Detailed information for compound 673051

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 427.27 | Formula: C16H15BrN2O5S
  • H donors: 0 H acceptors: 5 LogP: 3.68 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(C1=CC(=NS(=O)(=O)c2cccc(c2)[N+](=O)[O-])C(=C(C1=O)Br)C)C
  • InChi: 1S/C16H15BrN2O5S/c1-9(2)13-8-14(10(3)15(17)16(13)20)18-25(23,24)12-6-4-5-11(7-12)19(21)22/h4-9H,1-3H3/b18-14+
  • InChiKey: XWMUCUFPELZASD-NBVRZTHBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0211 1
Schistosoma mansoni smad1 5 8 and 0.0013 0.0034 0.006
Onchocerca volvulus 0.0015 0.0077 0.0069
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0031 0.037 0.0712
Loa Loa (eye worm) hypothetical protein 0.0025 0.025 0.048
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0014 0.0041 0.0079
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0079 0.1275 1
Toxoplasma gondii protein kinase, putative 0.0285 0.5196 1
Loa Loa (eye worm) hypothetical protein 0.0283 0.5157 1
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0211 0.0415
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0017
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0015 0.0077 0.0186
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0015 0.0077 0.0071
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0017 0.0098 0.0084
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Schistosoma mansoni chromobox protein 0.0065 0.1022 0.2929
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0041 0.0569 0.1099
Schistosoma mansoni sugar transporter 0.0014 0.0053 0.0114
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0377 0.0365
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0211 0.1566
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.037 0.0452
Echinococcus granulosus dna polymerase kappa 0.0017 0.0098 0.0093
Echinococcus multilocularis FTZ F1 alpha 0.0015 0.0077 0.0071
Brugia malayi hypothetical protein 0.0014 0.0053 0.0092
Brugia malayi ecdysteroid receptor 0.0015 0.0077 0.0139
Loa Loa (eye worm) hypothetical protein 0.0089 0.147 0.2846
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0015 0.0077 0.0144
Echinococcus granulosus MAGUK p55 subfamily 0.0012 0.0013 0.0002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0015 0.0077 0.0186
Echinococcus multilocularis guanylate kinase 0.0012 0.0013 0.0002
Brugia malayi guanylate kinase 0.0012 0.0013 0.0015
Loa Loa (eye worm) heterochromatin protein 1 0.0065 0.1022 0.1977
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0053 0.0092
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0089 0.147 0.4229
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0079 0.1275 0.3664
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0053 0.0312
Loa Loa (eye worm) latrophilin receptor protein 2 0.009 0.1484 0.2873
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0163 0.2879 0.5529
Leishmania major DNA polymerase kappa, putative 0.0017 0.0098 0.0668
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0283 0.5157 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0538 1 1
Onchocerca volvulus 0.0014 0.0053 0.0007
Trypanosoma cruzi DNA polymerase kappa, putative 0.0017 0.0098 0.0668
Mycobacterium tuberculosis Conserved hypothetical protein 0.0017 0.0098 0.0177
Onchocerca volvulus 0.0014 0.0053 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0015 0.0077 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0098 0.0765
Trypanosoma cruzi hexose transporter 0.0031 0.0377 0.2886
Chlamydia trachomatis hypothetical protein 0.0016 0.0091 0.394
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Echinococcus multilocularis neuropeptide receptor A26 0.05 0.9276 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0015 0.0077 0.0186
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0027 0.0294 0.0305
Echinococcus multilocularis solute carrier family 22 0.0014 0.0053 0.0044
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0015 0.0077 0.0071
Brugia malayi MH2 domain containing protein 0.0194 0.3463 0.6711
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.003 0.0358 0.0374
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0211 0.1566
Toxoplasma gondii sugar transporter ST1 0.0014 0.0053 0.0076
Schistosoma mansoni lamin 0.0025 0.0257 0.0706
Echinococcus multilocularis 55 kDa erythrocyte membrane protein 0.0012 0.0013 0.0002
Leishmania major glucose transporter, lmgt1 0.0031 0.0377 0.2886
Onchocerca volvulus 0.0014 0.0053 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0015 0.0077 0.0139
Echinococcus granulosus neuropeptide s receptor 0.05 0.9276 1
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0453 0.3487
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0275 0.0262
Schistosoma mansoni thyroid hormone receptor 0.0015 0.0077 0.0186
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0015 0.0077 0.0071
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Loa Loa (eye worm) sugar transporter 0.0101 0.1699 0.3291
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0015 0.0077 0.0144
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0079 0.1275 0.1264
Brugia malayi Sugar transporter family protein 0.0014 0.0053 0.0092
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0017 0.0098 0.0245
Schistosoma mansoni hypothetical protein 0.009 0.1484 0.427
Echinococcus granulosus neuropeptide receptor A26 0.05 0.9276 1
Brugia malayi MH1 domain containing protein 0.0013 0.0034 0.0055
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.003 0.0358 0.0345
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0054 0.0809 0.6345
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0211 0.0381
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Onchocerca volvulus Cell death protein 3 homolog 0.0033 0.0418 0.0932
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0015 0.0077 0.0139
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0569 0.1614
Onchocerca volvulus 0.0039 0.0517 0.1183
Onchocerca volvulus Bile acid receptor homolog 0.0015 0.0077 0.0069
Loa Loa (eye worm) hypothetical protein 0.0015 0.0077 0.0144
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0015 0.0077 0.0144
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0017 0.0098 0.0177
Echinococcus granulosus CAAX prenyl protease 2 0.0079 0.1275 0.1364
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0038 0.0499 0.0526
Echinococcus granulosus peripheral plasma membrane protein CASK 0.0014 0.005 0.0041
Brugia malayi chromobox protein homolog 3 0.0037 0.0478 0.0916
Echinococcus granulosus chromobox protein 1 0.0065 0.1022 0.109
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0015 0.0077 0.0144
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.0053 0.0039
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0079 0.1275 0.3664
Echinococcus multilocularis mothers against decapentaplegic 5 0.0013 0.0034 0.0024
Brugia malayi nuclear receptor NHR-88 0.0015 0.0077 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0377 0.0365
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.0014 0.005 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0015 0.0077 0.0139
Loa Loa (eye worm) hypothetical protein 0.0033 0.0418 0.0804
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0035 0.0453 0.0849
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.003 0.0358 0.0345
Loa Loa (eye worm) hypothetical protein 0.0079 0.1275 0.2468
Mycobacterium ulcerans DNA polymerase IV 0.0017 0.0098 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0053 0.0039
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0358 0.1001
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0014 0.0041 0.0216
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0089 0.147 0.4229
Echinococcus multilocularis high voltage activated calcium channel beta 0.0134 0.232 0.2491
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0015 0.0077 0.0139
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0017 0.0098 0.0183
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0077 0.0071
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0053 0.0044
Toxoplasma gondii sugar transporter ST3 0.0014 0.0053 0.0076
Brugia malayi photoreceptor-specific nuclear receptor 0.0015 0.0077 0.0139
Loa Loa (eye worm) MH2 domain-containing protein 0.0013 0.0034 0.006
Loa Loa (eye worm) Smad1 0.0013 0.0034 0.006
Giardia lamblia Hexose transporter 0.0014 0.0053 0.0039
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0015 0.0077 0.0071
Schistosoma mansoni lamin 0.0025 0.0257 0.0706
Brugia malayi Peripheral plasma membrane protein CASK 0.0012 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0136 0.0259
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0015 0.0077 0.0071
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0025 0.0257 0.0492
Trypanosoma brucei glucose transporter, putative 0.0031 0.0377 0.296
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0014 0.0041 0.0034
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0053 0.0114
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0211 0.0215
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0077 0.0139
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0041 0.0031
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.0053 0.0039
Schistosoma mansoni hypothetical protein 0.0048 0.0691 0.1968
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.037 0.0387
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.1699 0.1688
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0031 0.037 0.0689
Loa Loa (eye worm) isocitrate dehydrogenase 0.0014 0.0041 0.0073
Echinococcus multilocularis sodium channel protein 0.0038 0.0499 0.0526
Echinococcus multilocularis caspase 2 0.0033 0.0418 0.0438
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0377 0.2886
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0377 0.0365
Giardia lamblia DINP protein human, muc B family 0.0017 0.0098 0.0084
Echinococcus granulosus chromobox protein 1 0.0065 0.1022 0.109
Brugia malayi Sugar transporter family protein 0.0101 0.1699 0.3287
Echinococcus granulosus high voltage activated calcium channel beta 0.0134 0.232 0.2491
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0015 0.0077 0.0144
Echinococcus multilocularis dna polymerase kappa 0.0017 0.0098 0.0093
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0031 0.037 0.0689
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0211 0.0574
Leishmania major hypothetical protein, conserved 0.0014 0.0053 0.0312
Echinococcus granulosus TGF beta signal transducer SmadC 0.0013 0.0034 0.0024
Brugia malayi Guanylate kinase family protein 0.0012 0.0013 0.0015
Brugia malayi cytoplasmic intermediate filament protein 0.0013 0.0037 0.0061
Brugia malayi intermediate filament protein 0.0025 0.0257 0.0487
Schistosoma mansoni hypothetical protein 0.0026 0.0285 0.0788
Trichomonas vaginalis chromobox protein, putative 0.0039 0.053 0.0518
Schistosoma mansoni sugar transporter 0.0014 0.0053 0.0114
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0089 0.147 0.1574
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0211 0.0399
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0053 0.0044
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0211 0.0215
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Mycobacterium ulcerans integral membrane protein 0.0016 0.0091 0.0164
Entamoeba histolytica CAAX amino terminal protease family 0.0016 0.0091 0.0078
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Echinococcus multilocularis smad 0.0013 0.0034 0.0024
Echinococcus granulosus disks large 3 0.0012 0.0013 0.0002
Schistosoma mansoni glucose transport protein 0.0101 0.1699 0.4896
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0031 0.037 0.0689
Brugia malayi hypothetical protein 0.0014 0.0053 0.0092
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0538 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0015 0.0077 0.0144
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.009 0.1484 0.1589
Giardia lamblia Sugar-proton symporter 0.0014 0.0053 0.0039
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0031 0.037 0.0712
Schistosoma mansoni smad1 5 8 and 0.0013 0.0034 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0478 0.0465
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Onchocerca volvulus 0.0025 0.0257 0.0524
Echinococcus granulosus lamin 0.0025 0.0257 0.0264
Loa Loa (eye worm) transcription factor SMAD2 0.0194 0.3463 0.6713
Toxoplasma gondii hypothetical protein 0.0016 0.0091 0.015
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0012 0.0019 0.0031
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Echinococcus multilocularis apoptotic protease activating factor 1 0.0033 0.0418 0.0438
Loa Loa (eye worm) hypothetical protein 0.0031 0.037 0.0712
Echinococcus granulosus FTZ F1 alpha 0.0015 0.0077 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0015 0.0077 0.0139
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Loa Loa (eye worm) hypothetical protein 0.0193 0.3457 0.6701
Plasmodium falciparum hexose transporter 0.0101 0.1699 0.2134
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0015 0.0077 0.0139
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0041 0.0569 0.1094
Giardia lamblia Fructose-bisphosphate aldolase 0.0538 1 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Trypanosoma brucei glucose transporter 1E 0.0031 0.0377 0.296
Trypanosoma brucei glucose transporter 2A 0.0031 0.0377 0.296
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0538 1 1
Echinococcus granulosus voltage dependent calcium channel 0.0019 0.0136 0.0135
Echinococcus multilocularis CAAX prenyl protease 2 0.0079 0.1275 0.1364
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0017 0.0098 0.0093
Brugia malayi major facilitator superfamily protein 0.0014 0.0053 0.0092
Loa Loa (eye worm) steroid hormone receptor 0.0015 0.0077 0.0144
Brugia malayi Steroid receptor seven-up type 2 0.0015 0.0077 0.0139
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0014 0.0041 0.0318
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0015 0.0077 0.0139
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0077 0.0071
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0377 0.2886
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0017 0.0098 0.0093
Plasmodium falciparum calcium-dependent protein kinase 1 0.0031 0.037 0.0452
Loa Loa (eye worm) hypothetical protein 0.0015 0.0077 0.0144
Trichomonas vaginalis chromobox protein, putative 0.0039 0.053 0.0518
Loa Loa (eye worm) hypothetical protein 0.009 0.1484 0.2873
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0098 0.0765
Echinococcus granulosus smad 0.0013 0.0034 0.0024
Schistosoma mansoni retinoic acid receptor RXR 0.0015 0.0077 0.0186
Brugia malayi Isocitrate dehydrogenase 0.0014 0.0041 0.0068
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0053 0.0044
Echinococcus multilocularis high voltage activated calcium channel beta 0.0012 0.0013 0.0002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0094 0.0176
Echinococcus granulosus dna polymerase eta 0.0017 0.0098 0.0093
Loa Loa (eye worm) calcium channel 0.0089 0.147 0.2846
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0453 0.3487
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0041 0.0031
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0053 0.0312
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Echinococcus multilocularis isocitrate dehydrogenase 0.0014 0.0041 0.0031
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0015 0.0077 0.0186
Onchocerca volvulus 0.0014 0.0053 0.0007
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0015 0.0077 0.0071
Loa Loa (eye worm) lethal(1)discs large-1 tumor suppressor 0.0012 0.0013 0.002
Trypanosoma brucei glucose transporter, putative 0.0031 0.0377 0.296
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0031 0.037 0.0387
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0211 0.0574
Echinococcus multilocularis guanylate kinase 0.0012 0.0013 0.0002
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0031 0.037 0.0452
Echinococcus multilocularis disks large 1 0.0012 0.0013 0.0002
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0016 0.0091 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0053 0.0039
Echinococcus granulosus voltage dependent calcium channel 0.0089 0.147 0.1574
Trypanosoma brucei glucose transporter, putative 0.0031 0.0377 0.296
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Loa Loa (eye worm) voltage-dependent calcium channel 0.0019 0.0136 0.0259
Brugia malayi CAAX amino terminal protease family protein 0.0079 0.1275 0.2465
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0031 0.037 0.0452
Brugia malayi MH2 domain containing protein 0.0013 0.0034 0.0055
Echinococcus granulosus GPCR family 2 0.009 0.1484 0.1589
Onchocerca volvulus 0.0014 0.0053 0.0007
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.003 0.0358 0.0724
Trypanosoma brucei glucose transporter, putative 0.0031 0.0377 0.296
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0098 0.0765
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.003 0.0358 0.0684
Onchocerca volvulus 0.0014 0.0053 0.0007
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0037 0.0478 0.1084
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0015 0.0077 0.0071
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0101 0.1699 0.1821
Plasmodium falciparum calcium-dependent protein kinase 2 0.0031 0.037 0.0452
Echinococcus granulosus high voltage activated calcium channel beta 0.0012 0.0013 0.0002
Schistosoma mansoni RAR-like nuclear receptor 0.0015 0.0077 0.0186
Schistosoma mansoni Smad4 0.0013 0.0034 0.006
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0453 0.3487
Schistosoma mansoni protein kinase 0.0031 0.037 0.1036
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.037 0.0387
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0013 0.0037 0.0066
Echinococcus multilocularis solute carrier family 22 0.0014 0.0053 0.0044
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0041 0.0569 0.0602
Loa Loa (eye worm) hypothetical protein 0.0016 0.0094 0.0176
Echinococcus granulosus guanylate kinase 0.0012 0.0013 0.0002
Entamoeba histolytica CAAX amino terminal protease family 0.0016 0.0091 0.0078
Brugia malayi Pre-SET motif family protein 0.0028 0.0314 0.0599
Onchocerca volvulus 0.0025 0.0257 0.0524
Onchocerca volvulus 0.0014 0.0053 0.0007
Echinococcus granulosus histone lysine methyltransferase setb 0.0028 0.0314 0.0326
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0031 0.037 0.0707
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0275 0.5011 0.9716
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0211 0.0198
Loa Loa (eye worm) hypothetical protein 0.003 0.0358 0.0689
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0015 0.0077 0.0069
Echinococcus multilocularis neuropeptide s receptor 0.05 0.9276 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0015 0.0077 0.0139
Trichomonas vaginalis CAMK family protein kinase 0.0031 0.037 0.0357
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0538 1 1
Schistosoma mansoni MAGUK homolog 0.0014 0.005 0.0106
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.037 0.0387
Loa Loa (eye worm) MH1 domain-containing protein 0.0013 0.0034 0.006
Plasmodium falciparum protein kinase 6 0.0428 0.7914 1
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0098 0.0179
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0053 0.0092
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0334 0.0348
Echinococcus granulosus solute carrier family 22 0.0014 0.0053 0.0044
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0089 0.147 0.1574
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0211 0.025
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.0091 0.0164
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Onchocerca volvulus 0.0014 0.0053 0.0007
Plasmodium falciparum proline--tRNA ligase 0.0035 0.0453 0.0557
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.003 0.0358 0.0684
Plasmodium vivax protease, putative 0.0016 0.0091 0.0099
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0377 0.296
Schistosoma mansoni terminal deoxycytidyl transferase 0.0017 0.0098 0.0245
Brugia malayi hypothetical protein 0.0033 0.0418 0.08
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Brugia malayi abnormal cell lineage protein 2 0.0012 0.0013 0.0015
Plasmodium vivax SET domain protein, putative 0.0028 0.0314 0.0381
Echinococcus granulosus solute carrier family 22 0.0014 0.0053 0.0044
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0538 1 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.002
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.1699 0.1821
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0016 0.0091 0.0164
Echinococcus granulosus disks large 1 0.0012 0.0013 0.0002
Mycobacterium ulcerans hypothetical protein 0.0016 0.0091 0.0164
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0098 0.0765
Schistosoma mansoni caspase-7 (C14 family) 0.0033 0.0418 0.1174
Plasmodium vivax hexose transporter 0.0101 0.1699 0.2134
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0054 0.0809 0.6307
Trypanosoma brucei DNA polymerase IV, putative 0.0017 0.0098 0.0765
Echinococcus multilocularis dna polymerase eta 0.0017 0.0098 0.0093
Echinococcus granulosus mothers against decapentaplegic 5 0.0013 0.0034 0.0024
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0146 0.028
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Loa Loa (eye worm) hypothetical protein 0.0025 0.0257 0.0492
Schistosoma mansoni protein kinase 0.0031 0.037 0.1036
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0028 0.0314 0.0326
Loa Loa (eye worm) hypothetical protein 0.0015 0.0077 0.0144
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0014 0.0041 0.0031
Mycobacterium tuberculosis Probable integral membrane protein 0.0016 0.0091 0.0164
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0453 0.3487
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0334 0.0348
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0195 0.3483 0.6751
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0089 0.147 0.1574
Trypanosoma brucei DNA polymerase eta, putative 0.0017 0.0098 0.0765
Brugia malayi Latrophilin receptor protein 2 0.009 0.1484 0.2869
Trypanosoma brucei unspecified product 0.0017 0.0098 0.0765
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0283 0.5157 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0079 0.1275 1
Echinococcus multilocularis MAGUK p55 subfamily 0.0012 0.0013 0.0002
Echinococcus multilocularis MAGUK p55 subfamily 0.0012 0.0013 0.0002
Brugia malayi steroid hormone receptor 0.0015 0.0077 0.0139
Trypanosoma brucei CAAX amino terminal protease, putative 0.0079 0.1275 1
Echinococcus multilocularis solute carrier family 22 0.0014 0.0053 0.0044
Trypanosoma cruzi DNA polymerase eta, putative 0.0017 0.0098 0.0668
Schistosoma mansoni chromobox protein 0.0065 0.1022 0.2929
Mycobacterium ulcerans sugar transporter 0.0014 0.0053 0.0083
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Schistosoma mansoni hypothetical protein 0.009 0.1484 0.427
Brugia malayi Pre-SET motif family protein 0.0195 0.3483 0.675
Schistosoma mansoni protein kinase 0.0031 0.037 0.1036
Echinococcus multilocularis lamin dm0 0.0025 0.0257 0.0264
Brugia malayi latrophilin 2 splice variant baaae 0.0193 0.3457 0.6699
Brugia malayi Intermediate filament tail domain containing protein 0.0025 0.0257 0.0487
Toxoplasma gondii hypothetical protein 0.0016 0.0094 0.0155
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0538 1 1
Treponema pallidum fructose-bisphosphate aldolase 0.0538 1 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.1699 0.1821
Schistosoma mansoni hypothetical protein 0.0101 0.1699 0.4896
Onchocerca volvulus 0.0014 0.0053 0.0007
Schistosoma mansoni glucose transport protein 0.0101 0.1699 0.4896
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0017 0.0098 0.0668
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0377 0.2886
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.009 0.1484 0.1589
Onchocerca volvulus 0.0014 0.0053 0.0007
Trichomonas vaginalis chromobox protein, putative 0.0065 0.1022 0.101
Schistosoma mansoni smad 0.0013 0.0034 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0478 0.0465
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Schistosoma mansoni sugar transporter 0.0014 0.0053 0.0114
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0098 0.0765
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0039 0.0517 0.1462
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0014 0.0041 0.0034
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.037 0.0387
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.003 0.0358 0.0374
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.009 0.1484 0.1589
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Loa Loa (eye worm) hypothetical protein 0.0015 0.0077 0.0144
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0014 0.0041 0.0216
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Schistosoma mansoni hypothetical protein 0.0033 0.0418 0.1174
Echinococcus multilocularis thyroid hormone receptor alpha 0.0015 0.0077 0.0071
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.0053 0.0083
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0053 0.0096
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0077 0.0071
Schistosoma mansoni hypothetical protein 0.009 0.1484 0.427
Loa Loa (eye worm) hypothetical protein 0.0033 0.0418 0.0804
Onchocerca volvulus 0.0029 0.0328 0.0704
Schistosoma mansoni hypothetical protein 0.009 0.1484 0.427
Toxoplasma gondii isocitrate dehydrogenase 0.0014 0.0041 0.0053
Leishmania major glucose transporter, lmgt2 0.0031 0.0377 0.2886
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0053 0.0312
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0077 0.0071
Brugia malayi Sugar transporter family protein 0.0014 0.0053 0.0092
Brugia malayi MH1 domain containing protein 0.0013 0.0034 0.0055
Echinococcus granulosus MAGUK p55 subfamily 0.0012 0.0013 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0275 0.0262
Giardia lamblia Prolyl-tRNA synthetase 0.003 0.0358 0.0345
Leishmania major DNA polymerase eta, putative 0.0017 0.0098 0.0668
Echinococcus multilocularis Smad4 0.0013 0.0034 0.0024
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0108 0.0751
Loa Loa (eye worm) hypothetical protein 0.0015 0.0077 0.0144
Echinococcus multilocularis disks large 3 0.0012 0.0013 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0015 0.0077 0.0144
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Brugia malayi hypothetical protein 0.0012 0.0013 0.0015
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0158 0.0145
Echinococcus multilocularis solute carrier family 22 0.0014 0.0053 0.0044
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0079 0.1275 1
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0377 0.0365
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0014 0.0041 0.0318
Echinococcus granulosus solute carrier family 22 0.0014 0.0053 0.0044
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0031 0.037 0.2901
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Schistosoma mansoni coup transcription factor 0.0015 0.0077 0.0186
Entamoeba histolytica deoxycytidyl transferase, putative 0.0017 0.0098 0.0084
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Entamoeba histolytica protein kinase, putative 0.0031 0.037 0.0357
Plasmodium vivax CDK-related protein kinase 6, putative 0.0428 0.7914 1
Onchocerca volvulus 0.0014 0.0053 0.0007
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0089 0.147 0.1574
Echinococcus granulosus lamin dm0 0.0025 0.0257 0.0264
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0377 0.0365
Echinococcus multilocularis musashi 0.0025 0.0257 0.0264
Echinococcus multilocularis GPCR, family 2 0.009 0.1484 0.1589
Trypanosoma brucei DNA polymerase IV, putative 0.0017 0.0098 0.0765
Onchocerca volvulus 0.0033 0.0418 0.0932
Entamoeba histolytica CAAX prenyl protease family 0.0079 0.1275 0.1264
Echinococcus multilocularis lamin 0.0025 0.0257 0.0264
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0014 0.0041 0.0031
Brugia malayi MH2 domain containing protein 0.0013 0.0034 0.0055
Leishmania major protein kinase, putative 0.0031 0.037 0.2826
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0014 0.0053 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0377 0.296
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0098 0.0765
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0569 0.1614
Trypanosoma cruzi DNA polymerase kappa, putative 0.0017 0.0098 0.0668
Onchocerca volvulus 0.0014 0.0053 0.0007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0569 0.1614
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0053 0.0076
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0013 0.0034 0.0024
Loa Loa (eye worm) MH2 domain-containing protein 0.0194 0.3463 0.6713
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0028 0.0314 0.0326
Schistosoma mansoni DNA polymerase eta 0.0017 0.0098 0.0245
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0314 0.0873
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0134 0.232 0.6698
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.037 0.0387
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.009 0.1484 0.1589
Echinococcus multilocularis chromobox protein 1 0.0065 0.1022 0.109
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0377 0.296
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.037 0.0387
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0098 0.0765
Loa Loa (eye worm) intermediate filament protein 0.0025 0.0257 0.0492
Echinococcus multilocularis voltage dependent calcium channel 0.0089 0.147 0.1574
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0358 0.1001
Onchocerca volvulus 0.0014 0.0053 0.0007
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.1699 0.1821
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0015 0.0077 0.0139
Brugia malayi Guanylate kinase family protein 0.0012 0.0013 0.0015
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0275 0.5011 0.9716
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0211 0.0198
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Loa Loa (eye worm) hypothetical protein 0.0029 0.0328 0.063
Trypanosoma brucei glucose transporter, putative 0.0031 0.0377 0.296
Toxoplasma gondii facilitative glucose transporter GT1 0.0101 0.1699 0.3253
Onchocerca volvulus Putative transporter 0.0014 0.0053 0.0007
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.1699 0.1821
Echinococcus granulosus intermediate filament protein 0.0025 0.0257 0.0264
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0014 0.0041 0.0216
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0211 0.0415
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0053 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.037 0.1036
Brugia malayi ZU5 domain containing protein 0.0012 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.002
Leishmania major glucose transporter/membrane transporter D2, putative 0.0031 0.0377 0.2886
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0012 0.0013 0.0002
Loa Loa (eye worm) guanylate kinase 0.0012 0.0013 0.002
Onchocerca volvulus 0.0014 0.0053 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0053 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0098 0.0765
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0453 0.3555
Loa Loa (eye worm) hypothetical protein 0.0023 0.0211 0.0403
Plasmodium falciparum protein kinase 7 0.0285 0.5196 0.656
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0163 0.2879 0.3627
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0089 0.147 0.1574
Mycobacterium ulcerans DNA polymerase IV 0.0017 0.0098 0.0177
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0013 0.0034 0.006
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0053 0.0096
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0053 0.0092
Entamoeba histolytica hypothetical protein 0.0023 0.0211 0.0198
Echinococcus multilocularis General substrate transporter 0.0087 0.143 0.1531
Echinococcus granulosus Smad4 0.0013 0.0034 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0015 0.0077 0.0139
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0014 0.0041 0.0057
Leishmania major glucose transporter, lmgt3 0.0031 0.0377 0.2886
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.0136 0.0238
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0053 0.0312
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.053 0.1218
Schistosoma mansoni glucose transporter 0.0014 0.0053 0.0114
Schistosoma mansoni hypothetical protein 0.0193 0.3457 1
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0098 0.0179
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0015 0.0077 0.0071
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0041 0.0569 0.0602
Plasmodium vivax calcium-dependent protein kinase, putative 0.0031 0.037 0.0452
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Echinococcus granulosus caspase 2 0.0033 0.0418 0.0438
Toxoplasma gondii sugar transporter ST2 0.0014 0.0053 0.0076
Trichomonas vaginalis DNA polymerase eta, putative 0.0017 0.0098 0.0084
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0263 0.4774 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0248 0.0475
Trichomonas vaginalis set domain proteins, putative 0.0222 0.3994 0.3986
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.009 0.1484 0.2869
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0077 0.0186
Trypanosoma brucei glucose transporter, putative 0.0031 0.0377 0.296
Plasmodium vivax proline--tRNA ligase, putative 0.0035 0.0453 0.0557
Brugia malayi Calcitonin receptor-like protein seb-1 0.0283 0.5157 1
Loa Loa (eye worm) peripheral plasma membrane protein CASK 0.0012 0.0013 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0053 0.0039
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0041 0.0569 0.0602
Echinococcus multilocularis ecdysone induced protein 78C 0.0015 0.0077 0.0071
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Echinococcus granulosus guanylate kinase 0.0012 0.0013 0.0002
Echinococcus granulosus apoptotic protease activating factor 1 0.0033 0.0418 0.0438
Trypanosoma brucei guanylate kinase, putative 0.0012 0.0013 0.0104
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Plasmodium vivax sugar transporter, putative 0.0014 0.0053 0.005
Loa Loa (eye worm) guanylate kinase 0.0012 0.0013 0.002
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0211 0.0415
Entamoeba histolytica protein kinase, putative 0.0031 0.037 0.0357
Plasmodium falciparum protease, putative 0.0016 0.0091 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0098 0.0765
Brugia malayi isocitrate dehydrogenase 0.0014 0.0041 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0053 0.0039
Echinococcus granulosus MAGUK p55 subfamily 0.0012 0.0013 0.0002
Trypanosoma brucei guanylate kinase, putative 0.0012 0.0013 0.0104
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0538 1 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0028 0.0314 0.058
Echinococcus granulosus ecdysone induced protein 78C 0.0015 0.0077 0.0071
Trypanosoma brucei glucose transporter, putative 0.0031 0.0377 0.296
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.0053 0.0083
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0096
Plasmodium falciparum mitogen-activated protein kinase 2 0.0163 0.2879 0.3627
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0014 0.0053 0.0083
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0263 0.4774 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0478 0.0921
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.0053 0.0083
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0089 0.147 0.1574
Loa Loa (eye worm) hypothetical protein 0.0028 0.0314 0.0603
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0263 0.4774 1
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0211 0.025
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0089 0.147 0.2842
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0377 0.0365
Brugia malayi Heterochromatin protein 1 0.0065 0.1022 0.1973
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0089 0.147 0.1574
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0053 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0015 0.0077 0.0139
Echinococcus multilocularis 0.0012 0.0013 0.0002
Schistosoma mansoni sugar transporter 0.0014 0.0053 0.0114
Brugia malayi Smad1 0.0013 0.0034 0.0055
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0041 0.0569 0.0602
Brugia malayi nuclear hormone receptor 0.0015 0.0077 0.0139
Loa Loa (eye worm) hypothetical protein 0.0015 0.0077 0.0144
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.0053 0.0413
Schistosoma mansoni steroid hormone receptor ad4bp 0.0015 0.0077 0.0186
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0053 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0377 0.0365
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0015 0.0077 0.0071
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0146 0.028
Echinococcus multilocularis voltage dependent calcium channel 0.0089 0.147 0.1574
Trichomonas vaginalis chromobox protein, putative 0.0065 0.1022 0.101
Plasmodium falciparum calcium-dependent protein kinase 4 0.0031 0.037 0.0452
Echinococcus multilocularis chromobox protein 1 0.0065 0.1022 0.109
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0098 0.0765
Brugia malayi Guanylate kinase family protein 0.0012 0.0013 0.0015
Onchocerca volvulus 0.0014 0.0053 0.0007
Mycobacterium ulcerans hypothetical protein 0.0016 0.0091 0.0164
Schistosoma mansoni thyroid hormone receptor 0.0015 0.0077 0.0186
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.002
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0146 0.028
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.1699 0.1821
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.1699 0.1821
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0211 0.1654
Brugia malayi major facilitator superfamily protein 0.0014 0.0053 0.0092
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Loa Loa (eye worm) sugar transporter 0.0014 0.0053 0.0096
Echinococcus granulosus 55 kDa erythrocyte membrane protein 0.0012 0.0013 0.0002
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0015 0.0077 0.0186
Giardia lamblia Hypothetical protein 0.0079 0.1275 0.1264
Echinococcus granulosus solute carrier family 22 0.0014 0.0053 0.0044
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0053 0.0039
Loa Loa (eye worm) hypothetical protein 0.0015 0.0077 0.0144
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0538 1 1
Schistosoma mansoni intermediate filament proteins 0.0025 0.0257 0.0706
Plasmodium falciparum calcium-dependent protein kinase 3 0.0031 0.037 0.0452
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.002
Onchocerca volvulus 0.0014 0.0053 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0077 0.0144
Schistosoma mansoni glucose transport protein 0.0101 0.1699 0.4896
Toxoplasma gondii isocitrate dehydrogenase 0.0014 0.0041 0.0053
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0314 0.0873
Brugia malayi Cam kinase protein 1 0.0031 0.037 0.0707
Onchocerca volvulus 0.0222 0.3994 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.037 0.0387
Trypanosoma brucei DNA polymerase IV, putative 0.0017 0.0098 0.0765
Brugia malayi hypothetical protein 0.0014 0.0053 0.0092
Trypanosoma brucei glucose transporter, putative 0.0031 0.0377 0.296
Trypanosoma cruzi DNA polymerase kappa, putative 0.0017 0.0098 0.0668
Trypanosoma cruzi DNA polymerase kappa, putative 0.0017 0.0098 0.0668
Echinococcus granulosus General substrate transporter 0.0087 0.143 0.1531
Schistosoma mansoni smad1 5 8 and 0.0013 0.0034 0.006
Schistosoma mansoni voltage-gated cation channel 0.0089 0.147 0.4229
Trypanosoma brucei sugar transporter, putative 0.0014 0.0053 0.0413
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0314 0.0873
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0015 0.0077 0.0186
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0015 0.0077 0.0139
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.1699 0.1821
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0041 0.0031
Toxoplasma gondii hypothetical protein 0.0016 0.0091 0.015
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0014 0.0053 0.0083
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0538 1 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0358 0.0689
Onchocerca volvulus Protein ultraspiracle homolog 0.0015 0.0077 0.0069
Loa Loa (eye worm) hypothetical protein 0.0017 0.0098 0.0183
Toxoplasma gondii CAAX amino terminal protease family protein 0.0016 0.0091 0.015
Echinococcus multilocularis MAGUK p55 subfamily 0.0012 0.0013 0.0002
Brugia malayi Cell death protein 3 precursor 0.0033 0.0418 0.08
Plasmodium falciparum calcium-dependent protein kinase 5 0.0031 0.037 0.0452

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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