Detailed information for compound 907608

Basic information

Technical information
  • TDR Targets ID: 907608
  • Name: morpholin-4-yl-(4-prop-2-enoxyphenyl)methanon e
  • MW: 247.29 | Formula: C14H17NO3
  • H donors: 0 H acceptors: 1 LogP: 1.62 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCOc1ccc(cc1)C(=O)N1CCOCC1
  • InChi: 1S/C14H17NO3/c1-2-9-18-13-5-3-12(4-6-13)14(16)15-7-10-17-11-8-15/h2-6H,1,7-11H2
  • InChiKey: CTXKZZZMALOYPL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (4-allyloxyphenyl)-morpholino-methanone
  • (4-allyloxyphenyl)-morpholinomethanone
  • Oprea1_512675
  • ChemDiv2_000409
  • STK003459
  • ZINC04549183

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Cytochrome P450 family protein 0.0032 0.0081 0.0144
Loa Loa (eye worm) hypothetical protein 0.0037 0.0144 0.0258
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0042 0.0051
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0306 0.0547
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0144 0.0697
Onchocerca volvulus 0.0029 0.0042 0.016
Brugia malayi glutaminase DH11.1 0.0267 0.307 0.5492
Loa Loa (eye worm) endoplasmin 0.0026 0.0000046333 0.0000082892
Schistosoma mansoni pyruvate dehydrogenase 0.0465 0.559 0.6774
Schistosoma mansoni hypothetical protein 0.0032 0.0081 0.0098
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0444 0.0538
Leishmania major cytochrome p450-like protein 0.0041 0.0192 0.0344
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0042 0.0042
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0032 0.0081 0.1815
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0357 0.0433
Plasmodium falciparum DNA topoisomerase 2 0.0026 0.0000046333 0.5
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0032 0.0081 0.0263
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0163 0.174 0.3113
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0144 0.0697
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0032 0.0081 0.1815
Toxoplasma gondii protease inhibitor PI2 0.0037 0.0144 0.0697
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0026 0.0000046333 0.5
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0144 0.0258
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0032 0.0081 0.0263
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0032 0.0081 0.0263
Brugia malayi SPARC precursor 0.0037 0.0144 0.0258
Entamoeba histolytica hypothetical protein 0.0036 0.0129 1
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0144 0.0697
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0042 0.0203
Echinococcus granulosus microtubule associated protein 2 0.0675 0.8252 1
Echinococcus multilocularis 0.0032 0.0081 0.0081
Schistosoma mansoni glutaminase 0.0267 0.307 0.372
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0253 0.0307
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0253 0.0453
Loa Loa (eye worm) agrin synaptic family protein 0.0037 0.0144 0.0258
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0253 0.0307
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0032 0.0081 0.1815
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0444 0.0538
Loa Loa (eye worm) hypothetical protein 0.0037 0.0144 0.0258
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0032 0.0081 0.0263
Echinococcus multilocularis lamin 0.0026 0.0006 0.0006
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0032 0.0081 0.0263
Loa Loa (eye worm) hypothetical protein 0.005 0.0306 0.0547
Trypanosoma cruzi MFS transporter, putative 0.0055 0.0364 0.0652
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0028 0.0034
Schistosoma mansoni lamin 0.0026 0.0006 0.0007
Plasmodium falciparum DNA gyrase subunit B 0.0026 0.0000046333 0.5
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0129 0.0156
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0364 0.1392
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0032 0.0081 0.0263
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0032 0.0081 0.0144
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0032 0.0081 0.0263
Schistosoma mansoni hypothetical protein 0.017 0.1829 0.2217
Brugia malayi Cytochrome P450 family protein 0.0041 0.0192 0.0344
Brugia malayi intermediate filament protein 0.0026 0.0006 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0042 0.0051
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0006 0.0011
Loa Loa (eye worm) TOPoisomerase family member 0.0026 0.0000046333 0.0000082892
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0192 0.0344
Schistosoma mansoni pyruvate dehydrogenase 0.0439 0.526 0.6375
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0444 0.1447
Loa Loa (eye worm) cytochrome P450 family protein 0.0088 0.0795 0.1423
Onchocerca volvulus 0.0055 0.0364 0.1392
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0444 0.1447
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0032 0.0081 0.1815
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0042 0.0051
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0032 0.0081 0.0144
Plasmodium falciparum heat shock protein 90 0.0026 0.0000046333 0.5
Brugia malayi Cytochrome P450 family protein 0.0041 0.0192 0.0344
Loa Loa (eye worm) hypothetical protein 0.0055 0.0364 0.0652
Loa Loa (eye worm) hypothetical protein 0.0055 0.0364 0.0652
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0444 1
Loa Loa (eye worm) cytochrome P450 0.0032 0.0081 0.0144
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0444 0.2147
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0253 0.0307
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0006 0.0011
Echinococcus granulosus geminin 0.017 0.1829 0.2217
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0032 0.0081 0.0144
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0032 0.0081 0.1815
Loa Loa (eye worm) hypothetical protein 0.0055 0.0364 0.0652
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0026 0.0000046333 0.5
Toxoplasma gondii cytochrome p450 superfamily protein 0.0032 0.0081 0.039
Onchocerca volvulus 0.0026 0.0006 0.0023
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0465 0.559 0.559
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0026 0.0000046333 0.5
Schistosoma mansoni organic anion transporter 0.0055 0.0364 0.0441
Entamoeba histolytica hypothetical protein 0.0036 0.0129 1
Schistosoma mansoni follistatin 0.0037 0.0144 0.0175
Loa Loa (eye worm) hypothetical protein 0.0055 0.0364 0.0652
Leishmania major developmentally regulated phosphoprotein-like protein 0.0465 0.559 1
Schistosoma mansoni microtubule-associated protein tau 0.0675 0.8252 1
Brugia malayi Pre-SET motif family protein 0.0029 0.0042 0.0075
Loa Loa (eye worm) hypothetical protein 0.0026 0.0000046333 0.0000082892
Mycobacterium ulcerans glutaminase 0.0267 0.307 1
Trypanosoma brucei developmentally regulated phosphoprotein 0.0465 0.559 1
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0364 0.1392
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0144 0.0697
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0032 0.0081 0.1815
Schistosoma mansoni hypothetical protein 0.017 0.1829 0.2217
Brugia malayi secreted modular calcium-binding protein 1 0.0037 0.0144 0.0258
Brugia malayi hypothetical protein 0.0055 0.0364 0.0652
Echinococcus multilocularis follistatin 0.0037 0.0144 0.0144
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0163 0.174 0.8409
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0026 0.0000046333 0.5
Brugia malayi cytochrome P450 0.0032 0.0081 0.0144
Onchocerca volvulus 0.0055 0.0364 0.1392
Giardia lamblia Heat shock protein HSP 90-alpha 0.0026 0.0000046333 0.5
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0055 0.0364 0.0441
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0364 0.0652
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0364 0.1392
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0026 0.0000046333 0.5
Echinococcus granulosus Solute carrier organic anion transporter family 0.0055 0.0364 0.0441
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0465 0.559 0.6774
Trichomonas vaginalis glutaminase, putative 0.0267 0.307 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0364 0.0652
Schistosoma mansoni intermediate filament proteins 0.0026 0.0006 0.0007
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0041 0.0192 0.0626
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0032 0.0081 0.1815
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0032 0.0081 0.0263
Loa Loa (eye worm) heat shock protein 90 0.0026 0.0000046333 0.0000082892
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0026 0.0000046333 0.5
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0032 0.0081 0.0144
Loa Loa (eye worm) hypothetical protein 0.0055 0.0364 0.0652
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0032 0.0081 0.1815
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0444 0.0538
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.2259 0.4041
Entamoeba histolytica hypothetical protein 0.0036 0.0129 1
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0032 0.0081 0.0263
Loa Loa (eye worm) glutaminase 0.0267 0.307 0.5492
Echinococcus granulosus cytochrome P450 2K1 0.0032 0.0081 0.0098
Trypanosoma brucei cytochrome P450, putative 0.0041 0.0192 0.0344
Brugia malayi Pre-SET motif family protein 0.0203 0.2259 0.4041
Leishmania major cytochrome p450-like protein 0.0032 0.0081 0.0144
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0032 0.0081 0.0263
Onchocerca volvulus 0.0055 0.0364 0.1392
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.0192 0.0344
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0444 0.1447
Onchocerca volvulus 0.0037 0.0144 0.0551
Schistosoma mansoni agrin 0.0037 0.0144 0.0175
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0026 0.0000046333 0.5
Giardia lamblia Pms1-like protein 0.0026 0.0000046333 0.5
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.0192 0.0344
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0364 0.0652
Trichomonas vaginalis set domain proteins, putative 0.0232 0.2616 0.8522
Brugia malayi hypothetical protein 0.0036 0.0129 0.0231
Loa Loa (eye worm) hypothetical protein 0.0026 0.0000046333 0.0000082892
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0144 0.0258
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0032 0.0081 0.1815
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0163 0.174 0.3113
Chlamydia trachomatis DNA gyrase subunit B 0.0026 0.0000046333 0.5
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0032 0.0081 0.1815
Onchocerca volvulus 0.0055 0.0364 0.1392
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0032 0.0081 0.1815
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0055 0.0364 0.0652
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0253 0.0253
Entamoeba histolytica hypothetical protein 0.0036 0.0129 1
Brugia malayi prostaglandin transporter 0.0055 0.0364 0.0652
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0055 0.0364 0.0364
Echinococcus multilocularis lamin dm0 0.0026 0.0006 0.0006
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0006 0.0011
Echinococcus granulosus intermediate filament protein 0.0026 0.0006 0.0007
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0192 0.0344
Loa Loa (eye worm) hypothetical protein 0.0034 0.0105 0.0188
Plasmodium vivax SET domain protein, putative 0.0029 0.0042 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0144 0.0258
Echinococcus granulosus follistatin 0.0037 0.0144 0.0175
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0032 0.0081 0.1815
Mycobacterium leprae Conserved hypothetical protein 0.0032 0.0081 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0306 0.0547
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0032 0.0081 0.1815
Brugia malayi Cytochrome P450 family protein 0.0088 0.0795 0.1423
Chlamydia trachomatis DNA gyrase subunit B 0.0026 0.0000046333 0.5
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0144 0.0258
Brugia malayi hypothetical protein 0.0055 0.0364 0.0652
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0163 0.174 0.3113
Onchocerca volvulus 0.0055 0.0364 0.1392
Schistosoma mansoni cytochrome P450 0.0032 0.0081 0.0098
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0253 0.0253
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0042 0.0042
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0105 0.0188
Schistosoma mansoni pyruvate dehydrogenase 0.0439 0.526 0.6375
Echinococcus multilocularis agrin 0.0037 0.0144 0.0144
Echinococcus multilocularis geminin 0.017 0.1829 0.1829
Loa Loa (eye worm) CYP4Cod1 0.0041 0.0192 0.0344
Toxoplasma gondii transporter, major facilitator family protein 0.0055 0.0364 0.176
Echinococcus multilocularis expressed protein 0.0037 0.0144 0.0144
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0042 0.0051
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0032 0.0081 0.1815
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0032 0.0081 0.0263
Echinococcus multilocularis microtubule associated protein 2 0.0675 0.8252 0.8252
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0032 0.0081 0.1815
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0144 0.0258
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0253 0.0307
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0032 0.0081 0.0263
Onchocerca volvulus 0.0026 0.0006 0.0023
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0444 0.0795
Schistosoma mansoni organic anion transporter 0.0055 0.0364 0.0441
Echinococcus granulosus lamin 0.0026 0.0006 0.0007
Echinococcus granulosus agrin 0.0037 0.0144 0.0175
Leishmania major cytochrome p450-like protein 0.0032 0.0081 0.0144
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0306 0.0547
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0364 0.0652
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0042 0.0051
Loa Loa (eye worm) glutaminase 2 0.0267 0.307 0.5492
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0253 0.0453
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0253 0.0307
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0032 0.0081 0.1815
Onchocerca volvulus 0.0232 0.2616 1
Mycobacterium leprae putative cytochrome p450 0.0032 0.0081 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0144 0.0258
Echinococcus multilocularis musashi 0.0026 0.0006 0.0006
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0032 0.0081 0.0263
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0032 0.0081 0.0263
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0032 0.0081 0.0263
Schistosoma mansoni hypothetical protein 0.0036 0.0129 0.0156
Schistosoma mansoni hypothetical protein 0.0034 0.0105 0.0127
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0032 0.0081 0.1815
Brugia malayi kinase, mitochondrial precursor 0.0465 0.559 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0129 0.0129
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0032 0.0081 0.0263
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0444 0.0444
Loa Loa (eye worm) hypothetical protein 0.0465 0.559 1
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0032 0.0081 0.0263
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0055 0.0364 0.0364
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0144 0.0258
Loa Loa (eye worm) hypothetical protein 0.0055 0.0364 0.0652
Schistosoma mansoni lipoxygenase 0.0054 0.0357 0.0433
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0357 0.0357
Echinococcus granulosus lamin dm0 0.0026 0.0006 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0032 0.0081 0.1815
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0189 0.2069 1
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0465 0.559 1
Plasmodium falciparum endoplasmin, putative 0.0026 0.0000046333 0.5
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0032 0.0081 0.1815
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0032 0.0081 0.0263
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0032 0.0081 0.1815
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0011
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0129 0.0156
Schistosoma mansoni hypothetical protein 0.0052 0.033 0.0399
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0032 0.0081 0.0263
Schistosoma mansoni lamin 0.0026 0.0006 0.0007
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0032 0.0081 0.0144
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0032 0.0081 0.0263
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0465 0.559 0.559
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0075

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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