Detailed information for compound 269401

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 263.766 | Formula: C14H18ClN3
  • H donors: 1 H acceptors: 0 LogP: 1.85 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1N(CCc2c1cccc2Cl)CC1=NCCN1
  • InChi: 1S/C14H18ClN3/c1-10-11-3-2-4-13(15)12(11)5-8-18(10)9-14-16-6-7-17-14/h2-4,10H,5-9H2,1H3,(H,16,17)
  • InChiKey: QWBYZJWEFABEMU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax glutathione reductase, putative 0.0066 0.0672 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0475 0.1279
Trypanosoma brucei cysteine peptidase C (CPC) 0.0099 0.1161 1
Echinococcus multilocularis cyclin dependent kinase 9 0.0053 0.0475 0.0475
Echinococcus granulosus snurportin 1 0.0305 0.4226 0.4226
Chlamydia trachomatis glutamine binding protein 0.0067 0.0684 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0032 0.0158 0.0203
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0475 0.1279
Brugia malayi Thioredoxin reductase 0.0066 0.0672 0.0866
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0053 0.0475 0.0475
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0037 0.0242 0.0242
Brugia malayi hypothetical protein 0.0317 0.4412 0.5684
Schistosoma mansoni biogenic amine receptor 0.0317 0.4412 0.4412
Brugia malayi Cathepsin L-like precursor 0.0038 0.0255 0.0329
Plasmodium vivax vivapain-3 0.0031 0.0153 0.2273
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Onchocerca volvulus 0.0053 0.0475 0.0865
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0023 0.0028 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.0153 0.1316
Echinococcus granulosus sodium and chloride dependent glycine 0.0032 0.0158 0.0158
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0242 0.0651
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0056 0.0519 0.0519
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0317 0.4412 0.4412
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0031 0.0153 0.0391
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0032 0.0158 0.0158
Echinococcus granulosus cathepsin l cysteine peptidase 0.0053 0.0475 0.0475
Onchocerca volvulus 0.0317 0.4412 1
Loa Loa (eye worm) hypothetical protein 0.0186 0.2461 0.2461
Entamoeba histolytica cysteine protease, putative 0.0031 0.0153 0.157
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0026 0.0076 0.0076
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0317 0.4412 0.4412
Echinococcus multilocularis glutamate receptor 2 0.0072 0.0752 0.0752
Echinococcus granulosus rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Trypanosoma cruzi cysteine peptidase, putative 0.0031 0.0153 0.0391
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Schistosoma mansoni growth hormone secretagogue receptor 0.0317 0.4412 0.4412
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0023 0.0028 0.0244
Entamoeba histolytica cysteine protease, putative 0.0031 0.0153 0.157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0475 0.4095
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0437 0.1175
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0475 0.4095
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0056 0.0519 0.0519
Echinococcus granulosus cathepsin l1 0.0038 0.0255 0.0255
Onchocerca volvulus 0.0317 0.4412 1
Echinococcus granulosus cysteine protease 0.0031 0.0153 0.0153
Brugia malayi jmjC domain containing protein 0.0039 0.0272 0.0351
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0099 0.1161 0.2974
Loa Loa (eye worm) cysteine protease 0.0053 0.0475 0.0475
Loa Loa (eye worm) glutaminase 2 0.0271 0.3718 0.3718
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0317 0.4412 0.5684
Brugia malayi G-protein coupled receptor 0.0317 0.4412 0.5684
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0475 0.1279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0475 0.1279
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0317 0.4412 0.4412
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0032 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0023 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0056 0.0516 0.0516
Toxoplasma gondii cathepsin B 0.0099 0.1161 1
Trypanosoma brucei mitotic cyclin 6 0.0086 0.0973 0.8381
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0317 0.4412 0.4412
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0317 0.4412 0.4412
Echinococcus multilocularis sodium and chloride dependent glycine 0.0032 0.0158 0.0158
Giardia lamblia NADH oxidase lateral transfer candidate 0.0023 0.0028 0.0244
Brugia malayi cell division control protein 2 homolog 0.005 0.0437 0.0563
Loa Loa (eye worm) glutamate receptor 2 0.0042 0.0319 0.0319
Brugia malayi G-protein coupled receptor 0.0317 0.4412 0.5684
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0036 0.0223 0.0223
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0056 0.0519 0.0519
Trypanosoma cruzi cyclin 6, putative 0.0086 0.0973 0.2492
Loa Loa (eye worm) hypothetical protein 0.0049 0.0424 0.0424
Echinococcus granulosus sex peptide receptor 0.0317 0.4412 0.4412
Trypanosoma cruzi cysteine protease, putative 0.0031 0.0153 0.0391
Giardia lamblia Kinase, CMGC CDK 0.005 0.0437 0.3764
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0053 0.0475 0.0475
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0692 1 1
Trichomonas vaginalis cyclin D, putative 0.0036 0.0223 0.06
Loa Loa (eye worm) glutathione reductase 0.0066 0.0672 0.0672
Entamoeba histolytica cysteine protease, putative 0.0031 0.0153 0.157
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0437 0.0437
Plasmodium falciparum importin beta, putative 0.0029 0.0112 0.1671
Echinococcus multilocularis cyclins 0.0036 0.0223 0.0223
Brugia malayi Cyclin, N-terminal domain containing protein 0.0086 0.0973 0.1253
Trichomonas vaginalis cyclins, putative 0.0059 0.0566 0.1523
Brugia malayi Glutamate receptor 1 precursor 0.0084 0.0942 0.1213
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0317 0.4412 0.4412
Echinococcus multilocularis cyclin dependent kinase 1 0.005 0.0437 0.0437
Trypanosoma brucei trypanothione reductase 0.0066 0.0672 0.5788
Leishmania major cathepsin L-like protease 0.0053 0.0475 0.4095
Brugia malayi Cathepsin L-like precursor 0.0053 0.0475 0.0612
Echinococcus granulosus cyclins 0.0036 0.0223 0.0223
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0031 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0158
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0242 0.0553
Trichomonas vaginalis cyclin B, putative 0.0036 0.0223 0.06
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0023 0.0028 0.0244
Echinococcus granulosus hypothetical protein 0.0317 0.4412 0.4412
Onchocerca volvulus 0.0317 0.4412 1
Brugia malayi jmjC domain containing protein 0.0106 0.1271 0.1637
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0317 0.4412 0.4412
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0026 0.0076 0.0076
Toxoplasma gondii cathepsin CPL 0.0053 0.0475 0.4095
Entamoeba histolytica cyclin family protein 0.0036 0.0223 0.2293
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0023 0.0028 0.5
Brugia malayi Cathepsin L-like precursor 0.0053 0.0475 0.0612
Schistosoma mansoni myosin xvIII 0.0317 0.4412 0.4412
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0475 0.4095
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Trypanosoma cruzi trypanothione reductase, putative 0.0023 0.0028 0.0073
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0032 0.0158 0.0158
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0317 0.4412 0.4412
Entamoeba histolytica cysteine protease, putative 0.0031 0.0153 0.157
Brugia malayi Serotonin receptor 0.0317 0.4412 0.5684
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0475 0.4095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0475 0.1279
Echinococcus granulosus neuropeptide Y receptor 0.0317 0.4412 0.4412
Giardia lamblia PHD finger protein 15 0.0032 0.0171 0.147
Brugia malayi hypothetical protein 0.0317 0.4412 0.5684
Onchocerca volvulus 0.0053 0.0475 0.0865
Onchocerca volvulus Alhambra homolog 0.0032 0.0171 0.0158
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Echinococcus granulosus neuropeptide Y receptor 0.0317 0.4412 0.4412
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0053 0.0475 0.0475
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0032 0.0158 0.0158
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0027 0.0095 0.0095
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0023 0.0028 0.0037
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0028 0.0073
Echinococcus multilocularis neuropeptide s receptor 0.0317 0.4412 0.4412
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.4412 0.4412
Brugia malayi PHD-finger family protein 0.0032 0.0171 0.022
Trypanosoma cruzi cyclin, putative 0.0086 0.0973 0.2492
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0093 0.1073 0.1073
Echinococcus multilocularis cyclin dependent kinase 0.005 0.0437 0.0437
Echinococcus multilocularis cyclins 0.0036 0.0223 0.0223
Schistosoma mansoni adenoreceptor 0.0317 0.4412 0.4412
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0053 0.0475 0.0475
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0317 0.4412 0.4412
Schistosoma mansoni hypothetical protein 0.0026 0.0076 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0475 0.1279
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Onchocerca volvulus 0.0317 0.4412 1
Schistosoma mansoni glutamate receptor kainate 0.0042 0.0319 0.0319
Loa Loa (eye worm) neuropeptide F receptor 0.0317 0.4412 0.4412
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0255 0.0687
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0283 0.3904 0.3904
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0112 0.0967
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0475 0.0475
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0098 0.1141 0.1141
Trichomonas vaginalis cyclins, putative 0.0036 0.0223 0.06
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0475 0.1279
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0026 0.0076 0.0076
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0317 0.4412 0.4412
Schistosoma mansoni neuropeptide F-like receptor 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0171 0.0171
Plasmodium falciparum cysteine proteinase falcipain 3 0.0053 0.0475 0.7075
Schistosoma mansoni hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Brugia malayi hypothetical protein 0.0317 0.4412 0.5684
Schistosoma mansoni amine GPCR 0.0317 0.4412 0.4412
Mycobacterium tuberculosis Probable oxidoreductase 0.0282 0.389 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0317 0.4412 0.5684
Onchocerca volvulus 0.0032 0.0158 0.0128
Echinococcus granulosus G protein coupled receptor 139 0.0317 0.4412 0.4412
Echinococcus multilocularis neuropeptide receptor 0.0317 0.4412 0.4412
Brugia malayi GnHR receptor homolog 0.0317 0.4412 0.5684
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0475 0.4095
Trypanosoma cruzi cyclin, putative 0.0086 0.0973 0.2492
Echinococcus multilocularis neuropeptides capa receptor 0.0317 0.4412 0.4412
Echinococcus granulosus neuropeptide FF receptor 2 0.0317 0.4412 0.4412
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0475 0.1279
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0032 0.0158 0.0158
Trichomonas vaginalis cyclin B, putative 0.0086 0.0973 0.2617
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0032 0.0158 0.0158
Schistosoma mansoni glutamate receptor AMPA 0.0042 0.0319 0.0319
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0242 0.062
Loa Loa (eye worm) hypothetical protein 0.0692 1 1
Schistosoma mansoni importin beta-1 0.0029 0.0112 0.0112
Brugia malayi AKH receptor 0.0317 0.4412 0.5684
Echinococcus granulosus cyclin dependent kinase 0.005 0.0437 0.0437
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0056 0.0519 0.0519
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0317 0.4412 0.4412
Schistosoma mansoni intermediate filament proteins 0.0028 0.0103 0.0103
Giardia lamblia Kinase, CMGC CDK 0.005 0.0437 0.3764
Echinococcus multilocularis G protein coupled receptor 139 0.0317 0.4412 0.4412
Schistosoma mansoni histamine h1 receptor 0.0317 0.4412 0.4412
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0475 0.1279
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0317 0.4412 0.5684
Schistosoma mansoni alpha-1 adrenergic receptor 0.0317 0.4412 0.4412
Brugia malayi Dopamine receptor protein 2 0.0317 0.4412 0.5684
Onchocerca volvulus 0.0317 0.4412 1
Echinococcus multilocularis cathepsin b 0.0283 0.3904 0.3904
Echinococcus multilocularis cyclin dependent kinase 5 0.005 0.0437 0.0437
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Echinococcus granulosus serotonin transporter 0.0186 0.2461 0.2461
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0437 0.0437
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0475 0.1279
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0542 0.7763 0.7763
Leishmania major cathepsin L-like protease 0.0053 0.0475 0.4095
Plasmodium falciparum cyclin 0.0036 0.0223 0.332
Schistosoma mansoni hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Brugia malayi neuropeptide F receptor 0.0317 0.4412 0.5684
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0317 0.4412 0.4412
Entamoeba histolytica cell division protein kinase 2, putative 0.005 0.0437 0.4491
Entamoeba histolytica cysteine proteinase 2 0.0031 0.0153 0.157
Schistosoma mansoni opsin-like receptor 0.0317 0.4412 0.4412
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0032 0.0082
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0032 0.0158 0.136
Onchocerca volvulus 0.0053 0.0475 0.0865
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0475 0.1218
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0032 0.0158 0.0158
Trypanosoma cruzi cysteine proteinase, putative 0.0031 0.0153 0.0391
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.005 0.0437 0.3764
Echinococcus granulosus biogenic amine 5HT receptor 0.0317 0.4412 0.4412
Entamoeba histolytica cysteine proteinase, putative 0.0031 0.0153 0.157
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0242 0.0242
Schistosoma mansoni neuropeptide receptor 0.0317 0.4412 0.4412
Loa Loa (eye worm) neuropeptide F receptor 0.0317 0.4412 0.4412
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0317 0.4412 0.4412
Trichomonas vaginalis cyclin B, putative 0.0086 0.0973 0.2617
Entamoeba histolytica cyclin, putative 0.0036 0.0223 0.2293
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0112 0.0112
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0099 0.1161 1
Echinococcus granulosus neuropeptide receptor 0.0317 0.4412 0.4412
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0171 0.147
Schistosoma mansoni amine GPCR 0.0317 0.4412 0.4412
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.4412 0.4412
Echinococcus multilocularis musashi 0.0028 0.0103 0.0103
Entamoeba histolytica cysteine protease, putative 0.0031 0.0153 0.157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0255 0.0687
Trichomonas vaginalis cyclin B3, putative 0.0036 0.0223 0.06
Echinococcus granulosus glutamate receptor 4 0.0042 0.0309 0.0309
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0317 0.4412 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Plasmodium vivax vivapain-1 0.0031 0.0153 0.2273
Giardia lamblia Cathepsin B precursor 0.0099 0.1161 1
Echinococcus granulosus sodium and chloride dependent glycine 0.0032 0.0158 0.0158
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0317 0.4412 0.4412
Brugia malayi hypothetical protein 0.0317 0.4412 0.5684
Echinococcus granulosus tachykinin peptides receptor 99D 0.0317 0.4412 0.4412
Echinococcus granulosus lamin dm0 0.0028 0.0103 0.0103
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0475 0.1279
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Trichomonas vaginalis cyclin B, putative 0.0086 0.0973 0.2617
Brugia malayi beta-lactamase family protein 0.0037 0.0242 0.0312
Onchocerca volvulus Cathepsin F homolog 0.0053 0.0475 0.0865
Loa Loa (eye worm) fibroinase 0.0053 0.0475 0.0475
Echinococcus granulosus cathepsin l1 0.0053 0.0475 0.0475
Schistosoma mansoni hypothetical protein 0.0317 0.4412 0.4412
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0032 0.0158 0.0158
Brugia malayi hypothetical protein 0.0317 0.4412 0.5684
Schistosoma mansoni cathepsin F (C01 family) 0.0038 0.0255 0.0255
Mycobacterium leprae Probable lipase LipE 0.0037 0.0242 1
Schistosoma mansoni jumonji domain containing protein 0.0085 0.0946 0.0946
Schistosoma mansoni neuropeptide receptor 0.0317 0.4412 0.4412
Brugia malayi Importin beta-1 subunit 0.0029 0.0112 0.0145
Brugia malayi hypothetical protein 0.0317 0.4412 0.5684
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0317 0.4412 0.4412
Onchocerca volvulus 0.0317 0.4412 1
Echinococcus multilocularis cyclins 0.0036 0.0223 0.0223
Echinococcus granulosus cyclin dependent kinase 1 0.005 0.0437 0.0437
Echinococcus granulosus jumonji domain containing protein 0.0045 0.036 0.036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0153 0.0411
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0242 0.0651
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0317 0.4412 0.4412
Entamoeba histolytica cysteine protease, putative 0.0031 0.0153 0.157
Echinococcus granulosus neuropeptide receptor 0.0317 0.4412 0.4412
Trichomonas vaginalis esterase, putative 0.0037 0.0242 0.0651
Echinococcus granulosus neuropeptide receptor A26 0.0317 0.4412 0.4412
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0437 0.1175
Loa Loa (eye worm) hypothetical protein 0.0038 0.0255 0.0255
Schistosoma mansoni biogenic amine (5HT) receptor 0.0317 0.4412 0.4412
Plasmodium falciparum protein kinase 5 0.005 0.0437 0.6503
Brugia malayi follicle stimulating hormone receptor 0.0542 0.7763 1
Schistosoma mansoni glutamate receptor NMDA 0.0042 0.0319 0.0319
Echinococcus multilocularis fmrfamide receptor 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0042 0.0309 0.0309
Brugia malayi glutathione reductase 0.0066 0.0672 0.0866
Loa Loa (eye worm) cathepsin B 0.0099 0.1161 0.1161
Schistosoma mansoni opsin-like receptor 0.0317 0.4412 0.4412
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0238 0.3233 0.8299
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0028 0.0073
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0067 0.0684 0.2696
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0053 0.0475 0.7075
Trichomonas vaginalis cyclins, putative 0.0086 0.0973 0.2617
Plasmodium vivax amine transporter, putative 0.0032 0.0158 0.235
Onchocerca volvulus 0.0317 0.4412 1
Trypanosoma cruzi cruzipain precursor, putative 0.0053 0.0475 0.1218
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0242 0.0553
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0053 0.0475 0.1279
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Brugia malayi Papain family cysteine protease containing protein 0.0031 0.0153 0.0197
Schistosoma mansoni opsin-like receptor 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Echinococcus multilocularis neuropeptide FF receptor 2 0.0317 0.4412 0.4412
Trypanosoma cruzi cdc2-related kinase 1 0.005 0.0437 0.1119
Loa Loa (eye worm) norepinephrine transporter 0.0186 0.2461 0.2461
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.036 0.036
Echinococcus multilocularis g protein coupled receptor 0.0317 0.4412 0.4412
Leishmania major hypothetical protein, conserved 0.0037 0.0242 0.2085
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0032 0.0158 0.136
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.005 0.0437 0.3764
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0023 0.0028 0.0028
Schistosoma mansoni amine GPCR 0.0317 0.4412 0.4412
Leishmania major cathepsin L-like protease 0.0053 0.0475 0.4095
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0067 0.0684 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.4412 0.4412
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.4412 0.4412
Echinococcus multilocularis neuropeptide Y receptor 0.0317 0.4412 0.4412
Brugia malayi beta-lactamase 0.0037 0.0242 0.0312
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0023 0.0028 0.5
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0186 0.2461 0.317
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0475 0.1279
Echinococcus granulosus thioredoxin glutathione reductase 0.0066 0.0672 0.0672
Brugia malayi hypothetical protein 0.0317 0.4412 0.5684
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0112 0.0967
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0475 0.1218
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0099 0.1161 0.3122
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0317 0.4412 0.4412
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.0042 0.0309 0.0309
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0272 0.0272
Brugia malayi hypothetical protein 0.0317 0.4412 0.5684
Mycobacterium ulcerans lipase LipD 0.0037 0.0242 0.0553
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0317 0.4412 0.4412
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0031 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) glutaminase 0.0271 0.3718 0.3718
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0317 0.4412 0.5684
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0171 0.254
Entamoeba histolytica cysteine protease, putative 0.0031 0.0153 0.157
Echinococcus multilocularis g protein coupled receptor 0.0317 0.4412 0.4412
Onchocerca volvulus Neuropeptide F receptor homolog 0.0317 0.4412 1
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0242 0.0553
Brugia malayi Cathepsin L-like precursor 0.0053 0.0475 0.0612
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0475 0.1279
Echinococcus granulosus glutamate receptor 2 0.0098 0.1141 0.1141
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0317 0.4412 0.4412
Schistosoma mansoni biogenic amine receptor 0.0317 0.4412 0.4412
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0042 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0042 0.0309 0.0309
Plasmodium vivax vivapain-2 0.0053 0.0475 0.7075
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Plasmodium vivax vivapain-2 0.0053 0.0475 0.7075
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0023 0.0028 0.0244
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0037 0.0242 0.0242
Loa Loa (eye worm) beta-lactamase 0.0037 0.0242 0.0242
Schistosoma mansoni amine GPCR 0.0317 0.4412 0.4412
Echinococcus multilocularis cyclins 0.0036 0.0223 0.0223
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0036 0.0223 0.0223
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0475 0.1279
Brugia malayi Cathepsin L-like precursor 0.0053 0.0475 0.0612
Leishmania major importin beta-1 subunit, putative 0.0023 0.0032 0.0274
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0023 0.0028 0.0244
Onchocerca volvulus 0.0317 0.4412 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0171 0.0171
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0317 0.4412 0.4412
Plasmodium vivax unspecified product 0.0031 0.0153 0.2273
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0037 0.0242 0.0242
Schistosoma mansoni kinase 0.0053 0.0475 0.0475
Loa Loa (eye worm) serotonin transporter b 0.0186 0.2461 0.2461
Trichomonas vaginalis glutaminase, putative 0.0271 0.3718 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0056 0.0519 0.0519
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0103 0.0132
Leishmania major cathepsin L-like protease 0.0053 0.0475 0.4095
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0028 0.0073
Brugia malayi Cathepsin L-like precursor 0.0053 0.0475 0.0612
Trichomonas vaginalis mercuric reductase, putative 0.0023 0.0028 0.0076
Brugia malayi Protein kinase domain containing protein 0.005 0.0437 0.0563
Onchocerca volvulus 0.0086 0.0973 0.2019
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Brugia malayi Glutamate receptor 2 precursor 0.0084 0.0942 0.1213
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0026 0.0076 0.0076
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0032 0.0086
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0317 0.4412 0.5684
Brugia malayi Melatonin receptor type 1A 0.0317 0.4412 0.5684
Schistosoma mansoni biogenic amine receptor 0.0317 0.4412 0.4412
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0053 0.0475 0.7075
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0283 0.3904 0.3904
Echinococcus multilocularis fmrfamide receptor 0.0317 0.4412 0.4412
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.0153 0.1316
Giardia lamblia Hypothetical protein 0.0036 0.0223 0.1922
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0242 1
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0038 0.0255 0.0255
Onchocerca volvulus 0.0037 0.0242 0.0323
Loa Loa (eye worm) thioredoxin reductase 0.0066 0.0672 0.0672
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0475 0.1279
Entamoeba histolytica cyclin, putative 0.0086 0.0973 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0066 0.0672 0.0672
Mycobacterium ulcerans hypothetical protein 0.0037 0.0242 0.0553
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0032 0.0086
Plasmodium falciparum phd finger protein, putative 0.0032 0.0171 0.254
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Entamoeba histolytica cysteine proteinase 1, putative 0.0031 0.0153 0.157
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0056 0.0519 0.0519
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Schistosoma mansoni glutamate receptor AMPA 0.0042 0.0319 0.0319
Entamoeba histolytica cell division protein kinase 2, putative 0.0059 0.0573 0.5887
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0475 0.4095
Leishmania major trypanothione reductase 0.0066 0.0672 0.5788
Leishmania major cathepsin L-like protease 0.0053 0.0475 0.4095
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0031 0.0153 0.0153
Echinococcus multilocularis neuropeptide receptor A26 0.0317 0.4412 0.4412
Schistosoma mansoni glutamate receptor kainate 0.0042 0.0319 0.0319
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0475 0.4095
Loa Loa (eye worm) hypothetical protein 0.0283 0.3904 0.3904
Brugia malayi ORL1-like opioid receptor 0.0317 0.4412 0.5684
Echinococcus granulosus tm gpcr rhodopsin 0.0317 0.4412 0.4412
Echinococcus granulosus dro:myosuppressin receptor 0.0317 0.4412 0.4412
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0086 0.0973 0.8381
Echinococcus multilocularis orexin receptor type 2 0.0317 0.4412 0.4412
Echinococcus granulosus glutamate receptor 1 0.0042 0.0309 0.0309
Plasmodium falciparum amino acid transporter, putative 0.0032 0.0158 0.235
Echinococcus multilocularis g-protein coupled receptor 0.0317 0.4412 0.4412
Entamoeba histolytica cysteine proteinase, putative 0.0031 0.0153 0.157
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0475 0.1218
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0317 0.4412 0.4412
Echinococcus granulosus neuropeptides capa receptor 0.0317 0.4412 0.4412
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0032 0.0158 0.0158
Echinococcus granulosus cyclin dependent kinase 9 0.0053 0.0475 0.0475
Echinococcus multilocularis nmda type glutamate receptor 0.0093 0.1073 0.1073
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0475 0.1218
Echinococcus granulosus 7tm_1 domain containing protein 0.0317 0.4412 0.4412
Treponema pallidum sodium- and chloride- dependent transporter 0.0186 0.2461 1
Entamoeba histolytica cysteine protease, putative 0.0053 0.0475 0.4887
Echinococcus multilocularis lamin dm0 0.0028 0.0103 0.0103
Brugia malayi sulfakinin receptor protein 0.0317 0.4412 0.5684
Echinococcus granulosus peregrin 0.0032 0.0171 0.0171
Brugia malayi glutaminase DH11.1 0.0271 0.3718 0.479
Brugia malayi Cathepsin L-like precursor 0.0053 0.0475 0.0612
Schistosoma mansoni neuropeptide receptor 0.0317 0.4412 0.4412
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0171 0.0171
Loa Loa (eye worm) cyclin domain-containing protein 0.0036 0.0223 0.0223
Echinococcus multilocularis cathepsin L 0.0031 0.0153 0.0153
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0026 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0038 0.0255 0.0255
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0028 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0475 0.4095
Echinococcus multilocularis sodium and chloride dependent glycine 0.0032 0.0158 0.0158
Entamoeba histolytica cysteine proteinase, putative 0.0031 0.0153 0.157
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Toxoplasma gondii hypothetical protein 0.0027 0.0094 0.0807
Leishmania major cathepsin L-like protease 0.0053 0.0475 0.4095
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0066 0.0672 0.1667
Echinococcus multilocularis allatostatin A receptor 0.0317 0.4412 0.4412
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0158 0.235
Brugia malayi Papain family cysteine protease containing protein 0.0031 0.0153 0.0197
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0305 0.4226 0.4226
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0283 0.3904 0.3904
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0098 0.1141 0.1141
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0171 0.0171
Entamoeba histolytica cysteine protease, putative 0.0031 0.0153 0.157
Mycobacterium tuberculosis Conserved protein 0.0037 0.0242 0.0553
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.005 0.0437 0.0437
Trypanosoma brucei cdc2-related kinase 3 0.005 0.0437 0.3764
Echinococcus granulosus cyclins 0.0036 0.0223 0.0223
Echinococcus multilocularis NMDA receptor 0.0026 0.0076 0.0076
Leishmania major cathepsin L-like protease 0.0053 0.0475 0.4095
Brugia malayi putative neuropeptide receptor NPR1 0.0317 0.4412 0.5684
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0023 0.0028 0.0244
Echinococcus granulosus g protein coupled receptor 0.0317 0.4412 0.4412
Echinococcus granulosus cyclin B3 1 0.0036 0.0223 0.0223
Echinococcus multilocularis cathepsin L cysteine protease 0.0053 0.0475 0.0475
Trichomonas vaginalis cyclins, putative 0.0086 0.0973 0.2617
Giardia lamblia G2/mitotic-specific cyclin B 0.0086 0.0973 0.8381
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0242 0.0312
Schistosoma mansoni ATP-binding cassette transporter 0.0042 0.0319 0.0319
Brugia malayi RNA, U transporter 1 0.0081 0.0896 0.1155
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0475 0.1279
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0242 0.2085
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0038 0.0255 0.0654
Toxoplasma gondii ABC1 family protein 0.0037 0.0242 0.2085
Echinococcus multilocularis G-protein coupled receptor, putative 0.0317 0.4412 0.4412
Echinococcus multilocularis cyclin b3 0.0036 0.0223 0.0223
Brugia malayi RE15519p 0.0317 0.4412 0.5684
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0242 0.0553
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0023 0.0028 0.0422
Onchocerca volvulus 0.0317 0.4412 1
Mycobacterium tuberculosis Conserved protein 0.0037 0.0242 0.0553
Echinococcus multilocularis peregrin 0.0032 0.0171 0.0171
Echinococcus granulosus nmda type glutamate receptor 0.0093 0.1073 0.1073
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0272 0.0272
Brugia malayi G protein-coupled receptor 0.0317 0.4412 0.5684
Echinococcus multilocularis somatostatin receptor 0.0317 0.4412 0.4412
Schistosoma mansoni hypothetical protein 0.0032 0.0171 0.0171
Onchocerca volvulus 0.0317 0.4412 1
Echinococcus granulosus cathepsin L cysteine protease 0.0031 0.0153 0.0153
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0032 0.0158 0.0203
Brugia malayi cathepsin L-like precursor 0.0038 0.0255 0.0329
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0032 0.0158 0.0203
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0158
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0068 0.0698 0.0698
Trichomonas vaginalis cyclin B, putative 0.0086 0.0973 0.2617
Echinococcus granulosus lamin 0.0028 0.0103 0.0103
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0283 0.3904 0.3904
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0242 0.0651
Schistosoma mansoni glutamate receptor kainate 0.0042 0.0319 0.0319
Echinococcus granulosus cathepsin L cysteine proteinase 0.0053 0.0475 0.0475
Onchocerca volvulus 0.0037 0.0242 0.0323
Echinococcus multilocularis lamin 0.0028 0.0103 0.0103
Echinococcus multilocularis cyclin B 0.0086 0.0973 0.0973
Echinococcus granulosus somatostatin receptor 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0186 0.2461 0.2461
Echinococcus granulosus glutamate receptor subunit protein glur 0.0068 0.0698 0.0698
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0242 0.0242
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0242 0.0553
Onchocerca volvulus 0.0053 0.0475 0.0865
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0242 0.0242
Echinococcus multilocularis glutamate receptor 2 0.0098 0.1141 0.1141
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0242 0.0553
Toxoplasma gondii thioredoxin reductase 0.0066 0.0672 0.5788
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0053 0.0475 0.0475
Trypanosoma cruzi cdc2-related kinase 1 0.005 0.0437 0.1119
Toxoplasma gondii hypothetical protein 0.0032 0.0158 0.136
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0475 0.4879
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0475 0.1279
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.005 0.0437 0.0437
Echinococcus granulosus intermediate filament protein 0.0028 0.0103 0.0103
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.1161 0.1161
Leishmania major cysteine peptidase A (CPA) 0.0053 0.0475 0.4095
Loa Loa (eye worm) glutamate receptor 1 0.0084 0.0942 0.0942
Loa Loa (eye worm) hypothetical protein 0.0029 0.0112 0.0112
Echinococcus granulosus cyclins 0.0036 0.0223 0.0223
Echinococcus multilocularis cysteine protease 0.0053 0.0475 0.0475
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0242 0.0242
Plasmodium vivax thioredoxin reductase, putative 0.0066 0.0672 1
Schistosoma mansoni hypothetical protein 0.0317 0.4412 0.4412
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Echinococcus granulosus rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0032 0.0158 0.0158
Trichomonas vaginalis cyclins, putative 0.0086 0.0973 0.2617
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0317 0.4412 0.4412
Echinococcus granulosus cathepsin b 0.0283 0.3904 0.3904
Loa Loa (eye worm) hypothetical protein 0.005 0.0437 0.0437
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.4412 0.4412
Echinococcus multilocularis cyclin dependent kinase 1 0.005 0.0437 0.0437
Echinococcus granulosus glutamate NMDA receptor subunit 0.0042 0.0319 0.0319
Echinococcus granulosus peptide allatostatin:somatostatin 0.0317 0.4412 0.4412
Schistosoma mansoni lamin 0.0028 0.0103 0.0103
Brugia malayi intermediate filament protein 0.0028 0.0103 0.0132
Loa Loa (eye worm) hypothetical protein 0.0053 0.0475 0.0475
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0242 0.0651
Entamoeba histolytica cysteine protease, putative 0.0031 0.0153 0.157
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0242 0.3602
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0067 0.0684 0.2696
Entamoeba histolytica cysteine protease, putative 0.0031 0.0153 0.157
Echinococcus multilocularis neuropeptide Y receptor 0.0317 0.4412 0.4412
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0032 0.0158 0.0158
Schistosoma mansoni cathepsin F (C01 family) 0.0053 0.0475 0.0475
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) solute carrier family 6 member 4 0.0186 0.2461 0.2461
Trypanosoma cruzi cdc2-related kinase 3 0.005 0.0437 0.1119
Echinococcus multilocularis cysteine protease 0.0053 0.0475 0.0475
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0317 0.4412 0.4412
Schistosoma mansoni cyclins 0.0036 0.0223 0.0223
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0317 0.4412 0.4412
Onchocerca volvulus 0.0317 0.4412 1
Schistosoma mansoni glutaminase 0.0271 0.3718 0.3718
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0272 0.0272
Echinococcus multilocularis cyclins 0.0036 0.0223 0.0223
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0028 0.0073
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0103 0.0103
Schistosoma mansoni cathepsin F (C01 family) 0.0053 0.0475 0.0475
Schistosoma mansoni cyclin B3 0.0036 0.0223 0.0223
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0686 0.0686
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0032 0.0158 0.0158
Schistosoma mansoni neuropeptide receptor 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Giardia lamblia Cathepsin B precursor 0.0099 0.1161 1
Mycobacterium ulcerans beta-lactamase 0.0037 0.0242 0.0553
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0475 0.1279
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0032 0.0086
Onchocerca volvulus 0.0032 0.0158 0.0128
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0023 0.0028 0.0244
Toxoplasma gondii NADPH-glutathione reductase 0.0023 0.0028 0.0244
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0475 0.1279
Schistosoma mansoni biogenic amine (5HT) receptor 0.0692 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0475 0.1279
Trypanosoma cruzi cysteine proteinase, putative 0.0031 0.0153 0.0391
Schistosoma mansoni lamin 0.0028 0.0103 0.0103
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0023 0.0028 0.0244
Echinococcus multilocularis g protein coupled receptor 0.0317 0.4412 0.4412
Brugia malayi Cathepsin L-like cysteine proteinase 0.0038 0.0255 0.0329
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.005 0.0437 0.0437
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0032 0.0158 0.1975
Toxoplasma gondii hypothetical protein 0.0032 0.0158 0.136
Onchocerca volvulus Cathepsin L homolog 0.0053 0.0475 0.0865
Loa Loa (eye worm) melatonin receptor type 1A 0.0317 0.4412 0.4412
Onchocerca volvulus 0.0186 0.2461 0.5472
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0317 0.4412 0.4412
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0242 0.062
Echinococcus granulosus 7TM GPCR rhodopsin 0.0317 0.4412 0.4412
Echinococcus multilocularis glutamate receptor 2 0.0084 0.0942 0.0942
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0023 0.0028 0.0422
Onchocerca volvulus Cathepsin L homolog 0.0053 0.0475 0.0865
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0112 0.0967
Entamoeba histolytica cysteine protease, putative 0.0031 0.0153 0.157
Brugia malayi Serotonin receptor 0.0317 0.4412 0.5684
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.005 0.0437 0.0437
Echinococcus multilocularis cathepsin b 0.0283 0.3904 0.3904
Onchocerca volvulus 0.0317 0.4412 1
Brugia malayi Dopamine receptor 0.0317 0.4412 0.5684
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.0272 0.0272
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0186 0.2461 0.2461
Echinococcus multilocularis cathepsin L cysteine protease 0.0053 0.0475 0.0475
Onchocerca volvulus 0.0317 0.4412 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Echinococcus granulosus importin subunit beta 1 0.0029 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Mycobacterium ulcerans glutaminase 0.0271 0.3718 0.9556
Plasmodium falciparum glutathione reductase 0.0066 0.0672 1
Loa Loa (eye worm) hypothetical protein 0.0186 0.2461 0.2461
Echinococcus granulosus cyclin dependent kinase 5 0.005 0.0437 0.0437
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0475 0.1279
Brugia malayi putative neuropeptide receptor 0.0317 0.4412 0.5684
Echinococcus granulosus neuropeptide s receptor 0.0317 0.4412 0.4412
Echinococcus multilocularis cyclin dependent kinase 9 0.0062 0.061 0.061
Echinococcus granulosus alpha 1A adrenergic receptor 0.0317 0.4412 0.4412
Onchocerca volvulus 0.0317 0.4412 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0053 0.0475 0.1279
Echinococcus granulosus neuropeptides capa receptor 0.0317 0.4412 0.4412
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0032 0.0158 0.0158
Schistosoma mansoni sodium-dependent amino acid transporter 0.0032 0.0158 0.0158
Brugia malayi G protein-coupled receptor F59B2.13 0.0317 0.4412 0.5684
Echinococcus granulosus cyclin dependent kinase 9 0.0062 0.061 0.061
Leishmania major cathepsin L-like protease 0.0053 0.0475 0.4095
Brugia malayi Bromodomain containing protein 0.0032 0.0171 0.022
Trypanosoma brucei cdc2-related kinase 1 0.005 0.0437 0.3764
Echinococcus multilocularis dro:myosuppressin receptor 0.0317 0.4412 0.4412
Trypanosoma cruzi trypanothione reductase, putative 0.0066 0.0672 0.1721
Echinococcus granulosus g protein coupled receptor 0.0317 0.4412 0.4412
Brugia malayi hypothetical protein 0.0317 0.4412 0.5684
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0023 0.0028 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0223 0.06
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0242 0.0651
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0067 0.0684 0.1698
Echinococcus multilocularis microtubule associated protein 2 0.0675 0.9739 0.9739
Echinococcus multilocularis serotonin transporter 0.0186 0.2461 0.2461
Entamoeba histolytica cyclin family protein 0.0036 0.0223 0.2293
Schistosoma mansoni cyclin B 0.0086 0.0973 0.0973
Brugia malayi Cyclin, N-terminal domain containing protein 0.0036 0.0223 0.0287
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.4412 0.4412
Onchocerca volvulus 0.0053 0.0475 0.0865
Loa Loa (eye worm) G-protein coupled receptor 0.0317 0.4412 0.4412
Echinococcus granulosus rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Echinococcus granulosus cyclins 0.0036 0.0223 0.0223
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0475 0.1279
Onchocerca volvulus 0.0038 0.0255 0.0354
Entamoeba histolytica cysteine proteinase, putative 0.0031 0.0153 0.157
Echinococcus multilocularis cyclins 0.0036 0.0223 0.0223
Onchocerca volvulus 0.0053 0.0475 0.0865
Loa Loa (eye worm) hypothetical protein 0.0037 0.0242 0.0242
Trichomonas vaginalis cyclin A, putative 0.0086 0.0973 0.2617
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0317 0.4412 0.4412
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0023 0.0028 0.0422
Schistosoma mansoni microtubule-associated protein tau 0.0675 0.9739 0.9739
Echinococcus granulosus allatostatin A receptor 0.0317 0.4412 0.4412
Trichomonas vaginalis cyclin D, putative 0.0036 0.0223 0.06
Echinococcus multilocularis cyclin B3 1 0.0036 0.0223 0.0223
Brugia malayi Cyclin, N-terminal domain containing protein 0.0086 0.0973 0.1253
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0106 0.1271 0.1271
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.4412 0.4412
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0023 0.0028 0.0073
Brugia malayi neuropeptide F receptor 0.0317 0.4412 0.5684
Schistosoma mansoni glutamate receptor NMDA 0.0056 0.0519 0.0519
Echinococcus multilocularis sex peptide receptor 0.0317 0.4412 0.4412
Trichomonas vaginalis glutathione reductase, putative 0.0023 0.0028 0.0076
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0032 0.0158 0.0158
Echinococcus multilocularis cyclins 0.0036 0.0223 0.0223
Echinococcus granulosus cyclin B 0.0086 0.0973 0.0973
Echinococcus multilocularis neuropeptide receptor 0.0317 0.4412 0.4412
Plasmodium falciparum cysteine proteinase falcipain 1 0.0031 0.0153 0.2273
Echinococcus granulosus tm gpcr rhodopsin 0.0317 0.4412 0.4412
Onchocerca volvulus 0.0317 0.4412 1
Onchocerca volvulus 0.0317 0.4412 1
Echinococcus granulosus serotonin receptor 0.0317 0.4412 0.4412
Trichomonas vaginalis cyclins, putative 0.0086 0.0973 0.2617
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0242 0.0242
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0153 0.0411
Echinococcus granulosus cyclin b3 0.0036 0.0223 0.0223
Echinococcus granulosus cathepsin L 0.0031 0.0153 0.0153
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0475 0.4095
Echinococcus multilocularis glutamate receptor 4 0.0042 0.0309 0.0309
Echinococcus granulosus microtubule associated protein 2 0.0675 0.9739 0.9739
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0317 0.4412 0.4412
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0242 0.0553
Giardia lamblia Cathepsin B precursor 0.0099 0.1161 1
Leishmania major cyclin 0.0086 0.0973 0.8381
Schistosoma mansoni neuropeptide f receptor 76f 0.0317 0.4412 0.4412
Echinococcus granulosus tm gpcr rhodopsin 0.0317 0.4412 0.4412
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0032 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) G-protein coupled receptor 0.0317 0.4412 0.4412
Onchocerca volvulus 0.0037 0.0242 0.0323
Brugia malayi cathepsin B-like cysteine proteinase 0.0283 0.3904 0.5029
Echinococcus granulosus cathepsin b 0.0283 0.3904 0.3904
Onchocerca volvulus 0.0032 0.0158 0.0128
Plasmodium falciparum thioredoxin reductase 0.0066 0.0672 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0475 0.4095
Echinococcus granulosus rhodopsin orphan GPCR 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0158
Echinococcus granulosus fmrfamide receptor 0.0317 0.4412 0.4412
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0317 0.4412 0.4412
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0032 0.0158 0.0158
Brugia malayi Papain family cysteine protease containing protein 0.0053 0.0475 0.0612
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Brugia malayi hypothetical protein 0.0317 0.4412 0.5684
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0437 0.1175
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) ctsf protein 0.0053 0.0475 0.0475
Loa Loa (eye worm) hypothetical protein 0.0037 0.0242 0.0242
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0023 0.0028 0.0422
Onchocerca volvulus 0.0053 0.0475 0.0865
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Entamoeba histolytica cysteine proteinase, putative 0.0053 0.0475 0.4887
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0023 0.0028 0.0244
Entamoeba histolytica hypothetical protein 0.0023 0.0032 0.0327
Brugia malayi beta-lactamase family protein 0.0037 0.0242 0.0312
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0067 0.0684 0.1698
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0283 0.3904 1
Schistosoma mansoni amine GPCR 0.0317 0.4412 0.4412
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0272 0.0272
Entamoeba histolytica cysteine proteinase, putative 0.0038 0.0255 0.2625
Plasmodium vivax importin-beta 2, putative 0.0029 0.0112 0.1671
Mycobacterium ulcerans short chain dehydrogenase 0.0282 0.389 1
Echinococcus granulosus glutamate receptor 2 0.0072 0.0752 0.0752
Trypanosoma cruzi cdc2-related kinase 3 0.005 0.0437 0.1119
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0317 0.4412 0.4412
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0106 0.1271 0.1271
Echinococcus multilocularis snurportin 1 0.0305 0.4226 0.4226
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0317 0.4412 0.4412
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0317 0.4412 0.5684
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0028 0.0073
Brugia malayi hypothetical protein 0.0032 0.0158 0.0203
Brugia malayi larval opioid receptor 0.0317 0.4412 0.5684
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Entamoeba histolytica cysteine protease, putative 0.0031 0.0153 0.157
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0317 0.4412 0.4412
Loa Loa (eye worm) TYRA-2 protein 0.0317 0.4412 0.4412
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0171 0.147
Schistosoma mansoni neuropeptide F-like receptor 0.0317 0.4412 0.4412
Giardia lamblia Cyclin A 0.0036 0.0223 0.1922
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0037 0.0242 0.0242
Brugia malayi Dopamine receptor protein 1 0.0317 0.4412 0.5684
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0032 0.0158 0.136
Schistosoma mansoni sodium/chloride dependent transporter 0.0033 0.0171 0.0171
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0242 0.0553
Plasmodium falciparum glutathione reductase 0.0023 0.0028 0.0422
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0032 0.0158 0.0203
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0032 0.0158 0.0158
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.005 0.0437 0.3764
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0317 0.4412 0.4412
Brugia malayi cyclin-dependent kinase 9 0.0053 0.0475 0.0611
Trypanosoma cruzi CYC2-like cyclin, putative 0.0086 0.0973 0.2492
Plasmodium falciparum thioredoxin reductase 0.0023 0.0028 0.0422
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0023 0.0028 0.0244
Loa Loa (eye worm) hypothetical protein 0.0317 0.4412 0.4412
Echinococcus granulosus g protein coupled receptor 0.0317 0.4412 0.4412
Mycobacterium tuberculosis Conserved protein 0.0037 0.0242 0.0553
Echinococcus multilocularis serotonin receptor 0.0692 1 1
Plasmodium vivax protein kinase Crk2 0.005 0.0437 0.6503
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0242 0.0553
Schistosoma mansoni sodium/chloride dependent transporter 0.0186 0.2461 0.2461
Loa Loa (eye worm) hypothetical protein 0.0086 0.0973 0.0973
Echinococcus multilocularis serotonin receptor 0.0692 1 1
Brugia malayi Cathepsin L-like precursor 0.0038 0.0255 0.0329
Echinococcus granulosus cyclins 0.0036 0.0223 0.0223
Echinococcus multilocularis neuropeptides capa receptor 0.0317 0.4412 0.4412
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0475 0.1279
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0158
Onchocerca volvulus 0.0317 0.4412 1
Plasmodium falciparum transporter, putative 0.0032 0.0158 0.235
Schistosoma mansoni sodium/chloride dependent transporter 0.0032 0.0158 0.0158
Entamoeba histolytica cysteine proteinase, putative 0.0053 0.0475 0.4887
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0475 0.4095
Echinococcus granulosus g-protein coupled receptor 0.0317 0.4412 0.4412
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0317 0.4412 0.4412
Loa Loa (eye worm) hypothetical protein 0.0086 0.0973 0.0973
Entamoeba histolytica cysteine protease, putative 0.0031 0.0153 0.157
Echinococcus granulosus orexin receptor type 2 0.0317 0.4412 0.4412
Schistosoma mansoni hypothetical protein 0.0305 0.4226 0.4226

Activities

Activity type Activity value Assay description Source Reference
Log Ki (binding) = 5.2 Binding affinity determined to alpha-1 adrenergic receptor of rat cerebral cortex using [3H]-prazosin as radioligand ChEMBL. 2153820
Log Ki (binding) = 6.74 Binding affinity to alpha-2 adrenergic receptor of rat cerebral cortex assayed using [3H]-yohimbine as radioligand ChEMBL. 2153820
Log Ki (binding) = 7.62 Binding affinity to the alpha-2 adrenergic receptor of rat cerebral cortex assayed using [3H]-idazoxan as radioligand ChEMBL. 2153820
Ratio (binding) = 8 Antilog of [3H]-idazoxan pKi minus [3H]-yohimbine pKi ChEMBL. 2153820
Selectivity ratio (binding) = 35 Selectivity ratio for alpha 2 adrenergic receptor subpopulation, [3H]-yohimbine pKi minus [3H]-prazosin pKi ChEMBL. 2153820

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.