Detailed information for compound 302077

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 295.291 | Formula: C13H17N3O5
  • H donors: 5 H acceptors: 5 LogP: -3.54 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C[C@@H](C(=O)N[C@H](C(=O)N)Cc1ccc(cc1)O)N
  • InChi: 1S/C13H17N3O5/c14-9(6-11(18)19)13(21)16-10(12(15)20)5-7-1-3-8(17)4-2-7/h1-4,9-10,17H,5-6,14H2,(H2,15,20)(H,16,21)(H,18,19)/t9-,10-/m0/s1
  • InChiKey: QBCNRXDCPKUBJZ-UWVGGRQHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis hepatoma derived growth factor protein 0.001 0.0005 0.0005
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0272 0.0272
Echinococcus granulosus dna polymerase eta 0.0067 0.137 0.137
Onchocerca volvulus 0.0012 0.0052 0.0082
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0418 0.0565
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0215 0.0248
Echinococcus granulosus flap endonuclease 1 0.0027 0.0418 0.0418
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.151 0.228
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0001
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0235 0.0426
Schistosoma mansoni phosphoglycerate kinase 0.0177 0.4025 0.4025
Entamoeba histolytica hypothetical protein 0.0037 0.0667 0.1647
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0065 0.133 0.1811
Entamoeba histolytica hypothetical protein 0.0012 0.0052 0.0117
Schistosoma mansoni bromodomain containing protein 0.0067 0.1391 0.1391
Plasmodium falciparum flap endonuclease 1 0.0027 0.0418 0.0922
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0911 0.0911
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0283 0.0421
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0272 0.0272
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0911 0.1373
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0583 0.1438
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0818 0.1419
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0011 0.0034 0.0044
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0012 0.0052 0.00000000048606
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0066 0.0084
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0272 0.0272
Loa Loa (eye worm) RecQ helicase 0.0047 0.0901 0.1358
Schistosoma mansoni hypothetical protein 0.001 0.0005 0.0005
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0032 0.0534 0.1213
Onchocerca volvulus 0.001 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0001
Schistosoma mansoni glutaminase 0.0284 0.6606 0.6606
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0235 0.0349
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0829 0.1127
Trypanosoma brucei polo-like protein kinase 0.0098 0.213 0.2904
Brugia malayi PHD-finger family protein 0.0028 0.0431 0.0646
Onchocerca volvulus 0.001 0.0005 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0911 0.0911
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0058 0.0072
Loa Loa (eye worm) glutaminase 2 0.0284 0.6606 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0034 0.0044
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0049 0.095 0.2352
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.0983 0.0983
Entamoeba histolytica hypothetical protein 0.0012 0.0058 0.0132
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0177 0.4025 0.6062
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0272 0.0272
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0373 0.0503
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0557 0.0557
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0272 0.0467
Leishmania major phosphoglycerate kinase B, cytosolic 0.0177 0.4025 0.5493
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0235 0.0235
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.213 0.3171
Loa Loa (eye worm) hypothetical protein 0.0073 0.1536 0.232
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0052 0.00000000048606
Echinococcus granulosus hepatoma derived growth factor protein 0.001 0.0005 0.0005
Echinococcus multilocularis muscleblind protein 0.0155 0.3504 0.3504
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0373 0.0915
Echinococcus granulosus PWWP domain containing protein 2A 0.001 0.0005 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0272 0.0405
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0732 0.0994
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0911 0.1373
Entamoeba histolytica serine/threonine protein kinase, putative 0.0098 0.213 0.5287
Leishmania major hypothetical protein, conserved 0.0016 0.0149 0.0198
Trypanosoma brucei unspecified product 0.0028 0.0433 0.0585
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0012 0.0066 0.0153
Brugia malayi Muscleblind-like protein 0.0155 0.3504 0.5301
Brugia malayi Bromodomain containing protein 0.008 0.1684 0.2544
Brugia malayi bZIP transcription factor family protein 0.0163 0.3695 0.5591
Loa Loa (eye worm) hypothetical protein 0.0021 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0072
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0005 0.0005
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0666 0.0666
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0314 0.7323 1
Schistosoma mansoni nuclear hormone receptor 0.001 0.0005 0.0005
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0237 0.0318
Schistosoma mansoni DNA helicase recq1 0.0019 0.0235 0.0235
Loa Loa (eye worm) helicase 0.0012 0.0052 0.0072
Schistosoma mansoni DNA helicase recq5 0.0019 0.0235 0.0235
Schistosoma mansoni hypothetical protein 0.001 0.0005 0.0005
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0272 0.0272
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0583 0.1438
Echinococcus granulosus peregrin 0.0012 0.0064 0.0064
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0005 0.0005
Plasmodium vivax DNA repair protein REV1, putative 0.0012 0.0066 0.0036
Loa Loa (eye worm) hypothetical protein 0.0159 0.3587 0.5428
Loa Loa (eye worm) hypothetical protein 0.0021 0.0272 0.0405
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0237 0.0352
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0235 0.0235
Trypanosoma brucei chrX additional, unordered contigs 0.0012 0.0066 0.0084
Echinococcus multilocularis expressed protein 0.0035 0.0602 0.0602
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0732 0.0994
Echinococcus multilocularis chromobox protein 1 0.0072 0.151 0.151
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0911 0.0911
Schistosoma mansoni hypothetical protein 0.0037 0.0667 0.0667
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0148 0.3343 0.4561
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0583 0.079
Toxoplasma gondii exonuclease III APE 0.002 0.0237 0.0578
Echinococcus multilocularis muscleblind protein 1 0.0155 0.3504 0.3504
Echinococcus granulosus Chromobox protein 3 0.0012 0.0052 0.0052
Brugia malayi Pre-SET motif family protein 0.0218 0.5017 0.7593
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0314 0.7323 1
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0235 0.0349
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0602 0.0905
Schistosoma mansoni hypothetical protein 0.0012 0.0052 0.0052
Trypanosoma brucei unspecified product 0.004 0.0732 0.0994
Brugia malayi Nuclear hormone receptor E75 0.001 0.0005 0.0001
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0098 0.213 0.213
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0237 0.0318
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.1346 0.1346
Brugia malayi M-phase phosphoprotein, mpp8 0.0012 0.0052 0.0072
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0177 0.4025 1
Echinococcus multilocularis zinc finger protein 0.0022 0.0297 0.0297
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0066 0.0084
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.1061 0.1444
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0418 0.0559
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0272 0.0272
Schistosoma mansoni kinase 0.005 0.0968 0.0968
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0034 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0034 0.0044
Schistosoma mansoni SET domain protein 0.0036 0.063 0.063
Trypanosoma brucei phosphoglycerate kinase 0.0177 0.4025 0.5493
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0418 0.0626
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0732 0.0732
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0272 0.0272
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0272 0.0405
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0314 0.7323 1
Echinococcus multilocularis PWWP domain containing protein 2A 0.001 0.0005 0.0005
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0525 0.1293
Schistosoma mansoni coup transcription factor 0.0021 0.0272 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0732 0.0994
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0052 0.0117
Schistosoma mansoni DNA polymerase eta 0.0067 0.137 0.137
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0732 0.1102
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.213 0.3171
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0272 0.0405
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0193 0.0193
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0052 0.0117
Echinococcus multilocularis chromobox protein 2 0.0012 0.0052 0.0052
Echinococcus granulosus Chromo domain 0.0012 0.0052 0.0052
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0237 0.0261
Trichomonas vaginalis chromobox protein, putative 0.0072 0.151 0.2224
Loa Loa (eye worm) hypothetical protein 0.0012 0.0066 0.0093
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0036 0.063 0.063
Leishmania major DNA polymerase kappa, putative 0.0012 0.0066 0.0084
Schistosoma mansoni hepatoma derived growth factor 0.001 0.0005 0.0005
Schistosoma mansoni ap endonuclease 0.002 0.0237 0.0237
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.0662 0.0662
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0052 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0732 0.0994
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0583 0.079
Schistosoma mansoni hypothetical protein 0.0016 0.0149 0.0149
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0557 0.1373
Schistosoma mansoni flap endonuclease-1 0.0024 0.0356 0.0356
Brugia malayi Protein cec-1. 0.0012 0.0052 0.0072
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0012 0.0066 0.0153
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0072
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0732 0.0994
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0732 0.0994
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0272 0.0405
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0732 0.0732
Leishmania major mitochondrial DNA polymerase beta 0.0314 0.7323 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0732 0.0994
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0418 0.0418
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0732 0.1018
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0215 0.0248
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0732 0.1307
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0272 0.0272
Brugia malayi hypothetical protein 0.0072 0.1506 0.2275
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0193 0.0193
Brugia malayi glutaminase DH11.1 0.0284 0.6606 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.213 0.2904
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0732 0.1102
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0044 0.0044
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0052 0.0072
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0829 0.1127
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0237 0.0432
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0023 0.0323 0.0435
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0001
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0272 0.0272
Brugia malayi tailless protein 0.001 0.0005 0.0001
Onchocerca volvulus Serine\/threonine kinase homolog 0.0098 0.213 0.3708
Echinococcus multilocularis peregrin 0.0012 0.0064 0.0064
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0829 0.1127
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0732 0.0994
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0037 0.0667 0.1647
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0486 0.0486
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0021 0.0022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0139 0.0133
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0072 0.1506 0.1506
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0177 0.4025 1
Brugia malayi Heterochromatin protein 1 0.0072 0.151 0.228
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0058 0.0009
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0218 0.5017 0.7593
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0732 0.0994
Brugia malayi nuclear hormone receptor 0.001 0.0005 0.0001
Echinococcus granulosus muscleblind protein 0.0155 0.3504 0.3504
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0732 0.0994
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.001 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0744 0.1056
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0072
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.0021 0.0272 0.0405
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0732 0.1018
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0177 0.4025 1
Leishmania major DNA polymerase eta, putative 0.0067 0.137 0.1865
Echinococcus multilocularis PWWP domain containing protein 2A 0.001 0.0005 0.0005
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0034 0.0044
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0052 0.0052
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0163 0.3695 0.3695
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0001
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0052 0.0052
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0372 0.0372
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0215 0.0248
Trypanosoma cruzi ISWI complex protein 0.0016 0.0149 0.0198
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0911 0.0911
Onchocerca volvulus 0.0128 0.2851 0.4967
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0034 0.0044
Schistosoma mansoni chromobox protein 0.0012 0.0052 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0058 0.0072
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0583 0.079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0235 0.0349
Loa Loa (eye worm) glutaminase 0.0284 0.6606 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0272 0.0405
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0732 0.0994
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.0983 0.0983
Brugia malayi nuclear receptor RXR 0.0011 0.0034 0.0044
Brugia malayi Nuclear hormone receptor E75 0.001 0.0005 0.0001
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0141 0.0141
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0485 0.0728
Echinococcus granulosus expressed protein 0.0035 0.0602 0.0602
Brugia malayi chromobox protein homolog 3 0.0041 0.0744 0.112
Echinococcus multilocularis phosphoglycerate kinase 1 0.0177 0.4025 0.4025
Trypanosoma cruzi ISWI complex protein 0.0016 0.0149 0.0198
Schistosoma mansoni chromobox protein 0.0072 0.151 0.151
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0177 0.4025 0.5
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.0763 0.1791
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0039 0.0704 0.1739
Loa Loa (eye worm) hypothetical protein 0.004 0.0727 0.1094
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0052 0.00000000029463
Loa Loa (eye worm) hypothetical protein 0.0011 0.0034 0.0044
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0013 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0155 0.3504 0.5301
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0005 0.0005
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0418 0.0565
Loa Loa (eye worm) hypothetical protein 0.0042 0.0786 0.1183
Schistosoma mansoni phd finger protein 0.0012 0.0064 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.0021 0.0272 0.0405
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0372 0.0372
Trypanosoma brucei unspecified product 0.0028 0.0433 0.0585
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0237 0.0283
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0139 0.0133
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0005 0.0005
Echinococcus granulosus chromobox protein 2 0.0012 0.0052 0.0052
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0272 0.0272
Brugia malayi Flap endonuclease-1 0.0027 0.0418 0.0626
Brugia malayi hypothetical protein 0.0037 0.0667 0.1003
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0177 0.4025 0.5493
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0072
Schistosoma mansoni cpg binding protein 0.0034 0.0574 0.0574
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0911 0.0911
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0911 0.0911
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0005 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0433 0.0585
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.213 0.2904
Echinococcus multilocularis chromobox protein 1 0.0072 0.151 0.151
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0732 0.181
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0272 0.0272
Echinococcus multilocularis jun protein 0.0163 0.3695 0.3695
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0418 0.0922
Schistosoma mansoni chromobox protein 0.0012 0.0052 0.0052
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0058 0.0072
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0001
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0272 0.0272
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0272 0.0467
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0215 0.0248
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0235 0.0573
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0667 0.0667
Brugia malayi hypothetical protein 0.001 0.0005 0.0001
Brugia malayi SET domain containing protein 0.0015 0.0122 0.0179
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.213 0.3171
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0215 0.0248
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0034 0.0034
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0237 0.0283
Loa Loa (eye worm) hypothetical protein 0.0041 0.0744 0.112
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0021 0.0022
Trichomonas vaginalis rotamase, putative 0.0035 0.0602 0.084
Onchocerca volvulus 0.003 0.0485 0.0838
Echinococcus multilocularis bloom syndrome protein 0.0047 0.0901 0.0901
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0215 0.0248
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0272 0.0405
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0052 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0066 0.0084
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0272 0.0405
Schistosoma mansoni chromobox protein 0.0072 0.151 0.151
Brugia malayi serine/threonine-protein kinase plk-2 0.0098 0.213 0.3219
Echinococcus granulosus dna polymerase kappa 0.004 0.0732 0.0732
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0272 0.0272
Trypanosoma brucei phosphoglycerate kinase 0.0065 0.133 0.1811
Loa Loa (eye worm) hypothetical protein 0.0072 0.1506 0.2275
Schistosoma mansoni jun-related protein 0.0133 0.2959 0.2959
Giardia lamblia DINP protein human, muc B family 0.004 0.0732 0.1682
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0005 0.0001
Brugia malayi hypothetical protein 0.0011 0.0034 0.0044
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0058 0.0072
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0272 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0732 0.0994
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.1301 0.1301
Loa Loa (eye worm) hypothetical protein 0.0177 0.4025 0.609
Schistosoma mansoni hepatoma derived growth factor 0.001 0.0005 0.0005
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0373 0.0503
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0732 0.1038
Entamoeba histolytica hypothetical protein 0.0012 0.0058 0.0132
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0372 0.0372
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0583 0.079
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0215 0.0248
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0023 0.0323 0.0435
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0072
Brugia malayi polk-prov protein 0.0012 0.0066 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0272 0.0405
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0418 0.1028
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0193 0.0193
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.213 0.3171
Trichomonas vaginalis rotamase, putative 0.0034 0.0583 0.081
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0001
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0148 0.3343 0.4561
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0936 0.135
Onchocerca volvulus 0.0021 0.0272 0.0467
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0235 0.0349
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0272 0.0405
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0272 0.0272
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.0021 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0001
Plasmodium vivax SET domain protein, putative 0.0033 0.0557 0.127
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0272 0.0272
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0602 0.084
Entamoeba histolytica phosphoglycerate kinase, putative 0.0177 0.4025 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0005 0.0005
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0272 0.0272
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0034 0.0034
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0272 0.0467
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0098 0.213 0.213
Brugia malayi ImpB/MucB/SamB family protein 0.0067 0.137 0.2068
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0001
Leishmania major DNA damage repair protein, putative 0.0012 0.0066 0.0084
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0127 0.0115
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0818 0.1169
Loa Loa (eye worm) hypothetical protein 0.0051 0.0983 0.1482
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0272 0.0405
Echinococcus multilocularis Chromo domain 0.0012 0.0052 0.0052
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0237 0.0352
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0013 0.0075 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0433 0.0585
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0072
Entamoeba histolytica hypothetical protein 0.0012 0.0052 0.0117
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0001
Schistosoma mansoni zinc finger protein 0.001 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0272 0.0405
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.213 0.3171
Loa Loa (eye worm) hypothetical protein 0.0067 0.137 0.2068
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0209 0.0309
Echinococcus multilocularis cpg binding protein 0.0034 0.0574 0.0574
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0272 0.0405
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0052 0.0052
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0272 0.0272
Echinococcus granulosus histone lysine methyltransferase setb 0.0051 0.0983 0.0983
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0005 0.0001
Brugia malayi nuclear receptor NHR-88 0.0021 0.0272 0.0405
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.1301 0.1301
Schistosoma mansoni phosphoglycerate kinase 0.0177 0.4025 0.4025
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0911 0.0911
Echinococcus granulosus phosphoglycerate kinase 1 0.0177 0.4025 0.4025
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0021 0.0022
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0141 0.0206
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0058 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0272 0.0405
Entamoeba histolytica recQ family DNA helicase 0.001 0.0005 0.0002
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0066 0.0084
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0005 0.0005
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0272 0.0405
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0418 0.0565
Schistosoma mansoni rotamase 0.0035 0.0602 0.0602
Schistosoma mansoni DNA polymerase IV / kappa 0.0012 0.0066 0.0066
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0148 0.3343 0.4561
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0235 0.0461
Schistosoma mansoni ap endonuclease 0.002 0.0237 0.0237
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0005 0.0001
Schistosoma mansoni cpg binding protein 0.003 0.0485 0.0485
Giardia lamblia Phosphoglycerate kinase 0.0177 0.4025 1
Loa Loa (eye worm) hypothetical protein 0.0143 0.3216 0.4864
Brugia malayi steroid hormone receptor 0.0021 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0001
Schistosoma mansoni nuclear receptor 0.001 0.0005 0.0005
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0044 0.0044
Echinococcus granulosus cpg binding protein 0.0034 0.0574 0.0574
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0272 0.0272
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.213 0.213
Schistosoma mansoni cpg binding protein 0.0034 0.0574 0.0574
Echinococcus granulosus jun protein 0.0163 0.3695 0.3695
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0058 0.0072
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0005 0.0001
Onchocerca volvulus 0.0032 0.0533 0.0921
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0458 0.062
Brugia malayi nuclear hormone receptor 0.0021 0.0272 0.0405
Schistosoma mansoni zinc finger protein 0.0016 0.0149 0.0149
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0058 0.0072
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0177 0.4025 0.5493
Trichomonas vaginalis DNA helicase recq1, putative 0.0047 0.0901 0.1296
Loa Loa (eye worm) hypothetical protein 0.0021 0.0272 0.0405
Echinococcus granulosus chromobox protein 1 0.0072 0.151 0.151
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0072 0.1506 0.1506
Brugia malayi hypothetical protein 0.0011 0.0034 0.0044
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0418 0.1028
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0272 0.0405
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0058 0.0072
Schistosoma mansoni nuclear receptor 0.001 0.0005 0.0005
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0005 0.0005
Onchocerca volvulus 0.0045 0.0842 0.1461
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0065 0.133 0.1811
Echinococcus multilocularis dna polymerase kappa 0.004 0.0732 0.0732
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0433 0.0585
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0418 0.0889
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0141 0.0141
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0272 0.0272
Entamoeba histolytica hypothetical protein 0.0012 0.0052 0.0117
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0235 0.0235
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0666 0.0666
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0052 0.0072
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0058 0.0072
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0732 0.0994
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0005 0.0001
Plasmodium falciparum DNA repair protein REV1, putative 0.0012 0.0066 0.0036
Brugia malayi hypothetical protein 0.0012 0.0052 0.0072
Plasmodium falciparum phosphoglycerate kinase 0.0177 0.4025 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0235 0.0573
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0066 0.0084
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0602 0.0905
Trichomonas vaginalis chromobox protein, putative 0.0072 0.151 0.2224
Brugia malayi nuclear receptor RXR 0.001 0.0005 0.0001
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0005 0.0001
Leishmania major phosphoglycerate kinase C, glycosomal 0.0177 0.4025 0.5493
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0704 0.0955
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0936 0.135
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0034 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0842 0.0842
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0732 0.0994
Brugia malayi Bloom's syndrome protein homolog 0.0047 0.0901 0.1358
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0098 0.213 0.2904
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.213 0.3171
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0141 0.0141
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0215 0.0248
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0744 0.1056
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0237 0.0466
Chlamydia trachomatis phosphoglycerate kinase 0.0177 0.4025 0.5
Mycobacterium ulcerans phosphoglycerate kinase 0.0177 0.4025 0.6053
Entamoeba histolytica hypothetical protein 0.0037 0.0667 0.1647
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0829 0.1127
Loa Loa (eye worm) hypothetical protein 0.0155 0.3504 0.5301
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.213 0.3171
Brugia malayi ecdysone receptor 0.001 0.0005 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0052 0.00000000029463
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0058 0.0009
Trichomonas vaginalis set domain proteins, putative 0.0248 0.5736 0.8673
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0052 0.0072
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0066 0.0084
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0901 0.1296
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0272 0.0405
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0272 0.0272
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0036 0.063 0.063
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0732 0.0994
Echinococcus granulosus PWWP domain containing protein 2A 0.001 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0732 0.0994
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0177 0.4025 0.6062
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0058 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0272 0.0405
Mycobacterium ulcerans glutaminase 0.0284 0.6606 1
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0005 0.0005
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0237 0.0318
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0818 0.1169
Mycobacterium tuberculosis Conserved hypothetical protein 0.0165 0.3747 0.9266
Entamoeba histolytica hypothetical protein 0.0012 0.0058 0.0132
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0065 0.133 0.1811
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0373 0.0489
Loa Loa (eye worm) hypothetical protein 0.0046 0.0875 0.1318
Brugia malayi CXXC zinc finger family protein 0.003 0.0485 0.0728
Schistosoma mansoni tsg101-related 0.0049 0.095 0.095
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0237 0.0466
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0012 0.0052 0.0117
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0065 0.133 0.1811
Brugia malayi conserved hypotetical protein 0.001 0.0005 0.0001
Brugia malayi hypothetical protein 0.0128 0.2851 0.4313
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0237 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0458 0.062
Brugia malayi ecdysteroid receptor 0.0021 0.0272 0.0405
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0732 0.0732
Echinococcus granulosus bloom syndrome protein 0.0047 0.0901 0.0901
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0237 0.0541
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0557 0.0557
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0005 0.0005
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0235 0.0235
Trypanosoma brucei phosphoglycerate kinase 0.0177 0.4025 0.5493
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0272 0.0272
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0005 0.0002
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0051 0.0983 0.0983
Brugia malayi Phosphoglycerate kinase 0.0177 0.4025 0.609
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0732 0.0994
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0052 0.0052
Entamoeba histolytica hypothetical protein 0.0037 0.0667 0.1647
Echinococcus multilocularis dna polymerase eta 0.0067 0.137 0.137
Brugia malayi Bromodomain containing protein 0.004 0.0725 0.1091
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0272 0.0272
Schistosoma mansoni SET domain protein 0.0016 0.0164 0.0164
Brugia malayi Pre-SET motif family protein 0.0033 0.0557 0.0836
Leishmania major DNA polymerase eta, putative 0.0039 0.0704 0.0955
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0001
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0667 0.0667
Trypanosoma brucei ISWI complex protein 0.0016 0.0149 0.0198
Loa Loa (eye worm) hypothetical protein 0.0021 0.0272 0.0405
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0052 0.0117
Schistosoma mansoni nuclear hormone receptor 0.001 0.0005 0.0005
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0732 0.0732
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0237 0.0318
Leishmania major hypothetical protein, conserved 0.0023 0.0323 0.0435
Schistosoma mansoni hypothetical protein 0.0133 0.2959 0.2959
Schistosoma mansoni hypothetical protein 0.0425 1 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.1242 0.3078
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0066 0.0084
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0005 0.0001
Trichomonas vaginalis glutaminase, putative 0.0284 0.6606 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0732 0.1038
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0066 0.0084
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0052 0.00000000029463
Loa Loa (eye worm) hypothetical protein 0.0011 0.0034 0.0044
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0011 0.0021 0.004
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0272 0.0405
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0667 0.0667
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0272 0.0272
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0058 0.0072
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0237 0.0578
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0272 0.0405
Trypanosoma brucei DNA polymerase eta, putative 0.0067 0.137 0.1865
Giardia lamblia Kinase, PLK 0.0098 0.213 0.5213
Entamoeba histolytica hypothetical protein 0.0012 0.0058 0.0132
Brugia malayi CHD4 protein 0.0016 0.0141 0.0206
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0066 0.0084
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0373 0.0503
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0044 0.0059
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0072
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0272 0.0272
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0163 0.3695 0.3695
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0065 0.133 0.1811
Schistosoma mansoni zinc finger protein 0.0022 0.0297 0.0297
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0732 0.0994
Echinococcus multilocularis dnaJ subfamily B 0.0425 1 1
Brugia malayi Phosphoglycerate kinase 0.0065 0.133 0.2007
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0732 0.1307
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0066 0.0084
Trypanosoma cruzi DNA polymerase eta, putative 0.0067 0.137 0.1865
Echinococcus granulosus chromobox protein 1 0.0072 0.151 0.151
Loa Loa (eye worm) hypothetical protein 0.0032 0.0533 0.08
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0089 0.0127
Schistosoma mansoni tsg101-related 0.006 0.1215 0.1215
Schistosoma mansoni tsg101-related 0.006 0.1215 0.1215
Echinococcus granulosus zinc finger protein 0.0022 0.0297 0.0297
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0272 0.0405
Trypanosoma brucei phosphoglycerate kinase, putative 0.0065 0.133 0.1811
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0058 0.0072
Leishmania major DNA polymerase kappa, putative 0.004 0.0732 0.0994
Loa Loa (eye worm) DR-78 0.001 0.0005 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0272 0.0405
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0005 0.0001
Schistosoma mansoni hypothetical protein 0.0021 0.0283 0.0283
Toxoplasma gondii hypothetical protein 0.0051 0.0985 0.2439
Treponema pallidum phosphoglycerate kinase 0.0177 0.4025 1
Brugia malayi nuclear receptor NHR-67 0.001 0.0005 0.0001
Mycobacterium ulcerans hypothetical protein 0.0165 0.3747 0.5628
Plasmodium vivax phosphoglycerate kinase, putative 0.0177 0.4025 1
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0098 0.213 0.3219
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0744 0.1289
Brugia malayi hypothetical protein 0.001 0.0005 0.0001
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0058 0.0072
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0052 0.0117
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0005 0.0005
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0272 0.0272
Onchocerca volvulus 0.0248 0.5736 1
Trichomonas vaginalis hypothetical protein 0.0035 0.0614 0.0858
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0011 0.0021 0.0022
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0058 0.0072
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0237 0.0577
Onchocerca volvulus 0.0012 0.0052 0.0082
Brugia malayi nuclear receptor NHR-88 0.001 0.0005 0.0001
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0177 0.4025 1
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0065 0.133 0.1811
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0052 0.0117

Activities

Activity type Activity value Assay description Source Reference
Taste class (functional) = 0 Quality of taste by acting at receptor site; Bitter ChEMBL. 3712380

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.