Detailed information for compound 47416

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 329.369 | Formula: C14H19NO6S
  • H donors: 5 H acceptors: 5 LogP: -0.35 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCC1OC(SCC(=O)Nc2ccccc2)C(C(C1O)O)O
  • InChi: 1S/C14H19NO6S/c16-6-9-11(18)12(19)13(20)14(21-9)22-7-10(17)15-8-4-2-1-3-5-8/h1-5,9,11-14,16,18-20H,6-7H2,(H,15,17)
  • InChiKey: JTMBSMVFQCBNSW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis zinc finger protein Ran binding 0.0307 0.1775 0.177
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0036 0.0037
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0075 0.0393 0.0773
Loa Loa (eye worm) histone methyltransferase 0.001 0.0006 0.0012
Giardia lamblia Hypothetical protein 0.0016 0.0041 1
Brugia malayi B-box zinc finger family protein 0.0016 0.0041 0.008
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Onchocerca volvulus 0.0864 0.5086 1
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0077 0.0151
Loa Loa (eye worm) hypothetical protein 0.0307 0.1775 0.3491
Echinococcus granulosus neuropeptide s receptor 0.046 0.2681 0.2676
Echinococcus granulosus Zinc finger RanBP2 type 0.0307 0.1775 0.177
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0159 0.0301
Schistosoma mansoni hypothetical protein 0.0016 0.0041 0.0043
Echinococcus granulosus E3 ubiquitin protein ligase Bre1 0.0016 0.0041 0.0034
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0274 0.0526
Loa Loa (eye worm) RiNg Finger protein family member 0.0016 0.0041 0.008
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0864 0.5086 1
Treponema pallidum catabolite gene activator (Crp) 0.001 0.0006 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0041 0.0193
Onchocerca volvulus 0.0016 0.0041 0.0067
Treponema pallidum catabolite gene activator 0.001 0.0006 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0041 0.0193
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0312 0.0383
Schistosoma mansoni cpg binding protein 0.003 0.0126 0.015
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0036 0.0037
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0117 0.011
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0304 0.0373
Echinococcus multilocularis tumor protein p63 0.169 1 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.007
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0075 0.0393 0.0387
Onchocerca volvulus 0.0247 0.1419 0.2781
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0304 0.0298
Leishmania major hypothetical protein, conserved 0.0016 0.0041 0.0193
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0304 0.0373
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0016 0.0041 0.0067
Trypanosoma cruzi hypothetical protein, conserved 0.0307 0.1775 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0304 0.0298
Onchocerca volvulus 0.0016 0.0041 0.0067
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0127 0.0151
Echinococcus multilocularis RING finger and transmembrane domain containing protein 0.0016 0.0041 0.0034
Schistosoma mansoni smad1 5 8 and 0.0016 0.0042 0.0045
Giardia lamblia Ser/Thr protein kinase 0.0016 0.0041 1
Onchocerca volvulus 0.0307 0.1775 0.3483
Echinococcus granulosus E3 ubiquitin protein ligase MYLIP 0.0016 0.0041 0.0034
Leishmania major hypothetical protein, conserved 0.0016 0.0041 0.0193
Plasmodium vivax RING zinc finger protein, putative 0.0016 0.0041 0.0067
Plasmodium vivax E3 ubiquitin-protein ligase RNF5, putative 0.0016 0.0041 0.0067
Brugia malayi Hypothetical RING finger protein C16C10.7 in chromosome III 0.0016 0.0041 0.008
Schistosoma mansoni hypothetical protein 0.0167 0.0943 0.1173
Trichomonas vaginalis ankyrin, putative 0.0016 0.0041 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0093 0.0171
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger) containing protein, putative 0.0016 0.0041 0.0193
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0156 0.0149
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0864 0.5086 1
Echinococcus granulosus E3 ubiquitin protein ligase LRSAM1 0.0016 0.0041 0.0034
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0036 0.003
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0013 0.0007
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0036 0.003
Loa Loa (eye worm) hypothetical protein 0.0307 0.1775 0.3491
Echinococcus granulosus microtubule associated protein 2 0.1353 0.7992 0.7991
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0304 0.2305
Schistosoma mansoni peter pan-related 0.0016 0.0041 0.0043
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.001 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.008
Giardia lamblia Ribonuclease 0.0016 0.0041 1
Entamoeba histolytica hypothetical protein 0.0035 0.0156 1
Brugia malayi isocitrate dehydrogenase 0.0016 0.004 0.0079
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0093 0.0491
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0016 0.0041 0.0193
Onchocerca volvulus Protein neuralized homolog 0.0016 0.0041 0.0067
Brugia malayi hypothetical protein 0.0149 0.0836 0.1643
Schistosoma mansoni cpg binding protein 0.003 0.0126 0.015
Leishmania major hypothetical protein, conserved 0.0016 0.0041 0.0193
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0041 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0094 0.2942
Brugia malayi beta-lactamase family protein 0.0036 0.0159 0.0313
Echinococcus granulosus neuropeptide receptor A26 0.046 0.2681 0.2676
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0159 0.0301
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0042 0.0045
Loa Loa (eye worm) hypothetical protein 0.0024 0.0093 0.0183
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0307 0.1775 0.3483
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0159 0.0863
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0159 0.1181
Brugia malayi Smad1 0.0016 0.0042 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0075 0.0393 0.0773
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0307 0.1775 0.177
Brugia malayi hypothetical protein 0.0016 0.0041 0.008
Echinococcus granulosus ring finger protein 170 0.0016 0.0041 0.0034
Mycobacterium ulcerans lipase LipD 0.0036 0.0159 0.5125
Schistosoma mansoni hypothetical protein 0.0016 0.0041 0.0043
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0307 0.1775 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.007 0.0364 0.0704
Brugia malayi beta-lactamase 0.0036 0.0159 0.0313
Echinococcus multilocularis ring finger protein 113a 0.0016 0.0041 0.0034
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0159 0.1181
Brugia malayi hypothetical protein 0.0016 0.0041 0.008
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0864 0.5086 0.5083
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0036 0.007
Loa Loa (eye worm) brahma associated protein 0.0864 0.5086 1
Trypanosoma brucei Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.008
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0093 0.0491
Echinococcus granulosus cpg binding protein 0.003 0.0126 0.012
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0127 0.0121
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Leishmania major hypothetical protein, conserved 0.0016 0.0041 0.0193
Loa Loa (eye worm) hypothetical protein 0.0036 0.0159 0.0313
Giardia lamblia Kinase, NEK 0.0016 0.0041 1
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0864 0.5086 1
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0093 0.0171
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0159 0.1181
Trypanosoma cruzi WLM domain containing protein, putative 0.0307 0.1775 1
Schistosoma mansoni TRABID protein (C64 family) 0.0307 0.1775 0.2215
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0864 0.5086 1
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0864 0.5086 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.004 0.0067
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0015 0.0036 0.003
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0159 0.0301
Brugia malayi hypothetical protein 0.0016 0.0041 0.008
Leishmania major hypothetical protein, conserved 0.0307 0.1775 1
Leishmania major hypothetical protein, conserved 0.0307 0.1775 1
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0159 0.0191
Mycobacterium tuberculosis Conserved protein 0.0036 0.0159 0.1181
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0006 0.0011
Trichomonas vaginalis esterase, putative 0.0036 0.0159 0.0301
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0159 0.0301
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0077 0.0071
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.1299 1
Loa Loa (eye worm) AGC/PKG protein kinase 0.001 0.0006 0.0013
Schistosoma mansoni hypothetical protein 0.0864 0.5086 0.6361
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0094 0.0185
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Schistosoma mansoni hypothetical protein 0.0404 0.2351 0.2936
Trypanosoma brucei SNF2 family N-terminal domain/Ring finger domain containing protein, putative 0.0016 0.0041 0.0193
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0036 0.0058
Plasmodium vivax DNA repair protein RAD5, putative 0.0016 0.0041 0.0067
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0127 0.0151
Schistosoma mansoni smad 0.0016 0.0042 0.0045
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0041 0.0193
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Leishmania major cytochrome p450-like protein 0.0025 0.0094 0.0496
Echinococcus granulosus cell growth regulator with ring finger domain 0.0016 0.0041 0.0034
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0159 0.1181
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0304 1
Onchocerca volvulus 0.003 0.0127 0.0237
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0016 0.0041 0.0067
Echinococcus multilocularis ring finger protein 170 0.0016 0.0041 0.0034
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.004 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0159 0.0863
Brugia malayi brahma associated protein 60 kDa 0.0864 0.5086 1
Leishmania major hypothetical protein, conserved 0.0307 0.1775 1
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0307 0.1775 0.3491
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0036 0.0037
Onchocerca volvulus RING finger protein 141 homolog 0.0016 0.0041 0.0067
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0016 0.0041 0.0034
Plasmodium vivax trophozoite exported protein 1, putative 0.0016 0.0041 0.0067
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0013
Trypanosoma brucei hypothetical protein, conserved 0.0307 0.1775 1
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0307 0.1775 1
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0036 0.003
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0016 0.0041 0.0034
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Trichomonas vaginalis ion channel nompc, putative 0.0016 0.0041 0.0067
Echinococcus multilocularis SWI:SNF matrix associated 0.0864 0.5086 0.5083
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0307 0.1775 0.177
Trypanosoma cruzi hypothetical protein 0.0016 0.0041 0.0193
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0093 0.0171
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.004 0.0067
Trypanosoma cruzi hypothetical protein, conserved 0.0307 0.1775 1
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Brugia malayi RING zinc finger protein 0.0016 0.0041 0.008
Trichomonas vaginalis sex-determining protein fem-1, putative 0.0016 0.0041 0.0067
Giardia lamblia Kinase 0.0016 0.0041 1
Echinococcus multilocularis SWI:SNF matrix associated 0.0864 0.5086 0.5083
Schistosoma mansoni hypothetical protein 0.0011 0.0013 0.0008
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.004 0.0067
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.004 0.0192
Schistosoma mansoni hypothetical protein 0.0016 0.0041 0.0043
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0016 0.0041 0.0067
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0304 0.1684
Loa Loa (eye worm) beta-lactamase 0.0036 0.0159 0.0313
Echinococcus multilocularis neuropeptide receptor A26 0.046 0.2681 0.2676
Echinococcus granulosus RING finger protein 185 0.0016 0.0041 0.0034
Echinococcus multilocularis E3 ubiquitin protein ligase LRSAM1 0.0016 0.0041 0.0034
Loa Loa (eye worm) hypothetical protein 0.0036 0.0159 0.0313
Loa Loa (eye worm) RING finger protein 20 0.0016 0.0041 0.008
Schistosoma mansoni smad1 5 8 and 0.0016 0.0042 0.0045
Leishmania major hypothetical protein, conserved 0.0307 0.1775 1
Trichomonas vaginalis hypothetical protein 0.0016 0.0041 0.0067
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Echinococcus multilocularis geminin 0.0167 0.0943 0.0938
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Leishmania major hypothetical protein, conserved 0.0016 0.0041 0.0193
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0016 0.0041 0.0193
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.004 0.0043
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0159 0.5125
Leishmania major hypothetical protein, conserved 0.0036 0.0159 0.0863
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.004 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Brugia malayi hypothetical protein 0.0016 0.0042 0.0082
Echinococcus granulosus RING finger and transmembrane domain containing protein 0.0016 0.0041 0.0034
Brugia malayi Neuralized family protein 0.0016 0.0041 0.008
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.0036 0.003
Trichomonas vaginalis ankyrin, putative 0.0016 0.0041 0.0067
Toxoplasma gondii ran binding protein 0.0307 0.1775 0.3483
Schistosoma mansoni hypothetical protein 0.0167 0.0943 0.1173
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0077 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0041 0.0193
Brugia malayi brahma associated protein 60 kDa 0.0864 0.5086 1
Plasmodium falciparum E3 ubiquitin-protein ligase RNF5, putative 0.0016 0.0041 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Loa Loa (eye worm) Smad1 0.0016 0.0042 0.0083
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.008
Onchocerca volvulus Putative RING finger protein 207 0.0016 0.0041 0.0067
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0307 0.1775 0.3483
Leishmania major hypothetical protein, conserved 0.0016 0.0041 0.0193
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0159 0.1181
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Giardia lamblia Kinase, NEK 0.0016 0.0041 1
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0041 0.0193
Echinococcus multilocularis 0.0016 0.0041 0.0034
Trypanosoma brucei DNA repair protein, putative 0.0016 0.0041 0.0193
Onchocerca volvulus 0.0307 0.1775 0.3483
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.004 0.0192
Echinococcus multilocularis E3 ubiquitin protein ligase Bre1 0.0016 0.0041 0.0034
Onchocerca volvulus 0.0016 0.0041 0.0067
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.004 0.0034
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.001 0.0006 0.0013
Schistosoma mansoni Smad4 0.0016 0.0042 0.0045
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0094 0.0496
Echinococcus multilocularis Smad4 0.0016 0.0042 0.0036
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0307 0.1775 1
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0156 0.0187
Plasmodium vivax zinc finger protein, putative 0.0016 0.0041 0.0067
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0036 0.0037
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.008
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0127 0.0121
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0304 0.0587
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0864 0.5086 0.5083
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0116 0.0229
Loa Loa (eye worm) hypothetical protein 0.0307 0.1775 0.3491
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.008
Schistosoma mansoni cellular tumor antigen P53 0.0247 0.1419 0.1769
Loa Loa (eye worm) hypothetical protein 0.0065 0.0334 0.0658
Brugia malayi Zinc finger protein 183 homolog 0.0016 0.0041 0.008
Trichomonas vaginalis set domain proteins, putative 0.0235 0.1343 0.2632
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0016 0.0041 0.0067
Giardia lamblia Hypothetical protein 0.0016 0.0041 1
Brugia malayi MH1 domain containing protein 0.0016 0.0042 0.0083
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0159 0.1181
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0036 0.003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0077 0.0151
Giardia lamblia Hypothetical protein 0.0016 0.0041 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0159 0.0153
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Trypanosoma brucei hypothetical protein, conserved 0.0307 0.1775 1
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0015 0.0036 0.003
Leishmania major hypothetical protein, conserved 0.0024 0.0093 0.0491
Leishmania major hypothetical protein, unknown function 0.0016 0.0041 0.0193
Giardia lamblia Hypothetical protein 0.0016 0.0041 1
Treponema pallidum cyclic nucleotide binding protein 0.001 0.0006 0.5
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.008
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Trichomonas vaginalis cell cycle control protein cwf24, putative 0.0016 0.0041 0.0067
Trichomonas vaginalis ankyrin, putative 0.0016 0.0041 0.0067
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Echinococcus granulosus geminin 0.0167 0.0943 0.0938
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0159 0.0153
Schistosoma mansoni hypothetical protein 0.0307 0.1775 0.2215
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Schistosoma mansoni fusion 0.0307 0.1775 0.2215
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0102
Loa Loa (eye worm) hypothetical protein 0.0036 0.0159 0.0313
Mycobacterium leprae Probable lipase LipE 0.0036 0.0159 1
Schistosoma mansoni hypothetical protein 0.0864 0.5086 0.6361
Trypanosoma cruzi hypothetical protein 0.0016 0.0041 0.0193
Schistosoma mansoni zinc finger protein 0.0016 0.0041 0.0043
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.004 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0094 0.0496
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0042 0.0036
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.004 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Leishmania major hypothetical protein, conserved 0.0016 0.0041 0.0193
Giardia lamblia Zinc finger domain 0.0016 0.0041 1
Mycobacterium ulcerans hypothetical protein 0.0036 0.0159 0.5125
Toxoplasma gondii hypothetical protein 0.0016 0.0041 0.0067
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Brugia malayi beta-lactamase family protein 0.0036 0.0159 0.0313
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0307 0.1775 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Onchocerca volvulus 0.0235 0.1343 0.2632
Echinococcus multilocularis dnaJ subfamily B 0.0404 0.2351 0.2346
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0159 0.0301
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0159 0.0313
Brugia malayi Cytochrome P450 family protein 0.0025 0.0094 0.0185
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0013 0.0007
Brugia malayi Cyclic-nucleotide gated cation channel 0.0015 0.0036 0.007
Leishmania major hypothetical protein, conserved 0.0016 0.0041 0.0193
Onchocerca volvulus 0.0307 0.1775 0.3483
Leishmania major hypothetical protein, conserved 0.0016 0.0041 0.0193
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0077 0.0088
Schistosoma mansoni hypothetical protein 0.0864 0.5086 0.6361
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.004 0.0034
Schistosoma mansoni cpg binding protein 0.0028 0.0116 0.0138
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0159 0.1181
Brugia malayi Egg laying defective protein 4 0.001 0.0006 0.0013
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0307 0.1775 1
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0015 0.0036 0.003
Echinococcus granulosus smad 0.0016 0.0042 0.0036
Toxoplasma gondii hypothetical protein 0.0016 0.0041 0.0067
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Plasmodium falciparum RING zinc finger protein, putative 0.0016 0.0041 0.0067
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0159 1
Leishmania major hypothetical protein, conserved 0.0307 0.1775 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0036 0.0037
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.004 0.0263
Schistosoma mansoni voltage-gated potassium channel 0.0082 0.0434 0.0536
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0015 0.0036 0.003
Schistosoma mansoni rnf5 0.0016 0.0041 0.0043
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.008
Onchocerca volvulus 0.0016 0.0041 0.0067
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0127 0.0121
Echinococcus granulosus dnaJ subfamily B 0.0404 0.2351 0.2346
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0307 0.1775 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0159 0.1181
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0159 0.0301
Echinococcus granulosus ring finger protein 113a 0.0016 0.0041 0.0034
Chlamydia trachomatis DNA topoisomerase I 0.0864 0.5086 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0159 0.0191
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0018 0.0014
Leishmania major hypothetical protein, conserved 0.0016 0.0041 0.0193
Brugia malayi MH2 domain containing protein 0.0234 0.1339 0.2633
Loa Loa (eye worm) hypothetical protein 0.0307 0.1775 0.3491
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.1174 0.2309
Plasmodium vivax E3 ubiquitin-protein ligase, putative 0.0016 0.0041 0.0067
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0094 0.0496
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Echinococcus granulosus Smad4 0.0016 0.0042 0.0036
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0159 0.5125
Plasmodium vivax SET domain protein, putative 0.003 0.0127 0.0237
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.001 0.0006 0.0013
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0307 0.1775 1
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Toxoplasma gondii hypothetical protein 0.0016 0.0041 0.0067
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0042 0.0036
Mycobacterium ulcerans beta-lactamase 0.0036 0.0159 0.5125
Brugia malayi Zinc finger, C2H2 type family protein 0.0016 0.0041 0.008
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Leishmania major DNA repair protein-like protein 0.0016 0.0041 0.0193
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0864 0.5086 1
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0307 0.1775 0.3491
Entamoeba histolytica hypothetical protein 0.0035 0.0156 1
Echinococcus multilocularis cpg binding protein 0.003 0.0126 0.012
Trypanosoma brucei predicted zinc finger protein 0.0016 0.0041 0.0193
Entamoeba histolytica hypothetical protein 0.0035 0.0156 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0016 0.0041 0.0067
Brugia malayi Pre-SET motif family protein 0.0206 0.1174 0.2309
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0016 0.0041 0.0067
Schistosoma mansoni hypothetical protein 0.0035 0.0156 0.0187
Schistosoma mansoni microtubule-associated protein tau 0.1353 0.7992 1
Echinococcus multilocularis E3 ubiquitin protein ligase MYLIP 0.0016 0.0041 0.0034
Brugia malayi Pre-SET motif family protein 0.003 0.0127 0.0249
Brugia malayi hypothetical protein 0.0035 0.0156 0.0306
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0127 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Leishmania major hypothetical protein, conserved 0.0016 0.0041 0.0193
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.008
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0036 0.0037
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Brugia malayi hypothetical protein 0.0016 0.0041 0.008
Leishmania major hypothetical protein, conserved 0.0016 0.0041 0.0193
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0094 0.0185
Brugia malayi Isocitrate dehydrogenase 0.0016 0.004 0.0079
Giardia lamblia Hypothetical protein 0.0016 0.0041 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0127 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Giardia lamblia Zinc finger domain 0.0016 0.0041 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0093 0.0171
Schistosoma mansoni smad1 5 8 and 0.0016 0.0042 0.0045
Brugia malayi MH2 domain containing protein 0.0016 0.0042 0.0083
Loa Loa (eye worm) MH2 domain-containing protein 0.0234 0.1339 0.2633
Onchocerca volvulus 0.0016 0.0041 0.0067
Leishmania major hypothetical protein 0.0016 0.0041 0.0193
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.004 0.0034
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Toxoplasma gondii RING zinc finger protein 0.0016 0.0041 0.0067
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Giardia lamblia Hypothetical protein 0.0016 0.0041 1
Echinococcus granulosus E3 ubiquitin protein ligase RNF146 0.0016 0.0041 0.0034
Onchocerca volvulus 0.0149 0.0836 0.1632
Entamoeba histolytica hypothetical protein 0.0035 0.0156 1
Brugia malayi CXXC zinc finger family protein 0.0028 0.0116 0.0229
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0307 0.1775 0.3491
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0042 0.0083
Echinococcus multilocularis SWI:SNF matrix associated 0.0864 0.5086 0.5083
Brugia malayi hypothetical protein 0.0024 0.0093 0.0183
Echinococcus multilocularis neuropeptide s receptor 0.046 0.2681 0.2676
Giardia lamblia E3 ubiquitin ligase for Rad6p required for the ubiquitination of histone H2B 0.0016 0.0041 1
Onchocerca volvulus 0.0028 0.0116 0.0216
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.004 0.0079
Onchocerca volvulus 0.0036 0.0159 0.0301
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0036 0.003
Schistosoma mansoni 60S ribosomal protein L21 0.0012 0.0018 0.0014
Onchocerca volvulus 0.0016 0.0041 0.0067
Schistosoma mansoni peter pan-related 0.0016 0.0041 0.0043
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0304 1
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0042 0.0036
Brugia malayi MH1 domain containing protein 0.0016 0.0042 0.0083
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.003 0.0127 0.0249
Brugia malayi YY1-associated factor 2 0.0307 0.1775 0.3491
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0036 0.003
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0075 0.0393 0.0387
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0801 0.4713 0.471
Echinococcus multilocularis ring and YY1 binding protein 0.0307 0.1775 0.177
Schistosoma mansoni ring finger protein 151 0.0016 0.0041 0.0043
Plasmodium vivax hypothetical protein, conserved 0.0864 0.5086 1
Echinococcus multilocularis microtubule associated protein 2 0.1353 0.7992 0.7991
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0077 0.0071
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0159 0.0313
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0094 0.0185
Trypanosoma cruzi hypothetical protein, conserved 0.0307 0.1775 1
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Brugia malayi hypothetical protein 0.0016 0.0041 0.008
Plasmodium falciparum trophozoite exported protein 1 0.0016 0.0041 0.0067
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0077 0.0088
Toxoplasma gondii hypothetical protein 0.0016 0.0041 0.0067
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0156 0.0149
Loa Loa (eye worm) transcription factor SMAD2 0.0234 0.1339 0.2633
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0077 0.0071
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Trypanosoma cruzi WLM domain containing protein, putative 0.0307 0.1775 1
Giardia lamblia Hypothetical protein 0.0016 0.0041 1
Brugia malayi MH2 domain containing protein 0.0016 0.0042 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Plasmodium falciparum E3 ubiquitin-protein ligase, putative 0.0016 0.0041 0.0067
Schistosoma mansoni inhibitor of apoptosis 1 diap1 0.0016 0.0041 0.0043
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.004 0.0192
Brugia malayi N-terminal motif family protein 0.001 0.0006 0.0013
Echinococcus granulosus SWI:SNF matrix associated 0.0864 0.5086 0.5083
Brugia malayi RING finger protein 20 0.0016 0.0041 0.008
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0307 0.1775 0.3491
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.008
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0042 0.0036
Brugia malayi Cytochrome P450 family protein 0.0025 0.0094 0.0185
Echinococcus granulosus zinc finger protein Ran binding 0.0307 0.1775 0.177
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Toxoplasma gondii Bardet-Biedl syndrome 5, putative 0.0016 0.0041 0.0067
Toxoplasma gondii SWI2/SNF2-containing protein RAD5 0.0016 0.0041 0.0067
Echinococcus granulosus ring and YY1 binding protein 0.0307 0.1775 0.177
Schistosoma mansoni zinc finger protein 0.0307 0.1775 0.2215
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0127 0.0151
Loa Loa (eye worm) hypothetical protein 0.0036 0.0159 0.0313
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0307 0.1775 0.3483
Loa Loa (eye worm) hypothetical protein 0.0307 0.1775 0.3491
Toxoplasma gondii helicase, putative 0.0016 0.0041 0.0067
Onchocerca volvulus 0.0307 0.1775 0.3483
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.008
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0864 0.5086 1
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Brugia malayi SWIB/MDM2 domain containing protein 0.0864 0.5086 1
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0041 0.0193
Echinococcus multilocularis RING finger protein 185 0.0016 0.0041 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0304 1
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.001 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0036 0.0159 0.0313
Chlamydia trachomatis SWIB complex protein 0.0864 0.5086 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0159 0.0863
Plasmodium falciparum zinc finger protein, putative 0.0016 0.0041 0.0067
Schistosoma mansoni RNA binding protein 0.0307 0.1775 0.2215
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0159 0.0313
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0036 0.0058
Schistosoma mansoni brg-1 associated factor 0.0864 0.5086 0.6361
Onchocerca volvulus 0.0036 0.0159 0.0301
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0016 0.0041 0.0067
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0016 0.0041 0.0067
Treponema pallidum cyclic nucleotide binding protein 0.001 0.0006 0.5
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0036 0.007
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0016 0.0041 0.0067
Schistosoma mansoni mind bomb 0.0016 0.0041 0.0043
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0042 0.0083
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.004 0.0034
Onchocerca volvulus 0.0036 0.0159 0.0301
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.004 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0041 0.0067
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0159 0.1181
Loa Loa (eye worm) hypothetical protein 0.0149 0.0836 0.1643
Giardia lamblia Protein 21.1 0.0016 0.0041 1
Toxoplasma gondii ABC1 family protein 0.0036 0.0159 0.0301
Trypanosoma brucei ring finger containing protein 0.0016 0.0041 0.0193
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0307 0.1775 0.177
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.007 0.0364 0.0704
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0093 0.0491
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0041 0.0043
Echinococcus multilocularis smad 0.0016 0.0042 0.0036
Brugia malayi hypothetical protein 0.0016 0.0041 0.008
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0016 0.0041 0.0067
Loa Loa (eye worm) hypothetical protein 0.0247 0.1419 0.279
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0016 0.0041 0.0193
Schistosoma mansoni voltage-gated potassium channel 0.0082 0.0434 0.0536
Leishmania major hypothetical protein, conserved 0.0016 0.0041 0.0193

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 3.6 mM Inhibition of rabbit glycogen phosphorylase B enzyme ChEMBL. 9154968
Log Ki (binding) = 2.444 Affinity of the compound was determined on glycogen phosphorylase(GP) enzyme. ChEMBL. 9435905
Log Ki (binding) = 2.44 mM Inhibitory activity against rabbit muscle glycogen phosphorylase ChEMBL. 9406599

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

3 literature references were collected for this gene.

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