Detailed information for compound 410533

Basic information

Technical information
  • TDR Targets ID: 410533
  • Name: 5-pyridin-2-ylthiophene-2-sulfonohydrazide
  • MW: 255.317 | Formula: C9H9N3O2S2
  • H donors: 2 H acceptors: 3 LogP: 0.78 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: NNS(=O)(=O)c1ccc(s1)c1ccccn1
  • InChi: 1S/C9H9N3O2S2/c10-12-16(13,14)9-5-4-8(15-9)7-3-1-2-6-11-7/h1-6,12H,10H2
  • InChiKey: MBEZESPCDNRIKO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-(2-pyridyl)thiophene-2-sulfonohydrazide
  • 5-(2-pyridyl)-2-thiophenesulfonohydrazide
  • Maybridge1_004801
  • SR-01000635294-1
  • ZINC00126122

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli cystathionine beta-lyase, PLP-dependent Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania mexicana cystathionine beta-lyase, putative Get druggable targets OG5_136808 All targets in OG5_136808
Leishmania donovani cystathionine beta-lyase, putative Get druggable targets OG5_136808 All targets in OG5_136808
Leishmania infantum cysteine desulfhydrase, putative Get druggable targets OG5_136808 All targets in OG5_136808
Leishmania braziliensis cystathionine beta-lyase, putative Get druggable targets OG5_136808 All targets in OG5_136808
Leishmania major cysteine desulfhydrase Get druggable targets OG5_136808 All targets in OG5_136808
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Brugia malayi protein kinase C II. 0.0505 0.4689 0.4885
Schistosoma mansoni serine/threonine kinase 0.0315 0.2709 0.5777
Echinococcus granulosus neuroglian 0.0105 0.0525 0.0525
Entamoeba histolytica PH domain containing protein kinase, putative 0.0204 0.1557 0.212
Echinococcus granulosus mitogen activated protein kinase 0.0128 0.0769 0.0769
Loa Loa (eye worm) variant SH3 domain-containing protein 0.007 0.016 0.0086
Trichomonas vaginalis STE family protein kinase 0.0178 0.1289 0.1621
Schistosoma mansoni serine/threonine-protein kinase 0.0473 0.4356 0.929
Echinococcus granulosus serine:threonine protein kinase N2 0.0132 0.0806 0.0806
Giardia lamblia Kinase, CMGC CK2 0.0294 0.2497 0.6277
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0209 0.1609 0.219
Loa Loa (eye worm) hypothetical protein 0.0062 0.0082 0.0003
Entamoeba histolytica protein kinase, putative 0.0315 0.2709 0.3687
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0128 0.0769 0.1765
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0066 0.0118 0.0196
Brugia malayi Serine/threonine-protein kinase Pim-3 0.019 0.141 0.1409
Brugia malayi Variant SH3 domain containing protein 0.0073 0.0197 0.0122
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.033 0.2871 0.3438
Entamoeba histolytica protein kinase, putative 0.0209 0.1609 0.219
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0434 0.3953 0.3953
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Loa Loa (eye worm) hypothetical protein 0.0073 0.0193 0.0122
Brugia malayi casein kinase I 0.0066 0.0119 0.004
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0145 0.0943 0.0916
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0073 0.0197 0.042
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0096 0.043 0.043
Schistosoma mansoni nephrin 0.0109 0.0564 0.1202
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0164 0.1136 0.136
Brugia malayi Protein kinase domain containing protein 0.015 0.0996 0.097
Echinococcus multilocularis tyrosine protein kinase Srms 0.0141 0.0903 0.1081
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0088 0.0355 0.0293
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Entamoeba histolytica PH domain containing protein kinase, putative 0.0473 0.4356 0.593
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0066 0.0122 0.028
Loa Loa (eye worm) AGC/PKA protein kinase 0.0427 0.3884 0.4033
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0125 0.0732 0.0692
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0427 0.3884 0.5286
Echinococcus granulosus tyrosine protein kinase HCK 0.0115 0.0632 0.0632
Schistosoma mansoni kinase 0.0073 0.0196 0.0418
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0128 0.0764 0.0915
Brugia malayi Protein kinase domain containing protein 0.0156 0.1061 0.1038
Echinococcus granulosus serine threonine protein kinase nrc 0.0434 0.3953 0.3953
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0059 0.0049 0.0058
Onchocerca volvulus 0.0318 0.2739 0.2818
Schistosoma mansoni serine/threonine protein kinase 0.019 0.141 0.3008
Echinococcus multilocularis casein kinase I alpha 0.0066 0.0119 0.0143
Brugia malayi Protein kinase domain containing protein 0.076 0.7347 0.7703
Schistosoma mansoni serine/threonine protein kinase 0.0505 0.4689 1
Brugia malayi Protein kinase domain containing protein 0.0198 0.1495 0.1498
Plasmodium vivax calcium-dependent protein kinase, putative 0.0066 0.0118 0.0196
Echinococcus granulosus roundabout 2 0.0119 0.0677 0.0677
Trypanosoma brucei casein kinase I, isoform 2 0.0066 0.0119 0.0162
Schistosoma mansoni protein kinase 0.0066 0.0119 0.0254
Echinococcus granulosus mitogen activated protein kinase 14 0.0156 0.1054 0.1054
Trichomonas vaginalis AGC family protein kinase 0.076 0.7347 1
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0077 0.0235 0.0235
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0085 0.0314 0.0314
Giardia lamblia Kinase, CMGC GSK 0.0125 0.0732 0.1765
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0161 0.1114 0.1334
Brugia malayi Protein kinase domain containing protein 0.0315 0.2709 0.2785
Brugia malayi p70 ribosomal S6 kinase beta 0.0721 0.6943 0.7275
Trypanosoma cruzi cdc2-related kinase 3 0.0156 0.1061 0.2435
Entamoeba histolytica protein kinase, putative 0.0115 0.0632 0.086
Entamoeba histolytica PH domain containing protein kinase, putative 0.0466 0.4287 0.5835
Echinococcus granulosus casein kinase I delta 0.0066 0.0119 0.0119
Echinococcus granulosus tyrosine protein kinase Fyn 0.0161 0.1114 0.1114
Loa Loa (eye worm) hypothetical protein 0.033 0.2865 0.2953
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.022 0.1722 0.2062
Echinococcus granulosus serine:threonine protein kinase TAO1 0.022 0.1722 0.1722
Giardia lamblia Kinase, AGC PKA 0.0427 0.3884 0.9823
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0113 0.0609 0.0559
Echinococcus granulosus mitogen activated protein kinase 11 0.0156 0.1054 0.1054
Loa Loa (eye worm) hypothetical protein 0.0089 0.0355 0.0293
Schistosoma mansoni tyrosine kinase 0.0073 0.0197 0.0421
Echinococcus multilocularis cyclin dependent kinase 5 0.0156 0.1061 0.127
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0427 0.3884 0.3884
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0125 0.0732 0.1884
Loa Loa (eye worm) hypothetical protein 0.0065 0.011 0.0034
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0427 0.3884 0.8915
Schistosoma mansoni tyrosine kinase 0.006 0.0056 0.012
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0161 0.1114 0.1334
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0073 0.0195 0.0266
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0161 0.1114 0.1334
Schistosoma mansoni serine/threonine-protein kinase 0.0473 0.4356 0.929
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0314 0.0428
Echinococcus multilocularis cyclin dependent kinase 1 0.0156 0.1061 0.127
Echinococcus granulosus TGF beta receptor type 1 0.01 0.0478 0.0478
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Schistosoma mansoni tyrosine kinase 0.006 0.0056 0.012
Trichomonas vaginalis CMGC family protein kinase 0.0125 0.0732 0.0849
Trichomonas vaginalis CMGC family protein kinase 0.0294 0.2497 0.3291
Loa Loa (eye worm) AUR protein kinase 0.0085 0.0314 0.025
Schistosoma mansoni tyrosine kinase 0.0284 0.2394 0.5106
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.033 0.2871 0.2959
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0059 0.0049 0.0104
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0158 0.1079 0.106
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0066 0.0122 0.0314
Brugia malayi Fes/CIP4 homology domain containing protein 0.0093 0.0405 0.0343
Brugia malayi Serine/threonine-protein kinase SULU 0.022 0.1722 0.1739
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0073 0.0197 0.042
Entamoeba histolytica protein kinase, putative 0.0066 0.0122 0.0166
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0263 0.2167 0.2214
Brugia malayi intracellular kinase 0.0125 0.0732 0.0689
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0125 0.0732 0.1561
Loa Loa (eye worm) CAMK/PKD protein kinase 0.009 0.0367 0.0305
Trichomonas vaginalis AGC family protein kinase 0.0085 0.0314 0.0272
Trypanosoma brucei protein kinase, putative 0.0136 0.0853 0.116
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0066 0.0119 0.0274
Brugia malayi Protein kinase domain containing protein 0.033 0.2871 0.2957
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0427 0.3884 0.8282
Leishmania major protein kinase, putative 0.015 0.0996 0.2565
Entamoeba histolytica protein kinase, putative 0.076 0.7347 1
Schistosoma mansoni hypothetical protein 0.0077 0.0235 0.0501
Brugia malayi Immunoglobulin I-set domain containing protein 0.044 0.4017 0.4172
Brugia malayi MAP kinase sur-1 0.0128 0.0769 0.0728
Echinococcus granulosus tyrosine protein kinase Blk 0.0141 0.0903 0.0903
Echinococcus multilocularis protein kinase c epsilon type 0.0505 0.4689 0.5615
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Schistosoma mansoni protein kinase 0.0294 0.2497 0.5324
Leishmania major protein kinase, putative 0.0066 0.0122 0.0314
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0161 0.1114 0.1334
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0996 0.2124
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0125 0.0732 0.168
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.0978 0.2086
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0769 0.0901
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0156 0.1061 0.2731
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0769 0.1639
Brugia malayi C1-like domain containing protein 0.0137 0.0859 0.0824
Schistosoma mansoni tyrosine kinase 0.0073 0.0197 0.0421
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0066 0.0119 0.0043
Leishmania major folate/biopterin transporter, putative 0.0066 0.0122 0.0314
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0294 0.2497 0.6277
Entamoeba histolytica PH domain containing protein kinase, putative 0.0066 0.0122 0.0166
Echinococcus granulosus Immunoglobulin 0.0085 0.0317 0.0317
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0128 0.0769 0.1979
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0198 0.1495 0.1501
Leishmania major protein kinase A catalytic subunit isoform 2 0.0427 0.3884 1
Loa Loa (eye worm) SRC-1 0.0161 0.1114 0.1098
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0085 0.0317 0.0675
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0066 0.0118 0.017
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0156 0.1061 0.1041
Entamoeba histolytica protein kinase , putative 0.0085 0.0314 0.0428
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0137 0.0859 0.0828
Trichomonas vaginalis CK1 family protein kinase 0.0066 0.0119 0.0002
Brugia malayi serine/threonine-protein kinase 6 0.0085 0.0314 0.0246
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0152 0.1012 0.2607
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0073 0.0196 0.0125
Loa Loa (eye worm) Csnk2b protein 0.0073 0.0195 0.0124
Echinococcus multilocularis death associated protein kinase 1 0.0857 0.8351 1
Trypanosoma cruzi NIMA-related kinase, putative 0.0066 0.0122 0.028
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0148 0.0978 0.095
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.04 0.3599 0.3599
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0769 0.0901
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.1061 0.2262
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0315 0.2709 0.3244
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Brugia malayi Hr1 repeat family protein 0.0446 0.4082 0.4241
Loa Loa (eye worm) AGC/PKA protein kinase 0.0427 0.3884 0.4033
Echinococcus granulosus mitogen activated protein kinase 3 0.0128 0.0769 0.0769
Loa Loa (eye worm) hypothetical protein 0.0126 0.0746 0.0708
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0066 0.0118 0.0196
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0209 0.161 0.161
Schistosoma mansoni protein kinase C mu 0.0137 0.0859 0.1833
Plasmodium vivax protein kinase Crk2 0.0156 0.1061 0.2606
Echinococcus granulosus protein kinase C gamma type 0.0398 0.3581 0.3581
Schistosoma mansoni tyrosine kinase 0.0058 0.0037 0.0078
Echinococcus granulosus insulin receptor 0.016 0.1098 0.1098
Echinococcus granulosus TGF-beta receptor type-1 0.01 0.0478 0.0478
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0209 0.1609 0.1622
Trypanosoma cruzi cdc2-related kinase 1 0.0156 0.1061 0.2435
Leishmania major protein kinase, putative 0.0085 0.0314 0.0809
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Toxoplasma gondii aurora kinase 0.0085 0.0314 0.0452
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.1609 0.3431
Schistosoma mansoni protein kinase 0.0088 0.0355 0.0756
Entamoeba histolytica protein kinase, putative 0.0085 0.0314 0.0428
Echinococcus granulosus casein kinase I alpha 0.0066 0.0119 0.0119
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0164 0.1136 0.1136
Loa Loa (eye worm) hypothetical protein 0.011 0.0574 0.0525
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.2069 0.4413
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0473 0.4356 1
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.1061 0.2262
Echinococcus granulosus protein kinase shaggy 0.0125 0.0732 0.0732
Onchocerca volvulus 0.0077 0.0235 0.0163
Echinococcus granulosus cyclin dependent kinase 1 0.0156 0.1061 0.1061
Schistosoma mansoni protein kinase 0.033 0.2871 0.6122
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0973 0.0945
Loa Loa (eye worm) CAMK/PIM protein kinase 0.019 0.141 0.1412
Giardia lamblia Kinase, STE STE20 0.0178 0.1289 0.319
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0148 0.0978 0.1171
Echinococcus granulosus Glutaredoxin protein 5 0.0407 0.3668 0.3668
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0427 0.3884 0.3884
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0178 0.1289 0.332
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0066 0.0118 0.016
Loa Loa (eye worm) hypothetical protein 0.0066 0.0118 0.0042
Echinococcus granulosus activated cdc42 kinase 1 0.0196 0.1473 0.1473
Brugia malayi Protein kinase domain containing protein 0.016 0.1098 0.1077
Echinococcus granulosus activin receptor type 0.0427 0.3881 0.3881
Trichomonas vaginalis CK1 family protein kinase 0.0066 0.0119 0.0002
Brugia malayi Protein kinase domain containing protein 0.0209 0.1609 0.1619
Entamoeba histolytica casein kinase 1, putative 0.0066 0.0119 0.0162
Schistosoma mansoni serine/threonine protein kinase 0.0427 0.3884 0.8282
Trypanosoma brucei aurora B kinase 0.0085 0.0314 0.0428
Echinococcus multilocularis serine:threonine protein kinase N2 0.0452 0.4144 0.4962
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0073 0.0195 0.0121
Entamoeba histolytica protein kinase 2, putative 0.0434 0.3953 0.5381
Onchocerca volvulus 0.011 0.0574 0.0522
Echinococcus granulosus c src tyrosine kinase 0.0073 0.0197 0.0197
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.1013 0.216
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.009 0.0367 0.0305
Loa Loa (eye worm) hypothetical protein 0.0282 0.2372 0.2431
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0066 0.0122 0.0166
Loa Loa (eye worm) hypothetical protein 0.0148 0.0978 0.0953
Echinococcus multilocularis neuroglian 0.0105 0.0525 0.0629
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0427 0.3884 0.9823
Loa Loa (eye worm) TK/EGFR protein kinase 0.0087 0.0338 0.0275
Echinococcus multilocularis casein kinase i 0.0066 0.0119 0.0143
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0434 0.3953 0.9074
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0077 0.0235 0.0539
Schistosoma mansoni tyrosine kinase 0.0238 0.1911 0.4075
Schistosoma mansoni tyrosine kinase 0.0087 0.0338 0.0721
Brugia malayi serine/threonine kinase 12 0.0085 0.0314 0.0246
Echinococcus multilocularis mitogen activated protein kinase 11 0.0156 0.1054 0.1262
Echinococcus multilocularis dual specificity 0.0209 0.1609 0.1927
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0128 0.0769 0.1107
Leishmania major cysteine desulfhydrase 0.0362 0.3201 0.8243
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0446 0.4074 0.4878
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0118 0.0251
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.01 0.0478 0.0573
Echinococcus multilocularis casein kinase I delta 0.0066 0.0119 0.0143
Brugia malayi Stress-activated protein kinase jnk-1 0.0263 0.2167 0.2211
Plasmodium vivax casein kinase II beta chain, putative 0.0073 0.0195 0.0394
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0196 0.0267
Brugia malayi Tyrosine-protein kinase abl-1 0.013 0.079 0.0751
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0427 0.3884 0.4651
Echinococcus granulosus casein kinase ii subunit beta 0.0073 0.0195 0.0195
Brugia malayi protein kinase C3,putative 0.0075 0.0211 0.0137
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0427 0.3884 0.5286
Echinococcus granulosus tyrosine protein kinase Src42A 0.0116 0.0638 0.0638
Echinococcus multilocularis epidermal growth factor receptor 0.0087 0.0338 0.0405
Echinococcus multilocularis insulin receptor 0.016 0.1098 0.1315
Loa Loa (eye worm) thyroid receptor interactor 0.0093 0.0405 0.0346
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0137 0.0859 0.0824
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0066 0.0122 0.028
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0287 0.2424 0.319
Trichomonas vaginalis AGC family protein kinase 0.0315 0.2709 0.3584
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0066 0.0118 0.0042
Trypanosoma brucei Casein kinase II 0.0294 0.2497 0.3398
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.1079 0.2301
Echinococcus granulosus fibroblast growth factor receptor 4 0.0128 0.0764 0.0764
Schistosoma mansoni rap gtpase-activating protein 0.0077 0.0235 0.0501
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0128 0.0769 0.1765
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0104 0.052 0.0623
Echinococcus multilocularis N chimaerin 0.0073 0.0197 0.0236
Plasmodium vivax unspecified product 0.0294 0.2497 0.6277
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0209 0.1609 0.3693
Echinococcus multilocularis serine:threonine protein kinase N2 0.0132 0.0806 0.0965
Schistosoma mansoni serine/threonine protein kinase 0.0427 0.3884 0.8282
Trypanosoma brucei protein kinase, putative 0.0125 0.0732 0.0996
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0434 0.3953 0.4734
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0085 0.0314 0.0428
Loa Loa (eye worm) AUR protein kinase 0.0085 0.0314 0.025
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.1495 0.3188
Echinococcus multilocularis mitogen activated protein kinase 14 0.0156 0.1054 0.1262
Loa Loa (eye worm) hypothetical protein 0.0085 0.0317 0.0252
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Loa Loa (eye worm) AGC/PKN protein kinase 0.0446 0.4082 0.4243
Echinococcus granulosus activated cdc42 kinase 1 0.0196 0.1473 0.1473
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0427 0.3884 0.3884
Entamoeba histolytica protein kinase, putative 0.076 0.7347 1
Schistosoma mansoni casein kinase II beta subunit 0.0073 0.0195 0.0417
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0427 0.3884 0.4651
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Giardia lamblia Kinase, CMGC CDK 0.0156 0.1061 0.2606
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0178 0.1289 0.296
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0066 0.0122 0.0206
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0427 0.3884 0.5594
Loa Loa (eye worm) hypothetical protein 0.0182 0.1324 0.132
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0156 0.1061 0.2731
Echinococcus granulosus cyclin dependent kinase 9 0.0073 0.0196 0.0196
Trypanosoma cruzi casein kinase, putative 0.0066 0.0119 0.0274
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0427 0.3884 0.8915
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0066 0.0122 0.0166
Loa Loa (eye worm) TK protein kinase 0.0115 0.0632 0.0587
Echinococcus granulosus casein kinase I delta 0.0066 0.0119 0.0119
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0769 0.0901
Brugia malayi Protein kinase domain containing protein 0.0315 0.2709 0.2785
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0087 0.0341 0.0341
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0119 0.0254
Loa Loa (eye worm) hypothetical protein 0.0062 0.0082 0.0003
Schistosoma mansoni tyrosine kinase 0.0087 0.0338 0.0721
Echinococcus granulosus casein kinase ii subunit alpha 0.0294 0.2497 0.2497
Loa Loa (eye worm) hypothetical protein 0.0196 0.1473 0.1478
Trichomonas vaginalis AGC family protein kinase 0.076 0.7347 1
Trypanosoma cruzi casein kinase, putative 0.0066 0.0119 0.0274
Echinococcus granulosus epidermal growth factor receptor 0.0087 0.0338 0.0338
Loa Loa (eye worm) hypothetical protein 0.0138 0.0871 0.084
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0315 0.2709 0.2788
Toxoplasma gondii AGC kinase 0.0427 0.3884 0.5594
Trichomonas vaginalis AGC family protein kinase 0.076 0.7347 1
Plasmodium falciparum glycogen synthase kinase 3 0.0125 0.0732 0.1851
Echinococcus multilocularis myotubularin protein 13 0.0086 0.033 0.0395
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0128 0.0764 0.0764
Entamoeba histolytica PH domain containing protein kinase, putative 0.0473 0.4356 0.593
Brugia malayi P38 map kinase family protein 2 0.0156 0.1054 0.1031
Echinococcus multilocularis transfer RNA-Thr 0.0196 0.1473 0.1763
Brugia malayi Fibronectin type III domain containing protein 0.0089 0.0355 0.029
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.04 0.3599 0.3732
Leishmania major protein kinase A catalytic subunit 0.0427 0.3884 1
Echinococcus granulosus nervana 2 0.0407 0.3668 0.3668
Brugia malayi SRC-1 0.0161 0.1114 0.1095
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0427 0.3884 0.4031
Onchocerca volvulus 0.0282 0.2372 0.2428
Onchocerca volvulus 0.0125 0.0732 0.0689
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.4074 0.8688
Entamoeba histolytica cell division protein kinase 2, putative 0.0164 0.1145 0.1558
Echinococcus multilocularis cyclin dependent kinase 9 0.0073 0.0196 0.0235
Brugia malayi Pleckstrin Homology Domain 0.0086 0.033 0.0263
Brugia malayi Protein kinase domain containing protein 0.055 0.5159 0.5383
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0178 0.1289 0.1755
Entamoeba histolytica protein kinase, putative 0.0066 0.0122 0.0166
Loa Loa (eye worm) hypothetical protein 0.0086 0.033 0.0266
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Loa Loa (eye worm) TK/ABL protein kinase 0.0264 0.2181 0.2229
Brugia malayi RhoGAP domain containing protein 0.0073 0.0197 0.0122
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0314 0.067
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0066 0.0119 0.0043
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0434 0.3953 1
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0066 0.0122 0.028
Echinococcus multilocularis casein kinase ii subunit alpha 0.0294 0.2497 0.299
Brugia malayi Protein kinase c protein 2 0.0159 0.1084 0.1062
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.1061 0.1304
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0315 0.2709 0.2788
Echinococcus granulosus nervana 2 0.0407 0.3668 0.3668
Loa Loa (eye worm) AGC/AKT protein kinase 0.076 0.7347 0.7703
Schistosoma mansoni protein kinase 0.0085 0.0314 0.067
Echinococcus multilocularis 0.0088 0.0355 0.0425
Brugia malayi protein-tyrosine kinase 0.0141 0.0903 0.087
Schistosoma mansoni vesicular amine transporter 0.0085 0.0317 0.0675
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0178 0.1289 0.128
Trichomonas vaginalis AGC family protein kinase 0.0085 0.0314 0.0272
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0434 0.3953 1
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0721 0.6943 0.7276
Echinococcus multilocularis activated cdc42 kinase 1 0.0196 0.1473 0.1763
Schistosoma mansoni protein kinase 0.0179 0.1293 0.2758
Toxoplasma gondii protein kinase domain-containing protein 0.0066 0.0122 0.0176
Entamoeba histolytica protein kinase, putative 0.0125 0.0732 0.0996
Schistosoma mansoni serine/threonine protein kinase 0.022 0.1722 0.3672
Entamoeba histolytica casein kinase, putative 0.0066 0.0119 0.0162
Trichomonas vaginalis CMGC family protein kinase 0.0294 0.2497 0.3291
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.1061 0.1304
Entamoeba histolytica protein kinase, putative 0.0071 0.017 0.0231
Trypanosoma cruzi casein kinase, putative 0.0066 0.0119 0.0274
Echinococcus multilocularis protein tyrosine kinase 0.0284 0.2394 0.2867
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Echinococcus multilocularis Immunoglobulin 0.0085 0.0317 0.0379
Trichomonas vaginalis AGC family protein kinase 0.0085 0.0314 0.0272
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0427 0.3884 0.5286
Loa Loa (eye worm) hypothetical protein 0.0065 0.011 0.0034
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0427 0.3884 0.4651
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0077 0.0235 0.032
Echinococcus multilocularis cyclin dependent kinase 9 0.0081 0.028 0.0335
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.019 0.141 0.1409
Echinococcus multilocularis Glutaredoxin protein 5 0.0407 0.3668 0.4392
Plasmodium falciparum protein serine/threonine kinase-1 0.015 0.0996 0.252
Brugia malayi Variant SH3 domain containing protein 0.007 0.016 0.0083
Loa Loa (eye worm) hypothetical protein 0.0108 0.0555 0.0505
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.04 0.3599 0.431
Loa Loa (eye worm) hypothetical protein 0.0116 0.0638 0.0593
Echinococcus multilocularis roundabout 2 0.0119 0.0677 0.081
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0077 0.0235 0.0281
Trypanosoma cruzi cdc2-related kinase 1 0.0156 0.1061 0.2435
Giardia lamblia Kinase, AGC PKA 0.0434 0.3953 1
Loa Loa (eye worm) hypothetical protein 0.0089 0.0355 0.0293
Schistosoma mansoni cell adhesion molecule 0.0099 0.0468 0.0998
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0066 0.0119 0.0043
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0148 0.0978 0.0978
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0077 0.0235 0.0501
Trypanosoma cruzi cdc2-related kinase 3 0.0156 0.1061 0.2435
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0073 0.0197 0.0421
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.015 0.0996 0.1356
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0077 0.0235 0.0539
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0158 0.1079 0.1057
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0769 0.0901
Loa Loa (eye worm) hypothetical protein 0.0077 0.0235 0.0166
Loa Loa (eye worm) hypothetical protein 0.0065 0.0107 0.0031
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0152 0.1013 0.1213
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0075 0.0211 0.0141
Loa Loa (eye worm) hypothetical protein 0.0169 0.1191 0.1179
Loa Loa (eye worm) hypothetical protein 0.0079 0.0254 0.0186
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0407 0.3668 0.3668
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0145 0.0943 0.0943
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Trypanosoma cruzi casein kinase, putative 0.0066 0.0119 0.0274
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0113 0.0609 0.0559
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.015 0.0996 0.1356
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.0355 0.029
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0125 0.0732 0.1054
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.01 0.0475 0.042
Echinococcus granulosus hypothetical protein 0.0123 0.0711 0.0711
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0156 0.1054 0.2714
Giardia lamblia Kinase, CMGC CDK 0.0156 0.1061 0.2606
Toxoplasma gondii AGC kinase 0.0721 0.6943 1
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0085 0.0314 0.0376
Leishmania major serine/threonine-protein kinase a, putative 0.0066 0.0122 0.0314
Plasmodium vivax casein kinase II beta chain, putative 0.0073 0.0195 0.0394
Entamoeba histolytica protein kinase domain containing protein 0.0209 0.1609 0.219
Brugia malayi Protein kinase domain containing protein 0.0075 0.0211 0.0137
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0073 0.0197 0.0125
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0209 0.1609 0.3693
Trichomonas vaginalis AGC family protein kinase 0.0085 0.0314 0.0272
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.2497 0.3398
Plasmodium falciparum casein kinase II beta chain 0.0073 0.0195 0.0494
Brugia malayi Protein kinase domain containing protein 0.01 0.0475 0.0417
Brugia malayi serine/threonine protein kinase 6 0.0085 0.0314 0.0246
Echinococcus multilocularis mitogen activated protein kinase 14 0.0156 0.1054 0.1262
Trypanosoma cruzi NIMA-related kinase, putative 0.0066 0.0122 0.028
Brugia malayi hypothetical protein 0.0077 0.0235 0.0162
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.1107 0.236
Loa Loa (eye worm) hypothetical protein 0.0085 0.0317 0.0252
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.015 0.0996 0.2287
Echinococcus granulosus casein kinase I alpha 0.0066 0.0119 0.0119
Plasmodium falciparum calcium-dependent protein kinase 2 0.0066 0.0118 0.0298
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0264 0.2181 0.2612
Plasmodium falciparum calcium-dependent protein kinase 5 0.0066 0.0118 0.0298
Echinococcus granulosus dual specificity mitogen activated protein 0.0178 0.1289 0.1289
Entamoeba histolytica protein kinase, putative 0.0066 0.0122 0.0166
Plasmodium falciparum calcium-dependent protein kinase 4 0.0066 0.0118 0.0298
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0116 0.0638 0.0764
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Leishmania major protein kinase, putative 0.015 0.0996 0.2565
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0066 0.0118 0.017
Leishmania major casein kinase, putative 0.0066 0.0119 0.0307
Echinococcus multilocularis aurora kinase A 0.0085 0.0314 0.0376
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0073 0.0195 0.0503
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0073 0.0197 0.0197
Schistosoma mansoni protein kinase 0.0179 0.1293 0.2758
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0294 0.2497 0.2563
Entamoeba histolytica protein kinase, putative 0.0209 0.1609 0.219
Schistosoma mansoni tyrosine kinase 0.016 0.1098 0.2341
Brugia malayi Cam kinase protein 1 0.0066 0.0118 0.0038
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0125 0.0732 0.0692
Trypanosoma cruzi casein kinase, putative 0.0066 0.0119 0.0274
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0125 0.0732 0.0732
Loa Loa (eye worm) IKK protein kinase 0.0968 0.9514 1
Schistosoma mansoni serine/threonine protein kinase 0.04 0.3599 0.7676
Loa Loa (eye worm) hypothetical protein 0.0129 0.0776 0.0739
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Echinococcus multilocularis nervana 2 0.0407 0.3668 0.4392
Echinococcus granulosus protein kinase c epsilon type 0.0505 0.4689 0.4689
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.4074 0.8688
Entamoeba histolytica cell division protein kinase 2, putative 0.0156 0.1061 0.1444
Loa Loa (eye worm) hypothetical protein 0.0077 0.0235 0.0166
Toxoplasma gondii casein kinase I 0.0066 0.0119 0.0172
Brugia malayi hypothetical protein 0.022 0.1722 0.1739
Loa Loa (eye worm) hypothetical protein 0.0096 0.043 0.0372
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0427 0.3884 0.4651
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0161 0.1114 0.1334
Echinococcus multilocularis cyclin dependent kinase 0.0156 0.1061 0.127
Brugia malayi hypothetical protein 0.0089 0.0355 0.029
Entamoeba histolytica protein kinase, putative 0.0085 0.0314 0.0428
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0087 0.034 0.0407
Echinococcus granulosus Protein kinase C brain isozyme 0.0446 0.4074 0.4074
Trichomonas vaginalis AGC family protein kinase 0.0323 0.2793 0.37
Plasmodium falciparum casein kinase 1 0.0066 0.0119 0.0302
Trichomonas vaginalis CMGC family protein kinase 0.0294 0.2497 0.3291
Echinococcus granulosus cyclin dependent kinase 0.0156 0.1061 0.1061
Loa Loa (eye worm) hypothetical protein 0.0116 0.0638 0.0593
Loa Loa (eye worm) hypothetical protein 0.0089 0.0355 0.0293
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0092 0.0392 0.0392
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0118 0.0118
Echinococcus granulosus protein kinase c iota type 0.0362 0.3202 0.3202
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0118 0.0141
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0066 0.0122 0.028
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.015 0.0996 0.2287
Loa Loa (eye worm) TK/FAK protein kinase 0.0287 0.2426 0.2488
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0073 0.0197 0.0236
Entamoeba histolytica protein kinase, putative 0.0066 0.0122 0.0166
Echinococcus multilocularis raf serine:threonine protein kinase 0.0074 0.0208 0.0249
Brugia malayi Protein kinase domain containing protein 0.0287 0.2426 0.2486
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0085 0.0314 0.0428
Loa Loa (eye worm) hypothetical protein 0.0282 0.2372 0.2431
Trichomonas vaginalis CMGC family protein kinase 0.0294 0.2497 0.3291
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0156 0.1061 0.1041
Entamoeba histolytica protein kinase domain containing protein 0.0125 0.0732 0.0996
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0209 0.161 0.1927
Echinococcus granulosus tyrosine protein kinase Src42A 0.0161 0.1114 0.1114
Brugia malayi Protein kinase domain containing protein 0.009 0.0367 0.0302
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0066 0.0118 0.0196
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0128 0.0764 0.0915
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0141 0.0903 0.1081
Loa Loa (eye worm) AUR protein kinase 0.0085 0.0314 0.025
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.022 0.1722 0.1742
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0104 0.052 0.052
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.1061 0.1304
Trypanosoma brucei protein kinase, putative 0.0066 0.0122 0.0166
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0113 0.0609 0.0562
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0179 0.1293 0.1293
Trichomonas vaginalis AGC family protein kinase 0.0315 0.2709 0.3584
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0111 0.0591 0.0543
Entamoeba histolytica hypothetical protein 0.0066 0.0122 0.0166
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Echinococcus multilocularis serine:threonine protein kinase 38 0.0315 0.2709 0.3244
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Entamoeba histolytica hypothetical protein 0.0066 0.0122 0.0166
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.4082 0.8704
Echinococcus granulosus Vam6:Vps39 protein 0.0077 0.0235 0.0235
Echinococcus multilocularis protein kinase c iota type 0.0362 0.3202 0.3834
Loa Loa (eye worm) hypothetical protein 0.0123 0.0711 0.067
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0427 0.3884 0.9825
Trichomonas vaginalis AGC family protein kinase 0.076 0.7347 1
Schistosoma mansoni protein kinase 0.0165 0.1156 0.2466
Echinococcus granulosus NDR protein kinase 0.0315 0.2709 0.2709
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0161 0.1114 0.1334
Loa Loa (eye worm) CAMK/PIM protein kinase 0.019 0.141 0.1412
Entamoeba histolytica hypothetical protein 0.0059 0.0049 0.0066
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.015 0.0996 0.1435
Loa Loa (eye worm) TK/ALK protein kinase 0.055 0.5157 0.5383
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0156 0.1054 0.242
Trichomonas vaginalis CMGC family protein kinase 0.0294 0.2497 0.3291
Loa Loa (eye worm) TK protein kinase 0.0141 0.0903 0.0873
Loa Loa (eye worm) hypothetical protein 0.0085 0.0321 0.0257
Loa Loa (eye worm) gastrulation defective protein 1 0.0133 0.0822 0.0788
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0066 0.0122 0.0176
Echinococcus granulosus casein kinase i 0.0066 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0077 0.0235 0.0166
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0427 0.3884 0.8915
Echinococcus multilocularis mitogen activated protein kinase 0.0128 0.0769 0.0921
Loa Loa (eye worm) TK protein kinase 0.0148 0.0973 0.0948
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0077 0.0235 0.0501
Plasmodium falciparum serine/threonine protein kinase, putative 0.0085 0.0314 0.0795
Trichomonas vaginalis CMGC family protein kinase 0.015 0.0996 0.1215
Onchocerca volvulus 0.0148 0.0978 0.095
Echinococcus multilocularis c src tyrosine kinase 0.0073 0.0197 0.0236
Entamoeba histolytica protein kinase domain containing protein 0.0125 0.0732 0.0996
Echinococcus granulosus serine/threonine protein kinase 0.0473 0.4356 0.4356
Schistosoma mansoni tyrosine kinase 0.006 0.0056 0.012
Schistosoma mansoni tyrosine kinase 0.0087 0.0338 0.0721
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0087 0.034 0.0277
Brugia malayi cyclin-dependent kinase 9 0.0073 0.0196 0.0121
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0118 0.0141
Echinococcus multilocularis casein kinase I alpha 0.0066 0.0119 0.0143
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0073 0.0195 0.0449
Echinococcus multilocularis protein kinase shaggy 0.0125 0.0732 0.0876
Plasmodium vivax serine/threonine kinase-1, putative 0.015 0.0996 0.2441
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0085 0.0314 0.0428
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.015 0.0996 0.2287
Echinococcus multilocularis RNA directed DNA polymerase 0.0079 0.0254 0.0304
Giardia lamblia Kinase, CMGC GSK 0.0125 0.0732 0.1765
Entamoeba histolytica casein kinase, putative 0.0294 0.2497 0.3398
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Echinococcus multilocularis tyrosine protein kinase Abl 0.0154 0.1037 0.1242
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0085 0.0314 0.0698
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0059 0.0049 0.0049
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0066 0.0118 0.0038
Schistosoma mansoni atypical protein kinase C 0.0362 0.3202 0.6828
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0066 0.0122 0.0166
Schistosoma mansoni protein kinase 0.01 0.0478 0.102
Echinococcus granulosus tyrosine protein kinase Src64B 0.0161 0.1114 0.1114
Echinococcus multilocularis serine:threonine protein kinase N2 0.0446 0.4082 0.4887
Loa Loa (eye worm) TK/INSR protein kinase 0.016 0.1098 0.108
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0066 0.0122 0.028
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Giardia lamblia Kinase, CMGC MAPK 0.0128 0.0769 0.186
Echinococcus multilocularis cyclin dependent kinase 1 0.0156 0.1061 0.127
Schistosoma mansoni tyrosine kinase 0.0161 0.1114 0.2376
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0156 0.1054 0.242
Echinococcus multilocularis casein kinase I alpha 0.0066 0.0119 0.0143
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0161 0.1114 0.1334
Giardia lamblia Kinase, CK1 Casein kinase 0.0066 0.0119 0.0199
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0145 0.0943 0.0916
Giardia lamblia Kinase, AGC AKT 0.0113 0.0609 0.1451
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0161 0.1114 0.1114
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0128 0.0769 0.1979
Echinococcus granulosus dual specificity 0.0209 0.1609 0.1609
Loa Loa (eye worm) hypothetical protein 0.0062 0.0082 0.0003
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0118 0.0118
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0066 0.0118 0.0042
Echinococcus granulosus dual specificity protein kinase clk2 0.015 0.0996 0.0996
Echinococcus multilocularis mitogen activated protein kinase 11 0.0156 0.1054 0.1262
Echinococcus multilocularis epidermal growth factor receptor 0.0087 0.0338 0.0405
Toxoplasma gondii AGC kinase 0.0427 0.3884 0.5594
Giardia lamblia Aurora kinase 0.0085 0.0314 0.0698
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0066 0.0122 0.028
Brugia malayi Protein kinase domain containing protein 0.019 0.141 0.1409
Echinococcus granulosus tyrosine protein kinase Fyn 0.0161 0.1114 0.1114
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0085 0.0317 0.0379
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.015 0.0996 0.2287
Echinococcus multilocularis cyclin dependent kinase 19 0.0161 0.1107 0.1325
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0315 0.2709 0.2709
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0128 0.0769 0.1765
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0079 0.0254 0.0304
Echinococcus multilocularis TGF beta receptor type 1 0.01 0.0478 0.0573
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Loa Loa (eye worm) hypothetical protein 0.0427 0.3884 0.4033
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0407 0.3668 0.4392
Echinococcus granulosus serine:threonine protein kinase N2 0.0446 0.4082 0.4082
Trichomonas vaginalis AGC family protein kinase 0.0427 0.3884 0.521
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.04 0.3599 0.3599
Echinococcus granulosus casein kinase I alpha 0.0066 0.0119 0.0119
Entamoeba histolytica hypothetical protein 0.0209 0.1609 0.219
Echinococcus granulosus cyclin dependent kinase 19 0.0161 0.1107 0.1107
Entamoeba histolytica PH domain containing protein kinase, putative 0.0466 0.4287 0.5835
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0161 0.1114 0.1114
Brugia malayi Temporarily assigned gene name protein 59 0.0077 0.0235 0.0162
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.019 0.141 0.141
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Loa Loa (eye worm) hypothetical protein 0.0182 0.1324 0.132
Echinococcus multilocularis nervana 2 0.0407 0.3668 0.4392
Plasmodium falciparum casein kinase 2, alpha subunit 0.0294 0.2497 0.6316
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.04 0.3599 0.4309
Echinococcus multilocularis 0.0123 0.0711 0.0852
Brugia malayi Furin-like cysteine rich region family protein 0.0087 0.0338 0.0272
Plasmodium falciparum casein kinase II beta chain 0.0073 0.0195 0.0494
Schistosoma mansoni protein kinase 0.01 0.0475 0.1013
Trichomonas vaginalis AGC family protein kinase 0.076 0.7347 1
Echinococcus multilocularis rac serine:threonine kinase 0.0473 0.4356 0.5217
Schistosoma mansoni tyrosine kinase 0.019 0.1415 0.3017
Leishmania major protein kinase, putative 0.0066 0.0118 0.0303
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0128 0.0769 0.1046
Loa Loa (eye worm) AGC/NDR protein kinase 0.0315 0.2709 0.2788
Plasmodium falciparum calcium-dependent protein kinase 7 0.0066 0.0122 0.0308
Schistosoma mansoni serine/threonine protein kinase 0.0315 0.2709 0.5777
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0161 0.1114 0.1334
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0145 0.0943 0.0913
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0066 0.0118 0.0118
Echinococcus granulosus tyrosine protein kinase ABL1 0.0264 0.2181 0.2181
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0125 0.0732 0.0876
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0118 0.0141
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0066 0.0122 0.0006
Trichomonas vaginalis STE family protein kinase 0.0178 0.1289 0.1621
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Echinococcus granulosus defective proboscis extension response 0.0085 0.0317 0.0317
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0087 0.0338 0.0338
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0152 0.1013 0.1013
Brugia malayi Protein kinase domain containing protein 0.0968 0.9514 1
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0208 0.0443
Trypanosoma brucei cdc2-related kinase 3 0.0156 0.1061 0.1444
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.019 0.141 0.1689
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0073 0.0195 0.0449
Onchocerca volvulus 0.0968 0.9514 1
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0315 0.2709 0.3244
Entamoeba histolytica protein kinase, putative 0.0066 0.0118 0.016
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0161 0.1107 0.109
Echinococcus multilocularis dual specificity protein kinase clk2 0.015 0.0996 0.1193
Echinococcus granulosus serine:threonine protein kinase N2 0.0165 0.1154 0.1154
Trypanosoma cruzi casein kinase II, putative 0.0294 0.2497 0.5731
Leishmania major protein kinase, putative 0.0066 0.0122 0.0314
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0128 0.0769 0.0732
Echinococcus multilocularis protein KINase family member (kin 25) 0.0092 0.0392 0.0469
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0315 0.2709 0.5777
Echinococcus granulosus epidermal growth factor receptor 0.0087 0.0338 0.0338
Echinococcus granulosus N chimaerin 0.0073 0.0197 0.0197
Plasmodium falciparum calcium-dependent protein kinase 1 0.0066 0.0118 0.0298
Entamoeba histolytica protein kinase, putative 0.0721 0.6943 0.9451
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Echinococcus multilocularis casein kinase I delta 0.0066 0.0119 0.0143
Leishmania major casein kinase II, putative 0.0294 0.2497 0.6428
Schistosoma mansoni vam6/vps39 related 0.0077 0.0235 0.0501
Echinococcus granulosus tyrosine protein kinase Lyn 0.0189 0.1399 0.1399
Schistosoma mansoni tyrosine kinase 0.0092 0.0392 0.0835
Giardia lamblia Kinase, CMGC CLK 0.015 0.0996 0.2441
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0505 0.4689 0.4887
Plasmodium vivax casein kinase 1, putative 0.0066 0.0119 0.0199
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.2167 0.4622
Echinococcus granulosus tyrosine protein kinase Fyn 0.0161 0.1114 0.1114
Echinococcus multilocularis Immunoglobulin 0.0085 0.0317 0.0379
Loa Loa (eye worm) hypothetical protein 0.0597 0.5647 0.5902
Schistosoma mansoni vav2 0.0112 0.06 0.128
Brugia malayi cell division control protein 2 homolog 0.0156 0.1061 0.1038
Echinococcus granulosus protein tyrosine kinase 0.0284 0.2394 0.2394
Schistosoma mansoni protein kinase 0.0178 0.1289 0.2749
Echinococcus granulosus c-Jun N-terminal kinases 0.0263 0.2167 0.2167
Echinococcus multilocularis tyrosine protein kinase Blk 0.0141 0.0903 0.1081
Onchocerca volvulus Tyrosine kinase homolog 0.0365 0.323 0.3338
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0141 0.0903 0.0903
Plasmodium vivax glycogen synthase kinase 3, putative 0.0125 0.0732 0.1765
Brugia malayi Protein kinase domain containing protein 0.0196 0.1473 0.1475
Echinococcus granulosus cyclin dependent kinase 5 0.0156 0.1061 0.1061
Brugia malayi Protein kinase domain containing protein 0.0087 0.034 0.0273
Echinococcus multilocularis serine threonine protein kinase 0.0398 0.3581 0.4288
Schistosoma mansoni tyrosine kinase 0.016 0.1098 0.2341
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0156 0.1061 0.1061
Brugia malayi Protein kinase domain containing protein 0.0161 0.1107 0.1087
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0066 0.0122 0.0166
Loa Loa (eye worm) hypothetical protein 0.0092 0.0392 0.0332
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0066 0.0122 0.0006
Trichomonas vaginalis AGC family protein kinase 0.0353 0.3112 0.4142
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.009 0.0367 0.0305
Echinococcus granulosus aurora kinase A 0.0085 0.0314 0.0314
Trichomonas vaginalis CMGC family protein kinase 0.0294 0.2497 0.3291
Echinococcus granulosus myotubularin protein 13 0.0086 0.033 0.033
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0161 0.1114 0.1334
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0066 0.0118 0.017
Trypanosoma cruzi Protein kinase B 0.0473 0.4356 1
Trichomonas vaginalis CK1 family protein kinase 0.0066 0.0119 0.0002
Brugia malayi bone morphogenetic protein type 1 receptor 0.01 0.0475 0.0417
Echinococcus multilocularis dual specificity mitogen activated protein 0.0178 0.1289 0.1544
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0996 0.2124
Echinococcus granulosus RNA directed DNA polymerase 0.0079 0.0254 0.0254
Toxoplasma gondii CMGC kinase, CK2 family 0.0294 0.2497 0.3596
Echinococcus multilocularis activin receptor type 0.0427 0.3881 0.4648
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0138 0.0871 0.0871
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0066 0.0122 0.028
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0073 0.0195 0.0266
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0156 0.1054 0.1435
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.033 0.2871 0.2871
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.1013 0.216
Toxoplasma gondii ck2 beta subunit 0.0073 0.0195 0.0281
Trichomonas vaginalis AGC family protein kinase 0.076 0.7347 1
Schistosoma mansoni protein kinase 0.0179 0.1293 0.2758
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0315 0.2709 0.2709
Echinococcus multilocularis casein kinase ii subunit beta 0.0073 0.0195 0.0234
Brugia malayi Casein kinase II, alpha chain 0.0294 0.2497 0.256
Plasmodium falciparum protein kinase 5 0.0156 0.1061 0.2683
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0156 0.1054 0.1034
Trichomonas vaginalis casein kinase II beta chain, putative 0.0073 0.0195 0.0107
Entamoeba histolytica p21-activated kinase 0.0066 0.0122 0.0166
Echinococcus granulosus raf serine:threonine protein kinase 0.0074 0.0208 0.0208
Trichomonas vaginalis AGC family protein kinase 0.076 0.7347 1
Trypanosoma cruzi aurora B kinase, putative 0.0085 0.0314 0.0721
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0066 0.0122 0.028
Echinococcus multilocularis mitogen activated protein kinase 3 0.0128 0.0769 0.0921
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0263 0.2167 0.2595
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0179 0.1293 0.1549
Brugia malayi casein kinase 1, delta 0.0066 0.0119 0.004
Brugia malayi Tyrosine-protein kinase abl-1 0.0154 0.1037 0.1013
Loa Loa (eye worm) hypothetical protein 0.0282 0.2372 0.2431
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0209 0.1609 0.4143
Loa Loa (eye worm) CMGC/CLK protein kinase 0.015 0.0996 0.0973
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0196 0.0418
Trichomonas vaginalis STE family protein kinase 0.0178 0.1289 0.1621
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0073 0.0195 0.0266
Schistosoma mansoni tyrosine kinase 0.0161 0.1114 0.2376
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0145 0.0943 0.1129
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0178 0.1289 0.1283
Echinococcus granulosus protein kinase 0.0088 0.0355 0.0355
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0427 0.3884 0.8915
Plasmodium falciparum calcium-dependent protein kinase 3 0.0066 0.0118 0.0298
Echinococcus granulosus tyrosine kinase 0.0141 0.0903 0.0903
Onchocerca volvulus 0.0066 0.0119 0.004
Echinococcus multilocularis tyrosine protein kinase HCK 0.0115 0.0632 0.0757
Loa Loa (eye worm) TK/KIN16 protein kinase 0.044 0.4017 0.4174
Schistosoma mansoni tyrosine kinase 0.0128 0.0764 0.163
Brugia malayi probable protein kinase 0.0165 0.1156 0.1139
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0122 0.0006
Giardia lamblia Casein kinase II beta chain 0.0073 0.0195 0.0394
Echinococcus granulosus cyclin dependent kinase 9 0.0081 0.028 0.028
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0156 0.1061 0.1528
Trichomonas vaginalis CMGC family protein kinase 0.0125 0.0732 0.0849
Trichomonas vaginalis CMGC family protein kinase 0.0294 0.2497 0.3291
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0073 0.0195 0.0266
Loa Loa (eye worm) hypothetical protein 0.0494 0.4576 0.4767
Entamoeba histolytica protein kinase, putative 0.0066 0.0122 0.0166
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0085 0.0317 0.0675
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0128 0.0769 0.1765
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0148 0.0978 0.0953
Trypanosoma brucei rac serine-threonine kinase, putative 0.076 0.7347 1
Trypanosoma brucei cdc2-related kinase 1 0.0156 0.1061 0.1444
Leishmania major protein kinase A catalytic subunit isoform 1 0.0427 0.3884 1
Echinococcus granulosus twitchin 0.0132 0.081 0.081
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0073 0.0195 0.0121
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0073 0.0195 0.0281
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0156 0.1061 0.1041
Brugia malayi Csnk2b protein 0.0073 0.0195 0.0121

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 3.4 uM Inhibition of Escherichia coli CBL ChEMBL. 17300162
IC50 (binding) = 3.4 uM Inhibition of Escherichia coli CBL ChEMBL. 17300162
MIC (functional) = 32 ug ml-1 Antibacterial activity against Escherichia coli ATCC 25922 in presence of methionine ChEMBL. 17300162
MIC (functional) = 32 ug ml-1 Antibacterial activity against Escherichia coli ATCC 25922 in absence of methionine ChEMBL. 17300162
MIC (functional) = 32 ug ml-1 Antibacterial activity against Escherichia coli ATCC 25922 in presence of methionine ChEMBL. 17300162
MIC (functional) = 32 ug ml-1 Antibacterial activity against Escherichia coli ATCC 25922 in absence of methionine ChEMBL. 17300162
MIC (functional) > 128 ug ml-1 Antifungal activity against Candida albicans ATCC 90028 ChEMBL. 17300162
MIC (functional) > 128 ug ml-1 Antifungal activity against Candida albicans ATCC 90028 ChEMBL. 17300162

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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