Detailed information for compound 619056

Basic information

Technical information
  • TDR Targets ID: 619056
  • Name: N-(2-tert-butyl-4,6-dihydrothieno[3,4-d]pyraz ol-3-yl)-4-chlorobenzamide
  • MW: 335.852 | Formula: C16H18ClN3OS
  • H donors: 1 H acceptors: 2 LogP: 2.98 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)C(=O)Nc1c2CSCc2nn1C(C)(C)C
  • InChi: 1S/C16H18ClN3OS/c1-16(2,3)20-14(12-8-22-9-13(12)19-20)18-15(21)10-4-6-11(17)7-5-10/h4-7H,8-9H2,1-3H3,(H,18,21)
  • InChiKey: YBQVWZZIOMMGPE-UHFFFAOYSA-N  

Network

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Synonyms

  • N-(2-tert-butyl-4,6-dihydrothieno[3,4-d]pyrazol-3-yl)-4-chloro-benzamide
  • ZINC00189424
  • Oprea1_877581
  • IDI1_020534
  • ChemDiv3_001568

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0121 0.0101 0.0277
Echinococcus granulosus alpha 1A adrenergic receptor 0.0048 0.0019 0.0019
Brugia malayi hypothetical protein 0.0048 0.0019 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0005 0.0005
Onchocerca volvulus 0.0049 0.002 0.0423
Trypanosoma cruzi cyclin 6, putative 0.004 0.001 0.0017
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0121 0.0101 1
Plasmodium vivax ataxin-2 like protein, putative 0.0079 0.0053 0.5102
Onchocerca volvulus 0.0048 0.0019 0.0398
Leishmania major hypothetical protein, conserved 0.0079 0.0053 0.0136
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.001 0.0086
Toxoplasma gondii exonuclease III APE 0.0077 0.0051 0.0709
Schistosoma mansoni ap endonuclease 0.0077 0.0051 0.0771
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0048 0.0019 0.0284
Trypanosoma cruzi DNA polymerase eta, putative 0.004 0.001 0.0016
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0121 0.0101 0.1511
Trichomonas vaginalis PIKK family atypical protein kinase 0.0356 0.036 0.5386
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0121 0.0101 0.1454
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0234 0.0226 0.0638
Echinococcus granulosus hypothetical protein 0.0048 0.0019 0.0019
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0099 0.0076 0.1146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0226 0.3351
Loa Loa (eye worm) hypothetical protein 0.0371 0.0377 0.5668
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Schistosoma mansoni neuropeptide F-like receptor 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Onchocerca volvulus 0.0048 0.0019 0.0398
Brugia malayi G-protein coupled receptor 0.0048 0.0019 0.0284
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0121 0.0101 0.1511
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.001 0.0152
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Trichomonas vaginalis cyclin A, putative 0.004 0.001 0.009
Schistosoma mansoni biogenic amine (5HT) receptor 0.0048 0.0019 0.0284
Giardia lamblia Heat shock protein HSP 90-alpha 0.0085 0.006 0.0758
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Trypanosoma cruzi heat shock protein 85, putative 0.0085 0.006 0.0159
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Schistosoma mansoni neuropeptide receptor 0.0048 0.0019 0.0284
Mycobacterium tuberculosis Conserved protein 0.0076 0.005 0.0809
Entamoeba histolytica hypothetical protein 0.0356 0.036 0.5386
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0046 0.0046
Echinococcus granulosus neuropeptide receptor A26 0.0048 0.0019 0.0019
Echinococcus granulosus allatostatin A receptor 0.0048 0.0019 0.0019
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0051 0.4874
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0076 0.005 0.0809
Onchocerca volvulus 0.0048 0.0019 0.0398
Loa Loa (eye worm) hypothetical protein 0.0275 0.0271 0.4072
Leishmania major cyclin 0.004 0.001 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Giardia lamblia G2/mitotic-specific cyclin B 0.004 0.001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0459 0.0474 0.7133
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0046 0.0046
Trypanosoma brucei mitotic cyclin 6 0.004 0.001 0.009
Brugia malayi Dopamine receptor 0.0048 0.0019 0.0284
Echinococcus multilocularis dna polymerase eta 0.004 0.001 0.001
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0121 0.0101 0.0101
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.001 0.0016
Echinococcus multilocularis GPCR, family 2 0.0031 0.0000073185 0.0000073185
Trypanosoma cruzi heat shock protein 90, putative 0.0067 0.0041 0.0104
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0121 0.0101 0.0277
Schistosoma mansoni endoplasmin 0.0085 0.006 0.0899
Onchocerca volvulus 0.0048 0.0019 0.0398
Leishmania major hypothetical protein, unknown function 0.0121 0.0101 0.0266
Toxoplasma gondii LsmAD domain-containing protein 0.0079 0.0053 0.0742
Brugia malayi RNA, U transporter 1 0.0086 0.0061 0.0922
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0121 0.0101 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Onchocerca volvulus 0.0048 0.0019 0.0398
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0121 0.0101 0.1454
Echinococcus multilocularis serotonin receptor 0.0048 0.0019 0.0019
Entamoeba histolytica hypothetical protein 0.0121 0.0101 0.1454
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.005 0.0688
Echinococcus multilocularis 0.0121 0.0101 0.0101
Echinococcus multilocularis serotonin receptor 0.0048 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Schistosoma mansoni cyclins 0.004 0.001 0.0157
Trichomonas vaginalis cyclin B, putative 0.004 0.001 0.009
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0121 0.0101 0.1454
Loa Loa (eye worm) endoplasmin 0.0085 0.006 0.0899
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0121 0.0101 0.1454
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0631 0.0665 0.1903
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0631 0.0665 0.1832
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0121 0.0101 0.0277
Schistosoma mansoni hypothetical protein 0.0031 0.0000073185 0.0001
Echinococcus multilocularis neuropeptide receptor 0.0048 0.0019 0.0019
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.001 0.0086
Leishmania major phosphatidylinositol 3-kinase, putative 0.0631 0.0665 0.1832
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0019 0.0284
Echinococcus multilocularis dro:myosuppressin receptor 0.0048 0.0019 0.0019
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0048 0.0019 0.0019
Mycobacterium leprae conserved hypothetical protein 0.0121 0.0101 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Echinococcus multilocularis cyclins 0.004 0.001 0.001
Echinococcus multilocularis snurportin 1 0.0323 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0396 0.0405 0.6094
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0048 0.0019 0.0019
Echinococcus granulosus G2:mitotic specific cyclin B3 0.004 0.001 0.001
Echinococcus granulosus cyclin b3 0.004 0.001 0.001
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Loa Loa (eye worm) hypothetical protein 0.0459 0.0474 0.7133
Trypanosoma brucei PAB1-binding protein , putative 0.0079 0.0053 0.0742
Entamoeba histolytica protein kinase rad3, putative 0.0356 0.036 0.5386
Loa Loa (eye worm) G-protein coupled receptor 0.0048 0.0019 0.0284
Toxoplasma gondii ABC1 family protein 0.0076 0.005 0.0688
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0019 0.0284
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0121 0.0101 0.1454
Echinococcus granulosus tm gpcr rhodopsin 0.0048 0.0019 0.0019
Echinococcus granulosus heat shock protein 0.0085 0.006 0.006
Loa Loa (eye worm) phosphatidylinositol 3 0.0121 0.0101 0.1511
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0121 0.0101 0.1454
Brugia malayi AKH receptor 0.0048 0.0019 0.0284
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0121 0.0101 0.1454
Loa Loa (eye worm) heat shock protein 90 0.0085 0.006 0.0899
Brugia malayi Serotonin receptor 0.0048 0.0019 0.0284
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0121 0.0101 0.1511
Schistosoma mansoni fkbp-rapamycin associated protein 0.0356 0.036 0.5417
Trichomonas vaginalis PIKK family atypical protein kinase 0.0356 0.036 0.5386
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0631 0.0665 1
Schistosoma mansoni opsin-like receptor 0.0048 0.0019 0.0284
Echinococcus multilocularis neuropeptide receptor 0.0048 0.0019 0.0019
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0631 0.0665 0.0665
Trichomonas vaginalis conserved hypothetical protein 0.0234 0.0226 0.3351
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0121 0.0101 0.1454
Echinococcus granulosus survival motor neuron protein 1 0.0487 0.0506 0.0506
Echinococcus multilocularis allatostatin A receptor 0.0048 0.0019 0.0019
Leishmania major DNA polymerase kappa, putative 0.004 0.001 0.0016
Echinococcus granulosus 7TM GPCR rhodopsin 0.0048 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Schistosoma mansoni hypothetical protein 0.0048 0.0019 0.0284
Echinococcus granulosus neuropeptide receptor 0.0048 0.0019 0.0019
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0048 0.0019 0.0019
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.0121 0.1822
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0000073185 0.0000073185
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0121 0.0121
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0048 0.0019 0.0019
Entamoeba histolytica hypothetical protein 0.0072 0.0046 0.0629
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0019 0.0284
Brugia malayi G protein-coupled receptor 0.0048 0.0019 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0121 0.0101 0.1454
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Echinococcus granulosus G protein coupled receptor 139 0.0048 0.0019 0.0019
Mycobacterium ulcerans lipase LipD 0.0076 0.005 0.9659
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.0066 0.004 0.0595
Trypanosoma brucei heat shock protein, putative 0.0085 0.006 0.0838
Trypanosoma cruzi CYC2-like cyclin, putative 0.004 0.001 0.0017
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.001 0.0016
Schistosoma mansoni hypothetical protein 0.0066 0.004 0.0595
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.005 0.0131
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0005 0.0005
Brugia malayi beta-lactamase family protein 0.0076 0.005 0.075
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.001 0.0016
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0000073185 0.0000073185
Trypanosoma cruzi hypothetical protein, conserved 0.3167 0.3475 1
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.001 0.0086
Echinococcus granulosus neuropeptide receptor 0.0048 0.0019 0.0019
Trypanosoma brucei heat shock protein, putative 0.0085 0.006 0.0838
Echinococcus granulosus g protein coupled receptor 0.0048 0.0019 0.0019
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0000073185 0.0001
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0048 0.0019 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Onchocerca volvulus 0.0048 0.0019 0.0398
Echinococcus granulosus cyclin B3 1 0.004 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0099 0.0076 0.1146
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0631 0.0665 1
Trypanosoma brucei heat shock protein, putative 0.0085 0.006 0.0838
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0631 0.0665 1
Onchocerca volvulus 0.0121 0.0101 0.2119
Echinococcus multilocularis fmrfamide receptor 0.0048 0.0019 0.0019
Giardia lamblia Cyclin A 0.004 0.001 0.0005
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0048 0.0019 0.0284
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0000073185 0.0001
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0631 0.0665 1
Trypanosoma brucei heat shock protein, putative 0.0085 0.006 0.0838
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0121 0.0101 0.1454
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0356 0.036 0.036
Entamoeba histolytica cyclin family protein 0.004 0.001 0.009
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.005 0.0688
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0121 0.0101 0.1511
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0121 0.0121
Entamoeba histolytica hypothetical protein 0.0121 0.0101 0.1454
Entamoeba histolytica cyclin, putative 0.004 0.001 0.009
Onchocerca volvulus Huntingtin homolog 0.0371 0.0377 0.7946
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0121 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Echinococcus granulosus neuropeptides capa receptor 0.0048 0.0019 0.0019
Schistosoma mansoni survival motor neuron protein 0.0099 0.0076 0.1146
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0631 0.0665 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0005 0.0005
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.002 0.0302
Echinococcus granulosus neuropeptide FF receptor 2 0.0048 0.0019 0.0019
Trypanosoma brucei heat shock protein, putative 0.0085 0.006 0.0838
Plasmodium vivax heat shock protein 86, putative 0.0085 0.006 0.5759
Trichomonas vaginalis PIKK family atypical protein kinase 0.0356 0.036 0.5386
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.001 0.0086
Schistosoma mansoni growth hormone secretagogue receptor 0.0048 0.0019 0.0284
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0121 0.0101 0.1454
Loa Loa (eye worm) phosphatidylinositol 3 0.0121 0.0101 0.1511
Brugia malayi hypothetical protein 0.0371 0.0377 0.5668
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.001 0.0086
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0048 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0487 0.0506 0.761
Mycobacterium tuberculosis Conserved hypothetical protein 0.0121 0.0101 0.184
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0077 0.0051 0.0838
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Echinococcus granulosus somatostatin receptor 0.0048 0.0019 0.0019
Entamoeba histolytica hypothetical protein 0.0121 0.0101 0.1454
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0019 0.0284
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0048 0.0019 0.0398
Schistosoma mansoni lozenge 0.0058 0.003 0.0448
Brugia malayi Dopamine receptor protein 1 0.0048 0.0019 0.0284
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0121 0.0101 0.0277
Echinococcus multilocularis tumor protein p63 0.0333 0.0335 0.0335
Loa Loa (eye worm) melatonin receptor type 1A 0.0048 0.0019 0.0284
Schistosoma mansoni heat shock protein 0.0035 0.0004 0.0067
Brugia malayi Bromodomain containing protein 0.0074 0.0048 0.0715
Echinococcus multilocularis cyclins 0.004 0.001 0.001
Echinococcus granulosus dna polymerase eta 0.004 0.001 0.001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0121 0.0101 0.1511
Plasmodium falciparum endoplasmin, putative 0.0052 0.0024 0.1987
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0077 0.0051 0.0051
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0121 0.0101 0.1511
Echinococcus multilocularis cyclins 0.004 0.001 0.001
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Trypanosoma cruzi Heat shock protein 83, putative 0.0085 0.006 0.0159
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0121 0.0101 0.0266
Trypanosoma brucei heat shock protein 90, putative 0.0085 0.006 0.0838
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0077 0.0051 0.0629
Echinococcus granulosus endoplasmin 0.0067 0.0041 0.0041
Schistosoma mansoni cyclin B 0.004 0.001 0.0157
Leishmania major hypothetical protein, conserved 0.3289 0.361 1
Brugia malayi heat shock protein 90 0.0085 0.006 0.0899
Trypanosoma brucei heat shock protein, putative 0.0085 0.006 0.0838
Schistosoma mansoni biogenic amine receptor 0.0048 0.0019 0.0284
Echinococcus multilocularis Zinc finger, PHD finger 0.0121 0.0101 0.0101
Echinococcus granulosus neuropeptide s receptor 0.0048 0.0019 0.0019
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0046 0.0692
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0121 0.0101 0.1454
Echinococcus multilocularis survival motor neuron protein 1 0.0487 0.0506 0.0506
Brugia malayi Hsp90 protein 0.0035 0.0004 0.0067
Echinococcus multilocularis somatostatin receptor 0.0048 0.0019 0.0019
Schistosoma mansoni amine GPCR 0.0048 0.0019 0.0284
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0121 0.0101 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Echinococcus granulosus dro:myosuppressin receptor 0.0048 0.0019 0.0019
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 0.0019 0.0284
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0121 0.0101 0.1511
Brugia malayi hypothetical protein 0.0051 0.0022 0.0338
Brugia malayi G protein-coupled receptor F59B2.13 0.0048 0.0019 0.0284
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0121 0.0101 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Mycobacterium leprae conserved hypothetical protein 0.0076 0.005 0.1535
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0053 0.0141
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0631 0.0665 0.1832
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0121 0.0101 0.0101
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0121 0.0101 0.1454
Echinococcus granulosus serotonin receptor 0.0048 0.0019 0.0019
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0356 0.036 0.5417
Trichomonas vaginalis cyclins, putative 0.004 0.001 0.009
Brugia malayi hypothetical protein 0.0079 0.0053 0.0804
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0121 0.0101 0.1454
Leishmania major DNA polymerase eta, putative 0.004 0.001 0.0016
Trichomonas vaginalis esterase, putative 0.0076 0.005 0.0688
Loa Loa (eye worm) hypothetical protein 0.0049 0.002 0.0302
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0356 0.036 0.5417
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0048 0.0019 0.0019
Treponema pallidum exodeoxyribonuclease (exoA) 0.0077 0.0051 1
Schistosoma mansoni bromodomain containing protein 0.0062 0.0035 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0121 0.0101 0.0101
Echinococcus granulosus g-protein coupled receptor 0.0048 0.0019 0.0019
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0076 0.005 0.9659
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0121 0.0101 0.0277
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.001 0.0152
Entamoeba histolytica hypothetical protein 0.0072 0.0046 0.0629
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Plasmodium vivax hypothetical protein, conserved 0.0121 0.0101 1
Loa Loa (eye worm) hypothetical protein 0.0234 0.0226 0.3395
Mycobacterium ulcerans esterase/lipase LipP 0.0076 0.005 0.9659
Trichomonas vaginalis cyclins, putative 0.004 0.001 0.009
Schistosoma mansoni hypothetical protein 0.0164 0.0147 0.2217
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0121 0.0101 1
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.001 0.0086
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.001 0.0152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0048 0.0019 0.0284
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0000073185 0.0001
Echinococcus granulosus tm gpcr rhodopsin 0.0048 0.0019 0.0019
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0077 0.0051 0.0135
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Echinococcus granulosus cyclins 0.004 0.001 0.001
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0048 0.0019 0.0284
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0323 0.0324 0.4867
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0356 0.036 0.5386
Loa Loa (eye worm) hypothetical protein 0.0076 0.005 0.075
Loa Loa (eye worm) hypothetical protein 0.004 0.001 0.0157
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0121 0.0101 0.1454
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0121 0.0101 0.1454
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0631 0.0665 0.0665
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0356 0.036 0.036
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.001 0.0152
Trypanosoma cruzi cyclin, putative 0.004 0.001 0.0017
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0631 0.0665 1
Echinococcus granulosus snurportin 1 0.0323 0.0324 0.0324
Schistosoma mansoni hypothetical protein 0.0164 0.0147 0.2217
Loa Loa (eye worm) hypothetical protein 0.0121 0.0101 0.1511
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0121 0.0101 0.1511
Echinococcus multilocularis neuropeptide Y receptor 0.0048 0.0019 0.0019
Entamoeba histolytica heat shock protein 90, putative 0.0085 0.006 0.0838
Brugia malayi hypothetical protein 0.0048 0.0019 0.0284
Onchocerca volvulus 0.0048 0.0019 0.0398
Trichomonas vaginalis PIKK family atypical protein kinase 0.0356 0.036 0.5386
Echinococcus granulosus GPCR family 2 0.0031 0.0000073185 0.0000073185
Schistosoma mansoni amine GPCR 0.0048 0.0019 0.0284
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0048 0.0019 0.0284
Schistosoma mansoni hypothetical protein 0.0072 0.0046 0.0692
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0048 0.0019 0.0019
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0048 0.0019 0.0284
Brugia malayi G-protein coupled receptor 0.0048 0.0019 0.0284
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0121 0.0101 0.1511
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.004 0.001 0.0157
Echinococcus granulosus biogenic amine 5HT receptor 0.0048 0.0019 0.0019
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0077 0.0051 0.0709
Onchocerca volvulus 0.0048 0.0019 0.0398
Echinococcus granulosus cyclins 0.004 0.001 0.001
Schistosoma mansoni histamine h1 receptor 0.0048 0.0019 0.0284
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0121 0.0101 0.1511
Onchocerca volvulus Huntingtin homolog 0.0371 0.0377 0.7946
Brugia malayi Calcitonin receptor-like protein seb-1 0.0097 0.0074 0.1107
Giardia lamblia GTOR 0.0631 0.0665 1
Trichomonas vaginalis cyclin B, putative 0.004 0.001 0.009
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.001 0.0086
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Trichomonas vaginalis heat shock protein, putative 0.0085 0.006 0.0838
Schistosoma mansoni biogenic amine receptor 0.0048 0.0019 0.0284
Echinococcus multilocularis beta LACTamase domain containing family member 0.0076 0.005 0.005
Trichomonas vaginalis cyclin B3, putative 0.004 0.001 0.009
Entamoeba histolytica cyclin family protein 0.004 0.001 0.009
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0048 0.0019 0.0019
Brugia malayi hypothetical protein 0.0072 0.0046 0.0692
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0076 0.005 0.0809
Echinococcus multilocularis cyclin B3 1 0.004 0.001 0.001
Schistosoma mansoni cyclin B3 0.004 0.001 0.0157
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0121 0.1822
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0048 0.0019 0.0284
Echinococcus multilocularis Protein lozenge 0.0058 0.003 0.003
Echinococcus multilocularis neuropeptides capa receptor 0.0048 0.0019 0.0019
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0048 0.0019 0.0019
Schistosoma mansoni opsin-like receptor 0.0048 0.0019 0.0284
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0031 0.0031
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Trichomonas vaginalis PIKK family atypical protein kinase 0.0121 0.0101 0.1454
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0048 0.0019 0.0284
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0356 0.036 0.5386
Brugia malayi Bromodomain containing protein 0.0038 0.0008 0.0115
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0051 0.0709
Loa Loa (eye worm) hypothetical protein 0.0031 0.0000073185 0.0001
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0048 0.0019 0.0284
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.005 0.0688
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0483 0.0502 1
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Brugia malayi hypothetical protein 0.0048 0.0019 0.0284
Trypanosoma cruzi heat shock protein 85, putative 0.0067 0.0041 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Echinococcus granulosus g protein coupled receptor 0.0048 0.0019 0.0019
Mycobacterium ulcerans hypothetical protein 0.0076 0.005 0.9659
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0356 0.036 0.1025
Schistosoma mansoni myosin xvIII 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.0042 0.0012 0.0186
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0076 0.005 0.075
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Brugia malayi hypothetical protein 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Schistosoma mansoni hypothetical protein 0.0048 0.0019 0.0284
Trichomonas vaginalis heat shock protein, putative 0.0067 0.0041 0.0549
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0048 0.0019 0.0284
Echinococcus multilocularis cyclin B 0.004 0.001 0.001
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0000073185 0.0000073185
Loa Loa (eye worm) hypothetical protein 0.0079 0.0053 0.0804
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.004 0.001 0.001
Echinococcus multilocularis dna polymerase kappa 0.004 0.001 0.001
Brugia malayi latrophilin 2 splice variant baaae 0.0066 0.004 0.0595
Echinococcus multilocularis g protein coupled receptor 0.0048 0.0019 0.0019
Trichomonas vaginalis heat shock protein, putative 0.0067 0.0041 0.0549
Echinococcus granulosus sex peptide receptor 0.0048 0.0019 0.0019
Echinococcus granulosus neuropeptides capa receptor 0.0048 0.0019 0.0019
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0121 0.0101 0.1454
Trichomonas vaginalis cyclin B, putative 0.004 0.001 0.009
Loa Loa (eye worm) hypothetical protein 0.0121 0.0101 0.1511
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Brugia malayi RE15519p 0.0048 0.0019 0.0284
Giardia lamblia Phosphatidylinositol 4-kinase 0.0121 0.0101 0.1381
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0631 0.0665 0.0665
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Leishmania major phosphatidylinositol kinase related protein, putative 0.0121 0.0101 0.0266
Trypanosoma cruzi target of rapamycin kinase 3 0.0631 0.0665 0.1903
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0121 0.0101 0.1454
Plasmodium falciparum cyclin 0.004 0.001 0.0622
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0631 0.0665 0.0665
Echinococcus granulosus cyclins 0.004 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0356 0.036 0.5386
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0077 0.0051 0.0771
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Echinococcus multilocularis serine protein kinase ATM 0.0356 0.036 0.036
Echinococcus granulosus neuropeptide Y receptor 0.0048 0.0019 0.0019
Echinococcus multilocularis cyclins 0.004 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Trichomonas vaginalis cyclin D, putative 0.004 0.001 0.009
Brugia malayi beta-lactamase family protein 0.0076 0.005 0.075
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Trichomonas vaginalis endoplasmin, putative 0.0052 0.0024 0.0289
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0077 0.0051 0.0135
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0019 0.0284
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0048 0.0019 0.0019
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0121 0.0101 0.1454
Schistosoma mansoni amine GPCR 0.0048 0.0019 0.0284
Onchocerca volvulus 0.0099 0.0076 0.1606
Echinococcus granulosus neuropeptide Y receptor 0.0048 0.0019 0.0019
Echinococcus granulosus tachykinin peptides receptor 99D 0.0048 0.0019 0.0019
Onchocerca volvulus 0.004 0.001 0.022
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.001 0.0086
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0121 0.0101 0.0101
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.001 0.0016
Onchocerca volvulus 0.0048 0.0019 0.0398
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.001 0.0086
Schistosoma mansoni neuropeptide receptor 0.0048 0.0019 0.0284
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0067 0.0041 0.0101
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0048 0.0019 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0396 0.0405 0.6068
Schistosoma mansoni hypothetical protein 0.0031 0.0000073185 0.0001
Schistosoma mansoni neuropeptide f receptor 76f 0.0048 0.0019 0.0284
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0121 0.0101 0.1454
Brugia malayi beta-lactamase 0.0076 0.005 0.075
Schistosoma mansoni hypothetical protein 0.0031 0.0000073185 0.0001
Mycobacterium tuberculosis Probable hydrolase 0.0076 0.005 0.0809
Brugia malayi neuropeptide F receptor 0.0048 0.0019 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Trichomonas vaginalis cyclins, putative 0.004 0.001 0.009
Schistosoma mansoni hypothetical protein 0.0275 0.0271 0.4072
Echinococcus multilocularis cyclins 0.004 0.001 0.001
Schistosoma mansoni amine GPCR 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.0038 0.0008 0.0116
Leishmania major phosphatidylinositol 4-kinase, putative 0.0121 0.0101 0.0266
Schistosoma mansoni hypothetical protein 0.0323 0.0324 0.4867
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Echinococcus multilocularis G protein coupled receptor 139 0.0048 0.0019 0.0019
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0121 0.0101 0.1454
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Trypanosoma brucei Heat shock protein 83, putative 0.0085 0.006 0.0838
Mycobacterium leprae Probable lipase LipE 0.0076 0.005 0.1535
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Loa Loa (eye worm) neuropeptide F receptor 0.0048 0.0019 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.001 0.0016
Brugia malayi Tachykinin-like peptides receptor 99D 0.0048 0.0019 0.0284
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0035 0.0004 0.0094
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0076 0.005 0.075
Schistosoma mansoni biogenic amine (5HT) receptor 0.0048 0.0019 0.0284
Toxoplasma gondii FATC domain-containing protein 0.0356 0.036 0.5386
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.005 0.0688
Echinococcus multilocularis g-protein coupled receptor 0.0048 0.0019 0.0019
Loa Loa (eye worm) phosphatidylinositol 3 0.0121 0.0101 0.1511
Onchocerca volvulus 0.0048 0.0019 0.0398
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 0.0019 0.0019
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.005 0.0688
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0076 0.005 0.075
Schistosoma mansoni opsin-like receptor 0.0048 0.0019 0.0284
Plasmodium vivax hypothetical protein, conserved 0.0076 0.005 0.4728
Echinococcus multilocularis G-protein coupled receptor, putative 0.0048 0.0019 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.005 0.0131
Echinococcus multilocularis cyclins 0.004 0.001 0.001
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0121 0.0101 0.1381
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0019 0.0284
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0121 0.0101 0.1511
Trypanosoma brucei unspecified product 0.004 0.001 0.0086
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0121 0.0101 0.0277
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0077 0.0051 1
Plasmodium falciparum heat shock protein 90 0.0085 0.006 0.5759
Onchocerca volvulus Neuropeptide F receptor homolog 0.0048 0.0019 0.0398
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0121 0.0101 0.0277
Loa Loa (eye worm) neuropeptide F receptor 0.0048 0.0019 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0275 0.0271 0.4032
Echinococcus granulosus peptide allatostatin:somatostatin 0.0048 0.0019 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0121 0.0101 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Plasmodium vivax hypothetical protein 0.0121 0.0101 1
Echinococcus granulosus heat shock protein 90 0.0067 0.0041 0.0041
Trypanosoma brucei heat shock protein 90, putative 0.0085 0.006 0.0838
Echinococcus multilocularis g protein coupled receptor 0.0048 0.0019 0.0019
Echinococcus granulosus tm gpcr rhodopsin 0.0048 0.0019 0.0019
Leishmania major phosphatidylinositol kinase, putative 0.0121 0.0101 0.0266
Echinococcus multilocularis heat shock protein 0.0085 0.006 0.006
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.004 0.001 0.0155
Brugia malayi hypothetical protein 0.0048 0.0019 0.0284
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0121 0.0101 0.1511
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0019 0.0284
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0631 0.0665 0.1832
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 0.0019 0.0019
Trichomonas vaginalis heat shock protein, putative 0.0052 0.0024 0.0289
Mycobacterium tuberculosis Probable lipase LipD 0.0076 0.005 0.0809
Brugia malayi neuropeptide F receptor 0.0048 0.0019 0.0284
Brugia malayi sulfakinin receptor protein 0.0048 0.0019 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Echinococcus multilocularis orexin receptor type 2 0.0048 0.0019 0.0019
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.9055 1 1
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0121 0.0101 0.1454
Trypanosoma cruzi heat shock protein 90, putative 0.0085 0.006 0.0159
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0048 0.0019 0.0284
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0121 0.0101 0.1454
Brugia malayi follicle stimulating hormone receptor 0.0273 0.0269 0.4044
Echinococcus granulosus 7tm_1 domain containing protein 0.0048 0.0019 0.0019
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.001 0.001
Trypanosoma cruzi heat shock protein 85, putative 0.0085 0.006 0.0159
Brugia malayi Dopamine receptor protein 2 0.0048 0.0019 0.0284
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.005 0.075
Onchocerca volvulus 0.0048 0.0019 0.0398
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0048 0.0019 0.0284
Giardia lamblia Grp94/Hsp90 0.0067 0.0041 0.0467
Mycobacterium ulcerans heat shock protein 90 0.0067 0.0041 0.7429
Schistosoma mansoni endoplasmin 0.0085 0.006 0.0899
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Brugia malayi hypothetical protein 0.0048 0.0019 0.0284
Echinococcus multilocularis geminin 0.0164 0.0147 0.0147
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0048 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.001 0.0086
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0051 0.0709
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Schistosoma mansoni heat shock protein 0.0085 0.006 0.0899
Trichomonas vaginalis PIKK family atypical protein kinase 0.0121 0.0101 0.1454
Entamoeba histolytica hypothetical protein 0.0121 0.0101 0.1454
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0121 0.0101 0.1454
Schistosoma mansoni neuropeptide F-like receptor 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0121 0.0101 0.1454
Entamoeba histolytica hypothetical protein 0.0072 0.0046 0.0629
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0121 0.0101 0.1511
Schistosoma mansoni alpha-1 adrenergic receptor 0.0048 0.0019 0.0284
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0005 0.0005
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.0121 0.1822
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0048 0.0019 0.0019
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0631 0.0665 0.1903
Toxoplasma gondii heat shock protein HSP90 0.0085 0.006 0.0838
Trypanosoma cruzi heat shock protein 90, putative 0.005 0.0021 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0121 0.0101 0.0101
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0035 0.0004 0.0004
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0273 0.0269 0.4044
Echinococcus granulosus heat shock protein 90 0.0085 0.006 0.006
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0121 0.0101 0.1454
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0067 0.0041 0.0041
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0631 0.0665 0.1903
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0048 0.0019 0.0284
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 0.0019 0.0284
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0048 0.0019 0.0284
Schistosoma mansoni adenoreceptor 0.0048 0.0019 0.0284
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.005 0.075
Echinococcus multilocularis sex peptide receptor 0.0048 0.0019 0.0019
Entamoeba histolytica cyclin, putative 0.004 0.001 0.009
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0067 0.0041 0.0622
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0048 0.0019 0.0019
Loa Loa (eye worm) beta-lactamase 0.0076 0.005 0.075
Schistosoma mansoni ap endonuclease 0.0077 0.0051 0.0771
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.001 0.0086
Loa Loa (eye worm) phosphatidylinositol 3 0.0631 0.0665 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0121 0.0101 1
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Brugia malayi larval opioid receptor 0.0048 0.0019 0.0284
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0048 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0069 0.0043 0.0645
Trichomonas vaginalis cyclins, putative 0.004 0.001 0.009
Plasmodium vivax endoplasmin, putative 0.0085 0.006 0.5759
Echinococcus multilocularis cyclins 0.004 0.001 0.001
Trichomonas vaginalis cyclins, putative 0.004 0.001 0.009
Giardia lamblia Hypothetical protein 0.004 0.001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Echinococcus multilocularis neuropeptide receptor A26 0.0048 0.0019 0.0019
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0121 0.0101 0.0277
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0051 0.4874
Onchocerca volvulus 0.0048 0.0019 0.0398
Schistosoma mansoni amine GPCR 0.0048 0.0019 0.0284
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0121 0.0101 0.1511
Schistosoma mansoni neuropeptide receptor 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.004 0.001 0.0152
Mycobacterium ulcerans beta-lactamase 0.0076 0.005 0.9659
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0048 0.0019 0.0284
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0121 0.0101 0.1454
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Entamoeba histolytica hypothetical protein 0.0072 0.0046 0.0629
Echinococcus granulosus g protein coupled receptor 0.0048 0.0019 0.0019
Trichomonas vaginalis heat shock protein, putative 0.0067 0.0041 0.0549
Brugia malayi ORL1-like opioid receptor 0.0048 0.0019 0.0284
Onchocerca volvulus 0.0048 0.0019 0.0398
Mycobacterium tuberculosis Probable esterase LipL 0.0076 0.005 0.0809
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0077 0.0051 0.0709
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0048 0.0019 0.0019
Brugia malayi hypothetical protein 0.0487 0.0506 0.761
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0121 0.0121
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0356 0.036 0.5417
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Brugia malayi putative neuropeptide receptor 0.0048 0.0019 0.0284
Echinococcus granulosus cyclins 0.004 0.001 0.001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0121 0.1822
Loa Loa (eye worm) cyclin domain-containing protein 0.004 0.001 0.0157
Echinococcus multilocularis neuropeptide FF receptor 2 0.0048 0.0019 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.001 0.0086
Schistosoma mansoni heat shock protein 0.0085 0.006 0.0899
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0631 0.0665 1
Echinococcus multilocularis endoplasmin 0.0067 0.0041 0.0041
Onchocerca volvulus 0.0048 0.0019 0.0398
Loa Loa (eye worm) phosphatidylinositol 3 0.0121 0.0101 0.1511
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0053 0.5102
Echinococcus granulosus cyclin B 0.004 0.001 0.001
Echinococcus granulosus cyclins 0.004 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0019 0.0284
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0396 0.0405 0.6068
Loa Loa (eye worm) TYRA-2 protein 0.0048 0.0019 0.0284
Echinococcus granulosus serine protein kinase ATM 0.0356 0.036 0.036
Leishmania major hypothetical protein, conserved 0.0076 0.005 0.0126
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Onchocerca volvulus 0.0048 0.0019 0.0398
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.001 0.0086
Toxoplasma gondii target of rapamycin (TOR), putative 0.0631 0.0665 1
Brugia malayi Serotonin receptor 0.0048 0.0019 0.0284
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0121 0.0121
Trichomonas vaginalis cyclin B, putative 0.004 0.001 0.009
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0077 0.0051 1
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0035 0.0004 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0019 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Echinococcus multilocularis neuropeptides capa receptor 0.0048 0.0019 0.0019
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0048 0.0019 0.0284
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0631 0.0665 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0048 0.0019 0.0019
Trypanosoma brucei heat shock protein, putative 0.0085 0.006 0.0838
Echinococcus multilocularis heat shock protein 90 0.0085 0.006 0.006
Leishmania major phosphatidylinositol 3-kinase, putative 0.0121 0.0101 0.0266
Brugia malayi GnHR receptor homolog 0.0048 0.0019 0.0284
Schistosoma mansoni biogenic amine receptor 0.0048 0.0019 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0031 0.0031
Schistosoma mansoni neuropeptide receptor 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Trypanosoma brucei DNA polymerase eta, putative 0.004 0.001 0.0086
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Echinococcus multilocularis fmrfamide receptor 0.0048 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Entamoeba histolytica heat shock protein 90, putative 0.0085 0.006 0.0838
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0053 0.0141
Mycobacterium tuberculosis Conserved protein 0.0076 0.005 0.0809
Loa Loa (eye worm) G-protein coupled receptor 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.0076 0.005 0.075
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0076 0.005 0.0809
Loa Loa (eye worm) phosphatidylinositol 3 0.0121 0.0101 0.1511
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.001 0.0086
Trypanosoma cruzi cyclin, putative 0.004 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0076 0.005 0.075
Onchocerca volvulus 0.0076 0.005 0.1051
Loa Loa (eye worm) phosphatidylinositol 3 0.0631 0.0665 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.001 0.0152
Mycobacterium tuberculosis Conserved protein 0.0076 0.005 0.0809
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.004 0.001 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0356 0.036 0.5386
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0121 0.0101 0.0101
Brugia malayi FAT domain containing protein 0.0275 0.0271 0.4072
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0048 0.0019 0.0284
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0121 0.1822
Trichomonas vaginalis conserved hypothetical protein 0.004 0.001 0.009
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0121 0.0101 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0631 0.0665 1
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0121 0.0101 0.1454
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Echinococcus multilocularis g protein coupled receptor 0.0048 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0035 0.0005 0.0079
Brugia malayi exodeoxyribonuclease III family protein 0.0077 0.0051 0.0771
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0631 0.0665 0.1832
Trypanosoma cruzi heat shock protein 85, putative 0.0085 0.006 0.0159
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0121 0.0101 0.0277
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0121 0.0101 0.1454
Brugia malayi hypothetical protein 0.0048 0.0019 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0356 0.036 0.5386
Echinococcus granulosus tumor protein p63 0.0333 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0097 0.0074 0.1107
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.001 0.0157
Loa Loa (eye worm) runx1 0.0058 0.003 0.0448
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0121 0.0101 0.0101
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0019 0.0019
Trichomonas vaginalis cyclin B, putative 0.004 0.001 0.009
Echinococcus granulosus beta LACTamase domain containing family member 0.0076 0.005 0.005
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0121 0.0101 0.0101
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0356 0.036 0.5386
Schistosoma mansoni hypothetical protein 0.0031 0.0000073185 0.0001
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0000073185 0.0000073185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Onchocerca volvulus 0.0076 0.005 0.1051
Echinococcus granulosus orexin receptor type 2 0.0048 0.0019 0.0019
Loa Loa (eye worm) heat shock protein 75 0.0035 0.0004 0.0067
Loa Loa (eye worm) hypothetical protein 0.0371 0.0377 0.5668
Echinococcus granulosus fmrfamide receptor 0.0048 0.0019 0.0019
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0121 0.0101 0.1511
Giardia lamblia Heat shock protein HSP 90-alpha 0.0067 0.0041 0.0467
Echinococcus multilocularis neuropeptide s receptor 0.0048 0.0019 0.0019
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0631 0.0665 1
Echinococcus multilocularis cyclin b3 0.004 0.001 0.001
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.005 0.0688
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0053 0.5102
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Onchocerca volvulus 0.0459 0.0474 1
Schistosoma mansoni hypothetical protein 0.0048 0.0019 0.0284
Trypanosoma brucei heat shock protein, putative 0.0085 0.006 0.0838
Loa Loa (eye worm) phosphatidylinositol kinase 0.0121 0.0101 0.1511
Brugia malayi putative neuropeptide receptor NPR1 0.0048 0.0019 0.0284
Onchocerca volvulus 0.0048 0.0019 0.0398
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0097 0.0074 0.1107
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0121 0.0101 1
Brugia malayi Melatonin receptor type 1A 0.0048 0.0019 0.0284
Echinococcus granulosus geminin 0.0164 0.0147 0.0147
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0121 0.0101 0.0277
Mycobacterium tuberculosis Probable lipase LipE 0.0076 0.005 0.0809
Toxoplasma gondii heat shock protein 90, putative 0.0085 0.006 0.0838
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.001 0.0157
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0396 0.0405 0.6068
Brugia malayi Endoplasmin precursor 0.0085 0.006 0.0899
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0077 0.0051 0.013
Brugia malayi hypothetical protein 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.0076 0.005 0.075
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0275 0.0271 0.0271
Brugia malayi hypothetical protein 0.0459 0.0474 0.7133
Loa Loa (eye worm) hypothetical protein 0.0356 0.036 0.5417
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 0.0019 0.0019
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0097 0.0074 0.1107
Echinococcus granulosus biogenic amine 5HT receptor 0.0048 0.0019 0.0019
Onchocerca volvulus 0.0048 0.0019 0.0398
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0121 0.0101 0.1381
Leishmania major heat shock protein 83-1 0.0085 0.006 0.0153
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.001 0.0086
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0121 0.0101 0.1454
Onchocerca volvulus 0.0076 0.005 0.1051
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0121 0.0101 0.1454
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0631 0.0665 0.1903
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.001 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0356 0.036 0.1025
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0631 0.0665 1
Trichomonas vaginalis cyclin D, putative 0.004 0.001 0.009
Brugia malayi hypothetical protein 0.0048 0.0019 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0396 0.0405 0.6068
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0275 0.0271 0.0271
Schistosoma mansoni DNA polymerase eta 0.004 0.001 0.0152
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0077 0.0051 0.0051
Onchocerca volvulus 0.0121 0.0101 0.2119
Brugia malayi hypothetical protein 0.0048 0.0019 0.0284
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.001 0.0157
Schistosoma mansoni hypothetical protein 0.0121 0.0101 0.1511
Trichomonas vaginalis PIKK family atypical protein kinase 0.0631 0.0665 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0048 0.0019 0.0019
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0121 0.0101 0.1454
Schistosoma mansoni hypothetical protein 0.0048 0.0019 0.0284
Echinococcus granulosus dna polymerase kappa 0.004 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0076 0.005 0.075
Giardia lamblia Hypothetical protein 0.0121 0.0101 0.1381
Echinococcus multilocularis heat shock protein 90 0.0067 0.0041 0.0041
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0121 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0284
Echinococcus multilocularis neuropeptide Y receptor 0.0048 0.0019 0.0019

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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