Detailed information for compound 1713898

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 532.652 | Formula: C26H36N4O6S
  • H donors: 3 H acceptors: 5 LogP: 2.38 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC[C@H](N1C[C@@H](C)[C@@H](CN(C(=O)NC(C)C)C)Oc2c(C1=O)cc(cc2)NS(=O)(=O)c1ccccc1)C
  • InChi: 1S/C26H36N4O6S/c1-17(2)27-26(33)29(5)15-24-18(3)14-30(19(4)16-31)25(32)22-13-20(11-12-23(22)36-24)28-37(34,35)21-9-7-6-8-10-21/h6-13,17-19,24,28,31H,14-16H2,1-5H3,(H,27,33)/t18-,19-,24-/m1/s1
  • InChiKey: TZVATHBZTZBTQC-KHCICDEESA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi kap beta 3 protein 0.0011 0.0023 0.0037
Echinococcus multilocularis snurportin 1 0.0631 0.8386 0.8386
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0045 0.0482 0.1027
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0186 0.0607
Echinococcus multilocularis translational activator gcn1 0.0011 0.0023 0.0023
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0045 0.0482 0.0926
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0186 0.0607
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0103 0.1258 0.1258
Mycobacterium ulcerans acetylornithine aminotransferase 0.0045 0.0482 0.1027
Mycobacterium ulcerans hypothetical protein 0.0021 0.0153 0.0225
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0103 0.1255 0.283
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0092 0.1116 0.2571
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0519 0.1197
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0014 0.0061 0.0142
Echinococcus granulosus transportin 1 0.0011 0.0023 0.0023
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.02 0.0548
Schistosoma mansoni ferritin light chain 0.0017 0.0106 0.0084
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0023 0.0181 0.053
Brugia malayi CXXC zinc finger family protein 0.0031 0.0286 0.086
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0186 0.1324
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0064 0.0738 0.2272
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0186 0.0607
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0012 0.0027 0.0017
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0061 0.0142
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.1146 0.3547
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0186 0.0607
Entamoeba histolytica acyl-CoA synthetase, putative 0.0021 0.0153 0.1057
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0044 0.0459 0.312
Mycobacterium tuberculosis Conserved protein 0.0024 0.02 0.0338
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0044 0.0459 0.312
Loa Loa (eye worm) hypothetical protein 0.0039 0.0402 0.0479
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0032 0.0298 0.0298
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0064 0.0738 0.0738
Schistosoma mansoni tar DNA-binding protein 0.0193 0.2471 0.2454
Loa Loa (eye worm) hypothetical protein 0.0026 0.0222 0.0265
Trichomonas vaginalis mercuric reductase, putative 0.0014 0.0061 0.0092
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.2717 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0061 0.0142
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0044 0.0044
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0203 0.2609 0.8116
Echinococcus multilocularis zinc finger protein 0.0019 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0023 0.0186 0.0222
Brugia malayi TAR-binding protein 0.0193 0.2471 0.7685
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1146 0.1126
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0186 0.0186
Echinococcus granulosus snurportin 1 0.0631 0.8386 0.8386
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0519 0.1197
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0348 0.0786
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0153 0.0445
Brugia malayi Importin beta-1 subunit 0.0059 0.0669 0.2057
Trypanosoma cruzi trypanothione reductase, putative 0.0014 0.0061 0.0028
Echinococcus multilocularis dna polymerase eta 0.0023 0.0186 0.0186
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0459 0.1522
Schistosoma mansoni hypothetical protein 0.0064 0.0738 0.0717
Plasmodium vivax ornithine aminotransferase, putative 0.0045 0.0482 0.3288
Leishmania major DNA polymerase kappa, putative 0.0023 0.0186 0.0607
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0186 0.0607
Schistosoma mansoni DNA polymerase eta 0.0023 0.0186 0.0164
Mycobacterium ulcerans hypothetical protein 0.0024 0.02 0.0338
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0064 0.0738 0.0738
Schistosoma mansoni cpg binding protein 0.0034 0.0332 0.031
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0115 0.1421 0.5189
Schistosoma mansoni tar DNA-binding protein 0.0193 0.2471 0.2454
Onchocerca volvulus 0.0026 0.0229 0.0684
Brugia malayi beta-lactamase 0.0035 0.0348 0.1055
Echinococcus granulosus Aminotransferase class III 0.0045 0.0482 0.0482
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0459 0.1522
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0016 0.0083 0.0061
Echinococcus granulosus leucyl aminopeptidase 0.0023 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0035 0.0348 0.0415
Echinococcus multilocularis tar DNA binding protein 0.0193 0.2471 0.2471
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0054 0.0604 0.0604
Leishmania major hypothetical protein, conserved 0.0211 0.2717 1
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0045 0.0482 0.0926
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0023 0.0181 0.053
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1146 0.1126
Brugia malayi follicle stimulating hormone receptor 0.0248 0.3212 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0014 0.0061 0.0142
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0014 0.0061 0.0038
Echinococcus granulosus importin subunit beta 1 0.0059 0.0669 0.0669
Toxoplasma gondii thioredoxin reductase 0.004 0.0417 0.2824
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0092 0.1116 0.2571
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0045 0.0482 0.1027
Echinococcus multilocularis importin subunit beta 1 0.0059 0.0669 0.0669
Plasmodium vivax thioredoxin reductase, putative 0.004 0.0417 0.2824
Treponema pallidum bacterioferrin (TpF1) 0.0017 0.0106 1
Entamoeba histolytica Ran family GTPase 0.0044 0.0459 0.353
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0186 0.0305
Brugia malayi beta-lactamase family protein 0.0035 0.0348 0.1055
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0348 0.0596
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0045 0.0482 0.1027
Schistosoma mansoni ferritin 0.0017 0.0106 0.0084
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0318 0.4167 1
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0229 0.0681
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0092 0.1116 0.2488
Mycobacterium ulcerans lipase LipD 0.0035 0.0348 0.07
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0186 0.0607
Brugia malayi Thioredoxin reductase 0.004 0.0417 0.127
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0014 0.0061 0.0142
Loa Loa (eye worm) importin-beta domain-containing protein 0.0011 0.0023 0.0027
Loa Loa (eye worm) hypothetical protein 0.0016 0.0082 0.0098
Giardia lamblia DINP protein human, muc B family 0.0023 0.0186 0.1047
Onchocerca volvulus 0.0026 0.0229 0.0684
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1258 0.2982
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0186 0.0607
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0061 0.0028
Loa Loa (eye worm) hypothetical protein 0.0016 0.0082 0.0098
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0064 0.0738 0.0738
Echinococcus granulosus ferritin 0.0017 0.0106 0.0106
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.004 0.0417 0.0868
Echinococcus multilocularis leucyl aminopeptidase 0.0023 0.0181 0.0181
Mycobacterium ulcerans beta-lactamase 0.0035 0.0348 0.07
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0153 0.0445
Plasmodium vivax glutathione reductase, putative 0.004 0.0417 0.2824
Toxoplasma gondii ABC1 family protein 0.0035 0.0348 0.233
Entamoeba histolytica acyl-CoA synthetase, putative 0.0021 0.0153 0.1057
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0348 0.0326
Loa Loa (eye worm) hypothetical protein 0.0139 0.1743 0.2079
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0092 0.1116 0.2571
Loa Loa (eye worm) hypothetical protein 0.0034 0.0327 0.039
Brugia malayi RNA recognition motif domain containing protein 0.0193 0.2471 0.7685
Loa Loa (eye worm) RNA binding protein 0.0193 0.2471 0.2947
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0115 0.1421 0.5189
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0186 0.0607
Echinococcus multilocularis leucine aminopeptidase protein 0.0115 0.1421 0.1421
Schistosoma mansoni ferritin 0.0017 0.0106 0.0084
Plasmodium falciparum importin beta, putative 0.0059 0.0669 0.4626
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0348 0.233
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0115 0.1421 1
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0115 0.1421 0.3237
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0348 0.0326
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0014 0.0061 0.0273
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0016 0.0082 0.0052
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.1258 0.4523
Schistosoma mansoni hypothetical protein 0.0139 0.1743 0.1724
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0348 0.0348
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0186 0.0607
Trypanosoma brucei unspecified product 0.0016 0.0089 0.0245
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0286 0.0341
Schistosoma mansoni ran 0.0044 0.0459 0.0437
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0045 0.0482 0.1473
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.075 0.0729
Echinococcus granulosus lamin 0.0026 0.0229 0.0229
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.02 0.02
Echinococcus multilocularis leucyl aminopeptidase 0.0023 0.0181 0.0181
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0071 0.0024
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0044 0.0459 0.0459
Echinococcus granulosus importin 5 0.0011 0.0023 0.0023
Plasmodium vivax importin-beta 2, putative 0.0059 0.0669 0.4626
Plasmodium falciparum thioredoxin reductase 0.0014 0.0061 0.0273
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0089 0.0245
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0153 0.0485
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0021 0.0153 0.0225
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0348 0.07
Onchocerca volvulus Serine\/threonine kinase homolog 0.0103 0.1258 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0061 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0558 0.1292
Echinococcus granulosus GPCR family 2 0.0064 0.0738 0.0738
Loa Loa (eye worm) hypothetical protein 0.0059 0.0669 0.0798
Loa Loa (eye worm) bromodomain containing protein 0.0016 0.0082 0.0097
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0203 0.2609 0.3112
Plasmodium falciparum acyl-CoA synthetase 0.0016 0.0082 0.0425
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0014 0.0061 0.0157
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0186 0.0499
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0061 0.0142
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0071 0.0024
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.1146 0.1146
Echinococcus granulosus lamin dm0 0.0026 0.0229 0.0229
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0186 0.0164
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0061 0.0028
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0348 0.0348
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0153 0.0225
Schistosoma mansoni leucine aminopeptidase 0.0023 0.0181 0.0158
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0089 0.0245
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0115 0.1421 0.5133
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0417 0.1367
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0044 0.0459 0.14
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0348 0.0786
Schistosoma mansoni zinc finger protein 0.0019 0.0128 0.0105
Echinococcus granulosus dnaJ subfamily B 0.0437 0.5771 0.5771
Schistosoma mansoni apoferritin-2 0.0017 0.0106 0.0084
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0014 0.0061 0.0273
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0186 0.0305
Echinococcus granulosus methyl CpG binding domain protein 2 0.0015 0.0074 0.0074
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0014 0.0061 0.0273
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0153 0.0116
Mycobacterium ulcerans leucyl aminopeptidase 0.0115 0.1421 0.3312
Trypanosoma brucei unspecified product 0.0016 0.0089 0.0245
Brugia malayi cytosol aminopeptidase 0.0023 0.0181 0.053
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0044 0.0459 0.1619
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0017 0.0106 0.0334
Mycobacterium ulcerans hypothetical protein 0.0024 0.02 0.0338
Plasmodium vivax acyl-CoA synthetase, putative 0.0016 0.0082 0.0425
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0519 0.1746
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0348 0.1107
Loa Loa (eye worm) glutathione reductase 0.004 0.0417 0.0498
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0186 0.0395
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0106 0.0111
Schistosoma mansoni hypothetical protein 0.0018 0.0117 0.0094
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0519 0.1197
Mycobacterium leprae Probable lipase LipE 0.0035 0.0348 0.0596
Echinococcus multilocularis expressed protein 0.0017 0.0106 0.0106
Echinococcus multilocularis lamin 0.0026 0.0229 0.0229
Leishmania major DNA polymerase eta, putative 0.0023 0.0186 0.0607
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0186 0.0499
Loa Loa (eye worm) TAR-binding protein 0.0193 0.2471 0.2947
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0348 0.07
Schistosoma mansoni intermediate filament proteins 0.0026 0.0229 0.0207
Schistosoma mansoni cpg binding protein 0.0031 0.0286 0.0264
Schistosoma mansoni methyl-cpg binding protein mbd 0.0015 0.0074 0.0052
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0153 0.0485
Echinococcus granulosus histone lysine methyltransferase setb 0.0016 0.0083 0.0083
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0153 0.0225
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0348 0.1055
Echinococcus granulosus dna polymerase kappa 0.0023 0.0186 0.0186
Schistosoma mansoni lamin 0.0026 0.0229 0.0207
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0044 0.0459 0.3323
Schistosoma mansoni tar DNA-binding protein 0.0193 0.2471 0.2454
Echinococcus granulosus expressed protein 0.0017 0.0106 0.0106
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0045 0.0482 0.0461
Schistosoma mansoni hypothetical protein 0.0013 0.0053 0.0031
Leishmania major trypanothione reductase 0.004 0.0417 0.1465
Loa Loa (eye worm) hypothetical protein 0.0035 0.0348 0.0415
Schistosoma mansoni kinase 0.0052 0.0576 0.0555
Trichomonas vaginalis ferritin, putative 0.0017 0.0106 0.0202
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0186 0.0607
Loa Loa (eye worm) hypothetical protein 0.0062 0.0711 0.0848
Entamoeba histolytica hypothetical protein 0.0048 0.0519 0.4013
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.0669 0.4626
Echinococcus multilocularis musashi 0.0026 0.0229 0.0229
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1258 0.2982
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0044 0.0459 0.0547
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.1258 0.4523
Echinococcus granulosus tar DNA binding protein 0.0193 0.2471 0.2471
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0558 0.1292
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0115 0.1421 1
Loa Loa (eye worm) PHD-finger family protein 0.0018 0.0117 0.0139
Echinococcus granulosus cpg binding protein 0.0034 0.0332 0.0332
Loa Loa (eye worm) beta-lactamase 0.0035 0.0348 0.0415
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1146 0.1126
Brugia malayi RNA binding protein 0.0193 0.2471 0.7685
Brugia malayi PHD-finger family protein 0.0024 0.0191 0.0563
Echinococcus granulosus ornithine aminotransferase 0.0045 0.0482 0.0482
Loa Loa (eye worm) hypothetical protein 0.0036 0.0355 0.0424
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0045 0.0482 0.1027
Echinococcus multilocularis dnaJ subfamily B 0.0437 0.5771 0.5771
Echinococcus granulosus dna polymerase eta 0.0023 0.0186 0.0186
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1258 0.2982
Schistosoma mansoni lamin 0.0026 0.0229 0.0207
Loa Loa (eye worm) hypothetical protein 0.0016 0.0082 0.0098
Loa Loa (eye worm) hypothetical protein 0.0021 0.0153 0.0183
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0186 0.0222
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0015 0.0074 0.0074
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0014 0.0061 0.0273
Echinococcus granulosus leucine aminopeptidase protein 0.0115 0.1421 0.1421
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0032 0.0298 0.0298
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0106 0.0111
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0044 0.0459 0.312
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0023 0.0181 0.0586
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0045 0.0482 0.1027
Brugia malayi Bromodomain containing protein 0.0068 0.0786 0.242
Mycobacterium ulcerans L-lysine aminotransferase 0.0045 0.0482 0.1027
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0045 0.0482 0.31
Plasmodium falciparum glutathione reductase 0.004 0.0417 0.2824
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.1258 0.1238
Schistosoma mansoni ferritin light chain 0.0017 0.0106 0.0084
Entamoeba histolytica acyl-coA synthetase, putative 0.0021 0.0153 0.1057
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0023 0.0181 0.0477
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0348 0.07
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.1146 0.1146
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0669 0.24
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0348 0.07
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0023 0.0181 0.0181
Loa Loa (eye worm) thioredoxin reductase 0.004 0.0417 0.0498
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0631 0.8386 1
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0045 0.0482 0.1027
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0229 0.0273
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0023 0.0181 0.0158
Loa Loa (eye worm) hypothetical protein 0.0035 0.0348 0.0415
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0229 0.0273
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0045 0.0482 0.0926
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1258 0.2982
Echinococcus granulosus geminin 0.0349 0.4584 0.4584
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0103 0.1258 0.15
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0153 0.0225
Plasmodium falciparum thioredoxin reductase 0.004 0.0417 0.2824
Brugia malayi Bromodomain containing protein 0.0034 0.0326 0.0986
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0348 0.07
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0186 0.0305
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.02 0.0656
Schistosoma mansoni bromodomain containing protein 0.0057 0.0647 0.0625
Trichomonas vaginalis ran, putative 0.0044 0.0459 0.1052
Schistosoma mansoni hypothetical protein 0.0437 0.5771 0.5762
Schistosoma mansoni cpg binding protein 0.0034 0.0332 0.031
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0186 0.0607
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0045 0.0482 0.1027
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0669 0.24
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0153 0.0225
Loa Loa (eye worm) kap beta 3 protein 0.0011 0.0023 0.0027
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0106 0.0111
Schistosoma mansoni hypothetical protein 0.0349 0.4584 0.4572
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.1146 0.1367
Mycobacterium tuberculosis Probable dehydrogenase 0.0092 0.1116 0.2571
Toxoplasma gondii NADPH-glutathione reductase 0.0014 0.0061 0.0273
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0103 0.1255 0.2909
Schistosoma mansoni hypothetical protein 0.0349 0.4584 0.4572
Echinococcus multilocularis transportin 1 0.0011 0.0023 0.0023
Mycobacterium tuberculosis Probable reductase 0.0092 0.1116 0.2571
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0153 0.0485
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.02 0.02
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.1146 0.1146
Echinococcus multilocularis leucyl aminopeptidase 0.0023 0.0181 0.0181
Schistosoma mansoni tar DNA-binding protein 0.0193 0.2471 0.2454
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1258 0.2982
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0023 0.0181 0.0586
Echinococcus granulosus intermediate filament protein 0.0026 0.0229 0.0229
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0163 0.0163
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0348 0.0415
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0348 0.0786
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0023 0.0181 0.0477
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0063 0.0075
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0021 0.0032
Brugia malayi beta-lactamase family protein 0.0035 0.0348 0.1055
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0016 0.0082 0.0156
Schistosoma mansoni zinc finger protein 0.0013 0.0053 0.0031
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0348 0.0786
Schistosoma mansoni microtubule-associated protein tau 0.0751 1 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0044 0.0053
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0023 0.0181 0.0586
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0045 0.0482 0.3288
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0063 0.0163
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0186 0.0607
Brugia malayi glutathione reductase 0.004 0.0417 0.127
Loa Loa (eye worm) hypothetical protein 0.0021 0.0153 0.0183
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0153 0.0225
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0318 0.4167 1
Plasmodium falciparum ornithine aminotransferase 0.0045 0.0482 0.3288
Schistosoma mansoni ferritin 0.0017 0.0106 0.0084
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0103 0.1255 0.2909
Trichomonas vaginalis esterase, putative 0.0035 0.0348 0.0786
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0061 0.0028
Mycobacterium tuberculosis Conserved protein 0.0035 0.0348 0.07
Schistosoma mansoni hypothetical protein 0.0064 0.0738 0.0717
Schistosoma mansoni hypothetical protein 0.0631 0.8386 0.8382
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0023 0.0181 0.0215
Trypanosoma brucei trypanothione reductase 0.004 0.0417 0.1465
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0318 0.4167 1
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0115 0.1421 0.3312
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0186 0.0164
Brugia malayi RNA, U transporter 1 0.0168 0.214 0.665
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1258 0.2982
Giardia lamblia Kinase, PLK 0.0103 0.1258 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0064 0.0738 0.088
Chlamydia trachomatis cytosol aminopeptidase 0.0115 0.1421 1
Mycobacterium tuberculosis Conserved protein 0.0035 0.0348 0.07
Brugia malayi Calcitonin receptor-like protein seb-1 0.0203 0.2609 0.8116
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0014 0.0061 0.0142
Schistosoma mansoni methyl-cpg binding protein mbd 0.0015 0.0074 0.0052
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0106 0.0111
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0186 0.0607
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0163 0.0163
Trypanosoma brucei polo-like protein kinase 0.0103 0.1258 0.4586
Echinococcus multilocularis geminin 0.0349 0.4584 0.4584
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0186 0.0305
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0153 0.0116
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0044 0.0044
Plasmodium falciparum M17 leucyl aminopeptidase 0.0115 0.1421 1
Trichomonas vaginalis glutathione reductase, putative 0.0014 0.0061 0.0092
Plasmodium falciparum glutathione reductase 0.0014 0.0061 0.0273
Loa Loa (eye worm) hypothetical protein 0.0016 0.0082 0.0098
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0023 0.0181 0.0586
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0061 0.0028
Echinococcus multilocularis cpg binding protein 0.0034 0.0332 0.0332
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0153 0.0445
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0348 0.1107
Schistosoma mansoni hypothetical protein 0.0064 0.0738 0.0717
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0016 0.0083 0.0061
Trypanosoma brucei unspecified product 0.0023 0.0186 0.0607
Brugia malayi intermediate filament protein 0.0026 0.0229 0.0681
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0021 0.0153 0.0225
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0685 0.4735
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0064 0.0738 0.0738
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0054 0.0604 0.0604
Echinococcus multilocularis ornithine aminotransferase 0.0045 0.0482 0.0482
Trypanosoma brucei hypothetical protein, conserved 0.0211 0.2717 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0348 0.0415
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0103 0.1258 0.1258
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.1146 0.1146
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0186 0.0607
Echinococcus multilocularis ornithine aminotransferase 0.0045 0.0482 0.0482
Loa Loa (eye worm) hypothetical protein 0.0035 0.0348 0.0415
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0071 0.0024
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0023 0.0181 0.053
Leishmania major importin beta-1 subunit, putative 0.0048 0.0519 0.184
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0071 0.0024
Leishmania major hypothetical protein, conserved 0.0013 0.0053 0.0114
Entamoeba histolytica serine/threonine protein kinase, putative 0.0103 0.1258 1
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.02 0.0338
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.02 0.0548
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0092 0.1116 0.2571
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0186 0.0548
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0193 0.2471 0.2947
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0016 0.0082 0.0052
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0061 0.0028
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0713 0.9496 0.9496
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0348 0.07
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0348 0.0786
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0348 0.07
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0023 0.0181 0.0215
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0014 0.0061 0.0061
Echinococcus multilocularis ferritin 0.0017 0.0106 0.0106
Schistosoma mansoni ferritin 0.0017 0.0106 0.0084
Onchocerca volvulus 0.0035 0.0348 0.1766
Mycobacterium tuberculosis Conserved protein 0.0035 0.0348 0.07
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0021 0.0153 0.0225
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.02 0.0338
Trypanosoma brucei ISWI complex protein 0.0013 0.0053 0.0114
Echinococcus multilocularis microtubule associated protein 2 0.0751 1 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0229 0.0273
Loa Loa (eye worm) hypothetical protein 0.0016 0.0083 0.0099
Echinococcus multilocularis GPCR, family 2 0.0064 0.0738 0.0738
Echinococcus multilocularis Aminotransferase class III 0.0045 0.0482 0.0482
Schistosoma mansoni apoferritin-2 0.0017 0.0106 0.0084
Leishmania major hypothetical protein, conserved 0.0035 0.0348 0.1209
Loa Loa (eye worm) hypothetical protein 0.0203 0.2609 0.3112
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0348 0.07
Loa Loa (eye worm) hypothetical protein 0.0016 0.0082 0.0098
Mycobacterium tuberculosis Probable aminotransferase 0.0318 0.4167 1
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0023 0.0181 0.0586
Leishmania major GTP-binding protein, putative 0.0044 0.0459 0.1619
Echinococcus granulosus GTP binding nuclear protein Ran 0.0044 0.0459 0.0459
Schistosoma mansoni importin beta-1 0.0059 0.0669 0.0648
Mycobacterium ulcerans hypothetical protein 0.0035 0.0348 0.07
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0061 0.0028
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0186 0.0499
Loa Loa (eye worm) hypothetical protein 0.0035 0.0348 0.0415
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.2916 0.6955
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0318 0.4167 1
Echinococcus granulosus translational activator gcn1 0.0011 0.0023 0.0023
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0115 0.1421 0.5133
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0014 0.0061 0.0273
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0045 0.0482 0.31
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.02 0.0427
Schistosoma mansoni tar DNA-binding protein 0.0193 0.2471 0.2454
Loa Loa (eye worm) hypothetical protein 0.0021 0.0153 0.0183
Brugia malayi latrophilin 2 splice variant baaae 0.0139 0.1743 0.5411
Echinococcus granulosus zinc finger protein 0.0019 0.0128 0.0128
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0248 0.3212 0.3831
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0014 0.0061 0.0061
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0186 0.0499
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0016 0.0083 0.0083
Brugia malayi serine/threonine-protein kinase plk-2 0.0103 0.1258 0.3896
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0186 0.0186
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0186 0.0395
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0061 0.0142
Mycobacterium ulcerans hypothetical protein 0.0318 0.4167 1
Toxoplasma gondii leucyl aminopeptidase LAP 0.0115 0.1421 1
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.2717 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0045
Echinococcus multilocularis thioredoxin glutathione reductase 0.0041 0.0425 0.0425
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0089 0.0245
Echinococcus granulosus leucyl aminopeptidase 0.0023 0.0181 0.0181
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0348 0.07
Echinococcus granulosus thioredoxin glutathione reductase 0.0041 0.0425 0.0425
Onchocerca volvulus 0.0031 0.0286 0.1202
Loa Loa (eye worm) hypothetical protein 0.0064 0.0738 0.088
Echinococcus multilocularis importin 5 0.0011 0.0023 0.0023
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0186 0.0186
Brugia malayi Latrophilin receptor protein 2 0.0064 0.0738 0.2272
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.02 0.0338
Mycobacterium tuberculosis Probable oxidoreductase 0.0103 0.1255 0.2909
Onchocerca volvulus 0.0035 0.0348 0.1766
Trypanosoma brucei aminopeptidase, putative 0.0023 0.0181 0.0586
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0186 0.0499
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0163 0.0141
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.02 0.0338
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0153 0.0225
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0186 0.0548
Onchocerca volvulus 0.0035 0.0348 0.1766
Schistosoma mansoni ran 0.0044 0.0459 0.0437
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0045 0.0482 0.1027
Echinococcus multilocularis lamin dm0 0.0026 0.0229 0.0229
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0103 0.1258 0.4586
Schistosoma mansoni hypothetical protein 0.0064 0.0738 0.0717
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0061 0.0028
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0348 0.1209
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0186 0.0607
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1258 0.2982

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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