Detailed information for compound 740140

Basic information

Technical information
  • TDR Targets ID: 740140
  • Name: 4-oxo-4-[[4-(piperidin-1-ylmethyl)phenyl]amin o]butanoic acid
  • MW: 290.357 | Formula: C16H22N2O3
  • H donors: 2 H acceptors: 3 LogP: -1.07 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc(cc1)CN1CCCCC1)CCC(=O)O
  • InChi: 1S/C16H22N2O3/c19-15(8-9-16(20)21)17-14-6-4-13(5-7-14)12-18-10-2-1-3-11-18/h4-7H,1-3,8-12H2,(H,17,19)(H,20,21)
  • InChiKey: GVFFRVXULOXBST-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-oxo-4-[[4-(1-piperidylmethyl)phenyl]amino]butanoic acid
  • 4-keto-4-[[4-(piperidinomethyl)phenyl]amino]butyric acid
  • BAS 05596341
  • N-(4-Piperidin-1-ylmethyl-phenyl)-succinamic acid
  • SBB012277
  • ZINC00795284

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus transferase 0.0082 0.0592 0.093
Brugia malayi CXXC zinc finger family protein 0.003 0.0123 0.0118
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0424 0.0424
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0208 0.0317
Echinococcus multilocularis lamin dm0 0.0082 0.0588 0.0924
Echinococcus granulosus gpi ethanolamine phosphate transferase 3 0.0082 0.0592 0.093
Loa Loa (eye worm) RNA binding protein 0.0063 0.0424 0.0415
Echinococcus granulosus beta LACTamase domain containing family member 0.011 0.0847 0.1336
Echinococcus multilocularis geminin 0.0177 0.1446 0.2291
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0009 0.0009
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.011 0.0847 0.0839
Mycobacterium ulcerans beta-lactamase 0.011 0.0847 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0153 0.1227 0.1223
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0283 0.0279
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0051 0.0042
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0522 0.4554 0.7243
Entamoeba histolytica phosphatidylinositol-glycan biosynthesis class O protein, putative 0.0082 0.0592 0.5
Loa Loa (eye worm) hypothetical protein 0.0047 0.0278 0.0269
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0522 0.4554 0.4554
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0522 0.4554 0.7243
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0314 0.2677 1
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0082 0.0592 0.0475
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0283 0.0437
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0198 0.0301
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0283 0.0283
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0522 0.4554 0.4554
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0283 0.0283
Echinococcus granulosus cpg binding protein 0.0034 0.0157 0.0236
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0314 0.2677 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0442 0.0689
Schistosoma mansoni bromodomain containing protein 0.0069 0.0476 0.0476
Loa Loa (eye worm) hypothetical protein 0.011 0.0847 0.0839
Loa Loa (eye worm) hypothetical protein 0.011 0.0847 0.0839
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0198 0.0301
Loa Loa (eye worm) hypothetical protein 0.0082 0.0592 0.0584
Loa Loa (eye worm) hypothetical protein 0.0082 0.0588 0.058
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0283 0.0437
Echinococcus granulosus lamin 0.0082 0.0588 0.0924
Brugia malayi hypothetical protein 0.0082 0.0592 0.0588
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.1127 1 1
Schistosoma mansoni smad1 5 8 and 0.0017 0.0009 0.0009
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0522 0.4554 0.4554
Brugia malayi PHD-finger family protein 0.0028 0.0108 0.0103
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0085 0.0085
Brugia malayi beta-lactamase 0.011 0.0847 0.0843
Leishmania major endonuclease G, putative 0.0314 0.2677 1
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0522 0.4554 0.7243
Trypanosoma brucei endonuclease G, putative 0.0314 0.2677 1
Onchocerca volvulus 0.011 0.0847 0.0733
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0026 0.0088 0.0079
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0082 0.0592 0.093
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.0847 0.5
Echinococcus multilocularis Alkaline phosphatase, core domain 0.0082 0.0592 0.093
Echinococcus multilocularis gpi ethanolamine phosphate transferase 1 0.0082 0.0592 0.093
Echinococcus multilocularis gpi ethanolamine phosphate transferase 3 0.0082 0.0592 0.093
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0082 0.0592 0.0592
Onchocerca volvulus 0.011 0.0847 0.0733
Schistosoma mansoni zinc finger protein 0.0023 0.0056 0.0056
Brugia malayi beta-lactamase family protein 0.011 0.0847 0.0843
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0014
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0085 0.0121
Schistosoma mansoni hypothetical protein 0.0048 0.0288 0.0288
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0082 0.0592 0.093
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.0314 0.2677 1
Loa Loa (eye worm) type I phosphodiesterase/nucleotide pyrophosphatase 0.0082 0.0592 0.0584
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0247 0.0238
Onchocerca volvulus 0.0522 0.4554 0.4486
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0424 0.0419
Onchocerca volvulus 0.0082 0.0588 0.0471
Brugia malayi MH2 domain containing protein 0.0254 0.2139 0.2135
Echinococcus multilocularis beta LACTamase domain containing family member 0.011 0.0847 0.1336
Brugia malayi MH1 domain containing protein 0.0017 0.0009 0.0004
Brugia malayi RNA binding protein 0.0063 0.0424 0.0419
Echinococcus granulosus intermediate filament protein 0.0082 0.0588 0.0924
Brugia malayi MH1 domain containing protein 0.0017 0.0009 0.0004
Leishmania major hypothetical protein, conserved 0.011 0.0847 0.3166
Schistosoma mansoni cellular tumor antigen P53 0.0101 0.0764 0.0764
Schistosoma mansoni cpg binding protein 0.0034 0.0157 0.0157
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0075 0.0532 0.0523
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0442 0.0689
Loa Loa (eye worm) beta-lactamase 0.011 0.0847 0.0839
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0283 0.0275
Schistosoma mansoni hypothetical protein 0.0082 0.0592 0.0592
Plasmodium falciparum GPI ethanolamine phosphate transferase 3, putative 0.0082 0.0592 1
Schistosoma mansoni cpg binding protein 0.003 0.0123 0.0123
Echinococcus multilocularis cpg binding protein 0.0034 0.0157 0.0236
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.011 0.0847 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0244 0.0235
Trypanosoma cruzi endonuclease G, putative 0.0314 0.2677 1
Schistosoma mansoni hypothetical protein 0.0048 0.0288 0.0288
Plasmodium vivax hypothetical protein, conserved 0.011 0.0847 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0085 0.0121
Toxoplasma gondii ABC1 family protein 0.011 0.0847 0.2933
Schistosoma mansoni hypothetical protein 0.0082 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0082 0.0592 0.0584
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0522 0.4554 0.7243
Brugia malayi TAR-binding protein 0.0063 0.0424 0.0419
Echinococcus multilocularis GPCR, family 2 0.0048 0.0288 0.0445
Trypanosoma brucei endonuclease G, putative 0.0314 0.2677 1
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0424 0.0424
Echinococcus multilocularis musashi 0.0082 0.0588 0.0924
Onchocerca volvulus Ectonucleotide pyrophosphatase\/phosphodiesterase family member 6 homolog 0.0082 0.0592 0.0475
Giardia lamblia Phosphatidylinositol-glycan biosynthesis, class O protein 0.0082 0.0592 0.5
Schistosoma mansoni hypothetical protein 0.0427 0.3699 0.3699
Brugia malayi AEL166Cp 0.0082 0.0592 0.0588
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0426 0.0426
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0288 0.0445
Echinococcus multilocularis lamin 0.0082 0.0588 0.0924
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0019 0.0023 0.0022
Schistosoma mansoni hypothetical protein 0.0082 0.0592 0.0592
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0082 0.0592 0.093
Loa Loa (eye worm) hypothetical protein 0.0522 0.4554 0.4549
Brugia malayi Smad1 0.0017 0.0009 0.0004
Schistosoma mansoni hypothetical protein 0.0177 0.1446 0.1446
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0387 0.1156
Schistosoma mansoni hypothetical protein 0.0048 0.0288 0.0288
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0247 0.0242
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0288 0.0283
Entamoeba histolytica phosphatidylinositol-glycan biosynthesis class O protein, putative 0.0082 0.0592 0.5
Onchocerca volvulus 0.0522 0.4554 0.4486
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0424 0.0424
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0283 0.0437
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0153 0.1227 0.1219
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.044 0.3814 0.6065
Onchocerca volvulus GPI ethanolamine phosphate transferase 3 homolog 0.0082 0.0592 0.0475
Mycobacterium leprae Probable lipase LipE 0.011 0.0847 1
Loa Loa (eye worm) hypothetical protein 0.0522 0.4554 0.4549
Mycobacterium ulcerans hypothetical protein 0.011 0.0847 1
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0522 0.4554 0.7243
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0017 0.0013
Schistosoma mansoni smad1 5 8 and 0.0017 0.0009 0.0009
Echinococcus multilocularis tumor protein p63 0.0691 0.6078 0.9673
Brugia malayi latrophilin 2 splice variant baaae 0.0104 0.0792 0.0788
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0082 0.0588 0.058
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0424 0.0415
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0522 0.4554 0.7243
Brugia malayi Calcitonin receptor-like protein seb-1 0.0153 0.1227 0.1223
Schistosoma mansoni microtubule-associated protein tau 0.0714 0.6283 0.6283
Echinococcus granulosus tumor protein p63 0.0691 0.6078 0.9673
Brugia malayi MH2 domain containing protein 0.0017 0.0009 0.0004
Schistosoma mansoni hypothetical protein 0.1127 1 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0221 0.0213
Loa Loa (eye worm) hypothetical protein 0.044 0.3814 0.3809
Loa Loa (eye worm) hypothetical protein 0.008 0.0575 0.0567
Trypanosoma cruzi endonuclease G, putative 0.0314 0.2677 1
Onchocerca volvulus 0.1127 1 1
Echinococcus multilocularis ectonucleotide 0.044 0.3814 0.6065
Loa Loa (eye worm) hypothetical protein 0.0522 0.4554 0.4549
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.011 0.0847 0.0847
Echinococcus multilocularis dnaJ subfamily B 0.0427 0.3699 0.5881
Echinococcus multilocularis Endonuclease G 0.0314 0.2677 0.4252
Echinococcus granulosus microtubule associated protein 2 0.0714 0.6283 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0088 0.0329
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0522 0.4554 0.7243
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0023 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0424 0.0424
Mycobacterium ulcerans esterase/lipase LipP 0.011 0.0847 1
Schistosoma mansoni lamin 0.0082 0.0588 0.0588
Trichomonas vaginalis penicillin-binding protein, putative 0.011 0.0847 0.5
Brugia malayi MH2 domain containing protein 0.0017 0.0009 0.0004
Schistosoma mansoni cpg binding protein 0.0034 0.0157 0.0157
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0424 0.0662
Echinococcus multilocularis transferase 0.0082 0.0592 0.093
Loa Loa (eye worm) intermediate filament protein 0.0082 0.0588 0.058
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0288 0.0445
Schistosoma mansoni smad1 5 8 and 0.0017 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0048 0.0288 0.0288
Echinococcus granulosus zinc finger protein 0.0023 0.0056 0.0076
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0017 0.0017
Onchocerca volvulus Ectonucleotide pyrophosphatase\/phosphodiesterase family member 7 homolog 0.0082 0.0592 0.0475
Echinococcus granulosus geminin 0.0177 0.1446 0.2291
Loa Loa (eye worm) hypothetical protein 0.0153 0.1227 0.1219
Trichomonas vaginalis penicillin-binding protein, putative 0.011 0.0847 0.5
Schistosoma mansoni hypothetical protein 0.0022 0.0051 0.0051
Echinococcus multilocularis microtubule associated protein 2 0.0714 0.6283 1
Schistosoma mansoni lamin 0.0082 0.0588 0.0588
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0017 0.0013
Schistosoma mansoni hypothetical protein 0.0177 0.1446 0.1446
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0522 0.4554 0.4554
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0082 0.0592 0.0588
Loa Loa (eye worm) hypothetical protein 0.0038 0.0195 0.0186
Trypanosoma brucei endonuclease G, putative 0.0314 0.2677 1
Schistosoma mansoni endonuclease related 0.0314 0.2677 0.2677
Onchocerca volvulus 0.011 0.0847 0.0733
Loa Loa (eye worm) hypothetical protein 0.011 0.0847 0.0839
Echinococcus granulosus tar DNA binding protein 0.0063 0.0424 0.0662
Echinococcus granulosus Endonuclease G 0.0314 0.2677 0.4252
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0123 0.0114
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0522 0.4554 0.7243
Leishmania major ethanolamine phosphotransferase, putative 0.0082 0.0592 0.2213
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0288 0.0283
Mycobacterium leprae conserved hypothetical protein 0.011 0.0847 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0088 0.0329
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0522 0.4554 0.7243
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0424 0.0415
Loa Loa (eye worm) hypothetical protein 0.0104 0.0792 0.0784
Echinococcus granulosus ectonucleotide 0.044 0.3814 0.6065
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0088 0.0329
Schistosoma mansoni smad 0.0017 0.0009 0.0009
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0522 0.4554 0.4551
Loa Loa (eye worm) hypothetical protein 0.0082 0.0592 0.0584
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0288 0.0279
Brugia malayi intermediate filament protein 0.0082 0.0588 0.0584
Onchocerca volvulus 0.0082 0.0588 0.0471
Loa Loa (eye worm) hypothetical protein 0.011 0.0847 0.0839
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0288 0.0445
Schistosoma mansoni intermediate filament proteins 0.0082 0.0588 0.0588
Schistosoma mansoni Smad4 0.0017 0.0009 0.0009
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.011 0.0847 0.0843
Echinococcus granulosus dnaJ subfamily B 0.0427 0.3699 0.5881
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.011 0.0847 0.0847
Echinococcus granulosus lamin dm0 0.0082 0.0588 0.0924
Schistosoma mansoni hypothetical protein 0.0104 0.0792 0.0792
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.0847 0.5
Brugia malayi endonuclease G, mitochondrial precursor 0.0314 0.2677 0.2673
Brugia malayi Bromodomain containing protein 0.0082 0.0588 0.0584
Loa Loa (eye worm) hypothetical protein 0.0101 0.0764 0.0756
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.044 0.3814 0.6065
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0023 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.011 0.0847 0.0839
Loa Loa (eye worm) MH2 domain-containing protein 0.0254 0.2139 0.2132
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0208 0.0317
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0706 0.6206 1
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0522 0.4554 0.7243
Echinococcus granulosus GPCR family 2 0.0048 0.0288 0.0445
Loa Loa (eye worm) hypothetical protein 0.0048 0.0288 0.0279
Leishmania major DNA/RNA non-specific endonuclease-like protein 0.0314 0.2677 1
Leishmania major hypothetical protein, conserved 0.0026 0.0088 0.0329
Brugia malayi hypothetical protein 0.0026 0.0088 0.0083
Echinococcus multilocularis zinc finger protein 0.0023 0.0056 0.0076
Brugia malayi beta-lactamase family protein 0.011 0.0847 0.0843
Trichomonas vaginalis esterase, putative 0.011 0.0847 0.5
Brugia malayi Intermediate filament tail domain containing protein 0.0082 0.0588 0.0584
Trypanosoma brucei GPI ethanolamine phosphate transferase 3, putative 0.0082 0.0592 0.2213
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0522 0.4554 0.7243
Trypanosoma cruzi hypothetical protein, conserved 0.011 0.0847 0.3166
Loa Loa (eye worm) hypothetical protein 0.0038 0.0195 0.0186
Loa Loa (eye worm) transcription factor SMAD2 0.0254 0.2139 0.2132
Trypanosoma cruzi hypothetical protein, conserved 0.011 0.0847 0.3166
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0288 0.0445
Loa Loa (eye worm) hypothetical protein 0.0082 0.0592 0.0584
Onchocerca volvulus 0.0101 0.0764 0.0649
Trypanosoma brucei hypothetical protein, conserved 0.011 0.0847 0.3166
Brugia malayi hypothetical protein 0.0082 0.0592 0.0588
Brugia malayi Bromodomain containing protein 0.0041 0.0221 0.0216
Schistosoma mansoni hypothetical protein 0.0082 0.0592 0.0592
Echinococcus granulosus histone lysine methyltransferase setb 0.0019 0.0023 0.0022
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0283 0.0437
Loa Loa (eye worm) hypothetical protein 0.011 0.0847 0.0839
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0017 0.0017
Mycobacterium ulcerans lipase LipD 0.011 0.0847 1
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.0847 0.5
Loa Loa (eye worm) hypothetical protein 0.0039 0.0208 0.0199
Onchocerca volvulus GPI ethanolamine phosphate transferase 2 homolog 0.0082 0.0592 0.0475

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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