |
Entamoeba histolytica | alkyl sulfatase, putative | 0.0034 | 0.0484 | 0.1206 |
Schistosoma mansoni | m-phase inducer phosphatase(cdc25) | 0.0115 | 0.2987 | 0.5502 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0097 | 0.2438 | 0.6087 |
Trichomonas vaginalis | m-phase inducer phosphatase, putative | 0.0115 | 0.2987 | 0.3518 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.0237 | 0.0513 |
Mycobacterium leprae | POSSIBLE HYDROLASE | 0.0034 | 0.0484 | 0.112 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0034 | 0.0484 | 0.0891 |
Brugia malayi | chromobox protein homolog 3 | 0.0042 | 0.0729 | 0.0857 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0054 | 0.1114 | 0.1312 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0045 | 0.0827 | 0.1434 |
Onchocerca volvulus | Putative hydrolase PNKD | 0.0034 | 0.0484 | 0.0788 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0194 | 0.543 | 0.6395 |
Schistosoma mansoni | tar DNA-binding protein | 0.0138 | 0.3683 | 0.6783 |
Loa Loa (eye worm) | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0484 | 0.057 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0729 | 0.0858 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0262 | 0.7521 | 0.8858 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0193 | 0.5376 | 0.6332 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0237 | 0.0279 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0252 | 0.7201 | 0.8481 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.0237 | 0.0513 |
Echinococcus multilocularis | hydroxyacylglutathione hydrolase | 0.0034 | 0.0484 | 0.0484 |
Trypanosoma cruzi | glyoxalase II | 0.0034 | 0.0484 | 0.1206 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0064 | 0.1412 | 0.1412 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0294 | 0.849 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0138 | 0.3683 | 0.3683 |
Plasmodium falciparum | cytosolic glyoxalase II | 0.0034 | 0.0484 | 0.1131 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0484 | 0.057 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.0148 | 0.4005 | 0.4005 |
Trypanosoma cruzi | glyoxalase II | 0.0034 | 0.0484 | 0.1206 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0034 | 0.0484 | 0.1206 |
Plasmodium vivax | glutathione reductase, putative | 0.0038 | 0.062 | 0.1474 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0729 | 0.0857 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0038 | 0.062 | 0.1474 |
Onchocerca volvulus | 0.0115 | 0.2987 | 0.5502 | |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0034 | 0.004 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0039 | 0.0635 | 0.0635 |
Brugia malayi | Thioredoxin reductase | 0.0038 | 0.062 | 0.0729 |
Mycobacterium ulcerans | class a beta-lactamase, BlaC | 0.0147 | 0.3984 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0294 | 0.849 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0038 | 0.062 | 0.073 |
Schistosoma mansoni | chromobox protein | 0.0075 | 0.1742 | 0.3209 |
Echinococcus granulosus | serine protein kinase ATM | 0.0025 | 0.0212 | 0.0212 |
Echinococcus granulosus | chromobox protein 1 | 0.0075 | 0.1742 | 0.1742 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0193 | 0.5376 | 0.6332 |
Echinococcus granulosus | geminin | 0.0168 | 0.4621 | 0.4621 |
Mycobacterium ulcerans | Zn-dependent glyoxylase | 0.0034 | 0.0484 | 0.1138 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0034 | 0.0484 | 0.1204 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.271 | 0.3192 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0022 | 0.0103 | 0.0256 |
Loa Loa (eye worm) | RNA binding protein | 0.0138 | 0.3683 | 0.4338 |
Echinococcus granulosus | RUN | 0.002 | 0.0065 | 0.0065 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0484 | 0.0569 |
Brugia malayi | Heterochromatin protein 1 | 0.0075 | 0.1742 | 0.2052 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0034 | 0.0484 | 0.1206 |
Echinococcus multilocularis | tar DNA binding protein | 0.0138 | 0.3683 | 0.3683 |
Brugia malayi | RNA binding protein | 0.0138 | 0.3683 | 0.4337 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.0148 | 0.4005 | 1 |
Entamoeba histolytica | alkyl sulfatase, putative | 0.0034 | 0.0484 | 0.1206 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0193 | 0.5376 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0237 | 0.059 |
Brugia malayi | Doublecortin family protein | 0.002 | 0.0065 | 0.0076 |
Schistosoma mansoni | lipoxygenase | 0.0085 | 0.2068 | 0.3809 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0075 | 0.1742 | 0.2052 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0294 | 0.849 | 1 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.002 | 0.0065 | 0.0065 |
Echinococcus multilocularis | m phase inducer phosphatase(cdc25) | 0.0115 | 0.2987 | 0.2987 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0025 | 0.0212 | 0.0527 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0046 | 0.0852 | 0.1003 |
Onchocerca volvulus | 0.005 | 0.0982 | 0.1726 | |
Wolbachia endosymbiont of Brugia malayi | metallo-beta-lactamase superfamily hydrolase | 0.0034 | 0.0484 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0237 | 0.0279 |
Toxoplasma gondii | thioredoxin reductase | 0.0038 | 0.062 | 0.1546 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.0237 | 0.0513 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0484 | 0.0569 |
Trypanosoma cruzi | metallo-beta-lactamase superfamily, putative | 0.0034 | 0.0484 | 0.1206 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0484 | 0.0569 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0058 | 0.1235 | 0.1235 |
Schistosoma mansoni | tar DNA-binding protein | 0.0138 | 0.3683 | 0.6783 |
Echinococcus granulosus | m phase inducer phosphatasecdc25 | 0.0115 | 0.2987 | 0.2987 |
Schistosoma mansoni | rab6-interacting | 0.002 | 0.0065 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0034 | 0.004 |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.0148 | 0.4005 | 1 |
Plasmodium vivax | RNA helicase-1, putative | 0.0148 | 0.4005 | 1 |
Onchocerca volvulus | Hydroxyacylglutathione hydrolase, mitochondrial homolog | 0.0034 | 0.0484 | 0.0788 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0034 | 0.0484 | 0.0484 |
Trypanosoma brucei | cleavage and polyadenylation specificity factor subunit, putative | 0.0034 | 0.0484 | 0.1206 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0034 | 0.0484 | 0.1206 |
Plasmodium vivax | unspecified product | 0.0034 | 0.0484 | 0.1131 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0148 | 0.4005 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0262 | 0.7521 | 0.8858 |
Trichomonas vaginalis | chromobox protein, putative | 0.0075 | 0.1742 | 0.2052 |
Schistosoma mansoni | tar DNA-binding protein | 0.0138 | 0.3683 | 0.6783 |
Entamoeba histolytica | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0484 | 0.1206 |
Mycobacterium tuberculosis | Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) | 0.0148 | 0.4005 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0038 | 0.062 | 0.1546 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.0148 | 0.4005 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0081 | 0.1919 | 0.2259 |
Trichomonas vaginalis | cdc25b, putative | 0.0115 | 0.2987 | 0.3518 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0018 | 0.0001 | 0.0001 |
Leishmania major | metallo-beta-lactamase family protein-like protein | 0.0034 | 0.0484 | 0.1206 |
Schistosoma mansoni | bromodomain containing protein | 0.0068 | 0.1531 | 0.2819 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.2987 | 0.3518 |
Mycobacterium tuberculosis | Beta lactamase like protein | 0.0034 | 0.0484 | 0.1204 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0212 | 0.0527 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0097 | 0.2438 | 1 |
Echinococcus granulosus | ETHE1 protein | 0.0034 | 0.0484 | 0.0484 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0484 | 0.0891 |
Echinococcus multilocularis | RUN | 0.002 | 0.0065 | 0.0065 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0115 | 0.2987 | 0.3518 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0148 | 0.4005 | 0.7377 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0018 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.4005 | 0.4717 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0484 | 0.057 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0058 | 0.1235 | 0.1454 |
Trypanosoma cruzi | metallo-beta-lactamase superfamily, putative | 0.0034 | 0.0484 | 0.1206 |
Mycobacterium ulcerans | beta lactamase-like protein | 0.0034 | 0.0484 | 0.1138 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0194 | 0.543 | 1 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.002 | 0.0024 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0237 | 0.059 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0138 | 0.3683 | 0.4338 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.002 | 0.0065 | 0.0065 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0034 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0034 | 0.004 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0034 | 0.0484 | 0.1204 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0294 | 0.849 | 1 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0148 | 0.4005 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0484 | 0.057 |
Trichomonas vaginalis | m-phase inducer phosphatase, putative | 0.0115 | 0.2987 | 0.3518 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0484 | 0.0891 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0088 | 0.2137 | 0.8631 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0194 | 0.543 | 0.543 |
Brugia malayi | Rhodanese-like domain containing protein | 0.0115 | 0.2987 | 0.3518 |
Trypanosoma brucei | beta lactamase | 0.0071 | 0.1618 | 0.404 |
Brugia malayi | follicle stimulating hormone receptor | 0.0252 | 0.7201 | 0.8481 |
Loa Loa (eye worm) | hydroxyacylglutathione hydrolase cytoplasmic | 0.0034 | 0.0484 | 0.057 |
Brugia malayi | Muscleblind-like protein | 0.0152 | 0.4122 | 0.4854 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0025 | 0.0212 | 0.0212 |
Brugia malayi | TAR-binding protein | 0.0138 | 0.3683 | 0.4337 |
Brugia malayi | PHD-finger family protein | 0.0027 | 0.026 | 0.0306 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.0237 | 0.0588 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0084 | 0.0084 |
Mycobacterium ulcerans | hypothetical protein | 0.0034 | 0.0484 | 0.1138 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.002 | 0.0065 | 0.0065 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0194 | 0.543 | 0.543 |
Trypanosoma brucei | hydroxyacylglutathione hydrolase, putative | 0.0034 | 0.0484 | 0.1206 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0182 | 0.0182 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0484 | 0.0569 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0848 | 0.0998 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0484 | 0.0569 |
Trypanosoma brucei | metallo-beta-lactamase-like protein, putative | 0.0034 | 0.0484 | 0.1206 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.0237 | 0.0588 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0237 | 0.0278 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.0018 | 0.0002 | 0.0003 |
Mycobacterium ulcerans | hydrolase | 0.0034 | 0.0484 | 0.1138 |
Schistosoma mansoni | polycystin 1-related | 0.002 | 0.0065 | 0.0119 |
Chlamydia trachomatis | ribonuclease Z | 0.0034 | 0.0484 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0058 | 0.1235 | 0.304 |
Mycobacterium tuberculosis | Probable reductase | 0.0088 | 0.2137 | 0.5334 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0018 | 0.0001 | 0.0001 |
Echinococcus multilocularis | chromobox protein 1 | 0.0075 | 0.1742 | 0.1742 |
Trypanosoma cruzi | hydroxyacylglutathione hydrolase, putative | 0.0034 | 0.0484 | 0.1206 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqF | 0.0071 | 0.1618 | 0.4039 |
Trypanosoma cruzi | glyoxalase II | 0.0034 | 0.0484 | 0.1206 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0148 | 0.4005 | 0.7377 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0119 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.2987 | 0.3518 |
Onchocerca volvulus | 0.0026 | 0.0237 | 0.0324 | |
Loa Loa (eye worm) | TAR-binding protein | 0.0138 | 0.3683 | 0.4338 |
Mycobacterium ulcerans | hydrolase | 0.0034 | 0.0484 | 0.1138 |
Onchocerca volvulus | 0.0115 | 0.2987 | 0.5502 | |
Echinococcus granulosus | hydroxyacylglutathione hydrolase | 0.0034 | 0.0484 | 0.0484 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.0237 | 0.059 |
Schistosoma mansoni | rab6-interacting | 0.002 | 0.0065 | 0.0119 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0119 | 0.0218 |
Mycobacterium ulcerans | hypothetical protein | 0.0034 | 0.0484 | 0.1138 |
Treponema pallidum | ATP-dependent RNA helicase | 0.0148 | 0.4005 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0088 | 0.2137 | 0.5334 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0182 | 0.0182 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0097 | 0.2438 | 0.6087 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1777 | 0.2093 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0237 | 0.059 |
Brugia malayi | hypothetical protein | 0.002 | 0.0065 | 0.0076 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.002 | 0.0065 | 0.0065 |
Trypanosoma cruzi | metallo-beta-lactamase-like protein, putative | 0.0034 | 0.0484 | 0.1206 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.4621 | 0.851 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0237 | 0.0278 |
Onchocerca volvulus | 0.0034 | 0.0484 | 0.0788 | |
Echinococcus multilocularis | muscleblind protein | 0.0152 | 0.4122 | 0.4122 |
Plasmodium falciparum | glutathione reductase | 0.0038 | 0.062 | 0.1474 |
Trichomonas vaginalis | chromobox protein, putative | 0.0045 | 0.0827 | 0.0973 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0484 | 0.0569 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0237 | 0.0278 |
Entamoeba histolytica | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0484 | 0.1206 |
Loa Loa (eye worm) | doublecortin family protein | 0.002 | 0.0065 | 0.0076 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0039 | 0.0635 | 0.0635 |
Giardia lamblia | Metallo-beta-lactamase superfamily protein | 0.0034 | 0.0484 | 0.1206 |
Trichomonas vaginalis | A-type flavoprotein | 0.0034 | 0.0484 | 0.0569 |
Schistosoma mansoni | loxhd1 | 0.002 | 0.0065 | 0.0119 |
Mycobacterium ulcerans | glyoxalase II, GloB | 0.0034 | 0.0484 | 0.1138 |
Trypanosoma cruzi | hydroxyacylglutathione hydrolase, putative | 0.0034 | 0.0484 | 0.1206 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0193 | 0.5376 | 0.6332 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0194 | 0.543 | 1 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0484 | 0.0569 |
Toxoplasma gondii | FATC domain-containing protein | 0.0025 | 0.0212 | 0.0527 |
Mycobacterium ulcerans | hypothetical protein | 0.0034 | 0.0484 | 0.1138 |
Trichomonas vaginalis | cdc25b, putative | 0.0115 | 0.2987 | 0.3518 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0065 | 0.0119 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.002 | 0.0065 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0982 | 0.1156 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0237 | 0.0279 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0034 | 0.0484 | 0.1206 |
Trichomonas vaginalis | cdc25c, putative | 0.0115 | 0.2987 | 0.3518 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.002 | 0.0065 | 0.0065 |
Brugia malayi | eukaryotic initiation factor 4A | 0.0148 | 0.4005 | 0.4717 |
Mycobacterium tuberculosis | Conserved protein | 0.0034 | 0.0484 | 0.1204 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.4122 | 0.4854 |
Brugia malayi | Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions Present In The Active Site. | 0.0034 | 0.0484 | 0.0569 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.0625 | 0.0625 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0484 | 0.0569 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0203 | 0.5696 | 0.6709 |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.0148 | 0.4005 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0065 | 0.0076 |
Onchocerca volvulus | 0.0115 | 0.2987 | 0.5502 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0351 | 0.0413 |
Leishmania major | metallo-beta-lactamase family-like protein | 0.0034 | 0.0484 | 0.1206 |
Trichomonas vaginalis | chromobox protein, putative | 0.0045 | 0.0827 | 0.0973 |
Mycobacterium tuberculosis | Class a beta-lactamase BlaC | 0.0147 | 0.3984 | 0.9946 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0152 | 0.4122 | 0.4122 |
Brugia malayi | MH2 domain containing protein | 0.0262 | 0.7521 | 0.8858 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0484 | 0.057 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0784 | 0.0924 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0294 | 0.849 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0194 | 0.543 | 1 |
Brugia malayi | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0484 | 0.0569 |
Plasmodium falciparum | LCCL domain-containing protein | 0.002 | 0.0065 | 0.0077 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0237 | 0.0513 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0034 | 0.0484 | 0.1204 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0484 | 0.0569 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.0148 | 0.4005 | 0.4005 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0058 | 0.1235 | 0.3082 |
Schistosoma mansoni | chromobox protein | 0.0075 | 0.1742 | 0.3209 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.