Detailed information for compound 522649

Basic information

Technical information
  • TDR Targets ID: 522649
  • Name: (5Z)-5-[[1-(4-methylphenyl)sulfonylindol-3-yl ]methylidene]-2-sulfanylidene-1,3-thiazolidin -4-one
  • MW: 414.521 | Formula: C19H14N2O3S3
  • H donors: 1 H acceptors: 3 LogP: 4.47 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: S=C1NC(=O)/C(=C/c2cn(c3c2cccc3)S(=O)(=O)c2ccc(cc2)C)/S1
  • InChi: 1S/C19H14N2O3S3/c1-12-6-8-14(9-7-12)27(23,24)21-11-13(15-4-2-3-5-16(15)21)10-17-18(22)20-19(25)26-17/h2-11H,1H3,(H,20,22,25)/b17-10-
  • InChiKey: CNSLKOTZZFTOSZ-YVLHZVERSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (5Z)-5-[[1-(p-tolylsulfonyl)indol-3-yl]methylene]-2-thioxo-thiazolidin-4-one
  • (5Z)-5-[[1-(p-tolylsulfonyl)-3-indolyl]methylene]-2-thioxo-4-thiazolidinone
  • (5Z)-2-thioxo-5-[(1-tosylindol-3-yl)methylene]thiazolidin-4-one
  • 5-[[1-(4-methylphenyl)sulfonylindol-3-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
  • 5-[[1-(4-methylphenyl)sulfonylindol-3-yl]methylene]-2-thioxo-thiazolidin-4-one
  • (5Z)-5-[[1-(4-methylphenyl)sulfonylindol-3-yl]methylene]-2-thioxo-thiazolidin-4-one
  • 5-[[1-(4-methylphenyl)sulfonyl-3-indolyl]methylene]-2-thioxo-4-thiazolidinone
  • (5Z)-5-[[1-(4-methylphenyl)sulfonyl-3-indolyl]methylene]-2-thioxo-4-thiazolidinone
  • STK114510

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glycogen synthase kinase 3 beta Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi intracellular kinase Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus granulosus glycogen synthase kinase 3 beta Get druggable targets OG5_126888 All targets in OG5_126888
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Giardia lamblia Kinase, CMGC GSK Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Loa Loa (eye worm) CMGC/GSK protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Giardia lamblia Kinase, CMGC GSK Get druggable targets OG5_126888 All targets in OG5_126888
Babesia bovis protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans second truncated form of RIM11 Serine/threonine protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus granulosus protein kinase shaggy Get druggable targets OG5_126888 All targets in OG5_126888
Theileria parva glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania braziliensis protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus multilocularis glycogen synthase kinase 3 beta Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium berghei glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma cruzi glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans second truncated form of RIM11 Serine/threonine protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Neospora caninum hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium falciparum glycogen synthase kinase 3 Get druggable targets OG5_126888 All targets in OG5_126888
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Onchocerca volvulus Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium knowlesi glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium vivax glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium yoelii Protein kinase domain, putative Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania mexicana protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma japonicum ko:K08822 glycogen synthase kinase 3 alpha, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma brucei gambiense protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania donovani glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus multilocularis protein kinase shaggy Get druggable targets OG5_126888 All targets in OG5_126888
Loa Loa (eye worm) CMGC/GSK protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania infantum glycogen synthase kinase 3 Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans Serine/threonine protein kinase required for induction of IME2 by Ime1p Get druggable targets OG5_126888 All targets in OG5_126888
Cryptosporidium parvum hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) TK/ROR protein kinase 0.01 0.0433 0.0491
Echinococcus granulosus neuropeptide receptor 0.0015 0.001 0.0004
Toxoplasma gondii PAN/Apple domain-containing protein 0.008 0.0336 0.0742
Brugia malayi Calcium binding EGF domain containing protein 0.0037 0.0121 0.014
Schistosoma mansoni sex comb on midleg homolog 0.0044 0.0155 0.0147
Brugia malayi Serotonin receptor 0.0015 0.001 0.0012
Echinococcus granulosus Nicastrin 0.011 0.0482 0.0873
Onchocerca volvulus 0.0051 0.0189 0.2281
Echinococcus multilocularis g protein coupled receptor 0.0015 0.001 0.0004
Loa Loa (eye worm) PAN domain-containing protein 0.008 0.0336 0.0379
Brugia malayi intracellular kinase 0.0058 0.0225 0.026
Toxoplasma gondii microneme protein MIC4 0.008 0.0336 0.0742
Toxoplasma gondii HEAT repeat-containing protein 0.0027 0.0068 0.0135
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.001 0.0002
Echinococcus granulosus neurogenic locus notch protein 0.0032 0.0096 0.0162
Brugia malayi TAR-binding protein 0.0045 0.0161 0.0186
Brugia malayi Presenilin spe-4 0.0079 0.0328 0.0379
Echinococcus granulosus tumor protein p63 0.0312 0.1494 0.2736
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0002
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0077 0.032 0.3376
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0045 0.0161 0.0177
Loa Loa (eye worm) hypothetical protein 0.002 0.0037 0.0034
Schistosoma mansoni tar DNA-binding protein 0.0045 0.0161 0.0153
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.001 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.001 0.0002
Brugia malayi AKH receptor 0.0015 0.001 0.0012
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0051 0.0189 0.0181
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Toxoplasma gondii subtilisin SUB12 0.008 0.0336 0.0742
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Echinococcus granulosus fibropellin Ia 0.0032 0.0096 0.0162
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.001 0.0004
Echinococcus granulosus nicalin 0.004 0.0136 0.0236
Echinococcus multilocularis neuropeptide receptor 0.0015 0.001 0.0004
Echinococcus multilocularis neurogenic locus notch protein 4 0.0032 0.0096 0.0162
Schistosoma mansoni hypothetical protein 0.0096 0.0415 0.0407
Schistosoma mansoni hypothetical protein 0.0032 0.0096 0.0088
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Brugia malayi Importin beta-1 subunit 0.0027 0.0068 0.0078
Echinococcus granulosus notch 0.0032 0.0096 0.0162
Onchocerca volvulus 0.0018 0.0025 0.0188
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0028
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.001 0.0004
Leishmania major hypothetical protein, conserved 0.002 0.0036 0.0004
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.001 0.0003
Loa Loa (eye worm) hypothetical protein 0.008 0.0336 0.0379
Onchocerca volvulus Slit protein homolog 0.0032 0.0096 0.1089
Trichomonas vaginalis penicillin-binding protein, putative 0.0027 0.0072 0.0383
Brugia malayi PAN domain containing protein 0.008 0.0336 0.0388
Entamoeba histolytica hypothetical protein 0.0022 0.0043 0.0097
Onchocerca volvulus 0.008 0.0336 0.4149
Loa Loa (eye worm) hypothetical protein 0.008 0.0336 0.0379
Echinococcus granulosus snurportin 1 0.0284 0.1355 0.248
Onchocerca volvulus 0.0027 0.0072 0.0781
Echinococcus multilocularis neuropeptide receptor A26 0.0015 0.001 0.0004
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.001 0.0004
Leishmania major hypothetical protein, conserved 0.0063 0.0252 0.0254
Loa Loa (eye worm) hypothetical protein 0.0051 0.0189 0.021
Schistosoma mansoni hypothetical protein 0.0227 0.1071 0.1064
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.001 0.0003
Toxoplasma gondii LsmAD domain-containing protein 0.002 0.0036 0.0063
Brugia malayi hypothetical protein 0.0079 0.0328 0.0379
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0058 0.0225 0.0399
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Schistosoma mansoni notch 0.0032 0.0096 0.0088
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.001 0.0002
Echinococcus granulosus hypothetical protein 0.0015 0.001 0.0004
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.001 0.0004
Schistosoma mansoni amine GPCR 0.0015 0.001 0.0002
Brugia malayi Transcription factor IIA, alpha/beta subunit family protein 0.0139 0.063 0.0728
Schistosoma mansoni ran 0.002 0.0033 0.0025
Echinococcus multilocularis g protein coupled receptor 0.0015 0.001 0.0004
Schistosoma mansoni cercarial elastase (S01 family) 0.0051 0.0189 0.0181
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0072 0.0045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0065 0.0261 0.0254
Brugia malayi Trypsin family protein 0.0051 0.0189 0.0219
Echinococcus granulosus tar DNA binding protein 0.0045 0.0161 0.0282
Entamoeba histolytica hypothetical protein 0.0059 0.0229 0.1917
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.001 0.0004
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0031 0.0091 0.0105
Echinococcus multilocularis somatostatin receptor 0.0015 0.001 0.0004
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.1101 0.5439 0.6281
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Plasmodium falciparum cysteine repeat modular protein 1 0.0096 0.0415 1
Brugia malayi Intermediate filament tail domain containing protein 0.002 0.0037 0.0043
Schistosoma mansoni opsin-like receptor 0.0015 0.001 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.001 0.0002
Plasmodium vivax aspartyl proteinase, putative 0.0019 0.0032 0.0597
Schistosoma mansoni tfiia large subunit 0.0139 0.063 0.0622
Echinococcus multilocularis potassium voltage gated channel protein 0.0051 0.0189 0.0334
Brugia malayi RNA binding protein 0.0045 0.0161 0.0186
Echinococcus granulosus Mastin 0.0115 0.0508 0.0922
Brugia malayi Presenilin spe-4 0.0079 0.0328 0.0379
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0085 0.0362 0.0354
Echinococcus granulosus g protein coupled receptor 0.0015 0.001 0.0004
Plasmodium vivax ataxin-2 like protein, putative 0.002 0.0036 0.0685
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0058 0.0225 0.0399
Echinococcus granulosus geminin 0.0227 0.1071 0.1958
Schistosoma mansoni hypothetical protein 0.0227 0.1071 0.1064
Trypanosoma brucei Presenilin enhancer-2 subunit of gamma secretase, putative 0.0063 0.0252 0.0254
Echinococcus multilocularis protein jagged 1 0.0032 0.0096 0.0162
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Plasmodium falciparum plasmepsin IV 0.0019 0.0032 0.0597
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0065 0.0261 0.0254
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0051 0.0189 0.0181
Echinococcus granulosus g protein coupled receptor 0.0015 0.001 0.0004
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.0225 0.1874
Echinococcus multilocularis fibrillin 1 0.008 0.0337 0.0605
Echinococcus multilocularis Nicastrin 0.011 0.0482 0.0873
Loa Loa (eye worm) hypothetical protein 0.0108 0.0474 0.0539
Loa Loa (eye worm) hypothetical protein 0.008 0.0336 0.0379
Trypanosoma cruzi Aph-1 protein, putative 0.0429 0.208 0.2374
Schistosoma mansoni lamin 0.002 0.0037 0.0029
Brugia malayi larval opioid receptor 0.0015 0.001 0.0012
Plasmodium falciparum thioredoxin reductase 0.0034 0.0104 0.2356
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0065 0.0261 0.0302
Brugia malayi SEA domain containing protein 0.0018 0.0025 0.0029
Schistosoma mansoni cercarial elastase (S01 family) 0.0051 0.0189 0.0181
Loa Loa (eye worm) thioredoxin reductase 0.0034 0.0104 0.0111
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0176 0.0815 0.1486
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.001 0.0004
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.002 0.0033 0.0056
Entamoeba histolytica hypothetical protein 0.0059 0.0229 0.1917
Brugia malayi PAN domain containing protein 0.008 0.0336 0.0388
Loa Loa (eye worm) hypothetical protein 0.0031 0.0091 0.0096
Brugia malayi neuropeptide F receptor 0.0015 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Echinococcus granulosus neuropeptide receptor 0.0015 0.001 0.0004
Schistosoma mansoni egf-like domain protein 0.008 0.0337 0.0329
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Schistosoma mansoni slit 0.0032 0.0096 0.0088
Schistosoma mansoni cercarial elastase (S01 family) 0.0051 0.0189 0.0181
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0177 0.082 0.0813
Toxoplasma gondii PAN domain-containing protein 0.008 0.0336 0.0742
Brugia malayi PAN domain containing protein 0.008 0.0336 0.0388
Brugia malayi hypothetical protein 0.002 0.0036 0.0041
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0186 0.0866 0.0858
Brugia malayi G protein-coupled receptor F59B2.13 0.0015 0.001 0.0012
Echinococcus multilocularis serotonin receptor 0.0015 0.001 0.0004
Echinococcus multilocularis tumor protein p63 0.0312 0.1494 0.2736
Brugia malayi hypothetical protein 0.0015 0.001 0.0012
Leishmania major importin beta-1 subunit, putative 0.0022 0.0043 0.0012
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.001 0.0004
Echinococcus granulosus tfiia large subunit 0.0139 0.063 0.1145
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0072 0.0045
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.001 0.0004
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0225 0.1058 0.1189
Toxoplasma gondii hypothetical protein 0.008 0.0336 0.0742
Echinococcus multilocularis transmembrane protease serine 3 0.0051 0.0189 0.0334
Loa Loa (eye worm) intermediate filament protein 0.002 0.0037 0.0034
Loa Loa (eye worm) hypothetical protein 0.0172 0.0795 0.091
Loa Loa (eye worm) hypothetical protein 0.0027 0.0072 0.0074
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.001 0.0002
Echinococcus multilocularis lamin 0.002 0.0037 0.0054
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0015 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Toxoplasma gondii thioredoxin reductase 0.0034 0.0104 0.0217
Leishmania major C-8 sterol isomerase-like protein 0.1744 0.8654 1
Onchocerca volvulus 0.0032 0.0096 0.1089
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Loa Loa (eye worm) notch protein 0.0032 0.0096 0.0102
Brugia malayi Trypsin family protein 0.0051 0.0189 0.0219
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0175 0.0809 1
Echinococcus multilocularis neuropeptide s receptor 0.0015 0.001 0.0004
Trichomonas vaginalis D-aminoacylase, putative 0.0027 0.0072 0.0383
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.001 0.0002
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.001 0.0004
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0051 0.0189 0.0334
Loa Loa (eye worm) gamma-secretase subunit pen-2 0.0211 0.0989 0.1135
Schistosoma mansoni opsin-like receptor 0.0015 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Brugia malayi Trypsin family protein 0.0051 0.0189 0.0219
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Loa Loa (eye worm) hypothetical protein 0.0051 0.0189 0.021
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0065 0.0261 0.0467
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Brugia malayi hypothetical protein 0.011 0.0482 0.0557
Schistosoma mansoni hypothetical protein 0.0051 0.0189 0.0181
Echinococcus granulosus presenilin 0.0225 0.1058 0.1934
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0115 0.0508 0.0501
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.002
Brugia malayi PAN domain containing protein 0.008 0.0336 0.0388
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Onchocerca volvulus 0.008 0.0336 0.4149
Loa Loa (eye worm) PAN domain-containing protein 0.008 0.0336 0.0379
Toxoplasma gondii microneme protein MIC17B 0.008 0.0336 0.0742
Echinococcus granulosus thioredoxin glutathione reductase 0.0034 0.0104 0.0177
Onchocerca volvulus 0.0027 0.0072 0.0781
Onchocerca volvulus 0.008 0.0336 0.4149
Loa Loa (eye worm) hypothetical protein 0.0051 0.0189 0.021
Brugia malayi Dopamine receptor protein 2 0.0015 0.001 0.0012
Plasmodium vivax plasmepsin IV, putative 0.0019 0.0032 0.0597
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.001 0.0004
Schistosoma mansoni sex comb on midleg homolog 0.0044 0.0155 0.0147
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0072 0.0074
Schistosoma mansoni transcription factor LCR-F1 0.0059 0.0229 0.0222
Echinococcus multilocularis Tolloid protein 1 0.0085 0.0362 0.0652
Echinococcus granulosus fmrfamide receptor 0.0015 0.001 0.0004
Echinococcus multilocularis neurogenic locus notch protein 0.0032 0.0096 0.0162
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.001 0.0004
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.001 0.0002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0051 0.0189 0.0181
Toxoplasma gondii kringle domain-containing protein 0.0096 0.0415 0.0921
Echinococcus multilocularis slit 2 protein 0.0032 0.0096 0.0162
Echinococcus granulosus tfiia large subunit 0.0139 0.063 0.1145
Brugia malayi Presenilin-like protein At2g29900 0.0079 0.0328 0.0379
Schistosoma mansoni opsin-like receptor 0.0015 0.001 0.0002
Brugia malayi RNA, U transporter 1 0.0076 0.0313 0.0362
Trichomonas vaginalis Nicastrin precursor, putative 0.011 0.0482 0.4387
Echinococcus granulosus somatostatin receptor 0.0015 0.001 0.0004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0065 0.0261 0.0467
Onchocerca volvulus 0.0032 0.0096 0.1089
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.001 0.0004
Mycobacterium ulcerans hypothetical protein 0.0051 0.0189 1
Brugia malayi hypothetical protein 0.0015 0.001 0.0012
Brugia malayi PAN domain containing protein 0.008 0.0336 0.0388
Trypanosoma brucei C-8 sterol isomerase, putative 0.1744 0.8654 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0189 0.021
Loa Loa (eye worm) hypothetical protein 0.008 0.0336 0.0379
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0015 0.001 0.0012
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.008 0.0337 0.0389
Loa Loa (eye worm) transcription factor IIA 0.0139 0.063 0.0719
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.002 0.0033 0.0608
Echinococcus granulosus sex peptide receptor 0.0015 0.001 0.0004
Trichomonas vaginalis D-aminoacylase, putative 0.0027 0.0072 0.0383
Loa Loa (eye worm) hypothetical protein 0.005 0.0186 0.0206
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0046 0.0163 0.0179
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Onchocerca volvulus 0.008 0.0336 0.4149
Brugia malayi GCC2 and GCC3 family protein 0.0044 0.0156 0.0181
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0225 0.1878
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.001 0.0004
Schistosoma mansoni hypothetical protein 0.0032 0.0096 0.0088
Loa Loa (eye worm) hypothetical protein 0.0044 0.0156 0.0172
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.005 0.0185 0.0327
Brugia malayi Trypsin-like protease protein 5 0.0051 0.0189 0.0219
Echinococcus multilocularis tar DNA binding protein 0.0045 0.0161 0.0282
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Loa Loa (eye worm) DOMON domain-containing protein 0.0018 0.0025 0.002
Brugia malayi Protein kinase domain containing protein 0.01 0.0433 0.05
Loa Loa (eye worm) RNA binding protein 0.0045 0.0161 0.0177
Loa Loa (eye worm) PAN domain-containing protein 0.008 0.0336 0.0379
Toxoplasma gondii microneme protein MIC17A 0.008 0.0336 0.0742
Echinococcus multilocularis microtubule associated protein 2 0.0637 0.3119 0.5728
Schistosoma mansoni intermediate filament proteins 0.002 0.0037 0.0029
Brugia malayi Calcium binding EGF domain containing protein 0.0032 0.0096 0.0111
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Trypanosoma cruzi importin beta-1 subunit, putative 0.0022 0.0043 0.0012
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.008 0.0337 0.038
Entamoeba histolytica protein kinase, putative 0.0058 0.0225 0.1874
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.001 0.0004
Onchocerca volvulus 0.0018 0.0025 0.0188
Trypanosoma brucei Aph-1 protein, putative 0.0429 0.208 0.2374
Plasmodium vivax glutathione reductase, putative 0.0034 0.0104 0.2356
Echinococcus multilocularis beta LACTamase domain containing family member 0.0027 0.0072 0.0117
Brugia malayi hypothetical protein 0.0079 0.0328 0.0379
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Echinococcus multilocularis neurogenic locus protein delta 0.0032 0.0096 0.0162
Echinococcus multilocularis thioredoxin glutathione reductase 0.0034 0.0104 0.0177
Toxoplasma gondii PAN domain-containing protein 0.008 0.0336 0.0742
Toxoplasma gondii microneme protein MIC17C 0.008 0.0336 0.0742
Onchocerca volvulus 0.008 0.0336 0.4149
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.001 0.0004
Onchocerca volvulus 0.008 0.0336 0.4149
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0051 0.0189 0.0334
Echinococcus multilocularis fmrfamide receptor 0.0015 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0044 0.0155 0.017
Brugia malayi gamma-secretase subunit aph-1 0.1101 0.5439 0.6285
Brugia malayi G-protein coupled receptor 0.0015 0.001 0.0012
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.001 0.0004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.001 0.0002
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0022 0.0043 0.0101
Brugia malayi Serotonin receptor 0.0015 0.001 0.0012
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0511 0.2487 0.2874
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0058 0.0225 0.0223
Schistosoma mansoni hypothetical protein 0.011 0.0482 0.0475
Echinococcus multilocularis protein jagged 1 0.0032 0.0096 0.0162
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.001 0.0002
Onchocerca volvulus Putative cubilin 0.0037 0.0121 0.1409
Schistosoma mansoni cell polarity protein 0.0032 0.0096 0.0088
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.001 0.0003
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0104 0.0083
Toxoplasma gondii hypothetical protein 0.0063 0.0252 0.0552
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.001 0.0004
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0225 0.1058 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0284 0.1355 0.1558
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.001 0.0004
Plasmodium vivax importin-beta 2, putative 0.0027 0.0068 0.147
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0065 0.0261 0.0467
Schistosoma mansoni cathepsin D (A01 family) 0.0057 0.0222 0.0214
Echinococcus multilocularis fibropellin Ia 0.0032 0.0096 0.0162
Schistosoma mansoni cercarial elastase (S01 family) 0.0051 0.0189 0.0181
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0085 0.0362 0.0409
Toxoplasma gondii hypothetical protein 0.008 0.0336 0.0742
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.001 0.0004
Brugia malayi notch-like transmembrane receptor 0.0032 0.0096 0.0111
Brugia malayi Calcium binding EGF domain containing protein 0.008 0.0337 0.0389
Echinococcus granulosus tissue type plasminogen activator 0.0096 0.0415 0.075
Echinococcus granulosus Tolloid protein 1 0.0085 0.0362 0.0652
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.001 0.0002
Echinococcus multilocularis allatostatin A receptor 0.0015 0.001 0.0004
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.005 0.0185 0.0214
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.002 0.0037 0.0034
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0086 0.0364 1
Entamoeba histolytica hypothetical protein 0.0059 0.0229 0.1917
Leishmania major presenilin-like aspartic peptidase, putative,presenilin-like aspartic peptidase, clan AD, family A22A, putative 0.0225 0.1058 0.1189
Schistosoma mansoni neuropeptide receptor 0.0015 0.001 0.0002
Schistosoma mansoni neuropeptide receptor 0.0015 0.001 0.0002
Brugia malayi gamma-secretase subunit pen-2 0.0211 0.0989 0.1143
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.001 0.0003
Loa Loa (eye worm) hypothetical protein 0.011 0.0482 0.0549
Schistosoma mansoni cercarial elastase (S01 family) 0.0051 0.0189 0.0181
Brugia malayi hypothetical protein 0.0015 0.001 0.0012
Schistosoma mansoni histamine h1 receptor 0.0015 0.001 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.001 0.0002
Brugia malayi follicle stimulating hormone receptor 0.0015 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0051 0.0189 0.021
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.002 0.0033 0.0038
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.001 0.0004
Brugia malayi putative neuropeptide receptor NPR1 0.0015 0.001 0.0012
Brugia malayi EGF-like domain containing protein 0.0032 0.0096 0.0111
Brugia malayi Kringle domain containing protein 0.0096 0.0415 0.048
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.001 0.0004
Brugia malayi Dopamine receptor 0.0015 0.001 0.0012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.001 0.0002
Plasmodium vivax glycogen synthase kinase 3, putative 0.0058 0.0225 0.5329
Brugia malayi beta-lactamase family protein 0.0027 0.0072 0.0083
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.001 0.0004
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0044 0.0155 0.1842
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0077 0.032 0.3376
Trichomonas vaginalis importin beta-1, putative 0.0022 0.0043 0.0101
Leishmania major hypothetical protein, conserved 0.0096 0.0415 0.0443
Brugia malayi hypothetical protein 0.0015 0.001 0.0012
Onchocerca volvulus 0.005 0.0186 0.2239
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0059 0.0229 0.0408
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Schistosoma mansoni notch 0.0032 0.0096 0.0088
Echinococcus multilocularis neuropeptide receptor 0.0015 0.001 0.0004
Echinococcus multilocularis presenilin 0.0225 0.1058 0.1934
Onchocerca volvulus 0.002 0.0037 0.0343
Echinococcus multilocularis tfiia large subunit 0.0139 0.063 0.1145
Onchocerca volvulus Neurogenic locus notch homolog 0.0032 0.0096 0.1089
Loa Loa (eye worm) hypothetical protein 0.005 0.0185 0.0205
Echinococcus multilocularis SAM and MBT domain containing protein 0.0044 0.0155 0.027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.001 0.0002
Brugia malayi PAN domain containing protein 0.008 0.0336 0.0388
Brugia malayi hypothetical protein 0.0015 0.001 0.0012
Schistosoma mansoni hypothetical protein 0.0032 0.0096 0.0088
Brugia malayi EGF-like domain containing protein 0.0032 0.0096 0.0111
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0015 0.001 0.0003
Schistosoma mansoni amine GPCR 0.0015 0.001 0.0002
Schistosoma mansoni notch 0.0032 0.0096 0.0088
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.001 0.0004
Schistosoma mansoni notch 0.0032 0.0096 0.0088
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0022 0.0043 0.0101
Brugia malayi Calcitonin receptor-like protein seb-1 0.0031 0.0091 0.0105
Plasmodium falciparum plasmepsin II 0.0019 0.0032 0.0597
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Echinococcus multilocularis fmrfamide receptor 0.0015 0.001 0.0004
Toxoplasma gondii 1,3(4)-beta-glucanase 0.008 0.0336 0.0742
Onchocerca volvulus 0.0172 0.0795 1
Echinococcus multilocularis gamma secretase subunit aph 1 0.1101 0.5439 1
Brugia malayi G protein-coupled receptor 0.0015 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.008 0.0337 0.038
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0077 0.032 0.3376
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.001 0.0004
Schistosoma mansoni septate junction protein 0.0032 0.0096 0.0088
Echinococcus multilocularis g protein coupled receptor 0.0015 0.001 0.0004
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.001 0.0004
Echinococcus granulosus orexin receptor type 2 0.0015 0.001 0.0004
Plasmodium vivax thioredoxin reductase, putative 0.0034 0.0104 0.2356
Echinococcus granulosus lamin 0.002 0.0037 0.0054
Brugia malayi Tachykinin-like peptides receptor 99D 0.0015 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0098 0.0422 0.0479
Plasmodium falciparum glutathione reductase 0.0034 0.0104 0.2356
Brugia malayi RNA recognition motif domain containing protein 0.0045 0.0161 0.0186
Brugia malayi hypothetical protein 0.0015 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Schistosoma mansoni biogenic amine receptor 0.0015 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Brugia malayi hypothetical protein 0.0015 0.001 0.0012
Toxoplasma gondii EGF family domain-containing protein 0.0032 0.0096 0.0199
Schistosoma mansoni hypothetical protein 0.027 0.1286 0.1279
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.001 0.0004
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0086 0.0364 0.396
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Brugia malayi Delta serrate ligand family protein 0.0032 0.0096 0.0111
Echinococcus granulosus protein jagged 1 0.0032 0.0096 0.0162
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0002
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0225 0.1058 0.1189
Trypanosoma brucei presenilin-like aspartic peptidase, putative 0.0225 0.1058 0.1189
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0077 0.032 0.3376
Schistosoma mansoni tar DNA-binding protein 0.0045 0.0161 0.0153
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Echinococcus multilocularis protein kinase shaggy 0.0058 0.0225 0.0399
Brugia malayi mbt repeat family protein 0.0044 0.0155 0.0179
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0172 0.0795 0.091
Brugia malayi hypothetical protein 0.011 0.0482 0.0557
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0027 0.0072 0.0064
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Onchocerca volvulus 0.008 0.0336 0.4149
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.001 0.0004
Echinococcus granulosus allatostatin A receptor 0.0015 0.001 0.0004
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.001 0.0004
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.001 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0225 0.1878
Echinococcus multilocularis neurogenic locus protein delta 0.0032 0.0096 0.0162
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.001 0.0004
Schistosoma mansoni hypothetical protein 0.0032 0.0096 0.0088
Echinococcus granulosus enteropeptidase 0.0115 0.0508 0.0922
Brugia malayi hypothetical protein 0.0015 0.001 0.0012
Schistosoma mansoni myelin transcription factor 1 myt1 0.005 0.0185 0.0178
Brugia malayi sulfakinin receptor protein 0.0015 0.001 0.0012
Trypanosoma brucei protein kinase, putative 0.0058 0.0225 0.0223
Echinococcus granulosus potassium voltage gated channel protein 0.0051 0.0189 0.0334
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0072 0.0045
Brugia malayi G-protein coupled receptor 0.0015 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0027 0.0072 0.0074
Echinococcus multilocularis nicalin 0.004 0.0136 0.0236
Onchocerca volvulus 0.0051 0.0189 0.2281
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0015 0.001 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0072 0.1563
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0036 0.0685
Loa Loa (eye worm) MBCTL1 0.005 0.0185 0.0205
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0077 0.032 0.8526
Loa Loa (eye worm) hypothetical protein 0.0037 0.0121 0.0131
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0019 0.0032 0.0045
Schistosoma mansoni myosin xvIII 0.0015 0.001 0.0002
Echinococcus multilocularis geminin 0.0227 0.1071 0.1958
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.002 0.0033 0.0029
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.001 0.0004
Brugia malayi Calcium binding EGF domain containing protein 0.0032 0.0096 0.0111
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Toxoplasma gondii PAN domain-containing protein 0.0899 0.4428 1
Echinococcus granulosus slit 2 protein 0.0032 0.0096 0.0162
Loa Loa (eye worm) hypothetical protein 0.0085 0.0362 0.0409
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.001 0.0002
Schistosoma mansoni cathepsin D (A01 family) 0.0057 0.0222 0.0214
Brugia malayi hypothetical protein 0.0015 0.001 0.0012
Loa Loa (eye worm) MH2 domain-containing protein 0.0085 0.0361 0.0409
Echinococcus granulosus neuropeptide receptor A26 0.0015 0.001 0.0004
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0058 0.0225 0.0223
Brugia malayi Cadherin domain containing protein 0.0032 0.0096 0.0111
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.001 0.0002
Onchocerca volvulus 0.0018 0.0025 0.0188
Brugia malayi glutathione reductase 0.0034 0.0104 0.012
Trypanosoma brucei PAB1-binding protein , putative 0.002 0.0036 0.0004
Echinococcus granulosus neurogenic locus protein delta 0.0032 0.0096 0.0162
Mycobacterium tuberculosis Probable reductase 0.0077 0.032 0.3376
Loa Loa (eye worm) beta-lactamase 0.0027 0.0072 0.0074
Brugia malayi Dopamine receptor protein 1 0.0015 0.001 0.0012
Schistosoma mansoni neuropeptide receptor 0.0015 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Onchocerca volvulus 0.008 0.0336 0.4149
Brugia malayi Cadherin domain containing protein 0.0032 0.0096 0.0111
Echinococcus multilocularis tissue type plasminogen activator 0.0096 0.0415 0.075
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0015 0.001 0.0012
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0034 0.0104 0.0438
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.001 0.0004
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0019 0.0032 0.0028
Onchocerca volvulus 0.0032 0.0096 0.1089
Echinococcus multilocularis GTP binding nuclear protein Ran 0.002 0.0033 0.0046
Schistosoma mansoni importin beta-1 0.0027 0.0068 0.006
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0027 0.0072 0.0074
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0065 0.0261 0.0293
Schistosoma mansoni amine GPCR 0.0015 0.001 0.0002
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.001 0.0004
Plasmodium falciparum plasmepsin I 0.0019 0.0032 0.0597
Loa Loa (eye worm) transcription factor SMAD2 0.0085 0.0361 0.0409
Brugia malayi hypothetical protein 0.0079 0.0328 0.0379
Loa Loa (eye worm) presenilin spe-4 0.0079 0.0328 0.037
Loa Loa (eye worm) hypothetical protein 0.0402 0.1946 0.2242
Schistosoma mansoni hypothetical protein 0.0051 0.0189 0.0181
Trypanosoma cruzi Nicastrin, putative 0.004 0.0136 0.012
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0058 0.0225 0.0217
Schistosoma mansoni tar DNA-binding protein 0.0045 0.0161 0.0153
Echinococcus multilocularis musashi 0.002 0.0037 0.0054
Echinococcus multilocularis fat cadherin tumor suppressor 0.0032 0.0096 0.0162
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Schistosoma mansoni subfamily A22A unassigned peptidase (A22 family) 0.0225 0.1058 0.1051
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Echinococcus granulosus intermediate filament protein 0.002 0.0037 0.0054
Schistosoma mansoni microtubule-associated protein tau 0.0637 0.3119 0.3113
Echinococcus multilocularis neural cadherin 0.0032 0.0096 0.0162
Echinococcus granulosus neurogenic locus notch protein 0.0032 0.0096 0.0162
Toxoplasma gondii ABC1 family protein 0.0027 0.0072 0.0144
Echinococcus multilocularis serotonin receptor 0.0015 0.001 0.0004
Echinococcus multilocularis notch 0.0032 0.0096 0.0162
Echinococcus granulosus serotonin receptor 0.0015 0.001 0.0004
Schistosoma mansoni cellular tumor antigen P53 0.0046 0.0163 0.0155
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Loa Loa (eye worm) hypothetical protein 0.008 0.0337 0.038
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.001 0.0004
Onchocerca volvulus 0.0046 0.0163 0.1946
Entamoeba histolytica hypothetical protein 0.0059 0.0229 0.1917
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1744 0.8654 1
Plasmodium vivax transcription initiation factor IIA subunit 1, putative 0.0052 0.0197 0.4647
Echinococcus granulosus neuropeptide s receptor 0.0015 0.001 0.0004
Onchocerca volvulus 0.002 0.0037 0.0343
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0214 0.0207
Onchocerca volvulus 0.0051 0.0189 0.2281
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0032
Schistosoma mansoni cercarial elastase (S01 family) 0.0051 0.0189 0.0181
Schistosoma mansoni hypothetical protein 0.0032 0.0096 0.0088
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.001 0.0003
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.001 0.0004
Onchocerca volvulus 0.008 0.0336 0.4149
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.001 0.0002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0031 0.0091 0.0096
Brugia malayi RE15519p 0.0015 0.001 0.0012
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0049 0.0178 0.0313
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.001 0.0004
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0059 0.0229 0.0408
Plasmodium falciparum plasmepsin VI 0.0019 0.0032 0.0597
Onchocerca volvulus Arrow homolog 0.008 0.0337 0.416
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0051 0.0189 0.0334
Echinococcus multilocularis polycomb protein SCMH1 0.0044 0.0155 0.027
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.001 0.0002
Trypanosoma brucei importin beta-1 subunit, putative 0.0027 0.0068 0.0041
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0065 0.0261 0.0254
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.001 0.0004
Onchocerca volvulus 0.008 0.0336 0.4149
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Schistosoma mansoni cercarial elastase (S01 family) 0.0051 0.0189 0.0181
Schistosoma mansoni hypothetical protein 0.0032 0.0096 0.0088
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0032 0.0096 0.0088
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.001 0.0004
Leishmania major hypothetical protein, conserved 0.0027 0.0072 0.0045
Loa Loa (eye worm) Notch2 0.0032 0.0096 0.0102
Echinococcus granulosus laminin 0.008 0.0337 0.0605
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.001 0.0004
Echinococcus granulosus gamma secretase subunit aph 1 0.1101 0.5439 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.002 0.0033 0.0608
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0366 0.1765 0.1758
Brugia malayi Fibulin-1 precursor 0.008 0.0337 0.0389
Schistosoma mansoni neuropeptide receptor 0.0015 0.001 0.0002
Toxoplasma gondii PAN domain-containing protein 0.008 0.0336 0.0742
Schistosoma mansoni voltage-gated potassium channel 0.0051 0.0189 0.0181
Echinococcus granulosus delta-like protein 1 0.0032 0.0096 0.0162
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.001 0.0002
Trypanosoma brucei importin beta-1 subunit, putative 0.0027 0.0068 0.0041
Brugia malayi beta-lactamase family protein 0.0027 0.0072 0.0083
Brugia malayi neuropeptide F receptor 0.0015 0.001 0.0012
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.001 0.0004
Brugia malayi ORL1-like opioid receptor 0.0015 0.001 0.0012
Schistosoma mansoni cercarial elastase (S01 family) 0.0051 0.0189 0.0181
Schistosoma mansoni ran 0.002 0.0033 0.0025
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0172 0.0795 0.0788
Toxoplasma gondii calcium binding egf domain-containing protein 0.008 0.0337 0.0744
Loa Loa (eye worm) hypothetical protein 0.008 0.0336 0.0379
Echinococcus granulosus lamin dm0 0.002 0.0037 0.0054
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1744 0.8654 1
Schistosoma mansoni hypothetical protein 0.0032 0.0096 0.0088
Brugia malayi putative neuropeptide receptor 0.0015 0.001 0.0012
Echinococcus granulosus beta LACTamase domain containing family member 0.0027 0.0072 0.0117
Onchocerca volvulus 0.0044 0.0155 0.1842
Onchocerca volvulus 0.0058 0.0225 0.2735
Onchocerca volvulus 0.0018 0.0025 0.0188
Echinococcus multilocularis protein jagged 2 0.0032 0.0096 0.0162
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.001 0.0004
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Echinococcus multilocularis histone acetyltransferase MYST2 0.005 0.0185 0.0327
Brugia malayi hypothetical protein 0.0015 0.001 0.0012
Trypanosoma brucei trypanothione reductase 0.0034 0.0104 0.0083
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0065 0.0261 0.0467
Plasmodium falciparum glycogen synthase kinase 3 0.0058 0.0225 0.5329
Echinococcus multilocularis sex peptide receptor 0.0015 0.001 0.0004
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.001 0.0003
Brugia malayi PAN domain containing protein 0.008 0.0336 0.0388
Schistosoma mansoni cercarial elastase (S01 family) 0.0051 0.0189 0.0181
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.001 0.0002
Schistosoma mansoni gamma-secretase subunit aph-1 0.1101 0.5439 0.5435
Loa Loa (eye worm) hypothetical protein 0.0027 0.0068 0.0069
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0032 0.0096 0.0111
Entamoeba histolytica hypothetical protein 0.004 0.0136 0.1007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0019 0.0032 0.0055
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0045 0.0161 0.0153
Loa Loa (eye worm) hypothetical protein 0.0021 0.0041 0.0039
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.001 0.0004
Echinococcus granulosus g protein coupled receptor 0.0015 0.001 0.0004
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Echinococcus multilocularis laminin 0.008 0.0337 0.0605
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Schistosoma mansoni biogenic amine receptor 0.0015 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0072 0.0074
Echinococcus granulosus presenilin enhancer 2 0.0211 0.0989 0.1807
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0051 0.0189 0.0181
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Giardia lamblia High cysteine protein 0.0032 0.0096 0.3281
Trypanosoma cruzi Nicastrin, putative 0.004 0.0136 0.012
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0032 0.0096 0.0102
Echinococcus granulosus importin subunit beta 1 0.0027 0.0068 0.011
Echinococcus multilocularis orexin receptor type 2 0.0015 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0096 0.0415 0.0471
Loa Loa (eye worm) hypothetical protein 0.008 0.0336 0.0379
Toxoplasma gondii PAN domain-containing protein 0.0899 0.4428 1
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.001 0.0002
Echinococcus multilocularis tfiia large subunit 0.0139 0.063 0.1145
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.001 0.0004
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.008 0.0337 0.038
Echinococcus multilocularis presenilin enhancer 2 0.0211 0.0989 0.1807
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.001 0.0004
Onchocerca volvulus 0.0027 0.0072 0.0781
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0216 0.1015 0.1165
Toxoplasma gondii aspartyl protease ASP1 0.0019 0.0032 0.0055
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0225 0.1058 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Schistosoma mansoni hypothetical protein 0.0018 0.0025 0.0017
Brugia malayi mbt repeat family protein 0.0044 0.0155 0.0179
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.001 0.0002
Loa Loa (eye worm) trypsin family protein 0.0051 0.0189 0.021
Echinococcus granulosus SAM and MBT domain containing protein 0.0044 0.0155 0.027
Plasmodium falciparum importin beta, putative 0.0027 0.0068 0.147
Schistosoma mansoni notch 0.0032 0.0096 0.0088
Trichomonas vaginalis esterase, putative 0.0027 0.0072 0.0383
Echinococcus multilocularis enteropeptidase 0.0115 0.0508 0.0922
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.001 0.0004
Echinococcus granulosus GTP binding nuclear protein Ran 0.002 0.0033 0.0046
Brugia malayi Thioredoxin reductase 0.0034 0.0104 0.012
Onchocerca volvulus 0.0096 0.0415 0.5158
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.001 0.0002
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.001 0.0003
Echinococcus multilocularis importin subunit beta 1 0.0027 0.0068 0.011
Trichomonas vaginalis D-aminoacylase, putative 0.0027 0.0072 0.0383
Schistosoma mansoni voltage-gated potassium channel 0.0051 0.0189 0.0181
Loa Loa (eye worm) hypothetical protein 0.0891 0.4391 0.507
Schistosoma mansoni hypothetical protein 0.0021 0.0041 0.0034
Echinococcus granulosus g-protein coupled receptor 0.0015 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0072 0.0074
Schistosoma mansoni amine GPCR 0.0015 0.001 0.0002
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.001 0.0004
Leishmania major trypanothione reductase 0.0034 0.0104 0.0083
Giardia lamblia Kinase, CMGC GSK 0.0058 0.0225 1
Brugia malayi EGF-like domain containing protein 0.0032 0.0096 0.0111
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0032 0.0096 0.1089
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0032
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.003 0.0084 0.0076
Schistosoma mansoni tar DNA-binding protein 0.0045 0.0161 0.0153
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.001 0.0003
Mycobacterium tuberculosis Probable dehydrogenase 0.0077 0.032 0.3376
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0051 0.0189 0.0334
Onchocerca volvulus 0.0051 0.0189 0.2281
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.001 0.0002
Brugia malayi ATP synthase epsilon chain, mitochondrial 0.0015 0.0008 0.0009
Schistosoma mansoni hypothetical protein 0.0284 0.1355 0.1348
Echinococcus granulosus protein jagged 1 0.0032 0.0096 0.0162
Brugia malayi intermediate filament protein 0.002 0.0037 0.0043
Brugia malayi Melatonin receptor type 1A 0.0015 0.001 0.0012
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0086 0.0364 0.396
Trichomonas vaginalis Nicastrin precursor, putative 0.011 0.0482 0.4387
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.001 0.0004
Echinococcus granulosus microtubule associated protein 2 0.0637 0.3119 0.5728
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0051 0.0189 0.0334
Loa Loa (eye worm) TAR-binding protein 0.0045 0.0161 0.0177
Brugia malayi hypothetical protein 0.0059 0.0229 0.0265
Trypanosoma brucei Nicastrin, putative 0.004 0.0136 0.012
Trichomonas vaginalis penicillin-binding protein, putative 0.0027 0.0072 0.0383
Brugia malayi Presenilin spe-4 0.0079 0.0328 0.0379
Schistosoma mansoni cercarial elastase (S01 family) 0.0051 0.0189 0.0181
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Schistosoma mansoni notch 0.0032 0.0096 0.0088
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0096 0.0415 1
Onchocerca volvulus 0.0032 0.0096 0.1089
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0225 0.1058 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.001 0.0002
Schistosoma mansoni adenoreceptor 0.0015 0.001 0.0002
Echinococcus granulosus neural cadherin 0.0032 0.0096 0.0162
Loa Loa (eye worm) glutathione reductase 0.0034 0.0104 0.0111
Toxoplasma gondii calcium binding egf domain-containing protein 0.008 0.0337 0.0744
Entamoeba histolytica presenilin 1 peptidase, putative 0.0225 0.1058 1
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.0225 0.1874
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0019 0.0032 0.0045
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0032 0.0024
Trichomonas vaginalis ran, putative 0.002 0.0033 0.0004
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0002
Loa Loa (eye worm) PAN domain-containing protein 0.008 0.0336 0.0379
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0058 0.0225 0.0251
Toxoplasma gondii PAN domain-containing protein 0.008 0.0336 0.0742
Brugia malayi Trypsin family protein 0.0172 0.0795 0.0919
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0036 0.0004
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Schistosoma mansoni laminin gamma-3 chain 0.0032 0.0096 0.0088
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0058 0.0225 0.0491
Loa Loa (eye worm) hypothetical protein 0.008 0.0337 0.038
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.001 0.0003
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0058 0.0225 0.0251
Brugia malayi PAN domain containing protein 0.008 0.0336 0.0388
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0051 0.0189 0.0219
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0027 0.0072 0.0064
Echinococcus granulosus transmembrane protease serine 3 0.0051 0.0189 0.0334
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0051 0.0189 0.0219
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.001 0.0004
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0027 0.0072 0.0083
Brugia malayi GnHR receptor homolog 0.0015 0.001 0.0012
Schistosoma mansoni tfiia large subunit 0.0139 0.063 0.0622
Echinococcus granulosus polycomb protein SCMH1 0.0044 0.0155 0.027
Brugia malayi EGF-like domain containing protein 0.0032 0.0096 0.0111
Schistosoma mansoni lamin 0.002 0.0037 0.0029
Toxoplasma gondii hypothetical protein 0.0079 0.0328 0.0724
Loa Loa (eye worm) hypothetical protein 0.0051 0.0189 0.021
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.005 0.0185 0.0327
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.001 0.0004
Echinococcus granulosus protein jagged 2 0.0032 0.0096 0.0162
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.001 0.0004
Echinococcus granulosus glycoprotein Antigen 5 0.0115 0.0508 0.0922
Brugia malayi EGF-like domain containing protein 0.0032 0.0096 0.0111
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.1744 0.8654 1
Echinococcus multilocularis Nicastrin 0.011 0.0482 0.0873
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0176 0.0815 0.1486
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0015 0.001 0.0012
Mycobacterium tuberculosis Probable oxidoreductase 0.0086 0.0364 0.396
Onchocerca volvulus 0.0121 0.0541 0.6757
Echinococcus multilocularis lamin dm0 0.002 0.0037 0.0054
Onchocerca volvulus 0.0051 0.0189 0.2281
Toxoplasma gondii microneme protein, putative 0.008 0.0336 0.0742
Schistosoma mansoni amine GPCR 0.0015 0.001 0.0002
Schistosoma mansoni cercarial elastase (S01 family) 0.0051 0.0189 0.0181
Giardia lamblia Kinase, CMGC GSK 0.0058 0.0225 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0072 0.0074
Echinococcus granulosus histone acetyltransferase MYST2 0.005 0.0185 0.0327
Echinococcus multilocularis neurogenic locus notch protein 0.0032 0.0096 0.0162
Echinococcus granulosus neurogenic locus notch protein 4 0.0032 0.0096 0.0162
Loa Loa (eye worm) mbt repeat family protein 0.0044 0.0155 0.017
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.001 0.0004
Brugia malayi Muscle positioning protein 4 0.005 0.0186 0.0215
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Echinococcus multilocularis Mastin 0.0115 0.0508 0.0922
Brugia malayi hypothetical protein 0.0051 0.0189 0.0219
Schistosoma mansoni biogenic amine receptor 0.0015 0.001 0.0002
Brugia malayi PAN domain containing protein 0.008 0.0336 0.0388
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0036 0.0685
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0044 0.0155 0.0147
Loa Loa (eye worm) PAN domain-containing protein 0.008 0.0336 0.0379
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Brugia malayi MH2 domain containing protein 0.0085 0.0361 0.0417
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.001 0.0004
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0036 0.0004
Echinococcus granulosus protein jagged 2 0.0032 0.0096 0.0162
Loa Loa (eye worm) hypothetical protein 0.008 0.0336 0.0379
Brugia malayi beta-lactamase 0.0027 0.0072 0.0083
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0015 0.001 0.0012
Brugia malayi PAN domain containing protein 0.008 0.0336 0.0388
Echinococcus granulosus protein kinase shaggy 0.0058 0.0225 0.0399
Brugia malayi EGF-like domain containing protein 0.0032 0.0096 0.0111
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.001 0.0004
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0616 0.3016 0.5538
Brugia malayi latrophilin 2 splice variant baaae 0.0021 0.0041 0.0048
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.001 0.0004
Schistosoma mansoni hypothetical protein 0.0059 0.0229 0.0222
Onchocerca volvulus 0.008 0.0336 0.4149
Trypanosoma cruzi Aph-1 protein, putative 0.0429 0.208 0.2374
Brugia malayi EGF-like domain containing protein 0.0032 0.0096 0.0111
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Echinococcus multilocularis glycoprotein Antigen 5 0.0115 0.0508 0.0922
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0003
Brugia malayi Presenilin family protein 0.0225 0.1058 0.1223
Echinococcus multilocularis snurportin 1 0.0284 0.1355 0.248
Trypanosoma cruzi hypothetical protein, conserved 0.0096 0.0415 0.0443

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 67 % Inhibition of human GSK3beta assessed as remaining enzyme activity at 10 uM ChEMBL. 18006321
Activity (binding) = 67 % Inhibition of human GSK3beta assessed as remaining enzyme activity at 10 uM ChEMBL. 18006321
IC50 (binding) > 10 uM Inhibition of human GSK3beta ChEMBL. 18006321
IC50 (binding) > 10 uM Inhibition of human GSK3beta ChEMBL. 18006321

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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