Detailed information for compound 1623239

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 369.293 | Formula: C18H25BrO3
  • H donors: 0 H acceptors: 2 LogP: 3.83 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: BrCCCOC(=O)C(=C)[C@@H]1CC[C@@H]([C@H]2C(=C(C)C(=O)C2)C1)C
  • InChi: 1S/C18H25BrO3/c1-11-5-6-14(12(2)18(21)22-8-4-7-19)9-16-13(3)17(20)10-15(11)16/h11,14-15H,2,4-10H2,1,3H3/t11-,14+,15-/m0/s1
  • InChiKey: KUNIPSCCVPENGG-GLQYFDAESA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni chromobox protein 0.0012 0.0021 0.0012
Trichomonas vaginalis DNA polymerase eta, putative 0.0085 0.1025 0.1414
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0301 0.0301
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0458 0.0617
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0117 0.0135
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0527 0.7117 1
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0143 0.0172
Trypanosoma cruzi DNA polymerase kappa, putative 0.0085 0.1025 0.2369
Schistosoma mansoni rab6-interacting 0.0021 0.0143 0.0134
Loa Loa (eye worm) CYP4Cod1 0.0021 0.0138 0.0194
Brugia malayi Doublecortin family protein 0.0021 0.0143 0.0188
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0084 0.0105
Mycobacterium leprae conserved hypothetical protein 0.0021 0.015 0.1445
Loa Loa (eye worm) hypothetical protein 0.0013 0.0037 0.0052
Brugia malayi jmjC domain containing protein 0.0017 0.0084 0.0105
Leishmania major DNA damage repair protein, putative 0.0018 0.0095 0.0201
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.0045 0.0045
Brugia malayi hypothetical protein 0.0021 0.0143 0.0188
Schistosoma mansoni brg-1 associated factor 0.0527 0.7117 0.7114
Schistosoma mansoni netrin receptor unc5 0.0015 0.0065 0.0055
Mycobacterium ulcerans DNA polymerase IV 0.0085 0.1025 0.4651
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0936 0.0936
Trichomonas vaginalis DNA helicase recq, putative 0.0033 0.0312 0.0411
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0152 0.1955 0.4541
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0527 0.7117 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0117 0.0135
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.013 0.0153
Echinococcus multilocularis lamin dm0 0.0029 0.025 0.025
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.013 0.0281
Leishmania major hypothetical protein, conserved 0.0187 0.2437 0.5666
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0301 0.0292
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0152 0.1955 0.4541
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0084 0.0084
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.013 0.013
Echinococcus multilocularis dna polymerase kappa 0.0085 0.1025 0.1025
Brugia malayi hypothetical protein 0.0021 0.0143 0.0188
Brugia malayi chromobox protein homolog 3 0.0012 0.0021 0.0016
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0061 0.0697 0.1604
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0143 0.0201
Leishmania major hypothetical protein, conserved 0.0187 0.2437 0.5666
Loa Loa (eye worm) hypothetical protein 0.0031 0.0274 0.0385
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.013 0.0552
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.013 0.0541
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0065 0.0078
Onchocerca volvulus 0.0187 0.2437 0.3405
Echinococcus granulosus ring and YY1 binding protein 0.0187 0.2437 0.2437
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.025 0.0351
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0187 0.2437 0.5666
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0029
Schistosoma mansoni hypothetical protein 0.0015 0.0065 0.0055
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0013 0.0037 0.0052
Echinococcus granulosus dna polymerase kappa 0.0085 0.1025 0.1025
Trypanosoma brucei DNA polymerase eta, putative 0.0084 0.1008 0.2331
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0322 0.4294 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0486 0.1113
Trypanosoma cruzi WLM domain containing protein, putative 0.0187 0.2437 0.5666
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0138 0.0301
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0021 0.0016
Trypanosoma brucei cytochrome P450, putative 0.0021 0.0138 0.0301
Onchocerca volvulus 0.0187 0.2437 0.3405
Schistosoma mansoni TRABID protein (C64 family) 0.0187 0.2437 0.243
Mycobacterium ulcerans DNA polymerase IV 0.0085 0.1025 0.4651
Echinococcus multilocularis zinc finger protein Ran binding 0.0187 0.2437 0.2437
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0068 0.0058
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0031 0.0274 0.0357
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0021 0.0000000002446
Mycobacterium tuberculosis Conserved hypothetical protein 0.017 0.2192 1
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0084 0.0089
Echinococcus multilocularis geminin 0.0181 0.2345 0.2345
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0275 0.0387
Echinococcus granulosus intermediate filament protein 0.0029 0.025 0.025
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0117 0.0135
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0117 0.0135
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0012 0.0021 0.0016
Onchocerca volvulus 0.0108 0.1342 0.1862
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0015 0.006 0.0055
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0143 0.0143
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0031 0.0274 0.0274
Brugia malayi Cytochrome P450 family protein 0.0021 0.0138 0.0181
Entamoeba histolytica deoxycytidyl transferase, putative 0.0057 0.0634 0.763
Echinococcus granulosus dna polymerase eta 0.0084 0.1008 0.1008
Echinococcus granulosus tumor protein p63 0.0329 0.4396 0.4396
Trypanosoma brucei DNA polymerase IV, putative 0.0085 0.1025 0.2369
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0126 0.1587 0.1587
Schistosoma mansoni zinc finger protein 0.0187 0.2437 0.243
Schistosoma mansoni jumonji domain containing protein 0.0063 0.0718 0.0709
Schistosoma mansoni chromobox protein 0.0012 0.0021 0.0012
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0143 0.0143
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0096 0.1175 0.1175
Schistosoma mansoni hypothetical protein 0.0181 0.2345 0.2338
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0084 0.0084
Trypanosoma cruzi hypothetical protein, conserved 0.0187 0.2437 0.5666
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0045 0.047 0.0648
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0096 0.1175 0.1175
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0187 0.2437 0.3405
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.057 0.0802
Schistosoma mansoni lamin 0.0029 0.025 0.0241
Onchocerca volvulus 0.0021 0.0143 0.0172
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0312 0.0707
Echinococcus granulosus chromobox protein 1 0.0012 0.0021 0.0021
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0084 0.0075
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0021 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.1025 0.2369
Trypanosoma brucei unspecified product 0.0078 0.0928 0.2143
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0117 0.0135
Loa Loa (eye worm) hypothetical protein 0.0033 0.0301 0.0423
Echinococcus granulosus lamin dm0 0.0029 0.025 0.025
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0143 0.0143
Echinococcus multilocularis musashi 0.0029 0.025 0.025
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0143 0.0143
Echinococcus multilocularis chromobox protein 1 0.0012 0.0021 0.0021
Brugia malayi Cytochrome P450 family protein 0.0052 0.057 0.0789
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.1025 0.2369
Schistosoma mansoni DNA polymerase eta 0.0084 0.1008 0.1
Brugia malayi brahma associated protein 60 kDa 0.0527 0.7117 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.013 0.0182
Trypanosoma brucei DNA polymerase IV, putative 0.0078 0.0928 0.2143
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0084 0.0084
Plasmodium vivax hypothetical protein, conserved 0.0527 0.7117 1
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0187 0.2437 0.3416
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0084 0.0118
Trypanosoma cruzi hypothetical protein, conserved 0.0187 0.2437 0.5666
Onchocerca volvulus 0.0031 0.0275 0.0359
Leishmania major hypothetical protein, conserved 0.0187 0.2437 0.5666
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0301 0.0292
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0082 0.098 1
Onchocerca volvulus 0.0021 0.0143 0.0172
Brugia malayi CHD4 protein 0.0014 0.0045 0.005
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0021 0.0016
Onchocerca volvulus 0.0029 0.025 0.0323
Trichomonas vaginalis ap endonuclease, putative 0.002 0.013 0.0153
Entamoeba histolytica recQ family helicase, putative 0.0033 0.0312 0.3629
Brugia malayi jmjC domain containing protein 0.0017 0.0084 0.0105
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0057 0.0634 0.0634
Leishmania major cytochrome p450-like protein 0.0021 0.0138 0.0301
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0274 0.0373
Echinococcus multilocularis lamin 0.0029 0.025 0.025
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.047 0.1075
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0322 0.4294 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.1025 0.2369
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0031 0.0274 0.0274
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0082 0.098 0.1366
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0697 0.3149
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0138 0.0301
Echinococcus multilocularis chromobox protein 2 0.0012 0.0021 0.0021
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.013 0.1356
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.098 0.1352
Loa Loa (eye worm) hypothetical protein 0.0021 0.0143 0.0201
Echinococcus multilocularis SWI:SNF matrix associated 0.0527 0.7117 0.7117
Trypanosoma cruzi DNA polymerase kappa, putative 0.0085 0.1025 0.2369
Trypanosoma brucei hypothetical protein, conserved 0.0187 0.2437 0.5666
Trypanosoma brucei hypothetical protein, conserved 0.0187 0.2437 0.5666
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0274 0.0373
Schistosoma mansoni lipoxygenase 0.0126 0.1587 0.158
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0742 0.1043
Schistosoma mansoni hypothetical protein 0.0012 0.0021 0.0012
Toxoplasma gondii hypothetical protein 0.0052 0.0569 0.0788
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0187 0.2437 0.5666
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0066 0.0079
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0117 0.0135
Schistosoma mansoni cpg binding protein 0.0032 0.03 0.0291
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0057 0.0634 0.0634
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0021 0.0016
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.015 0.0197
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0486 0.1113
Schistosoma mansoni hypothetical protein 0.0527 0.7117 0.7114
Schistosoma mansoni chromobox protein 0.0012 0.0021 0.0012
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0068 0.0082
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.013 0.0153
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0021 0.0021
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0084 0.0174
Echinococcus multilocularis tumor protein p63 0.0329 0.4396 0.4396
Echinococcus multilocularis muscleblind protein 1 0.0159 0.205 0.205
Onchocerca volvulus 0.0048 0.0518 0.0701
Trichomonas vaginalis DNA helicase recq1, putative 0.0044 0.0458 0.0617
Plasmodium vivax DNA repair protein REV1, putative 0.0018 0.0095 0.0105
Brugia malayi Muscleblind-like protein 0.0159 0.205 0.2871
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0084 0.0075
Brugia malayi Uncoordinated protein 44 0.0015 0.0065 0.0078
Echinococcus granulosus Chromobox protein 3 0.0012 0.0021 0.0021
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0025 0.0192 0.0258
Brugia malayi jmjC domain containing protein 0.0017 0.0084 0.0105
Loa Loa (eye worm) helicase 0.0012 0.0021 0.0029
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0021 0.0000000021616
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0223 0.2923 0.4107
Echinococcus granulosus chromobox protein 2 0.0012 0.0021 0.0021
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0697 0.0967
Entamoeba histolytica recQ family DNA helicase 0.0016 0.0068 0.0584
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0301 0.0292
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0187 0.2437 0.5666
Onchocerca volvulus 0.0187 0.2437 0.3405
Brugia malayi polk-prov protein 0.0046 0.0486 0.0671
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0095 0.0201
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0478 0.1093
Loa Loa (eye worm) hypothetical protein 0.0015 0.0065 0.0091
Trypanosoma brucei DNA polymerase IV, putative 0.0085 0.1025 0.2369
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0082 0.098 0.4448
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0765 0.0756
Brugia malayi Death domain containing protein 0.0015 0.0065 0.0078
Brugia malayi ImpB/MucB/SamB family protein 0.0084 0.1008 0.1405
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0084 0.0075
Echinococcus multilocularis RUN 0.0021 0.0143 0.0143
Schistosoma mansoni cpg binding protein 0.0031 0.0275 0.0266
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0084 0.0084
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0066 0.0092
Trypanosoma brucei chrX additional, unordered contigs 0.0018 0.0095 0.0201
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0117 0.0135
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0065 0.0065
Loa Loa (eye worm) brahma associated protein 0.0527 0.7117 1
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0527 0.7117 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.0068 0.0136
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0021 0.0016
Mycobacterium ulcerans hypothetical protein 0.017 0.2192 1
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0187 0.2437 0.2437
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.013 0.5
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0084 0.0118
Schistosoma mansoni cpg binding protein 0.0032 0.03 0.0291
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0527 0.7117 0.7117
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0021 0.0000000002446
Echinococcus multilocularis bloom syndrome protein 0.0044 0.0458 0.0458
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0742 0.0733
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0095 0.0201
Loa Loa (eye worm) hypothetical protein 0.0187 0.2437 0.3424
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0021 0.0012
Mycobacterium ulcerans hypothetical protein 0.0018 0.0095 0.0394
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0138 0.0194
Echinococcus granulosus Chromo domain 0.0012 0.0021 0.0021
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0478 0.1093
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0415 0.0415
Echinococcus granulosus zinc finger protein Ran binding 0.0187 0.2437 0.2437
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.013 0.0281
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0029
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0084 0.0084
Echinococcus granulosus phd:f box containing protein 0.0017 0.0084 0.0084
Echinococcus granulosus bloom syndrome protein 0.0044 0.0458 0.0458
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0187 0.2437 0.5666
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0187 0.2437 0.3416
Trypanosoma cruzi WLM domain containing protein, putative 0.0187 0.2437 0.5666
Trypanosoma brucei unspecified product 0.0039 0.0391 0.0892
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0021 0.0000000002446
Brugia malayi SWIB/MDM2 domain containing protein 0.0527 0.7117 1
Schistosoma mansoni hypothetical protein 0.0527 0.7117 0.7114
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0187 0.2437 0.3416
Trypanosoma brucei unspecified product 0.0039 0.0391 0.0892
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0095 0.0201
Mycobacterium ulcerans epimerase 0.0021 0.015 0.0643
Echinococcus multilocularis dna polymerase eta 0.0084 0.1008 0.1008
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0488 0.1118
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0301 0.0301
Brugia malayi Protein cec-1. 0.0012 0.0021 0.0016
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0072 0.0072
Echinococcus multilocularis 0.0011 0.0009 0.0009
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0085 0.1025 0.1414
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0031 0.0274 0.0274
Plasmodium vivax SET domain protein, putative 0.0033 0.0301 0.0395
Giardia lamblia Sgs1 DNA helicase, putative 0.0031 0.0274 0.2814
Brugia malayi SET domain containing protein 0.0014 0.0046 0.0052
Schistosoma mansoni loxhd1 0.0021 0.0143 0.0134
Schistosoma mansoni blooms syndrome DNA helicase 0.0028 0.0244 0.0235
Onchocerca volvulus 0.0108 0.1342 0.1862
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0322 0.4294 1
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0012 0.0021 0.0000000002446
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0084 0.0118
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0057 0.0634 0.0625
Loa Loa (eye worm) hypothetical protein 0.0187 0.2437 0.3424
Loa Loa (eye worm) hypothetical protein 0.0159 0.205 0.288
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0187 0.2437 0.3416
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0095 0.0201
Loa Loa (eye worm) hypothetical protein 0.0108 0.1342 0.1886
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0159 0.205 0.288
Schistosoma mansoni hypothetical protein 0.0187 0.2437 0.243
Schistosoma mansoni chromobox protein 0.0012 0.0021 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0488 0.1118
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0274 0.0373
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0742 0.0742
Brugia malayi YY1-associated factor 2 0.0187 0.2437 0.3416
Trichomonas vaginalis ap endonuclease, putative 0.002 0.013 0.0153
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0824 0.1901
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0045 0.0045
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0084 0.0075
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0187 0.2437 0.5666
Brugia malayi brahma associated protein 60 kDa 0.0527 0.7117 1
Brugia malayi jmjC domain containing protein 0.0064 0.0742 0.1031
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0031 0.0274 0.0385
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.013 0.0552
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0064 0.0731 0.1683
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0095 0.0201
Loa Loa (eye worm) hypothetical protein 0.0082 0.098 0.1377
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0301 0.0301
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0301 0.0411
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0063
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0518 0.0509
Brugia malayi M-phase phosphoprotein, mpp8 0.0108 0.1342 0.1876
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0126 0.1587 0.1587
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0697 0.0697
Toxoplasma gondii exonuclease III APE 0.002 0.013 0.0169
Loa Loa (eye worm) hypothetical protein 0.0017 0.0084 0.0118
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0206 0.0276
Brugia malayi ImpB/MucB/SamB family protein 0.0057 0.0634 0.0878
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.0045 0.0045
Onchocerca volvulus 0.0253 0.3347 0.4688
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0488 0.1118
Trypanosoma cruzi DNA polymerase kappa, putative 0.0085 0.1025 0.2369
Leishmania major mitochondrial DNA polymerase beta 0.0322 0.4294 1
Leishmania major DNA polymerase kappa, putative 0.0064 0.0731 0.1683
Echinococcus granulosus RUN 0.0021 0.0143 0.0143
Echinococcus multilocularis lysine specific demethylase 5A 0.0063 0.0718 0.0718
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.0095 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0072 0.0072
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0021 0.0021
Leishmania major DNA polymerase eta, putative 0.0084 0.1008 0.2331
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.0068 0.0136
Brugia malayi intermediate filament protein 0.0029 0.025 0.0338
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0026 0.0214 0.0272
Brugia malayi jmjC domain containing protein 0.0017 0.0084 0.0105
Schistosoma mansoni RNA binding protein 0.0187 0.2437 0.243
Leishmania major DNA polymerase eta, putative 0.0045 0.047 0.1075
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0527 0.7117 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0057 0.0634 0.089
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0527 0.7117 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.0718 0.0718
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0095 0.0201
Entamoeba histolytica recQ family helicase, putative 0.0015 0.006 0.0482
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0084 0.0075
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0312 0.0707
Loa Loa (eye worm) hypothetical protein 0.0017 0.0084 0.0118
Plasmodium vivax JmjC domain containing protein 0.0017 0.0084 0.0089
Loa Loa (eye worm) hypothetical protein 0.0029 0.025 0.0351
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0824 1
Echinococcus granulosus chromobox protein 1 0.0012 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0527 0.7117 1
Echinococcus multilocularis muscleblind protein 0.0159 0.205 0.205
Brugia malayi Cytochrome P450 family protein 0.0021 0.0138 0.0181
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.064 0.0899
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0731 0.1683
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0084 0.0084
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0021 0.0012
Echinococcus multilocularis SWI:SNF matrix associated 0.0527 0.7117 0.7117
Mycobacterium tuberculosis Conserved hypothetical protein 0.0057 0.0634 0.286
Schistosoma mansoni lamin 0.0029 0.025 0.0241
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0824 0.1901
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0469 0.046
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.015 0.0643
Echinococcus granulosus Zinc finger RanBP2 type 0.0187 0.2437 0.2437
Leishmania major hypothetical protein, conserved 0.0187 0.2437 0.5666
Brugia malayi jmjC domain containing protein 0.0063 0.0718 0.0997
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0478 0.1093
Schistosoma mansoni ap endonuclease 0.002 0.013 0.0121
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0697 0.3149
Schistosoma mansoni DNA polymerase IV / kappa 0.0018 0.0095 0.0086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0252 0.0354
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0824 0.1158
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0061 0.0697 0.0688
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.013 1
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0065 0.0065
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0021 0.0138 0.059
Echinococcus multilocularis Chromo domain 0.0012 0.0021 0.0021
Echinococcus granulosus death domain containing protein 0.0015 0.0065 0.0065
Onchocerca volvulus 0.0187 0.2437 0.3405
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0742 0.0733
Mycobacterium ulcerans endonuclease IV 0.0082 0.098 0.4448
Chlamydia trachomatis DNA topoisomerase I 0.0527 0.7117 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0084 0.0118
Loa Loa (eye worm) heterochromatin protein 1 0.0012 0.0021 0.0029
Schistosoma mansoni intermediate filament proteins 0.0029 0.025 0.0241
Toxoplasma gondii endonuclease IV APN 0.0082 0.098 0.1366
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0824 0.1901
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0669 0.0929
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0276 0.0276
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.1025 0.2369
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.0108 0.0108
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0936 0.0936
Entamoeba histolytica hypothetical protein 0.0012 0.0021 0.0000000021616
Loa Loa (eye worm) hypothetical protein 0.0187 0.2437 0.3424
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0065 0.0055
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0096 0.1175 0.1166
Leishmania major hypothetical protein, conserved 0.0187 0.2437 0.5666
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0095 0.0201
Onchocerca volvulus 0.0527 0.7117 1
Chlamydia trachomatis SWIB complex protein 0.0527 0.7117 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0138 0.0194
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0697 0.0697
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0031 0.0274 0.0274
Echinococcus multilocularis ring and YY1 binding protein 0.0187 0.2437 0.2437
Loa Loa (eye worm) intermediate filament protein 0.0029 0.025 0.0351
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.013 0.0281
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0096 0.1175 0.1166
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.042 0.0563
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0065 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.1025 0.2369
Trypanosoma cruzi DNA polymerase eta, putative 0.0084 0.1008 0.2331
Loa Loa (eye worm) hypothetical protein 0.0084 0.1008 0.1417
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.1025 0.2369
Schistosoma mansoni lipoxygenase 0.0088 0.1066 0.1057
Schistosoma mansoni microtubule-associated protein tau 0.0736 1 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.0614 0.1412
Brugia malayi hypothetical protein 0.0108 0.1344 0.1878
Schistosoma mansoni hypothetical protein 0.0181 0.2345 0.2338
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0312 0.0707
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0274 0.0373
Brugia malayi Heterochromatin protein 1 0.0012 0.0021 0.0016
Schistosoma mansoni hypothetical protein 0.0021 0.0143 0.0134
Trypanosoma cruzi DNA polymerase kappa, putative 0.0085 0.1025 0.2369
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0527 0.7117 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.013 0.0281
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0064 0.0731 0.3304
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.013 0.0169
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0187 0.2437 0.5666
Echinococcus granulosus muscleblind protein 0.0159 0.205 0.205
Echinococcus granulosus Ankyrin 0.0015 0.0066 0.0066
Brugia malayi Bloom's syndrome protein homolog 0.0044 0.0458 0.0632
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0478 0.1093
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0117 0.0135
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0527 0.7117 0.7117
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0045 0.0045
Schistosoma mansoni polycystin 1-related 0.0021 0.0143 0.0134
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0143 0.0143
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0021 0.0000000002446
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0084 0.0174
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0187 0.2437 0.3424
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0021 0.0000000021616
Trichomonas vaginalis set domain proteins, putative 0.0253 0.3345 0.4685
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0187 0.2437 0.3405
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0824 0.1901
Echinococcus multilocularis cpg binding protein 0.0032 0.03 0.03
Trypanosoma cruzi hypothetical protein, conserved 0.0187 0.2437 0.5666
Loa Loa (eye worm) hypothetical protein 0.0108 0.1344 0.1889
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.098 0.1352
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0084 0.0105
Plasmodium falciparum DNA repair protein REV1, putative 0.0018 0.0095 0.0105
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0824 0.0824
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0415 0.0415
Echinococcus granulosus cytochrome P450 2K1 0.0011 0.0009 0.0009
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0095 0.0201
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0065 0.0091
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0187 0.2437 0.2437
Leishmania major hypothetical protein, conserved 0.0017 0.0084 0.0174
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.1025 0.2369
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.1025 0.2369
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0187 0.2437 0.3424
Echinococcus granulosus SWI:SNF matrix associated 0.0527 0.7117 0.7117
Schistosoma mansoni terminal deoxycytidyl transferase 0.0057 0.0634 0.0625
Echinococcus multilocularis microtubule associated protein 2 0.0736 1 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.015 0.021
Echinococcus granulosus lamin 0.0029 0.025 0.025
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0021 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0029
Brugia malayi Pre-SET motif family protein 0.0033 0.0301 0.0411
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0084 0.0174
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0187 0.2437 0.3416
Loa Loa (eye worm) hypothetical protein 0.0048 0.0518 0.0728
Giardia lamblia DINP protein human, muc B family 0.0064 0.0731 1
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.015 0.0181
Onchocerca volvulus 0.0045 0.0469 0.0632
Schistosoma mansoni rab6-interacting 0.0021 0.0143 0.0134
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0066 0.0057
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0187 0.2437 0.5666
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0824 0.0824
Toxoplasma gondii ran binding protein 0.0187 0.2437 0.3416
Loa Loa (eye worm) hypothetical protein 0.0016 0.0068 0.0095
Brugia malayi Pre-SET motif family protein 0.0223 0.2923 0.4099
Echinococcus granulosus geminin 0.0181 0.2345 0.2345
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0824 0.1146
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0065 0.0062
Echinococcus granulosus cpg binding protein 0.0032 0.03 0.03
Loa Loa (eye worm) RecQ helicase 0.0044 0.0458 0.0644
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.0718 0.0718
Echinococcus multilocularis SWI:SNF matrix associated 0.0527 0.7117 0.7117
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0021 0.0016
Brugia malayi CXXC zinc finger family protein 0.0031 0.0275 0.0374
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.0108 0.0108
Echinococcus multilocularis chromobox protein 1 0.0012 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0015 0.0066 0.0093
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0187 0.2437 0.2437
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0021 0.0000000021616
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0143 0.0172
Echinococcus multilocularis Ankyrin 0.0015 0.0066 0.0066
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.025 0.0338
Loa Loa (eye worm) cytochrome P450 0.0011 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0029
Leishmania major DNA polymerase kappa, putative 0.0018 0.0095 0.0201
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.013 0.013
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0152 0.1955 0.4541
Loa Loa (eye worm) hypothetical protein 0.0021 0.0143 0.0201
Schistosoma mansoni DNA helicase recq5 0.0031 0.0274 0.0265
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0824 0.0815
Loa Loa (eye worm) hypothetical protein 0.0028 0.0242 0.0341
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0061 0.0697 0.3149
Schistosoma mansoni hypothetical protein 0.0527 0.7117 0.7114
Mycobacterium ulcerans hypothetical protein 0.0021 0.015 0.0643
Schistosoma mansoni ap endonuclease 0.002 0.013 0.0121
Schistosoma mansoni fusion 0.0187 0.2437 0.243
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.1025 0.2369
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0045 0.0063
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.015 0.0643
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0029
Schistosoma mansoni DNA helicase recq1 0.0031 0.0274 0.0265
Loa Loa (eye worm) hypothetical protein 0.0046 0.0486 0.0683
Onchocerca volvulus 0.0029 0.025 0.0323
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0045 0.0036
Brugia malayi Protein kinase domain containing protein 0.0015 0.0065 0.0078

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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