Detailed information for compound 739297

Basic information

Technical information
  • TDR Targets ID: 739297
  • Name: N-(2-morpholin-4-ylethyl)-4-propan-2-yloxyben zamide
  • MW: 292.373 | Formula: C16H24N2O3
  • H donors: 1 H acceptors: 1 LogP: 1.63 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(Oc1ccc(cc1)C(=O)NCCN1CCOCC1)C
  • InChi: 1S/C16H24N2O3/c1-13(2)21-15-5-3-14(4-6-15)16(19)17-7-8-18-9-11-20-12-10-18/h3-6,13H,7-12H2,1-2H3,(H,17,19)
  • InChiKey: JTQPRXTUSOXIFZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-isopropoxy-N-(2-morpholinoethyl)benzamide
  • N-(2-morpholin-4-ylethyl)-4-propan-2-yloxy-benzamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0015 0.0297
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0039
Echinococcus multilocularis importin subunit beta 1 0.0028 0.003 0.025
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0013 0.0215
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0049 0.0049
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0015 0.0127
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0075 0.0113 0.2172
Schistosoma mansoni zinc finger protein 0.0023 0.0021 0.017
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.00000046262 0.0000038287
Leishmania major telomerase reverse transcriptase, putative 0.1541 0.2717 1
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0057
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0013 0.0039
Loa Loa (eye worm) hypothetical protein 0.0031 0.0034 0.0659
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0013 0.0105
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0065 0.0065
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0044 0.0361
Plasmodium vivax calpain, putative 0.0019 0.0014 0.0051
Brugia malayi Pre-SET motif family protein 0.0031 0.0034 0.0047
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0297
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0075 0.0113 0.0391
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0015 0.0127
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0189 0.3639
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0015 0.0297
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0065 0.0535
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.05 1
Echinococcus granulosus calpain A 0.0068 0.01 0.083
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.00000046262 0.00000786
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0029 0.0579
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0025
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0065 0.0535
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0013 0.0229
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0005 0.0106
Plasmodium vivax hypothetical protein, conserved 0.0011 0.00000046262 0.0000017029
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0013 0.0112
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.007 0.0235
Entamoeba histolytica hypothetical protein 0.0035 0.0043 0.0726
Echinococcus multilocularis chromobox protein 1 0.007 0.0104 0.0859
Echinococcus multilocularis dnaJ subfamily B 0.0403 0.0696 0.5761
Echinococcus granulosus zinc finger protein 0.0023 0.0021 0.017
Echinococcus granulosus tar DNA binding protein 0.0097 0.0151 0.1253
Schistosoma mansoni chromobox protein 0.007 0.0104 0.0859
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0015 0.0015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0011 0.0228
Brugia malayi nuclear receptor NHR-88 0.002 0.0015 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0015 0.0021
Brugia malayi calpain 7 0.0019 0.0014 0.0019
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0071 0.059
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0015 0.0127
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0034 0.0281
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0015 0.0127
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0017 0.0024
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0014 0.004
Onchocerca volvulus 0.0061 0.0089 0.0089
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0045 0.0143
Schistosoma mansoni flap endonuclease-1 0.0023 0.0021 0.0173
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0298 0.0509 0.1863
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0015 0.0127
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0015 0.0021
Onchocerca volvulus 0.0238 0.0403 0.0403
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0007 0.0142
Schistosoma mansoni tar DNA-binding protein 0.0097 0.0151 0.1253
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0015 0.0021
Onchocerca volvulus 0.0048 0.0065 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0039
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0092 0.0761
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0007 0.0061
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0297
Brugia malayi mbt repeat family protein 0.0048 0.0065 0.0089
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0013 0.0112
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0298 0.0509 0.1852
Echinococcus granulosus dnaJ subfamily B 0.0403 0.0696 0.5761
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0061 0.1178
Schistosoma mansoni chromobox protein 0.007 0.0104 0.0859
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0071 0.1425
Trichomonas vaginalis chromobox protein, putative 0.007 0.0104 0.2075
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.05 1
Loa Loa (eye worm) inositol-1 0.0037 0.0045 0.0876
Echinococcus multilocularis calpain 7 (C02 family) 0.0019 0.0014 0.0114
Onchocerca volvulus Alhambra homolog 0.0029 0.0032 0.0032
Echinococcus multilocularis snurportin 1 0.0304 0.0519 0.4294
Brugia malayi ecdysteroid receptor 0.002 0.0015 0.0021
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0068 0.01 0.083
Echinococcus granulosus disco interacting protein 2 0.0038 0.0047 0.039
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.001 0.0083
Plasmodium vivax telomerase reverse transcriptase, putative 0.1541 0.2717 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0039
Giardia lamblia PHD finger protein 15 0.0029 0.0032 0.007
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.015 0.1239
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.00000046262 0.0000038287
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0014 0.0026
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0032 0.0262
Echinococcus granulosus importin subunit beta 1 0.0028 0.003 0.025
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0071 0.1425
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0014 0.004
Mycobacterium tuberculosis Conserved hypothetical protein 0.0157 0.0258 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0013 0.0039
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0071 0.1425
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0084 0.031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0015 0.0297
Schistosoma mansoni hypothetical protein 0.0029 0.0032 0.0262
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0014 0.0026
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0045 0.0909
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0293 0.05 0.8496
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0011 0.0228
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0014 0.0005 0.002
Brugia malayi TAR-binding protein 0.0097 0.0151 0.0208
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0038 0.0047 0.039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0015 0.0297
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0015 0.0021
Schistosoma mansoni hypothetical protein 0.0294 0.0503 0.416
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0055 0.109
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.00000046262 0.0000017029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0015 0.0297
Schistosoma mansoni ap endonuclease 0.0019 0.0013 0.0105
Echinococcus granulosus histone lysine methyltransferase setb 0.0048 0.0064 0.0532
Loa Loa (eye worm) hypothetical protein 0.0297 0.0507 0.9777
Schistosoma mansoni jun-related protein 0.007 0.0104 0.086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0015 0.0297
Brugia malayi BRM protein 0.0069 0.0102 0.014
Loa Loa (eye worm) hypothetical protein 0.0048 0.0065 0.1246
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0076 0.0632
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0014 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0049 0.0984
Schistosoma mansoni thyroid hormone receptor 0.002 0.0015 0.0127
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0023 0.0188
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0019 0.0014 0.0118
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0006 0.0122
Echinococcus multilocularis hypothetical protein 0.0019 0.0014 0.0114
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0297
Schistosoma mansoni hypothetical protein 0.0015 0.0007 0.0057
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0068 0.0094
Trichomonas vaginalis set domain proteins, putative 0.0238 0.0403 0.805
Brugia malayi PHD-finger family protein 0.0013 0.0003 0.0004
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0104 0.1999
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0061 0.0506
Schistosoma mansoni hypothetical protein 0.0167 0.0276 0.2288
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0034 0.0125
Echinococcus multilocularis dna polymerase eta 0.0019 0.0013 0.0112
Brugia malayi SET domain containing protein 0.0013 0.0003 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0015 0.0021
Brugia malayi nuclear hormone receptor 0.002 0.0015 0.0021
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.015 0.1239
Brugia malayi MH2 domain containing protein 0.0118 0.0189 0.026
Echinococcus granulosus muscleblind protein 0.0297 0.0507 0.4198
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0092 0.0761
Schistosoma mansoni hypothetical protein 0.0167 0.0276 0.2288
Plasmodium falciparum ataxin-2 like protein, putative 0.0015 0.0007 0.0025
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0019 0.0014 0.0243
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0014 0.0026
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.0003 0.0023
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0071 0.059
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0054 0.0188
Leishmania major mitochondrial DNA polymerase beta 0.0298 0.0509 0.1852
Schistosoma mansoni ap endonuclease 0.0019 0.0013 0.0105
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0049 0.0404
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0006 0.0052
Echinococcus multilocularis geminin 0.0167 0.0276 0.2288
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0011 0.0228
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0013 0.0035
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0015 0.0021
Brugia malayi chromobox protein homolog 3 0.0039 0.0049 0.0068
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0013 0.021
Schistosoma mansoni microtubule-associated protein tau 0.0692 0.1208 1
Trypanosoma cruzi kinesin, putative 0.0019 0.0014 0.0026
Echinococcus multilocularis calpain A 0.0068 0.01 0.083
Brugia malayi Bromodomain containing protein 0.0079 0.0119 0.0164
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0032 0.0262
Entamoeba histolytica hypothetical protein 0.0035 0.0043 0.0726
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0098 0.0153 0.2598
Brugia malayi RNA binding protein 0.0097 0.0151 0.0208
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0076 0.0632
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0011 0.0228
Giardia lamblia DINP protein human, muc B family 0.0019 0.0013 0.0003
Onchocerca volvulus 0.0011 0.0000000022261 0.0000000022261
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.0609
Entamoeba histolytica hypothetical protein 0.0011 0.0000000000071565 0.00000000012159
Schistosoma mansoni cpg binding protein 0.0065 0.0095 0.0786
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0054 0.0175
Schistosoma mansoni thyroid hormone receptor 0.002 0.0015 0.0127
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0071 0.059
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0343 0.0589 1
Toxoplasma gondii hypothetical protein 0.0048 0.0065 0.0239
Echinococcus multilocularis GPCR, family 2 0.0016 0.0008 0.0064
Schistosoma mansoni importin beta-1 0.0028 0.003 0.025
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0192 0.0321 0.2657
Trichomonas vaginalis STE family protein kinase 0.0075 0.0113 0.2254
Trypanosoma brucei antigen, putative 0.0019 0.0014 0.004
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0013 0.0019
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0014 0.004
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0083 0.0128 0.0471
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0025 0.043
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0007 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0011 0.0228
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0061 0.0506
Echinococcus multilocularis microtubule associated protein 2 0.0692 0.1208 1
Echinococcus granulosus jun protein 0.0086 0.0133 0.1097
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.00000046262 0.00000786
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0061 0.0084
Echinococcus multilocularis tar DNA binding protein 0.0097 0.0151 0.1253
Loa Loa (eye worm) glutaminase 2 0.027 0.0458 0.8837
Entamoeba histolytica calpain large subunit domain III containing protein 0.0019 0.0014 0.0235
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0068 0.01 0.083
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0014 0.0026
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0013 0.026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0015 0.0297
Schistosoma mansoni tar DNA-binding protein 0.0097 0.0151 0.1253
Plasmodium vivax ataxin-2 like protein, putative 0.0015 0.0007 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0029 0.0579
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.00000046262 0.0000017029
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0189 0.3639
Onchocerca volvulus 0.0045 0.006 0.006
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0052 0.043
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0034 0.0281
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0015 0.0127
Schistosoma mansoni helicase 0.0069 0.0102 0.084
Mycobacterium ulcerans hypothetical protein 0.0157 0.0258 0.5511
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0013 0.0022
Giardia lamblia DNA repair protein RAD52 0.0343 0.0589 0.213
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0065 0.0535
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0087 0.1674
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0014 0.0026
Echinococcus granulosus geminin 0.0167 0.0276 0.2288
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0045 0.0909
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0086 0.0133 0.1097
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0071 0.059
Trichomonas vaginalis glutaminase, putative 0.027 0.0458 0.9169
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0015 0.0127
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0097 0.0151 0.2918
Echinococcus multilocularis dual specificity mitogen activated protein 0.0075 0.0113 0.0933
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0065 0.0535
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0014 0.0026
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0043 0.0353
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0293 0.05 0.8496
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0015 0.0127
Toxoplasma gondii RNA-directed DNA polymerase 0.1541 0.2717 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0015 0.0021
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0014 0.0026
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0007 0.001
Loa Loa (eye worm) RNA binding protein 0.0097 0.0151 0.2918
Schistosoma mansoni tar DNA-binding protein 0.0097 0.0151 0.1253
Echinococcus granulosus GPCR family 2 0.0016 0.0008 0.0064
Toxoplasma gondii LsmAD domain-containing protein 0.0015 0.0007 0.0025
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0015 0.0127
Trichomonas vaginalis lymphoid specific helicase, putative 0.0014 0.0005 0.0107
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0071 0.0238
Leishmania major kinesin, putative 0.0019 0.0014 0.0026
Brugia malayi hypothetical protein 0.0035 0.0043 0.0059
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0008 0.0064
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0015 0.0127
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0068 0.01 0.083
Echinococcus multilocularis cpg binding protein 0.0065 0.0095 0.0786
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0039
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0297
Loa Loa (eye worm) MBCTL1 0.0054 0.0076 0.1472
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0044 0.0361
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.026
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0065 0.1246
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0065 0.0094 0.0781
Plasmodium falciparum ataxin-2 like protein, putative 0.0015 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0297
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0019 0.0014 0.0053
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0032 0.0262
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0064 0.0532
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0192 0.0321 0.2657
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0015 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0039
Trypanosoma cruzi kinesin, putative 0.0019 0.0014 0.0026
Schistosoma mansoni tar DNA-binding protein 0.0097 0.0151 0.1253
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0015 0.0021
Loa Loa (eye worm) BRM protein 0.0042 0.0055 0.1057
Brugia malayi RNA recognition motif domain containing protein 0.0097 0.0151 0.0208
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0021 0.0413
Brugia malayi Bromodomain containing protein 0.004 0.0051 0.007
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0115 0.095
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0016 0.0317
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0061 0.0506
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0015 0.0297
Echinococcus multilocularis chromobox protein 1 0.007 0.0104 0.0859
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0778
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0007 0.0002
Loa Loa (eye worm) hypothetical protein 0.0297 0.0507 0.9777
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0071 0.1373
Plasmodium falciparum phd finger protein, putative 0.0029 0.0032 0.0116
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0013 0.0244
Loa Loa (eye worm) hypothetical protein 0.0039 0.0049 0.0949
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0039
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0008 0.0011
Brugia malayi Pre-SET motif family protein 0.0209 0.0351 0.0484
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0019 0.0014 0.004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.05 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0048 0.0064 0.0532
Brugia malayi bZIP transcription factor family protein 0.0086 0.0133 0.0182
Loa Loa (eye worm) TAR-binding protein 0.0097 0.0151 0.2918
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0065 0.0535
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0045 0.0376
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0021 0.0051
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0071 0.0251
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0025 0.0093
Schistosoma mansoni Mername-AA248 (C02 family) 0.0019 0.0014 0.0114
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0007 0.0061
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0014 0.0026
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.2036
Giardia lamblia Fructose-bisphosphate aldolase 0.0293 0.05 0.1803
Loa Loa (eye worm) hypothetical protein 0.0048 0.0064 0.1239
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0015 0.0127
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0013 0.0022
Entamoeba histolytica hypothetical protein 0.0035 0.0043 0.0726
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0013 0.0022
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0071 0.1425
Leishmania major modification methylase-like protein 0.0019 0.0014 0.0028
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0007 0.0061
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0209 0.0351 0.6772
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.023 0.0824
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0039
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0013 0.0019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0025
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0008 0.0011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.05 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0039
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0006 0.0052
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0025 0.0093
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0015 0.0127
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0089 0.1709
Loa Loa (eye worm) helicase 0.0011 0.00000046261 0.0000089165
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.001 0.0083
Brugia malayi Flap endonuclease-1 0.0026 0.0025 0.0035
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0013 0.0253
Brugia malayi CHD4 protein 0.0015 0.0006 0.0009
Echinococcus multilocularis zinc finger protein 0.0023 0.0021 0.017
Echinococcus granulosus FTZ F1 alpha 0.002 0.0015 0.0127
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0045 0.0736
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.00000046262 0.00000786
Schistosoma mansoni glutaminase 0.027 0.0458 0.3794
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0039 0.1243
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0015 0.0127
Brugia malayi Disco-interacting protein 2 homolog 0.0038 0.0047 0.0065
Toxoplasma gondii DNA methyltransferase 2, putative 0.0019 0.0014 0.0053
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.00000046262 0.00000063695
Schistosoma mansoni protein kinase 0.0075 0.0113 0.0933
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0011 0.0228
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0065 0.0535
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0015 0.0127
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0019 0.0014 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0015 0.0021
Brugia malayi jmjC domain containing protein 0.0039 0.0049 0.0067
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0045 0.0167
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0032 0.0116
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0045 0.0909
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0039
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0071 0.0217
Schistosoma mansoni DNA polymerase eta 0.0019 0.0013 0.0112
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0015 0.0127
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0015 0.0127
Brugia malayi mbt repeat family protein 0.0048 0.0065 0.0089
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0045 0.0143
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0015 0.0127
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.003 0.0111
Brugia malayi CXXC zinc finger family protein 0.0061 0.0089 0.0122
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0071 0.0238
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0014 0.004
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0076 0.0632
Schistosoma mansoni bromodomain containing protein 0.0067 0.0098 0.0814
Loa Loa (eye worm) calpain family protein 1 0.0045 0.006 0.1162
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0068 0.01 0.083
Loa Loa (eye worm) calpain 5 0.0019 0.0014 0.0266
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0013 0.0244
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0013 0.0047
Brugia malayi PHD-finger family protein 0.0029 0.0032 0.0044
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0023 0.0188
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0582
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0298 0.0509 0.1852
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0061 0.0506
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0049 0.0984
Echinococcus granulosus global transcription activator snf2l2 0.0069 0.0102 0.084
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0045 0.0143
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0013 0.0039
Brugia malayi jmjC domain containing protein 0.0096 0.015 0.0206
Echinococcus granulosus microtubule associated protein 2 0.0692 0.1208 1
Trichomonas vaginalis STE family protein kinase 0.0075 0.0113 0.2254
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0064
Brugia malayi hypothetical protein 0.0015 0.0007 0.0009
Treponema pallidum fructose-bisphosphate aldolase 0.0293 0.05 1
Schistosoma mansoni hypothetical protein 0.0021 0.0016 0.0136
Plasmodium falciparum flap endonuclease 1 0.0026 0.0025 0.0093
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0015 0.0127
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0021 0.0413
Echinococcus granulosus calpain A 0.0019 0.0014 0.0114
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0064
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.023 0.0824
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0064
Brugia malayi steroid hormone receptor 0.002 0.0015 0.0021
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0015 0.0015
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0013 0.0047
Loa Loa (eye worm) hypothetical protein 0.0065 0.0094 0.1819
Entamoeba histolytica hypothetical protein 0.0035 0.0043 0.0726
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0068 0.0094
Loa Loa (eye worm) hypothetical protein 0.0065 0.0094 0.1819
Trypanosoma cruzi ISWI complex protein 0.0015 0.0007 0.0001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0055 0.1067
Trypanosoma cruzi ISWI complex protein 0.0015 0.0007 0.0001
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0013 0.0039
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.0003 0.0023
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0013 0.0019
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0021 0.0413
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0008 0.015
Plasmodium vivax SET domain protein, putative 0.0031 0.0034 0.0125
Mycobacterium ulcerans glutaminase 0.027 0.0458 1
Echinococcus multilocularis muscleblind protein 0.0297 0.0507 0.4198
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.2474
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0015 0.0021
Echinococcus granulosus dual specificity mitogen activated protein 0.0075 0.0113 0.0933
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.1541 0.2717 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0015 0.0127
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0015 0.0127
Schistosoma mansoni cpg binding protein 0.0061 0.0089 0.0734
Echinococcus granulosus chromobox protein 1 0.007 0.0104 0.0859
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0013 0.0244
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0013 0.0025
Loa Loa (eye worm) glutaminase 0.027 0.0458 0.8837
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0013 0.0025
Loa Loa (eye worm) BRM protein 0.0037 0.0045 0.0862
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0086 0.0133 0.1097
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.003 0.01
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0019 0.0014 0.0042
Trypanosoma brucei protein kinase, putative 0.0052 0.0071 0.0251
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0007 0.0027
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0008 0.0064
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0076 0.0632
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.0351
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0075 0.0113 0.0155
Schistosoma mansoni calpain-7 (C02 family) 0.0019 0.0014 0.0114
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0013 0.0112
Leishmania major DNA polymerase kappa, putative 0.0019 0.0013 0.0025
Echinococcus granulosus peregrin 0.0033 0.0039 0.0322
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0049 0.094
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0025 0.0082
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0007 0.0027
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0007 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0297
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0007 0.0016
Leishmania major importin beta-1 subunit, putative 0.0023 0.0021 0.0051
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0043 0.0353
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0007 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0015 0.0021
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0032 0.0116
Brugia malayi isocitrate dehydrogenase 0.0016 0.0007 0.001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0014 0.004
Trypanosoma brucei unspecified product 0.0019 0.0013 0.0039
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0032 0.0116
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0014 0.0026
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0013 0.0017
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0015 0.0127
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0023 0.0188
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0013 0.0105
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.00000046262 0.0000092515
Toxoplasma gondii hypothetical protein 0.0083 0.0128 0.0471
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0015 0.0127
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0011 0.0228
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0008 0.0064
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0076 0.0105
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0011 0.0092
Loa Loa (eye worm) hypothetical protein 0.005 0.0069 0.1324
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0007 0.0061
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0065 0.0535
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0000000022261 0.000000018424
Leishmania major hypothetical protein, conserved 0.0015 0.0007 0.0001
Schistosoma mansoni hypothetical protein 0.0304 0.0519 0.4294
Echinococcus granulosus dna polymerase kappa 0.0019 0.0013 0.0112
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0032 0.0609
Brugia malayi MAP kinase sur-1 0.0052 0.0071 0.0098
Onchocerca volvulus 0.0042 0.0054 0.0054
Brugia malayi Associated with TFs and helicases family protein 0.0023 0.002 0.0028
Echinococcus granulosus calpain 0.0019 0.0014 0.0114
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0007 0.0061
Brugia malayi Inositol-1 0.0037 0.0045 0.0063
Brugia malayi PHD-finger family protein 0.0028 0.003 0.0041
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0019 0.0014 0.0053
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0013 0.027
Brugia malayi hypothetical protein 0.0068 0.01 0.0137
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0054 0.0175
Plasmodium falciparum telomerase reverse transcriptase 0.1541 0.2717 1
Brugia malayi Bromodomain containing protein 0.0033 0.0039 0.0054
Brugia malayi Heterochromatin protein 1 0.007 0.0104 0.0143
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0025 0.0506
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.00000046262 0.0000092515
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.013
Brugia malayi calpain family protein 1 0.0065 0.0094 0.013
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0015 0.0021
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.0234 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0055 0.0055
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0025 0.0047
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0006 0.0121
Plasmodium vivax importin-beta 2, putative 0.0028 0.003 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0071 0.059
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.1319
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0071 0.0238
Echinococcus multilocularis calpain family protein 1, d 0.0045 0.006 0.0499
Trypanosoma brucei telomerase reverse transcriptase 0.1541 0.2717 1
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0013 0.0253
Schistosoma mansoni coup transcription factor 0.002 0.0015 0.0127
Echinococcus granulosus Chromobox protein 3 0.0011 0.0000000022261 0.000000018424
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.015
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0031 0.0256
Brugia malayi Importin beta-1 subunit 0.0028 0.003 0.0042
Trypanosoma brucei ISWI complex protein 0.0015 0.0007 0.0014
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0076 0.0632
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0049 0.0404
Schistosoma mansoni nuclear hormone receptor 0.002 0.0015 0.0127
Echinococcus multilocularis calpain 5 0.0019 0.0014 0.0114
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0297
Brugia malayi glutaminase DH11.1 0.027 0.0458 0.0631
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.0234 0.9027
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0054 0.0175
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0297
Loa Loa (eye worm) hypothetical protein 0.0038 0.0048 0.0925
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0014 0.0026
Schistosoma mansoni hypothetical protein 0.0015 0.0006 0.0052
Trypanosoma brucei PAB1-binding protein , putative 0.0015 0.0007 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0097 0.0151 0.1253
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0015 0.0021
Plasmodium falciparum importin beta, putative 0.0028 0.003 0.0111
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.00000046262 0.0000038287
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0006 0.0052
Schistosoma mansoni hypothetical protein 0.0034 0.004 0.0334
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.1541 0.2717 1
Echinococcus multilocularis Chromo domain 0.0023 0.002 0.0169
Echinococcus granulosus DNA methyltransferase 2, putative 0.0019 0.0014 0.0118
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0015 0.0127
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.00000046262 0.0000092515
Echinococcus granulosus cpg binding protein 0.0065 0.0095 0.0786
Echinococcus multilocularis muscleblind protein 1 0.0297 0.0507 0.4198
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0011 0.0228
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.003 0.01
Echinococcus multilocularis calpain 0.0019 0.0014 0.0114
Schistosoma mansoni zinc finger protein 0.0015 0.0007 0.0057
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0071 0.0262
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0014 0.0275
Schistosoma mansoni hypothetical protein 0.0035 0.0043 0.0353
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.0519 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0013 0.0112
Echinococcus multilocularis disco interacting protein 2 0.0038 0.0047 0.039
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0071 0.0238
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0043 0.0352
Trichomonas vaginalis STE family protein kinase 0.0075 0.0113 0.2254
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0015 0.0127
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0064 0.0532
Echinococcus multilocularis peregrin 0.0033 0.0039 0.0322
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0014 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0015 0.0021
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0071 0.0238
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0075 0.0113 0.0391
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0015 0.0127
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.0054 0.0449
Echinococcus granulosus calpain 7 C02 family 0.0019 0.0014 0.0114
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0088 0.0731
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0019 0.0014 0.0053
Schistosoma mansoni hypothetical protein 0.007 0.0104 0.086
Schistosoma mansoni calpain C (C02 family) 0.0019 0.0014 0.0114
Onchocerca volvulus 0.0038 0.0047 0.0047
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0043 0.0353
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0025 0.0069
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0055 0.109
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.001 0.0083
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0013 0.0112
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.05 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0045 0.0772
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0013 0.027
Brugia malayi Telomerase reverse transcriptase 0.41 0.7263 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0008 0.0064
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0061 0.0506
Echinococcus granulosus flap endonuclease 1 0.0026 0.0025 0.0209
Giardia lamblia Telomerase catalytic subunit 0.1541 0.2717 1
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.004 0.0056
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0007 0.0061
Brugia malayi calpain 5 0.0019 0.0014 0.0019
Loa Loa (eye worm) hypothetical protein 0.0011 0.00000046262 0.0000089166
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0052 0.043
Trypanosoma brucei kinesin, putative 0.0019 0.0014 0.004
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0071 0.0238
Entamoeba histolytica protein kinase, putative 0.002 0.0015 0.0263
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0015 0.0015
Schistosoma mansoni calpain-7 (C02 family) 0.0019 0.0014 0.0114
Loa Loa (eye worm) calpain family protein 1 0.0065 0.0094 0.1819
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0049 0.0404
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0025 0.0488
Loa Loa (eye worm) hypothetical protein 0.0038 0.0047 0.0909
Schistosoma mansoni cpg binding protein 0.0065 0.0095 0.0786
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0007 0.0002
Brugia malayi calpain family protein 1 0.0065 0.0094 0.013
Loa Loa (eye worm) helicase DNA-binding protein 0.0011 0.0000056683 0.0001
Echinococcus granulosus snurportin 1 0.0304 0.0519 0.4294
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0064
Echinococcus multilocularis global transcription activator snf2l2 0.0069 0.0102 0.084
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0013 0.0019
Brugia malayi Muscleblind-like protein 0.0297 0.0507 0.0698
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0025 0.0209
Schistosoma mansoni calpain (C02 family) 0.0019 0.0014 0.0114
Loa Loa (eye worm) hypothetical protein 0.0045 0.006 0.1162
Toxoplasma gondii exonuclease III APE 0.0019 0.0013 0.0047
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.001 0.0083
Onchocerca volvulus 0.002 0.0015 0.0015
Trichomonas vaginalis chromobox protein, putative 0.007 0.0104 0.2075
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0045 0.0376
Echinococcus granulosus dna polymerase eta 0.0019 0.0013 0.0112
Echinococcus granulosus calpain 5 0.0019 0.0014 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0061 0.0506
Schistosoma mansoni inositol monophosphatase 0.0037 0.0045 0.0376
Schistosoma mansoni hypothetical protein 0.0023 0.002 0.0169
Onchocerca volvulus 0.0031 0.0034 0.0034
Leishmania major DNA polymerase eta, putative 0.0019 0.0013 0.0025
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0141 0.023 0.0837
Echinococcus granulosus Chromo domain 0.0023 0.002 0.0169
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.05 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0045 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0068 0.1319
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0075 0.0113 0.0404
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.0234 0.4963
Brugia malayi RNA, U transporter 1 0.0081 0.0123 0.017
Entamoeba histolytica hypothetical protein 0.0098 0.0153 0.2598
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0006 0.0122
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.05 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0076 0.1472
Echinococcus multilocularis jun protein 0.0086 0.0133 0.1097
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0061 0.0506
Loa Loa (eye worm) hypothetical protein 0.0045 0.006 0.1162
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0045 0.0156
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0007 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0015 0.0021
Schistosoma mansoni inositol monophosphatase 0.0037 0.0045 0.0376
Onchocerca volvulus 0.0068 0.01 0.01
Echinococcus granulosus chromobox protein 1 0.007 0.0104 0.0859
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0015 0.0127
Loa Loa (eye worm) hypothetical protein 0.0046 0.0062 0.1187
Schistosoma mansoni hypothetical protein 0.0403 0.0696 0.5761
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.05 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0039
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0007 0.0061
Giardia lamblia Kinase, STE STE20 0.0075 0.0113 0.037
Loa Loa (eye worm) calpain 0.0019 0.0014 0.0266
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0019 0.0014 0.0026

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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