TDR Targets

Basic information

Technical information

TDR Targets ID: 739907
Name: 1-(3,4-dichlorophenyl)-2-[(4-methyl-5-pyridin -3-yl-1,2,4-triazol-3-yl)sulfanyl]ethanone
MW: 379.264 | Formula: C16H12Cl2N4OS
H donors: 0 H acceptors: 4 LogP: 3.53 Rotable bonds: 5
Rule of 5 violations (Lipinski): 1
SMILES: O=C(c1ccc(c(c1)Cl)Cl)CSc1nnc(n1C)c1cccnc1
InChi: 1S/C16H12Cl2N4OS/c1-22-15(11-3-2-6-19-8-11)20-21-16(22)24-9-14(23)10-4-5-12(17)13(18)7-10/h2-8H,9H2,1H3
InChiKey: RVLMUQRQISUAFP-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

1-(3,4-dichlorophenyl)-2-[[4-methyl-5-(3-pyridyl)-1,2,4-triazol-3-yl]sulfanyl]ethanone
1-(3,4-dichlorophenyl)-2-[[4-methyl-5-(3-pyridyl)-1,2,4-triazol-3-yl]thio]ethanone
ZINC02865770

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	tar DNA-binding protein	0.0071	0.0483	0.0483
Brugia malayi	MH2 domain containing protein	0.0239	0.2016	0.1996
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0081	0.0581	0.0765
Echinococcus multilocularis	lamin dm0	0.0054	0.0327	0.0431
Echinococcus multilocularis	Endonuclease G	0.0311	0.2668	0.3514
Loa Loa (eye worm)	beta-lactamase	0.0075	0.0522	0.0517
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0518	0.4547	0.5988
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0075	0.0522	0.0522
Schistosoma mansoni	lamin	0.0054	0.0327	0.0327
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0259	0.0342
Onchocerca volvulus		0.0518	0.4547	0.4366
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0047	0.0268	0.0353
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0075	0.0522	0.0499
Loa Loa (eye worm)	hypothetical protein	0.0081	0.0581	0.0576
Echinococcus granulosus	tumor protein p63	0.0361	0.3123	0.4113
Onchocerca volvulus		0.006	0.0385	0.0066
Schistosoma mansoni	intermediate filament proteins	0.0054	0.0327	0.0327
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0501	0.0496
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0075	0.0522	0.0688
Onchocerca volvulus	GPI ethanolamine phosphate transferase 3 homolog	0.0081	0.0581	0.0268
Loa Loa (eye worm)	hypothetical protein	0.0081	0.0581	0.0576
Echinococcus multilocularis	GPCR, family 2	0.0047	0.0268	0.0353
Brugia malayi	beta-lactamase family protein	0.0075	0.0522	0.0499
Schistosoma mansoni	tar DNA-binding protein	0.0071	0.0483	0.0483
Echinococcus granulosus	cytoplasmic intermediate filament protein	0.0026	0.0075	0.0099
Toxoplasma gondii	DNA/RNA non-specific endonuclease	0.0311	0.2668	1
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0081	0.0581	0.0765
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0268	0.0262
Brugia malayi	RNA recognition motif domain containing protein	0.0071	0.0483	0.0459
Schistosoma mansoni	ectonucleotide pyrophosphatase/phosphodiesterase	0.0081	0.0581	0.0581
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0327	0.0322
Schistosoma mansoni	tar DNA-binding protein	0.0071	0.0483	0.0483
Leishmania major	ethanolamine phosphotransferase, putative	0.0081	0.0581	0.1969
Loa Loa (eye worm)	hypothetical protein	0.0081	0.0581	0.0576
Brugia malayi	cytoplasmic intermediate filament protein	0.0029	0.0101	0.0077
Plasmodium falciparum	GPI ethanolamine phosphate transferase 3, putative	0.0081	0.0581	1
Schistosoma mansoni	microtubule-associated protein tau	0.0689	0.6098	0.6098
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0518	0.4547	0.5988
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0019	0.0012	0.0016
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0259	0.0342
Brugia malayi	Bromodomain containing protein	0.0081	0.0572	0.0549
Trypanosoma cruzi	endonuclease G, putative	0.0311	0.2668	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0318	0.0313
Echinococcus multilocularis	zinc finger protein	0.0024	0.0055	0.0072
Brugia malayi	TAR-binding protein	0.0071	0.0483	0.0459
Loa Loa (eye worm)	PHD-finger family protein	0.0021	0.0033	0.0028
Loa Loa (eye worm)	RNA binding protein	0.0071	0.0483	0.0477
Toxoplasma gondii	ABC1 family protein	0.0075	0.0522	0.1743
Echinococcus granulosus	ectonucleotide	0.0437	0.3807	0.5013
Schistosoma mansoni	tar DNA-binding protein	0.0071	0.0483	0.0483
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0067	0.0061
Echinococcus multilocularis	cytoplasmic intermediate filament protein	0.0026	0.0075	0.0099
Loa Loa (eye worm)	type I phosphodiesterase/nucleotide pyrophosphatase	0.0081	0.0581	0.0576
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0221	0.0216
Echinococcus granulosus	gpi ethanolamine phosphate transferase 3	0.0081	0.0581	0.0765
Loa Loa (eye worm)	transcription factor SMAD2	0.0239	0.2016	0.2011
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0259	0.0259
Leishmania major	DNA/RNA non-specific endonuclease-like protein	0.0311	0.2668	1
Entamoeba histolytica	phosphatidylinositol-glycan biosynthesis class O protein, putative	0.0081	0.0581	0.5
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0522	0.0517
Brugia malayi	beta-lactamase	0.0075	0.0522	0.0499
Loa Loa (eye worm)	hypothetical protein	0.0518	0.4547	0.4544
Onchocerca volvulus		0.0054	0.0327	0.0006
Loa Loa (eye worm)	histone methyltransferase	0.0019	0.0009	0.0003
Brugia malayi	Latrophilin receptor protein 2	0.0047	0.0268	0.0244
Schistosoma mansoni	hypothetical protein	0.0081	0.0581	0.0581
Trypanosoma cruzi	DNA/RNA non-specific endonuclease protein-like, putative	0.0311	0.2668	1
Echinococcus multilocularis	musashi	0.0054	0.0327	0.0431
Schistosoma mansoni	hypothetical protein	0.0047	0.0268	0.0268
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0046	0.0259	0.0254
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0522	0.0517
Trichomonas vaginalis	D-aminoacylase, putative	0.0075	0.0522	0.5
Echinococcus multilocularis	cpg binding protein	0.0065	0.0434	0.0572
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0522	0.0517
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0518	0.4547	0.5988
Schistosoma mansoni	hypothetical protein	0.0081	0.0581	0.0581
Echinococcus granulosus	beta LACTamase domain containing family member	0.0075	0.0522	0.0688
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0071	0.0483	0.0477
Echinococcus multilocularis	tumor protein p63	0.0361	0.3123	0.4113
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0075	0.0522	0.0522
Schistosoma mansoni	bromodomain containing protein	0.0068	0.0463	0.0463
Echinococcus granulosus	tar DNA binding protein	0.0071	0.0483	0.0636
Onchocerca volvulus	Ectonucleotide pyrophosphatase\/phosphodiesterase family member 7 homolog	0.0081	0.0581	0.0268
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0518	0.4547	0.5988
Echinococcus granulosus	lamin dm0	0.0054	0.0327	0.0431
Loa Loa (eye worm)	MH2 domain-containing protein	0.0239	0.2016	0.2011
Loa Loa (eye worm)	cytoplasmic intermediate filament protein	0.0029	0.0101	0.0096
Entamoeba histolytica	phosphatidylinositol-glycan biosynthesis class O protein, putative	0.0081	0.0581	0.5
Loa Loa (eye worm)	hypothetical protein	0.0047	0.027	0.0264
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0199	0.0193
Plasmodium vivax	hypothetical protein, conserved	0.0075	0.0522	1
Echinococcus multilocularis	tar DNA binding protein	0.0071	0.0483	0.0636
Schistosoma mansoni	hypothetical protein	0.0047	0.0268	0.0268
Echinococcus multilocularis	transferase	0.0081	0.0581	0.0765
Schistosoma mansoni	hypothetical protein	0.0171	0.1392	0.1392
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0046	0.0259	0.0235
Schistosoma mansoni	cellular tumor antigen P53	0.0053	0.0321	0.0321
Echinococcus granulosus	GPCR family 2	0.0047	0.0268	0.0353
Loa Loa (eye worm)	TAR-binding protein	0.0071	0.0483	0.0477
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.0037	0.0176	0.0232
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0437	0.3807	0.5013
Trichomonas vaginalis	D-aminoacylase, putative	0.0075	0.0522	0.5
Trypanosoma cruzi	hypothetical protein, conserved	0.0075	0.0522	0.1743
Brugia malayi	AEL166Cp	0.0081	0.0581	0.0557
Brugia malayi	hypothetical protein	0.0081	0.0581	0.0557
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0518	0.4547	0.5988
Brugia malayi	Type I phosphodiesterase / nucleotide pyrophosphatase family protein	0.0518	0.4547	0.4533
Mycobacterium ulcerans	hypothetical protein	0.0081	0.0581	1
Brugia malayi	Type I phosphodiesterase / nucleotide pyrophosphatase family protein	0.0081	0.0581	0.0557
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0518	0.4547	0.5988
Onchocerca volvulus		0.0054	0.0327	0.0006
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0047	0.0268	0.0353
Onchocerca volvulus	GPI ethanolamine phosphate transferase 2 homolog	0.0081	0.0581	0.0268
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0149	0.119	0.1168
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.0037	0.0176	0.0232
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0149	0.119	0.1168
Echinococcus multilocularis	dnaJ subfamily B	0.0854	0.7593	1
Echinococcus granulosus	intermediate filament protein	0.0054	0.0327	0.0431
Echinococcus multilocularis	microtubule associated protein 2	0.0689	0.6098	0.803
Loa Loa (eye worm)	thrombospondin type 1 domain-containing protein	0.1119	1	1
Trichomonas vaginalis	esterase, putative	0.0075	0.0522	0.5
Schistosoma mansoni	cpg binding protein	0.0065	0.0434	0.0434
Brugia malayi	Bromodomain containing protein	0.0039	0.0198	0.0174
Echinococcus granulosus	microtubule associated protein 2	0.0689	0.6098	0.803
Echinococcus granulosus	transferase	0.0081	0.0581	0.0765
Leishmania major	hypothetical protein, conserved	0.0075	0.0522	0.1743
Trichomonas vaginalis	penicillin-binding protein, putative	0.0075	0.0522	0.5
Loa Loa (eye worm)	intermediate filament protein	0.0054	0.0327	0.0322
Brugia malayi	hypothetical protein	0.0025	0.0069	0.0045
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0518	0.4547	0.5988
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0081	0.0581	0.0765
Echinococcus granulosus	dnaJ subfamily B	0.0854	0.7593	1
Echinococcus multilocularis	ectonucleotide	0.0437	0.3807	0.5013
Trypanosoma cruzi	DNA/RNA non-specific endonuclease protein-like, putative	0.0311	0.2668	1
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0012	0.0006
Brugia malayi	hypothetical protein	0.0081	0.0581	0.0557
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0149	0.119	0.1185
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0047	0.0268	0.0353
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0479	0.4195	1
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0054	0.0327	0.0322
Onchocerca volvulus	GPI ethanolamine phosphate transferase 1 homolog	0.0081	0.0581	0.0268
Brugia malayi	CXXC zinc finger family protein	0.006	0.0385	0.0361
Echinococcus multilocularis	geminin	0.0171	0.1392	0.1833
Trypanosoma brucei	endonuclease G, putative	0.0311	0.2668	1
Onchocerca volvulus		0.1119	1	1
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0518	0.4547	0.5988
Loa Loa (eye worm)	hypothetical protein	0.0437	0.3807	0.3803
Echinococcus multilocularis	gpi ethanolamine phosphate transferase 3	0.0081	0.0581	0.0765
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.0065	0.0429	0.0565
Echinococcus multilocularis	gpi ethanolamine phosphate transferase 1	0.0081	0.0581	0.0765
Schistosoma mansoni	ectonucleotide pyrophosphatase/phosphodiesterase	0.0518	0.4547	0.4547
Leishmania major	endonuclease G, putative	0.0311	0.2668	1
Loa Loa (eye worm)	hypothetical protein	0.0081	0.0581	0.0576
Brugia malayi	beta-lactamase family protein	0.0075	0.0522	0.0499
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0518	0.4547	0.5988
Schistosoma mansoni	ectonucleotide pyrophosphatase/phosphodiesterase	0.0518	0.4547	0.4547
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0019	0.0009	0.0012
Onchocerca volvulus		0.0075	0.0522	0.0208
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0259	0.0342
Loa Loa (eye worm)	hypothetical protein	0.0518	0.4547	0.4544
Brugia malayi	Intermediate filament tail domain containing protein	0.0054	0.0327	0.0303
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0047	0.0268	0.0244
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0518	0.4547	0.5988
Brugia malayi	endonuclease G, mitochondrial precursor	0.0311	0.2668	0.265
Echinococcus granulosus	fetal alzheimer antigen falz	0.0027	0.0082	0.0108
Echinococcus granulosus	lamin	0.0054	0.0327	0.0431
Loa Loa (eye worm)	CXXC zinc finger family protein	0.006	0.0385	0.038
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0047	0.0268	0.0353
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0259	0.0259
Echinococcus granulosus	histone lysine methyltransferase setb	0.0019	0.0012	0.0016
Schistosoma mansoni	hypothetical protein	0.0081	0.0581	0.0581
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0259	0.0342
Schistosoma mansoni	acetyl-CoA C-acetyltransferase	0.0027	0.0082	0.0082
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0047	0.0268	0.0262
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0075	0.007
Brugia malayi	intermediate filament protein	0.0054	0.0327	0.0303
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0522	0.0517
Trypanosoma cruzi	hypothetical protein, conserved	0.0075	0.0522	0.1743
Schistosoma mansoni	hypothetical protein	0.0854	0.7593	0.7593
Onchocerca volvulus		0.0075	0.0522	0.0208
Trichomonas vaginalis	penicillin-binding protein, putative	0.0075	0.0522	0.5
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0321	0.0316
Schistosoma mansoni	tar DNA-binding protein	0.0071	0.0483	0.0483
Schistosoma mansoni	cpg binding protein	0.0065	0.0434	0.0434
Loa Loa (eye worm)	hypothetical protein	0.0102	0.0763	0.0758
Trypanosoma brucei	hypothetical protein, conserved	0.0075	0.0522	0.1743
Schistosoma mansoni	hypothetical protein	0.0171	0.1392	0.1392
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0127	0.0995	0.0995
Loa Loa (eye worm)	hypothetical protein	0.0149	0.119	0.1185
Brugia malayi	PHD-finger family protein	0.0029	0.0104	0.008
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0116	0.0894	0.3174
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0019	0.0012	0.0012
Echinococcus multilocularis	lamin	0.0054	0.0327	0.0431
Schistosoma mansoni	endonuclease related	0.0311	0.2668	0.2668
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.0065	0.0429	0.0565
Loa Loa (eye worm)	hypothetical protein	0.0518	0.4547	0.4544
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0067	0.0061
Schistosoma mansoni	hypothetical protein	0.0102	0.0763	0.0763
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0518	0.4547	0.5988
Trypanosoma brucei	endonuclease G, putative	0.0311	0.2668	1
Echinococcus granulosus	cpg binding protein	0.0065	0.0434	0.0572
Schistosoma mansoni	hypothetical protein	0.1119	1	1
Echinococcus granulosus	geminin	0.0171	0.1392	0.1833
Schistosoma mansoni	ectonucleotide pyrophosphatase/phosphodiesterase	0.0518	0.4547	0.4547
Brugia malayi	RNA binding protein	0.0071	0.0483	0.0459
Trypanosoma brucei	endonuclease G, putative	0.0311	0.2668	1
Schistosoma mansoni	ectonucleotide pyrophosphatase/phosphodiesterase	0.0518	0.4547	0.4547
Echinococcus multilocularis	fetal alzheimer antigen, falz	0.0027	0.0082	0.0108
Trypanosoma cruzi	endonuclease G, putative	0.0311	0.2668	1
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0069	0.0064
Brugia malayi	latrophilin 2 splice variant baaae	0.0102	0.0763	0.074
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0019	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0522	0.0517
Schistosoma mansoni	zinc finger protein	0.0024	0.0055	0.0055
Giardia lamblia	Phosphatidylinositol-glycan biosynthesis, class O protein	0.0081	0.0581	0.5
Schistosoma mansoni	lamin	0.0054	0.0327	0.0327
Onchocerca volvulus		0.0518	0.4547	0.4366
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0075	0.0522	0.0517
Echinococcus granulosus	Endonuclease G	0.0311	0.2668	0.3514
Onchocerca volvulus	Ectonucleotide pyrophosphatase\/phosphodiesterase family member 6 homolog	0.0081	0.0581	0.0268
Schistosoma mansoni	hypothetical protein	0.0047	0.0268	0.0268
Schistosoma mansoni	hypothetical protein	0.0047	0.0268	0.0268
Schistosoma mansoni	hypothetical protein	0.0081	0.0581	0.0581
Trichomonas vaginalis	D-aminoacylase, putative	0.0075	0.0522	0.5
Schistosoma mansoni	cpg binding protein	0.006	0.0385	0.0385
Mycobacterium leprae	hypothetical protein	0.0081	0.0581	1
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0019	0.0009	0.0012
Echinococcus multilocularis	Alkaline phosphatase, core domain	0.0081	0.0581	0.0765
Echinococcus granulosus	zinc finger protein	0.0024	0.0055	0.0072
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0259	0.0259
Schistosoma mansoni	hypothetical protein	0.0021	0.0033	0.0033
Onchocerca volvulus		0.0075	0.0522	0.0208
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0522	0.0517
Trypanosoma brucei	GPI ethanolamine phosphate transferase 3, putative	0.0081	0.0581	0.1969
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0437	0.3807	0.5013

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by Saint Jude

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 739907