Detailed information for compound 572985

Basic information

Technical information
  • TDR Targets ID: 572985
  • Name: sodium sulfinomethanolate dihydrate
  • MW: 154.118 | Formula: CH7NaO5S
  • H donors: 3 H acceptors: 4 LogP: -1.62 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OS(=O)CO[Na].O.O
  • InChi: 1S/CH3O3S.Na.2H2O/c2-1-5(3)4;;;/h1H2,(H,3,4);;2*1H2/q-1;+1;;
  • InChiKey: VJWVWUHJLZEHOU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 6035-47-8
  • 79-25-4
  • Formaldehyde sodium sulfoxylate dihydrate
  • Methanesulfinic acid, hydroxy-, monosodium salt, dihydrate
  • Monosodium hydroxymethanesulfinate dihydrate
  • Sodium Formaldehyde Sulfoxylate [USAN]
  • Sodium formaldehydesulfoxylate dihydrate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0097 0.1011
Trypanosoma cruzi heat shock protein 85, putative 0.005 0.0288 0.0397
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0616 0.094
Echinococcus granulosus zinc finger protein 0.0019 0.006 0.0018
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0663 0.3855
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.01 0.0663 0.2372
Plasmodium vivax SET domain protein, putative 0.0029 0.0134 0.1998
Schistosoma mansoni hypothetical protein 0.0039 0.0213 0.0184
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0097 0.1011
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.005 0.0288 0.3689
Schistosoma mansoni heat shock protein 0.005 0.0288 0.026
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0094 0.0616 1
Mycobacterium tuberculosis Probable sensor protein KdpD 0.005 0.0288 0.4125
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0024 0.0097 0.0103
Brugia malayi CHE-14 protein 0.0041 0.0224 0.0341
Loa Loa (eye worm) hypothetical protein 0.007 0.044 0.0604
Echinococcus multilocularis jumonji domain containing protein 0.0034 0.0172 0.013
Loa Loa (eye worm) hypothetical protein 0.005 0.0288 0.0371
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0027 0.0124 0.0258
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0094 0.0616 1
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.005 0.0288 0.4125
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0097 0.1677
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0027 0.0124 0.0145
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.01 0.0663 0.0947
Loa Loa (eye worm) hypothetical protein 0.007 0.044 0.0604
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0094 0.0616 1
Schistosoma mansoni jumonji domain containing protein 0.0123 0.0838 0.0811
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.005 0.0288 0.0397
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0058 0.0016
Leishmania major mitochondrial DNA topoisomerase II 0.005 0.0288 0.0397
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.0934 0.0896
Brugia malayi Calcitonin receptor-like protein seb-1 0.0197 0.1386 0.2112
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0412 0.6333
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.005 0.0288 0.1467
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.0445 0.0404
Echinococcus multilocularis protein dispatched 1 0.0047 0.0267 0.0226
Entamoeba histolytica hypothetical protein 0.0024 0.0097 0.0676
Trichomonas vaginalis antibiotic synthetase, putative 0.0027 0.0124 0.0419
Onchocerca volvulus 0.0048 0.0276 0.1147
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0224 0.0272
Mycobacterium ulcerans fatty-acid-CoA ligase 0.007 0.044 0.6843
Loa Loa (eye worm) hypothetical protein 0.0045 0.0257 0.0324
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0311 0.2241 0.8552
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.005 0.0288 0.4125
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0027 0.0124 0.1178
Mycobacterium tuberculosis Probable two component sensor kinase 0.005 0.0288 0.4125
Brugia malayi hypothetical protein 0.007 0.0445 0.0678
Brugia malayi jmjC domain containing protein 0.0024 0.0097 0.0147
Schistosoma mansoni hypothetical protein 0.0039 0.0213 0.0184
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.005 0.0288 0.0903
Trypanosoma brucei protein kinase, putative 0.01 0.0663 0.0971
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0124 0.1178
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0027 0.0124 0.1178
Brugia malayi hypothetical protein 0.0269 0.1928 0.2939
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0616 1
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.005 0.0288 0.4125
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.0445 0.0404
Echinococcus granulosus jumonji domain containing 1A 0.0024 0.0097 0.0055
Brugia malayi Latrophilin receptor protein 2 0.0062 0.0383 0.0584
Echinococcus granulosus survival motor neuron protein 1 0.0269 0.1928 0.1894
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0224 0.0183
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0095 0.0668
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0097 0.0077
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0124 0.0189
Loa Loa (eye worm) hypothetical protein 0.0041 0.0227 0.0277
Chlamydia trachomatis DNA gyrase subunit B 0.005 0.0288 0.5582
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0024 0.0097 0.0152
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.005 0.0288 1
Schistosoma mansoni patched 1 0.0041 0.0224 0.0195
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0027 0.0124 0.1178
Loa Loa (eye worm) latrophilin receptor protein 2 0.0062 0.0383 0.0517
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.005 0.0288 1
Loa Loa (eye worm) hypothetical protein 0.007 0.044 0.0604
Echinococcus multilocularis zinc finger protein 0.0019 0.006 0.0018
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0027 0.0124 0.0189
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0082 0.0052
Trichomonas vaginalis heat shock protein, putative 0.005 0.0288 0.1467
Schistosoma mansoni endoplasmin 0.005 0.0288 0.026
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Toxoplasma gondii propionate-CoA ligase 0.0027 0.0124 0.0258
Plasmodium vivax endoplasmin, putative 0.005 0.0288 0.6029
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.005 0.0288 0.044
Brugia malayi Pre-SET motif family protein 0.0029 0.0134 0.0205
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0058 0.0044
Schistosoma mansoni hypothetical protein 0.0062 0.0383 0.0355
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0097 0.0692
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0276 0.0247
Entamoeba histolytica heat shock protein 90, putative 0.005 0.0288 0.4033
Loa Loa (eye worm) hypothetical protein 0.0095 0.0629 0.0895
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0663 0.3855
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.01 0.0663 0.0971
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.005 0.0288 0.4125
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0027 0.0124 0.0522
Brugia malayi kinase, mitochondrial precursor 0.089 0.656 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.038 0.034
Schistosoma mansoni acetyl-CoA synthetase 0.0027 0.0124 0.0095
Loa Loa (eye worm) hypothetical protein 0.0037 0.0196 0.0229
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.089 0.656 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0429 0.0588
Loa Loa (eye worm) hypothetical protein 0.007 0.044 0.0604
Loa Loa (eye worm) hypothetical protein 0.0039 0.0213 0.0256
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0097 0.1677
Schistosoma mansoni jumonji/arid domain-containing protein 0.0091 0.0599 0.0572
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0042 0.0013
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Schistosoma mansoni hypothetical protein 0.002 0.0068 0.0039
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0027 0.0124 0.1721
Trypanosoma brucei DNA topoisomerase II beta, putative 0.005 0.0288 0.0397
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Loa Loa (eye worm) hypothetical protein 0.0094 0.0616 0.0875
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Onchocerca volvulus 0.0094 0.0616 0.3377
Chlamydia trachomatis DNA gyrase subunit B 0.005 0.0288 0.5582
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.064 0.0613
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.0551 0.0523
Trichomonas vaginalis sensor histidine kinase, putative 0.005 0.0288 0.1467
Loa Loa (eye worm) hypothetical protein 0.014 0.096 0.1402
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0027 0.0124 0.1151
Entamoeba histolytica acyl-coA synthetase, putative 0.0094 0.0616 0.9775
Loa Loa (eye worm) hypothetical protein 0.0085 0.0551 0.0774
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0224 0.1056
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0058 0.0044
Onchocerca volvulus DNA topoisomerase 2 homolog 0.005 0.0288 0.123
Echinococcus multilocularis mitogen activated protein kinase 0.01 0.0663 0.0624
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0094 0.0616 1
Plasmodium falciparum acyl-CoA synthetase 0.007 0.044 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0201 0.1421 0.211
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.005 0.0288 0.0397
Loa Loa (eye worm) hypothetical protein 0.0041 0.0224 0.0272
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0412 0.6333
Trypanosoma brucei DNA topoisomerase ii 0.005 0.0288 0.0397
Schistosoma mansoni hypothetical protein 0.0168 0.1172 0.1146
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0097 0.0103
Brugia malayi Bromodomain containing protein 0.0027 0.0118 0.0179
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0058 0.0088
Plasmodium falciparum heat shock protein 90 0.005 0.0288 0.6029
Schistosoma mansoni zinc finger protein 0.0019 0.006 0.0031
Toxoplasma gondii PHD-finger domain-containing protein 0.0024 0.0101 0.0167
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0124 0.0189
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0094 0.0616 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0288 0.0371
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0027 0.0124 0.1178
Giardia lamblia Pms1-like protein 0.005 0.0288 0.3806
Mycobacterium ulcerans hypothetical protein 0.0094 0.0616 1
Brugia malayi Pre-SET motif family protein 0.0201 0.1421 0.2166
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0024 0.0101 0.0071
Schistosoma mansoni hypothetical protein 0.0062 0.0383 0.0355
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.035 0.0309
Echinococcus granulosus GPCR family 2 0.0062 0.0383 0.0342
Plasmodium vivax acyl-CoA synthetase, putative 0.007 0.044 1
Schistosoma mansoni phd/f-box containing protein 0.0024 0.0097 0.0068
Entamoeba histolytica DNA topoisomerase II, putative 0.005 0.0288 0.4033
Trichomonas vaginalis heat shock protein, putative 0.005 0.0288 0.1467
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0027 0.0124 0.1178
Echinococcus granulosus mitogen activated protein kinase 0.01 0.0663 0.0624
Loa Loa (eye worm) hypothetical protein 0.0094 0.0616 0.0875
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0027 0.0124 0.1178
Schistosoma mansoni DNA topoisomerase II 0.005 0.0288 0.026
Entamoeba histolytica heat shock protein 90, putative 0.005 0.0288 0.4033
Brugia malayi jmjC domain containing protein 0.0024 0.0097 0.0147
Brugia malayi DNA topoisomerase II, alpha isozyme 0.005 0.0288 0.044
Entamoeba histolytica acyl-CoA synthetase, putative 0.0094 0.0616 0.9775
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0616 0.094
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0027 0.0124 0.1178
Entamoeba histolytica hypothetical protein 0.007 0.0445 0.6765
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.005 0.0288 1
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0311 0.2241 0.3386
Schistosoma mansoni hypothetical protein 0.0062 0.0383 0.0355
Trypanosoma cruzi heat shock protein 85, putative 0.005 0.0288 0.0397
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.005 0.0288 0.4125
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0197 0.1386 0.2056
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.0551 0.0511
Schistosoma mansoni hypothetical protein 0.0062 0.0383 0.0355
Loa Loa (eye worm) hypothetical protein 0.005 0.0292 0.0378
Toxoplasma gondii DNA topoisomerase 2, putative 0.005 0.0288 0.0903
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Trypanosoma cruzi heat shock protein 85, putative 0.005 0.0288 0.0397
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Loa Loa (eye worm) hypothetical protein 0.0027 0.0124 0.0119
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0097 0.0151
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0134 0.0093
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Brugia malayi PHD-finger family protein 0.0024 0.0101 0.0153
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.089 0.656 0.6546
Trichomonas vaginalis receptor histidine kinase, putative 0.005 0.0288 0.1467
Echinococcus granulosus histone lysine methyltransferase setb 0.0045 0.0257 0.0216
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0058 0.0044
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0027 0.0124 0.1178
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Entamoeba histolytica acyl-CoA synthetase, putative 0.0094 0.0616 0.9775
Echinococcus multilocularis lysine specific demethylase 6a 0.0024 0.0097 0.0055
Mycobacterium ulcerans two component sensor kinase MprB 0.005 0.0288 0.4125
Schistosoma mansoni jumonji/arid domain-containing protein 0.0091 0.0599 0.0572
Echinococcus granulosus heat shock protein 90 0.005 0.0288 0.0247
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0097 0.0103
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0101 0.0083
Loa Loa (eye worm) endoplasmin 0.005 0.0288 0.0371
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.005 0.0288 0.5582
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0412 0.6333
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0124 0.1178
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Echinococcus granulosus heat shock protein 0.005 0.0288 0.0247
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0663 0.0636
Loa Loa (eye worm) hypothetical protein 0.089 0.656 1
Echinococcus multilocularis tumor protein p63 0.0327 0.2357 0.2325
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0077
Loa Loa (eye worm) hypothetical protein 0.0134 0.0922 0.1344
Loa Loa (eye worm) TOPoisomerase family member 0.005 0.0288 0.0371
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.01 0.0663 0.0971
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0663 0.3855
Mycobacterium ulcerans two component regulator - sensor kinase 0.005 0.0288 0.4125
Plasmodium vivax acetyl-CoA synthetase, putative 0.0027 0.0124 0.1721
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.01 0.0663 0.0971
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Brugia malayi PHD-finger family protein 0.0024 0.0099 0.015
Loa Loa (eye worm) hypothetical protein 0.0197 0.1386 0.2056
Echinococcus granulosus expressed conserved protein 0.0089 0.0586 0.0547
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0257 0.0229
Schistosoma mansoni heat shock protein 0.005 0.0288 0.026
Plasmodium falciparum phd finger protein, putative 0.0024 0.0101 0.1114
Leishmania major DNA topoisomerase ii 0.005 0.0288 0.0397
Plasmodium vivax hypothetical protein, conserved 0.005 0.0288 0.6029
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Entamoeba histolytica hypothetical protein 0.007 0.0445 0.6765
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0027 0.0124 0.0119
Loa Loa (eye worm) hypothetical protein 0.0027 0.0124 0.0119
Echinococcus granulosus tumor protein p63 0.0327 0.2357 0.2325
Trypanosoma brucei developmentally regulated phosphoprotein 0.089 0.656 1
Plasmodium falciparum JmjC domain-containing protein, putative 0.0024 0.0097 0.1014
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0124 0.1178
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Toxoplasma gondii PHD-finger domain-containing protein 0.0024 0.0101 0.0167
Trichomonas vaginalis antibiotic synthetase, putative 0.0027 0.0124 0.0419
Toxoplasma gondii heat shock protein HSP90 0.005 0.0288 0.0903
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0124 0.0189
Schistosoma mansoni ap endonuclease 0.0019 0.0058 0.0029
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.005 0.0288 0.4125
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.01 0.0663 0.0971
Onchocerca volvulus 0.0031 0.0152 0.0334
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0082 0.004
Mycobacterium ulcerans DNA gyrase subunit B 0.005 0.0288 0.4125
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0027 0.0124 0.0145
Schistosoma mansoni hypothetical protein 0.0134 0.0922 0.0895
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0058 0.0016
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0027 0.0124 0.1178
Echinococcus multilocularis heat shock protein 90 0.005 0.0288 0.0247
Schistosoma mansoni ap endonuclease 0.0019 0.0058 0.0029
Onchocerca volvulus 0.0229 0.1628 1
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.005 0.0288 0.4125
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.005 0.0288 0.4125
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0124 0.0522
Schistosoma mansoni hypothetical protein 0.0039 0.0213 0.0184
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0616 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.01 0.0663 0.0971
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0224 0.0183
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0197 0.1386 0.2112
Onchocerca volvulus 0.0055 0.0329 0.1494
Loa Loa (eye worm) hypothetical protein 0.007 0.044 0.0604
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.005 0.0288 0.1467
Echinococcus granulosus geminin 0.0168 0.1172 0.1134
Schistosoma mansoni jumonji domain containing protein 0.0024 0.0097 0.0068
Trypanosoma cruzi heat shock protein 90, putative 0.005 0.0288 0.0397
Mycobacterium tuberculosis Conserved protein 0.005 0.0288 0.4125
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0027 0.0124 0.0119
Onchocerca volvulus 0.0029 0.0134 0.0221
Echinococcus multilocularis heat shock protein 0.005 0.0288 0.0247
Loa Loa (eye worm) jmjC domain-containing protein 0.0091 0.0599 0.0849
Brugia malayi jmjC domain containing protein 0.0091 0.0599 0.0914
Echinococcus granulosus phd:f box containing protein 0.0024 0.0097 0.0055
Plasmodium vivax heat shock protein 86, putative 0.005 0.0288 0.6029
Plasmodium vivax DNA topoisomerase II, putative 0.005 0.0288 0.6029
Trichomonas vaginalis DNA topoisomerase II, putative 0.005 0.0288 0.1467
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.0934 0.0896
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0027 0.0124 0.0082
Plasmodium falciparum DNA topoisomerase 2 0.005 0.0288 0.6029
Brugia malayi Probable DNA topoisomerase II 0.005 0.0288 0.044
Leishmania major acetyl-CoA synthetase, putative 0.0027 0.0124 0.0145
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0412 0.6333
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0027 0.0124 0.0145
Echinococcus multilocularis phd:f box containing protein 0.0024 0.0097 0.0055
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0027 0.0124 0.0145
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.005 0.0288 0.4125
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Echinococcus multilocularis JmjC domain containing protein 4 0.0024 0.0097 0.0055
Trichomonas vaginalis endoplasmin, putative 0.005 0.0288 0.1467
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0094 0.0616 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.01 0.0663 0.0624
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0024 0.0097 0.0068
Echinococcus multilocularis expressed conserved protein 0.0089 0.0586 0.0547
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0027 0.0124 0.1178
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.014 0.0961 0.0922
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0094 0.0616 1
Plasmodium vivax DNA gyrase subunit B, putative 0.005 0.0288 0.6029
Leishmania major acetyl-CoA synthetase, putative 0.0027 0.0124 0.0145
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.038 0.0352
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.035 0.0309
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0134 0.0299
Brugia malayi Endoplasmin precursor 0.005 0.0288 0.044
Loa Loa (eye worm) hypothetical protein 0.0058 0.0349 0.0465
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0361 0.261 1
Onchocerca volvulus Huntingtin homolog 0.014 0.096 0.5625
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0027 0.0124 0.0522
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.038 0.5771
Echinococcus granulosus JmjC domain containing protein 4 0.0024 0.0097 0.0055
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0329 0.0501
Echinococcus granulosus mitogen activated protein kinase 3 0.01 0.0663 0.0624
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0134 0.0105
Echinococcus multilocularis PHD finger protein rhinoceros 0.0024 0.0101 0.0059
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0027 0.0124 0.0258
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.089 0.656 0.6546
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.038 0.034
Echinococcus granulosus DNA topoisomerase 2 alpha 0.005 0.0288 0.0247
Loa Loa (eye worm) hypothetical protein 0.0094 0.0616 0.0875
Brugia malayi jmjC domain containing protein 0.0024 0.0097 0.0147
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0058 0.0044
Mycobacterium tuberculosis Two component sensor kinase MprB 0.005 0.0288 0.4125
Schistosoma mansoni hypothetical protein 0.0024 0.0101 0.0071
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0134 0.0105
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.005 0.0288 0.4125
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.005 0.0288 0.0397
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0124 0.1178
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0062 0.0383 0.0342
Loa Loa (eye worm) heat shock protein 90 0.005 0.0288 0.0371
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0126 0.0085
Schistosoma mansoni pyruvate dehydrogenase 0.0841 0.6191 0.618
Leishmania major hypothetical protein, conserved 0.005 0.0288 0.0397
Loa Loa (eye worm) hypothetical protein 0.0269 0.1928 0.2888
Echinococcus multilocularis peregrin 0.0027 0.0118 0.0076
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.0629 1
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.0551 0.0839
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0024 0.0097 0.0152
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0077
Onchocerca volvulus Huntingtin homolog 0.014 0.096 0.5625
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.038 0.5771
Entamoeba histolytica hypothetical protein 0.007 0.0445 0.6765
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Onchocerca volvulus 0.0027 0.0124 0.0152
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.005 0.0288 0.3689
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.038 0.0352
Echinococcus multilocularis GPCR, family 2 0.0062 0.0383 0.0342
Leishmania major hypothetical protein, conserved 0.0024 0.0097 0.0103
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0062 0.0383 0.0584
Plasmodium falciparum endoplasmin, putative 0.005 0.0288 0.6029
Mycobacterium leprae Probable two-component sensor kinase 0.005 0.0288 0.3689
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0124 0.0189
Mycobacterium ulcerans acetyl-CoA synthetase 0.0027 0.0124 0.1178
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0024 0.0097 0.0103
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0027 0.0124 0.1178
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0027 0.0124 0.1178
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Echinococcus multilocularis survival motor neuron protein 1 0.0269 0.1928 0.1894
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0311 0.2241 0.3386
Trypanosoma brucei heat shock protein, putative 0.005 0.0288 0.0397
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0616 0.094
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.005 0.0288 0.0397
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.01 0.0663 0.0971
Loa Loa (eye worm) hypothetical protein 0.0062 0.0383 0.0517
Trichomonas vaginalis receptor histidine kinase, putative 0.005 0.0288 0.1467
Toxoplasma gondii heat shock protein 90, putative 0.005 0.0288 0.0903
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.005 0.0288 0.4125
Leishmania major developmentally regulated phosphoprotein-like protein 0.089 0.656 1
Trypanosoma brucei heat shock protein 90, putative 0.005 0.0288 0.0397
Echinococcus granulosus peregrin 0.0027 0.0118 0.0076
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0042 0.0013
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.005 0.0288 0.123
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0616 0.0899
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0257 0.0229
Schistosoma mansoni pyruvate dehydrogenase 0.0841 0.6191 0.618
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.038 0.5771
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0663 0.3855
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0097 0.0077
Echinococcus multilocularis geminin 0.0168 0.1172 0.1134
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.014 0.0961 0.0922
Trypanosoma cruzi heat shock protein 90, putative 0.005 0.0288 0.0397
Brugia malayi jmjC domain containing protein 0.0024 0.0097 0.0147
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0027 0.0124 0.1178
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0027 0.0124 0.0145
Echinococcus granulosus lysine specific demethylase 6a 0.0024 0.0097 0.0055
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0224 0.0183
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0785 0.577 0.5752
Onchocerca volvulus 0.0027 0.0124 0.0152
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.005 0.0288 0.1467
Mycobacterium ulcerans putative regultory protein 0.005 0.0288 0.4125
Echinococcus granulosus PHD finger protein rhinoceros 0.0024 0.0101 0.0059
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0124 0.0189
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.0629 0.059
Echinococcus multilocularis jumonji domain containing 1A 0.0024 0.0097 0.0055
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0124 0.1178
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.005 0.0288 0.4125
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.038 0.0537
Onchocerca volvulus 0.0027 0.0124 0.0152
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0124 0.1178
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0062 0.0383 0.0342
Echinococcus multilocularis lysine specific demethylase 5A 0.0089 0.0586 0.0546
Loa Loa (eye worm) hypothetical protein 0.014 0.096 0.1402
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.005 0.0288 0.6029
Mycobacterium leprae Probable two component sensor kinase MprB 0.005 0.0288 0.3689
Echinococcus granulosus lysine specific demethylase 5A 0.0091 0.0599 0.056
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0616 1
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.0551 0.0511
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.005 0.0288 0.4125
Schistosoma mansoni microtubule-associated protein tau 0.1352 1 1
Schistosoma mansoni hypothetical protein 0.007 0.0445 0.0416
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0062 0.0383 0.0342
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.038 0.1263
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.007 0.044 0.6843
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0097 0.0151
Loa Loa (eye worm) jmjC domain-containing protein 0.005 0.0294 0.038
Onchocerca volvulus 0.0085 0.0551 0.2946
Schistosoma mansoni hypothetical protein 0.0039 0.0213 0.0184
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.005 0.0288 0.4125
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.0629 0.059
Trypanosoma brucei heat shock protein 90, putative 0.005 0.0288 0.0397
Mycobacterium tuberculosis Possible two component sensor kinase 0.005 0.0288 0.4125
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0616 0.0899
Brugia malayi jmjC domain containing protein 0.014 0.0961 0.1464
Schistosoma mansoni hypothetical protein 0.0055 0.0329 0.03
Echinococcus granulosus jumonji domain containing protein 0.0034 0.0172 0.013
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0178 0.0137
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0311 0.2241 0.3386
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0045 0.0257 0.0216
Schistosoma mansoni transcription factor LCR-F1 0.007 0.0445 0.0416
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0082 0.004
Trypanosoma brucei Heat shock protein 83, putative 0.005 0.0288 0.0397
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0062 0.0383 0.0342
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.005 0.0288 0.0903
Trypanosoma cruzi DNA topoisomerase II, putative 0.005 0.0288 0.0397
Brugia malayi Bromodomain containing protein 0.0037 0.0195 0.0298
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0094 0.0616 1
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0027 0.0124 0.1178
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0083
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0027 0.0124 0.0145
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0097 0.0692
Trypanosoma cruzi Heat shock protein 83, putative 0.005 0.0288 0.0397
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.0629 0.0959
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0058 0.0018
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0026 0.011 0.0069
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0027 0.0124 0.0082
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.005 0.0288 1
Plasmodium vivax JmjC domain containing protein 0.0024 0.0097 0.1014
Schistosoma mansoni phosphatidylserine receptor 0.0024 0.0097 0.0068
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.005 0.0288 0.0397
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.005 0.0288 0.1467
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.005 0.0288 0.4125
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0024 0.0097 0.0103
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0097 0.0692
Brugia malayi latrophilin 2 splice variant baaae 0.0134 0.0922 0.1405
Brugia malayi Bromodomain containing protein 0.0073 0.046 0.0701
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0178 0.0137
Trichomonas vaginalis set domain proteins, putative 0.0229 0.1628 1
Leishmania major heat shock protein 83-1 0.005 0.0288 0.0397
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.005 0.0288 0.0247
Schistosoma mansoni endoplasmin 0.005 0.0288 0.026
Giardia lamblia Kinase, CMGC MAPK 0.01 0.0663 1
Loa Loa (eye worm) oxidoreductase 0.0027 0.0124 0.0119
Treponema pallidum chemotaxis histidine kinase (cheA) 0.005 0.0288 1
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0068 0.0033
Trypanosoma cruzi DNA topoisomerase II, putative 0.005 0.0288 0.0397
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0097 0.0077
Plasmodium falciparum DNA gyrase subunit B 0.005 0.0288 0.6029
Echinococcus multilocularis microtubule associated protein 2 0.1352 1 1
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.005 0.0288 0.4125
Schistosoma mansoni pyruvate dehydrogenase 0.089 0.656 0.655
Brugia malayi MAP kinase sur-1 0.01 0.0663 0.1011
Schistosoma mansoni protein phosphatase 2C 0.0024 0.0097 0.0068
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.007 0.044 1
Entamoeba histolytica hypothetical protein 0.007 0.0445 0.6765
Giardia lamblia PHD finger protein 15 0.0024 0.0101 0.0703
Onchocerca volvulus DNA topoisomerase 2 homolog 0.005 0.0288 0.123
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.089 0.656 0.6546
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.005 0.0288 0.4125
Brugia malayi heat shock protein 90 0.005 0.0288 0.044
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0026 0.011 0.0069
Schistosoma mansoni bromodomain containing protein 0.0061 0.0376 0.0347
Schistosoma mansoni hypothetical protein 0.0168 0.1172 0.1146
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0616 0.0899
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0027 0.0124 0.0145
Brugia malayi hypothetical protein 0.014 0.096 0.1463
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.038 0.5771
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.01 0.0663 0.0971
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0101 0.1114
Echinococcus multilocularis protein patched 0.0041 0.0224 0.0183
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.005 0.0288 0.1467
Loa Loa (eye worm) hypothetical protein 0.0048 0.0276 0.0352
Schistosoma mansoni survival motor neuron protein 0.0055 0.0329 0.03
Giardia lamblia Heat shock protein HSP 90-alpha 0.005 0.0288 0.3806

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.