Detailed information for compound 579250

Basic information

Technical information
  • TDR Targets ID: 579250
  • Name: 1H-indole-6-carboxamidine
  • MW: 159.188 | Formula: C9H9N3
  • H donors: 2 H acceptors: 0 LogP: 1.01 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC(=N)c1ccc2c(c1)[nH]cc2
  • InChi: 1S/C9H9N3/c10-9(11)7-2-1-6-3-4-12-8(6)5-7/h1-5,12H,(H3,10,11)
  • InChiKey: DJLHTAIFMAKJST-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1H-indole-6-carboximidamide
  • 6-amidinoindole
  • 71889-72-0

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.001 0.0012
Onchocerca volvulus 0.0091 0.0136 0.1081
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0184
Loa Loa (eye worm) heat shock protein 90 0.0034 0.003 0.0237
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0172 0.0286 0.0286
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0042 0.0052
Brugia malayi Patched protein homolog 1 0.0027 0.0017 0.0142
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0091 0.0136 0.1134
Echinococcus multilocularis protein patched 0.0192 0.0323 0.0323
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0065 0.0089 0.0089
Echinococcus granulosus geminin 0.1069 0.1959 0.2408
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Trichomonas vaginalis aldo-keto reductase, putative 0.0313 0.055 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0052 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0065 0.0089 0.074
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Trypanosoma brucei Heat shock protein 83, putative 0.0034 0.003 0.0379
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0127 0.0204 0.025
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0065 0.0088 0.0352
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0065 0.0089 0.0109
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.001 0.019
Loa Loa (eye worm) oxidoreductase 0.0313 0.055 0.4594
Entamoeba histolytica hypothetical protein 0.0026 0.0014 0.0056
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0126 0.0201 0.0801
Treponema pallidum DNA ligase (lig) 0.0065 0.0088 0.3212
Trichomonas vaginalis aldo-keto reductase, putative 0.0313 0.055 1
Giardia lamblia Kinase, CMGC MAPK 0.0058 0.0074 0.1189
Mycobacterium tuberculosis Conserved protein 0.0091 0.0136 0.054
Loa Loa (eye worm) ICD-1 protein 0.0072 0.01 0.0821
Echinococcus multilocularis heat shock protein 0.0034 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0036 0.0279
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0031 0.0024 0.0024
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0106 0.0163 0.284
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0052 0.0063
Plasmodium vivax metacaspase 1, putative 0.014 0.0227 1
Trypanosoma brucei heat shock protein, putative 0.0034 0.003 0.0379
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0297 0.052 0.9449
Plasmodium falciparum metacaspase-like protein 0.014 0.0227 1
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0037 0.0036 0.0142
Brugia malayi serine/threonine-protein kinase plk-2 0.0106 0.0163 0.1366
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Trypanosoma cruzi aldo-keto reductase 0.0313 0.055 1
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.0036 0.0473
Echinococcus granulosus RUN 0.0022 0.0007 0.0009
Schistosoma mansoni topbp1 0.0065 0.0088 0.0109
Loa Loa (eye worm) hypothetical protein 0.0022 0.0007 0.0042
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0172 0.0286 0.0352
Loa Loa (eye worm) DR-78 0.0031 0.0024 0.0184
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.01 0.1821
Schistosoma mansoni hypothetical protein 0.0185 0.0311 0.0382
Brugia malayi nuclear hormone receptor family member odr-7 0.0031 0.0024 0.0201
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0767 0.1395 0.5551
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0172 0.0286 0.0352
Toxoplasma gondii propionate-CoA ligase 0.0037 0.0036 0.0473
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0035 0.0031 0.0031
Echinococcus granulosus cpg binding protein 0.0065 0.0088 0.0108
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.003 0.0379
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0065 0.0088 0.0634
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0065 0.0089 0.0109
Onchocerca volvulus Huntingtin homolog 0.0659 0.1195 1
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.0036 0.0573
Toxoplasma gondii aldose reductase, putative 0.0313 0.055 1
Schistosoma mansoni hypothetical protein 0.0034 0.003 0.0037
Loa Loa (eye worm) hypothetical protein 0.0479 0.0859 0.7185
Trypanosoma cruzi polo-like protein kinase, putative 0.0106 0.0163 0.2914
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0227 0.4124
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0042 0.0694
Onchocerca volvulus 0.0126 0.0201 0.1634
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0024 0.003
Brugia malayi Myosin head containing protein 0.0027 0.0017 0.0142
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0065 0.0089 0.0109
Schistosoma mansoni topbp1 0.0065 0.0088 0.0109
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0161 0.0267 0.0328
Entamoeba histolytica serine/threonine protein kinase, putative 0.0106 0.0163 0.1946
Loa Loa (eye worm) hypothetical protein 0.0211 0.0359 0.2993
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0313 0.055 1
Echinococcus granulosus nibrin 0.0065 0.0088 0.0109
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0108 0.0167 0.14
Trypanosoma brucei heat shock protein, putative 0.0034 0.003 0.0379
Loa Loa (eye worm) hypothetical protein 0.0159 0.0263 0.2189
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0091 0.0136 0.1119
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0036 0.0573
Loa Loa (eye worm) nuclear hormone receptor 0.0031 0.0024 0.0184
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0166 0.0275 0.5009
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0037 0.0036 0.0296
Loa Loa (eye worm) hypothetical protein 0.0035 0.0031 0.0242
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0313 0.055 0.0676
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0036 0.0296
Echinococcus granulosus endoplasmin 0.0027 0.0017 0.0021
Onchocerca volvulus 0.0027 0.0017 0.0083
Loa Loa (eye worm) hypothetical protein 0.013 0.0209 0.1733
Schistosoma mansoni hypothetical protein 0.0185 0.0311 0.0382
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0065 0.0089 0.0109
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0446 0.0798 1
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0313 0.055 0.4603
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0052 0.0063
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0019 0.0261
Schistosoma mansoni inositol monophosphatase 0.0041 0.0043 0.0053
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0089 0.0132 0.0527
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0043 0.0415
Schistosoma mansoni cellular tumor antigen P53 0.0211 0.0359 0.0441
Loa Loa (eye worm) hypothetical protein 0.0659 0.1195 1
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0037 0.0036 0.1347
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0227 0.4124
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0043 0.0053
Onchocerca volvulus 0.0062 0.0082 0.0627
Trypanosoma brucei heat shock protein, putative 0.0034 0.003 0.0379
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0058 0.0074 0.0603
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0058 0.0074 0.1189
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Brugia malayi hypothetical protein 0.0035 0.0031 0.0259
Echinococcus multilocularis aldo keto reductase 0.0313 0.055 0.055
Echinococcus granulosus snurportin 1 0.0337 0.0595 0.0732
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0037 0.0036 0.0142
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0052 0.0063
Schistosoma mansoni hypothetical protein 0.0022 0.0007 0.0009
Plasmodium falciparum importin beta, putative 0.0032 0.0026 0.0894
Schistosoma mansoni hypothetical protein 0.1069 0.1959 0.2408
Schistosoma mansoni aldo-keto reductase 0.0313 0.055 0.0676
Plasmodium vivax acetyl-CoA synthetase, putative 0.0037 0.0036 0.1289
Plasmodium falciparum acyl-CoA synthetase 0.0094 0.0142 0.6164
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.003 0.0037
Schistosoma mansoni lipoxygenase 0.0022 0.0007 0.0009
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0036 0.0142
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0042 0.0042
Mycobacterium leprae Possible oxidoreductase 0.0091 0.0136 0.0972
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0163 0.297
Leishmania major aldo-keto reductase-like protein 0.0313 0.055 1
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0369 0.0654 0.0654
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0065 0.0089 0.0109
Echinococcus granulosus Niemann Pick C1 protein 0.0638 0.1155 0.142
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0088 0.1609
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0227 0.4124
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0035 0.0031 0.0242
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0037 0.0036 0.0142
Echinococcus granulosus caspase 2 0.027 0.0469 0.0577
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0313 0.055 0.0676
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0074 0.1349
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0024 0.0201
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0065 0.0089 0.0724
Loa Loa (eye worm) hypothetical protein 0.0041 0.0042 0.0335
Echinococcus granulosus importin subunit beta 1 0.0032 0.0026 0.0031
Giardia lamblia Grp94/Hsp90 0.0027 0.0017 0.0138
Schistosoma mansoni retinoic acid receptor RXR 0.0065 0.0089 0.0109
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.1367 0.2513 1
Trichomonas vaginalis aldo/keto reductase, putative 0.0313 0.055 1
Schistosoma mansoni thyroid hormone receptor 0.0065 0.0089 0.0109
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Echinococcus granulosus caspase 3 0.023 0.0394 0.0485
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0037 0.0036 0.0142
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.003 0.0234
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0037 0.0036 0.0044
Onchocerca volvulus 0.0048 0.0056 0.0412
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0062 0.0246
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0089 0.0132 0.0527
Brugia malayi hypothetical protein 0.0659 0.1195 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0007 0.0009
Brugia malayi Patched related family protein 4 0.0027 0.0017 0.0142
Loa Loa (eye worm) hypothetical protein 0.0028 0.0019 0.0137
Schistosoma mansoni hypothetical protein 0.0185 0.0311 0.0382
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Schistosoma mansoni caspase-7 (C14 family) 0.027 0.0469 0.0577
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Echinococcus granulosus Protein patched homolog 1 0.0192 0.0323 0.0398
Mycobacterium ulcerans oxidoreductase 0.0313 0.055 0.2188
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0065 0.0089 0.0089
Brugia malayi nuclear hormone receptor family member nhr-6 0.0031 0.0024 0.0201
Loa Loa (eye worm) patched family protein 0.0027 0.0017 0.0124
Loa Loa (eye worm) patched family protein 0.0027 0.0017 0.0124
Echinococcus multilocularis sterol regulatory element binding protein 0.0192 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0227 0.4124
Echinococcus granulosus sterol regulatory element binding protein 0.0192 0.0323 0.0398
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0052 0.0052
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0065 0.0089 0.074
Mycobacterium ulcerans thymidine phosphorylase 0.1367 0.2513 1
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0062 0.0062
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0042 0.0042
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0065 0.0089 0.0109
Echinococcus granulosus aldo keto reductase 0.0313 0.055 0.0676
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0091 0.0136 0.2466
Mycobacterium ulcerans hypothetical protein 0.0091 0.0136 0.054
Onchocerca volvulus Protein patched homolog 0.0027 0.0017 0.0083
Trypanosoma cruzi metacaspase, putative 0.014 0.0227 0.4077
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.0386 0.0685 0.4914
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0479 0.0859 0.7185
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0163 0.297
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0184
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0037 0.0036 0.0142
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.003 0.0259
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0043 0.017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0065 0.0089 0.0724
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0035 0.0031 0.0038
Schistosoma mansoni thyroid hormone receptor 0.0065 0.0089 0.0109
Schistosoma mansoni pol-related 0.0313 0.055 0.0676
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0066 0.1199
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0074 0.0091
Loa Loa (eye worm) hypothetical protein 0.0065 0.0088 0.0723
Loa Loa (eye worm) hypothetical protein 0.0094 0.0142 0.1172
Loa Loa (eye worm) hypothetical protein 0.0037 0.0036 0.0279
Onchocerca volvulus Serine\/threonine kinase homolog 0.0106 0.0163 0.1314
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0078 0.0112 0.0801
Schistosoma mansoni kinase 0.0055 0.0068 0.0084
Loa Loa (eye worm) hypothetical protein 0.0235 0.0404 0.3367
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0043 0.0704
Echinococcus multilocularis cpg binding protein 0.0065 0.0088 0.0088
Onchocerca volvulus 0.013 0.0209 0.1698
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0126 0.0201 0.0801
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0088 0.1609
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0037 0.0036 0.0142
Brugia malayi follicle stimulating hormone receptor 0.0246 0.0426 0.3562
Trichomonas vaginalis aldo-keto reductase, putative 0.0313 0.055 1
Mycobacterium ulcerans heat shock protein 90 0.0027 0.0017 0.0069
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0065 0.0089 0.0109
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0002 0.0014
Schistosoma mansoni hypothetical protein 0.0879 0.1605 0.1972
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0313 0.055 0.055
Schistosoma mansoni hypothetical protein 0.0074 0.0104 0.0128
Onchocerca volvulus 0.0049 0.0058 0.0429
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0206 0.0351 0.2923
Brugia malayi heat shock protein 90 0.0034 0.003 0.0253
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.001 0.0065
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0035 0.0031 0.0038
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0065 0.0089 0.0089
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0091 0.0136 0.5847
Loa Loa (eye worm) hypothetical protein 0.0065 0.0088 0.0723
Echinococcus multilocularis nuclear receptor nhr 48 0.0031 0.0024 0.0024
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0126 0.0201 0.0801
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.0088 0.1542
Echinococcus multilocularis musashi 0.0028 0.002 0.002
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0297 0.052 0.9454
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.014 0.0227 0.4015
Schistosoma mansoni zinc finger protein 0.0031 0.0024 0.003
Schistosoma mansoni cpg binding protein 0.0065 0.0088 0.0108
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0043 0.0777
Echinococcus multilocularis thymidine phosphorylase 0.1367 0.2513 0.2513
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0065 0.0089 0.074
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0017 0.0318
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0036 0.0142
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.0036 0.0647
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Loa Loa (eye worm) hypothetical protein 0.0094 0.0142 0.1172
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0065 0.0089 0.0109
Loa Loa (eye worm) hypothetical protein 0.0108 0.0167 0.1385
Toxoplasma gondii ATPase, AAA family protein 0.0065 0.0088 0.1454
Brugia malayi Latrophilin receptor protein 2 0.0034 0.003 0.0251
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0065 0.0088 0.0739
Echinococcus granulosus Niemann Pick C1 protein 0.0446 0.0798 0.0981
Plasmodium vivax replication factor C subunit 1, putative 0.0065 0.0088 0.37
Onchocerca volvulus 0.0028 0.002 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0088 0.1609
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0724
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0035 0.0138
Brugia malayi hypothetical protein 0.0027 0.0017 0.0142
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0106 0.0163 0.0201
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0089 0.0109
Echinococcus multilocularis tumor protein p63 0.1439 0.2648 0.2648
Entamoeba histolytica protein kinase, putative 0.0297 0.052 0.6474
Echinococcus multilocularis muscleblind protein 1 0.0479 0.0859 0.0859
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0106 0.0163 0.1351
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0042 0.0052
Schistosoma mansoni hypothetical protein 0.013 0.0209 0.0257
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0036 0.0142
Schistosoma mansoni cpg binding protein 0.0062 0.0082 0.01
Brugia malayi hypothetical protein 0.0027 0.0017 0.0142
Brugia malayi tailless protein 0.0031 0.0024 0.0201
Loa Loa (eye worm) hypothetical protein 0.0659 0.1195 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0074 0.1281
Echinococcus multilocularis geminin 0.1069 0.1959 0.1959
Brugia malayi conserved hypotetical protein 0.0031 0.0024 0.0201
Echinococcus granulosus aldo keto reductase 0.0313 0.055 0.0676
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0017 0.0427
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0043 0.0606
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Onchocerca volvulus 0.0027 0.0017 0.0083
Trypanosoma cruzi metacaspase, putative 0.014 0.0227 0.4077
Schistosoma mansoni polycystin 1-related 0.0022 0.0007 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.01 0.1821
Onchocerca volvulus Protein ultraspiracle homolog 0.0065 0.0089 0.0685
Brugia malayi hypothetical protein 0.0028 0.0019 0.0154
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0065 0.0089 0.074
Trichomonas vaginalis aldo-keto reductase, putative 0.0313 0.055 1
Loa Loa (eye worm) TAR-binding protein 0.0206 0.0351 0.2923
Trichomonas vaginalis conserved hypothetical protein 0.0192 0.0323 0.5881
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Brugia malayi nuclear receptor NHR-88 0.0065 0.0089 0.074
Echinococcus multilocularis lamin 0.0028 0.002 0.002
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0369 0.0654 0.0804
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0031 0.0259
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0065 0.0089 0.0089
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Trypanosoma brucei prostaglandin f synthase 0.0313 0.055 1
Entamoeba histolytica hypothetical protein 0.0161 0.0267 0.3263
Echinococcus granulosus neuropeptide s receptor 0.0466 0.0835 0.1027
Brugia malayi Cell death protein 3 precursor 0.027 0.0469 0.3925
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0313 0.055 0.0676
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0065 0.0089 0.0724
Loa Loa (eye worm) hypothetical protein 0.0094 0.0142 0.1172
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0112 0.4056
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0006 0.0105
Schistosoma mansoni caspase-3 (C14 family) 0.0369 0.0654 0.0804
Schistosoma mansoni hypothetical protein 0.0337 0.0595 0.0732
Brugia malayi AMP-binding enzyme family protein 0.0126 0.0201 0.1684
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0065 0.0088 0.1609
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0313 0.055 0.055
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Echinococcus granulosus lamin 0.0028 0.002 0.0024
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.003 0.0479
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0065 0.0089 0.0724
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0227 0.4124
Echinococcus granulosus neuropeptide receptor A26 0.0466 0.0835 0.1027
Trypanosoma cruzi metacaspase 5, putative 0.014 0.0227 0.4077
Echinococcus granulosus GPCR family 2 0.0034 0.003 0.0037
Mycobacterium ulcerans hypothetical protein 0.0126 0.0201 0.0801
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0036 0.0142
Echinococcus multilocularis dnaJ subfamily B 0.0879 0.1605 0.1605
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0007 0.0067
Schistosoma mansoni heat shock protein 0.0034 0.003 0.0037
Trypanosoma brucei polo-like protein kinase 0.0106 0.0163 0.284
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0024 0.003
Brugia malayi hypothetical protein 0.0159 0.0263 0.2202
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0313 0.055 0.0676
Echinococcus multilocularis Niemann Pick C1 protein 0.0446 0.0798 0.0798
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0042 0.0767
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0042 0.0052
Leishmania major 4-coumarate:coa ligase-like protein 0.0126 0.0201 0.3543
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0108 0.0167 0.1385
Trypanosoma cruzi FHA domain containing protein, putative 0.0065 0.0088 0.1542
Onchocerca volvulus 0.0037 0.0036 0.0238
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.001 0.0104
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0297 0.052 0.9454
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0036 0.0142
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.003 0.003
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0112 0.4346
Trypanosoma cruzi metacaspase, putative 0.014 0.0227 0.4077
Echinococcus multilocularis dual specificity 0.0297 0.052 0.052
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0036 0.0142
Entamoeba histolytica alcohol dehydrogenase, putative 0.0091 0.0136 0.1594
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0019 0.0159
Echinococcus multilocularis snurportin 1 0.0337 0.0595 0.0595
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0136 0.2466
Loa Loa (eye worm) oxidoreductase 0.0313 0.055 0.4594
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0184
Schistosoma mansoni hypothetical protein 0.0048 0.0056 0.0069
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0094 0.0142 0.0565
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0313 0.055 0.055
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0313 0.055 0.055
Brugia malayi NADH-dependent xylose reductase 0.0091 0.0136 0.1134
Echinococcus multilocularis mitogen activated protein kinase 0.0058 0.0074 0.0074
Echinococcus multilocularis Niemann Pick C1 protein 0.0638 0.1155 0.1155
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0127 0.0204 0.3586
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0034 0.003 0.0037
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0026 0.0026
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0078 0.0112 1
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0106 0.0163 0.0163
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0088 0.1609
Echinococcus multilocularis caspase 2 0.027 0.0469 0.0469
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0052 0.0413
Brugia malayi hypothetical protein 0.0022 0.0007 0.0059
Mycobacterium ulcerans acyl-CoA synthetase 0.0126 0.0201 0.0801
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0313 0.055 0.055
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0037 0.0036 0.0036
Trypanosoma cruzi heat shock protein 90, putative 0.0027 0.0017 0.0241
Echinococcus granulosus aldehyde reductase 0.0222 0.0381 0.0468
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0026 0.0288
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0037 0.0036 0.0142
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0037 0.0036 0.0473
Toxoplasma gondii aldo-keto reductase 0.0091 0.0136 0.2326
Schistosoma mansoni lipoxygenase 0.0061 0.008 0.0099
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0172 0.0286 0.0352
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0184
Echinococcus granulosus hypothetical protein 0.0313 0.055 0.0676
Echinococcus multilocularis endoplasmin 0.0027 0.0017 0.0017
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0037 0.0036 0.0473
Echinococcus multilocularis lamin dm0 0.0028 0.002 0.002
Echinococcus granulosus tar DNA binding protein 0.0206 0.0351 0.0431
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0074 0.1349
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0031 0.0024 0.003
Plasmodium falciparum metacaspase 1 0.014 0.0227 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0031 0.0242
Brugia malayi Patched related family protein 12 0.0027 0.0017 0.0142
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0112 0.0445
Mycobacterium leprae Conserved hypothetical protein 0.0222 0.0381 0.2731
Loa Loa (eye worm) endoplasmin 0.0034 0.003 0.0237
Echinococcus granulosus dual specificity 0.0297 0.052 0.0639
Brugia malayi nuclear hormone receptor 0.0031 0.0024 0.0201
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0036 0.0142
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0185 0.3232
Echinococcus multilocularis voltage gated potassium channel subunit 0.0091 0.0136 0.0136
Loa Loa (eye worm) steroid hormone receptor 0.0065 0.0089 0.0724
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0042 0.0694
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Schistosoma mansoni tar DNA-binding protein 0.0206 0.0351 0.0431
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0014 0.0262
Echinococcus granulosus intermediate filament protein 0.0028 0.002 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0136 0.2466
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0042 0.0596
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0166 0.0275 0.3369
Schistosoma mansoni tar DNA-binding protein 0.0206 0.0351 0.0431
Echinococcus multilocularis caspase 8 0.014 0.0227 0.0227
Loa Loa (eye worm) oxidoreductase 0.0313 0.055 0.4594
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0062 0.0076
Onchocerca volvulus 0.0037 0.0036 0.0238
Toxoplasma gondii patched family protein 0.0027 0.0017 0.0131
Onchocerca volvulus 0.0065 0.0088 0.0684
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.0036 0.0473
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0042 0.0596
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0724
Leishmania major hypothetical protein, conserved 0.0028 0.0019 0.0159
Onchocerca volvulus Protein patched homolog 0.0027 0.0017 0.0083
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0313 0.055 0.055
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0017 0.0119
Brugia malayi hypothetical protein 0.0022 0.0007 0.0059
Loa Loa (eye worm) hypothetical protein 0.0126 0.0201 0.167
Plasmodium vivax acyl-CoA synthetase, putative 0.0094 0.0142 0.6138
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0031 0.0024 0.003
Leishmania major metacaspase, putative 0.014 0.0227 0.4015
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0126 0.0201 0.0801
Schistosoma mansoni chromosome transmission fidelity factor 0.0065 0.0088 0.0109
Schistosoma mansoni rab6-interacting 0.0022 0.0007 0.0009
Trichomonas vaginalis replication factor C large subunit, putative 0.0065 0.0088 0.1609
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0026 0.0288
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0166 0.0275 0.5009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Brugia malayi nuclear receptor RXR 0.0035 0.0031 0.0259
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0042 0.0408
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.001 0.0104
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0043 0.0704
Toxoplasma gondii hypothetical protein 0.0027 0.0017 0.0131
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0062 0.0246
Loa Loa (eye worm) nuclear receptor NHR-67 0.0031 0.0024 0.0184
Brugia malayi RNA recognition motif domain containing protein 0.0206 0.0351 0.2935
Plasmodium falciparum replication factor C subunit 1, putative 0.0065 0.0088 0.3742
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0065 0.0089 0.074
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0227 0.4124
Brugia malayi beta-NAC-like protein 0.0072 0.01 0.0837
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0065 0.0088 0.1453
Echinococcus granulosus heat shock protein 90 0.0034 0.003 0.0037
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0066 0.1199
Schistosoma mansoni microtubule-associated protein tau 0.4385 0.8135 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0043 0.0606
Trypanosoma brucei metacaspase MCA2 0.014 0.0227 0.4015
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0082 0.0666
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0163 0.0201
Loa Loa (eye worm) hypothetical protein 0.0295 0.0516 0.4307
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0019 0.0578
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0104 0.0868
Echinococcus multilocularis apoptotic protease activating factor 1 0.013 0.0209 0.0209
Treponema pallidum fructose-bisphosphate aldolase 0.0166 0.0275 1
Schistosoma mansoni caspase-7 (C14 family) 0.0369 0.0654 0.0804
Plasmodium falciparum basic transcription factor 3b, putative 0.0072 0.01 0.4269
Brugia malayi Nuclear hormone receptor-like 1 0.0065 0.0089 0.074
Toxoplasma gondii hypothetical protein 0.0027 0.0017 0.0123
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0724
Plasmodium falciparum heat shock protein 90 0.0034 0.003 0.1116
Brugia malayi nuclear receptor NHR-67 0.0031 0.0024 0.0201
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Brugia malayi CXXC zinc finger family protein 0.0062 0.0082 0.0682
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0227 0.4124
Schistosoma mansoni nuclear receptor nhr-48 0.0031 0.0024 0.003
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0019 0.0578
Trypanosoma cruzi Heat shock protein 83, putative 0.0034 0.003 0.0479
Brugia malayi Niemann-Pick C1 protein precursor 0.0446 0.0798 0.668
Schistosoma mansoni endoplasmin 0.0034 0.003 0.0037
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0065 0.0088 0.1542
Brugia malayi RNA binding protein 0.0206 0.0351 0.2935
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0166 0.0275 0.5009
Echinococcus multilocularis heat shock protein 90 0.0034 0.003 0.003
Onchocerca volvulus 0.0211 0.0359 0.2964
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0036 0.0142
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0037 0.0036 0.0142
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0031 0.0024 0.0184
Echinococcus granulosus FTZ F1 alpha 0.0065 0.0089 0.0109
Trichomonas vaginalis aldo-keto reductase, putative 0.0313 0.055 1
Brugia malayi Importin beta-1 subunit 0.0032 0.0026 0.0212
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0126 0.0201 0.1443
Echinococcus granulosus survival motor neuron protein 1 0.0235 0.0405 0.0498
Echinococcus multilocularis tar DNA binding protein 0.0206 0.0351 0.0351
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0014 0.0185
Brugia malayi Inositol-1 0.0041 0.0043 0.0356
Echinococcus multilocularis mitogen activated protein kinase 3 0.0058 0.0074 0.0074
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0007 0.0009
Entamoeba histolytica hypothetical protein 0.0072 0.01 0.1144
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0065 0.0089 0.0685
Brugia malayi hypothetical protein 0.0065 0.0088 0.0739
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0313 0.055 0.4603
Entamoeba histolytica alcohol dehydrogenase, putative 0.0091 0.0136 0.1594
Schistosoma mansoni inositol monophosphatase 0.0041 0.0043 0.0053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0065 0.0089 0.0724
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.014 0.0227 0.0279
Brugia malayi Steroid receptor seven-up type 2 0.0065 0.0089 0.074
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0094 0.0142 0.0565
Brugia malayi Doublecortin family protein 0.0022 0.0007 0.0059
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Trypanosoma cruzi aldo/keto reductase, putative 0.0091 0.0136 0.2406
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0037 0.0036 0.0255
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0163 0.297
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.003 0.0037
Plasmodium vivax importin-beta 2, putative 0.0032 0.0026 0.0833
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0065 0.0088 0.1609
Echinococcus multilocularis GPCR, family 2 0.0034 0.003 0.003
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Echinococcus multilocularis neuropeptide receptor A26 0.0466 0.0835 0.0835
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0065 0.0088 0.0996
Loa Loa (eye worm) hypothetical protein 0.0035 0.0031 0.0242
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Schistosoma mansoni hypothetical protein 0.0034 0.003 0.0037
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Brugia malayi hypothetical protein 0.0027 0.0017 0.0142
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0007 0.0007
Onchocerca volvulus Bile acid receptor homolog 0.0065 0.0089 0.0685
Brugia malayi protein C24B5.3 0.0027 0.0017 0.0142
Schistosoma mansoni importin beta-1 0.0032 0.0026 0.0031
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0184
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0127 0.0204 0.1703
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0024 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0065 0.0089 0.074
Trypanosoma brucei aldo/keto reductase, putative 0.0091 0.0136 0.2326
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.001 0.001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0037 0.0036 0.0296
Brugia malayi hypothetical protein 0.0031 0.0024 0.0201
Schistosoma mansoni cpg binding protein 0.0065 0.0088 0.0108
Onchocerca volvulus 0.0172 0.0286 0.235
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0065 0.0089 0.074
Echinococcus multilocularis aldehyde reductase 0.0222 0.0381 0.0381
Schistosoma mansoni tar DNA-binding protein 0.0206 0.0351 0.0431
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0042 0.0052
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Echinococcus multilocularis survival motor neuron protein 1 0.0235 0.0405 0.0405
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0065 0.0088 0.1609
Echinococcus granulosus thyroid hormone receptor alpha 0.0031 0.0024 0.003
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0112 0.1884
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0042 0.0352
Toxoplasma gondii patched family protein 0.0027 0.0017 0.0131
Loa Loa (eye worm) hypothetical protein 0.0313 0.055 0.4594
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.003 0.003
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0313 0.055 0.055
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.052 0.0639
Loa Loa (eye worm) hypothetical protein 0.0074 0.0104 0.0852
Trichomonas vaginalis aldo-keto reductase, putative 0.0313 0.055 1
Schistosoma mansoni ran 0.0023 0.001 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0065 0.0089 0.074
Trichomonas vaginalis aldo/keto reductase, putative 0.0313 0.055 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0166 0.0275 0.5009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0056 0.0469
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0184
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0036 0.0296
Schistosoma mansoni tar DNA-binding protein 0.0206 0.0351 0.0431
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0031 0.0024 0.003
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0027 0.0017 0.0021
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0127 0.0204 0.081
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0017 0.0491
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0112 0.4794
Loa Loa (eye worm) pip kinase 2 0.0172 0.0286 0.2382
Plasmodium vivax heat shock protein 86, putative 0.0034 0.003 0.1056
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0036 0.0142
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0031 0.0024 0.0024
Mycobacterium ulcerans acyl-CoA synthetase 0.0126 0.0201 0.0801
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0767 0.1395 0.5551
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0058 0.0074 0.1189
Onchocerca volvulus 0.0313 0.055 0.4571
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0724
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0145
Loa Loa (eye worm) hypothetical protein 0.0172 0.0286 0.2382
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0043 0.0777
Onchocerca volvulus 0.0031 0.0024 0.0142
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.0088 0.1542
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0017 0.0318
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0091 0.0136 0.2326
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0065 0.0088 0.7918
Giardia lamblia Heat shock protein HSP 90-alpha 0.0034 0.003 0.0379
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0089 0.0132 0.0527
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0163 0.297
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0042 0.0767
Schistosoma mansoni acetyl-CoA synthetase 0.0037 0.0036 0.0044
Brugia malayi AMP-binding enzyme family protein 0.0126 0.0201 0.1684
Trypanosoma brucei heat shock protein, putative 0.0034 0.003 0.0379
Trichomonas vaginalis aldo-keto reductase, putative 0.0313 0.055 1
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0078 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Trichomonas vaginalis aldo/keto reductase, putative 0.0313 0.055 1
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0112 0.4346
Brugia malayi hypothetical protein 0.0027 0.0017 0.0142
Plasmodium vivax patched family protein, putative 0.0027 0.0017 0.0447
Brugia malayi AMP-binding enzyme family protein 0.0126 0.0201 0.1684
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0026 0.0288
Mycobacterium ulcerans acetyl-CoA synthetase 0.0037 0.0036 0.0142
Brugia malayi hypothetical protein 0.0235 0.0405 0.3392
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0313 0.055 0.4603
Schistosoma mansoni hypothetical protein 0.0161 0.0267 0.0328
Plasmodium falciparum aldo-keto reductase, putative 0.0091 0.0136 0.5875
Loa Loa (eye worm) hypothetical protein 0.0094 0.0142 0.1172
Echinococcus multilocularis protein dispatched 1 0.0219 0.0374 0.0374
Onchocerca volvulus 0.0027 0.0017 0.0083
Leishmania major importin beta-1 subunit, putative 0.0026 0.0014 0.0082
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0024 0.0142
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0166 0.0275 0.5009
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0453 0.0811 0.0997
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0043 0.0606
Onchocerca volvulus Cell death protein 3 homolog 0.027 0.0469 0.3889
Loa Loa (eye worm) RNA binding protein 0.0206 0.0351 0.2923
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0052 0.043
Trypanosoma brucei transcription factor BTF3, putative 0.0072 0.01 0.1669
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0007 0.0009
Onchocerca volvulus 0.0027 0.0017 0.0083
Entamoeba histolytica hypothetical protein 0.0161 0.0267 0.3263
Loa Loa (eye worm) hypothetical protein 0.0094 0.0142 0.1172
Loa Loa (eye worm) hypothetical protein 0.0028 0.0019 0.0137
Onchocerca volvulus Huntingtin homolog 0.0659 0.1195 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0035 0.0031 0.0038
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Plasmodium falciparum aldehyde reductase, putative 0.0091 0.0136 0.5875
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0036 0.0296
Brugia malayi Patched related family protein 10 0.0027 0.0017 0.0142
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0065 0.0089 0.0089
Brugia malayi nuclear receptor NHR-88 0.0031 0.0024 0.0201
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0078 0.0112 0.0137
Echinococcus multilocularis aldo keto reductase 0.0313 0.055 0.055
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0163 0.297
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0313 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Toxoplasma gondii heat shock protein HSP90 0.0034 0.003 0.0379
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0065 0.0089 0.0109
Echinococcus granulosus dnaJ subfamily B 0.0879 0.1605 0.1972
Schistosoma mansoni nuclear receptor 0.0031 0.0024 0.003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0065 0.0089 0.0109
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0184
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Giardia lamblia Fructose-bisphosphate aldolase 0.0166 0.0275 0.4917
Echinococcus granulosus thymidine phosphorylase 0.1367 0.2513 0.3089
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0136 0.2466
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0131 0.0211 0.0259
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.001 0.0082
Onchocerca volvulus 0.0159 0.0263 0.2156
Brugia malayi MAP kinase sur-1 0.0058 0.0074 0.062
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0036 0.0142
Echinococcus multilocularis thyroid hormone receptor alpha 0.0065 0.0089 0.0089
Entamoeba histolytica aldose reductase, putative 0.0313 0.055 0.6852
Onchocerca volvulus 0.0313 0.055 0.4571
Echinococcus granulosus apoptotic protease activating factor 1 0.013 0.0209 0.0257
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Schistosoma mansoni peptidase Clp (S14 family) 0.0078 0.0112 0.0137
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0074 0.1281
Onchocerca volvulus 0.0065 0.0089 0.0685
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0724
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0037 0.0036 0.0142
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0313 0.055 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0088 0.0723
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0036 0.0473
Onchocerca volvulus 0.0027 0.0017 0.0083
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0027 0.0017 0.1563
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0127 0.0204 0.081
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Brugia malayi TAR-binding protein 0.0206 0.0351 0.2935
Brugia malayi hypothetical protein 0.0161 0.0267 0.2235
Loa Loa (eye worm) intermediate filament protein 0.0028 0.002 0.0145
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0037 0.0036 0.0142
Echinococcus granulosus heat shock protein 0.0034 0.003 0.0037
Echinococcus multilocularis RUN 0.0022 0.0007 0.0007
Entamoeba histolytica hypothetical protein 0.0161 0.0267 0.3263
Loa Loa (eye worm) hypothetical protein 0.0126 0.0201 0.167
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0184
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Schistosoma mansoni nuclear receptor 0.0031 0.0024 0.003
Echinococcus granulosus muscleblind protein 0.0479 0.0859 0.1056
Brugia malayi DKFZp564C0469 protein 0.0065 0.0088 0.0739
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0065 0.0089 0.074
Plasmodium falciparum lipid/sterol:H+ symporter 0.0027 0.0017 0.0511
Schistosoma mansoni hypothetical protein 0.0185 0.0311 0.0382
Plasmodium vivax endoplasmin, putative 0.0034 0.003 0.1056
Onchocerca volvulus 0.0037 0.0036 0.0238
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.001 0.0124
Loa Loa (eye worm) hypothetical protein 0.0022 0.0007 0.0042
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.0386 0.0685 0.2727
Giardia lamblia Kinase, PLK 0.0106 0.0163 0.284
Brugia malayi ecdysone receptor 0.0031 0.0024 0.0201
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0017 0.0604
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0313 0.055 1
Echinococcus granulosus caspase 0.0369 0.0654 0.0804
Schistosoma mansoni aldo-keto reductase 0.0313 0.055 0.0676
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0091 0.0136 0.2326
Entamoeba histolytica hypothetical protein 0.0065 0.0088 0.0996
Entamoeba histolytica hypothetical protein 0.0161 0.0267 0.3263
Onchocerca volvulus 0.0313 0.055 0.4571
Schistosoma mansoni heat shock protein 0.0034 0.003 0.0037
Echinococcus multilocularis heat shock protein 90 0.0027 0.0017 0.0017
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0037 0.0036 0.0142
Schistosoma mansoni coup transcription factor 0.0065 0.0089 0.0109
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0127 0.0204 0.025
Loa Loa (eye worm) hypothetical protein 0.0065 0.0088 0.0723
Schistosoma mansoni patched 1 0.0192 0.0323 0.0398
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0065 0.0089 0.0109
Echinococcus multilocularis transcription factor btf3 0.0072 0.01 0.01
Brugia malayi intermediate filament protein 0.0028 0.002 0.0163
Trichomonas vaginalis heat shock protein, putative 0.0034 0.003 0.0554
Loa Loa (eye worm) oxidoreductase 0.0313 0.055 0.4594
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.014 0.0227 0.4015
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0037 0.0036 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0227 0.4124
Loa Loa (eye worm) oxidoreductase 0.0037 0.0036 0.0279
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0163 0.297
Brugia malayi Muscleblind-like protein 0.0479 0.0859 0.719
Brugia malayi nuclear hormone receptor 0.0065 0.0089 0.074
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0313 0.055 0.0676
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Onchocerca volvulus 0.0027 0.0017 0.0083
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0065 0.0088 0.1453
Echinococcus granulosus microtubule associated protein 2 0.4385 0.8135 1
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0017 0.0318
Loa Loa (eye worm) hypothetical protein 0.0034 0.003 0.0234
Giardia lamblia Aldose reductase 0.0313 0.055 1
Echinococcus granulosus aldo keto reductase 0.0313 0.055 0.0676
Schistosoma mansoni survival motor neuron protein 0.0048 0.0056 0.0069
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0313 0.055 1
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0014 0.0262
Entamoeba histolytica protein kinase domain containing protein 0.0297 0.052 0.6474
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0091 0.0136 0.0167
Loa Loa (eye worm) hypothetical protein 0.0035 0.0031 0.0242
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0227 0.4124
Loa Loa (eye worm) hypothetical protein 0.0035 0.0031 0.0242
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0061 0.008 0.0099
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.014 0.0227 0.1897
Entamoeba histolytica aldose reductase, putative 0.0313 0.055 0.6852
Schistosoma mansoni lamin 0.0028 0.002 0.0024
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0115 0.0181 0.1498
Loa Loa (eye worm) oxidoreductase 0.0313 0.055 0.4594
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0037 0.0036 0.0255
Echinococcus multilocularis FTZ F1 alpha 0.0065 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0032 0.0026 0.0195
Echinococcus granulosus transcription factor btf3 0.0072 0.01 0.0123
Trypanosoma brucei aldo-keto reductase, putative 0.0313 0.055 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0088 0.0723
Leishmania major basic transcription factor 3a, putative 0.0072 0.01 0.1669
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0094 0.0142 1
Trypanosoma brucei Metacaspase-4 0.014 0.0227 0.4015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Echinococcus granulosus replication factor c subunit 1 0.0065 0.0088 0.0109
Entamoeba histolytica acyl-CoA synthetase, putative 0.0126 0.0201 0.2428
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0163 0.297
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0074 0.1349
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0065 0.0089 0.074
Leishmania major 4-coumarate:coa ligase-like protein 0.0126 0.0201 0.3543
Loa Loa (eye worm) inositol-1 0.0041 0.0043 0.0339
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Brugia malayi Pip kinase protein 2 0.0172 0.0286 0.2395
Echinococcus multilocularis nibrin 0.0065 0.0088 0.0088
Schistosoma mansoni potassium channel beta 0.0091 0.0136 0.0167
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0166 0.0275 0.3369
Trypanosoma cruzi metacaspase, putative 0.014 0.0227 0.4077
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0161 0.0267 0.0267
Echinococcus multilocularis muscleblind protein 0.0479 0.0859 0.0859
Loa Loa (eye worm) patched family protein 0.0027 0.0017 0.0124
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0337 0.0595 0.4973
Mycobacterium ulcerans acyl-CoA synthetase 0.0126 0.0201 0.0801
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0313 0.055 0.0676
Schistosoma mansoni DNA ligase IV 0.0065 0.0088 0.0109
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Loa Loa (eye worm) MH2 domain-containing protein 0.0252 0.0436 0.3635
Brugia malayi ecdysteroid receptor 0.0065 0.0089 0.074
Schistosoma mansoni endoplasmin 0.0034 0.003 0.0037
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0112 0.1884
Onchocerca volvulus 0.0313 0.055 0.4571
Brugia malayi hypothetical protein 0.0065 0.0088 0.0739
Brugia malayi Protein kinase domain containing protein 0.0297 0.052 0.4354
Schistosoma mansoni steroid hormone receptor ad4bp 0.0065 0.0089 0.0109
Trypanosoma brucei metacaspase 0.014 0.0227 0.4015
Trypanosoma brucei metacaspase MCA3 0.014 0.0227 0.4015
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0126 0.0201 0.1443
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0184
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0184
Trichomonas vaginalis aldo-keto reductase, putative 0.0313 0.055 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0227 0.4124
Leishmania major 4-coumarate:coa ligase-like protein 0.0126 0.0201 0.3543
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.003 0.0251
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0043 0.3824
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0036 0.0473
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0724
Trypanosoma cruzi heat shock protein 90, putative 0.0034 0.003 0.0479
Echinococcus granulosus heat shock protein 90 0.0027 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Trypanosoma cruzi transcription factor btf3, putative 0.0072 0.01 0.1756
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0313 0.055 0.055
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0014 0.0262
Treponema pallidum heat shock protein 90 0.0027 0.0017 0.0634
Onchocerca volvulus 0.0313 0.055 0.4571
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0126 0.0201 0.0801
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0037 0.0036 0.0142
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0042 0.0596
Trypanosoma cruzi polo-like protein kinase, putative 0.0106 0.0163 0.2914
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0062 0.0443
Brugia malayi Calcitonin receptor-like protein seb-1 0.0108 0.0167 0.14
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0024 0.0201
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0065 0.0089 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0088 0.1609
Brugia malayi hypothetical protein 0.013 0.0209 0.1748
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Echinococcus granulosus lamin dm0 0.0028 0.002 0.0024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0227 0.4124
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0724
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0166 0.0275 0.5009
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0036 0.0142
Schistosoma mansoni transcription factor btf3 0.0072 0.01 0.0123
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0037 0.0036 0.0142
Echinococcus multilocularis caspase 3 0.023 0.0394 0.0394
Loa Loa (eye worm) hypothetical protein 0.0192 0.0323 0.2694
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0074 0.1349
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0313 0.055 0.0676
Onchocerca volvulus 0.0031 0.0024 0.0142
Giardia lamblia Aldose reductase 0.0313 0.055 1
Schistosoma mansoni intermediate filament proteins 0.0028 0.002 0.0024
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0313 0.055 1
Echinococcus multilocularis aldo keto reductase 0.0313 0.055 0.055
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0024 0.0024
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.003 0.0479
Loa Loa (eye worm) hypothetical protein 0.0078 0.0112 0.0918
Entamoeba histolytica aldose reductase, putative 0.0313 0.055 0.6852
Plasmodium vivax basic transcription factor 3b, putative 0.0072 0.01 0.4231
Leishmania major prostaglandin f synthase, putative 0.0313 0.055 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0166 0.0275 0.5009
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0065 0.0088 0.1609
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0037 0.0036 0.0142
Schistosoma mansoni rab6-interacting 0.0022 0.0007 0.0009
Toxoplasma gondii NAC domain-containing protein 0.0072 0.01 0.1669
Brugia malayi CHE-14 protein 0.0192 0.0323 0.2706
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0767 0.1395 1
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0031 0.0259
Trypanosoma cruzi aldo/keto reductase, putative 0.0313 0.055 1
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0036 0.0573
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0019 0.0515
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0127 0.0204 0.081
Onchocerca volvulus 0.0028 0.002 0.0104
Trypanosoma brucei protein kinase, putative 0.0058 0.0074 0.1189
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0313 0.055 0.055
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.0386 0.0685 0.2727
Trypanosoma cruzi transcription factor btf3, putative 0.0072 0.01 0.1756
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.002 0.0145
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0058 0.0074 0.1281
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0058 0.0074 0.1189
Loa Loa (eye worm) patched family protein 0.0027 0.0017 0.0124
Loa Loa (eye worm) hypothetical protein 0.0065 0.0088 0.0723
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0065 0.0089 0.0724
Plasmodium vivax aldehyde reductase, putative 0.0091 0.0136 0.5847
Entamoeba histolytica transcription factor BTF3, putative 0.0072 0.01 0.1144
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0724
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0065 0.0089 0.074
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0184
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Loa Loa (eye worm) hypothetical protein 0.0446 0.0798 0.6674
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0227 0.4124
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0184
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0065 0.0089 0.0089
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0007 0.0007
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0227 0.4124
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0065 0.0089 0.0109
Loa Loa (eye worm) hypothetical protein 0.0295 0.0516 0.4307
Echinococcus granulosus nuclear receptor nhr 48 0.0031 0.0024 0.003
Trypanosoma brucei heat shock protein, putative 0.0034 0.003 0.0379
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.014 0.0227 0.4015
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0227 0.4124
Mycobacterium tuberculosis Probable oxidoreductase 0.0313 0.055 0.2188
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0043 0.0777
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.0036 0.0573
Trichomonas vaginalis aldo-keto reductase, putative 0.0313 0.055 1
Brugia malayi protein C24B5.3 0.0027 0.0017 0.0142
Trypanosoma brucei heat shock protein, putative 0.0034 0.003 0.0379
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0036 0.0296
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0037 0.0036 0.0473
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Brugia malayi Pax transcription activation domain interacting protein 0.0065 0.0088 0.0739
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0031 0.0024 0.0201
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.003 0.0379
Loa Loa (eye worm) hypothetical protein 0.014 0.0227 0.1883
Schistosoma mansoni hypothetical protein 0.1069 0.1959 0.2408
Toxoplasma gondii heat shock protein 90, putative 0.0034 0.003 0.0379
Schistosoma mansoni tar DNA-binding protein 0.0206 0.0351 0.0431
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0065 0.0089 0.0724
Echinococcus multilocularis aldo keto reductase 0.0313 0.055 0.055
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0297 0.052 0.4344
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.003 0.0259
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Schistosoma mansoni lamin 0.0028 0.002 0.0024
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0313 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.027 0.0469 0.3915
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0024 0.0024
Brugia malayi nuclear receptor RXR 0.0031 0.0024 0.0201
Brugia malayi MH2 domain containing protein 0.0252 0.0436 0.3646
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0078 0.0112 0.4759
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.01 0.1821
Brugia malayi Patched family protein 0.0027 0.0017 0.0142
Onchocerca volvulus 0.0027 0.0017 0.0083
Loa Loa (eye worm) hypothetical protein 0.0126 0.0201 0.167
Trypanosoma brucei metacaspase 5, putative 0.014 0.0227 0.4015
Echinococcus multilocularis neuropeptide s receptor 0.0466 0.0835 0.0835
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.0036 0.0255
Trypanosoma cruzi metacaspase 5, putative 0.014 0.0227 0.4077
Brugia malayi steroid hormone receptor 0.0065 0.0089 0.074
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0127 0.0204 0.0204
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0313 0.055 0.0676
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0313 0.055 0.3942
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0126 0.0201 0.0801
Schistosoma mansoni hypothetical protein 0.0034 0.003 0.0037
Giardia lamblia Heat shock protein HSP 90-alpha 0.0027 0.0017 0.0138
Trichomonas vaginalis aldo-keto reductase, putative 0.0313 0.055 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0035 0.0249
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0089 0.0132 0.0527
Brugia malayi topoisomerase 0.0065 0.0088 0.0739
Echinococcus multilocularis replication factor c subunit 1 0.0065 0.0088 0.0088
Trypanosoma cruzi heat shock protein 85, putative 0.0027 0.0017 0.0241
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0313 0.055 0.0676
Trichomonas vaginalis endoplasmin, putative 0.0021 0.0006 0.0105
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0024 0.003
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.0036 0.0279
Brugia malayi RNA, U transporter 1 0.009 0.0134 0.1121
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.002 0.0163
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0019 0.0261
Toxoplasma gondii patched family protein 0.0027 0.0017 0.0131
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0065 0.0089 0.074
Entamoeba histolytica acyl-CoA synthetase, putative 0.0126 0.0201 0.2428
Echinococcus multilocularis ecdysone induced protein 78C 0.0065 0.0089 0.0089
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0027 0.0017 0.0125
Echinococcus granulosus mitogen activated protein kinase 0.0058 0.0074 0.0091
Echinococcus granulosus expressed conserved protein 0.0419 0.0748 0.0919
Giardia lamblia Replication factor C, subunit 1 0.0065 0.0088 0.1454
Onchocerca volvulus 0.0313 0.055 0.4571
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0313 0.055 0.4603
Brugia malayi Probable ClpP-like protease 0.0078 0.0112 0.0934
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0058 0.0074 0.1189
Trypanosoma brucei heat shock protein, putative 0.0034 0.003 0.0379
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0052 0.0063
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0037 0.0036 0.0142
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0042 0.0052
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0091 0.0136 0.2326
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0058 0.0074 0.1281
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0136 0.2466
Loa Loa (eye worm) patched family protein 0.0027 0.0017 0.0124
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0124
Entamoeba histolytica hypothetical protein 0.0297 0.052 0.6474
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0112 0.0445
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0024 0.003
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0036 0.0142
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0166 0.0275 0.5009
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0065 0.0089 0.074
Trichomonas vaginalis ran, putative 0.0023 0.001 0.0182
Entamoeba histolytica protein kinase, putative 0.0297 0.052 0.6474
Brugia malayi orphan nuclear receptor NR2E1 0.0031 0.0024 0.0201
Loa Loa (eye worm) transcription factor SMAD2 0.0252 0.0436 0.3635
Echinococcus multilocularis microtubule associated protein 2 0.4385 0.8135 0.8135
Trichomonas vaginalis aldo-keto reductase, putative 0.0313 0.055 1
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0027 0.0017 0.0069
Echinococcus multilocularis caspase 0.0369 0.0654 0.0654
Schistosoma mansoni transcription factor LCR-F1 0.0161 0.0267 0.0328
Brugia malayi hypothetical protein 0.0035 0.0031 0.0259
Echinococcus granulosus voltage gated potassium channel subunit 0.0091 0.0136 0.0167
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.0036 0.0279
Echinococcus granulosus tumor protein p63 0.1439 0.2648 0.3255
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0024 0.003
Brugia malayi photoreceptor-specific nuclear receptor 0.0065 0.0089 0.074
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0027 0.0017 0.0138
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0061 0.008 0.008
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Brugia malayi hypothetical protein 0.0031 0.0024 0.0201
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.0036 0.0647
Echinococcus granulosus ecdysone induced protein 78C 0.0065 0.0089 0.0109
Schistosoma mansoni loxhd1 0.0022 0.0007 0.0009
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0246 0.0426 0.3551
Schistosoma mansoni ran 0.0023 0.001 0.0012
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0227 0.4124
Echinococcus granulosus caspase 8 0.014 0.0227 0.0279
Schistosoma mansoni RAR-like nuclear receptor 0.0065 0.0089 0.0109
Echinococcus multilocularis expressed conserved protein 0.0419 0.0748 0.0748
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0019 0.0159
Plasmodium vivax hypothetical protein, conserved 0.014 0.0227 1
Leishmania major heat shock protein 83-1 0.0034 0.003 0.0379
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0007 0.0042
Trichomonas vaginalis aldo-keto reductase, putative 0.0313 0.055 1
Loa Loa (eye worm) hypothetical protein 0.0235 0.0405 0.3381
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0297 0.052 0.9449
Trypanosoma brucei heat shock protein, putative 0.0034 0.003 0.0379
Echinococcus granulosus mitogen activated protein kinase 3 0.0058 0.0074 0.0091
Toxoplasma gondii patched family protein 0.0027 0.0017 0.0131
Brugia malayi Endoplasmin precursor 0.0034 0.003 0.0253
Entamoeba histolytica acyl-coA synthetase, putative 0.0126 0.0201 0.2428
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0192 0.0323 0.2694
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0032 0.0026 0.0103
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.003 0.0479
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0042 0.0767

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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