TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 373.436 | Formula: C17H22F3N3OS
H donors: 1 H acceptors: 2 LogP: 4.52 Rotable bonds: 8
Rule of 5 violations (Lipinski): 1
SMILES: CC(CCC(c1sccc1NC(=O)c1cn(nc1C(F)(F)F)C)C)C
InChi: 1S/C17H22F3N3OS/c1-10(2)5-6-11(3)14-13(7-8-25-14)21-16(24)12-9-23(4)22-15(12)17(18,19)20/h7-11H,5-6H2,1-4H3,(H,21,24)
InChiKey: JLUIDEVPLCSUIV-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma cruzi	mitogen activated protein kinase 4, putative	0.0057	0.0019	0.0043
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0053	0.0013	0.0029
Loa Loa (eye worm)	TK/FER protein kinase	0.0053	0.0013	0.0002
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.0055	0.0016	0.0006
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0134	0.0136	0.2563
Echinococcus granulosus	tyrosine protein kinase csk	0.0053	0.0013	0.0013
Loa Loa (eye worm)	zinc metallopeptidase 4	0.0071	0.004	0.003
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0096	0.0078	0.0078
Schistosoma mansoni	tyrosine kinase	0.0103	0.0089	0.0089
Echinococcus granulosus	histone deacetylase	0.0693	0.0981	0.0981
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0053	0.0013	0.0029
Trichomonas vaginalis	histone deacetylase, putative	0.0796	0.1137	0.2549
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Plasmodium vivax	histone deacetylase 1, putative	0.0796	0.1137	1
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0053	0.0013	0.0013
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0053	0.0013	0.0029
Loa Loa (eye worm)	TK/ALK protein kinase	0.0053	0.0013	0.0002
Trichomonas vaginalis	phopsphatidylinositol 3-kinase, drosophila, putative	0.2969	0.4424	1
Echinococcus granulosus	kinase suppressor of Ras 1	0.0053	0.0013	0.0013
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Brugia malayi	Tyrosine-protein kinase abl-1	0.0135	0.0137	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0136	0.0139	0.0129
Schistosoma mansoni	dopamine-beta-monooxygenase	0.0122	0.0118	0.0118
Loa Loa (eye worm)	TK/FER protein kinase	0.0053	0.0013	0.0002
Echinococcus granulosus	histone deacetylase 6	0.0709	0.1005	0.1005
Trichomonas vaginalis	histone deacetylase, putative	0.0796	0.1137	0.2549
Entamoeba histolytica	serine/threonine kinase, putative	0.0053	0.0013	0.0029
Echinococcus multilocularis	epidermal growth factor receptor	0.6656	1	1
Trypanosoma brucei	FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative	0.0134	0.0136	0.0332
Loa Loa (eye worm)	TK/FER protein kinase	0.0053	0.0013	0.0002
Trypanosoma cruzi	protein kinase, putative	0.0053	0.0013	0.0029
Echinococcus multilocularis	insulin receptor	0.2135	0.3163	0.3163
Brugia malayi	Tyrosyl-DNA phosphodiesterase family protein	0.007	0.0039	0.0028
Leishmania major	phosphatidylinositol kinase related protein, putative	0.0134	0.0136	0.0332
Brugia malayi	C-terminal src kinase protein 1	0.0053	0.0013	0.0001
Onchocerca volvulus		0.0134	0.0136	0.0918
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0098	0.0081	0.0081
Loa Loa (eye worm)	TK/FER protein kinase	0.0053	0.0013	0.0002
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Loa Loa (eye worm)	TK protein kinase	0.0053	0.0013	0.0002
Echinococcus granulosus	neuroglian	0.0052	0.0011	0.0011
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0053	0.0013	0.0002
Leishmania major	phosphatidylinositol kinase, putative	0.0134	0.0136	0.0332
Toxoplasma gondii	target of rapamycin (TOR), putative	0.0134	0.0136	0.0332
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Echinococcus multilocularis	microtubule associated protein 2	0.0731	0.1039	0.1039
Entamoeba histolytica	phosphatidylinositol-4,5-bisphosphate 3-kinase, putative	0.0591	0.0826	0.1868
Schistosoma mansoni	protein tyrosine kinase	0.0053	0.0013	0.0013
Entamoeba histolytica	phosphatidylinositol 3-kinase 1, putative	0.2835	0.4221	0.9541
Echinococcus granulosus	tyrosine kinase	0.0065	0.0031	0.0031
Brugia malayi	Protein kinase domain containing protein	0.0065	0.0031	0.002
Toxoplasma gondii	protein kinase	0.0053	0.0013	0.0031
Loa Loa (eye worm)	hypothetical protein	0.0091	0.007	0.006
Loa Loa (eye worm)	thymidylate synthase	0.008	0.0054	0.0044
Echinococcus granulosus	thymidylate synthase	0.008	0.0054	0.0054
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0036	0.0026
Echinococcus granulosus	mitogen activated protein kinase 3	0.0057	0.0019	0.0019
Schistosoma mansoni	histone deacetylase 1 2 3	0.0337	0.0442	0.0442
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0053	0.0013	0.0013
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor2	0.0134	0.0136	0.0307
Echinococcus granulosus	DNA dependent protein kinase catalytic subunit	0.0134	0.0136	0.0136
Loa Loa (eye worm)	TK/Met protein kinase	0.0053	0.0013	0.0002
Schistosoma mansoni	protein kinase	0.0053	0.0013	0.0013
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0103	0.0089	0.0089
Echinococcus granulosus	serine:threonine protein kinase SMG1	0.0134	0.0136	0.0136
Leishmania major	protein kinase, putative	0.0056	0.0018	0.0043
Mycobacterium tuberculosis	Probable zinc metalloprotease Zmp1	0.0291	0.0374	1
Loa Loa (eye worm)	TK protein kinase	0.0084	0.0059	0.0049
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0053	0.0013	0.0001
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0056	0.0018	0.004
Echinococcus multilocularis	neuroglian	0.0052	0.0011	0.0011
Plasmodium falciparum	phosphatidylinositol 4-kinase	0.0134	0.0136	0.1196
Giardia lamblia	Hypothetical protein	0.0134	0.0136	0.0382
Toxoplasma gondii	bifunctional dihydrofolate reductase-thymidylate synthase	0.0113	0.0103	0.0253
Echinococcus multilocularis	histone deacetylase	0.0693	0.0981	0.0981
Schistosoma mansoni	hypothetical protein	0.0076	0.0048	0.0048
Loa Loa (eye worm)	CMGC/MAPK/ERK1 protein kinase	0.0057	0.0019	0.0009
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0053	0.0013	0.0002
Echinococcus multilocularis	leukotriene A 4 hydrolase	0.0239	0.0294	0.0294
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Trypanosoma cruzi	histone deacetylase, putative	0.0693	0.0981	0.2218
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0053	0.0013	0.0001
Schistosoma mansoni	hypothetical protein	0.0076	0.0048	0.0048
Echinococcus granulosus	protein kinase	0.0053	0.0013	0.0013
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0053	0.0013	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0112	0.0103	0.0092
Entamoeba histolytica	tyrosin kinase, putative	0.0053	0.0013	0.0029
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Loa Loa (eye worm)	hypothetical protein	0.0144	0.0151	0.0141
Trypanosoma cruzi	histone deacetylase, putative	0.0337	0.0442	0.0999
Trypanosoma brucei	histone deacetylase, putative	0.0693	0.0981	0.2399
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0118	0.0108
Loa Loa (eye worm)	hypothetical protein	0.023	0.0281	0.0271
Echinococcus granulosus	histone deacetylase 3	0.0796	0.1137	0.1137
Trypanosoma cruzi	phosphatidylinositol 3-kinase, putative	0.0134	0.0136	0.0307
Mycobacterium ulcerans	thymidylate synthase	0.008	0.0054	0.1446
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Loa Loa (eye worm)	peptidase family M13 containing protein	0.0215	0.0259	0.0249
Schistosoma mansoni	ephrin receptor	0.0061	0.0025	0.0025
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0284	0.0362	0.0362
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.2969	0.4424	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0053	0.0013	0.0029
Trypanosoma cruzi	fructose-1,6-bisphosphatase, cytosolic, putative	0.2749	0.4091	0.9248
Entamoeba histolytica	hypothetical protein	0.0134	0.0136	0.0307
Giardia lamblia	Phosphatidylinositol 4-kinase	0.0134	0.0136	0.0382
Plasmodium vivax	phosphatidylinositol 3- and 4-kinase, putative	0.0134	0.0136	0.1196
Leishmania major	tyrosyl-DNA phosphodiesterase 1	0.007	0.0039	0.0095
Trypanosoma cruzi	phosphatidylinositol 3-kinase vps34-like	0.0899	0.1293	0.2922
Schistosoma mansoni	protein kinase	0.0053	0.0013	0.0013
Schistosoma mansoni	protein kinase	0.0053	0.0013	0.0013
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0284	0.0362	0.0362
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.007	0.0039	0.0088
Trypanosoma cruzi	histone deacetylase, putative	0.0693	0.0981	0.2218
Schistosoma mansoni	histone deacetylase 4 5	0.0693	0.0981	0.0981
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0053	0.0013	0.0013
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0053	0.0013	0.0029
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0013	0.0002
Schistosoma mansoni	Nep2 peptidase (M13 family)	0.0147	0.0155	0.0155
Echinococcus granulosus	tyrosine protein kinase pr2	0.0053	0.0013	0.0013
Plasmodium vivax	bifunctional dihydrofolate reductase-thymidylate synthase, putative	0.0113	0.0103	0.091
Echinococcus multilocularis	protein kinase	0.0053	0.0013	0.0013
Toxoplasma gondii	histone deacetylase HDAC1	0.0693	0.0981	0.2399
Entamoeba histolytica	hypothetical protein	0.0053	0.0013	0.0029
Echinococcus granulosus	histone deacetylase 6	0.0693	0.0981	0.0981
Schistosoma mansoni	protein kinase	0.0056	0.0018	0.0018
Plasmodium vivax	histone deacetylase, putative	0.0693	0.0981	0.8632
Echinococcus granulosus	activated cdc42 kinase 1	0.0053	0.0013	0.0013
Echinococcus multilocularis	roundabout 2	0.012	0.0115	0.0115
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Echinococcus granulosus	phosphatidylinositol 4 kinase beta	0.0134	0.0136	0.0136
Echinococcus granulosus	histone deacetylase 7	0.0693	0.0981	0.0981
Loa Loa (eye worm)	hypothetical protein	0.0215	0.0259	0.0249
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0053	0.0013	0.0002
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Leishmania major	hypothetical protein, unknown function	0.0134	0.0136	0.0332
Brugia malayi	MAP kinase sur-1	0.0057	0.0019	0.0008
Echinococcus multilocularis	neuroglian	0.009	0.0069	0.0069
Schistosoma mansoni	tyrosine kinase	0.0097	0.0079	0.0079
Entamoeba histolytica	hypothetical protein	0.0134	0.0136	0.0307
Leishmania major	histone deacetylase, putative	0.0796	0.1137	0.2779
Schistosoma mansoni	hypothetical protein	0.0076	0.0048	0.0048
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0052	0.0011	0.0011
Plasmodium falciparum	histone deacetylase 1	0.0796	0.1137	1
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.007	0.0039	0.0088
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0052	0.0011	0.0001
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0053	0.0013	0.0013
Onchocerca volvulus		0.021	0.025	0.177
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0013	0.0002
Echinococcus granulosus	leukotriene A 4 hydrolase	0.0239	0.0294	0.0294
Schistosoma mansoni	ataxia telangiectasia mutated (atm)	0.0134	0.0136	0.0136
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Echinococcus granulosus	endothelin converting enzyme 1	0.0291	0.0374	0.0374
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0053	0.0013	0.0112
Echinococcus granulosus	ephrin type A receptor 4 A	0.0276	0.0351	0.0351
Trypanosoma cruzi	phosphatidylinositol 3-kinase 2, putative	0.2969	0.4424	1
Trichomonas vaginalis	histone deacetylase, putative	0.0796	0.1137	0.2549
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Echinococcus multilocularis	mitogen activated protein kinase 11	0.0402	0.0541	0.0541
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0053	0.0013	0.0013
Brugia malayi	Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein	0.006	0.0024	0.0013
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Plasmodium falciparum	phosphatidylinositol 3- and 4-kinase, putative	0.0134	0.0136	0.1196
Echinococcus multilocularis	endothelin converting enzyme 1	0.0291	0.0374	0.0374
Toxoplasma gondii	sedoheptulose-1,7-bisphosphatase	0.1022	0.1479	0.3616
Echinococcus granulosus	insulin receptor	0.2135	0.3163	0.3163
Schistosoma mansoni	serine/threonine protein kinase	0.0057	0.0019	0.0019
Schistosoma mansoni	tyrosine kinase	0.0065	0.0031	0.0031
Schistosoma mansoni	hypothetical protein	0.0076	0.0048	0.0048
Loa Loa (eye worm)	TK/ABL protein kinase	0.0284	0.0362	0.0352
Toxoplasma gondii	fructose-bisphospatase I	0.1022	0.1479	0.3616
Schistosoma mansoni	nephrin	0.0098	0.0081	0.0081
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Toxoplasma gondii	histone deacetylase HDAC3	0.0796	0.1137	0.2779
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.1063	0.1541	0.3484
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.101	0.146	0.1451
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Loa Loa (eye worm)	phosphatidylinositol kinase	0.0134	0.0136	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0065	0.0031	0.0021
Echinococcus multilocularis	DNA dependent protein kinase catalytic subunit	0.0134	0.0136	0.0136
Loa Loa (eye worm)	phosphatidylinositol 3	0.0134	0.0136	0.0126
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Schistosoma mansoni	cell adhesion molecule	0.0052	0.0011	0.0011
Entamoeba histolytica	hypothetical protein	0.0053	0.0013	0.0029
Plasmodium vivax	phosphatidylinositol 3-kinase, putative	0.0591	0.0826	0.7268
Echinococcus granulosus	tyrosine protein kinase HCK	0.0084	0.0059	0.0059
Leishmania major		0.2749	0.4091	1
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0276	0.0351	0.0351
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Loa Loa (eye worm)	histone deacetylase 3	0.0796	0.1137	0.1128
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Toxoplasma gondii	fructose-bisphospatase II	0.2749	0.4091	1
Schistosoma mansoni	neuroglian	0.0052	0.0011	0.0011
Echinococcus multilocularis	histone deacetylase 7	0.0693	0.0981	0.0981
Brugia malayi	hypothetical protein	0.011	0.0099	0.0088
Trypanosoma brucei	protein kinase, putative	0.0056	0.0018	0.0043
Schistosoma mansoni	vesicular amine transporter	0.0068	0.0036	0.0036
Schistosoma mansoni	tyrosine kinase	0.0103	0.0089	0.0089
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0013	0.0002
Schistosoma mansoni	protein kinase	0.0053	0.0013	0.0013
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Echinococcus granulosus	peptidyl glycine alpha amidating monooxygenase	0.023	0.0281	0.0281
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Leishmania major	dihydrofolate reductase-thymidylate synthase	0.0113	0.0103	0.0253
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0065	0.0031	0.0031
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0056	0.0018	0.0043
Schistosoma mansoni	nephrin	0.0052	0.0011	0.0011
Entamoeba histolytica	serine/threonine kinase, putative	0.0053	0.0013	0.0029
Echinococcus multilocularis	phosphatidylinositol 4,5 bisphosphate 3 kinase	0.4299	0.6435	0.6435
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.2969	0.4424	0.4417
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.4299	0.6435	0.6435
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0013	0.0002
Echinococcus granulosus	Immunoglobulin	0.0068	0.0036	0.0036
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0053	0.0013	0.0002
Toxoplasma gondii	phosphatidylinositol 3- and 4-kinase	0.0134	0.0136	0.0332
Trypanosoma brucei	phosphatidylinositol 4-kinase, putative	0.0134	0.0136	0.0332
Entamoeba histolytica	tyrosyl-DNA phosphodiesterase, putative	0.007	0.0039	0.0088
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative	0.0899	0.1293	0.2902
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Trypanosoma cruzi	histone deacetylase 1, putative	0.0796	0.1137	0.257
Echinococcus granulosus	activated cdc42 kinase 1	0.0053	0.0013	0.0013
Schistosoma mansoni	protein kinase	0.0053	0.0013	0.0013
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Trypanosoma brucei	mitogen-activated protein kinase 3, putative	0.0402	0.0541	0.1323
Plasmodium falciparum	protein kinase, putative	0.0053	0.0013	0.0112
Trypanosoma cruzi	phosphatidylinositol kinase, putative	0.0134	0.0136	0.0307
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0076	0.0048	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0013	0.0002
Plasmodium vivax	phosphatidylinositol 4-kinase, putative	0.0134	0.0136	0.1196
Onchocerca volvulus		0.0065	0.0031	0.0138
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Mycobacterium leprae	probable zinc metalloprotease	0.0291	0.0374	1
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0065	0.0031	0.0031
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0899	0.1293	0.1283
Brugia malayi	Histone deacetylase family protein	0.0693	0.0981	0.0971
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Brugia malayi	Protein kinase domain containing protein	0.0065	0.0031	0.002
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0053	0.0013	0.0013
Schistosoma mansoni	histone deacetylase	0.0796	0.1137	0.1137
Loa Loa (eye worm)	hypothetical protein	0.0291	0.0374	0.0364
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.3627	0.5418	0.5418
Schistosoma mansoni	protein kinase	0.0056	0.0018	0.0018
Brugia malayi	Cytochrome P450 family protein	0.0059	0.0022	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0134	0.0136	0.0126
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Loa Loa (eye worm)	TK/INSR protein kinase	0.2135	0.3163	0.3156
Schistosoma mansoni	hypothetical protein	0.0076	0.0048	0.0048
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit gamma, putative	0.2969	0.4424	1
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0053	0.0013	0.0013
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0053	0.0013	0.0013
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0103	0.0089	0.0089
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Plasmodium falciparum	protein kinase, putative	0.0056	0.0018	0.0156
Loa Loa (eye worm)	TK/ACK protein kinase	0.0053	0.0013	0.0002
Echinococcus granulosus	phosphatidylinositol 4 kinase alpha	0.0591	0.0826	0.0826
Entamoeba histolytica	phosphatidylinositol3-kinaseTor2, putative	0.0134	0.0136	0.0307
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Loa Loa (eye worm)	phosphatidylinositol 3	0.0765	0.109	0.108
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Leishmania major	phosphatidylinositol 3-kinase, putative	0.0591	0.0826	0.202
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0053	0.0013	0.0013
Toxoplasma gondii	histone deacetylase HDAC2	0.0796	0.1137	0.2779
Trichomonas vaginalis	histone deacetylase 1, 2 ,3, putative	0.0796	0.1137	0.2549
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0065	0.0031	0.0071
Echinococcus multilocularis	phosphatidylinositol 4 kinase alpha	0.0591	0.0826	0.0826
Echinococcus multilocularis	tyrosine protein kinase	0.0053	0.0013	0.0013
Plasmodium vivax	hypothetical protein, conserved	0.0134	0.0136	0.1196
Loa Loa (eye worm)	TK/FER protein kinase	0.0065	0.0031	0.0021
Loa Loa (eye worm)	TK/FER protein kinase	0.0065	0.0031	0.0021
Echinococcus multilocularis	tyrosine protein kinase csk	0.0053	0.0013	0.0013
Entamoeba histolytica	protein kinase domain containing protein	0.0056	0.0018	0.004
Echinococcus multilocularis	tyrosine kinase	0.0065	0.0031	0.0031
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0053	0.0013	0.0002
Entamoeba histolytica	hypothetical protein	0.0134	0.0136	0.0307
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0053	0.0013	0.0112
Leishmania major	histone deacetylase, putative	0.0693	0.0981	0.2399
Brugia malayi	ephrin receptor 1 precursor	0.0152	0.0162	0.0151
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0053	0.0013	0.0013
Brugia malayi	hypothetical protein	0.0065	0.0031	0.002
Echinococcus granulosus	phosphatidylinositol 45 bisphosphate 3 kinase	0.4299	0.6435	0.6435
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Toxoplasma gondii	phosphatidylinositol 3- and 4-kinase	0.0134	0.0136	0.0332
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0036	0.0026
Loa Loa (eye worm)	TK/FER protein kinase	0.0065	0.0031	0.0021
Loa Loa (eye worm)	TK/FER protein kinase	0.0065	0.0031	0.0021
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Loa Loa (eye worm)	peptidase family M13 containing protein	0.0215	0.0259	0.0249
Echinococcus granulosus	tm gpcr rhodopsin	0.0512	0.0707	0.0707
Loa Loa (eye worm)	hypothetical protein	0.0112	0.0103	0.0092
Toxoplasma gondii	peptidase family M13 protein	0.0291	0.0374	0.0914
Schistosoma mansoni	fructose-16-bisphosphatase-related	0.2749	0.4091	0.4091
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0134	0.0136	0.0125
Schistosoma mansoni	protein kinase	0.0056	0.0018	0.0018
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0084	0.0059	0.0059
Brugia malayi	peptidase family M13 containing protein	0.0071	0.004	0.0029
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0156	0.0168	0.0168
Trypanosoma brucei	phosphatidylinositol 3-kinase catalytic subunit, putative	0.0134	0.0136	0.0332
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Schistosoma mansoni	phosphatidylinositol 3-kinase class	0.0134	0.0136	0.0136
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0053	0.0013	0.0002
Entamoeba histolytica	serine/threonine kinase, putative	0.0053	0.0013	0.0029
Plasmodium vivax	histone deacetylase 2, putative	0.0693	0.0981	0.8632
Loa Loa (eye worm)	hypothetical protein	0.0337	0.0442	0.0432
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Schistosoma mansoni	histone deacetylase hda2	0.0337	0.0442	0.0442
Echinococcus multilocularis	Immunoglobulin	0.0068	0.0036	0.0036
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0147	0.0155	0.0155
Trypanosoma brucei	dihydrofolate reductase-thymidylate synthase	0.0113	0.0103	0.0253
Mycobacterium ulcerans	zinc metalloprotease	0.0291	0.0374	1
Plasmodium falciparum	tyrosine kinase-like protein	0.0053	0.0013	0.0112
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0096	0.0078	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0215	0.0259	0.0249
Loa Loa (eye worm)	hypothetical protein	0.022	0.0266	0.0256
Toxoplasma gondii	histone deacetylase HDAC4	0.0337	0.0442	0.108
Entamoeba histolytica	hypothetical protein	0.0134	0.0136	0.0307
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Loa Loa (eye worm)	fructose-1,6-bisphosphatase	0.2749	0.4091	0.4085
Trichomonas vaginalis	phosphatidylinositol 4-kinase, putative	0.0591	0.0826	0.1844
Giardia lamblia	Kinase, CMGC MAPK	0.0057	0.0019	0.0019
Toxoplasma gondii	CMGC kinase, MAPK family (ERK) MAPK-1	0.0057	0.0019	0.0046
Trypanosoma cruzi	dihydrofolate reductase-thymidylate synthase	0.0113	0.0103	0.0234
Trichomonas vaginalis	histone deacetylase 1, 2 ,3, putative	0.0796	0.1137	0.2549
Schistosoma mansoni	histone deacetylase	0.0796	0.1137	0.1137
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Schistosoma mansoni	peptidylglycine monooxygenase	0.0122	0.0118	0.0118
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0134	0.0136	0.0125
Schistosoma mansoni	tyrosine kinase	0.0271	0.0343	0.0343
Leishmania major	target of rapamycin (TOR) kinase 1, putative	0.0134	0.0136	0.0332
Trypanosoma cruzi	mitogen activated protein kinase 2, putative	0.0057	0.0019	0.0043
Echinococcus multilocularis	roundabout 2	0.0052	0.0011	0.0011
Echinococcus multilocularis	Phosphatidylinositol 4 kinase type 2 beta	0.0134	0.0136	0.0136
Loa Loa (eye worm)	phosphatidylinositol 3	0.0134	0.0136	0.0126
Echinococcus multilocularis	histone deacetylase 6	0.0693	0.0981	0.0981
Trypanosoma brucei	phosphatidylinositol 4-kinase, putative	0.0134	0.0136	0.0332
Trypanosoma brucei	phosphatidylinositol 3-kinase tor, putative	0.0134	0.0136	0.0332
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.1372	0.2008	0.1999
Loa Loa (eye worm)	TK/FER protein kinase	0.0065	0.0031	0.0021
Brugia malayi	Raf kinase	0.0053	0.0013	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0013	0.0002
Schistosoma mansoni	neprilysin	0.0076	0.0048	0.0048
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.2969	0.4424	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Brugia malayi	Tyrosine-protein kinase PR2	0.0053	0.0013	0.0001
Loa Loa (eye worm)	TK/CSK protein kinase	0.0053	0.0013	0.0002
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0134	0.0136	0.0125
Trichomonas vaginalis	conserved hypothetical protein	0.0134	0.0136	0.0279
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Entamoeba histolytica	tyrosin kinase, putative	0.0053	0.0013	0.0029
Entamoeba histolytica	hypothetical protein	0.0053	0.0013	0.0029
Trichomonas vaginalis	histone deacetylase, putative	0.0796	0.1137	0.2549
Leishmania major	phosphatidylinositol 3-related kinase, putative	0.0134	0.0136	0.0332
Echinococcus granulosus	Phosphatidylinositol 4 kinase type 2 beta	0.0134	0.0136	0.0136
Echinococcus granulosus	tyrosine protein kinase shark	0.0065	0.0031	0.0031
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0134	0.0136	0.0125
Echinococcus granulosus	tyrosine kinase	0.0053	0.0013	0.0013
Leishmania major	hypothetical protein, conserved	0.0134	0.0136	0.0332
Schistosoma mansoni	tyrosine kinase	0.2135	0.3163	0.3163
Toxoplasma gondii	STE kinase	0.0053	0.0013	0.0031
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0053	0.0013	0.0013
Loa Loa (eye worm)	cytochrome P450 family protein	0.0059	0.0022	0.0012
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0134	0.0136	0.0279
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Loa Loa (eye worm)	hypothetical protein	0.0134	0.0136	0.0126
Schistosoma mansoni	bifunctional dihydrofolate reductase-thymidylate synthase	0.008	0.0054	0.0054
Entamoeba histolytica	serine/threonine kinase, putative	0.0053	0.0013	0.0029
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0053	0.0013	0.0013
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Onchocerca volvulus		0.0065	0.0031	0.0138
Echinococcus multilocularis	protein tyrosine kinase	0.0053	0.0013	0.0013
Brugia malayi	Protein kinase domain containing protein	0.2135	0.3163	0.3155
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Brugia malayi	fructose-1,6-bisphosphatase	0.2749	0.4091	0.4085
Schistosoma mansoni	cell adhesion molecule	0.0098	0.0082	0.0082
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0103	0.0089	0.0089
Echinococcus multilocularis	contactin neuroglian septate junction protein	0.0052	0.0011	0.0011
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.0591	0.0826	0.0826
Echinococcus granulosus	roundabout 2	0.012	0.0115	0.0115
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0053	0.0013	0.0013
Trichomonas vaginalis	phopsphatidylinositol 3-kinase, drosophila, putative	0.0134	0.0136	0.0279
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0053	0.0013	0.0013
Echinococcus multilocularis	serine protein kinase ATM	0.0134	0.0136	0.0136
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Brugia malayi	Immunoglobulin I-set domain containing protein	0.101	0.146	0.145
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Loa Loa (eye worm)	phosphatidylinositol 3	0.3991	0.5968	0.5964
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0013	0.0002
Trypanosoma brucei	mitogen activated protein kinase 4, putative	0.0057	0.0019	0.0046
Brugia malayi	Protein kinase domain containing protein	0.0065	0.0031	0.002
Loa Loa (eye worm)	hypothetical protein	0.022	0.0266	0.0256
Schistosoma mansoni	serine/threonine protein kinase	0.0053	0.0013	0.0013
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0899	0.1293	0.2902
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0103	0.0089	0.0089
Echinococcus multilocularis	receptor type tyrosine protein phosphatase F	0.0052	0.0011	0.0011
Trypanosoma cruzi	histone deacetylase 1, putative	0.0796	0.1137	0.257
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0053	0.0013	0.0002
Echinococcus multilocularis	activated cdc42 kinase 1	0.0053	0.0013	0.0013
Echinococcus granulosus	tyrosine protein kinase csk	0.0053	0.0013	0.0013
Schistosoma mansoni	tyrosine kinase	0.2135	0.3163	0.3163
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0071	0.004	0.004
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0053	0.0013	0.0029
Brugia malayi	histone deacetylase 1 (HD1)	0.0796	0.1137	0.1127
Schistosoma mansoni	defective proboscis extension response (dpr)-related	0.0068	0.0036	0.0036
Echinococcus granulosus	mitogen activated protein kinase	0.0057	0.0019	0.0019
Loa Loa (eye worm)	TK/FER protein kinase	0.0053	0.0013	0.0002
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0053	0.0013	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0013	0.0002
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0053	0.0013	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0036	0.0026
Schistosoma mansoni	phosphatidylinositol 3-and 4-kinase	0.0134	0.0136	0.0136
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.0899	0.1293	0.1293
Loa Loa (eye worm)	hypothetical protein	0.022	0.0266	0.0256
Schistosoma mansoni	histone deacetylase 4 5	0.0693	0.0981	0.0981
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Echinococcus granulosus	integrin linked protein kinase	0.0053	0.0013	0.0013
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0053	0.0013	0.0029
Mycobacterium leprae	conserved hypothetical protein	0.0134	0.0136	0.2563
Leishmania major	protein kinase, putative	0.0053	0.0013	0.0031
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0053	0.0013	0.0002
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Brugia malayi	Hypothetical zinc metalloproteinase T16A9.4	0.0291	0.0374	0.0363
Entamoeba histolytica	FKBP-rapamycin associated protein (FRAP), putative	0.0134	0.0136	0.0307
Loa Loa (eye worm)	hypothetical protein	0.0291	0.0374	0.0364
Schistosoma mansoni	histone deacetylase hda2	0.0709	0.1005	0.1005
Leishmania major	histone deacetylase, putative	0.0796	0.1137	0.2779
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0591	0.0826	0.1844
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0056	0.0018	0.004
Plasmodium falciparum	bifunctional dihydrofolate reductase-thymidylate synthase	0.0113	0.0103	0.091
Echinococcus multilocularis	histone deacetylase 6	0.0693	0.0981	0.0981
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0053	0.0013	0.0029
Brugia malayi	Peptidase family M13 containing protein	0.0291	0.0374	0.0363
Loa Loa (eye worm)	SRC-1	0.0103	0.0089	0.0078
Echinococcus multilocularis	phosphatidylinositol 4 phosphate 3 kinase C2	0.1372	0.2008	0.2008
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0053	0.0013	0.0013
Echinococcus granulosus	histone deacetylase 1	0.0796	0.1137	0.1137
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Entamoeba histolytica	hypothetical protein	0.0053	0.0013	0.0029
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Loa Loa (eye worm)	hypothetical protein	0.021	0.025	0.024
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.2661	0.3957	0.8946
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0048	0.0038
Schistosoma mansoni	serine/threonine protein kinase	0.0053	0.0013	0.0013
Schistosoma mansoni	endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase)	0.0071	0.004	0.004
Schistosoma mansoni	ephrin receptor	0.0263	0.033	0.033
Loa Loa (eye worm)	TK protein kinase	0.0074	0.0045	0.0035
Loa Loa (eye worm)	TK/DDR protein kinase	0.0053	0.0013	0.0002
Brugia malayi	hypothetical protein	0.0076	0.0048	0.0037
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0053	0.0013	0.0013
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Trypanosoma cruzi	fructose-1,6-bisphosphatase, cytosolic, putative	0.2749	0.4091	0.9248
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0052	0.0011	0.0011
Trypanosoma cruzi	phosphatidylinositol 4-kinase, putative	0.0134	0.0136	0.0307
Echinococcus granulosus	phosphatidylinositol 3 kinase catalytic subunit	0.0591	0.0826	0.0826
Schistosoma mansoni	serine/threonine RGC	0.0053	0.0013	0.0013
Trypanosoma cruzi	histone deacetylase, putative	0.0337	0.0442	0.0999
Loa Loa (eye worm)	TK/FER protein kinase	0.0065	0.0031	0.0021
Echinococcus multilocularis		0.212	0.3139	0.3139
Loa Loa (eye worm)	hypothetical protein	0.0291	0.0374	0.0364
Entamoeba histolytica	ankyrin repeat protein	0.0053	0.0013	0.0029
Echinococcus granulosus	histone deacetylase 8	0.0337	0.0442	0.0442
Trypanosoma cruzi	phosphatidylinositol 4-kinase alpha, putative	0.0591	0.0826	0.1868
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0103	0.0089	0.0089
Echinococcus granulosus	natriuretic peptide receptor 1	0.0053	0.0013	0.0013
Leishmania major	target of rapamycin kinase (TOR) kinase 3	0.0134	0.0136	0.0332
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0053	0.0013	0.0002
Schistosoma mansoni	phosphatidylinositol 4-kinase	0.0134	0.0136	0.0136
Echinococcus multilocularis	Immunoglobulin	0.0068	0.0036	0.0036
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0053	0.0013	0.0013
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Echinococcus granulosus	tyrosyl DNA phosphodiesterase 1	0.007	0.0039	0.0039
Schistosoma mansoni	endothelin-converting enzyme-related	0.0071	0.004	0.004
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative	0.2496	0.3709	0.8379
Trypanosoma brucei	phosphatidylinositol 3-related kinase, putative	0.0134	0.0136	0.0332
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Entamoeba histolytica	hypothetical protein	0.0053	0.0013	0.0029
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0071	0.004	0.004
Onchocerca volvulus		0.0144	0.0151	0.1032
Brugia malayi	Receptor family ligand binding region containing protein	0.0053	0.0013	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0134	0.0136	0.0126
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Entamoeba histolytica	protein kinase with ankyrin repeats, putative	0.0053	0.0013	0.0029
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Trypanosoma brucei	histone deacetylase 3	0.0693	0.0981	0.2399
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0134	0.0136	0.0307
Leishmania major	hypothetical protein, conserved	0.0053	0.0013	0.0031
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0013	0.0002
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0071	0.004	0.004
Echinococcus granulosus	c src tyrosine kinase	0.0072	0.0042	0.0042
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0103	0.0089	0.0089
Entamoeba histolytica	Phosphatidylinositol 3- and 4-kinase family	0.0134	0.0136	0.0307
Echinococcus multilocularis	peptidyl glycine alpha amidating monooxygenase	0.023	0.0281	0.0281
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0134	0.0136	0.0125
Schistosoma mansoni	hypothetical protein	0.0134	0.0136	0.0136
Entamoeba histolytica	hypothetical protein, conserved	0.0053	0.0013	0.0029
Schistosoma mansoni	jumonji domain containing protein	0.0078	0.005	0.005
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0053	0.0013	0.0029
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0053	0.0013	0.0013
Trypanosoma brucei	phosphatidylinositol kinase related protein, putative	0.0134	0.0136	0.0332
Echinococcus multilocularis	mitogen activated protein kinase 14	0.0402	0.0541	0.0541
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0053	0.0013	0.0013
Brugia malayi	histone deacetylase 3 (HD3)	0.0796	0.1137	0.1127
Loa Loa (eye worm)	phosphatidylinositol 3	0.0134	0.0136	0.0126
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0076	0.0048	0.0048
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.0057	0.0019	0.0043
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Schistosoma mansoni	fkbp-rapamycin associated protein	0.0134	0.0136	0.0136
Entamoeba histolytica	hypothetical protein	0.2661	0.3957	0.8946
Loa Loa (eye worm)	hypothetical protein	0.0107	0.0095	0.0084
Schistosoma mansoni	serine/threonine protein kinase	0.0053	0.0013	0.0013
Leishmania major	target of rapamycin (TOR) kinase 2, putative	0.0134	0.0136	0.0332
Echinococcus multilocularis	roundabout 2	0.0052	0.0011	0.0011
Trypanosoma brucei	phosphatidylinositol 3-kinase, putative	0.0899	0.1293	0.316
Echinococcus multilocularis	mitogen activated protein kinase 3	0.0057	0.0019	0.0019
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0103	0.0089	0.0089
Brugia malayi	Protein kinase domain containing protein	0.0065	0.0031	0.002
Loa Loa (eye worm)	TK/EPH protein kinase	0.032	0.0417	0.0407
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0053	0.0013	0.0031
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0013	0.0002
Trypanosoma cruzi	mitogen-activated protein kinase 3, putative	0.0402	0.0541	0.1224
Loa Loa (eye worm)	hypothetical protein	0.0372	0.0496	0.0486
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0103	0.0089	0.0089
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0053	0.0013	0.0001
Loa Loa (eye worm)	histone deacetylase 11	0.0337	0.0442	0.0432
Onchocerca volvulus		0.0065	0.0031	0.0138
Loa Loa (eye worm)	TK/ROR protein kinase	0.0074	0.0045	0.0035
Schistosoma mansoni	tyrosine kinase	0.3574	0.5338	0.5338
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0053	0.0013	0.0013
Schistosoma mansoni	leukotriene A4 hydrolase (M01 family)	0.0239	0.0294	0.0294
Schistosoma mansoni	phosphatidylinositol 4-kinase	0.0591	0.0826	0.0826
Echinococcus granulosus	raf serine:threonine protein kinase	0.0053	0.0013	0.0013
Brugia malayi	SH2 domain containing protein	0.0065	0.0031	0.002
Echinococcus multilocularis		0.0134	0.0136	0.0136
Echinococcus multilocularis	phosphatidylinositol 3 and 4 kinase	0.0134	0.0136	0.0136
Schistosoma mansoni	microtubule-associated protein tau	0.0731	0.1039	0.1039
Schistosoma mansoni	Neurotrimin precursor (hNT)	0.0068	0.0036	0.0036
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0053	0.0013	0.0013
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0053	0.0013	0.0029
Onchocerca volvulus		0.0065	0.0031	0.0138
Loa Loa (eye worm)	TK protein kinase	0.0053	0.0013	0.0002
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.2496	0.3709	0.8379
Loa Loa (eye worm)	hypothetical protein	0.1597	0.2349	0.2341
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Entamoeba histolytica	tyrosin kinase, putative	0.0053	0.0013	0.0029
Entamoeba histolytica	hypothetical protein	0.0053	0.0013	0.0029
Entamoeba histolytica	serine/threonine kinase, putative	0.0053	0.0013	0.0029
Onchocerca volvulus	Tyrosine kinase homolog	0.0941	0.1356	1
Giardia lamblia	GTOR	0.0134	0.0136	0.0382
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0053	0.0013	0.0002
Echinococcus multilocularis	tyrosine protein kinase csk	0.0053	0.0013	0.0013
Loa Loa (eye worm)	TK/FER protein kinase	0.0065	0.0031	0.0021
Brugia malayi	Histone deacetylase family protein	0.0693	0.0981	0.0971
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Echinococcus multilocularis	fructose 1,6 bisphosphatase 1	0.2749	0.4091	0.4091
Brugia malayi	Histone deacetylase 1	0.0796	0.1137	0.1127
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0103	0.0089	0.0089
Plasmodium vivax	hypothetical protein	0.0134	0.0136	0.1196
Entamoeba histolytica	hypothetical protein	0.0053	0.0013	0.0029
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0134	0.0136	0.0125
Schistosoma mansoni	peptidyl-glycine monooxygenase	0.023	0.0281	0.0281
Echinococcus granulosus	tyrosine protein kinase Blk	0.0096	0.0078	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Echinococcus granulosus	tyrosine protein kinase Srms	0.0065	0.0031	0.0031
Entamoeba histolytica	hypothetical protein	0.0053	0.0013	0.0029
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Loa Loa (eye worm)	TK/FAK protein kinase	0.0053	0.0013	0.0002
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0899	0.1293	0.2922
Onchocerca volvulus	Histone deacetylase 10 homolog	0.0337	0.0442	0.3197
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Loa Loa (eye worm)	jmjC domain-containing protein	0.0062	0.0026	0.0016
Onchocerca volvulus		0.0134	0.0136	0.0918
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0056	0.0018	0.0043
Entamoeba histolytica	phosphatidylinositol 3-kinase 3, putative	0.0134	0.0136	0.0307
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Schistosoma mansoni	tyrosine kinase	0.3574	0.5338	0.5338
Schistosoma mansoni	hypothetical protein	0.0053	0.0013	0.0013
Trypanosoma cruzi	phosphatidylinositol 3-kinase, putative	0.0765	0.109	0.2463
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0103	0.0089	0.0089
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.0091	0.007	0.007
Echinococcus multilocularis	integrin linked protein kinase	0.0053	0.0013	0.0013
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0053	0.0013	0.0013
Onchocerca volvulus		0.008	0.0054	0.0308
Toxoplasma gondii	phosphatidylinositol 3- and 4-kinase	0.0591	0.0826	0.202
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Echinococcus multilocularis	thymidylate synthase	0.008	0.0054	0.0054
Entamoeba histolytica	hypothetical protein	0.0053	0.0013	0.0029
Leishmania major	phosphatidylinositol 4-kinase alpha, putative	0.0591	0.0826	0.202
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0053	0.0013	0.0031
Echinococcus multilocularis	FL cytokine receptor	0.0053	0.0013	0.0013
Schistosoma mansoni	tyrosyl-DNA phosphodiesterase	0.007	0.0039	0.0039
Plasmodium vivax	phosphatidylinositol 4-kinase, putative	0.0134	0.0136	0.1196
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0096	0.0078	0.0078
Entamoeba histolytica	cysteine surface protein, putative	0.0053	0.0013	0.0029
Loa Loa (eye worm)	TK protein kinase	0.0053	0.0013	0.0002
Trichomonas vaginalis	CMGC family protein kinase	0.0057	0.0019	0.0014
Onchocerca volvulus		0.0065	0.0031	0.0138
Trypanosoma brucei	target of rapamycin kinase 3, putative	0.0134	0.0136	0.0332
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0056	0.0018	0.0018
Loa Loa (eye worm)	TK/FER protein kinase	0.0065	0.0031	0.0021
Echinococcus multilocularis	activin receptor type	0.0056	0.0018	0.0018
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Echinococcus granulosus	roundabout 2	0.0052	0.0011	0.0011
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0074	0.0045	0.0034
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0053	0.0013	0.0013
Echinococcus multilocularis	histone deacetylase 8	0.0337	0.0442	0.0442
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0147	0.0155	0.0155
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0072	0.0042	0.0042
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0052	0.0011	0.0011
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.0899	0.1293	0.2902
Leishmania major	phosphatidylinositol 3-kinase, putative	0.0134	0.0136	0.0332
Entamoeba histolytica	tyrosine- protein kinase 2, putative	0.0053	0.0013	0.0029
Loa Loa (eye worm)	phosphatidylinositol 3	0.0134	0.0136	0.0126
Leishmania major	mitogen activated protein kinase, putative,map kinase, putative	0.0057	0.0019	0.0046
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Loa Loa (eye worm)	TK/FER protein kinase	0.0053	0.0013	0.0002
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0103	0.0089	0.0089
Trypanosoma cruzi	sedoheptulose-1,7-bisphosphatase, putative	0.1022	0.1479	0.3344
Brugia malayi	SH2 domain containing protein	0.0065	0.0031	0.002
Loa Loa (eye worm)	hypothetical protein	0.022	0.0266	0.0256
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0899	0.1293	0.2922
Onchocerca volvulus		0.0866	0.1243	0.9163
Entamoeba histolytica	serine/threonine kinase, putative	0.0053	0.0013	0.0029
Plasmodium falciparum	protein kinase, putative	0.0053	0.0013	0.0112
Trypanosoma brucei	phosphatidylinositol 3-kinase, putative	0.0134	0.0136	0.0332
Loa Loa (eye worm)	hypothetical protein	0.022	0.0266	0.0256
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0053	0.0013	0.0013
Leishmania major	phosphatidylinositol 4-kinase, putative	0.0134	0.0136	0.0332
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0103	0.0089	0.0089
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0134	0.0136	0.0125
Loa Loa (eye worm)	serine/threonine protein kinase	0.0053	0.0013	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0048	0.0038
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0098	0.0081	0.0081
Trypanosoma cruzi	histone deacetylase, putative	0.0693	0.0981	0.2218
Brugia malayi	hypothetical protein	0.0053	0.0013	0.0001
Brugia malayi	Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein	0.023	0.0281	0.027
Trypanosoma cruzi	target of rapamycin kinase 3	0.0134	0.0136	0.0307
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0053	0.0013	0.0031
Echinococcus granulosus	Phosphatidylinositol 4 kinase type 2 beta	0.0134	0.0136	0.0136
Leishmania major	histone deacetylase, putative	0.0693	0.0981	0.2399
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Echinococcus granulosus	tyrosine protein kinase csk	0.0053	0.0013	0.0013
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0103	0.0089	0.0089
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.0057	0.0019	0.0043
Trichomonas vaginalis	CMGC family protein kinase	0.0057	0.0019	0.0014
Trypanosoma brucei	histone deacetylase 2	0.0337	0.0442	0.108
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0053	0.0013	0.0029
Loa Loa (eye worm)	TK/EGFR protein kinase	0.6656	1	1
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0011	0.0001
Plasmodium vivax	protein kinase, putative	0.0069	0.0038	0.0331
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0053	0.0013	0.0001
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0106	0.0094	0.0094
Echinococcus granulosus	protein tyrosine kinase	0.0053	0.0013	0.0013
Brugia malayi	thymidylate synthase	0.008	0.0054	0.0043
Loa Loa (eye worm)	histone deacetylase	0.0693	0.0981	0.0972
Loa Loa (eye worm)	CMGC/MAPK/P38 protein kinase	0.0402	0.0541	0.0532
Trypanosoma cruzi	phosphatidylinositol 3-kinase, putative	0.0134	0.0136	0.0307
Schistosoma mansoni	protein kinase	0.0053	0.0013	0.0013
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Plasmodium falciparum	tyrosine kinase-like protein	0.0053	0.0013	0.0112
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Trypanosoma cruzi	sedoheptulose-1,7-bisphosphatase, putative	0.1022	0.1479	0.3344
Loa Loa (eye worm)	camk/mapkapk/mnk protein kinase	0.0788	0.1125	0.1116
Loa Loa (eye worm)	TK protein kinase	0.0053	0.0013	0.0002
Echinococcus granulosus	FKBP12 rapamycin complex associated protein	0.0134	0.0136	0.0136
Echinococcus multilocularis	Phosphatidylinositol 4 kinase type 2 beta	0.0134	0.0136	0.0136
Entamoeba histolytica	receptor protein kinase, putative	0.0053	0.0013	0.0029
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Schistosoma mansoni	tyrosine protein kinase	0.0053	0.0013	0.0013
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0053	0.0013	0.0013
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0053	0.0013	0.0013
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.0591	0.0826	0.1844
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0291	0.0374	0.0374
Schistosoma mansoni	tyrosine kinase	0.3627	0.5418	0.5418
Trypanosoma cruzi	phosphatidylinositol 4-kinase, putative	0.0134	0.0136	0.0307
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0134	0.0136	0.0307
Brugia malayi	Protein kinase domain containing protein	0.0788	0.1125	0.1115
Loa Loa (eye worm)	TK protein kinase	0.0096	0.0078	0.0068
Echinococcus multilocularis	FKBP12 rapamycin complex associated protein	0.0134	0.0136	0.0136
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Schistosoma mansoni	serine/threonine protein kinase	0.006	0.0023	0.0023
Trypanosoma brucei	phosphatidylinositol 4-kinase alpha, putative	0.0591	0.0826	0.202
Schistosoma mansoni	tyrosine kinase	0.3574	0.5338	0.5338
Brugia malayi	Protein kinase domain containing protein	0.0065	0.0031	0.002
Echinococcus granulosus	tyrosine protein kinase	0.0053	0.0013	0.0013
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Echinococcus multilocularis	Zinc finger, PHD finger	0.0591	0.0826	0.0826
Giardia lamblia	Phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.2188	0.3242	1
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0053	0.0013	0.0002
Trichomonas vaginalis	histone deacetylase, putative	0.0796	0.1137	0.2549
Echinococcus multilocularis	mitogen activated protein kinase 11	0.0402	0.0541	0.0541
Brugia malayi	P38 map kinase family protein 2	0.0402	0.0541	0.0531
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Echinococcus multilocularis	tyrosine protein kinase csk	0.0053	0.0013	0.0013
Trypanosoma brucei	fructose-1,6-bisphosphatase	0.2749	0.4091	1
Brugia malayi	SRC-1	0.0103	0.0089	0.0077
Loa Loa (eye worm)	hypothetical protein	0.0215	0.0259	0.0249
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Brugia malayi	histone deacetylase 11	0.0337	0.0442	0.0431
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0072	0.0042	0.0042
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Schistosoma mansoni	family M13 non-peptidase homologue (M13 family)	0.0071	0.004	0.004
Trichomonas vaginalis	histone deacetylase 1, 2 ,3, putative	0.0796	0.1137	0.2549
Loa Loa (eye worm)	TK/FER protein kinase	0.0065	0.0031	0.0021
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0053	0.0013	0.0013
Echinococcus granulosus	activin receptor type	0.0056	0.0018	0.0018
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0053	0.0013	0.0013
Brugia malayi	Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein	0.0122	0.0118	0.0107
Echinococcus granulosus	mitogen activated protein kinase 11	0.0402	0.0541	0.0541
Schistosoma mansoni	hypothetical protein	0.0076	0.0048	0.0048
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0053	0.0013	0.0029
Echinococcus multilocularis	histone deacetylase 1	0.0796	0.1137	0.1137
Echinococcus granulosus	epidermal growth factor receptor	0.6656	1	1
Loa Loa (eye worm)	phosphatidylinositol 3	0.0134	0.0136	0.0126
Echinococcus granulosus	mitogen activated protein kinase 14	0.0402	0.0541	0.0541
Echinococcus multilocularis	epidermal growth factor receptor	0.3627	0.5418	0.5418
Echinococcus multilocularis	histone deacetylase 3	0.0796	0.1137	0.1137
Echinococcus granulosus	epidermal growth factor receptor	0.3627	0.5418	0.5418
Echinococcus multilocularis	transfer RNA-Thr	0.0053	0.0013	0.0013
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0103	0.0089	0.0089
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Plasmodium falciparum	histone deacetylase 2	0.0693	0.0981	0.8632
Echinococcus granulosus	receptor type guanylyl cyclase	0.0053	0.0013	0.0013
Entamoeba histolytica	ankyrin repeat protein	0.0053	0.0013	0.0029
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0053	0.0013	0.0029
Schistosoma mansoni	phosphatidylinositol 4-kinase type-II	0.0134	0.0136	0.0136
Plasmodium falciparum	histone deacetylase, putative	0.0693	0.0981	0.8632
Schistosoma mansoni	protein kinase	0.0053	0.0013	0.0013
Trypanosoma brucei	histone deacetylase 4	0.0693	0.0981	0.2399
Loa Loa (eye worm)	hypothetical protein	0.0796	0.1137	0.1128
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0074	0.0045	0.0045
Toxoplasma gondii	histone deacetylase HDAC5	0.0337	0.0442	0.108
Brugia malayi	jmjC domain containing protein	0.0098	0.0081	0.0069
Plasmodium vivax	histone deacetylase, putative	0.0337	0.0442	0.3888
Entamoeba histolytica	tyrosin kinase, putative	0.0053	0.0013	0.0029
Entamoeba histolytica	histone deacetylase, putative	0.0796	0.1137	0.257
Trypanosoma cruzi	phosphatidylinositol 4-kinase alpha, putative	0.0591	0.0826	0.1868
Echinococcus granulosus	histone deacetylase 6	0.0693	0.0981	0.0981
Echinococcus granulosus	microtubule associated protein 2	0.0731	0.1039	0.1039
Entamoeba histolytica	protein kinase rad3, putative	0.0134	0.0136	0.0307
Echinococcus multilocularis	mitogen activated protein kinase	0.0057	0.0019	0.0019
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0053	0.0013	0.0013
Trypanosoma cruzi	phosphatidylinositol 3-kinase 2, putative	0.2969	0.4424	1
Entamoeba histolytica	phosphatidylinositol 4-kinase, putative	0.0591	0.0826	0.1868
Trypanosoma brucei	sedoheptulose-1,7-bisphosphatase	0.1022	0.1479	0.3616
Loa Loa (eye worm)	hypothetical protein	0.022	0.0266	0.0256
Echinococcus multilocularis	tyrosyl DNA phosphodiesterase 1	0.007	0.0039	0.0039
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0053	0.0013	0.0013
Loa Loa (eye worm)	hypothetical protein	0.1372	0.2008	0.1999
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Giardia lamblia	Phosphoinositide-3-kinase, class 3	0.0443	0.0602	0.1826
Leishmania major	mitogen-activated protein kinase 3, putative,map kinase 3, putative	0.0402	0.0541	0.1323
Schistosoma mansoni	protein kinase	0.0053	0.0013	0.0013
Trypanosoma brucei	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.007	0.0039	0.0095
Toxoplasma gondii	phosphatidylinositol 3- and 4-kinase	0.0591	0.0826	0.202
Echinococcus multilocularis	serine:threonine protein kinase SMG1	0.0134	0.0136	0.0136
Trypanosoma cruzi	phosphatidylinositol 3-related kinase, putative	0.0134	0.0136	0.0307
Entamoeba histolytica	receptor protein kinase, putative	0.0053	0.0013	0.0029
Trichomonas vaginalis	histone deacetylase, putative	0.0796	0.1137	0.2549
Entamoeba histolytica	protein kinase, putative	0.0084	0.0059	0.0134
Echinococcus granulosus	phosphatidylinositol 4 phosphate 3 kinase C2	0.1372	0.2008	0.2008
Echinococcus granulosus	serine protein kinase ATM	0.0134	0.0136	0.0136
Brugia malayi	protein-tyrosine kinase	0.0096	0.0078	0.0067
Trypanosoma cruzi	protein kinase, putative	0.0053	0.0013	0.0029
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0052	0.0011	0.0011
Loa Loa (eye worm)	TK/FER protein kinase	0.0065	0.0031	0.0021
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0103	0.0089	0.0089
Echinococcus granulosus	contactin	0.0052	0.0011	0.0011
Trypanosoma cruzi	mitogen-activated protein kinase 3, putative	0.0402	0.0541	0.1224
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0053	0.0013	0.0013
Brugia malayi	phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative	0.133	0.1944	0.1935
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0053	0.0013	0.0029
Toxoplasma gondii	protein kinase domain-containing protein	0.0053	0.0013	0.0031
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0053	0.0013	0.0031
Schistosoma mansoni	tyrosine kinase	0.0065	0.0031	0.0031
Loa Loa (eye worm)	TK protein kinase	0.0053	0.0013	0.0002
Leishmania major	mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440	0.0057	0.0019	0.0046
Brugia malayi	phosphatidylinositol 4-kinase, catalytic, alpha polypeptide	0.0591	0.0826	0.0816
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0053	0.0013	0.0001
Entamoeba histolytica	hypothetical protein	0.0053	0.0013	0.0029
Echinococcus granulosus	neuroglian	0.009	0.0069	0.0069
Echinococcus granulosus	phosphatidylinositol 3 and 4 kinase	0.0134	0.0136	0.0136
Trypanosoma brucei	histone deacetylase 1	0.0796	0.1137	0.2779
Loa Loa (eye worm)	leukotriene A4 hydrolase	0.0239	0.0294	0.0284
Toxoplasma gondii	non-specific serine/threonine protein kinase	0.0134	0.0136	0.0332
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Trypanosoma cruzi	phosphatidylinositol 3-related kinase, putative	0.0134	0.0136	0.0307
Entamoeba histolytica	hypothetical protein	0.0053	0.0013	0.0029
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0056	0.0018	0.0018
Entamoeba histolytica	tyrosine kinase, putative	0.0053	0.0013	0.0029
Brugia malayi	Guanylyl cyclase protein 23	0.0053	0.0013	0.0001
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Echinococcus granulosus	tyrosine kinase	0.0096	0.0078	0.0078
Loa Loa (eye worm)	histone deacetylase 1	0.0796	0.1137	0.1128
Plasmodium falciparum	phosphatidylinositol 3-kinase	0.0591	0.0826	0.7268
Schistosoma mansoni	tyrosine kinase	0.0072	0.0042	0.0042
Echinococcus granulosus	roundabout 2	0.0052	0.0011	0.0011
Brugia malayi	Tyrosine-protein kinase abl-1	0.0156	0.0168	0.0157
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0096	0.0078	0.0078
Toxoplasma gondii	FATC domain-containing protein	0.0134	0.0136	0.0332
Echinococcus multilocularis	tyrosine kinase	0.0053	0.0013	0.0013
Onchocerca volvulus		0.0065	0.0031	0.0138
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0134	0.0136	0.0279
Schistosoma mansoni	family M13 non-peptidase homologue (M13 family)	0.0147	0.0155	0.0155
Brugia malayi	hypothetical protein	0.0053	0.0013	0.0001
Loa Loa (eye worm)	TK/RYK protein kinase	0.0053	0.0013	0.0002
Echinococcus multilocularis	protein kinase	0.0053	0.0013	0.0013
Trichomonas vaginalis	CMGC family protein kinase	0.0057	0.0019	0.0014
Trypanosoma brucei	protein kinase, putative	0.0057	0.0019	0.0046
Brugia malayi	Fibronectin type III domain containing protein	0.0076	0.0048	0.0037
Schistosoma mansoni	ataxia telangiectasia mutated (atm)-related	0.0134	0.0136	0.0136
Loa Loa (eye worm)	phosphatidylinositol 4-kinase type 3 alpha isoform 1	0.0591	0.0826	0.0817
Echinococcus multilocularis	tyrosine protein kinase shark	0.0065	0.0031	0.0031
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Echinococcus multilocularis	mitogen activated protein kinase 14	0.0402	0.0541	0.0541
Loa Loa (eye worm)	TK protein kinase	0.0053	0.0013	0.0002
Schistosoma mansoni	tyrosine kinase	0.3627	0.5418	0.5418
Giardia lamblia	Histone deacetylase	0.0796	0.1137	0.3481
Trypanosoma brucei	Pseudokinase, putative	0.0053	0.0013	0.0031
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.2143	0.3175	0.3175
Loa Loa (eye worm)	tyrosyl-DNA phosphodiesterase	0.007	0.0039	0.0029
Loa Loa (eye worm)	TK protein kinase	0.0053	0.0013	0.0002
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Entamoeba histolytica	protein kinase domain containing protein	0.0053	0.0013	0.0029
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0072	0.0042	0.0042
Echinococcus multilocularis	heat shock protein 70	0.0053	0.0013	0.0013
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0053	0.0013	0.0013
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Schistosoma mansoni	cell adhesion molecule	0.0052	0.0011	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0215	0.0259	0.0249
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Echinococcus granulosus	fructose 16 bisphosphatase 1	0.2749	0.4091	0.4091
Loa Loa (eye worm)	hypothetical protein	0.0357	0.0472	0.0462
Schistosoma mansoni	tyrosine kinase	0.6656	1	1
Echinococcus multilocularis	c src tyrosine kinase	0.0072	0.0042	0.0042
Entamoeba histolytica	protein kinase, putative	0.0053	0.0013	0.0029
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor1	0.0134	0.0136	0.0307
Loa Loa (eye worm)	phosphatidylinositol 3	0.0134	0.0136	0.0126
Loa Loa (eye worm)	TK/FER protein kinase	0.0053	0.0013	0.0002
Toxoplasma gondii	phosphatidylinositol 3- and 4-kinase	0.0134	0.0136	0.0332
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0048	0.0038
Trichomonas vaginalis	CMGC family protein kinase	0.0057	0.0019	0.0014
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0053	0.0013	0.0001
Schistosoma mansoni	tyrosine kinase	0.0072	0.0042	0.0042
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0068	0.0036	0.0036
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0103	0.0089	0.0089
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0053	0.0013	0.0013
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0074	0.0045	0.0045
Echinococcus multilocularis	histone deacetylase 6	0.0709	0.1005	0.1005
Loa Loa (eye worm)	histone deacetylase 7A	0.0693	0.0981	0.0972
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.2143	0.3175	0.3175
Trypanosoma brucei	Phosphatidylinositol 3-kinase tor1	0.0134	0.0136	0.0332
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Echinococcus multilocularis	tyrosine protein kinase csk	0.0053	0.0013	0.0013
Brugia malayi	integrin-linked kinase	0.0053	0.0013	0.0001
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0053	0.0013	0.0013
Brugia malayi	Protein kinase domain containing protein	0.0053	0.0013	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0013	0.0002
Schistosoma mansoni	tyrosine kinase	0.0053	0.0013	0.0013
Brugia malayi	Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein	0.0062	0.0027	0.0015
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0053	0.0013	0.0013
Echinococcus granulosus	twitchin	0.0093	0.0074	0.0074
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0512	0.0707	0.0707
Schistosoma mansoni	neprilysin-2 (M13 family)	0.0147	0.0155	0.0155
Echinococcus granulosus	defective proboscis extension response	0.0068	0.0036	0.0036

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL2272341

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1808112