Detailed information for compound 1782092

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 307.732 | Formula: C14H14ClN3O3
  • H donors: 1 H acceptors: 4 LogP: 2.79 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)/C=C/c1ncc(n1CC(O)C)[N+](=O)[O-]
  • InChi: 1S/C14H14ClN3O3/c1-10(19)9-17-13(16-8-14(17)18(20)21)7-4-11-2-5-12(15)6-3-11/h2-8,10,19H,9H2,1H3/b7-4+
  • InChiKey: XPRNKSCDBLSGRL-QPJJXVBHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0011 0.0019 0.0013
Echinococcus multilocularis calpain 7 (C02 family) 0.0146 0.058 0.0574
Giardia lamblia Cathepsin B precursor 0.0904 0.3737 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0414 0.1696 0.1691
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0015 0.0008
Echinococcus granulosus neuropeptide receptor 0.0011 0.0019 0.0013
Giardia lamblia Cathepsin L precursor 0.023 0.0932 0.2309
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0099 0.0093
Plasmodium falciparum serine repeat antigen 4 0.023 0.0932 0.2199
Echinococcus granulosus cathepsin L 0.023 0.0932 0.0926
Entamoeba histolytica calpain family cysteine protease, putative 0.0044 0.0156 0.0179
Schistosoma mansoni calpain-7 (C02 family) 0.0146 0.058 0.0574
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0015 0.0008
Echinococcus granulosus peptide allatostatin:somatostatin 0.0011 0.0019 0.0013
Loa Loa (eye worm) papain family cysteine protease containing protein 0.023 0.0932 0.0926
Toxoplasma gondii cathepsin B 0.0904 0.3737 0.9499
Schistosoma mansoni amine GPCR 0.0011 0.0019 0.0013
Giardia lamblia Cathepsin L-like protease 0.023 0.0932 0.2309
Schistosoma mansoni hypothetical protein 0.0398 0.1632 0.1626
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.023 0.0932 0.2373
Schistosoma mansoni thyroid hormone receptor 0.001 0.0015 0.0008
Toxoplasma gondii hypothetical protein 0.0044 0.0156 0.0179
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0015 0.0008
Schistosoma mansoni cpg binding protein 0.0028 0.009 0.0083
Loa Loa (eye worm) fibroinase 0.095 0.3929 0.3925
Echinococcus granulosus g protein coupled receptor 0.0011 0.0019 0.0013
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0015 0.0008
Entamoeba histolytica cysteine proteinase 1, putative 0.0522 0.2147 0.5362
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.023 0.0932 0.2199
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0099 0.0093
Onchocerca volvulus 0.0011 0.0019 0.0012
Loa Loa (eye worm) papain family cysteine protease containing protein 0.095 0.3929 0.3925
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Schistosoma mansoni neuropeptide receptor 0.0011 0.0019 0.0013
Echinococcus granulosus 7tm_1 domain containing protein 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0087 0.0081
Giardia lamblia Cysteine protease 0.023 0.0932 0.2309
Schistosoma mansoni nuclear hormone receptor 0.001 0.0015 0.0008
Echinococcus granulosus calpain 5 0.0146 0.058 0.0574
Giardia lamblia Cysteine protease 0.023 0.0932 0.2309
Loa Loa (eye worm) hypothetical protein 0.023 0.0932 0.0926
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0904 0.3737 0.9499
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0015 0.0008
Onchocerca volvulus 0.0011 0.0019 0.0012
Brugia malayi calpain 5 0.0044 0.0156 0.015
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0011 0.0019 0.0013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Entamoeba histolytica cysteine proteinase, putative 0.0522 0.2147 0.5362
Echinococcus multilocularis calumenin 0.0028 0.009 0.0084
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.023 0.0931 0.0925
Brugia malayi cathepsin L precursor 0.023 0.0932 0.0926
Brugia malayi Papain family cysteine protease containing protein 0.0522 0.2147 0.2142
Echinococcus granulosus FTZ F1 alpha 0.001 0.0015 0.0008
Schistosoma mansoni hypothetical protein 0.0027 0.0087 0.0081
Onchocerca volvulus 0.0028 0.009 0.0193
Brugia malayi hypothetical protein 0.0011 0.0019 0.0013
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0177 0.0171
Echinococcus granulosus cathepsin b 0.2409 1 1
Brugia malayi calcium-binding protein 0.0027 0.0087 0.0081
Echinococcus multilocularis GPCR, family 2 0.0015 0.0038 0.0031
Brugia malayi hypothetical protein 0.0011 0.0019 0.0013
Onchocerca volvulus 0.0011 0.0019 0.0012
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0522 0.2147 0.2142
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.023 0.0932 0.2373
Echinococcus multilocularis geminin 0.0331 0.1353 0.1347
Echinococcus multilocularis g protein coupled receptor 0.0011 0.0019 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.023 0.0932 0.2373
Echinococcus granulosus dnaJ subfamily B 0.0398 0.1632 0.1626
Entamoeba histolytica cysteine protease, putative 0.023 0.0932 0.2199
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0146 0.058 0.1283
Echinococcus multilocularis calmodulin 0.0027 0.0087 0.0081
Loa Loa (eye worm) G-protein coupled receptor 0.0011 0.0019 0.0013
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0011 0.0019 0.0013
Brugia malayi Papain family cysteine protease containing protein 0.095 0.3929 0.3925
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.0545 0.0538
Echinococcus granulosus cathepsin L cysteine protease 0.0522 0.2147 0.2142
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.0835 0.0829
Loa Loa (eye worm) hypothetical protein 0.0022 0.0064 0.0057
Loa Loa (eye worm) hypothetical protein 0.0658 0.2714 0.2709
Plasmodium falciparum serine repeat antigen 2 0.023 0.0932 0.2199
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0011 0.0019 0.0013
Schistosoma mansoni ef hand domain family member A2 0.0027 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2409 1 1
Entamoeba histolytica cysteine protease, putative 0.023 0.0932 0.2199
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0019 0.0013
Entamoeba histolytica cysteine proteinase, putative 0.0522 0.2147 0.5362
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Trichomonas vaginalis centrin, putative 0.0027 0.0087 0.0223
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.023 0.0932 0.2373
Onchocerca volvulus 0.0027 0.0087 0.0185
Trichomonas vaginalis calmodulin, putative 0.0028 0.009 0.023
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0159 0.0153
Onchocerca volvulus 0.0011 0.0019 0.0012
Echinococcus multilocularis cathepsin l cysteine peptidase 0.095 0.3929 0.3925
Brugia malayi Matrixin family protein 0.0022 0.0064 0.0057
Entamoeba histolytica cysteine protease, putative 0.0522 0.2147 0.5362
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.023 0.0932 0.2199
Loa Loa (eye worm) hypothetical protein 0.0022 0.0064 0.0057
Schistosoma mansoni reticulocalbin 0.0027 0.0087 0.0081
Loa Loa (eye worm) calpain 5 0.0102 0.0398 0.0392
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.095 0.3929 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.023 0.0932 0.0926
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0146 0.058 0.1283
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2409 1 1
Schistosoma mansoni neuronal calcium sensor 0.0027 0.0087 0.0081
Schistosoma mansoni calmodulin 0.0027 0.0087 0.0081
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0011 0.0019 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.095 0.3929 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0146 0.0373
Giardia lamblia Cathepsin L precursor 0.023 0.0932 0.2309
Echinococcus multilocularis calpain 0.0146 0.058 0.0574
Giardia lamblia Cathepsin B precursor 0.023 0.0932 0.2309
Plasmodium vivax vivapain-2 0.095 0.3929 1
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.0561 0.0555
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0011 0.0019 0.0013
Loa Loa (eye worm) neuropeptide F receptor 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0015 0.0008
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.023 0.0931 0.0925
Echinococcus multilocularis sex peptide receptor 0.0011 0.0019 0.0013
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0079 0.0301 0.0294
Onchocerca volvulus 0.0011 0.0019 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.095 0.3929 1
Onchocerca volvulus Cathepsin L homolog 0.095 0.3929 1
Echinococcus granulosus cathepsin l1 0.095 0.3929 0.3925
Echinococcus granulosus calmodulin 0.0027 0.0087 0.0081
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0011 0.0019 0.0013
Leishmania major cathepsin L-like protease 0.095 0.3929 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.095 0.3929 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Schistosoma mansoni hypothetical protein 0.0011 0.0019 0.0013
Schistosoma mansoni cathepsin s 0.0292 0.1189 0.1183
Giardia lamblia Cathepsin L precursor 0.023 0.0932 0.2309
Brugia malayi Cathepsin L-like precursor 0.095 0.3929 0.3925
Schistosoma mansoni opsin-like receptor 0.0011 0.0019 0.0013
Schistosoma mansoni cathepsin F (C01 family) 0.095 0.3929 0.3925
Onchocerca volvulus 0.0031 0.0101 0.022
Plasmodium falciparum serine repeat antigen 9 0.023 0.0932 0.2199
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0146 0.058 0.0497
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.023 0.0932 0.0926
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0008
Giardia lamblia Dipeptidyl-peptidase I precursor 0.023 0.0932 0.2309
Giardia lamblia Dipeptidyl-peptidase I precursor 0.023 0.0932 0.2309
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0146 0.058 0.0497
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0028 0.009 0.0003
Schistosoma mansoni biogenic amine receptor 0.0011 0.0019 0.0013
Plasmodium vivax hypothetical protein, conserved 0.0028 0.009 0.0008
Echinococcus multilocularis centrin 2 0.0027 0.0087 0.0081
Brugia malayi Cathepsin L-like precursor 0.0658 0.2714 0.2709
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0011 0.0019 0.0013
Entamoeba histolytica calpain large subunit domain III containing protein 0.0102 0.0398 0.0808
Echinococcus granulosus tm gpcr rhodopsin 0.0011 0.0019 0.0013
Brugia malayi larval opioid receptor 0.0011 0.0019 0.0013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Echinococcus multilocularis neuronal calcium sensor 0.0027 0.0087 0.0081
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0008
Schistosoma mansoni cpg binding protein 0.003 0.0097 0.009
Giardia lamblia Cathepsin B precursor 0.0904 0.3737 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0069
Loa Loa (eye worm) ctsf protein 0.095 0.3929 0.3925
Brugia malayi Cathepsin L-like precursor 0.095 0.3929 0.3925
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0522 0.2147 0.2142
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Schistosoma mansoni cathepsin F (C01 family) 0.0658 0.2714 0.2709
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0159 0.0153
Onchocerca volvulus 0.0011 0.0019 0.0012
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.023 0.0932 0.0926
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Brugia malayi calpain 7 0.0146 0.058 0.0574
Schistosoma mansoni cathepsin C 0.023 0.0932 0.0926
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0015 0.0008
Echinococcus multilocularis EF hand domain containing family member A2 0.0027 0.0087 0.0081
Giardia lamblia Cathepsin L precursor 0.023 0.0932 0.2309
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0011 0.0019 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.023 0.0932 0.2373
Plasmodium vivax serine-repeat antigen (SERA), putative 0.023 0.0932 0.2199
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0015 0.0008
Plasmodium vivax vivapain-1 0.0522 0.2147 0.5362
Echinococcus granulosus cathepsin L cysteine proteinase 0.095 0.3929 0.3925
Brugia malayi hypothetical protein 0.0011 0.0019 0.0013
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.023 0.0932 0.2199
Echinococcus multilocularis neuropeptide s receptor 0.0011 0.0019 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0522 0.2147 0.5362
Brugia malayi putative neuropeptide receptor 0.0011 0.0019 0.0013
Echinococcus multilocularis serotonin receptor 0.0152 0.0605 0.0599
Echinococcus multilocularis cathepsin L 0.0522 0.2147 0.2142
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.023 0.0932 0.0926
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0062 0.0232 0.0225
Trypanosoma brucei Calpain-like protein 1.2 0.0044 0.0156 0.0179
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Trypanosoma brucei calpain, putative 0.0044 0.0156 0.0179
Onchocerca volvulus 0.0011 0.0019 0.0012
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0414 0.1696 0.1691
Echinococcus multilocularis calbindin 32 0.0028 0.009 0.0084
Entamoeba histolytica hypothetical protein 0.023 0.0932 0.2199
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0038 0.0031
Trichomonas vaginalis calcium binding protein, putative 0.0027 0.0087 0.0223
Plasmodium falciparum serine repeat antigen 6 0.023 0.0932 0.2199
Echinococcus granulosus biogenic amine 5HT receptor 0.0152 0.0605 0.0599
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2409 1 1
Schistosoma mansoni hypothetical protein 0.0031 0.0101 0.0095
Loa Loa (eye worm) hypothetical protein 0.2409 1 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0011 0.0019 0.0013
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.023 0.0932 0.2199
Echinococcus granulosus programmed cell death protein 0.0027 0.0087 0.0081
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0015 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.023 0.0932 0.2373
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0015 0.0008
Echinococcus granulosus sex peptide receptor 0.0011 0.0019 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0015 0.0008
Schistosoma mansoni amine GPCR 0.0011 0.0019 0.0013
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0146 0.058 0.0497
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0015 0.0008
Echinococcus multilocularis cysteine protease 0.095 0.3929 0.3925
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0113 0.0106
Brugia malayi Cathepsin L-like cysteine proteinase 0.0658 0.2714 0.2709
Brugia malayi hypothetical protein 0.0011 0.0019 0.0013
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Echinococcus multilocularis programmed cell death protein 0.0027 0.0087 0.0081
Brugia malayi ORL1-like opioid receptor 0.0011 0.0019 0.0013
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0038 0.0031
Brugia malayi Cathepsin L-like precursor 0.095 0.3929 0.3925
Trichomonas vaginalis calcineurin B subunit, putative 0.0027 0.0087 0.0223
Trypanosoma cruzi cysteine proteinase, putative 0.0522 0.2147 0.2078
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.023 0.0932 0.2373
Echinococcus granulosus hypothetical protein 0.0011 0.0019 0.0013
Leishmania major calpain family cysteine protease-like protein 0.0044 0.0156 0.0179
Echinococcus multilocularis neuropeptide Y receptor 0.0011 0.0019 0.0013
Schistosoma mansoni calpain-2 (C02 family) 0.0044 0.0156 0.015
Entamoeba histolytica papain family cysteine protease domain containing protein 0.023 0.0932 0.2199
Echinococcus granulosus cysteine protease 0.0522 0.2147 0.2142
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Plasmodium vivax unspecified product 0.0522 0.2147 0.5362
Onchocerca volvulus 0.0011 0.0019 0.0012
Schistosoma mansoni reticulocalbin 0.0028 0.009 0.0084
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0015 0.0008
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0011 0.0019 0.0013
Entamoeba histolytica cysteine protease, putative 0.0522 0.2147 0.5362
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.023 0.0932 0.2199
Entamoeba histolytica cysteine proteinase, putative 0.0522 0.2147 0.5362
Echinococcus granulosus calpain A 0.0415 0.1699 0.1694
Giardia lamblia Cathepsin B precursor 0.023 0.0932 0.2309
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0292 0.1189 0.1183
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0044 0.0156 0.0397
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0015 0.0008
Brugia malayi calpain family protein 1 0.0386 0.1582 0.1577
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0092 0.0086
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0177 0.0171
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0146 0.058 0.1283
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0011 0.0019 0.0013
Brugia malayi calpain D 0.0044 0.0156 0.015
Loa Loa (eye worm) acetyltransferase 0.0141 0.0561 0.0555
Entamoeba histolytica grainin, putative 0.0028 0.009 0.0008
Trypanosoma cruzi cysteine proteinase, putative 0.0522 0.2147 0.2078
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Brugia malayi MH2 domain containing protein 0.0116 0.0458 0.0452
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.095 0.3929 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0087 0.0081
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0011 0.0019 0.0013
Echinococcus granulosus g-protein coupled receptor 0.0011 0.0019 0.0013
Brugia malayi RE15519p 0.0011 0.0019 0.0013
Echinococcus granulosus calpain 7 C02 family 0.0146 0.058 0.0574
Schistosoma mansoni biogenic amine (5HT) receptor 0.0152 0.0605 0.0599
Toxoplasma gondii calmodulin CAM1 0.0028 0.009 0.0008
Schistosoma mansoni centrin 0.0027 0.0087 0.0081
Loa Loa (eye worm) calpain 0.0146 0.058 0.0574
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0159 0.0153
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0015 0.0008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0904 0.3737 0.3733
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.095 0.3929 1
Loa Loa (eye worm) neuropeptide F receptor 0.0011 0.0019 0.0013
Trichomonas vaginalis myosin light chain 1, putative 0.0027 0.0087 0.0223
Schistosoma mansoni histamine h1 receptor 0.0011 0.0019 0.0013
Echinococcus granulosus neurocalcin 0.0027 0.0087 0.0081
Echinococcus granulosus cathepsin l1 0.0658 0.2714 0.2709
Plasmodium falciparum serine repeat antigen 8 0.023 0.0932 0.2199
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.023 0.0932 0.0926
Leishmania major cysteine peptidase A (CPA) 0.095 0.3929 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1586 0.6577 0.6575
Brugia malayi nuclear receptor NHR-88 0.001 0.0015 0.0008
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.023 0.0932 0.0926
Toxoplasma gondii cathepsin CPC1 0.023 0.0932 0.2199
Leishmania major cathepsin L-like protease 0.095 0.3929 1
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0146 0.058 0.0497
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0019 0.0013
Echinococcus granulosus g protein coupled receptor 0.0011 0.0019 0.0013
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0015 0.0008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0159 0.0153
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0146 0.058 0.0497
Schistosoma mansoni neuronal calcium sensor 0.0027 0.0087 0.0081
Brugia malayi G protein-coupled receptor 0.0011 0.0019 0.0013
Leishmania major hypothetical protein, conserved 0.0028 0.009 0.0008
Trichomonas vaginalis calmodulin, putative 0.0027 0.0087 0.0223
Brugia malayi neuropeptide F receptor 0.0011 0.0019 0.0013
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0146 0.058 0.0497
Brugia malayi Pre-SET motif family protein 0.0207 0.0835 0.0829
Schistosoma mansoni alpha-1 adrenergic receptor 0.0011 0.0019 0.0013
Plasmodium vivax vivapain-3 0.0522 0.2147 0.5362
Loa Loa (eye worm) matrix metalloproteinase 0.0022 0.0064 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0156 0.0397
Brugia malayi GnHR receptor homolog 0.0011 0.0019 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0019 0.0013
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0069
Trypanosoma cruzi cysteine peptidase, putative 0.095 0.3929 0.3876
Echinococcus granulosus EF HAND 1 calcium binding site 0.0027 0.0087 0.0081
Schistosoma mansoni mitochondrial solute carrier 0.0027 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.0033 0.0113 0.0106
Loa Loa (eye worm) hypothetical protein 0.003 0.0099 0.0093
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0015 0.0008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0011 0.0019 0.0013
Echinococcus multilocularis neuropeptides capa receptor 0.0011 0.0019 0.0013
Brugia malayi cathepsin Z-like cysteine proteinase 0.023 0.0932 0.0926
Giardia lamblia Cathepsin B precursor 0.023 0.0932 0.2309
Giardia lamblia Cathepsin L precursor 0.023 0.0932 0.2309
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Onchocerca volvulus Neuropeptide F receptor homolog 0.0011 0.0019 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0015 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0146 0.058 0.1283
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.023 0.0932 0.2309
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0011 0.0019 0.0013
Echinococcus multilocularis G protein coupled receptor 139 0.0011 0.0019 0.0013
Schistosoma mansoni neuropeptide receptor 0.0011 0.0019 0.0013
Echinococcus multilocularis calpain family protein 1, d 0.0285 0.1158 0.1152
Onchocerca volvulus Matrilysin homolog 0.0048 0.0173 0.0404
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0011 0.0019 0.0013
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0011 0.0019 0.0013
Schistosoma mansoni opsin-like receptor 0.0011 0.0019 0.0013
Brugia malayi EF hand family protein 0.0027 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0011 0.0019 0.0013
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0014 0.0008
Brugia malayi Matrixin family protein 0.0022 0.0064 0.0057
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Brugia malayi hypothetical protein 0.0011 0.0019 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0015 0.0008
Giardia lamblia Cathepsin B precursor 0.0904 0.3737 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0069
Loa Loa (eye worm) matrixin family protein 0.0052 0.0191 0.0185
Plasmodium falciparum serine repeat antigen 5 0.023 0.0932 0.2199
Schistosoma mansoni biogenic amine (5HT) receptor 0.0011 0.0019 0.0013
Brugia malayi cathepsin F-like cysteine proteinase 0.023 0.0932 0.0926
Toxoplasma gondii cathepsin CPL 0.095 0.3929 1
Schistosoma mansoni hypothetical protein 0.0015 0.0038 0.0031
Giardia lamblia Encystation-specific protease 0.023 0.0932 0.2309
Loa Loa (eye worm) histone methyltransferase 0.001 0.0014 0.0008
Schistosoma mansoni Mername-AA248 (C02 family) 0.0146 0.058 0.0574
Echinococcus multilocularis cathepsin L cysteine protease 0.095 0.3929 0.3925
Loa Loa (eye worm) calmodulin-like protein 0.0027 0.0087 0.0081
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0069
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0019 0.0013
Brugia malayi Matrixin family protein 0.0022 0.0064 0.0057
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0146 0.058 0.0497
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.023 0.0932 0.2373
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0069
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0044 0.0156 0.0069
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0044 0.0156 0.0179
Loa Loa (eye worm) melatonin receptor type 1A 0.0011 0.0019 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0019 0.0013
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0069
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0044 0.0156 0.0069
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0044 0.0158 0.0184
Echinococcus granulosus EF hand domain containing family member A2 0.0027 0.0087 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.023 0.0932 0.2373
Trichomonas vaginalis calmodulin, putative 0.0027 0.0087 0.0223
Echinococcus granulosus calpain A 0.0146 0.058 0.0574
Brugia malayi programmed cell death protein 6 0.0027 0.0087 0.0081
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.006 0.0224 0.0218
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0015 0.0008
Brugia malayi cahepsin L-like non-peptiedase homolog 0.023 0.0932 0.0926
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0146 0.058 0.1283
Trichomonas vaginalis calcium binding protein, putative 0.0027 0.0087 0.0223
Schistosoma mansoni cathepsin B (C01 family) 0.023 0.0932 0.0926
Trichomonas vaginalis calmodulin-2, putative 0.0027 0.0087 0.0223
Schistosoma mansoni opsin-like receptor 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0152 0.0605 0.0599
Entamoeba histolytica hypothetical protein, conserved 0.0028 0.009 0.0008
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0015 0.0008
Giardia lamblia Cathepsin L precursor 0.023 0.0932 0.2309
Brugia malayi Calmodulin-like protein 0.0027 0.0087 0.0081
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0019 0.0013
Plasmodium vivax serine-repeat antigen (SERA) 0.023 0.0932 0.2199
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0011 0.0019 0.0013
Brugia malayi G-protein coupled receptor 0.0011 0.0019 0.0013
Echinococcus multilocularis hypothetical protein 0.0146 0.058 0.0574
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0028 0.009 0.0084
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Loa Loa (eye worm) TYRA-2 protein 0.0011 0.0019 0.0013
Onchocerca volvulus 0.0011 0.0019 0.0012
Giardia lamblia Dipeptidyl-peptidase I precursor 0.023 0.0932 0.2309
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0414 0.1696 0.1691
Brugia malayi G-protein coupled receptor 0.0011 0.0019 0.0013
Brugia malayi EF hand family protein 0.0028 0.009 0.0084
Brugia malayi Cathepsin L-like precursor 0.095 0.3929 0.3925
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.023 0.0932 0.2199
Brugia malayi hypothetical protein 0.0011 0.0019 0.0013
Schistosoma mansoni neuronal calcium sensor 0.0027 0.0087 0.0081
Schistosoma mansoni biogenic amine receptor 0.0011 0.0019 0.0013
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0027 0.0087 0.0223
Onchocerca volvulus Matrilysin homolog 0.0022 0.0064 0.0124
Loa Loa (eye worm) hypothetical protein 0.0292 0.1189 0.1183
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0292 0.1189 0.1183
Entamoeba histolytica cysteine protease, putative 0.0522 0.2147 0.5362
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0015 0.0008
Echinococcus granulosus neuronal calcium sensor 0.0027 0.0087 0.0081
Trichomonas vaginalis calmodulin, putative 0.0027 0.0087 0.0223
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0019 0.0013
Schistosoma mansoni amine GPCR 0.0011 0.0019 0.0013
Echinococcus granulosus alpha 1A adrenergic receptor 0.0011 0.0019 0.0013
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0044 0.0156 0.0397
Onchocerca volvulus 0.0011 0.0019 0.0012
Echinococcus multilocularis cathepsin b 0.2409 1 1
Echinococcus granulosus neuropeptide receptor A26 0.0011 0.0019 0.0013
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0044 0.0156 0.0397
Schistosoma mansoni hypothetical protein 0.0015 0.0038 0.0031
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Echinococcus granulosus serotonin receptor 0.0011 0.0019 0.0013
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0015 0.0008
Trypanosoma brucei cysteine peptidase C (CPC) 0.0904 0.3737 0.9499
Brugia malayi calpain 5 0.0102 0.0398 0.0392
Trypanosoma cruzi major cysteine proteinase, putative 0.023 0.0932 0.0852
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0087 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.095 0.3929 1
Leishmania major cathepsin L-like protease 0.095 0.3929 1
Leishmania major cathepsin L-like protease 0.095 0.3929 1
Loa Loa (eye worm) G-protein coupled receptor 0.0011 0.0019 0.0013
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0011 0.0019 0.0013
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0146 0.058 0.0497
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0026 0.0083 0.0077
Trypanosoma brucei Calpain-like protein 2 0.0044 0.0156 0.0179
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Echinococcus granulosus tm gpcr rhodopsin 0.0011 0.0019 0.0013
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0027 0.0087 0.0081
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.009 0.0083
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.023 0.0932 0.0926
Entamoeba histolytica cysteine protease, putative 0.0522 0.2147 0.5362
Loa Loa (eye worm) hypothetical protein 0.0292 0.1189 0.1183
Onchocerca volvulus 0.0027 0.0087 0.0185
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.023 0.0932 0.0926
Trypanosoma cruzi conserved protein 0.0044 0.0156 0.0069
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0044 0.0156 0.0179
Brugia malayi AKH receptor 0.0011 0.0019 0.0013
Plasmodium falciparum serine repeat antigen 3 0.023 0.0932 0.2199
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0011 0.0019 0.0013
Loa Loa (eye worm) cathepsin B 0.0904 0.3737 0.3733
Trypanosoma brucei hypothetical protein 0.0044 0.0156 0.0179
Onchocerca volvulus 0.0011 0.0019 0.0012
Entamoeba histolytica cysteine protease, putative 0.0522 0.2147 0.5362
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0008
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0146 0.058 0.0497
Trichomonas vaginalis calcium binding protein, putative 0.0027 0.0087 0.0223
Echinococcus multilocularis neuropeptide receptor 0.0011 0.0019 0.0013
Trichomonas vaginalis calmodulin, putative 0.0027 0.0087 0.0223
Schistosoma mansoni adenoreceptor 0.0011 0.0019 0.0013
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0044 0.0156 0.0179
Schistosoma mansoni hypothetical protein 0.0331 0.1353 0.1347
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0011 0.0019 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.095 0.3929 1
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0132 0.0114
Echinococcus granulosus calumenin 0.0028 0.009 0.0084
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0044 0.0156 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.023 0.0932 0.2373
Onchocerca volvulus Cathepsin L homolog 0.095 0.3929 1
Brugia malayi Papain family cysteine protease containing protein 0.023 0.0932 0.0926
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0658 0.2714 0.2709
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0522 0.2147 0.2142
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Entamoeba histolytica cysteine protease, putative 0.023 0.0932 0.2199
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.023 0.0932 0.2199
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0022 0.0064 0.0057
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.023 0.0932 0.2199
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.023 0.0932 0.2373
Onchocerca volvulus 0.095 0.3929 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0011 0.0019 0.0013
Onchocerca volvulus Cathepsin F homolog 0.095 0.3929 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0011 0.0019 0.0013
Schistosoma mansoni neuronal calcium sensor 0.0027 0.0087 0.0081
Schistosoma mansoni hypothetical protein 0.0033 0.0113 0.0106
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Entamoeba histolytica cysteine proteinase, putative 0.0522 0.2147 0.5362
Trypanosoma cruzi kinesin, putative 0.0102 0.0398 0.0313
Onchocerca volvulus 0.0011 0.0019 0.0012
Echinococcus multilocularis g protein coupled receptor 0.0011 0.0019 0.0013
Trypanosoma brucei cysteine peptidase, putative 0.0044 0.0156 0.0179
Schistosoma mansoni myosin xvIII 0.0011 0.0019 0.0013
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0011 0.0019 0.0013
Plasmodium vivax vivapain-2 0.095 0.3929 1
Echinococcus multilocularis cpg binding protein 0.003 0.0097 0.009
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.023 0.0932 0.0926
Onchocerca volvulus 0.095 0.3929 1
Loa Loa (eye worm) hypothetical protein 0.095 0.3929 0.3925
Schistosoma mansoni hypothetical protein 0.0015 0.0038 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.095 0.3929 1
Onchocerca volvulus Matrix metalloproteinase homolog 0.0048 0.0173 0.0404
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0099 0.0031
Echinococcus multilocularis cathepsin b 0.2409 1 1
Plasmodium falciparum calpain 0.0044 0.0156 0.0179
Brugia malayi steroid hormone receptor 0.001 0.0015 0.0008
Brugia malayi cathepsin L-like cysteine proteinase 0.023 0.0932 0.0926
Trypanosoma cruzi cysteine peptidase, putative 0.095 0.3929 0.3876
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.095 0.3929 1
Toxoplasma gondii preprocathepsin c precursor, putative 0.023 0.0932 0.2199
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Loa Loa (eye worm) hypothetical protein 0.0044 0.0156 0.015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.095 0.3929 1
Giardia lamblia Cathepsin B precursor 0.023 0.0932 0.2309
Echinococcus multilocularis calpain A 0.0415 0.1699 0.1694
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.095 0.3929 1
Brugia malayi Cathepsin L-like precursor 0.095 0.3929 0.3925
Plasmodium falciparum cysteine proteinase falcipain 3 0.095 0.3929 1
Entamoeba histolytica cysteine protease, putative 0.0522 0.2147 0.5362
Echinococcus granulosus allatostatin A receptor 0.0011 0.0019 0.0013
Schistosoma mansoni biogenic amine receptor 0.0011 0.0019 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0099 0.0093
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0011 0.0019 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0015 0.0008
Plasmodium vivax unspecified product 0.023 0.0932 0.2199
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.095 0.3929 1
Onchocerca volvulus 0.0658 0.2714 0.6896
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.0561 0.0555
Brugia malayi Hemopexin family protein 0.0031 0.0101 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.095 0.3929 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0011 0.0019 0.0013
Brugia malayi follicle stimulating hormone receptor 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.023 0.0932 0.0926
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.095 0.3929 1
Entamoeba histolytica cysteine protease, putative 0.0522 0.2147 0.5362
Brugia malayi cathepsin Z-like cysteine proteinase 0.023 0.0932 0.0926
Schistosoma mansoni cathepsin S (C01 family) 0.023 0.0932 0.0926
Trypanosoma brucei calpain-like protein, putative 0.0146 0.058 0.1283
Brugia malayi CXXC zinc finger family protein 0.0028 0.009 0.0083
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0146 0.0373
Onchocerca volvulus 0.0028 0.009 0.0192
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2409 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.095 0.3929 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Echinococcus granulosus tm gpcr rhodopsin 0.0011 0.0019 0.0013
Echinococcus granulosus centrin 2 0.0027 0.0087 0.0081
Trypanosoma cruzi cruzipain precursor, putative 0.095 0.3929 0.3876
Onchocerca volvulus 0.003 0.0099 0.0216
Schistosoma mansoni calmodulin related calcium binding protein 0.0027 0.0087 0.0081
Entamoeba histolytica cysteine protease, putative 0.023 0.0932 0.2199
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0011 0.0019 0.0012
Schistosoma mansoni peptidyl-glycine monooxygenase 0.023 0.0931 0.0925
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0099 0.0093
Onchocerca volvulus 0.0011 0.0019 0.0012
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0027 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0008
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0414 0.1696 0.1691
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0026 0.0083 0.5
Echinococcus granulosus cpg binding protein 0.003 0.0097 0.009
Entamoeba histolytica cysteine protease, putative 0.0522 0.2147 0.5362
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0011 0.0019 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.095 0.3929 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0015 0.0008
Schistosoma mansoni calpain C (C02 family) 0.0146 0.058 0.0574
Onchocerca volvulus 0.095 0.3929 1
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0015 0.0008
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.023 0.0932 0.0926
Trichomonas vaginalis calcium binding proteins, putative 0.0027 0.0087 0.0223
Trichomonas vaginalis calcium binding protein, putative 0.0027 0.0087 0.0223
Schistosoma mansoni hypothetical protein 0.0015 0.0038 0.0031
Trypanosoma brucei Calpain-like protein CALP1.3 0.0044 0.0156 0.0179
Leishmania major hypothetical protein, unknown function 0.0044 0.0156 0.0179
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.095 0.3929 1
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0015 0.0008
Brugia malayi neuropeptide F receptor 0.0011 0.0019 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.095 0.3929 1
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.023 0.0932 0.2199
Echinococcus multilocularis neurocalcin 0.0027 0.0087 0.0081
Echinococcus granulosus geminin 0.0331 0.1353 0.1347
Schistosoma mansoni hypothetical protein 0.0011 0.0019 0.0013
Trichomonas vaginalis calpain, putative 0.0044 0.0156 0.0397
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.023 0.0932 0.0926
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.023 0.0932 0.2373
Schistosoma mansoni coup transcription factor 0.001 0.0015 0.0008
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.095 0.3929 0.3925
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0015 0.0008
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0038 0.0031
Echinococcus multilocularis cathepsin L 0.023 0.0932 0.0926
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0522 0.2147 0.5362
Onchocerca volvulus 0.0011 0.0019 0.0012
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0027 0.0087 0.0081
Echinococcus granulosus calbindin 32 0.0028 0.009 0.0084
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0038 0.0031
Entamoeba histolytica cysteine protease, putative 0.0522 0.2147 0.5362
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Echinococcus granulosus cathepsin l cysteine peptidase 0.095 0.3929 0.3925
Schistosoma mansoni neuropeptide receptor 0.0011 0.0019 0.0013
Onchocerca volvulus 0.095 0.3929 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0011 0.0019 0.0013
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0014 0.0007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Onchocerca volvulus 0.095 0.3929 1
Brugia malayi fibroinase precursor 0.023 0.0932 0.0926
Plasmodium vivax serine-repeat antigen (SERA) 0.023 0.0932 0.2199
Leishmania major cathepsin L-like protease 0.095 0.3929 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0285 0.1158 0.1152
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.095 0.3929 1
Schistosoma mansoni hypothetical protein 0.0027 0.0087 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.095 0.3929 1
Echinococcus granulosus EF hand domain containing family member A2 0.0028 0.009 0.0084
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0015 0.0008
Entamoeba histolytica cysteine protease, putative 0.023 0.0932 0.2199
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0011 0.0019 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0099 0.0093
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0008
Onchocerca volvulus Cathepsin L homolog 0.023 0.0932 0.2344
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0386 0.1582 0.1577
Entamoeba histolytica cysteine protease, putative 0.095 0.3929 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0044 0.0156 0.0069
Plasmodium vivax serine-repeat antigen (SERA), putative 0.023 0.0932 0.2199
Trypanosoma brucei calpain-like protein, putative 0.0146 0.058 0.1283
Schistosoma mansoni neuropeptide receptor 0.0011 0.0019 0.0013
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0015 0.0008
Brugia malayi Cathepsin L-like precursor 0.0658 0.2714 0.2709
Trichomonas vaginalis calmodulin, putative 0.0027 0.0087 0.0223
Plasmodium falciparum serine repeat antigen 7 0.023 0.0932 0.2199
Echinococcus granulosus 7TM GPCR rhodopsin 0.0011 0.0019 0.0013
Loa Loa (eye worm) calpain D 0.0044 0.0156 0.015
Giardia lamblia Hypothetical protein 0.023 0.0932 0.2309
Onchocerca volvulus 0.095 0.3929 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.023 0.0932 0.2199
Trypanosoma brucei calpain-like protein, putative 0.0146 0.058 0.1283
Leishmania major cathepsin L-like protease 0.095 0.3929 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.095 0.3929 1
Brugia malayi putative neuropeptide receptor NPR1 0.0011 0.0019 0.0013
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0015 0.0008
Echinococcus granulosus neuropeptides capa receptor 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Brugia malayi Cathepsin L-like precursor 0.095 0.3929 0.3925
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0027 0.0087 0.0223
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0132 0.0116
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.023 0.0932 0.2373
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0099 0.0093
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Brugia malayi calpain family protein 1 0.0386 0.1582 0.1577
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0132 0.0116
Echinococcus multilocularis neuropeptides capa receptor 0.0011 0.0019 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.095 0.3929 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0904 0.3737 0.3681
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0079 0.0301 0.0294
Brugia malayi Cathepsin L-like precursor 0.0292 0.1189 0.1183
Trichomonas vaginalis calmodulin, putative 0.0027 0.0087 0.0223
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0044 0.0156 0.0069
Echinococcus multilocularis g-protein coupled receptor 0.0011 0.0019 0.0013
Schistosoma mansoni thyroid hormone receptor 0.001 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0008
Trypanosoma cruzi cysteine protease, putative 0.0522 0.2147 0.2078
Trypanosoma brucei Calpain-like protein 1.1 0.0044 0.0156 0.0179
Echinococcus multilocularis serotonin receptor 0.0152 0.0605 0.0599
Echinococcus granulosus tachykinin peptides receptor 99D 0.0011 0.0019 0.0013
Plasmodium vivax calpain, putative 0.0146 0.058 0.1283
Brugia malayi Serotonin receptor 0.0011 0.0019 0.0013
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0146 0.0153
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0044 0.0156 0.0069
Echinococcus granulosus fmrfamide receptor 0.0011 0.0019 0.0013
Schistosoma mansoni neuropeptide f receptor 76f 0.0011 0.0019 0.0013
Entamoeba histolytica cysteine protease, putative 0.0522 0.2147 0.5362
Schistosoma mansoni dopamine-beta-monooxygenase 0.0122 0.0482 0.0476
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0.0019 0.0013
Schistosoma mansoni hypothetical protein 0.0044 0.0156 0.015
Loa Loa (eye worm) hypothetical protein 0.023 0.0932 0.0926
Schistosoma mansoni centrin-related 0.0027 0.0087 0.0081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0159 0.0153
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.023 0.0931 0.0925
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0522 0.2147 0.5465
Echinococcus multilocularis fmrfamide receptor 0.0011 0.0019 0.0013
Brugia malayi Papain family cysteine protease containing protein 0.0522 0.2147 0.2142
Loa Loa (eye worm) calpain family protein 1 0.0386 0.1582 0.1577
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0011 0.0019 0.0013
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0044 0.0156 0.0069
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0011 0.0019 0.0013
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Echinococcus granulosus somatostatin receptor 0.0011 0.0019 0.0013
Leishmania major kinesin, putative 0.0102 0.0398 0.0808
Schistosoma mansoni rab 0.0027 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Mycobacterium ulcerans hydrolase 0.0026 0.0083 0.5
Trichomonas vaginalis centrin, putative 0.0027 0.0087 0.0223
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.095 0.3929 1
Loa Loa (eye worm) EF hand family protein 0.0027 0.0087 0.0081
Trypanosoma cruzi cysteine peptidase, putative 0.095 0.3929 0.3876
Echinococcus granulosus g protein coupled receptor 0.0011 0.0019 0.0013
Brugia malayi hypothetical protein 0.0011 0.0019 0.0013
Brugia malayi hypothetical protein 0.0011 0.0019 0.0013
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0458 0.0452
Echinococcus granulosus calcium uptake protein 1 0.0028 0.009 0.0084
Trypanosoma brucei calmodulin, putative 0.0028 0.009 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.095 0.3929 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0044 0.0156 0.0397
Leishmania major cathepsin L-like protease 0.095 0.3929 1
Loa Loa (eye worm) hypothetical protein 0.0241 0.0975 0.0969
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.023 0.0932 0.2199
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0015 0.0008
Brugia malayi Melatonin receptor type 1A 0.0011 0.0019 0.0013
Leishmania major calpain protease-like protein 0.0044 0.0156 0.0179
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0159 0.0153
Echinococcus multilocularis programmed cell death protein 0.0027 0.0087 0.0081
Brugia malayi cathepsin F-like cysteine proteinase 0.0292 0.1189 0.1183
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0522 0.2147 0.2078
Brugia malayi nuclear hormone receptor 0.001 0.0015 0.0008
Echinococcus multilocularis dnaJ subfamily B 0.0398 0.1632 0.1626
Echinococcus multilocularis neuropeptide Y receptor 0.0011 0.0019 0.0013
Loa Loa (eye worm) programmed cell death protein 6 0.0028 0.009 0.0084
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0458 0.0452
Trypanosoma brucei calpain, putative 0.0044 0.0156 0.0179
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0044 0.0156 0.0069
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0044 0.0156 0.0397
Brugia malayi ecdysteroid receptor 0.001 0.0015 0.0008
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0015 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0015 0.0008
Plasmodium falciparum cysteine proteinase falcipain 2b 0.095 0.3929 1
Loa Loa (eye worm) hypothetical protein 0.0658 0.2714 0.2709
Echinococcus multilocularis neuropeptide FF receptor 2 0.0011 0.0019 0.0013
Echinococcus granulosus orexin receptor type 2 0.0011 0.0019 0.0013
Echinococcus multilocularis allatostatin A receptor 0.0011 0.0019 0.0013
Echinococcus multilocularis calpain 5 0.0146 0.058 0.0574
Trypanosoma cruzi cysteine peptidase, putative 0.095 0.3929 0.3876
Schistosoma mansoni neuropeptide F-like receptor 0.0011 0.0019 0.0013
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0658 0.2714 0.265
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0011 0.0019 0.0013
Brugia malayi Papain family cysteine protease containing protein 0.023 0.0932 0.0926
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Schistosoma mansoni hypothetical protein 0.0331 0.1353 0.1347
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0015 0.0008
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0038 0.0031
Echinococcus multilocularis neuropeptide receptor 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0008
Echinococcus granulosus cathepsin L 0.0522 0.2147 0.2142
Echinococcus multilocularis g protein coupled receptor 0.0011 0.0019 0.0013
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0087 0.0223
Schistosoma mansoni peptidylglycine monooxygenase 0.0122 0.0482 0.0476
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0019 0.0013
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0015 0.0008
Onchocerca volvulus 0.0236 0.0954 0.24
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0015 0.0008
Loa Loa (eye worm) matrixin family protein 0.0048 0.0173 0.0167
Echinococcus multilocularis calcium uptake protein 1 0.0028 0.009 0.0084
Onchocerca volvulus 0.0011 0.0019 0.0012
Echinococcus granulosus neuropeptides capa receptor 0.0011 0.0019 0.0013
Plasmodium falciparum cysteine proteinase falcipain 2a 0.095 0.3929 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.095 0.3929 1
Trichomonas vaginalis calmodulin, putative 0.0027 0.0087 0.0223
Echinococcus multilocularis somatostatin receptor 0.0011 0.0019 0.0013
Echinococcus multilocularis cysteine protease 0.095 0.3929 0.3925
Trypanosoma brucei calpain-like protein, putative 0.0146 0.058 0.1283
Brugia malayi Matrixin family protein 0.0052 0.0191 0.0185
Trichomonas vaginalis hypothetical protein 0.0044 0.0156 0.0397
Echinococcus granulosus neuropeptide FF receptor 2 0.0011 0.0019 0.0013
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0146 0.058 0.0497
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.023 0.0932 0.0926
Entamoeba histolytica cysteine protease, putative 0.0522 0.2147 0.5362
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0011 0.0019 0.0013
Onchocerca volvulus 0.023 0.0932 0.2344
Trypanosoma cruzi kinesin, putative 0.0102 0.0398 0.0313
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0225 0.0219
Schistosoma mansoni calpain-7 (C02 family) 0.0146 0.058 0.0574
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0022 0.0064 0.0057
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0152 0.0605 0.0599
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0099 0.0093
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Trypanosoma brucei antigen, putative 0.0146 0.058 0.1283
Echinococcus multilocularis neuropeptide receptor A26 0.0011 0.0019 0.0013
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2409 1 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0038 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.095 0.3929 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0213 0.0327
Echinococcus multilocularis fmrfamide receptor 0.0011 0.0019 0.0013
Brugia malayi Pre-SET motif family protein 0.003 0.0099 0.0093
Giardia lamblia Cathepsin B precursor 0.023 0.0932 0.2309
Toxoplasma gondii cathepsin CPC2 0.023 0.0932 0.2199
Schistosoma mansoni cpg binding protein 0.003 0.0097 0.009
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0122 0.0482 0.0476
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0011 0.0019 0.0013
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0015 0.0008
Mycobacterium leprae PROBABLE HYDROLASE 0.0026 0.0083 0.5
Plasmodium vivax unspecified product 0.0292 0.1189 0.2866
Brugia malayi Dopamine receptor protein 2 0.0011 0.0019 0.0013
Plasmodium vivax SET domain protein, putative 0.003 0.0099 0.0031
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0.0019 0.0013
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0146 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.095 0.3929 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0038 0.0031
Entamoeba histolytica cysteine proteinase 2 0.0522 0.2147 0.5362
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.023 0.0932 0.2373
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0019 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0904 0.3737 0.951
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.023 0.0931 0.0925
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0122 0.0482 0.0476
Loa Loa (eye worm) hypothetical protein 0.0292 0.1189 0.1183
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.095 0.3929 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0159 0.0153
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0159 0.0153
Trypanosoma cruzi cysteine peptidase, putative 0.0292 0.1189 0.1111
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Loa Loa (eye worm) hypothetical protein 0.023 0.0932 0.0926
Toxoplasma gondii calcium-dependent protein kinase 0.0028 0.009 0.0008
Trypanosoma cruzi major cysteine proteinase, putative 0.023 0.0932 0.0852
Echinococcus granulosus neuropeptide Y receptor 0.0011 0.0019 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0015 0.0008
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0015 0.0008
Echinococcus granulosus biogenic amine 5HT receptor 0.0011 0.0019 0.0013
Plasmodium falciparum cysteine proteinase falcipain 1 0.0522 0.2147 0.5362
Echinococcus granulosus neuropeptide s receptor 0.0011 0.0019 0.0013
Entamoeba histolytica cysteine protease, putative 0.0522 0.2147 0.5362
Schistosoma mansoni neuropeptide F-like receptor 0.0011 0.0019 0.0013
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Loa Loa (eye worm) calpain family protein 1 0.0285 0.1158 0.1152
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Echinococcus multilocularis G-protein coupled receptor, putative 0.0011 0.0019 0.0013
Entamoeba histolytica protein kinase, putative 0.0102 0.0398 0.0808
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0658 0.2714 0.6908
Entamoeba histolytica cysteine proteinase, putative 0.095 0.3929 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0019 0.0013
Brugia malayi hypothetical protein 0.0011 0.0019 0.0013
Onchocerca volvulus 0.0241 0.0975 0.2454
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Echinococcus granulosus GPCR family 2 0.0015 0.0038 0.0031
Brugia malayi Dopamine receptor 0.0011 0.0019 0.0013
Entamoeba histolytica cysteine protease, putative 0.023 0.0932 0.2199
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0177 0.0171
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0015 0.0008
Trypanosoma brucei kinesin, putative 0.0102 0.0398 0.0808
Schistosoma mansoni cathepsin F (C01 family) 0.095 0.3929 0.3925
Brugia malayi Dopamine receptor protein 1 0.0011 0.0019 0.0013
Echinococcus multilocularis orexin receptor type 2 0.0011 0.0019 0.0013
Leishmania major cathepsin L-like protease 0.095 0.3929 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0011 0.0019 0.0013
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0011 0.0019 0.0013
Echinococcus multilocularis cathepsin L cysteine protease 0.095 0.3929 0.3925
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.095 0.3929 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0044 0.0156 0.0397
Onchocerca volvulus 0.0022 0.0064 0.0124
Echinococcus granulosus neuropeptide receptor 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0049 0.0177 0.0171
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0044 0.0156 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.095 0.3929 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Brugia malayi Serotonin receptor 0.0011 0.0019 0.0013
Plasmodium falciparum serine repeat antigen 1 0.023 0.0932 0.2199
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.095 0.3929 1
Trypanosoma cruzi cruzipain precursor, putative 0.0292 0.1189 0.1111
Brugia malayi Matrixin family protein 0.0022 0.0064 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0658 0.2714 0.6908
Trichomonas vaginalis conserved hypothetical protein 0.023 0.0932 0.2373
Echinococcus granulosus dro:myosuppressin receptor 0.0011 0.0019 0.0013
Onchocerca volvulus 0.0011 0.0019 0.0012
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0027 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0015 0.0008
Echinococcus multilocularis calmodulin 0.0027 0.0087 0.0081
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0069
Echinococcus granulosus calpain 0.0146 0.058 0.0574
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0146 0.0153
Schistosoma mansoni calpain (C02 family) 0.0146 0.058 0.0574
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.0561 0.0555
Giardia lamblia Hypothetical protein 0.023 0.0932 0.2309
Schistosoma mansoni calmodulin 0.0027 0.0087 0.0081
Trichomonas vaginalis calcineurin B subunit, putative 0.0028 0.009 0.023
Echinococcus granulosus cathepsin b 0.2409 1 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0011 0.0019 0.0013
Schistosoma mansoni amine GPCR 0.0011 0.0019 0.0013
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0011 0.0019 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.023 0.0932 0.2373
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Giardia lamblia Cathepsin L-like protease 0.023 0.0932 0.2309
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0522 0.2147 0.5465
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0159 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.023 0.0932 0.2373
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0179
Entamoeba histolytica cysteine proteinase, putative 0.095 0.3929 1
Entamoeba histolytica cysteine proteinase, putative 0.0658 0.2714 0.6837
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0386 0.1582 0.1577
Loa Loa (eye worm) hypothetical protein 0.023 0.0932 0.0926
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.095 0.3929 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.023 0.0932 0.2373
Brugia malayi cathepsin L-like precursor 0.0658 0.2714 0.2709
Loa Loa (eye worm) cysteine protease 0.095 0.3929 0.3925
Schistosoma mansoni amine GPCR 0.0011 0.0019 0.0013
Brugia malayi sulfakinin receptor protein 0.0011 0.0019 0.0013
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0044 0.0156 0.0069
Onchocerca volvulus 0.0011 0.0019 0.0012
Trichomonas vaginalis set domain proteins, putative 0.0236 0.0954 0.2429
Echinococcus multilocularis cathepsin l cysteine peptidase 0.095 0.3929 0.3925
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0014 0.0008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0.0019 0.0013
Giardia lamblia Cysteine protease 0.023 0.0932 0.2309
Brugia malayi hypothetical protein 0.0011 0.0019 0.0013
Onchocerca volvulus 0.095 0.3929 1
Trichomonas vaginalis calpain, putative 0.0044 0.0156 0.0397
Schistosoma mansoni hypothetical protein 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0026 0.0083 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0015 0.0008
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0011 0.0019 0.0013
Leishmania major hypothetical protein, conserved 0.0044 0.0156 0.0179
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.023 0.0932 0.2199
Trichomonas vaginalis calmodulin, putative 0.0027 0.0087 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.095 0.3929 1
Giardia lamblia Cysteine protease 0.023 0.0932 0.2309
Trypanosoma cruzi cysteine peptidase, putative 0.0522 0.2147 0.2078
Echinococcus multilocularis EF hand domain containing family member A2 0.0028 0.009 0.0084
Entamoeba histolytica cysteine protease, putative 0.0522 0.2147 0.5362
Echinococcus granulosus neuropeptide Y receptor 0.0011 0.0019 0.0013
Trichomonas vaginalis calpain, putative 0.0044 0.0156 0.0397
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.095 0.3929 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0156 0.0069
Loa Loa (eye worm) hypothetical protein 0.0343 0.14 0.1394
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0038 0.0031
Brugia malayi Papain family cysteine protease containing protein 0.023 0.0932 0.0926
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0146 0.014
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.023 0.0932 0.2373
Echinococcus granulosus G protein coupled receptor 139 0.0011 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.095 0.3929 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 101.8 ug ml-1 Antibacterial activity against Escherichia coli assessed as survival after 24 hrs by MTT assay ChEMBL. 23770447

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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