Detailed information for compound 732201

Basic information

Technical information
  • TDR Targets ID: 732201
  • Name: N-cyclopropyl-4-methoxy-3-[1-(1-methylsulfany lpropan-2-yl)piperidin-4-yl]oxybenzamide
  • MW: 378.529 | Formula: C20H30N2O3S
  • H donors: 1 H acceptors: 1 LogP: 3.37 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1OC1CCN(CC1)C(CSC)C)C(=O)NC1CC1
  • InChi: 1S/C20H30N2O3S/c1-14(13-26-3)22-10-8-17(9-11-22)25-19-12-15(4-7-18(19)24-2)20(23)21-16-5-6-16/h4,7,12,14,16-17H,5-6,8-11,13H2,1-3H3,(H,21,23)
  • InChiKey: AQQHFQNOUFVHET-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-cyclopropyl-4-methoxy-3-[[1-(1-methyl-2-methylsulfanyl-ethyl)-4-piperidyl]oxy]benzamide
  • N-cyclopropyl-4-methoxy-3-[[1-[1-methyl-2-(methylthio)ethyl]-4-piperidinyl]oxy]benzamide
  • N-cyclopropyl-4-methoxy-3-[[1-[1-methyl-2-(methylthio)ethyl]-4-piperidyl]oxy]benzamide
  • N-cyclopropyl-4-methoxy-3-[1-(1-methylsulfanylpropan-2-yl)piperidin-4-yl]oxy-benzamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Leishmania major glucose transporter, lmgt1 0.0064 0.067 0.8771
Brugia malayi Pre-SET motif family protein 0.0217 0.242 0.8619
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0049 0.0061
Trypanosoma brucei glucose transporter, putative 0.0064 0.067 0.8771
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Schistosoma mansoni hypothetical protein 0.0207 0.2306 0.2829
Toxoplasma gondii sugar transporter ST2 0.0029 0.0268 0.0404
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0148 0.229
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0568 0.2023
Loa Loa (eye worm) hypothetical protein 0.0034 0.0321 0.1143
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0114 0.014
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0063 0.0661 0.0724
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0049 0.0061
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0072 0.0764 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0207 0.2306 0.2829
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0134 0.0134
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Leishmania major acetyl-CoA synthetase, putative 0.0007 0.0013 0.017
Leishmania major acetyl-CoA synthetase, putative 0.0007 0.0013 0.017
Brugia malayi Sugar transporter family protein 0.0029 0.0268 0.0955
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0063 0.0661 0.0661
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0049 0.0061
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0063 0.0661 0.2353
Onchocerca volvulus 0.0007 0.0013 0.0047
Loa Loa (eye worm) 63kd antigen 0.0007 0.0015 0.0052
Plasmodium falciparum protein kinase 7 0.0584 0.6635 0.6635
Plasmodium falciparum asparagine--tRNA ligase 0.0007 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0168 0.1856 0.2276
Chlamydia trachomatis threonine--tRNA ligase 0.0012 0.0068 0.1193
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0015 0.0018
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0029 0.0268 0.5658
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0007 0.0013 0.002
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0012 0.0068 0.0219
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0029 0.0031
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0015 0.0018
Brugia malayi Pre-SET motif family protein 0.0032 0.0297 0.1059
Leishmania major asparaginyl-tRNA synthetase, putative 0.0007 0.0015 0.019
Onchocerca volvulus 0.0029 0.0268 0.0971
Chlamydia trachomatis lysine--tRNA ligase 0.0046 0.0464 1
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0007 0.0013 0.0042
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0148 0.1936
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0297 0.0326
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Trichomonas vaginalis sugar transport protein, putative 0.0029 0.0268 0.0971
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0049 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0049 0.0176
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.05 0.178
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0775 0.095
Plasmodium falciparum calcium-dependent protein kinase 1 0.0063 0.0661 0.0661
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0148 0.0181
Loa Loa (eye worm) hypothetical protein 0.005 0.0513 0.1826
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0007 0.0015 0.0195
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0049 0.0176
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.0068 0.0892
Toxoplasma gondii exonuclease III APE 0.0019 0.0148 0.0223
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0114 0.0125
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0012 0.0068 0.2114
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0062 0.0646 0.2301
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.004 0.0399 0.1444
Brugia malayi beta-lactamase family protein 0.0043 0.0433 0.1543
Leishmania major glucose transporter, lmgt3 0.0064 0.067 0.8771
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.067 0.2426
Echinococcus multilocularis glycyl tRNA synthetase 0.0012 0.0068 0.0075
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0433 0.567
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.0068 0.0103
Schistosoma mansoni hypothetical protein 0.0051 0.0521 0.0639
Schistosoma mansoni hypothetical protein 0.0034 0.0321 0.0394
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0007 0.0015 0.019
Trypanosoma brucei glucose transporter 1E 0.0064 0.067 0.8771
Loa Loa (eye worm) hypothetical protein 0.0017 0.0134 0.0477
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0201 0.4172
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0049 0.0054
Loa Loa (eye worm) hypothetical protein 0.0043 0.0433 0.1543
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0802 0.9128 1
Echinococcus multilocularis dnaJ subfamily B 0.0404 0.4572 0.5009
Echinococcus multilocularis aspartyl tRNA synthetase, cytoplasmic 0.0007 0.0015 0.0016
Echinococcus multilocularis geminin 0.0168 0.1856 0.2033
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0775 0.0849
Schistosoma mansoni hypothetical protein 0.0168 0.1856 0.2276
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0114 0.0114
Mycobacterium ulcerans sugar transporter 0.0029 0.0268 0.5658
Trypanosoma cruzi histidyl-tRNA synthetase 0.0007 0.0015 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0268 0.0971
Schistosoma mansoni glucose transport protein 0.0207 0.2306 0.2829
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0433 0.6704
Onchocerca volvulus 0.0029 0.0268 0.0971
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0009 0.0031
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0114 0.0405
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0049 0.0054
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Loa Loa (eye worm) hypothetical protein 0.0062 0.0646 0.2301
Onchocerca volvulus 0.0007 0.0013 0.0047
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0007 0.0013 0.017
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.001 0.0053 0.0079
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0013 0.017
Plasmodium falciparum proline--tRNA ligase 0.0072 0.0764 0.0764
Toxoplasma gondii propionate-CoA ligase 0.0007 0.0013 0.002
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0063 0.0661 0.2353
Echinococcus multilocularis GPCR, family 2 0.0016 0.0114 0.0124
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0007 0.0013 0.0046
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0049 0.0061
Onchocerca volvulus 0.0048 0.0491 0.1776
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0114 0.149
Trypanosoma brucei THT1 - hexose transporter, putative 0.0064 0.067 0.8771
Brugia malayi hypothetical protein 0.0251 0.2808 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0201 0.2596
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0268 0.0955
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0012 0.0068 0.0243
Trichomonas vaginalis helicase, putative 0.0006 0.0009 0.0031
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0114 0.0125
Loa Loa (eye worm) hypothetical protein 0.0043 0.0433 0.1543
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0049 0.0176
Plasmodium vivax threonine--tRNA ligase, putative 0.0012 0.0068 0.0068
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0049 0.0054
Mycobacterium tuberculosis Conserved protein 0.0043 0.0433 0.1389
Onchocerca volvulus 0.0043 0.0433 0.1568
Loa Loa (eye worm) hypothetical protein 0.0063 0.0661 0.2353
Onchocerca volvulus 0.0029 0.0268 0.0971
Onchocerca volvulus 0.0029 0.0268 0.0971
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0072 0.0764 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0568 0.0622
Schistosoma mansoni cpg binding protein 0.003 0.0279 0.0342
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0464 0.0569
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0047 0.0168
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0148 0.0527
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0029 0.0035
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Giardia lamblia Asparaginyl-tRNA synthetase 0.0007 0.0015 0.0225
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0297 0.0448
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0007 0.0013 0.0014
Onchocerca volvulus 0.0043 0.0433 0.1568
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0009 0.0031
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0013 0.0042
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0176
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0049 0.0176
Brugia malayi Sugar transporter family protein 0.0029 0.0268 0.0955
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0046 0.0464 0.6074
Schistosoma mansoni glycyl-tRNA synthetase 0.0012 0.0068 0.0084
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Plasmodium falciparum calcium-dependent protein kinase 2 0.0063 0.0661 0.0661
Loa Loa (eye worm) hypothetical protein 0.0017 0.0134 0.0477
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0007 0.0015 0.019
Onchocerca volvulus 0.0023 0.0201 0.0728
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0012 0.0068 0.2114
Trypanosoma brucei asparaginyl-tRNA synthetase, putative 0.0007 0.0015 0.019
Toxoplasma gondii sugar transporter ST1 0.0029 0.0268 0.0404
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0217 0.242 0.8619
Entamoeba histolytica hypothetical protein 0.0073 0.0775 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0114 0.0404
Plasmodium falciparum lysine--tRNA ligase 0.0046 0.0464 0.0464
Loa Loa (eye worm) sugar transporter 0.0029 0.0268 0.0955
Loa Loa (eye worm) hypothetical protein 0.0048 0.0491 0.1747
Onchocerca volvulus 0.0029 0.0268 0.0971
Trypanosoma brucei glucose transporter, putative 0.0064 0.067 0.8771
Brugia malayi beta-lactamase family protein 0.0043 0.0433 0.1543
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0049 0.0054
Plasmodium falciparum threonine--tRNA ligase 0.0012 0.0068 0.0068
Echinococcus granulosus solute carrier family 22 0.0029 0.0268 0.0329
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0114 0.0404
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0464 1
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0015 0.0018
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0277 0.034
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0775 0.095
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0013 0.0046
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0337 0.4407
Schistosoma mansoni hypothetical protein 0.0073 0.0775 0.095
Giardia lamblia Lysyl-tRNA synthetase 0.0046 0.0464 0.7182
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0134 0.0429
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0013 0.0046
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0007 0.0015 0.019
Echinococcus multilocularis solute carrier family 22 0.0029 0.0268 0.0294
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0012 0.0068 0.0243
Schistosoma mansoni coup transcription factor 0.001 0.0049 0.0061
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0207 0.2306 0.2527
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0114 0.0125
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0012 0.0068 0.0075
Schistosoma mansoni protein kinase 0.0063 0.0661 0.0811
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0013 0.0046
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0009 0.0031
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0063 0.0661 0.0811
Giardia lamblia Sugar-proton symporter 0.0029 0.0268 0.415
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0063 0.0661 0.0724
Trypanosoma cruzi hexose transporter, putative 0.0064 0.067 0.8771
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Onchocerca volvulus 0.0032 0.0297 0.1076
Brugia malayi Sugar transporter family protein 0.0207 0.2306 0.8212
Mycobacterium leprae Probable lipase LipE 0.0043 0.0433 0.6704
Plasmodium vivax SET domain protein, putative 0.0032 0.0297 0.0297
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0433 0.1389
Giardia lamblia Threonyl-tRNA synthetase 0.0012 0.0068 0.1055
Trichomonas vaginalis glucose transporter, putative 0.0064 0.067 0.2426
Trypanosoma cruzi asparaginyl-tRNA synthetase, putative 0.0007 0.0015 0.019
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0049 0.0176
Onchocerca volvulus 0.0028 0.026 0.0942
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0049 0.0176
Onchocerca volvulus 0.0029 0.0268 0.0971
Trypanosoma cruzi sugar transporter, putative 0.0029 0.0268 0.351
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0062 0.0646 0.0793
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0207 0.2306 0.2829
Schistosoma mansoni hypothetical protein 0.0016 0.0114 0.0139
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.0068 0.0892
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0062 0.0646 0.2301
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0013 0.017
Onchocerca volvulus 0.0029 0.0268 0.0971
Echinococcus multilocularis survival motor neuron protein 1 0.0251 0.2808 0.3077
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0568 0.0697
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0029 0.0035
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0015 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0433 0.567
Leishmania major lysyl-tRNA synthetase, putative 0.0007 0.0015 0.019
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0394
Schistosoma mansoni hypothetical protein 0.0016 0.0114 0.0139
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0049 0.0176
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0207 0.2306 0.2829
Trypanosoma brucei glucose transporter, putative 0.0064 0.067 0.8771
Plasmodium vivax asparagine--tRNA ligase, putative 0.0007 0.0015 0.0015
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Mycobacterium tuberculosis Conserved hypothetical protein 0.001 0.0053 0.0169
Loa Loa (eye worm) hypothetical protein 0.0012 0.0068 0.0243
Loa Loa (eye worm) aspartyl-tRNA synthetase 0.0007 0.0015 0.0052
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.0007 0.0015 0.0018
Entamoeba histolytica aspartyl-tRNA synthetase, putative 0.0007 0.0015 0.0188
Brugia malayi Asparaginyl-tRNA synthetase, cytoplasmic 0.0007 0.0015 0.0052
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0009 0.0031
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0007 0.0013 0.002
Echinococcus multilocularis solute carrier family 22 0.0029 0.0268 0.0294
Loa Loa (eye worm) hypothetical protein 0.0046 0.0464 0.1653
Trypanosoma brucei histidyl-tRNA synthetase 0.0007 0.0015 0.0195
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0049 0.0176
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0114 0.0124
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0007 0.0013 0.0042
Trichomonas vaginalis aspartyl/lysyl-tRNA synthetase, putative 0.0007 0.0015 0.0053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0134 0.0477
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0176
Toxoplasma gondii facilitative glucose transporter GT1 0.0207 0.2306 0.3476
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.0068 0.1223
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0148 0.0162
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0007 0.0013 0.0201
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0297 0.0365
Toxoplasma gondii ABC1 family protein 0.0043 0.0433 0.0653
Echinococcus multilocularis microtubule associated protein 2 0.0717 0.8153 0.8932
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0013 0.0046
Leishmania major glucose transporter, lmgt2 0.0064 0.067 0.8771
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0207 0.2306 0.2527
Plasmodium falciparum histidine--tRNA ligase, putative 0.0007 0.0015 0.0015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0009 0.0031
Onchocerca volvulus 0.0029 0.0268 0.0971
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0521 0.1855
Giardia lamblia Glycyl-tRNA synthetase 0.0012 0.0068 0.1055
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Echinococcus granulosus FTZ F1 alpha 0.001 0.0049 0.0061
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0207 0.2306 0.2829
Plasmodium vivax lysine--tRNA ligase, putative 0.0046 0.0464 0.0464
Mycobacterium ulcerans hypothetical protein 0.001 0.0053 0.0879
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0114 0.149
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0007 0.0013 0.0168
Schistosoma mansoni survival motor neuron protein 0.0051 0.0521 0.0639
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0013 0.0016
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0049 0.0061
Plasmodium vivax aspartate--tRNA ligase, putative 0.0007 0.0015 0.0015
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0063 0.0661 0.0811
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0148 0.2992
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0568 0.0622
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0007 0.0015 0.0195
Onchocerca volvulus 0.0247 0.2763 1
Schistosoma mansoni sugar transporter 0.0029 0.0268 0.0329
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0433 0.9316
Trypanosoma brucei glucose transporter 2A 0.0064 0.067 0.8771
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0007 0.0013 0.0042
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0063 0.0661 0.0811
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0201 0.0716
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0201 0.3113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0049 0.0176
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0433 0.0531
Schistosoma mansoni protein kinase 0.0063 0.0661 0.0811
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0148 0.191
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0148 0.1936
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.0068 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0009 0.0031
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0072 0.0764 1
Onchocerca volvulus 0.0029 0.0268 0.0971
Plasmodium vivax histidine--tRNA ligase, putative 0.0007 0.0015 0.0015
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0049 0.0179
Schistosoma mansoni histidyl-tRNA synthetase 0.0007 0.0015 0.0018
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Entamoeba histolytica hypothetical protein 0.0073 0.0775 1
Leishmania major histidyl-tRNA synthetase, putative 0.0007 0.0015 0.0195
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0394
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0268 0.0955
Schistosoma mansoni sugar transporter 0.0029 0.0268 0.0329
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0007 0.0013 0.0013
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0063 0.0661 0.0724
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0433 0.1543
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Plasmodium vivax hexose transporter 0.0207 0.2306 0.2306
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0049 0.0061
Onchocerca volvulus 0.0029 0.0268 0.0971
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0009 0.0031
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0433 0.0433
Trypanosoma brucei THT1 - hexose transporter, putative 0.0064 0.067 0.8771
Trypanosoma brucei glucose transporter, putative 0.0064 0.067 0.8771
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0134 0.2654
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0297 0.0365
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0207 0.2306 0.2527
Giardia lamblia Aspartyl-tRNA synthetase 0.0007 0.0015 0.0225
Giardia lamblia Prolyl-tRNA synthetase 0.0062 0.0646 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0176
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0068 0.0892
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0029 0.0035
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0013 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0053 0.0191
Echinococcus granulosus histidyl tRNA synthetase 0.0007 0.0015 0.0018
Mycobacterium ulcerans hypothetical protein 0.0023 0.0201 0.4172
Schistosoma mansoni protein kinase 0.0063 0.0661 0.0811
Trypanosoma brucei glucose transporter, putative 0.0064 0.067 0.8771
Entamoeba histolytica protein kinase, putative 0.0063 0.0661 0.8529
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0049 0.0061
Leishmania major glucose transporter/membrane transporter D2, putative 0.0064 0.067 0.8771
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0029 0.0268 0.086
Loa Loa (eye worm) hypothetical protein 0.0023 0.0201 0.0716
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0072 0.0764 0.1152
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0297 0.0365
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0049 0.0176
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0046 0.0464 0.168
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0049 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0268 0.0971
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0007 0.0015 0.019
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0049 0.0176
Loa Loa (eye worm) hypothetical protein 0.0049 0.05 0.178
Loa Loa (eye worm) hypothetical protein 0.0043 0.0433 0.1543
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0009 0.0031
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0201 0.4172
Schistosoma mansoni sugar transporter 0.0029 0.0268 0.0329
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Schistosoma mansoni hypothetical protein 0.0016 0.0114 0.0139
Toxoplasma gondii sugar transporter ST3 0.0029 0.0268 0.0404
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.0068 0.1223
Toxoplasma gondii protein kinase, putative 0.0584 0.6635 1
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0007 0.0015 0.0053
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0433 0.1543
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0007 0.0013 0.0016
Mycobacterium ulcerans aspartyl-tRNA synthetase 0.0007 0.0015 0.0035
Onchocerca volvulus 0.0029 0.0268 0.0971
Mycobacterium tuberculosis Conserved protein 0.0043 0.0433 0.1389
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0007 0.0013 0.0042
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0029 0.0268 0.351
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0334 0.3767 0.3767
Echinococcus multilocularis asparaginyl tRNA synthetase 0.0007 0.0015 0.0016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0009 0.0031
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0063 0.0661 0.0997
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0114 0.0125
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0049 0.0053
Brugia malayi steroid hormone receptor 0.001 0.0049 0.0176
Schistosoma mansoni cpg binding protein 0.0028 0.026 0.0319
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.0007 0.0015 0.0018
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0114 0.0125
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0433 0.1389
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0207 0.2306 0.2527
Loa Loa (eye worm) hypothetical protein 0.0043 0.0433 0.1543
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.0068 0.0247
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0007 0.0013 0.0042
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0297 0.0326
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0007 0.0015 0.0042
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.026 0.0927
Brugia malayi hypothetical protein 0.0073 0.0775 0.2759
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0015 0.0018
Brugia malayi isocitrate dehydrogenase 0.0016 0.0114 0.0405
Schistosoma mansoni glucose transporter 0.0029 0.0268 0.0329
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0049 0.0176
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0201 0.2633
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0029 0.0268 0.086
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0049 0.0179
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0201 0.4172
Trypanosoma cruzi hexose transporter, putative 0.0064 0.067 0.8771
Echinococcus granulosus solute carrier family 22 0.0029 0.0268 0.0329
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0433 0.1389
Schistosoma mansoni hypothetical protein 0.0016 0.0114 0.0139
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0464 0.0569
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0063 0.0661 0.0997
Trypanosoma brucei glucose transporter, putative 0.0064 0.067 0.8771
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0068 0.0892
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0661 0.0811
Loa Loa (eye worm) histone methyltransferase 0.001 0.0049 0.0173
Entamoeba histolytica asparaginyl-tRNA synthetase, putative 0.0007 0.0015 0.0188
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0007 0.0013 0.0042
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.001 0.0053 0.0689
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.0661 0.2392
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0201 0.4172
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0046 0.0464 0.6074
Echinococcus granulosus solute carrier family 22 0.0029 0.0268 0.0329
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0049 0.0176
Leishmania major hypothetical protein, conserved 0.001 0.0053 0.0689
Leishmania major protein kinase, putative 0.0063 0.0661 0.865
Plasmodium falciparum calcium-dependent protein kinase 4 0.0063 0.0661 0.0661
Leishmania major aspartyl-tRNA synthetase, putative 0.0007 0.0015 0.019
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0007 0.0013 0.017
Brugia malayi hypothetical protein 0.0029 0.0268 0.0955
Brugia malayi major facilitator superfamily protein 0.0029 0.0268 0.0955
Mycobacterium ulcerans integral membrane transport protein 0.0029 0.0268 0.5658
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.0007 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0251 0.2808 1
Onchocerca volvulus Putative transporter 0.0029 0.0268 0.0971
Trichomonas vaginalis set domain proteins, putative 0.0247 0.2763 1
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0268 0.0955
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0049 0.0054
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0072 0.0764 1
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0063 0.0661 0.0661
Onchocerca volvulus 0.001 0.0049 0.0179
Echinococcus granulosus cpg binding protein 0.003 0.0279 0.0342
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0025 0.0227 0.0808
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0201 0.4172
Echinococcus multilocularis tumor protein p63 0.0331 0.3732 0.4089
Echinococcus granulosus calcium dependent protein kinase 0.0059 0.0616 0.0756
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0201 0.2596
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0013 0.0046
Onchocerca volvulus 0.0051 0.0521 0.1885
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0049 0.0176
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0201 0.4172
Schistosoma mansoni thyroid hormone receptor 0.001 0.0049 0.0061
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0433 0.1389
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0063 0.0661 0.0724
Trypanosoma cruzi hexose transporter, putative 0.0064 0.067 0.8771
Echinococcus granulosus tumor protein p63 0.0331 0.3732 0.4578
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0268 0.0971
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0007 0.0013 0.0201
Leishmania major hypothetical protein, conserved 0.0043 0.0433 0.567
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0114 0.0405
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0148 0.0536
Giardia lamblia Hexose transporter 0.0029 0.0268 0.415
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Trichomonas vaginalis sugar transporter, putative 0.0064 0.067 0.2426
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Trichomonas vaginalis conserved hypothetical protein 0.0207 0.2306 0.8348
Echinococcus granulosus survival motor neuron protein 1 0.0251 0.2808 0.3445
Echinococcus granulosus dnaJ subfamily B 0.0404 0.4572 0.5608
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0114 0.0365
Trichomonas vaginalis myo-inositol transporter, putative 0.0029 0.0268 0.0971
Brugia malayi glycyl-tRNA synthetase 0.0012 0.0068 0.0243
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0007 0.0015 0.0016
Echinococcus multilocularis solute carrier family 22 0.0029 0.0268 0.0294
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0148 0.0148
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0433 0.0531
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0049 0.0061
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0394
Brugia malayi hypothetical protein 0.0029 0.0268 0.0955
Plasmodium falciparum hexose transporter 0.0207 0.2306 0.2306
Loa Loa (eye worm) oxidoreductase 0.0007 0.0013 0.0046
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0433 0.1389
Echinococcus multilocularis solute carrier family 22 0.0029 0.0268 0.0294
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0201 0.2633
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0297 0.0365
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0053 0.0689
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0009 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0009 0.0031
Plasmodium falciparum mitogen-activated protein kinase 2 0.0334 0.3767 0.3767
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.0384 0.1232
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0012 0.0068 0.088
Chlamydia trachomatis histidine--tRNA ligase 0.0007 0.0015 0.0008
Trypanosoma brucei THT1 - hexose transporter, putative 0.0064 0.067 0.8771
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0007 0.0015 0.0054
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0176
Leishmania major aspartyl-tRNA synthetase, putative 0.0007 0.0015 0.019
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0176
Schistosoma mansoni nuclear hormone receptor 0.001 0.0049 0.0061
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0007 0.0013 0.017
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0063 0.0661 0.0997
Chlamydia trachomatis proline--tRNA ligase 0.0022 0.0186 0.3815
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0433 0.1568
Loa Loa (eye worm) hypothetical protein 0.0017 0.0134 0.0477
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0565 0.0851
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0568 0.0697
Brugia malayi beta-lactamase 0.0043 0.0433 0.1543
Mycobacterium leprae conserved hypothetical protein 0.001 0.0053 0.0815
Treponema pallidum threonyl-tRNA synthetase 0.0012 0.0068 0.3127
Brugia malayi CXXC zinc finger family protein 0.0028 0.026 0.0927
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0049 0.0061
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0012 0.0068 0.0243
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0201 0.3113
Brugia malayi ecdysteroid receptor 0.001 0.0049 0.0176
Schistosoma mansoni ap endonuclease 0.0019 0.0148 0.0181
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0007 0.0013 0.0201
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0201 0.0645
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Echinococcus granulosus General substrate transporter 0.0178 0.1973 0.242
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0062 0.0646 0.0793
Plasmodium vivax calcium-dependent protein kinase, putative 0.0063 0.0661 0.0661
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0015 0.0018
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0201 0.0716
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0049 0.0176
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0148 0.526
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Entamoeba histolytica protein kinase, putative 0.0063 0.0661 0.8529
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0062 0.0646 0.0793
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0148 0.0536
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0063 0.0661 0.2353
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0049 0.0176
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0201 0.0645
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0268 0.0955
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0049 0.0176
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0063 0.0661 0.865
Echinococcus multilocularis calcium dependent protein kinase 0.0059 0.0616 0.0675
Brugia malayi Aspartyl-tRNA synthetase 0.0007 0.0015 0.0052
Leishmania major threonyl-tRNA synthetase, putative 0.0012 0.0068 0.0892
Echinococcus multilocularis General substrate transporter 0.0178 0.1973 0.2161
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0049 0.0054
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0433 0.1568
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Plasmodium falciparum calcium-dependent protein kinase 3 0.0063 0.0661 0.0661
Entamoeba histolytica hypothetical protein 0.0073 0.0775 1
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0013 0.0047
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0433 0.1389
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0114 0.0404
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0007 0.0015 0.0022
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0568 0.2023
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0062 0.0646 0.2339
Schistosoma mansoni cpg binding protein 0.003 0.0279 0.0342
Loa Loa (eye worm) hypothetical protein 0.0062 0.0646 0.2301
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0114 0.014
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0029 0.0268 0.0294
Plasmodium vivax glycine--tRNA ligase, putative 0.0012 0.0068 0.0068
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0049 0.0176
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0009 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0053 0.0191
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0013 0.0042
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0394
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0201 0.4172
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0433 0.0475
Echinococcus granulosus solute carrier family 22 0.0029 0.0268 0.0329
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0114 0.149
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0049 0.0176
Onchocerca volvulus 0.0029 0.0268 0.0971
Onchocerca volvulus 0.0043 0.0433 0.1568
Plasmodium vivax sugar transporter, putative 0.0029 0.0268 0.0268
Onchocerca volvulus 0.0029 0.0268 0.0971
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0007 0.0015 0.0192
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Plasmodium vivax proline--tRNA ligase, putative 0.0072 0.0764 0.0764
Mycobacterium ulcerans hypothetical protein 0.0043 0.0433 0.9316
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0049 0.0176
Plasmodium falciparum calcium-dependent protein kinase 5 0.0063 0.0661 0.0661
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0433 0.567
Toxoplasma gondii aspartate-tRNA ligase 0.0007 0.0015 0.0022
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0114 0.0172
Echinococcus granulosus synaptic vesicle 2 protein 0.0029 0.0268 0.0329
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0201 0.2596
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0148 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0053 0.0191
Leishmania major hypothetical protein, conserved 0.0029 0.0268 0.351
Echinococcus granulosus lysyl tRNA synthetase 0.0046 0.0464 0.0569
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0148 0.0474
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0007 0.0015 0.0054
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.05 0.178
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0015 0.0018
Brugia malayi hypothetical protein 0.0029 0.0268 0.0955
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0049 0.0061
Onchocerca volvulus 0.0029 0.0268 0.0971
Loa Loa (eye worm) sugar transporter 0.0207 0.2306 0.8212
Schistosoma mansoni ap endonuclease 0.0019 0.0148 0.0181
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0063 0.0661 0.0811
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0012 0.0068 0.0243
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0072 0.0764 1
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0007 0.0015 0.019
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0049 0.0061
Schistosoma mansoni glucose transport protein 0.0207 0.2306 0.2829
Brugia malayi major facilitator superfamily protein 0.0029 0.0268 0.0955
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0053 0.0689
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0176
Treponema pallidum glycyl-tRNA synthetase 0.0007 0.0015 0.002
Onchocerca volvulus 0.0007 0.0013 0.0047
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Echinococcus granulosus Sugar transporter ERD6 protein 0.0029 0.0268 0.0329
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0114 0.0124
Onchocerca volvulus 0.0029 0.0268 0.0971
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0148 0.1936
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0007 0.0013 0.0042
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0006 0.0002 0.0007
Trichomonas vaginalis sugar transporter, putative 0.0064 0.067 0.2426
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0049 0.0061
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0062 0.0646 1
Echinococcus multilocularis cpg binding protein 0.003 0.0279 0.0306
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.001 0.0053 0.0689
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0009 0.0031
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0268 0.0955
Trichomonas vaginalis sugar transporter, putative 0.0064 0.067 0.2426
Echinococcus granulosus glycyl tRNA synthetase 0.0012 0.0068 0.0084
Brugia malayi lysyl-tRNA synthetase 0.0046 0.0464 0.1653
Schistosoma mansoni microtubule-associated protein tau 0.0717 0.8153 1
Entamoeba histolytica hypothetical protein 0.0073 0.0775 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0433 0.1389
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0049 0.0054
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.0007 0.0013 0.0046
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.001 0.0053 0.0689
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0007 0.0015 0.019
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0049 0.0176
Plasmodium falciparum glycine--tRNA ligase 0.0007 0.0015 0.0015
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0029 0.0268 0.0268
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0114 0.0139
Trypanosoma brucei glucose transporter, putative 0.0064 0.067 0.8771
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0013 0.017
Schistosoma mansoni histidyl-tRNA synthetase 0.0007 0.0015 0.0018
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0134 0.2679
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0568 0.0697
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0114 0.149
Echinococcus granulosus Threonyl tRNA synthetase C 0.0012 0.0068 0.0084
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0049 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0268 0.0971
Trichomonas vaginalis glucose transporter, putative 0.0064 0.067 0.2426
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0007 0.0015 0.019
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0114 0.0404
Echinococcus multilocularis histidyl tRNA synthetase 0.0007 0.0015 0.0016
Echinococcus granulosus microtubule associated protein 2 0.0717 0.8153 1
Trypanosoma brucei sugar transporter, putative 0.0029 0.0268 0.351
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0063 0.0661 0.0661
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0433 0.1568
Toxoplasma gondii anticodon binding domain-containing protein 0.0007 0.0015 0.0022
Plasmodium vivax asparagine--tRNA ligase, putative 0.0007 0.0015 0.0015
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0049 0.006
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0491 0.0602
Schistosoma mansoni hypothetical protein 0.0404 0.4572 0.5608
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0062 0.0646 0.0708
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Trichomonas vaginalis esterase, putative 0.0043 0.0433 0.1568
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0201 0.2633
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0029 0.0268 0.0329
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.0068 0.1055
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0029 0.0268 1
Schistosoma mansoni thyroid hormone receptor 0.001 0.0049 0.0061
Schistosoma mansoni sugar transporter 0.0029 0.0268 0.0329
Loa Loa (eye worm) hypothetical protein 0.0043 0.0433 0.1543
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0049 0.0179
Loa Loa (eye worm) hypothetical protein 0.0023 0.0201 0.0716
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0013 0.0042
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0114 0.149
Mycobacterium ulcerans beta-lactamase 0.0043 0.0433 0.9316
Leishmania major lysyl-tRNA synthetase, putative 0.0046 0.0464 0.6074
Brugia malayi nuclear receptor NHR-88 0.001 0.0049 0.0176
Trypanosoma cruzi hexose transporter 0.0064 0.067 0.8771
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0268 0.351
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0049 0.0176
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0433 0.0531
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0568 0.0697
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0433 0.1568
Echinococcus granulosus geminin 0.0168 0.1856 0.2276
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0007 0.0015 0.019
Toxoplasma gondii lysine-tRNA ligase 0.0046 0.0464 0.0699
Loa Loa (eye worm) hypothetical protein 0.0017 0.0134 0.0477
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0638 0.0783
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0201 0.0716
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0007 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0039 0.0384 0.1232
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0009 0.0031
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0013 0.0047
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0433 0.9316
Onchocerca volvulus 0.0007 0.0013 0.0047
Trypanosoma cruzi glucose transporter, putative 0.0029 0.0268 0.351
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0433 0.1568
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0046 0.0464 0.7182
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0029 0.0031
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0007 0.0015 0.0016
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0148 0.1936
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0022 0.0186 0.3837
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0148 0.7779
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0049 0.0061
Leishmania major glycyl tRNA synthetase, putative 0.0007 0.0015 0.0195
Plasmodium falciparum asparagine--tRNA ligase 0.0007 0.0015 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0013 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0009 0.0031
Brugia malayi Cam kinase protein 1 0.0063 0.0661 0.2353
Loa Loa (eye worm) hypothetical protein 0.0043 0.0433 0.1543
Entamoeba histolytica hypothetical protein 0.0046 0.0464 0.5989
Leishmania major hypothetical protein, conserved 0.001 0.0053 0.0689
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0268 0.0971
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.067 0.2426
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0049 0.0061
Echinococcus multilocularis synaptic vesicle 2 protein 0.0029 0.0268 0.0294
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Loa Loa (eye worm) hypothetical protein 0.0007 0.0013 0.0046
Plasmodium falciparum aspartate--tRNA ligase 0.0007 0.0015 0.0015
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0013 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0009 0.0031
Trypanosoma brucei glucose transporter, putative 0.0064 0.067 0.8771
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0009 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0049 0.0176
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0012 0.0068 0.088
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0321 0.1143
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0464 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0049 0.0176
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.3119 1
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0268 0.0971
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0268 0.0971
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.05 0.178
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0148 0.0527
Loa Loa (eye worm) beta-lactamase 0.0043 0.0433 0.1543
Mycobacterium ulcerans lipase LipD 0.0043 0.0433 0.9316
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0268 0.0404
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0114 0.0172
Schistosoma mansoni threonyl-tRNA synthetase 0.0007 0.0015 0.0018
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0568 0.0697
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0134 0.0134
Plasmodium vivax acetyl-CoA synthetase, putative 0.0007 0.0013 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0297 0.0365
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0015 0.0018
Leishmania major myo-inositol/proton symporter (MIT) 0.0029 0.0268 0.351
Onchocerca volvulus 0.0029 0.0268 0.0971
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0114 0.0139
Loa Loa (eye worm) hypothetical protein 0.0032 0.0297 0.1059
Loa Loa (eye worm) hypothetical protein 0.0029 0.0268 0.0955
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0114 0.0114
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0062 0.0646 0.834
Brugia malayi nuclear hormone receptor 0.001 0.0049 0.0176
Loa Loa (eye worm) hypothetical protein 0.0023 0.0201 0.0716
Echinococcus multilocularis lysyl tRNA synthetase 0.0046 0.0464 0.0508
Plasmodium vivax CDK-related protein kinase 6, putative 0.0878 1 1
Echinococcus granulosus GPCR family 2 0.0016 0.0114 0.0139
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0029 0.0268 0.5658
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.0384 0.5947
Treponema pallidum prolyl-tRNA synthetase 0.0022 0.0186 1
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0334 0.3767 0.5677
Mycobacterium tuberculosis Conserved protein 0.0043 0.0433 0.1389
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0049 0.0061
Schistosoma mansoni glucose transport protein 0.0207 0.2306 0.2829

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 3.9811 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 5.0119 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 70.7946 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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