Detailed information for compound 1913922

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 215.237 | Formula: C12H12N2O2
  • H donors: 2 H acceptors: 2 LogP: 1.22 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1N[11C](=O)C2(N1)CCCc1c2cccc1
  • InChi: 1S/C12H12N2O2/c15-10-12(14-11(16)13-10)7-3-5-8-4-1-2-6-9(8)12/h1-2,4,6H,3,5,7H2,(H2,13,14,15,16)/i10-1
  • InChiKey: OZYWLMZRNIFQPM-LMANFOLPSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi MH2 domain containing protein 0.0012 0.0094 0.0156
Entamoeba histolytica hypothetical protein 0.0045 0.0649 0.365
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0611 0.061
Plasmodium vivax histone deacetylase, putative 0.0045 0.0652 0.3671
Leishmania major histone deacetylase, putative 0.0045 0.0652 0.3671
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0183 0.0302
Loa Loa (eye worm) TK/INSR protein kinase 0.0057 0.0855 0.1417
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0008 0.0022 0.003
Schistosoma mansoni hypothetical protein 0.0161 0.2596 0.3138
Entamoeba histolytica AMP deaminase, putative 0.0036 0.0498 0.2776
Mycobacterium tuberculosis Conserved protein 0.0043 0.0611 0.1322
Loa Loa (eye worm) hypothetical protein 0.036 0.594 0.9866
Schistosoma mansoni histone deacetylase 4 5 0.0045 0.0652 0.0773
Schistosoma mansoni tyrosine kinase 0.0025 0.0321 0.0369
Mycobacterium tuberculosis Putative ferredoxin reductase 0.013 0.2081 0.4625
Brugia malayi latrophilin 2 splice variant baaae 0.0106 0.1669 0.2773
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0012 0.0094 0.0092
Schistosoma mansoni tar DNA-binding protein 0.0047 0.0683 0.0811
Trypanosoma cruzi trypanothione reductase, putative 0.002 0.0226 0.1317
Schistosoma mansoni cpg binding protein 0.0022 0.0261 0.0296
Schistosoma mansoni microtubule-associated protein tau 0.0497 0.8232 1
Trypanosoma brucei AMP deaminase, putative 0.0036 0.0498 0.3029
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0275 0.1073
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0056 0.0843 0.5206
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0275 0.1467
Toxoplasma gondii histone deacetylase HDAC5 0.0045 0.0652 0.3671
Schistosoma mansoni smad1 5 8 and 0.0012 0.0094 0.0093
Echinococcus granulosus survival motor neuron protein 1 0.017 0.2751 0.3341
Toxoplasma gondii ABC1 family protein 0.0043 0.0611 0.3431
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0078 0.12 0.1994
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0611 0.3744
Schistosoma mansoni hypothetical protein 0.0049 0.0716 0.085
Toxoplasma gondii histone deacetylase HDAC2 0.0102 0.1602 0.9164
Giardia lamblia Histone deacetylase 0.0102 0.1602 1
Echinococcus granulosus zinc finger transcription factor gli2 0.023 0.3748 0.4552
Loa Loa (eye worm) hypothetical protein 0.0337 0.5559 0.9233
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0102 0.1602 0.9164
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0019 0.0211 0.112
Trypanosoma cruzi AMP deaminase 2, putative 0.0036 0.0498 0.3029
Trichomonas vaginalis histone deacetylase, putative 0.0102 0.1602 0.9164
Loa Loa (eye worm) hypothetical protein 0.014 0.2241 0.3721
Brugia malayi Protein kinase domain containing protein 0.0057 0.0855 0.1419
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0275 0.1491
Schistosoma mansoni histone deacetylase hda2 0.0045 0.0652 0.0773
Echinococcus multilocularis histone deacetylase 6 0.0045 0.0652 0.0651
Echinococcus multilocularis muscleblind protein 0.014 0.2241 0.224
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0611 0.3431
Schistosoma mansoni tar DNA-binding protein 0.0047 0.0683 0.0811
Brugia malayi MH2 domain containing protein 0.0012 0.0094 0.0156
Mycobacterium ulcerans lipase LipD 0.0043 0.0611 0.3413
Schistosoma mansoni tyrosine kinase 0.0059 0.0893 0.1066
Onchocerca volvulus 0.0078 0.12 0.1683
Brugia malayi MH1 domain containing protein 0.0007 0.0004 0.0007
Brugia malayi RNA recognition motif domain containing protein 0.0047 0.0683 0.1135
Loa Loa (eye worm) TK/EGFR protein kinase 0.0026 0.0334 0.0552
Plasmodium vivax importin-beta 2, putative 0.0015 0.0147 0.0749
Schistosoma mansoni hypothetical protein 0.0049 0.0716 0.085
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0652 0.4005
Brugia malayi Adenosine/AMP deaminase family protein 0.011 0.1747 0.2902
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0611 0.3744
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0045 0.0644 0.0643
Onchocerca volvulus 0.0036 0.0498 0.045
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0056 0.0843 0.4771
Loa Loa (eye worm) hypothetical protein 0.0106 0.1669 0.2771
Echinococcus granulosus muscleblind protein 0.014 0.2241 0.2721
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0232 0.3783 0.3783
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0019 0.0211 0.112
Leishmania major cytochrome p450-like protein 0.0008 0.0022 0.0027
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0611 0.0722
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.013 0.2081 0.4625
Loa Loa (eye worm) phosphatidylinositol 3 0.0095 0.1484 0.2464
Echinococcus multilocularis zinc finger transcription factor gli2 0.023 0.3748 0.3747
Brugia malayi beta-lactamase family protein 0.0043 0.0611 0.1015
Schistosoma mansoni smad1 5 8 and 0.0012 0.0094 0.0093
Trypanosoma cruzi AMP deaminase, putative 0.0036 0.0498 0.3029
Mycobacterium tuberculosis Conserved protein 0.0043 0.0611 0.1322
Echinococcus multilocularis protein quaking 0.0031 0.0412 0.0411
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0275 0.1627
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0061 0.0911 0.0909
Trichomonas vaginalis histone deacetylase, putative 0.0102 0.1602 0.9164
Schistosoma mansoni hypothetical protein 0.0106 0.1669 0.2011
Entamoeba histolytica hypothetical protein 0.0012 0.0099 0.0472
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.002 0.0226 0.1207
Mycobacterium tuberculosis Probable dehydrogenase 0.013 0.2081 0.4625
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0275 0.1491
Echinococcus granulosus microtubule associated protein 2 0.0497 0.8232 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0611 0.1013
Trichomonas vaginalis esterase, putative 0.0043 0.0611 0.3431
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0226 0.1317
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0039 0.0546 0.3053
Echinococcus multilocularis Zinc finger, PHD finger 0.0007 0.0018 0.0016
Schistosoma mansoni tyrosine kinase 0.0026 0.0334 0.0385
Schistosoma mansoni tar DNA-binding protein 0.0047 0.0683 0.0811
Brugia malayi Histone deacetylase family protein 0.0045 0.0652 0.1084
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0273 0.4475 1
Toxoplasma gondii histone deacetylase HDAC1 0.0045 0.0652 0.3671
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.002 0.0226 0.1183
Schistosoma mansoni histone deacetylase 1 2 3 0.0045 0.0652 0.0773
Brugia malayi MH1 domain containing protein 0.0012 0.0094 0.0156
Echinococcus multilocularis Smad4 0.0012 0.0094 0.0092
Brugia malayi Calcitonin receptor-like protein seb-1 0.0155 0.2491 0.4138
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0226 0.1317
Toxoplasma gondii AMP deaminase 0.0036 0.0498 0.2776
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.013 0.2081 0.894
Schistosoma mansoni histone deacetylase 0.0102 0.1602 0.1929
Echinococcus granulosus L aminoadipate semialdehyde 0.0078 0.12 0.1457
Echinococcus multilocularis histone deacetylase 3 0.0102 0.1602 0.1601
Echinococcus granulosus thioredoxin glutathione reductase 0.0057 0.0853 0.1035
Echinococcus multilocularis 0.0008 0.0022 0.0021
Schistosoma mansoni adenosine deaminase 0.011 0.1747 0.2105
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0261 0.1539
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0275 0.0333
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0275 0.1491
Entamoeba histolytica hypothetical protein 0.0045 0.0644 0.3625
Loa Loa (eye worm) histone deacetylase 11 0.0045 0.0652 0.1082
Loa Loa (eye worm) nuclear factor I 0.0007 0.0004 0.0005
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0007 0.0018 0.002
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0611 0.1322
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0022 0.003
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0007 0.0018 0.0016
Brugia malayi Furin-like cysteine rich region family protein 0.0026 0.0334 0.0554
Brugia malayi Protein kinase domain containing protein 0.0032 0.0428 0.071
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0611 0.3431
Leishmania major hypothetical protein, conserved 0.0043 0.0611 0.3431
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0275 0.1627
Schistosoma mansoni ap endonuclease 0.0023 0.0275 0.0314
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0022 0.0261 0.141
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0716 0.1189
Brugia malayi hypothetical protein 0.017 0.2751 0.457
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0019 0.0211 0.112
Leishmania major adenine aminohydrolase 0.011 0.1747 1
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0611 0.1322
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0078 0.12 0.144
Brugia malayi MH2 domain containing protein 0.0175 0.2824 0.4692
Trichomonas vaginalis histone deacetylase, putative 0.0102 0.1602 0.9164
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0611 0.3431
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0275 0.0323
Plasmodium falciparum adenosine deaminase 0.011 0.1747 1
Echinococcus multilocularis epidermal growth factor receptor 0.0026 0.0334 0.0332
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0022 0.003
Loa Loa (eye worm) hypothetical protein 0.0007 0.0004 0.0005
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.002 0.0226 0.0376
Leishmania major hypothetical protein, conserved 0.0036 0.0498 0.2776
Loa Loa (eye worm) hypothetical protein 0.0031 0.0415 0.0687
Echinococcus granulosus epidermal growth factor receptor 0.0026 0.0334 0.0404
Trypanosoma brucei histone deacetylase 3 0.0045 0.0652 0.4005
Loa Loa (eye worm) tumor suppressor 0.0365 0.602 1
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0019 0.0211 0.112
Schistosoma mansoni smad1 5 8 and 0.0012 0.0094 0.0093
Brugia malayi hypothetical protein 0.036 0.594 0.9866
Plasmodium vivax thioredoxin reductase, putative 0.0057 0.0853 0.483
Trichomonas vaginalis mercuric reductase, putative 0.002 0.0226 0.1207
Plasmodium vivax adenosine deaminase, putative 0.011 0.1747 1
Loa Loa (eye worm) hypothetical protein 0.0074 0.1143 0.1897
Trypanosoma cruzi AMP deaminase, putative 0.0036 0.0498 0.3029
Echinococcus granulosus epidermal growth factor receptor 0.0026 0.0334 0.0404
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.002 0.0226 0.1207
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.002 0.0226 0.1207
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0145 0.2325 1
Loa Loa (eye worm) Smad1 0.0012 0.0094 0.0153
Echinococcus granulosus mothers against decapentaplegic 5 0.0012 0.0094 0.0112
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.002 0.0226 0.1207
Mycobacterium ulcerans adenosine deaminase 0.011 0.1747 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0275 0.1491
Brugia malayi RNA, U transporter 1 0.0043 0.0614 0.1019
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0161 0.2596 0.431
Schistosoma mansoni hypothetical protein 0.0045 0.0644 0.0763
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0275 0.1491
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.074 0.0897
Trypanosoma brucei importin beta-1 subunit, putative 0.0015 0.0147 0.0817
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.002 0.0226 0.0225
Trichomonas vaginalis histone deacetylase, putative 0.0102 0.1602 0.9164
Plasmodium falciparum glutathione reductase 0.0057 0.0853 0.483
Echinococcus multilocularis histone deacetylase 6 0.0045 0.0652 0.0651
Leishmania major histone deacetylase, putative 0.0045 0.0652 0.3671
Echinococcus granulosus smad 0.0012 0.0094 0.0112
Brugia malayi adenosine monophosphate deaminase 0.0036 0.0498 0.0827
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0232 0.3783 0.4595
Trypanosoma cruzi cytochrome P450, putative 0.0008 0.0022 0.003
Entamoeba histolytica hypothetical protein 0.0045 0.0644 0.3625
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0022 0.0035
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0056 0.0843 0.4771
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0007 0.0018 0.002
Brugia malayi cytochrome P450 0.0008 0.0022 0.0037
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0022 0.0261 1
Mycobacterium ulcerans hypothetical protein 0.0043 0.0611 0.3413
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0611 0.3744
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0106 0.1678 0.1677
Loa Loa (eye worm) hypothetical protein 0.017 0.2751 0.4569
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0652 0.4005
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0652 0.4005
Loa Loa (eye worm) RNA binding protein 0.0047 0.0683 0.1133
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.074 0.0879
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0037 0.0508 0.0507
Brugia malayi RNA binding protein 0.0047 0.0683 0.1135
Echinococcus granulosus GPCR family 2 0.0049 0.0716 0.0868
Trypanosoma cruzi histone deacetylase 1, putative 0.0102 0.1602 1
Trypanosoma cruzi histone deacetylase 1, putative 0.0102 0.1602 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0611 0.1322
Loa Loa (eye worm) hypothetical protein 0.0078 0.12 0.1992
Trypanosoma cruzi AMP deaminase, putative 0.0036 0.0498 0.3029
Echinococcus granulosus insulin receptor 0.0057 0.0855 0.1037
Plasmodium vivax adenosine/AMP deaminase, putative 0.0036 0.0498 0.2776
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0106 0.1678 0.2022
Echinococcus granulosus AMP deaminase 2 0.0036 0.0498 0.0603
Loa Loa (eye worm) histone deacetylase 3 0.0102 0.1602 0.266
Loa Loa (eye worm) MH2 domain-containing protein 0.0175 0.2824 0.469
Schistosoma mansoni hypothetical protein 0.0294 0.4836 0.5866
Echinococcus granulosus hypothetical protein 0.0031 0.0412 0.0499
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0611 0.2556
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0027 0.0352 0.1587
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0106 0.1678 0.2037
Loa Loa (eye worm) hypothetical protein 0.0074 0.1143 0.1897
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0611 0.1015
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0037 0.0508 0.0616
Echinococcus granulosus histone deacetylase 3 0.0102 0.1602 0.1945
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0056 0.0843 0.5206
Loa Loa (eye worm) hypothetical protein 0.002 0.0228 0.0377
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0716 0.0868
Brugia malayi Muscleblind-like protein 0.014 0.2241 0.3723
Brugia malayi histone deacetylase 1 (HD1) 0.0102 0.1602 0.2662
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0061 0.0911 0.1105
Brugia malayi Histone deacetylase family protein 0.0045 0.0652 0.1084
Schistosoma mansoni tyrosine kinase 0.0025 0.0321 0.0369
Trypanosoma cruzi AMP deaminase, putative 0.0036 0.0498 0.3029
Onchocerca volvulus Adenosine deaminase homolog 0.011 0.1747 0.2643
Echinococcus multilocularis insulin receptor 0.0057 0.0855 0.0853
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.011 0.1747 1
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0019 0.0211 0.1223
Echinococcus multilocularis 0.0007 0.0019 0.0017
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0716 0.0714
Schistosoma mansoni tyrosine kinase 0.0025 0.0321 0.0369
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0226 0.1317
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0007 0.0018 0.0027
Brugia malayi Cytochrome P450 family protein 0.0008 0.0022 0.0037
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0275 1
Echinococcus multilocularis GPCR, family 2 0.0049 0.0716 0.0714
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.074 0.0738
Trypanosoma cruzi adenosine monophosphate deaminase, putative 0.0036 0.0498 0.3029
Leishmania major cytochrome p450-like protein 0.0008 0.0022 0.0027
Leishmania major acetoin dehydrogenase e3 component-like protein 0.002 0.0226 0.1207
Brugia malayi Histone deacetylase 1 0.0102 0.1602 0.2662
Brugia malayi tumor suppressor. 0.0365 0.602 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0611 0.1013
Echinococcus granulosus Smad4 0.0012 0.0094 0.0112
Leishmania major cytochrome p450-like protein 0.0008 0.0022 0.0027
Echinococcus granulosus cpg binding protein 0.0022 0.0261 0.0315
Echinococcus multilocularis histone deacetylase 6 0.0045 0.0652 0.0651
Toxoplasma gondii exonuclease III APE 0.0023 0.0275 0.1491
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0226 0.1317
Loa Loa (eye worm) CYP4Cod1 0.0008 0.0022 0.0035
Echinococcus multilocularis thioredoxin glutathione reductase 0.0057 0.0853 0.0852
Echinococcus granulosus dnaJ subfamily B 0.0294 0.4836 0.5874
Brugia malayi MH1 domain containing protein 0.0007 0.0004 0.0007
Trichomonas vaginalis histone deacetylase, putative 0.0102 0.1602 0.9164
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0611 0.1322
Echinococcus granulosus histone deacetylase 6 0.0045 0.0652 0.0791
Trypanosoma cruzi AMP deaminase, putative 0.0036 0.0498 0.3029
Trichomonas vaginalis importin beta-1, putative 0.0012 0.0099 0.0472
Brugia malayi hypothetical protein 0.0031 0.0412 0.0685
Loa Loa (eye worm) cytochrome P450 0.0008 0.0022 0.0035
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0022 0.0035
Toxoplasma gondii histone lysine methyltransferase SET1 0.0039 0.0551 0.3087
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0853 0.5271
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.0211 0.1223
Brugia malayi beta-lactamase 0.0043 0.0611 0.1015
Loa Loa (eye worm) hypothetical protein 0.014 0.2241 0.3721
Schistosoma mansoni survival motor neuron protein 0.0035 0.0477 0.0559
Leishmania major histone deacetylase, putative 0.0102 0.1602 0.9164
Schistosoma mansoni transcription factor LCR-F1 0.0045 0.0644 0.0763
Entamoeba histolytica hypothetical protein 0.0022 0.0261 0.141
Loa Loa (eye worm) glutathione reductase 0.0057 0.0853 0.1415
Echinococcus granulosus histone deacetylase 6 0.0045 0.0652 0.0791
Echinococcus multilocularis cpg binding protein 0.0022 0.0261 0.0259
Schistosoma mansoni tyrosine kinase 0.0057 0.0855 0.1019
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.013 0.2081 0.4625
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.074 0.1227
Schistosoma mansoni histone deacetylase 4 5 0.0045 0.0652 0.0773
Echinococcus granulosus histone deacetylase 6 0.0045 0.0652 0.0791
Plasmodium vivax histone deacetylase, putative 0.0045 0.0652 0.3671
Loa Loa (eye worm) thioredoxin reductase 0.0057 0.0853 0.1415
Loa Loa (eye worm) MH2 domain-containing protein 0.0012 0.0094 0.0153
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0611 0.3413
Plasmodium vivax histone deacetylase 1, putative 0.0102 0.1602 0.9164
Trypanosoma brucei cytochrome P450, putative 0.0008 0.0022 0.003
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0611 0.1322
Toxoplasma gondii thioredoxin reductase 0.0057 0.0853 0.483
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0022 0.0261 0.141
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0261 0.1038
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0008 0.0022 0.003
Trichomonas vaginalis glutathione reductase, putative 0.002 0.0226 0.1207
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0045 0.0649 0.365
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0102 0.1602 0.9164
Echinococcus multilocularis tar DNA binding protein 0.0047 0.0683 0.0682
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0226 0.1317
Loa Loa (eye worm) zinc finger protein 0.023 0.3748 0.6225
Toxoplasma gondii cytochrome p450 superfamily protein 0.0008 0.0022 0.0027
Trypanosoma brucei importin beta-1 subunit, putative 0.0015 0.0147 0.0817
Schistosoma mansoni ap endonuclease 0.0023 0.0275 0.0314
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0275 0.1627
Trypanosoma cruzi adenosine monophosphate deaminase-like protein, putative 0.0036 0.0498 0.3029
Loa Loa (eye worm) TAR-binding protein 0.0047 0.0683 0.1133
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0047 0.0683 0.1133
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.002 0.0226 0.1317
Plasmodium vivax histone deacetylase 2, putative 0.0045 0.0652 0.3671
Schistosoma mansoni smad 0.0012 0.0094 0.0093
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0012 0.0099 0.0472
Echinococcus granulosus importin subunit beta 1 0.0015 0.0147 0.0177
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0716 0.1187
Schistosoma mansoni cytochrome P450 0.0008 0.0022 0.0006
Loa Loa (eye worm) hypothetical protein 0.0049 0.0716 0.1187
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0025 0.0315 0.1718
Echinococcus multilocularis mothers against decapentaplegic 5 0.0012 0.0094 0.0092
Loa Loa (eye worm) transcription factor SMAD2 0.0175 0.2824 0.469
Mycobacterium ulcerans flavoprotein disulfide reductase 0.002 0.0226 0.1183
Brugia malayi TAR-binding protein 0.0047 0.0683 0.1135
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0044 0.063 0.0746
Brugia malayi histone deacetylase 11 0.0045 0.0652 0.1084
Brugia malayi Cytochrome P450 family protein 0.0035 0.0483 0.0803
Onchocerca volvulus Histone deacetylase 10 homolog 0.0045 0.0652 0.0722
Schistosoma mansoni histone deacetylase 0.0102 0.1602 0.1929
Trypanosoma brucei histone deacetylase, putative 0.0045 0.0652 0.4005
Echinococcus granulosus TGF beta signal transducer SmadC 0.0012 0.0094 0.0112
Echinococcus multilocularis adenosine deaminase 0.011 0.1747 0.1746
Leishmania major trypanothione reductase 0.0057 0.0853 0.483
Trypanosoma cruzi importin beta-1 subunit, putative 0.0012 0.0099 0.0515
Onchocerca volvulus AMP deaminase 2 homolog 0.0036 0.0498 0.045
Trypanosoma brucei trypanothione reductase 0.0057 0.0853 0.5271
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0102 0.1602 0.9164
Echinococcus multilocularis L aminoadipate semialdehyde 0.0078 0.12 0.1199
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0275 0.1491
Echinococcus granulosus histone deacetylase 8 0.0045 0.0652 0.0791
Echinococcus granulosus adenosine deaminase 0.011 0.1747 0.2121
Schistosoma mansoni adenosine deaminase-related 0.011 0.1747 0.2105
Schistosoma mansoni hypothetical protein 0.0049 0.0716 0.085
Trichomonas vaginalis adenosine deaminase, putative 0.011 0.1747 1
Leishmania major importin beta-1 subunit, putative 0.0012 0.0099 0.0472
Brugia malayi Thioredoxin reductase 0.0057 0.0853 0.1417
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.002 0.0226 0.1207
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0007 0.0018 0.0029
Entamoeba histolytica hypothetical protein 0.0045 0.0644 0.3625
Plasmodium falciparum histone deacetylase 2 0.0045 0.0652 0.3671
Mycobacterium ulcerans beta-lactamase 0.0043 0.0611 0.3413
Schistosoma mansoni hypothetical protein 0.0008 0.0022 0.0006
Entamoeba histolytica adenosine deaminase, putative 0.011 0.1747 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0611 0.3413
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0716 0.1189
Brugia malayi Temporarily assigned gene name protein 44 0.0031 0.0412 0.0685
Onchocerca volvulus 0.036 0.594 1
Leishmania major AMP deaminase, putative,adenosine monophosphate deaminase-like protein 0.0036 0.0498 0.2776
Brugia malayi hypothetical protein 0.0045 0.0644 0.1071
Loa Loa (eye worm) histone deacetylase 1 0.0102 0.1602 0.266
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.002 0.0226 0.0254
Entamoeba histolytica adenosine deaminase, putative 0.011 0.1747 1
Echinococcus multilocularis dnaJ subfamily B 0.0294 0.4836 0.4836
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.002 0.0226 0.1183
Trypanosoma brucei AMP deaminase, putative 0.0036 0.0498 0.3029
Brugia malayi Smad1 0.0012 0.0094 0.0156
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0056 0.0843 0.4771
Brugia malayi Cytochrome P450 family protein 0.0008 0.0022 0.0037
Plasmodium falciparum importin beta, putative 0.0015 0.0147 0.0749
Leishmania major AMP deaminase, putative,amp deaminase-like protein 0.0036 0.0498 0.2776
Echinococcus multilocularis importin subunit beta 1 0.0015 0.0147 0.0146
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0015 0.0138 0.0229
Brugia malayi CXXC zinc finger family protein 0.0021 0.0241 0.04
Brugia malayi Importin beta-1 subunit 0.0015 0.0147 0.0244
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0275 0.0455
Trypanosoma brucei histone deacetylase 2 0.0045 0.0652 0.4005
Echinococcus granulosus histone deacetylase 1 0.0102 0.1602 0.1945
Schistosoma mansoni tyrosine kinase 0.0026 0.0334 0.0385
Loa Loa (eye worm) histone deacetylase 7A 0.0045 0.0652 0.1082
Trypanosoma brucei AMP deaminase, putative 0.0036 0.0498 0.3029
Loa Loa (eye worm) CXXC zinc finger family protein 0.0021 0.0241 0.0398
Trypanosoma brucei histone deacetylase 1 0.0102 0.1602 1
Plasmodium falciparum histone deacetylase 1 0.0102 0.1602 0.9164
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0226 0.1317
Trypanosoma cruzi cytochrome P450, putative 0.0008 0.0022 0.003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0147 0.0242
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0012 0.0099 0.0472
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0611 0.0722
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0155 0.2491 0.4136
Schistosoma mansoni histone deacetylase hda2 0.0045 0.0652 0.0773
Echinococcus multilocularis microtubule associated protein 2 0.0497 0.8232 0.8232
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.011 0.1747 1
Onchocerca volvulus 0.0043 0.0611 0.0649
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.013 0.2081 0.4625
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0611 0.3431
Mycobacterium tuberculosis Probable oxidoreductase 0.0145 0.2325 0.5173
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0652 0.4005
Entamoeba histolytica AMP deaminase, putative 0.0036 0.0498 0.2776
Schistosoma mansoni importin beta-1 0.0015 0.0147 0.0158
Plasmodium falciparum histone deacetylase, putative 0.0045 0.0652 0.3671
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0057 0.0855 0.0853
Brugia malayi Cytochrome P450 family protein 0.0008 0.0022 0.0037
Trichomonas vaginalis histone deacetylase, putative 0.0102 0.1602 0.9164
Trypanosoma brucei histone deacetylase 4 0.0045 0.0652 0.4005
Brugia malayi Zinc finger, C2H2 type family protein 0.023 0.3748 0.6226
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0611 0.0741
Loa Loa (eye worm) hypothetical protein 0.0036 0.0498 0.0825
Echinococcus multilocularis muscleblind protein 1 0.014 0.2241 0.224
Echinococcus granulosus protein quaking 0.0031 0.0412 0.0499
Loa Loa (eye worm) AMP deaminase 0.0036 0.0498 0.0825
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0275 0.0274
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.074 0.1229
Echinococcus granulosus tar DNA binding protein 0.0047 0.0683 0.0829
Onchocerca volvulus 0.0043 0.0611 0.0649
Loa Loa (eye worm) hypothetical protein 0.0031 0.0412 0.0683
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.002 0.0226 0.1207
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0008 0.0022 0.0027
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0275 0.0568
Schistosoma mansoni tyrosine kinase 0.0026 0.0334 0.0385
Toxoplasma gondii histone deacetylase HDAC4 0.0045 0.0652 0.3671
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0037 0.0508 0.0845
Giardia lamblia NADH oxidase lateral transfer candidate 0.002 0.0226 0.0743
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0337 0.5559 0.9233
Schistosoma mansoni tyrosine kinase 0.0057 0.0855 0.1019
Schistosoma mansoni hypothetical protein 0.0031 0.0412 0.048
Schistosoma mansoni hypothetical protein 0.0035 0.0477 0.0559
Schistosoma mansoni cpg binding protein 0.0021 0.0241 0.0272
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0611 0.3431
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0055 0.0815 0.4608
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0019 0.0211 0.112
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0017 0.0183 0.1045
Leishmania major phosphopantetheinyl transferase-like protein 0.0022 0.0261 0.141
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0611 0.1322
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0056 0.0843 0.14
Mycobacterium leprae Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) 0.011 0.1747 0.7489
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0211 0.0351
Mycobacterium tuberculosis Probable reductase 0.013 0.2081 0.4625
Plasmodium falciparum AMP deaminase, putative 0.0036 0.0498 0.2776
Plasmodium falciparum thioredoxin reductase 0.0057 0.0853 0.483
Plasmodium falciparum thioredoxin reductase 0.002 0.0226 0.1207
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0056 0.0843 0.4771
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0611 0.1322
Echinococcus multilocularis histone deacetylase 0.0045 0.0652 0.0651
Trichomonas vaginalis adenosine deaminase, putative 0.011 0.1747 1
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0026 0.0334 0.0404
Mycobacterium tuberculosis Conserved protein 0.0043 0.0611 0.1322
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.074 0.0879
Brugia malayi MH1 domain containing protein 0.0012 0.0094 0.0156
Loa Loa (eye worm) hypothetical protein 0.0043 0.0611 0.1013
Brugia malayi histone deacetylase 3 (HD3) 0.0102 0.1602 0.2662
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0057 0.0853 0.1866
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0226 0.1317
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0019 0.0211 0.0236
Loa Loa (eye worm) hypothetical protein 0.011 0.1747 0.29
Echinococcus multilocularis survival motor neuron protein 1 0.017 0.2751 0.275
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0652 0.4005
Loa Loa (eye worm) hypothetical protein 0.0043 0.0611 0.1013
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0039 0.0546 0.3053
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0275 0.0457
Echinococcus granulosus cytochrome P450 2K1 0.0008 0.0022 0.0025
Schistosoma mansoni hypothetical protein 0.0031 0.0412 0.048
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.002 0.0226 0.1317
Loa Loa (eye worm) hypothetical protein 0.0043 0.0611 0.1013
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0226 0.1207
Loa Loa (eye worm) MH1 domain-containing protein 0.0012 0.0094 0.0153
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0022 0.0261 0.141
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.074 0.0879
Leishmania major adenosine monophosphate deaminase, putative,AMP deaminase, putative 0.0036 0.0498 0.2776
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0226 0.1207
Echinococcus multilocularis histone deacetylase 7 0.0045 0.0652 0.0651
Echinococcus granulosus histone deacetylase 0.0045 0.0652 0.0791
Schistosoma mansoni tar DNA-binding protein 0.0047 0.0683 0.0811
Toxoplasma gondii HEAT repeat-containing protein 0.0015 0.0147 0.0749
Onchocerca volvulus 0.0043 0.0611 0.0649
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0226 0.1317
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0145 0.2325 0.5173
Leishmania major histone deacetylase, putative 0.0102 0.1602 0.9164
Loa Loa (eye worm) hypothetical protein 0.0045 0.0652 0.1082
Loa Loa (eye worm) hypothetical protein 0.0074 0.1143 0.1897
Plasmodium vivax glutathione reductase, putative 0.0057 0.0853 0.483
Echinococcus multilocularis smad 0.0012 0.0094 0.0092
Loa Loa (eye worm) beta-lactamase 0.0043 0.0611 0.1013
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0145 0.2325 0.5173
Treponema pallidum adenosine deaminase 0.011 0.1747 1
Brugia malayi glutathione reductase 0.0057 0.0853 0.1417
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0022 0.0261 0.0537
Toxoplasma gondii histone deacetylase HDAC3 0.0102 0.1602 0.9164
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0015 0.0138 0.0229
Schistosoma mansoni AMP deaminase 0.0036 0.0498 0.0584
Mycobacterium tuberculosis Probable adenosine deaminase Add (adenosine aminohydrolase) 0.011 0.1747 0.3874
Brugia malayi beta-lactamase family protein 0.0043 0.0611 0.1015
Loa Loa (eye worm) hypothetical protein 0.0037 0.0508 0.0842
Schistosoma mansoni Smad4 0.0012 0.0094 0.0093
Loa Loa (eye worm) hypothetical protein 0.0102 0.1602 0.266
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0611 0.3431
Echinococcus multilocularis histone deacetylase 8 0.0045 0.0652 0.0651
Mycobacterium leprae Probable lipase LipE 0.0043 0.0611 0.2556
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0022 0.0261 0.1386
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0022 0.0261 0.1386
Echinococcus multilocularis histone deacetylase 1 0.0102 0.1602 0.1601
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0226 0.1317
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0022 0.0261 0.7155
Trypanosoma brucei adenosine monophosphate deaminase, putative 0.0036 0.0498 0.3029
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0022 0.0261 0.141
Echinococcus multilocularis epidermal growth factor receptor 0.0026 0.0334 0.0332
Schistosoma mansoni cpg binding protein 0.0022 0.0261 0.0296
Echinococcus multilocularis snurportin 1 0.0161 0.2596 0.2595
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.005 0.073 0.1212
Plasmodium falciparum glutathione reductase 0.002 0.0226 0.1207
Loa Loa (eye worm) hypothetical protein 0.0043 0.0611 0.1013
Schistosoma mansoni hypothetical protein 0.0049 0.0716 0.085
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0057 0.0855 0.1037
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.002 0.0226 0.0458
Onchocerca volvulus 0.0035 0.0477 0.0414
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0226 0.1317
Entamoeba histolytica histone deacetylase, putative 0.0102 0.1602 0.9164
Entamoeba histolytica hypothetical protein 0.0045 0.0644 0.3625
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0483 0.0801
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0022 0.0261 0.0231
Loa Loa (eye worm) hypothetical protein 0.0074 0.1143 0.1897
Loa Loa (eye worm) hypothetical protein 0.0043 0.0611 0.1013
Schistosoma mansoni tar DNA-binding protein 0.0047 0.0683 0.0811
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0035 0.0477 0.0792
Echinococcus granulosus histone deacetylase 7 0.0045 0.0652 0.0791
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0012 0.0094 0.0093
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.074 0.0897
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.074 0.0738
Echinococcus granulosus snurportin 1 0.0161 0.2596 0.3152
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.002 0.0226 0.0273
Echinococcus multilocularis AMP deaminase 2 0.0036 0.0498 0.0496
Loa Loa (eye worm) histone deacetylase 0.0045 0.0652 0.1082
Leishmania major AMP deaminase, putative 0.0036 0.0498 0.2776
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0045 0.0644 0.0781
Toxoplasma gondii NADPH-glutathione reductase 0.002 0.0226 0.1207

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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