Detailed information for compound 936110

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 504.655 | Formula: C29H44O7
  • H donors: 0 H acceptors: 2 LogP: 5.85 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: C=CC(=C)CC[C@]1(C)[C@H](C)C[C@@H]([C@@]23[C@H]1C[C@@H](OC(=O)C(CC)C)C=C3[C@H](O[C@H]2OC(=O)C)OC)OC
  • InChi: 1S/C29H44O7/c1-10-17(3)12-13-28(7)19(5)14-24(32-8)29-22(26(33-9)36-27(29)34-20(6)30)15-21(16-23(28)29)35-25(31)18(4)11-2/h10,15,18-19,21,23-24,26-27H,1,3,11-14,16H2,2,4-9H3/t18?,19-,21+,23+,24+,26+,27-,28-,29-/m1/s1
  • InChiKey: XDGNGAAYVBELLQ-PJJSSYIVSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus FTZ F1 alpha 0.0023 0.0017 0.0017
Schistosoma mansoni RAR-like nuclear receptor 0.0023 0.0017 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0023 0.0017 0.0017
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0023 0.0017 0.0017
Echinococcus multilocularis thyroid hormone receptor alpha 0.0023 0.0017 0.0017
Echinococcus multilocularis dnaJ subfamily C 6 0.0066 0.0079 0.0079
Echinococcus granulosus Niemann Pick C1 protein 0.011 0.0143 0.0143
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0017 0.0017
Echinococcus multilocularis FTZ F1 alpha 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Onchocerca volvulus 0.0116 0.0152 0.0348
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0042 0.0042
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0023 0.0017 0.0017
Toxoplasma gondii exonuclease III APE 0.0041 0.0044 0.0162
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0041 0.0044 0.0339
Echinococcus granulosus GPCR family 2 0.0066 0.008 0.008
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0084 0.0084
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0053 0.0774
Schistosoma mansoni hypothetical protein 0.0045 0.005 0.005
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0241 0.0332 0.4864
Plasmodium vivax hypothetical protein, conserved 0.0241 0.0332 1
Echinococcus granulosus frizzled 0.0253 0.035 0.035
Echinococcus granulosus frizzled 0.0253 0.035 0.035
Echinococcus granulosus ecdysone induced protein 78C 0.0023 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0479 0.0675 0.0675
Onchocerca volvulus 0.0057 0.0066 0.0151
Brugia malayi beta-lactamase family protein 0.004 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0782 0.1112 0.1112
Onchocerca volvulus Dual oxidase homolog 0.0029 0.0027 0.0061
Loa Loa (eye worm) animal heme peroxidase 0.0029 0.0027 0.0027
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0114 0.0148 0.2542
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0041 0.0044 0.0162
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0012 0.0002 0.0002
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0041 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0454 0.6654
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0023 0.0017 0.0017
Brugia malayi hypothetical protein 0.0022 0.0016 0.0016
Brugia malayi hypothetical protein 0.0022 0.0016 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0084 0.0084
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0089 0.0112 0.0112
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.6948 1 1
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0047 0.0047
Chlamydia trachomatis replicative DNA helicase 0.0431 0.0606 1
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Brugia malayi hypothetical protein 0.0012 0.0002 0.0002
Schistosoma mansoni glutaminase 0.0292 0.0406 0.0406
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0042 0.0042
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0102 0.0132 0.0132
Brugia malayi prolyl oligopeptidase family protein 0.3044 0.4373 0.4373
Schistosoma mansoni hypothetical protein 0.0045 0.005 0.005
Loa Loa (eye worm) transcription factor SMAD2 0.0133 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.011 0.0143 0.0143
Onchocerca volvulus Protein ultraspiracle homolog 0.0023 0.0017 0.004
Schistosoma mansoni hypothetical protein 0.0066 0.008 0.008
Toxoplasma gondii ABC1 family protein 0.004 0.0042 0.0152
Echinococcus granulosus peroxidasin 0.0029 0.0027 0.0027
Loa Loa (eye worm) TAR-binding protein 0.0069 0.0084 0.0084
Echinococcus granulosus microtubule associated protein 2 0.1508 0.2158 0.2158
Trypanosoma brucei prolyl oligopeptidase, putative 0.0241 0.0332 0.2166
Treponema pallidum replicative DNA helicase (dnaB) 0.0431 0.0606 1
Schistosoma mansoni jumonji domain containing protein 0.0081 0.0101 0.0101
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.3044 0.4373 0.4373
Schistosoma mansoni peroxidasin 0.0029 0.0027 0.0027
Brugia malayi steroid hormone receptor 0.0023 0.0017 0.0017
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0241 0.0332 0.2166
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0023 0.0017 0.0017
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0241 0.0332 0.7025
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0047 0.0047
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0053 0.1567
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0066 0.008 0.008
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0005 0.0005
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0066 0.0066
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0119 0.0119
Onchocerca volvulus Huntingtin homolog 0.0137 0.0181 0.0415
Brugia malayi Animal haem peroxidase family protein 0.0029 0.0027 0.0027
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0044 0.0049 0.0049
Brugia malayi MH2 domain containing protein 0.0133 0.0176 0.0176
Brugia malayi nuclear hormone receptor 0.0023 0.0017 0.0017
Loa Loa (eye worm) prolyl oligopeptidase 0.0241 0.0332 0.0332
Echinococcus granulosus muscleblind protein 0.0482 0.0679 0.0679
Trichomonas vaginalis glutaminase, putative 0.0292 0.0406 0.5944
Loa Loa (eye worm) acetyltransferase 0.0162 0.0218 0.0218
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0073 0.0073
Entamoeba histolytica hypothetical protein 0.0114 0.0148 0.2542
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0089 0.0112 0.0112
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0454 0.6654
Echinococcus multilocularis peroxidasin 0.0029 0.0027 0.0027
Schistosoma mansoni frizzled-like receptor 0.0253 0.035 0.035
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.378 0.5434 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1694 0.2426 0.2426
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0253 0.035 0.035
Echinococcus multilocularis RUN 0.0022 0.0016 0.0016
Schistosoma mansoni frizzled-like receptor 0.0253 0.035 0.035
Loa Loa (eye worm) hypothetical protein 0.0137 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0241 0.0332 0.0332
Echinococcus granulosus dnaJ subfamily C 6 0.0066 0.0079 0.0079
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0132 0.0174 0.0174
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0024 0.0024
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0119 0.0119
Echinococcus multilocularis muscleblind protein 0.0482 0.0679 0.0679
Brugia malayi hypothetical protein 0.0114 0.0148 0.0148
Trichomonas vaginalis protein kinase inhibitor, putative 0.0066 0.0079 0.1153
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0044 0.129
Echinococcus multilocularis prolyl endopeptidase 0.0241 0.0332 0.0332
Echinococcus multilocularis muscleblind protein 1 0.0482 0.0679 0.0679
Mycobacterium tuberculosis Probable peptidase 0.0241 0.0332 0.0538
Toxoplasma gondii histone lysine methyltransferase SET1 0.0049 0.0054 0.0235
Schistosoma mansoni hypothetical protein 0.6948 1 1
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0017 0.0017
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.004 0.0042 0.0042
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0042 0.0042
Plasmodium falciparum MO15-related protein kinase 0.0128 0.0169 0.5065
Loa Loa (eye worm) glutaminase 2 0.0292 0.0406 0.0406
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0431 0.0606 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0044 0.0047 0.0084
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0089 0.0112 0.0112
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0241 0.0332 0.0332
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0066 0.008 0.008
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.1023 0.146 1
Loa Loa (eye worm) animal heme peroxidase 0.0029 0.0027 0.0027
Brugia malayi Doublecortin family protein 0.0022 0.0016 0.0016
Echinococcus granulosus expressed conserved protein 0.0103 0.0133 0.0133
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0044 0.129
Loa Loa (eye worm) hypothetical protein 0.021 0.0287 0.0287
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0041 0.0044 0.0044
Schistosoma mansoni intermediate filament proteins 0.0057 0.0066 0.0066
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0241 0.0332 0.4864
Brugia malayi Peroxidasin 0.0029 0.0027 0.0027
Entamoeba histolytica hypothetical protein 0.0114 0.0148 0.2542
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0023 0.0017 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0119 0.0119
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0084 0.0084
Echinococcus multilocularis secreted frizzled protein 0.0116 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0024
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0114 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.5507 0.7923 0.7923
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0023 0.0017 0.0017
Echinococcus multilocularis tar DNA binding protein 0.0069 0.0084 0.0084
Schistosoma mansoni lamin 0.0057 0.0066 0.0066
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.1023 0.146 1
Brugia malayi PHD-finger family protein 0.0011 0.0001 0.0001
Onchocerca volvulus Bile acid receptor homolog 0.0023 0.0017 0.004
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0029 0.0062
Echinococcus granulosus RUN 0.0022 0.0016 0.0016
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0041 0.0044 0.0162
Brugia malayi beta-lactamase family protein 0.004 0.0042 0.0042
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0102 0.0132 0.0132
Brugia malayi ecdysteroid receptor 0.0023 0.0017 0.0017
Loa Loa (eye worm) animal heme peroxidase 0.0029 0.0027 0.0027
Echinococcus granulosus short transient receptor potential channel 6 0.0077 0.0096 0.0096
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.6948 1 1
Echinococcus multilocularis frizzled 0.0253 0.035 0.035
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0033 0.0482
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0023 0.0017 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0023 0.0017 0.0017
Loa Loa (eye worm) prolyl oligopeptidase 0.3044 0.4373 0.4373
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0241 0.0332 0.7025
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0017 0.0017
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0137 0.0182 0.0182
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0023 0.0017 0.004
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0029 0.0029
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0241 0.0332 0.2166
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0454 0.6654
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0454 0.6654
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0023 0.0017 0.0017
Echinococcus multilocularis musashi 0.0057 0.0066 0.0066
Echinococcus granulosus Niemann Pick C1 protein 0.0157 0.0211 0.0211
Onchocerca volvulus Huntingtin homolog 0.0137 0.0181 0.0415
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0023 0.0017 0.0017
Schistosoma mansoni ap endonuclease 0.0041 0.0044 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0047 0.0047
Loa Loa (eye worm) glutaminase 0.0292 0.0406 0.0406
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0047 0.0052 0.0052
Echinococcus granulosus tar DNA binding protein 0.0069 0.0084 0.0084
Onchocerca volvulus 0.0048 0.0054 0.0123
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.3044 0.4373 0.4373
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.1023 0.146 1
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0253 0.035 0.035
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0073 0.0073
Brugia malayi glutaminase DH11.1 0.0292 0.0406 0.0406
Brugia malayi intermediate filament protein 0.0057 0.0066 0.0066
Echinococcus granulosus secreted frizzled protein 0.0116 0.0152 0.0152
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0047 0.0047
Trypanosoma cruzi prolyl endopeptidase 0.0241 0.0332 0.2166
Echinococcus granulosus geminin 0.0479 0.0675 0.0675
Echinococcus granulosus frizzled 4 0.0253 0.035 0.035
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0035
Schistosoma mansoni frizzled-like receptor 0.0137 0.0182 0.0182
Brugia malayi Calcitonin receptor-like protein seb-1 0.021 0.0287 0.0287
Echinococcus granulosus frizzled 5 0.0253 0.035 0.035
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0073 0.0073
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0089 0.0112 0.0112
Toxoplasma gondii prolyl endopeptidase 0.0241 0.0332 0.2166
Schistosoma mansoni lipoxygenase 0.0132 0.0174 0.0174
Onchocerca volvulus 0.0061 0.0073 0.0167
Echinococcus granulosus histone acetyltransferase KAT2B 0.0157 0.0211 0.0211
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0128 0.0169 0.5065
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0023 0.0017 0.0017
Brugia malayi jmjC domain containing protein 0.0102 0.0132 0.0132
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0058 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0241 0.0332 0.0538
Trypanosoma brucei prolyl endopeptidase 0.0241 0.0332 0.2166
Loa Loa (eye worm) hypothetical protein 0.0057 0.0066 0.0066
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0017 0.0017
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0071 0.0087 0.0087
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0241 0.0332 0.5145
Brugia malayi CXXC zinc finger family protein 0.0022 0.0017 0.0017
Echinococcus multilocularis frizzled 0.0253 0.035 0.035
Loa Loa (eye worm) hypothetical protein 0.0137 0.0182 0.0182
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0023 0.0017 0.0017
Schistosoma mansoni transient receptor potential channel 4 0.0115 0.0151 0.0151
Echinococcus multilocularis ecdysone induced protein 78C 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0025 0.0021 0.0021
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.3044 0.4373 1
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.1023 0.146 1
Mycobacterium ulcerans glutaminase 0.0292 0.0406 0.6453
Schistosoma mansoni hypothetical protein 0.0066 0.008 0.008
Brugia malayi DnaJ domain containing protein 0.0066 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.004 0.0042 0.0042
Schistosoma mansoni cpg binding protein 0.0024 0.0019 0.0019
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0017 0.0017
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0012 0.0002 0.0002
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0014 0.0005 0.0005
Brugia malayi acetyltransferase, GNAT family protein 0.0162 0.0218 0.0218
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.1023 0.146 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0017
Schistosoma mansoni transient receptor potential channel 0.0077 0.0096 0.0096
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0041 0.0044 0.0162
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0431 0.0606 1
Brugia malayi hypothetical protein 0.0012 0.0002 0.0002
Echinococcus multilocularis peregrin 0.0035 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0053 0.0062 0.0062
Echinococcus multilocularis secreted frizzled protein 5 0.0116 0.0152 0.0152
Onchocerca volvulus Peroxidasin homolog 0.0029 0.0027 0.0061
Brugia malayi Niemann-Pick C1 protein precursor 0.011 0.0143 0.0143
Onchocerca volvulus 0.0022 0.0017 0.0038
Onchocerca volvulus Prolyl endopeptidase homolog 0.0241 0.0332 0.076
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0253 0.035 0.035
Brugia malayi Animal haem peroxidase family protein 0.0029 0.0027 0.0027
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0042 0.0618
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0041 0.0044 0.0162
Schistosoma mansoni hypothetical protein 0.0144 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0115 0.0151 0.0151
Entamoeba histolytica prolyl oligopeptidase family protein 0.0241 0.0332 0.7025
Echinococcus granulosus smoothened 0.5623 0.8091 0.8091
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0023 0.0017 0.0017
Onchocerca volvulus 0.0029 0.0027 0.0061
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0029 0.0855
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.011 0.0143 0.241
Schistosoma mansoni hypothetical protein 0.6948 1 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0022
Echinococcus granulosus peregrin 0.0035 0.0035 0.0035
Onchocerca volvulus 0.0484 0.0683 0.1562
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0042 0.0618
Echinococcus granulosus TRP transient receptor potential channel 0.0044 0.0049 0.0049
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0241 0.0332 0.2166
Loa Loa (eye worm) hypothetical protein 0.0055 0.0064 0.0064
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0326 0.0454 1
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0038 0.004 0.004
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0016 0.0016
Treponema pallidum fructose-bisphosphate aldolase 0.0326 0.0454 0.7306
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0021 0.0586
Giardia lamblia Histone acetyltransferase GCN5 0.0044 0.0047 0.0421
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0041 0.0044 0.0026
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0241 0.0332 0.2166
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0066 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0241 0.0332 0.0332
Brugia malayi prolyl oligopeptidase family protein 0.1023 0.146 0.146
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0066 0.008 0.008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0454 0.6654
Onchocerca volvulus Alhambra homolog 0.0031 0.0029 0.0067
Echinococcus granulosus Dipeptidyl peptidase 9 0.1023 0.146 0.146
Brugia malayi hypothetical protein 0.0137 0.0181 0.0181
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0045 0.005 0.005
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.001 0.001
Brugia malayi CHE-14 protein 0.0047 0.0052 0.0052
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0073 0.0073
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0033 0.0482
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Schistosoma mansoni coup transcription factor 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Loa Loa (eye worm) steroid hormone receptor 0.0023 0.0017 0.0017
Schistosoma mansoni cpg binding protein 0.0024 0.0019 0.0019
Brugia malayi Animal haem peroxidase family protein 0.0029 0.0027 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0017 0.0017
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0039 0.0039
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0241 0.0332 0.1634
Echinococcus multilocularis frizzled 4 0.0253 0.035 0.035
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0012 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0042 0.0152
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0066 0.0066
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0112 0.0145 0.0145
Schistosoma mansoni hypothetical protein 0.0045 0.005 0.005
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0073 0.0073
Echinococcus multilocularis transient receptor potential ion channel A 0.0109 0.0142 0.0142
Loa Loa (eye worm) DnaJ domain-containing protein 0.0066 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0482 0.0679 0.0679
Schistosoma mansoni Replicative DNA helicase 0.0431 0.0606 0.0606
Brugia malayi RNA binding protein 0.0069 0.0084 0.0084
Giardia lamblia Fructose-bisphosphate aldolase 0.0326 0.0454 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.0152 0.0152
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.6948 1 1
Brugia malayi hypothetical protein 0.0782 0.1112 0.1112
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0012 0.0002 0.0002
Brugia malayi Latrophilin receptor protein 2 0.0066 0.008 0.008
Onchocerca volvulus 0.0022 0.0016 0.0037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0017 0.0017
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.021 0.0287 0.0287
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0024 0.0024
Echinococcus multilocularis protein dispatched 1 0.0054 0.0062 0.0062
Brugia malayi jmjC domain containing protein 0.0039 0.0041 0.0041
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.3044 0.4373 0.4373
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0454 0.6654
Loa Loa (eye worm) hypothetical protein 0.0241 0.0332 0.0332
Brugia malayi Fz domain containing protein 0.0116 0.0152 0.0152
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0044 0.0639
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Brugia malayi hypothetical protein 0.0029 0.0027 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0042 0.0152
Schistosoma mansoni mixed-lineage leukemia protein mll 0.005 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Echinococcus multilocularis dnaJ subfamily B 0.0318 0.0443 0.0443
Brugia malayi hypothetical protein 0.0025 0.0021 0.0021
Echinococcus multilocularis GPCR, family 2 0.0066 0.008 0.008
Echinococcus multilocularis voltage gated potassium channel 0.0014 0.0005 0.0005
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.012 0.0158 0.0652
Loa Loa (eye worm) hypothetical protein 0.0116 0.0152 0.0152
Trichomonas vaginalis esterase, putative 0.004 0.0042 0.0618
Echinococcus multilocularis expressed conserved protein 0.0103 0.0133 0.0133
Schistosoma mansoni frizzled 0.0253 0.035 0.035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0023 0.0017 0.0017
Schistosoma mansoni retinoic acid receptor RXR 0.0023 0.0017 0.0017
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0023 0.0017 0.0017
Onchocerca volvulus 0.0057 0.0066 0.0151
Echinococcus multilocularis smoothened 0.5623 0.8091 0.8091
Loa Loa (eye worm) hypothetical protein 0.0047 0.0052 0.0052
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0014 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0066 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0137 0.0182 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0023 0.0017 0.0017
Echinococcus granulosus tumor protein p63 0.0329 0.0459 0.0459
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0326 0.0454 1
Mycobacterium ulcerans recombinase A 0.012 0.0158 0.2052
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0041 0.0044 0.0044
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0005 0.0005
Trypanosoma brucei oligopeptidase b 0.0241 0.0332 0.2166
Toxoplasma gondii hypothetical protein 0.0241 0.0332 0.2166
Giardia lamblia Alanyl dipeptidyl peptidase 0.0241 0.0332 0.7126
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0002 0.0002
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0073 0.0365
Onchocerca volvulus 0.0029 0.0027 0.0061
Brugia malayi nuclear receptor NHR-88 0.0023 0.0017 0.0017
Brugia malayi Bromodomain containing protein 0.0035 0.0035 0.0035
Brugia malayi prolyl oligopeptidase family protein 0.0241 0.0332 0.0332
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0454 0.6654
Loa Loa (eye worm) hypothetical protein 0.0137 0.0181 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0137 0.0182 0.0182
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Onchocerca volvulus Peroxidase homolog 0.0029 0.0027 0.0061
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0119 0.0119
Loa Loa (eye worm) blistered cuticle protein 3 0.0029 0.0027 0.0027
Echinococcus granulosus potassium voltage gated channel subfamily H 0.004 0.0042 0.0042
Loa Loa (eye worm) CXXC zinc finger family protein 0.0022 0.0017 0.0017
Entamoeba histolytica prolyl oligopeptidase family protein 0.0241 0.0332 0.7025
Onchocerca volvulus Peroxidase homolog 0.0029 0.0027 0.0061
Schistosoma mansoni hypothetical protein 0.0318 0.0443 0.0443
Schistosoma mansoni hypothetical protein 0.0089 0.0112 0.0112
Echinococcus multilocularis frizzled 5 0.0253 0.035 0.035
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0054 0.0054
Brugia malayi hypothetical protein 0.0016 0.0008 0.0008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0119 0.0119
Schistosoma mansoni transcription factor LCR-F1 0.0114 0.0148 0.0148
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0089 0.0112 0.0112
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0029 0.0062
Treponema pallidum recombinase A 0.012 0.0158 0.2031
Schistosoma mansoni hypothetical protein 0.0137 0.0182 0.0182
Mycobacterium leprae Conserved hypothetical protein 0.1271 0.1816 1
Brugia malayi Transient-receptor-potential like protein 0.0044 0.0049 0.0049
Onchocerca volvulus Chorion peroxidase homolog 0.0029 0.0027 0.0061
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0023 0.0017 0.0017
Schistosoma mansoni frizzled-like receptor 0.0137 0.0182 0.0182
Leishmania major oligopeptidase b 0.0241 0.0332 0.2166
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0029 0.0029
Brugia malayi Fz domain containing protein 0.0116 0.0152 0.0152
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0021 0.0586
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.004 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Loa Loa (eye worm) twinkle helicase 0.0123 0.0162 0.0162
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0132 0.0174 0.0174
Echinococcus multilocularis lamin dm0 0.0057 0.0066 0.0066
Schistosoma mansoni loxhd1 0.0022 0.0016 0.0016
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0044 0.0639
Schistosoma mansoni ap endonuclease 0.0041 0.0044 0.0044
Brugia malayi Animal haem peroxidase family protein 0.0029 0.0027 0.0027
Echinococcus multilocularis cpg binding protein 0.0024 0.0019 0.0019
Schistosoma mansoni microtubule-associated protein tau 0.1508 0.2158 0.2158
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0042 0.0618
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0016 0.0454
Echinococcus multilocularis Niemann Pick C1 protein 0.0157 0.0211 0.0211
Entamoeba histolytica hypothetical protein 0.0114 0.0148 0.2542
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0431 0.0606 0.3176
Entamoeba histolytica hypothetical protein, conserved 0.0241 0.0332 0.7025
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0017 0.0017
Loa Loa (eye worm) beta-lactamase 0.004 0.0042 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0241 0.0332 0.2166
Toxoplasma gondii cell-cycle-associated protein kinase, putative 0.0119 0.0157 0.0946
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0042 0.0152
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0016 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0023 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0114 0.0148 0.0148
Brugia malayi prolyl oligopeptidase family protein 0.0241 0.0332 0.0332
Echinococcus multilocularis short transient receptor potential channel 6 0.0077 0.0096 0.0096
Brugia malayi Steroid receptor seven-up type 2 0.0023 0.0017 0.0017
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0241 0.0332 0.0332
Schistosoma mansoni apoptosis regulator bax 0.0089 0.0112 0.0112
Entamoeba histolytica prolyl oligopeptidase family protein 0.0241 0.0332 0.7025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0119 0.0119
Schistosoma mansoni secreted frizzled-related protein 0.0116 0.0152 0.0152
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0016 0.0016
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0017 0.0017
Schistosoma mansoni rab6-interacting 0.0022 0.0016 0.0016
Echinococcus granulosus Protein patched homolog 1 0.0047 0.0052 0.0052
Onchocerca volvulus 0.0029 0.0027 0.0061
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0011 0.0001 0.0001
Echinococcus granulosus lamin dm0 0.0057 0.0066 0.0066
Schistosoma mansoni wnt inhibitor frzb2 0.0116 0.0152 0.0152
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0001 0.0001
Plasmodium falciparum peptidase, putative 0.0241 0.0332 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0066 0.008 0.008
Echinococcus multilocularis frizzled 10 0.0253 0.035 0.035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0023 0.0017 0.0017
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0053 0.0226
Schistosoma mansoni hypothetical protein 0.0479 0.0675 0.0675
Brugia malayi RNA recognition motif domain containing protein 0.0069 0.0084 0.0084
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0029 0.0029
Brugia malayi prolyl oligopeptidase family protein 0.0241 0.0332 0.0332
Plasmodium vivax SET domain protein, putative 0.0061 0.0073 0.2173
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0021 0.0586
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0041 0.0041
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.1023 0.146 1
Brugia malayi latrophilin 2 splice variant baaae 0.0144 0.0192 0.0192
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0137 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Echinococcus granulosus secreted frizzled protein 5 0.0116 0.0152 0.0152
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0053 0.0774
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0137 0.0182 0.0182
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0069 0.0084 0.0084
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0241 0.0332 0.2166
Brugia malayi beta-lactamase 0.004 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0017
Schistosoma mansoni rab6-interacting 0.0022 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0048 0.0054 0.0054
Schistosoma mansoni transient receptor potential channel 0.0115 0.0151 0.0151
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0042 0.0618
Echinococcus multilocularis lamin 0.0057 0.0066 0.0066
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0119 0.0119
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0016 0.0454
Brugia malayi Pre-SET motif family protein 0.0061 0.0073 0.0073
Brugia malayi nuclear receptor RXR 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Plasmodium falciparum histone acetyltransferase GCN5 0.0044 0.0047 0.1394
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Schistosoma mansoni lamin 0.0057 0.0066 0.0066
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0041 0.0041
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0241 0.0332 0.0332
Trypanosoma cruzi hypothetical protein, conserved 0.0241 0.0332 0.2166
Echinococcus multilocularis secreted frizzled protein 0.0116 0.0152 0.0152
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0041 0.0041
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0053 0.0053
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0042 0.0042
Giardia lamblia Alanyl dipeptidyl peptidase 0.0241 0.0332 0.7126
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0137 0.0182 0.0182
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0066 0.008 0.008
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0159 0.0214 0.0318
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0029
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0023 0.0017 0.0017
Echinococcus granulosus voltage gated potassium channel 0.0014 0.0005 0.0005
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.1023 0.146 0.146
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0257 0.0354 0.0579
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.0332 0.4864
Onchocerca volvulus 0.004 0.0042 0.0097
Trichomonas vaginalis set domain proteins, putative 0.0484 0.0683 1
Brugia malayi Pre-SET motif family protein 0.0426 0.0598 0.0598
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0084 0.0084
Loa Loa (eye worm) animal heme peroxidase 0.0029 0.0027 0.0027
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0241 0.0332 0.2166
Echinococcus granulosus transient receptor potential ion channel A 0.0109 0.0142 0.0142
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0241 0.0332 0.0332
Trypanosoma cruzi oligopeptidase b 0.0241 0.0332 0.2166
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0482 0.0679 0.0679
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0066 0.008 0.008
Loa Loa (eye worm) latrophilin receptor protein 2 0.0066 0.008 0.008
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0061 0.0073 0.0073
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0253 0.035 0.035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0023 0.0017 0.0017
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0089 0.0112 0.0112
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0426 0.0598 0.0598
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Echinococcus granulosus cpg binding protein 0.0024 0.0019 0.0019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0023 0.0017 0.0017
Brugia malayi exodeoxyribonuclease III family protein 0.0041 0.0044 0.0044
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0077 0.0077
Plasmodium vivax hypothetical protein, conserved 0.004 0.0042 0.1245
Echinococcus multilocularis short transient receptor potential channel 6 0.0077 0.0096 0.0096
Schistosoma mansoni peroxidasin 0.0029 0.0027 0.0027
Wolbachia endosymbiont of Brugia malayi recombinase A 0.012 0.0158 0.2031
Loa Loa (eye worm) sfrp2 0.0116 0.0152 0.0152
Schistosoma mansoni lipoxygenase 0.0092 0.0117 0.0117
Echinococcus granulosus lamin 0.0057 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0144 0.0192 0.0192
Trypanosoma cruzi DNA repair protein, putative 0.0037 0.0038 0.012
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0042 0.0618
Onchocerca volvulus Peroxidasin homolog 0.0029 0.0027 0.0061
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0037 0.0038 0.012
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0089 0.0112 0.0112
Brugia malayi PHD-finger family protein 0.0031 0.0029 0.0029
Echinococcus granulosus sterol regulatory element binding protein 0.0047 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus frizzled 0.0253 0.035 0.035
Loa Loa (eye worm) apoptosis regulator protein 0.0089 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0022
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0159 0.0214 0.3047
Loa Loa (eye worm) RNA binding protein 0.0069 0.0084 0.0084
Schistosoma mansoni hypothetical protein 0.0089 0.0112 0.0112
Echinococcus multilocularis Dipeptidyl peptidase 9 0.1023 0.146 0.146
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0454 0.6654
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0028 0.0028
Schistosoma mansoni steroid hormone receptor ad4bp 0.0023 0.0017 0.0017
Plasmodium falciparum phd finger protein, putative 0.0031 0.0029 0.0855
Echinococcus granulosus acylamino acid releasing enzyme 0.0241 0.0332 0.0332
Trypanosoma cruzi oligopeptidase b 0.0241 0.0332 0.2166
Onchocerca volvulus 0.0023 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Echinococcus granulosus intermediate filament protein 0.0057 0.0066 0.0066
Echinococcus multilocularis geminin 0.0479 0.0675 0.0675
Echinococcus multilocularis tumor protein p63 0.0329 0.0459 0.0459
Brugia malayi TAR-binding protein 0.0069 0.0084 0.0084
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0162 0.0218 0.0218
Onchocerca volvulus 0.004 0.0042 0.0097
Brugia malayi Animal haem peroxidase family protein 0.0029 0.0027 0.0027
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus dnaJ subfamily B 0.0318 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0049
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0114 0.0148 0.0148
Schistosoma mansoni transient receptor potential channel 0.0077 0.0096 0.0096
Onchocerca volvulus 0.0022 0.0016 0.0037
Loa Loa (eye worm) pigment dispersing factor receptor c 0.021 0.0287 0.0287
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0029 0.0029
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0023 0.0017 0.0017
Leishmania major hypothetical protein, conserved 0.004 0.0042 0.0152
Echinococcus multilocularis sterol regulatory element binding protein 0.0047 0.0052 0.0052
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0053 0.0226
Echinococcus granulosus prolyl endopeptidase 0.0241 0.0332 0.0332
Schistosoma mansoni polycystin 1-related 0.0022 0.0016 0.0016
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3469 0.4986 0.9169
Schistosoma mansoni hypothetical protein 0.0031 0.0029 0.0029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0073 0.0073
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0041 0.0044 0.0003
Schistosoma mansoni patched 1 0.0047 0.0052 0.0052
Echinococcus multilocularis Niemann Pick C1 protein 0.011 0.0143 0.0143
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0023 0.0017 0.0017
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0023 0.0017 0.0017
Trypanosoma cruzi DNA repair protein, putative 0.0037 0.0038 0.012
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0023 0.0017 0.0017
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0028 0.0028
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0162 0.0218 0.0218
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0066 0.0079 0.0079
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0089 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0022 0.0016 0.0016
Echinococcus multilocularis microtubule associated protein 2 0.1508 0.2158 0.2158
Echinococcus multilocularis transient receptor potential gamma protein 0.0115 0.0151 0.0151
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0014 0.0005 0.0005
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0241 0.0332 0.2166
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0017
Brugia malayi photoreceptor-specific nuclear receptor 0.0023 0.0017 0.0017
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0016 0.0016
Echinococcus multilocularis acylamino acid releasing enzyme 0.0241 0.0332 0.0332
Echinococcus granulosus transient receptor potential gamma protein 0.0115 0.0151 0.0151
Brugia malayi Blistered cuticle protein 3 0.0029 0.0027 0.0027
Echinococcus multilocularis protein patched 0.0047 0.0052 0.0052
Echinococcus granulosus short transient receptor potential channel 6 0.0077 0.0096 0.0096
Loa Loa (eye worm) MH2 domain-containing protein 0.0133 0.0176 0.0176
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0159 0.0214 0.0968
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0069 0.0069
Onchocerca volvulus 0.004 0.0042 0.0097
Brugia malayi Muscleblind-like protein 0.0482 0.0679 0.0679
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0052 0.0765
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0073 0.0073
Schistosoma mansoni cpg binding protein 0.0022 0.0017 0.0017

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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