Detailed information for compound 546605

Basic information

Technical information
  • TDR Targets ID: 546605
  • Name: sodium sulfinomethanolate
  • MW: 118.087 | Formula: CH3NaO3S
  • H donors: 1 H acceptors: 2 LogP: -0.67 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OS(=O)CO[Na]
  • InChi: 1S/CH3O3S.Na/c2-1-5(3)4;/h1H2,(H,3,4);/q-1;+1
  • InChiKey: RUIZPRBDLBRKCT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • D05861
  • Sodium formaldehyde sulfoxylate (NF)
  • Sodium formaldehyde sulfoxylate anhydorous

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0062 0.0383 0.0342
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.038 0.1263
Schistosoma mansoni hypothetical protein 0.007 0.0445 0.0416
Loa Loa (eye worm) jmjC domain-containing protein 0.005 0.0294 0.038
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.007 0.044 0.6843
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0097 0.0151
Mycobacterium leprae Probable two component sensor kinase MprB 0.005 0.0288 0.3689
Schistosoma mansoni microtubule-associated protein tau 0.1352 1 1
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.005 0.0288 0.4125
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.0551 0.0511
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0616 1
Echinococcus granulosus lysine specific demethylase 5A 0.0091 0.0599 0.056
Trypanosoma brucei heat shock protein 90, putative 0.005 0.0288 0.0397
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.0629 0.059
Mycobacterium tuberculosis Possible two component sensor kinase 0.005 0.0288 0.4125
Schistosoma mansoni hypothetical protein 0.0039 0.0213 0.0184
Onchocerca volvulus 0.0085 0.0551 0.2946
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.005 0.0288 0.4125
Echinococcus granulosus jumonji domain containing protein 0.0034 0.0172 0.013
Schistosoma mansoni hypothetical protein 0.0055 0.0329 0.03
Brugia malayi jmjC domain containing protein 0.014 0.0961 0.1464
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0178 0.0137
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0616 0.0899
Trypanosoma brucei Heat shock protein 83, putative 0.005 0.0288 0.0397
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0082 0.004
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0311 0.2241 0.3386
Schistosoma mansoni transcription factor LCR-F1 0.007 0.0445 0.0416
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0045 0.0257 0.0216
Brugia malayi jmjC domain containing protein 0.0024 0.0097 0.0147
Trypanosoma cruzi heat shock protein 90, putative 0.005 0.0288 0.0397
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0027 0.0124 0.1178
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0027 0.0124 0.0145
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0224 0.0183
Echinococcus granulosus lysine specific demethylase 6a 0.0024 0.0097 0.0055
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0663 0.3855
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.038 0.5771
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.014 0.0961 0.0922
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0097 0.0077
Echinococcus multilocularis geminin 0.0168 0.1172 0.1134
Mycobacterium ulcerans putative regultory protein 0.005 0.0288 0.4125
Echinococcus granulosus PHD finger protein rhinoceros 0.0024 0.0101 0.0059
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0785 0.577 0.5752
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.005 0.0288 0.1467
Onchocerca volvulus 0.0027 0.0124 0.0152
Echinococcus multilocularis jumonji domain containing 1A 0.0024 0.0097 0.0055
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0124 0.1178
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0124 0.0189
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.0629 0.059
Echinococcus multilocularis lysine specific demethylase 5A 0.0089 0.0586 0.0546
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0124 0.1178
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0062 0.0383 0.0342
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.005 0.0288 0.6029
Loa Loa (eye worm) hypothetical protein 0.014 0.096 0.1402
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.038 0.0537
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.005 0.0288 0.4125
Onchocerca volvulus 0.0027 0.0124 0.0152
Treponema pallidum chemotaxis histidine kinase (cheA) 0.005 0.0288 1
Loa Loa (eye worm) oxidoreductase 0.0027 0.0124 0.0119
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0097 0.0077
Trypanosoma cruzi DNA topoisomerase II, putative 0.005 0.0288 0.0397
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0068 0.0033
Giardia lamblia Kinase, CMGC MAPK 0.01 0.0663 1
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.007 0.044 1
Entamoeba histolytica hypothetical protein 0.007 0.0445 0.6765
Schistosoma mansoni protein phosphatase 2C 0.0024 0.0097 0.0068
Schistosoma mansoni pyruvate dehydrogenase 0.089 0.656 0.655
Plasmodium falciparum DNA gyrase subunit B 0.005 0.0288 0.6029
Echinococcus multilocularis microtubule associated protein 2 0.1352 1 1
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.005 0.0288 0.4125
Brugia malayi MAP kinase sur-1 0.01 0.0663 0.1011
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.005 0.0288 0.4125
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0026 0.011 0.0069
Brugia malayi heat shock protein 90 0.005 0.0288 0.044
Onchocerca volvulus DNA topoisomerase 2 homolog 0.005 0.0288 0.123
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.089 0.656 0.6546
Giardia lamblia PHD finger protein 15 0.0024 0.0101 0.0703
Echinococcus multilocularis protein patched 0.0041 0.0224 0.0183
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0101 0.1114
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.01 0.0663 0.0971
Schistosoma mansoni survival motor neuron protein 0.0055 0.0329 0.03
Giardia lamblia Heat shock protein HSP 90-alpha 0.005 0.0288 0.3806
Loa Loa (eye worm) hypothetical protein 0.0048 0.0276 0.0352
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.005 0.0288 0.1467
Schistosoma mansoni hypothetical protein 0.0168 0.1172 0.1146
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0616 0.0899
Schistosoma mansoni bromodomain containing protein 0.0061 0.0376 0.0347
Brugia malayi hypothetical protein 0.014 0.096 0.1463
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.038 0.5771
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0027 0.0124 0.0145
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0027 0.0124 0.1178
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0094 0.0616 1
Trypanosoma cruzi DNA topoisomerase II, putative 0.005 0.0288 0.0397
Brugia malayi Bromodomain containing protein 0.0037 0.0195 0.0298
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0083
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0062 0.0383 0.0342
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.005 0.0288 0.0903
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0027 0.0124 0.0082
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0026 0.011 0.0069
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0058 0.0018
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.005 0.0288 1
Trypanosoma cruzi Heat shock protein 83, putative 0.005 0.0288 0.0397
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0097 0.0692
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0027 0.0124 0.0145
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.0629 0.0959
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.005 0.0288 0.1467
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0024 0.0097 0.0103
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.005 0.0288 0.4125
Schistosoma mansoni phosphatidylserine receptor 0.0024 0.0097 0.0068
Plasmodium vivax JmjC domain containing protein 0.0024 0.0097 0.1014
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.005 0.0288 0.0397
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.005 0.0288 0.0247
Schistosoma mansoni endoplasmin 0.005 0.0288 0.026
Brugia malayi Bromodomain containing protein 0.0073 0.046 0.0701
Brugia malayi latrophilin 2 splice variant baaae 0.0134 0.0922 0.1405
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0178 0.0137
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0097 0.0692
Trichomonas vaginalis set domain proteins, putative 0.0229 0.1628 1
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Trichomonas vaginalis endoplasmin, putative 0.005 0.0288 0.1467
Echinococcus multilocularis JmjC domain containing protein 4 0.0024 0.0097 0.0055
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0094 0.0616 1
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0027 0.0124 0.1178
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.014 0.0961 0.0922
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0024 0.0097 0.0068
Echinococcus multilocularis mitogen activated protein kinase 3 0.01 0.0663 0.0624
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0094 0.0616 1
Echinococcus multilocularis expressed conserved protein 0.0089 0.0586 0.0547
Loa Loa (eye worm) hypothetical protein 0.0058 0.0349 0.0465
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0361 0.261 1
Leishmania major acetyl-CoA synthetase, putative 0.0027 0.0124 0.0145
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.038 0.0352
Plasmodium vivax DNA gyrase subunit B, putative 0.005 0.0288 0.6029
Brugia malayi Endoplasmin precursor 0.005 0.0288 0.044
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.035 0.0309
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0134 0.0299
Echinococcus granulosus JmjC domain containing protein 4 0.0024 0.0097 0.0055
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.038 0.5771
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0134 0.0105
Echinococcus granulosus mitogen activated protein kinase 3 0.01 0.0663 0.0624
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0329 0.0501
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0027 0.0124 0.0522
Onchocerca volvulus Huntingtin homolog 0.014 0.096 0.5625
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.005 0.0288 0.1467
Schistosoma mansoni jumonji domain containing protein 0.0024 0.0097 0.0068
Trypanosoma cruzi heat shock protein 90, putative 0.005 0.0288 0.0397
Mycobacterium tuberculosis Conserved protein 0.005 0.0288 0.4125
Echinococcus granulosus geminin 0.0168 0.1172 0.1134
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0197 0.1386 0.2112
Onchocerca volvulus 0.0055 0.0329 0.1494
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0224 0.0183
Loa Loa (eye worm) hypothetical protein 0.007 0.044 0.0604
Plasmodium vivax heat shock protein 86, putative 0.005 0.0288 0.6029
Echinococcus granulosus phd:f box containing protein 0.0024 0.0097 0.0055
Plasmodium vivax DNA topoisomerase II, putative 0.005 0.0288 0.6029
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0027 0.0124 0.0119
Onchocerca volvulus 0.0029 0.0134 0.0221
Loa Loa (eye worm) jmjC domain-containing protein 0.0091 0.0599 0.0849
Brugia malayi jmjC domain containing protein 0.0091 0.0599 0.0914
Echinococcus multilocularis heat shock protein 0.005 0.0288 0.0247
Brugia malayi Probable DNA topoisomerase II 0.005 0.0288 0.044
Plasmodium falciparum DNA topoisomerase 2 0.005 0.0288 0.6029
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0027 0.0124 0.0082
Leishmania major acetyl-CoA synthetase, putative 0.0027 0.0124 0.0145
Trichomonas vaginalis DNA topoisomerase II, putative 0.005 0.0288 0.1467
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.0934 0.0896
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.005 0.0288 0.4125
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0027 0.0124 0.0145
Echinococcus multilocularis phd:f box containing protein 0.0024 0.0097 0.0055
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0027 0.0124 0.0145
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0412 0.6333
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0024 0.0097 0.0103
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0027 0.0124 0.1178
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0027 0.0124 0.1178
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0062 0.0383 0.0584
Leishmania major hypothetical protein, conserved 0.0024 0.0097 0.0103
Mycobacterium ulcerans acetyl-CoA synthetase 0.0027 0.0124 0.1178
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0124 0.0189
Mycobacterium leprae Probable two-component sensor kinase 0.005 0.0288 0.3689
Plasmodium falciparum endoplasmin, putative 0.005 0.0288 0.6029
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0311 0.2241 0.3386
Echinococcus multilocularis survival motor neuron protein 1 0.0269 0.1928 0.1894
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Toxoplasma gondii heat shock protein 90, putative 0.005 0.0288 0.0903
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.005 0.0288 0.4125
Leishmania major developmentally regulated phosphoprotein-like protein 0.089 0.656 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.01 0.0663 0.0971
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.005 0.0288 0.0397
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0616 0.094
Trichomonas vaginalis receptor histidine kinase, putative 0.005 0.0288 0.1467
Loa Loa (eye worm) hypothetical protein 0.0062 0.0383 0.0517
Schistosoma mansoni pyruvate dehydrogenase 0.0841 0.6191 0.618
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0257 0.0229
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0616 0.0899
Trypanosoma brucei heat shock protein 90, putative 0.005 0.0288 0.0397
Echinococcus granulosus peregrin 0.0027 0.0118 0.0076
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0042 0.0013
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.005 0.0288 0.123
Loa Loa (eye worm) hypothetical protein 0.0094 0.0616 0.0875
Echinococcus granulosus DNA topoisomerase 2 alpha 0.005 0.0288 0.0247
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.038 0.034
Brugia malayi jmjC domain containing protein 0.0024 0.0097 0.0147
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.089 0.656 0.6546
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0027 0.0124 0.0258
Echinococcus multilocularis PHD finger protein rhinoceros 0.0024 0.0101 0.0059
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.005 0.0288 0.4125
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0134 0.0105
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Loa Loa (eye worm) heat shock protein 90 0.005 0.0288 0.0371
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0126 0.0085
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.005 0.0288 0.0397
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0062 0.0383 0.0342
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0058 0.0044
Mycobacterium tuberculosis Two component sensor kinase MprB 0.005 0.0288 0.4125
Schistosoma mansoni hypothetical protein 0.0024 0.0101 0.0071
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.0629 1
Echinococcus multilocularis peregrin 0.0027 0.0118 0.0076
Loa Loa (eye worm) hypothetical protein 0.0269 0.1928 0.2888
Schistosoma mansoni pyruvate dehydrogenase 0.0841 0.6191 0.618
Leishmania major hypothetical protein, conserved 0.005 0.0288 0.0397
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Entamoeba histolytica hypothetical protein 0.007 0.0445 0.6765
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Onchocerca volvulus 0.0027 0.0124 0.0152
Echinococcus multilocularis GPCR, family 2 0.0062 0.0383 0.0342
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.005 0.0288 0.3689
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.038 0.0352
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0024 0.0097 0.0152
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.0551 0.0839
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.038 0.5771
Onchocerca volvulus Huntingtin homolog 0.014 0.096 0.5625
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0077
Trypanosoma cruzi heat shock protein 85, putative 0.005 0.0288 0.0397
Brugia malayi DNA topoisomerase II, alpha isozyme 0.005 0.0288 0.044
Entamoeba histolytica hypothetical protein 0.007 0.0445 0.6765
Schistosoma mansoni hypothetical protein 0.0062 0.0383 0.0355
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0311 0.2241 0.3386
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.005 0.0288 1
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0027 0.0124 0.1178
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0616 0.094
Entamoeba histolytica acyl-CoA synthetase, putative 0.0094 0.0616 0.9775
Trypanosoma cruzi heat shock protein 85, putative 0.005 0.0288 0.0397
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Toxoplasma gondii DNA topoisomerase 2, putative 0.005 0.0288 0.0903
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0197 0.1386 0.2056
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.0551 0.0511
Schistosoma mansoni hypothetical protein 0.0062 0.0383 0.0355
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.005 0.0288 0.4125
Loa Loa (eye worm) hypothetical protein 0.005 0.0292 0.0378
Echinococcus granulosus histone lysine methyltransferase setb 0.0045 0.0257 0.0216
Trichomonas vaginalis receptor histidine kinase, putative 0.005 0.0288 0.1467
Brugia malayi PHD-finger family protein 0.0024 0.0101 0.0153
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.089 0.656 0.6546
Loa Loa (eye worm) hypothetical protein 0.0027 0.0124 0.0119
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0134 0.0093
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0097 0.0151
Mycobacterium ulcerans two component sensor kinase MprB 0.005 0.0288 0.4125
Echinococcus multilocularis lysine specific demethylase 6a 0.0024 0.0097 0.0055
Entamoeba histolytica acyl-CoA synthetase, putative 0.0094 0.0616 0.9775
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0097 0.0103
Echinococcus granulosus heat shock protein 90 0.005 0.0288 0.0247
Schistosoma mansoni jumonji/arid domain-containing protein 0.0091 0.0599 0.0572
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0027 0.0124 0.1178
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0058 0.0044
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Toxoplasma gondii PHD-finger domain-containing protein 0.0024 0.0101 0.0167
Schistosoma mansoni zinc finger protein 0.0019 0.006 0.0031
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0124 0.0189
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0097 0.0103
Schistosoma mansoni hypothetical protein 0.0168 0.1172 0.1146
Plasmodium falciparum heat shock protein 90 0.005 0.0288 0.6029
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0058 0.0088
Brugia malayi Bromodomain containing protein 0.0027 0.0118 0.0179
Mycobacterium ulcerans hypothetical protein 0.0094 0.0616 1
Giardia lamblia Pms1-like protein 0.005 0.0288 0.3806
Brugia malayi Pre-SET motif family protein 0.0201 0.1421 0.2166
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0027 0.0124 0.1178
Loa Loa (eye worm) hypothetical protein 0.005 0.0288 0.0371
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0094 0.0616 1
Schistosoma mansoni phd/f-box containing protein 0.0024 0.0097 0.0068
Entamoeba histolytica DNA topoisomerase II, putative 0.005 0.0288 0.4033
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.035 0.0309
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0024 0.0101 0.0071
Schistosoma mansoni hypothetical protein 0.0062 0.0383 0.0355
Plasmodium vivax acyl-CoA synthetase, putative 0.007 0.044 1
Echinococcus granulosus GPCR family 2 0.0062 0.0383 0.0342
Schistosoma mansoni DNA topoisomerase II 0.005 0.0288 0.026
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0027 0.0124 0.1178
Brugia malayi jmjC domain containing protein 0.0024 0.0097 0.0147
Entamoeba histolytica heat shock protein 90, putative 0.005 0.0288 0.4033
Loa Loa (eye worm) hypothetical protein 0.0094 0.0616 0.0875
Echinococcus granulosus mitogen activated protein kinase 0.01 0.0663 0.0624
Trichomonas vaginalis heat shock protein, putative 0.005 0.0288 0.1467
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0027 0.0124 0.1178
Plasmodium falciparum JmjC domain-containing protein, putative 0.0024 0.0097 0.1014
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0124 0.1178
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Loa Loa (eye worm) hypothetical protein 0.0027 0.0124 0.0119
Echinococcus granulosus tumor protein p63 0.0327 0.2357 0.2325
Trypanosoma brucei developmentally regulated phosphoprotein 0.089 0.656 1
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Toxoplasma gondii heat shock protein HSP90 0.005 0.0288 0.0903
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0124 0.0189
Trichomonas vaginalis antibiotic synthetase, putative 0.0027 0.0124 0.0419
Toxoplasma gondii PHD-finger domain-containing protein 0.0024 0.0101 0.0167
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0027 0.0124 0.0145
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0027 0.0124 0.1178
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0058 0.0016
Schistosoma mansoni hypothetical protein 0.0134 0.0922 0.0895
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.005 0.0288 0.4125
Onchocerca volvulus 0.0031 0.0152 0.0334
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.01 0.0663 0.0971
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Schistosoma mansoni ap endonuclease 0.0019 0.0058 0.0029
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0082 0.004
Mycobacterium ulcerans DNA gyrase subunit B 0.005 0.0288 0.4125
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.01 0.0663 0.0971
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0616 1
Schistosoma mansoni hypothetical protein 0.0039 0.0213 0.0184
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.005 0.0288 0.4125
Schistosoma mansoni ap endonuclease 0.0019 0.0058 0.0029
Onchocerca volvulus 0.0229 0.1628 1
Echinococcus multilocularis heat shock protein 90 0.005 0.0288 0.0247
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0124 0.0522
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.005 0.0288 0.4125
Echinococcus granulosus heat shock protein 0.005 0.0288 0.0247
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0124 0.1178
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0663 0.0636
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.005 0.0288 0.5582
Loa Loa (eye worm) endoplasmin 0.005 0.0288 0.0371
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0101 0.0083
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0412 0.6333
Plasmodium vivax acetyl-CoA synthetase, putative 0.0027 0.0124 0.1721
Mycobacterium ulcerans two component regulator - sensor kinase 0.005 0.0288 0.4125
Loa Loa (eye worm) hypothetical protein 0.089 0.656 1
Echinococcus multilocularis tumor protein p63 0.0327 0.2357 0.2325
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0663 0.3855
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.01 0.0663 0.0971
Loa Loa (eye worm) hypothetical protein 0.0134 0.0922 0.1344
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0077
Loa Loa (eye worm) TOPoisomerase family member 0.005 0.0288 0.0371
Loa Loa (eye worm) hypothetical protein 0.0197 0.1386 0.2056
Echinococcus granulosus expressed conserved protein 0.0089 0.0586 0.0547
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.01 0.0663 0.0971
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Brugia malayi PHD-finger family protein 0.0024 0.0099 0.015
Entamoeba histolytica hypothetical protein 0.007 0.0445 0.6765
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0027 0.0124 0.0119
Schistosoma mansoni heat shock protein 0.005 0.0288 0.026
Plasmodium falciparum phd finger protein, putative 0.0024 0.0101 0.1114
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0257 0.0229
Plasmodium vivax hypothetical protein, conserved 0.005 0.0288 0.6029
Leishmania major DNA topoisomerase ii 0.005 0.0288 0.0397
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Loa Loa (eye worm) hypothetical protein 0.0045 0.0257 0.0324
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0224 0.0272
Mycobacterium ulcerans fatty-acid-CoA ligase 0.007 0.044 0.6843
Trichomonas vaginalis antibiotic synthetase, putative 0.0027 0.0124 0.0419
Onchocerca volvulus 0.0048 0.0276 0.1147
Brugia malayi jmjC domain containing protein 0.0024 0.0097 0.0147
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.005 0.0288 0.4125
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0027 0.0124 0.1178
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0311 0.2241 0.8552
Brugia malayi hypothetical protein 0.007 0.0445 0.0678
Mycobacterium tuberculosis Probable two component sensor kinase 0.005 0.0288 0.4125
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.005 0.0288 0.4125
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0616 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0124 0.1178
Trypanosoma brucei protein kinase, putative 0.01 0.0663 0.0971
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.005 0.0288 0.0903
Schistosoma mansoni hypothetical protein 0.0039 0.0213 0.0184
Brugia malayi hypothetical protein 0.0269 0.1928 0.2939
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0027 0.0124 0.1178
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0124 0.0189
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0097 0.0077
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Loa Loa (eye worm) hypothetical protein 0.0041 0.0227 0.0277
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0224 0.0183
Echinococcus granulosus survival motor neuron protein 1 0.0269 0.1928 0.1894
Echinococcus granulosus jumonji domain containing 1A 0.0024 0.0097 0.0055
Brugia malayi Latrophilin receptor protein 2 0.0062 0.0383 0.0584
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.0445 0.0404
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0095 0.0668
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.005 0.0288 0.3689
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0097 0.1011
Plasmodium vivax SET domain protein, putative 0.0029 0.0134 0.1998
Schistosoma mansoni hypothetical protein 0.0039 0.0213 0.0184
Trypanosoma cruzi heat shock protein 85, putative 0.005 0.0288 0.0397
Echinococcus granulosus zinc finger protein 0.0019 0.006 0.0018
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0663 0.3855
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0616 0.094
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0097 0.1011
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.01 0.0663 0.2372
Echinococcus multilocularis jumonji domain containing protein 0.0034 0.0172 0.013
Loa Loa (eye worm) hypothetical protein 0.007 0.044 0.0604
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0094 0.0616 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0288 0.0371
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0027 0.0124 0.0258
Mycobacterium tuberculosis Probable sensor protein KdpD 0.005 0.0288 0.4125
Schistosoma mansoni heat shock protein 0.005 0.0288 0.026
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0094 0.0616 1
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0024 0.0097 0.0103
Brugia malayi CHE-14 protein 0.0041 0.0224 0.0341
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0094 0.0616 1
Schistosoma mansoni jumonji domain containing protein 0.0123 0.0838 0.0811
Loa Loa (eye worm) hypothetical protein 0.007 0.044 0.0604
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.005 0.0288 0.0397
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0058 0.0016
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.005 0.0288 0.4125
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0097 0.1677
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.01 0.0663 0.0947
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0027 0.0124 0.0145
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.0445 0.0404
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0412 0.6333
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.005 0.0288 0.1467
Brugia malayi Calcitonin receptor-like protein seb-1 0.0197 0.1386 0.2112
Echinococcus multilocularis protein dispatched 1 0.0047 0.0267 0.0226
Entamoeba histolytica hypothetical protein 0.0024 0.0097 0.0676
Leishmania major mitochondrial DNA topoisomerase II 0.005 0.0288 0.0397
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.0934 0.0896
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0042 0.0013
Schistosoma mansoni jumonji/arid domain-containing protein 0.0091 0.0599 0.0572
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0097 0.1677
Schistosoma mansoni hypothetical protein 0.002 0.0068 0.0039
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Loa Loa (eye worm) hypothetical protein 0.0039 0.0213 0.0256
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Loa Loa (eye worm) hypothetical protein 0.0094 0.0616 0.0875
Onchocerca volvulus 0.0094 0.0616 0.3377
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0027 0.0124 0.1721
Trypanosoma brucei DNA topoisomerase II beta, putative 0.005 0.0288 0.0397
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0224 0.1056
Entamoeba histolytica acyl-coA synthetase, putative 0.0094 0.0616 0.9775
Loa Loa (eye worm) hypothetical protein 0.0085 0.0551 0.0774
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0058 0.0044
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.0551 0.0523
Trichomonas vaginalis sensor histidine kinase, putative 0.005 0.0288 0.1467
Chlamydia trachomatis DNA gyrase subunit B 0.005 0.0288 0.5582
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.064 0.0613
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0027 0.0124 0.1151
Loa Loa (eye worm) hypothetical protein 0.014 0.096 0.1402
Plasmodium falciparum acyl-CoA synthetase 0.007 0.044 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0201 0.1421 0.211
Trypanosoma brucei DNA topoisomerase ii 0.005 0.0288 0.0397
Loa Loa (eye worm) hypothetical protein 0.0041 0.0224 0.0272
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0412 0.6333
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.005 0.0288 0.0397
Onchocerca volvulus DNA topoisomerase 2 homolog 0.005 0.0288 0.123
Echinococcus multilocularis mitogen activated protein kinase 0.01 0.0663 0.0624
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0094 0.0616 1
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0027 0.0124 0.1178
Loa Loa (eye worm) latrophilin receptor protein 2 0.0062 0.0383 0.0517
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.005 0.0288 1
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Loa Loa (eye worm) hypothetical protein 0.007 0.044 0.0604
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0024 0.0097 0.0152
Chlamydia trachomatis DNA gyrase subunit B 0.005 0.0288 0.5582
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.005 0.0288 1
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Schistosoma mansoni patched 1 0.0041 0.0224 0.0195
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Schistosoma mansoni endoplasmin 0.005 0.0288 0.026
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0082 0.0052
Echinococcus multilocularis zinc finger protein 0.0019 0.006 0.0018
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0027 0.0124 0.0189
Trichomonas vaginalis heat shock protein, putative 0.005 0.0288 0.1467
Loa Loa (eye worm) hypothetical protein 0.0095 0.0629 0.0895
Entamoeba histolytica heat shock protein 90, putative 0.005 0.0288 0.4033
Brugia malayi Pre-SET motif family protein 0.0029 0.0134 0.0205
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.005 0.0288 0.044
Plasmodium vivax endoplasmin, putative 0.005 0.0288 0.6029
Toxoplasma gondii propionate-CoA ligase 0.0027 0.0124 0.0258
Schistosoma mansoni hypothetical protein 0.0062 0.0383 0.0355
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0276 0.0247
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0097 0.0692
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0058 0.0044
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.089 0.656 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0196 0.0229
Loa Loa (eye worm) hypothetical protein 0.007 0.044 0.0604
Loa Loa (eye worm) hypothetical protein 0.0068 0.0429 0.0588
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.005 0.0288 0.4125
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0027 0.0124 0.0522
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.01 0.0663 0.0971
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0663 0.3855
Schistosoma mansoni acetyl-CoA synthetase 0.0027 0.0124 0.0095
Brugia malayi kinase, mitochondrial precursor 0.089 0.656 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.038 0.034

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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