Detailed information for compound 253430

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 362.36 | Formula: C19H15FN6O
  • H donors: 1 H acceptors: 5 LogP: 3.15 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccccc1c1nc2n(c1)c(O)nc1c2CN(CC1)c1ncccn1
  • InChi: 1S/C19H15FN6O/c20-14-5-2-1-4-12(14)16-11-26-17(23-16)13-10-25(18-21-7-3-8-22-18)9-6-15(13)24-19(26)27/h1-5,7-8,11H,6,9-10H2,(H,24,27)
  • InChiKey: JWTPTEHWQUNGQF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 2 Starlite/ChEMBL References
Rattus norvegicus GABA-A receptor; anion channel Starlite/ChEMBL References
Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative GABA-A receptor; anion channel   467 aa 384 aa 19.5 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 446 aa 28.0 %
Echinococcus multilocularis glycine receptor subunit beta GABA-A receptor; anion channel   467 aa 478 aa 28.7 %
Echinococcus granulosus glycine receptor subunit alpha 1 GABA-A receptor; anion channel   467 aa 430 aa 32.3 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type homolog GABA-A receptor; anion channel   467 aa 418 aa 19.6 %
Onchocerca volvulus Large subunit GTPase 1 homolog GABA-A receptor; anion channel   467 aa 496 aa 26.0 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 446 aa 29.1 %
Echinococcus granulosus glycine receptor subunit beta GABA-A receptor; anion channel   467 aa 439 aa 29.6 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein gamma-aminobutyric acid (GABA) A receptor, alpha 2 451 aa 393 aa 25.9 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein GABA-A receptor; anion channel   467 aa 375 aa 21.9 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 435 aa 29.7 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 461 aa 27.8 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 454 aa 30.4 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 447 aa 25.7 %
Schistosoma mansoni Cys-loop ligand gated ion channel subunit GABA-A receptor; anion channel   467 aa 479 aa 29.2 %
Brugia malayi excitatory GABA receptor EXP-1A gamma-aminobutyric acid (GABA) A receptor, alpha 3 492 aa 437 aa 28.8 %
Brugia malayi Cation transporter family protein GABA-A receptor; anion channel   467 aa 453 aa 28.5 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 468 aa 28.6 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 441 aa 33.8 %
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit GABA-A receptor; anion channel   467 aa 379 aa 19.3 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 494 aa 25.5 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 434 aa 26.7 %
Onchocerca volvulus Gamma-aminobutyric acid receptor subunit beta homolog GABA-A receptor; anion channel   467 aa 433 aa 34.6 %
Onchocerca volvulus Eukaryotic initiation factor 4A-III homolog GABA-A receptor; anion channel   467 aa 453 aa 26.9 %
Echinococcus multilocularis glycine receptor subunit alpha 1 GABA-A receptor; anion channel   467 aa 430 aa 32.3 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein GABA-A receptor; anion channel   467 aa 454 aa 29.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0028 0.0381 0.0381
Brugia malayi hypothetical protein 0.0203 0.4062 0.4062
Entamoeba histolytica protein kinase, putative 0.0029 0.0387 0.3515
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0496 0.1221
Entamoeba histolytica hypothetical protein 0.0021 0.0224 0.203
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Schistosoma mansoni hypothetical protein 0.0012 0.0038 0.0094
Echinococcus multilocularis ecdysone induced protein 78C 0.0023 0.0275 0.0678
Schistosoma mansoni single-minded 0.0041 0.0644 0.1586
Onchocerca volvulus 0.0203 0.4062 1
Plasmodium vivax CDK-related protein kinase 6, putative 0.0398 0.8153 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0275 0.0275
Brugia malayi hypothetical protein 0.0012 0.0043 0.0043
Echinococcus granulosus solute carrier family 22 0.0013 0.0061 0.015
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0024 0.0295 0.0726
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0023 0.0275 0.0275
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0029 0.0388 0.0476
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0021 0.0224 0.2343
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0395 0.2251
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0056 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Onchocerca volvulus 0.0013 0.0061 0.015
Echinococcus multilocularis lysyl tRNA synthetase 0.0021 0.0224 0.0551
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0014 0.0083 0.0204
Schistosoma mansoni nAChR subunit 0.0053 0.0892 0.2196
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0023 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Schistosoma mansoni glucose transport protein 0.0094 0.1756 0.4321
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0018 0.0157 0.1198
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0023 0.0275 0.0678
Leishmania major glucose transporter, lmgt1 0.0029 0.0395 0.4147
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0028 0.0381 0.0937
Onchocerca volvulus 0.0024 0.0295 0.0726
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Brugia malayi nuclear receptor NHR-88 0.0023 0.0275 0.0275
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0032 0.0465 0.1145
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0051 0.0867 1
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Echinococcus granulosus neuropeptide FF receptor 2 0.0203 0.4062 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.002 0.0211 0.052
Onchocerca volvulus 0.0028 0.0381 0.0937
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0275 0.0275
Brugia malayi G protein-coupled receptor F59B2.13 0.0203 0.4062 0.4062
Schistosoma mansoni methyl-cpg binding protein mbd 0.0015 0.0107 0.0264
Echinococcus granulosus death domain containing protein 0.0012 0.0038 0.0094
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Onchocerca volvulus Netrin receptor homolog 0.0012 0.0038 0.0094
Toxoplasma gondii sugar transporter ST1 0.0013 0.0061 0.0114
Echinococcus multilocularis G-protein coupled receptor, putative 0.0203 0.4062 1
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0053 0.0892 0.0892
Brugia malayi ecdysone receptor 0.0011 0.0016 0.0016
Loa Loa (eye worm) latrophilin receptor protein 2 0.0014 0.0083 0.0083
Leishmania major myo-inositol/proton symporter (MIT) 0.0013 0.0061 0.0628
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0023 0.0275 0.0678
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0203 0.4062 1
Brugia malayi hypothetical protein 0.0203 0.4062 0.4062
Schistosoma mansoni glucose transport protein 0.0094 0.1756 0.4321
Onchocerca volvulus 0.0013 0.0061 0.015
Brugia malayi hypothetical protein 0.0203 0.4062 0.4062
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0013 0.0061 0.015
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Onchocerca volvulus 0.0028 0.0364 0.0897
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0056 0.0951 0.2342
Trypanosoma brucei glucose transporter, putative 0.0029 0.0395 0.4147
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0028 0.0375 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Echinococcus granulosus g protein coupled receptor 0.0203 0.4062 1
Brugia malayi major facilitator superfamily protein 0.0013 0.0061 0.0061
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0053 0.0892 0.2196
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0053 0.0892 0.0892
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0011 0.0016 0.0038
Onchocerca volvulus 0.0013 0.0061 0.015
Trypanosoma brucei THT1 - hexose transporter, putative 0.0029 0.0395 0.4147
Brugia malayi hypothetical protein 0.0203 0.4062 0.4062
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0018 0.0157 0.1198
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0012 0.0045 0.046
Echinococcus granulosus neuropeptide receptor A26 0.0203 0.4062 1
Trypanosoma brucei glucose transporter, putative 0.0029 0.0395 0.4147
Schistosoma mansoni transcription factor LCR-F1 0.0063 0.1102 0.2714
Plasmodium vivax sugar transporter, putative 0.0013 0.0061 0.0075
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0203 0.4062 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0014 0.0083 0.0204
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0395 0.2251
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0013 0.0061 0.015
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Echinococcus granulosus histone lysine methyltransferase setb 0.0015 0.0107 0.0264
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0203 0.4062 1
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0094 0.1756 0.4321
Loa Loa (eye worm) hypothetical protein 0.0029 0.0387 0.0387
Brugia malayi major facilitator superfamily protein 0.0013 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0028 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Brugia malayi Cation transporter family protein 0.0053 0.0892 0.0892
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0011 0.0016 0.0038
Schistosoma mansoni biogenic amine (5HT) receptor 0.0203 0.4062 1
Brugia malayi putative neuropeptide receptor NPR1 0.0203 0.4062 0.4062
Onchocerca volvulus 0.0013 0.0061 0.015
Echinococcus granulosus Ankyrin 0.0012 0.004 0.0099
Brugia malayi RE15519p 0.0203 0.4062 0.4062
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.1756 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0203 0.4062 0.4062
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0053 0.0892 0.0892
Plasmodium falciparum calcium-dependent protein kinase 3 0.0029 0.0388 0.0476
Brugia malayi latrophilin 2 splice variant baaae 0.0031 0.043 0.043
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0023 0.0275 0.0275
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0012 0.0038 0.0094
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0203 0.4062 1
Onchocerca volvulus 0.0024 0.0295 0.0726
Echinococcus multilocularis fmrfamide receptor 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Loa Loa (eye worm) DR-78 0.0011 0.0016 0.0016
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0053 0.0892 0.0892
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0892 0.2196
Brugia malayi tailless protein 0.0011 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0053 0.0892 0.2196
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0011 0.0016 0.0038
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0012 0.0045 0.046
Trypanosoma cruzi ISWI complex protein 0.0014 0.0074 0.0764
Brugia malayi hypothetical protein 0.0203 0.4062 0.4062
Onchocerca volvulus Bile acid receptor homolog 0.0023 0.0275 0.0678
Echinococcus multilocularis rhodopsin orphan GPCR 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0016
Loa Loa (eye worm) CHromoDomain protein family member 0.0012 0.0036 0.0036
Plasmodium falciparum calcium-dependent protein kinase 2 0.0029 0.0388 0.0476
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0892 0.2196
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0033 0.0473 0.4969
Onchocerca volvulus 0.0203 0.4062 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0892 0.2196
Loa Loa (eye worm) hypothetical protein 0.0028 0.0364 0.0364
Schistosoma mansoni opsin-like receptor 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0061 0.0061
Schistosoma mansoni sugar transporter 0.0013 0.0061 0.015
Echinococcus granulosus neuropeptides capa receptor 0.0203 0.4062 1
Loa Loa (eye worm) heterochromatin protein 1 0.0063 0.1105 0.1105
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0063 0.1102 0.2714
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0203 0.4062 0.4062
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0061 0.0061
Brugia malayi hypothetical protein 0.0013 0.0061 0.0061
Onchocerca volvulus 0.0013 0.0061 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0395 0.2251
Plasmodium vivax lysine--tRNA ligase, putative 0.0021 0.0224 0.0275
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0056 0.0951 0.8629
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0061 0.0347
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0203 0.4062 1
Brugia malayi Dopamine receptor protein 2 0.0203 0.4062 0.4062
Echinococcus multilocularis dro:myosuppressin receptor 0.0203 0.4062 1
Onchocerca volvulus 0.0203 0.4062 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0023 0.0275 0.0678
Brugia malayi Death domain containing protein 0.0012 0.0038 0.0038
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0395 0.4147
Schistosoma mansoni hypothetical protein 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Echinococcus multilocularis FTZ F1 alpha 0.0023 0.0275 0.0678
Loa Loa (eye worm) hypothetical protein 0.0012 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0016
Echinococcus multilocularis transfer RNA-Lys 0.003 0.0421 0.1035
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0016
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0275 0.0275
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0036 0.0089
Brugia malayi Sugar transporter family protein 0.0094 0.1756 0.1756
Echinococcus multilocularis neuropeptide receptor 0.0203 0.4062 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0023 0.0275 0.0275
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0224 0.1275
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0203 0.4062 0.4062
Echinococcus multilocularis aryl hydrocarbon receptor 0.0011 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0023 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0007 0.0042
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0028 0.0375 0.0924
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0029 0.0387 0.4065
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0061 0.0347
Echinococcus granulosus g protein coupled receptor 0.0203 0.4062 1
Echinococcus granulosus methyl CpG binding domain protein 2 0.0015 0.0107 0.0264
Brugia malayi Nuclear hormone receptor E75 0.0011 0.0016 0.0016
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0015 0.0107 0.0264
Brugia malayi Steroid receptor seven-up type 2 0.0023 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0031 0.0436 0.1074
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0012 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0028 0.0381 0.0381
Onchocerca volvulus 0.0013 0.0061 0.015
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0029 0.0387 0.0954
Loa Loa (eye worm) hypothetical protein 0.0064 0.1125 0.1125
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.002 0.0211 0.052
Echinococcus multilocularis Ankyrin 0.0012 0.004 0.0099
Schistosoma mansoni neuropeptide f receptor 76f 0.0203 0.4062 1
Schistosoma mansoni sugar transporter 0.0013 0.0061 0.015
Schistosoma mansoni neuropeptide receptor 0.0203 0.4062 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0023 0.0275 0.0678
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0063 0.1102 0.2714
Brugia malayi Sugar transporter family protein 0.0013 0.0061 0.0061
Echinococcus granulosus glycine receptor subunit beta 0.0053 0.0892 0.2196
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0892 0.2196
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0033 0.0473 0.4969
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0061 0.0347
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0016 0.0038
Brugia malayi photoreceptor-specific nuclear receptor 0.0023 0.0275 0.0275
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0011 0.0007 0.0064
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0892 0.2196
Echinococcus granulosus tm gpcr rhodopsin 0.0203 0.4062 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0203 0.4062 1
Schistosoma mansoni coup transcription factor 0.0023 0.0275 0.0678
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0275 0.0275
Schistosoma mansoni amine GPCR 0.0203 0.4062 1
Echinococcus granulosus chromobox protein 1 0.0063 0.1105 0.2721
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0029 0.0387 0.0954
Echinococcus multilocularis rhodopsin orphan GPCR 0.0203 0.4062 1
Onchocerca volvulus Putative nachr subunit 0.0053 0.0892 0.2196
Schistosoma mansoni hypothetical protein 0.0014 0.0083 0.0204
Entamoeba histolytica protein kinase, putative 0.0029 0.0387 0.3515
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0051 0.0867 1
Brugia malayi PAS domain containing protein 0.0041 0.0644 0.0644
Echinococcus granulosus neuropeptides capa receptor 0.0203 0.4062 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0011 0.0016 0.0016
Schistosoma mansoni nAChR subunit 0.0024 0.0295 0.0726
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0275 0.0678
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0011 0.0016 0.0016
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0029 0.0388 0.0724
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0892 0.2196
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0023 0.0275 0.0678
Leishmania major protein kinase, putative 0.0012 0.0045 0.046
Loa Loa (eye worm) hypothetical protein 0.0027 0.035 0.035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0203 0.4062 1
Echinococcus granulosus serotonin receptor 0.0203 0.4062 1
Loa Loa (eye worm) neuropeptide F receptor 0.0203 0.4062 0.4062
Schistosoma mansoni hypothetical protein 0.0203 0.4062 1
Schistosoma mansoni hypothetical protein 0.0014 0.0074 0.0182
Brugia malayi nuclear receptor RXR 0.0012 0.0043 0.0043
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0094 0.1756 0.4321
Echinococcus multilocularis synaptic vesicle 2 protein 0.0013 0.0061 0.015
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0024 0.0295 0.0295
Brugia malayi larval opioid receptor 0.0203 0.4062 0.4062
Onchocerca volvulus 0.0203 0.4062 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0035 0.0524 0.1291
Schistosoma mansoni amine GPCR 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0107 0.0107
Echinococcus granulosus G protein coupled receptor 139 0.0203 0.4062 1
Brugia malayi hypothetical protein 0.0011 0.0016 0.0016
Brugia malayi neuropeptide F receptor 0.0203 0.4062 0.4062
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0029 0.0387 0.0954
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Echinococcus multilocularis g protein coupled receptor 0.0203 0.4062 1
Trypanosoma brucei glucose transporter 1E 0.0029 0.0395 0.4147
Schistosoma mansoni amine GPCR 0.0203 0.4062 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0023 0.0275 0.0678
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Echinococcus multilocularis neuropeptide receptor A26 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Schistosoma mansoni biogenic amine (5HT) receptor 0.0203 0.4062 1
Onchocerca volvulus 0.0053 0.0892 0.2196
Loa Loa (eye worm) hypothetical protein 0.0028 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.0035 0.0512 0.0512
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0045 0.0729 0.0729
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Leishmania major hypothetical protein, conserved 0.0013 0.0061 0.0628
Mycobacterium ulcerans putative regulatory protein 0.003 0.0421 0.4845
Trypanosoma brucei glucose transporter, putative 0.0029 0.0395 0.4147
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0051 0.0867 0.2133
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0028 0.0375 0.0924
Echinococcus granulosus lysyl tRNA synthetase 0.0021 0.0224 0.0551
Schistosoma mansoni neuropeptide receptor 0.0203 0.4062 1
Echinococcus multilocularis sex peptide receptor 0.0203 0.4062 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0203 0.4062 0.4062
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0203 0.4062 1
Trypanosoma cruzi hexose transporter 0.0029 0.0395 0.4147
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0016
Onchocerca volvulus 0.0013 0.0061 0.015
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0054 0.0916 0.2255
Leishmania major glucose transporter, lmgt3 0.0029 0.0395 0.4147
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0028 0.0381 0.0381
Echinococcus granulosus Nuclear hormone receptor HR96 0.0011 0.0016 0.0038
Schistosoma mansoni nuclear receptor nhr-48 0.0011 0.0016 0.0038
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0023 0.0275 0.0678
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Echinococcus granulosus FTZ F1 alpha 0.0023 0.0275 0.0678
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0023 0.0275 0.0275
Plasmodium falciparum calcium-dependent protein kinase 5 0.0029 0.0388 0.0476
Echinococcus granulosus tachykinin peptides receptor 99D 0.0203 0.4062 1
Echinococcus multilocularis zinc finger protein 0.0018 0.0155 0.0382
Schistosoma mansoni neuropeptide F-like receptor 0.0203 0.4062 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0203 0.4062 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0892 0.0892
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Onchocerca volvulus 0.0013 0.0061 0.015
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0011 0.0007 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0042
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0061 0.0061
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0032 0.0465 0.1145
Schistosoma mansoni opsin-like receptor 0.0203 0.4062 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0203 0.4062 1
Schistosoma mansoni neuropeptide F-like receptor 0.0203 0.4062 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0203 0.4062 0.4062
Plasmodium falciparum protein kinase 6 0.0398 0.8153 1
Schistosoma mansoni hypothetical protein 0.0019 0.0175 0.0431
Schistosoma mansoni nAChR subunit 0.0053 0.0892 0.2196
Schistosoma mansoni lysyl-tRNA synthetase 0.0021 0.0224 0.0551
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0151 0.297 0.3643
Onchocerca volvulus 0.0013 0.0061 0.015
Brugia malayi AKH receptor 0.0203 0.4062 0.4062
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Plasmodium falciparum mitogen-activated protein kinase 2 0.0151 0.297 0.3643
Trypanosoma cruzi ISWI complex protein 0.0014 0.0074 0.0764
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0011 0.0007 0.0042
Brugia malayi Tachykinin-like peptides receptor 99D 0.0203 0.4062 0.4062
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0203 0.4062 1
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Brugia malayi hypothetical protein 0.0024 0.0295 0.0295
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0033 0.0473 0.4969
Echinococcus granulosus orexin receptor type 2 0.0203 0.4062 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0056 0.0951 1
Brugia malayi Bromodomain containing protein 0.0035 0.051 0.051
Echinococcus granulosus 7tm_1 domain containing protein 0.0203 0.4062 1
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0053 0.0892 0.0892
Loa Loa (eye worm) hypothetical protein 0.0021 0.0224 0.0224
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0023 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0023 0.0264 0.0264
Schistosoma mansoni sugar transporter 0.0013 0.0061 0.015
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0275 0.0678
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Echinococcus granulosus neuropeptide s receptor 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0381 0.0381
Brugia malayi sulfakinin receptor protein 0.0203 0.4062 0.4062
Schistosoma mansoni neuropeptide receptor 0.0203 0.4062 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0892 0.0892
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0892 0.0892
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0203 0.4062 1
Echinococcus multilocularis calcium dependent protein kinase 0.0027 0.035 0.0862
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0011 0.0007 0.0042
Brugia malayi Dopamine receptor 0.0203 0.4062 0.4062
Brugia malayi Nuclear hormone receptor E75 0.0011 0.0016 0.0016
Brugia malayi Uncoordinated protein 44 0.0012 0.0038 0.0038
Echinococcus granulosus nuclear receptor nhr 48 0.0011 0.0016 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0203 0.4062 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0892 0.2196
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0581 0.143
Brugia malayi hypothetical protein 0.0013 0.0061 0.0061
Onchocerca volvulus 0.0203 0.4062 1
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0051 0.0867 0.0867
Schistosoma mansoni nuclear receptor 0.0011 0.0016 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0023 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Plasmodium vivax hexose transporter 0.0094 0.1756 0.2153
Echinococcus granulosus chromobox protein 1 0.0063 0.1105 0.2721
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0028 0.0375 0.0924
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0011 0.0016 0.0038
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0062 0.1086 0.2674
Echinococcus granulosus solute carrier family 22 0.0013 0.0061 0.015
Echinococcus multilocularis Chromobox protein 3 0.001 0.000000014744 0.000000036293
Brugia malayi excitatory GABA receptor EXP-1A 0.0053 0.0892 0.0892
Echinococcus granulosus dro:myosuppressin receptor 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0203 0.4062 1
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0056 0.0951 0.2342
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0275 0.0275
Schistosoma mansoni nAChR subunit 0.0053 0.0892 0.2196
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0053 0.0892 0.2196
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0029 0.0387 0.0387
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0203 0.4062 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0023 0.0275 0.0275
Brugia malayi G-protein coupled receptor 0.0203 0.4062 0.4062
Trypanosoma brucei THT1 - hexose transporter, putative 0.0029 0.0395 0.4147
Giardia lamblia Lysyl-tRNA synthetase 0.0021 0.0224 0.5182
Brugia malayi nuclear receptor RXR 0.0011 0.0016 0.0016
Onchocerca volvulus 0.0203 0.4062 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0023 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0275 0.0678
Onchocerca volvulus 0.0013 0.0061 0.015
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0013 0.0061 0.0628
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0275 0.0678
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Schistosoma mansoni hypothetical protein 0.0094 0.1756 0.4321
Onchocerca volvulus 0.003 0.0421 0.1035
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0029 0.0387 0.0954
Echinococcus granulosus nAChR subunit 0.0028 0.0381 0.0937
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Loa Loa (eye worm) hypothetical protein 0.0014 0.0083 0.0083
Onchocerca volvulus 0.0013 0.0061 0.015
Brugia malayi Cytochrome P450 family protein 0.001 0.0001 0.0001
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0203 0.4062 1
Onchocerca volvulus 0.0203 0.4062 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0023 0.0275 0.0678
Loa Loa (eye worm) hypothetical protein 0.0012 0.0043 0.0043
Trichomonas vaginalis sugar transport protein, putative 0.0013 0.0061 0.0347
Loa Loa (eye worm) hypothetical protein 0.0023 0.0275 0.0275
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0496 0.1221
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Schistosoma mansoni amine GPCR 0.0203 0.4062 1
Echinococcus multilocularis neuropeptide Y receptor 0.0203 0.4062 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0014 0.0083 0.0204
Onchocerca volvulus 0.0011 0.0016 0.0038
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0029 0.0388 0.0724
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0023 0.0275 0.0678
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0012 0.0043 0.0043
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0094 0.1756 0.4321
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0203 0.4062 0.4062
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0053 0.0892 0.2196
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0023 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0038
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0043 0.0107
Brugia malayi hypothetical protein 0.0013 0.0061 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0203 0.4062 1
Loa Loa (eye worm) nuclear hormone receptor 0.0011 0.0016 0.0016
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Echinococcus granulosus single minded 2 0.0033 0.048 0.1183
Echinococcus multilocularis g-protein coupled receptor 0.0203 0.4062 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0203 0.4062 1
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0151 0.297 0.5546
Loa Loa (eye worm) G-protein coupled receptor 0.0203 0.4062 0.4062
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Brugia malayi Cation transporter family protein 0.0053 0.0892 0.0892
Echinococcus granulosus biogenic amine 5HT receptor 0.0203 0.4062 1
Echinococcus multilocularis GPCR, family 2 0.0014 0.0083 0.0204
Schistosoma mansoni biogenic amine receptor 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Brugia malayi Serotonin receptor 0.0203 0.4062 0.4062
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0203 0.4062 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0892 0.0892
Echinococcus multilocularis neuropeptide receptor 0.0203 0.4062 1
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Brugia malayi G protein-coupled receptor 0.0203 0.4062 0.4062
Schistosoma mansoni zinc finger protein 0.0011 0.0016 0.0038
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0295 0.0295
Echinococcus granulosus tm gpcr rhodopsin 0.0203 0.4062 1
Trypanosoma brucei glucose transporter, putative 0.0029 0.0395 0.4147
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0043 0.0043
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0033 0.0473 0.0884
Schistosoma mansoni bromodomain containing protein 0.0057 0.0984 0.2422
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0053 0.0892 0.0892
Echinococcus granulosus neuropeptide receptor 0.0203 0.4062 1
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0021 0.0224 0.5884
Schistosoma mansoni hypothetical protein 0.0014 0.0083 0.0204
Echinococcus multilocularis solute carrier family 22 0.0013 0.0061 0.015
Echinococcus multilocularis allatostatin A receptor 0.0203 0.4062 1
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0395 0.2251
Echinococcus multilocularis rhodopsin orphan GPCR 0.0203 0.4062 1
Schistosoma mansoni protein kinase 0.0029 0.0387 0.0954
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0295 0.0726
Echinococcus multilocularis solute carrier family 22 0.0013 0.0061 0.015
Loa Loa (eye worm) hypoxia-induced factor 1 0.0127 0.2447 0.2447
Echinococcus granulosus rhodopsin orphan GPCR 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0056 0.0951 0.0951
Schistosoma mansoni biogenic amine receptor 0.0203 0.4062 1
Onchocerca volvulus 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Onchocerca volvulus 0.0203 0.4062 1
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Schistosoma mansoni neuropeptide receptor 0.0203 0.4062 1
Plasmodium falciparum calcium-dependent protein kinase 4 0.0029 0.0388 0.0476
Brugia malayi putative neuropeptide receptor 0.0203 0.4062 0.4062
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0308 0.1756
Onchocerca volvulus 0.0023 0.0275 0.0678
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0016
Entamoeba histolytica hypothetical protein 0.0063 0.1102 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.0014 0.0083 0.0204
Plasmodium vivax calcium-dependent protein kinase, putative 0.0029 0.0388 0.0476
Echinococcus multilocularis serotonin receptor 0.0203 0.4062 1
Trypanosoma brucei glucose transporter, putative 0.0029 0.0395 0.4147
Brugia malayi Sugar transporter family protein 0.0013 0.0061 0.0061
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0029 0.0387 0.0954
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Onchocerca volvulus 0.0013 0.0061 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0524 0.2988
Echinococcus granulosus fmrfamide receptor 0.0203 0.4062 1
Toxoplasma gondii sugar transporter ST3 0.0013 0.0061 0.0114
Schistosoma mansoni chromobox protein 0.0063 0.1105 0.2721
Echinococcus granulosus solute carrier family 22 0.0013 0.0061 0.015
Brugia malayi nuclear hormone receptor 0.0023 0.0275 0.0275
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0029 0.0388 0.0724
Echinococcus multilocularis nAChR subunit 0.0053 0.0892 0.2196
Echinococcus multilocularis chromobox protein 1 0.0063 0.1105 0.2721
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0051 0.0867 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Echinococcus granulosus synaptic vesicle 2 protein 0.0013 0.0061 0.015
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0056 0.0951 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0203 0.4062 1
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0011 0.0007 0.0042
Chlamydia trachomatis lysine--tRNA ligase 0.0021 0.0224 1
Onchocerca volvulus 0.0203 0.4062 1
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0021 0.0224 0.2572
Loa Loa (eye worm) hypothetical protein 0.0012 0.0043 0.0043
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0023 0.0275 0.0678
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Echinococcus granulosus GPCR family 2 0.0014 0.0083 0.0204
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0029 0.0387 0.0387
Loa Loa (eye worm) hypothetical protein 0.0012 0.0043 0.0043
Schistosoma mansoni acetylcholine receptor-related 0.0024 0.0295 0.0726
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0053 0.0892 0.2196
Brugia malayi chromobox protein homolog 3 0.0035 0.0524 0.0524
Loa Loa (eye worm) hypothetical protein 0.0023 0.0275 0.0275
Trypanosoma brucei glucose transporter, putative 0.0029 0.0395 0.4147
Loa Loa (eye worm) hypothetical protein 0.0028 0.0375 0.0375
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0011 0.0016 0.0038
Echinococcus granulosus aryl hydrocarbon receptor 0.0011 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Plasmodium falciparum calcium-dependent protein kinase 1 0.0029 0.0388 0.0476
Brugia malayi nuclear hormone receptor family member odr-7 0.0011 0.0016 0.0016
Echinococcus multilocularis thyroid hormone receptor alpha 0.0023 0.0275 0.0678
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0203 0.4062 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0892 0.0892
Trypanosoma cruzi glucose transporter, putative 0.0013 0.0061 0.0628
Schistosoma mansoni nAChR subunit 0.0053 0.0892 0.2196
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0023 0.0275 0.0275
Brugia malayi bHLH-PAS transcription factor 0.003 0.0421 0.0421
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0024 0.0295 0.0295
Schistosoma mansoni nuclear receptor 0.0011 0.0016 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0395 0.2251
Brugia malayi PHD-finger family protein 0.0022 0.0256 0.0256
Brugia malayi nuclear hormone receptor family member nhr-6 0.0011 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Loa Loa (eye worm) hypothetical protein 0.0023 0.0275 0.0275
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0024 0.0295 0.0726
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0023 0.0275 0.0275
Echinococcus granulosus solute carrier family 22 0.0013 0.0061 0.015
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0023 0.0275 0.0678
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0892 0.0892
Schistosoma mansoni sugar transporter 0.0013 0.0061 0.015
Echinococcus multilocularis transcription factor Dp 1 0.0032 0.046 0.1131
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0203 0.4062 1
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Echinococcus granulosus rhodopsin orphan GPCR 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Echinococcus multilocularis neuropeptide Y receptor 0.0203 0.4062 1
Trichomonas vaginalis chromobox protein, putative 0.0063 0.1105 0.6296
Echinococcus multilocularis somatostatin receptor 0.0203 0.4062 1
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0053 0.0892 0.2196
Onchocerca volvulus 0.0028 0.0381 0.0937
Loa Loa (eye worm) LGC-31 protein 0.0053 0.0892 0.0892
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0029 0.0387 0.0954
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0053 0.0892 0.2196
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0053 0.0892 0.2196
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0029 0.0387 0.0954
Entamoeba histolytica hypothetical protein 0.0063 0.1102 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0203 0.4062 1
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Toxoplasma gondii protein kinase, putative 0.0265 0.5355 1
Entamoeba histolytica hypothetical protein 0.0063 0.1102 1
Leishmania major protein kinase, putative 0.0017 0.0131 0.1367
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0011 0.0016 0.0038
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Brugia malayi hypothetical protein 0.0024 0.0295 0.0295
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0018 0.0157 0.4081
Echinococcus multilocularis solute carrier family 22 0.0013 0.0061 0.015
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Brugia malayi G-protein coupled receptor 0.0203 0.4062 0.4062
Echinococcus granulosus allatostatin A receptor 0.0203 0.4062 1
Onchocerca volvulus 0.0013 0.0061 0.015
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0051 0.0867 0.9109
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0029 0.0388 0.0476
Loa Loa (eye worm) hypothetical protein 0.0023 0.0275 0.0275
Schistosoma mansoni myosin xvIII 0.0203 0.4062 1
Brugia malayi Melatonin receptor type 1A 0.0203 0.4062 0.4062
Brugia malayi hypothetical protein 0.0011 0.0016 0.0016
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0007 0.0042
Echinococcus granulosus calcium dependent protein kinase 0.0027 0.035 0.0862
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0011 0.0007 0.0007
Brugia malayi hypothetical protein 0.0012 0.0043 0.0043
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0021 0.0224 0.2572
Loa Loa (eye worm) hypothetical protein 0.0045 0.0729 0.0729
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Loa Loa (eye worm) ACC-1 protein 0.0053 0.0892 0.0892
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0011 0.0016 0.0038
Loa Loa (eye worm) hypothetical protein 0.0028 0.0375 0.0375
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0012 0.0043 0.0107
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0053 0.0892 0.2196
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0023 0.0275 0.0275
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0013 0.0061 0.069
Brugia malayi GnHR receptor homolog 0.0203 0.4062 0.4062
Plasmodium falciparum hexose transporter 0.0094 0.1756 0.2153
Onchocerca volvulus 0.0203 0.4062 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0381 0.0381
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Echinococcus granulosus rhodopsin orphan GPCR 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0029 0.0388 0.0476
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0053 0.0892 0.0892
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0203 0.4062 1
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0007 0.0042
Brugia malayi Protein kinase domain containing protein 0.0014 0.0076 0.0076
Plasmodium falciparum protein kinase 7 0.0265 0.5355 0.6568
Echinococcus multilocularis solute carrier family 22 0.0013 0.0061 0.015
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0203 0.4062 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0029 0.0387 0.0954
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0203 0.4062 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0275 0.0275
Loa Loa (eye worm) acetylcholine receptor protein 0.0024 0.0295 0.0295
Plasmodium falciparum lysine--tRNA ligase 0.0021 0.0224 0.0275
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0028 0.0375 0.0924
Echinococcus granulosus glycine receptor subunit beta 0.0053 0.0892 0.2196
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0053 0.0892 0.2196
Echinococcus granulosus ecdysone induced protein 78C 0.0023 0.0275 0.0678
Loa Loa (eye worm) hypothetical protein 0.0038 0.0593 0.0593
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0094 0.1756 0.4321
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0094 0.1756 0.4321
Trypanosoma brucei THT1 - hexose transporter, putative 0.0029 0.0395 0.4147
Schistosoma mansoni zinc finger protein 0.0014 0.0074 0.0182
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0203 0.4062 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0023 0.0275 0.0275
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Trichomonas vaginalis chromobox protein, putative 0.0038 0.0581 0.3308
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0056 0.0951 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0053 0.0892 0.2196
Echinococcus multilocularis neuropeptide s receptor 0.0203 0.4062 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0524 0.0524
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0275 0.0678
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0203 0.4062 0.4062
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0031 0.0436 0.0436
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0061 0.0347
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0042
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0018 0.017 0.0966
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0012 0.0036 0.0089
Schistosoma mansoni nAChR subunit 0.0053 0.0892 0.2196
Loa Loa (eye worm) sugar transporter 0.0094 0.1756 0.1756
Echinococcus multilocularis netrin receptor unc 5 0.0012 0.0038 0.0094
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0014 0.0083 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0203 0.4062 1
Echinococcus granulosus zinc finger protein 0.0018 0.0155 0.0382
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0023 0.0275 0.0678
Schistosoma mansoni lysyl-tRNA synthetase 0.0021 0.0224 0.0551
Schistosoma mansoni protein kinase 0.0029 0.0387 0.0954
Echinococcus multilocularis neuropeptide FF receptor 2 0.0203 0.4062 1
Trypanosoma brucei ISWI complex protein 0.0014 0.0074 0.0764
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0395 0.2251
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0016
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0056 0.0951 0.2342
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Brugia malayi neuropeptide F receptor 0.0203 0.4062 0.4062
Loa Loa (eye worm) TYRA-2 protein 0.0203 0.4062 0.4062
Leishmania major glucose transporter/membrane transporter D2, putative 0.0029 0.0395 0.4147
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Trypanosoma cruzi sugar transporter, putative 0.0013 0.0061 0.0628
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Echinococcus multilocularis nuclear receptor nhr 48 0.0011 0.0016 0.0038
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Brugia malayi hypothetical protein 0.0203 0.4062 0.4062
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0203 0.4062 1
Onchocerca volvulus 0.0053 0.0892 0.2196
Brugia malayi hypothetical protein 0.0063 0.1102 0.1102
Brugia malayi hypothetical protein 0.0203 0.4062 0.4062
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0024 0.0295 0.0295
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0203 0.4062 1
Onchocerca volvulus 0.0203 0.4062 1
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0033 0.0473 0.4969
Brugia malayi hypothetical protein 0.0137 0.267 0.267
Schistosoma mansoni nAChR subunit 0.0053 0.0892 0.2196
Brugia malayi ecdysteroid receptor 0.0023 0.0275 0.0275
Onchocerca volvulus 0.0203 0.4062 1
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0011 0.0007 0.0042
Schistosoma mansoni nAChR subunit 0.0053 0.0892 0.2196
Brugia malayi CHD4 protein 0.0012 0.0036 0.0036
Schistosoma mansoni ankyrin 23/unc44 0.0012 0.0038 0.0094
Onchocerca volvulus 0.0013 0.0061 0.015
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0203 0.4062 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0033 0.0473 0.4969
Toxoplasma gondii sugar transporter ST2 0.0013 0.0061 0.0114
Schistosoma mansoni nAChR subunit 0.0024 0.0295 0.0726
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0016
Echinococcus multilocularis fmrfamide receptor 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0024 0.0295 0.0726
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0012 0.0038 0.0094
Schistosoma mansoni growth hormone secretagogue receptor 0.0203 0.4062 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0012 0.004 0.0099
Leishmania major lysyl-tRNA synthetase, putative 0.0021 0.0224 0.2343
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0892 0.2196
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0203 0.4062 0.4062
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0524 0.2988
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0203 0.4062 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0015 0.0107 0.0264
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0054 0.0916 0.2255
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0023 0.0275 0.0678
Loa Loa (eye worm) neuropeptide F receptor 0.0203 0.4062 0.4062
Onchocerca volvulus 0.0013 0.0061 0.015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0016
Echinococcus multilocularis serotonin receptor 0.0203 0.4062 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0031 0.0436 0.1074
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0203 0.4062 1
Schistosoma mansoni acetylcholine receptor subunit beta 0.0024 0.0295 0.0726
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0011 0.0007 0.0064
Schistosoma mansoni retinoic acid receptor RXR 0.0023 0.0275 0.0678
Schistosoma mansoni zinc finger protein 0.0018 0.0155 0.0382
Brugia malayi nuclear hormone receptor 0.0011 0.0016 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0203 0.4062 1
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0061 0.0114
Echinococcus granulosus g-protein coupled receptor 0.0203 0.4062 1
Brugia malayi Latrophilin receptor protein 2 0.0014 0.0083 0.0083
Toxoplasma gondii lysine-tRNA ligase 0.0021 0.0224 0.0418
Loa Loa (eye worm) cytochrome P450 family protein 0.001 0.0001 0.0001
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0061 0.0061
Schistosoma mansoni chromobox protein 0.0063 0.1105 0.2721
Echinococcus granulosus Chromobox protein 3 0.001 0.000000014744 0.000000036293
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0028 0.0375 0.2138
Schistosoma mansoni opsin-like receptor 0.0203 0.4062 1
Brugia malayi hypothetical protein 0.0024 0.0295 0.0295
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0053 0.0892 0.2196
Schistosoma mansoni RAR-like nuclear receptor 0.0023 0.0275 0.0678
Echinococcus multilocularis G protein coupled receptor 139 0.0203 0.4062 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0275 0.0678
Brugia malayi steroid hormone receptor 0.0023 0.0275 0.0275
Schistosoma mansoni glucose transport protein 0.0094 0.1756 0.4321
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0024 0.0295 0.0726
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Echinococcus granulosus Nuclear hormone receptor HR96 0.0011 0.0016 0.0038
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0051 0.0867 0.2133
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0295 0.0295
Schistosoma mansoni aryl hydrocarbon receptor 0.0041 0.0644 0.1586
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Onchocerca volvulus 0.0053 0.0892 0.2196
Brugia malayi Cytochrome P450 family protein 0.001 0.0001 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Echinococcus multilocularis glycine receptor subunit beta 0.0053 0.0892 0.2196
Loa Loa (eye worm) hypothetical protein 0.0028 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Loa Loa (eye worm) hypothetical protein 0.0023 0.0275 0.0275
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0012 0.0038 0.0038
Brugia malayi Heterochromatin protein 1 0.0063 0.1105 0.1105
Echinococcus granulosus neuropeptide Y receptor 0.0203 0.4062 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0016 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0203 0.4062 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0295 0.0295
Brugia malayi hypothetical protein 0.0203 0.4062 0.4062
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0203 0.4062 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0892 0.0892
Loa Loa (eye worm) hypothetical protein 0.0012 0.0043 0.0043
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0275 0.0678
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0028 0.0375 0.0375
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0011 0.0007 0.0042
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0029 0.0393 0.224
Echinococcus granulosus g protein coupled receptor 0.0203 0.4062 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0011 0.0016 0.0016
Trypanosoma brucei sugar transporter, putative 0.0013 0.0061 0.0628
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0028 0.0381 0.0381
Schistosoma mansoni biogenic amine receptor 0.0203 0.4062 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0038 0.0038
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0053 0.0892 0.2196
Onchocerca volvulus 0.0011 0.0007 0.0018
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0053 0.0892 0.0892
Onchocerca volvulus 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0016 0.0038
Brugia malayi hypothetical protein 0.0203 0.4062 0.4062
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0053 0.0892 0.0892
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Trichomonas vaginalis chromobox protein, putative 0.0038 0.0581 0.3308
Loa Loa (eye worm) hypothetical protein 0.0137 0.267 0.267
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0011 0.0007 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0275 0.0275
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0395 0.4147
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0094 0.1756 0.4321
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0203 0.4062 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0023 0.0275 0.0678
Echinococcus granulosus nAChR subunit 0.0053 0.0892 0.2196
Brugia malayi Dopamine receptor protein 1 0.0203 0.4062 0.4062
Echinococcus granulosus transcription factor Dp 1 0.0032 0.046 0.1131
Loa Loa (eye worm) hypothetical protein 0.0028 0.0381 0.0381
Onchocerca volvulus 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0203 0.4062 0.4062
Brugia malayi conserved hypotetical protein 0.0011 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0014 0.0083 0.0204
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0053 0.0892 0.2196
Leishmania major hypothetical protein, conserved 0.0014 0.0074 0.0764
Giardia lamblia Prolyl-tRNA synthetase 0.0028 0.0375 1
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Echinococcus granulosus Sugar transporter ERD6 protein 0.0013 0.0061 0.015
Loa Loa (eye worm) sugar transporter 0.0013 0.0061 0.0061
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0203 0.4062 1
Mycobacterium ulcerans sugar transporter 0.0013 0.0061 0.069
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0053 0.0892 0.0892
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0051 0.0867 0.2133
Plasmodium vivax proline--tRNA ligase, putative 0.0033 0.0473 0.0581
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0053 0.0892 0.0892
Schistosoma mansoni hypothetical protein 0.0031 0.043 0.1059
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0056 0.0951 1
Brugia malayi ORL1-like opioid receptor 0.0203 0.4062 0.4062
Brugia malayi follicle stimulating hormone receptor 0.0203 0.4062 0.4062
Schistosoma mansoni hypothetical protein 0.0203 0.4062 1
Brugia malayi Serotonin receptor 0.0203 0.4062 0.4062
Echinococcus granulosus nuclear factor of activated T cells 5 0.0062 0.1086 0.2674
Trichomonas vaginalis CAMK family protein kinase 0.0029 0.0387 0.2207
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0061 0.0347
Echinococcus granulosus 7TM GPCR rhodopsin 0.0203 0.4062 1
Schistosoma mansoni hypothetical protein 0.0203 0.4062 1
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0029 0.0393 0.224
Onchocerca volvulus Putative transporter 0.0013 0.0061 0.015
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0203 0.4062 1
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0275 0.0678
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0024 0.0295 0.0726
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0024 0.0295 0.0295
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0053 0.0892 0.2196
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0892 0.2196
Onchocerca volvulus 0.0053 0.0892 0.2196
Schistosoma mansoni histamine h1 receptor 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0029 0.0387 0.0387
Echinococcus multilocularis rhodopsin orphan GPCR 0.0203 0.4062 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0892 0.0892
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0013 0.0061 0.069
Echinococcus multilocularis General substrate transporter 0.0081 0.1478 0.3639
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0013 0.0061 0.5
Brugia malayi nuclear receptor NHR-67 0.0011 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0012 0.0045 0.046
Leishmania major glucose transporter, lmgt2 0.0029 0.0395 0.4147
Echinococcus granulosus fetal alzheimer antigen falz 0.002 0.0211 0.052
Echinococcus granulosus rhodopsin orphan GPCR 0.0203 0.4062 1
Echinococcus granulosus tm gpcr rhodopsin 0.0203 0.4062 1
Schistosoma mansoni neurotransmitter gated ion channel 0.0028 0.0381 0.0937
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0053 0.0892 0.0892
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0053 0.0892 0.0892
Loa Loa (eye worm) ACC-1 protein 0.0053 0.0892 0.0892
Onchocerca volvulus 0.0024 0.0295 0.0726
Echinococcus granulosus General substrate transporter 0.0081 0.1478 0.3639
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0203 0.4062 0.4062
Brugia malayi hypothetical protein 0.0203 0.4062 0.4062
Loa Loa (eye worm) hypothetical protein 0.0012 0.0043 0.0043
Loa Loa (eye worm) steroid hormone receptor 0.0023 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0016
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0012 0.0043 0.0107
Echinococcus granulosus neuropeptide receptor 0.0203 0.4062 1
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0028 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0016 0.0038
Onchocerca volvulus Neuropeptide F receptor homolog 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Trichomonas vaginalis glucose transporter, putative 0.0013 0.0061 0.0347
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0053 0.0892 0.2196
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0061 0.0061
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0024 0.0295 0.0295
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0061
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0094 0.1756 0.4321
Trypanosoma brucei glucose transporter, putative 0.0029 0.0395 0.4147
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0016
Echinococcus granulosus hypothetical protein 0.0203 0.4062 1
Loa Loa (eye worm) CYP4Cod1 0.001 0.0001 0.0001
Onchocerca volvulus 0.0203 0.4062 1
Onchocerca volvulus 0.0203 0.4062 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0023 0.0275 0.0678
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0295 0.0726
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Trypanosoma brucei glucose transporter 2A 0.0029 0.0395 0.4147
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0014 0.0083 0.0204
Brugia malayi Bromodomain containing protein 0.0068 0.1206 0.1206
Trichomonas vaginalis chromobox protein, putative 0.0063 0.1105 0.6296
Echinococcus multilocularis g protein coupled receptor 0.0203 0.4062 1
Echinococcus multilocularis glycine receptor subunit beta 0.0053 0.0892 0.2196
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0031 0.0436 0.0436
Schistosoma mansoni netrin receptor unc5 0.0012 0.0038 0.0094
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0028 0.0375 0.3404
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Schistosoma mansoni amine GPCR 0.0203 0.4062 1
Loa Loa (eye worm) bromodomain containing protein 0.0016 0.0119 0.0119
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0203 0.4062 1
Echinococcus multilocularis chromobox protein 1 0.0063 0.1105 0.2721
Echinococcus granulosus peptide allatostatin:somatostatin 0.0203 0.4062 1
Loa Loa (eye worm) G-protein coupled receptor 0.0203 0.4062 0.4062
Echinococcus multilocularis neuropeptides capa receptor 0.0203 0.4062 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0015 0.0107 0.0264
Onchocerca volvulus 0.001 0.000000014744 0.000000036293
Loa Loa (eye worm) hypothetical protein 0.0031 0.043 0.043
Onchocerca volvulus 0.0013 0.0061 0.015
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0013 0.0061 0.0075
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0203 0.4062 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0203 0.4062 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0203 0.4062 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0203 0.4062 1
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0028 0.0381 0.0937
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0308 0.1756
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Loa Loa (eye worm) hypothetical protein 0.0037 0.0556 0.0556
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0094 0.1756 0.4321
Leishmania major protein kinase, putative 0.0029 0.0387 0.4065
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0023 0.0275 0.0678
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0012 0.0043 0.0107
Loa Loa (eye worm) hypothetical protein 0.0028 0.0381 0.0381
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0395 0.4147
Echinococcus granulosus thyroid hormone receptor alpha 0.0011 0.0016 0.0038
Echinococcus multilocularis g protein coupled receptor 0.0203 0.4062 1
Brugia malayi hypoxia-induced factor 1 0.0127 0.2447 0.2447
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Schistosoma mansoni hypothetical protein 0.0063 0.1102 0.2714
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0275 0.0275
Toxoplasma gondii facilitative glucose transporter GT1 0.0094 0.1756 0.3278
Brugia malayi hypothetical protein 0.0024 0.0295 0.0295
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0387 0.0954
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Brugia malayi hypothetical protein 0.0024 0.0295 0.0295
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0023 0.0275 0.0678
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0045 0.073 0.073
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0395 0.2251
Onchocerca volvulus 0.0053 0.0892 0.2196
Brugia malayi Cam kinase protein 1 0.0029 0.0387 0.0387
Trichomonas vaginalis myo-inositol transporter, putative 0.0013 0.0061 0.0347
Brugia malayi orphan nuclear receptor NR2E1 0.0011 0.0016 0.0016
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0892 0.0892
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0053 0.0892 0.2196
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0203 0.4062 1
Echinococcus granulosus netrin receptor unc 5 0.0012 0.0038 0.0094
Schistosoma mansoni adenoreceptor 0.0203 0.4062 1
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0021 0.0224 0.2343
Trypanosoma brucei glucose transporter, putative 0.0029 0.0395 0.4147
Echinococcus multilocularis orexin receptor type 2 0.0203 0.4062 1
Loa Loa (eye worm) GABA receptor subunit 0.0028 0.0381 0.0381
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0015 0.0107 0.0264
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0381 0.0381
Entamoeba histolytica hypothetical protein 0.0028 0.0381 0.3453
Loa Loa (eye worm) PHD-finger family protein 0.0019 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0007
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0011 0.0016 0.0038
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0203 0.4062 1
Entamoeba histolytica hypothetical protein 0.0063 0.1102 1
Loa Loa (eye worm) cytochrome P450 family protein 0.001 0.0001 0.0001
Trypanosoma cruzi hexose transporter, putative 0.0016 0.0118 0.1228
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0012 0.0036 0.0089
Trypanosoma cruzi hexose transporter, putative 0.0013 0.0061 0.0628
Echinococcus multilocularis neuropeptides capa receptor 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0043 0.0043
Onchocerca volvulus 0.0053 0.0892 0.2196
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0203 0.4062 0.4062
Plasmodium falciparum proline--tRNA ligase 0.0033 0.0473 0.0581
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0053 0.0892 0.2196
Brugia malayi nuclear receptor NHR-88 0.0011 0.0016 0.0016
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0011 0.0007 0.0064
Mycobacterium ulcerans integral membrane transport protein 0.0013 0.0061 0.069
Echinococcus granulosus sex peptide receptor 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0295 0.0295
Echinococcus multilocularis nAChR subunit 0.0028 0.0381 0.0937
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Loa Loa (eye worm) hypothetical protein 0.0203 0.4062 0.4062
Onchocerca volvulus 0.0011 0.0016 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0203 0.4062 1
Schistosoma mansoni protein kinase 0.0029 0.0387 0.0954
Brugia malayi lysyl-tRNA synthetase 0.0021 0.0224 0.0224
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0061 0.0347
Echinococcus granulosus alpha 1A adrenergic receptor 0.0203 0.4062 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0015 0.0107 0.0264
Echinococcus granulosus rhodopsin orphan GPCR 0.0203 0.4062 1
Schistosoma mansoni glucose transporter 0.0013 0.0061 0.015
Brugia malayi Calcitonin receptor-like protein seb-1 0.0045 0.0729 0.0729
Brugia malayi Cation transporter family protein 0.0053 0.0892 0.0892
Loa Loa (eye worm) hypothetical protein 0.0028 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.0053 0.0892 0.0892
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0011 0.0016 0.0038
Brugia malayi hypothetical protein 0.001 0.0002 0.0002
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0045 0.0729 0.0729
Echinococcus granulosus neuropeptide Y receptor 0.0203 0.4062 1
Echinococcus granulosus somatostatin receptor 0.0203 0.4062 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0016
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0012 0.0045 0.046

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 0 % Maximum percent potentiation against gamma-aminobutyric acid (GABA) A receptor, alpha 1 ChEMBL. 12408715
Activity (binding) = 0 % Maximum percent potentiation against gamma-aminobutyric acid (GABA) A receptor, alpha 5 ChEMBL. 12408715
Activity (binding) = 0 % Maximum percent potentiation against gamma-aminobutyric acid (GABA) A receptor, alpha 1 ChEMBL. 12408715
Activity (binding) = 0 % Maximum percent potentiation against gamma-aminobutyric acid (GABA) A receptor, alpha 5 ChEMBL. 12408715
Activity (binding) = 35 % Maximum percent potentiation against gamma-aminobutyric acid (GABA) A receptor, alpha 3 ChEMBL. 12408715
Activity (binding) = 35 % Maximum percent potentiation against gamma-aminobutyric acid (GABA) A receptor, alpha 3 ChEMBL. 12408715
Activity (binding) = 44 % Maximum percent potentiation against gamma-aminobutyric acid (GABA) A receptor, alpha 2 ChEMBL. 12408715
Activity (binding) = 44 % Maximum percent potentiation against gamma-aminobutyric acid (GABA) A receptor, alpha 2 ChEMBL. 12408715
EC50 (binding) = 84 nM Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2 ChEMBL. 12408715
EC50 (binding) = 84 nM Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2 ChEMBL. 12408715
EC50 (binding) = 117 nM Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 3 ChEMBL. 12408715
EC50 (binding) = 117 nM Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 3 ChEMBL. 12408715
Ki (functional) = 133 nM Binding affinity was determined by displacement of [3H]-flumazenil from rat cortex homogenates ChEMBL. 12408715
Ki (functional) = 133 nM Binding affinity was determined by displacement of [3H]-flumazenil from rat cortex homogenates ChEMBL. 12408715

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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