Detailed information for compound 982615

Basic information

Technical information
  • TDR Targets ID: 982615
  • Name: 4-chloro-2-[(2-hydroxyphenyl)methyl]phenol
  • MW: 234.678 | Formula: C13H11ClO2
  • H donors: 2 H acceptors: 2 LogP: 3.76 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(c(c1)Cc1ccccc1O)O
  • InChi: 1S/C13H11ClO2/c14-11-5-6-13(16)10(8-11)7-9-3-1-2-4-12(9)15/h1-6,8,15-16H,7H2
  • InChiKey: JFICBMAELAHNNQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4-chloro-2-(2-hydroxybenzyl)phenol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) endoplasmin 0.0055 0.0363 0.0363
Trypanosoma brucei heat shock protein, putative 0.0055 0.0363 0.0493
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Brugia malayi sulfakinin receptor protein 0.0015 0.0036 0.0036
Schistosoma mansoni zinc finger protein 0.002 0.0078 0.0042
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0069 0.0068
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.0036 0.0035
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0447 0.2428
Loa Loa (eye worm) hypothetical protein 0.0023 0.0097 0.0097
Brugia malayi hypothetical protein 0.0015 0.0036 0.0036
Schistosoma mansoni rab6-interacting 0.0024 0.0107 0.0072
Brugia malayi Endoplasmin precursor 0.0055 0.0363 0.0363
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0211 0.1626 0.1596
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0211 0.1626 0.1626
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.0036 0.0035
Onchocerca volvulus 0.0033 0.0178 0.0143
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0036 0.0035
Trypanosoma brucei heat shock protein, putative 0.0055 0.0363 0.0493
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0211 0.1626 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0211 0.1626 0.1596
Echinococcus multilocularis thyroid hormone receptor alpha 0.0043 0.0261 0.0259
Brugia malayi AKH receptor 0.0015 0.0036 0.0036
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.0635 0.0634
Brugia malayi putative neuropeptide receptor NPR1 0.0015 0.0036 0.0036
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0139 0.1043 0.1042
Brugia malayi conserved hypotetical protein 0.002 0.0078 0.0078
Plasmodium falciparum endoplasmin, putative 0.004 0.024 0.1098
Echinococcus granulosus sodium and chloride dependent glycine 0.0211 0.1626 0.1625
Schistosoma mansoni nuclear hormone receptor 0.002 0.0078 0.0042
Schistosoma mansoni loxhd1 0.0024 0.0107 0.0072
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0069 0.0052
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0388 0.3063 0.3062
Onchocerca volvulus 0.0024 0.0107 0.0072
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0043 0.0261 0.0261
Brugia malayi Serotonin receptor 0.0015 0.0036 0.0036
Echinococcus multilocularis Ankyrin 0.0018 0.0056 0.0055
Schistosoma mansoni cpg binding protein 0.0037 0.0212 0.0176
Brugia malayi nuclear hormone receptor 0.002 0.0078 0.0078
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0211 0.1626 1
Brugia malayi Doublecortin family protein 0.0024 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0078
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0261 0.0226
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0036 0.0035
Echinococcus granulosus fmrfamide receptor 0.0015 0.0036 0.0035
Schistosoma mansoni hypothetical protein 0.0205 0.1574 0.1544
Schistosoma mansoni hypothetical protein 0.0024 0.0107 0.0072
Schistosoma mansoni thyroid hormone receptor 0.0043 0.0261 0.0226
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Trichomonas vaginalis heat shock protein, putative 0.0055 0.0363 1
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0211 0.1626 0.1625
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus death domain containing protein 0.0017 0.0055 0.0054
Entamoeba histolytica heat shock protein 90, putative 0.0055 0.0363 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0387 0.0386
Leishmania major C-8 sterol isomerase-like protein 0.0835 0.6688 1
Brugia malayi hypothetical protein 0.0043 0.0267 0.0266
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0261 0.0261
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0078 0.0076
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0036 0.0035
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0043 0.0261 0.0226
Loa Loa (eye worm) heat shock protein 75 0.0037 0.0212 0.0212
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0043 0.0261 0.0261
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0015 0.0036 0.0036
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0835 0.6688 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0069 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0043 0.0261 0.0261
Loa Loa (eye worm) solute carrier family 6 member 4 0.1244 1 1
Echinococcus granulosus serotonin receptor 0.0015 0.0036 0.0035
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0055 0.0055
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0363 0.0493
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0036 0.0035
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0055 0.0054
Schistosoma mansoni heat shock protein 0.0037 0.0212 0.0177
Brugia malayi Dopamine receptor protein 1 0.0015 0.0036 0.0036
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.0036 0.0036
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0363 0.0493
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Trypanosoma brucei heat shock protein 90, putative 0.0055 0.0363 0.0493
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0069 0.0069
Brugia malayi hypothetical protein 0.0286 0.223 0.223
Echinococcus granulosus serotonin transporter 0.1244 1 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0015 0.0036 0.0036
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.0107 0.0246
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.0036 0.0035
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0211 0.1626 0.1625
Brugia malayi ORL1-like opioid receptor 0.0015 0.0036 0.0036
Echinococcus granulosus g protein coupled receptor 0.0015 0.0036 0.0035
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Schistosoma mansoni intermediate filament proteins 0.0033 0.0178 0.0143
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0078 0.0042
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0097 0.0096
Giardia lamblia Grp94/Hsp90 0.0052 0.0335 0.5748
Brugia malayi Nuclear hormone receptor E75 0.002 0.0078 0.0078
Brugia malayi hypothetical protein 0.0015 0.0036 0.0036
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0261 0.0261
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Brugia malayi hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0427 0.3376 0.3376
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0078
Echinococcus granulosus g protein coupled receptor 0.0015 0.0036 0.0035
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0067 0.0455 0.0454
Plasmodium falciparum heat shock protein 90 0.0055 0.0363 0.1888
Echinococcus granulosus neuropeptide receptor A26 0.0015 0.0036 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Echinococcus multilocularis FTZ F1 alpha 0.0043 0.0261 0.0259
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0107 0.0246
Schistosoma mansoni amine GPCR 0.0352 0.2768 0.2742
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0036 0.0035
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0043 0.0261 0.0259
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.6673 0.6673
Brugia malayi neuropeptide F receptor 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Onchocerca volvulus Protein ultraspiracle homolog 0.0043 0.0261 0.0226
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.1083 0.1083
Brugia malayi G-protein coupled receptor 0.0015 0.0036 0.0036
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0211 0.1626 0.1626
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0015 0.0036 0.0036
Echinococcus multilocularis musashi 0.0033 0.0178 0.0177
Echinococcus granulosus lamin dm0 0.0033 0.0178 0.0177
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0055 0.0054
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0035 0.0035
Trypanosoma cruzi heat shock protein 90, putative 0.0023 0.0102 0.0101
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0107 0.0106
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0195 0.0195
Echinococcus granulosus neuropeptide receptor 0.0015 0.0036 0.0035
Schistosoma mansoni polycystin 1-related 0.0024 0.0107 0.0072
Schistosoma mansoni sodium-dependent amino acid transporter 0.0211 0.1626 0.1596
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0069 0.0068
Onchocerca volvulus 0.0043 0.0261 0.0226
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Brugia malayi Steroid receptor seven-up type 2 0.0043 0.0261 0.0261
Trypanosoma brucei heat shock protein, putative 0.0055 0.0363 0.0493
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0261 0.0226
Brugia malayi larval opioid receptor 0.0015 0.0036 0.0036
Schistosoma mansoni sodium/chloride dependent transporter 0.0211 0.1626 0.1596
Plasmodium vivax heat shock protein, putative 0.021 0.1615 0.9928
Onchocerca volvulus 0.0024 0.0107 0.0072
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Echinococcus granulosus dnaJ subfamily B 0.0494 0.392 0.392
Mycobacterium ulcerans heat shock protein 90 0.0052 0.0335 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0036 0.0035
Brugia malayi Tachykinin-like peptides receptor 99D 0.0015 0.0036 0.0036
Onchocerca volvulus 0.0211 0.1626 0.1596
Brugia malayi Nuclear hormone receptor E75 0.002 0.0078 0.0078
Echinococcus granulosus cpg binding protein 0.0037 0.0212 0.021
Plasmodium vivax heat shock protein 90, putative 0.0037 0.0212 0.0921
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Trypanosoma cruzi heat shock protein 90, putative 0.0055 0.0363 0.0493
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0036 0.0035
Schistosoma mansoni coup transcription factor 0.0043 0.0261 0.0226
Echinococcus multilocularis serotonin transporter 0.1244 1 1
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0042 0.004
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.0036 0.0035
Entamoeba histolytica hypothetical protein 0.0043 0.0267 0.36
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0211 0.1626 0.1625
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0043 0.0261 0.0261
Brugia malayi hypothetical protein 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0043 0.0261 0.0261
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0211 0.1626 0.1596
Echinococcus multilocularis sodium and chloride dependent glycine 0.0211 0.1626 0.1625
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0211 0.1626 0.1626
Trypanosoma brucei heat shock protein 84, putative 0.0037 0.0212 0.0267
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0043 0.0261 0.0261
Trypanosoma brucei C-8 sterol isomerase, putative 0.0835 0.6688 1
Plasmodium vivax amine transporter, putative 0.0211 0.1626 1
Entamoeba histolytica hypothetical protein 0.0043 0.0267 0.36
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0052 0.0335 1
Loa Loa (eye worm) hypothetical protein 0.0211 0.1626 0.1626
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0267 0.0265
Trichomonas vaginalis heat shock protein, putative 0.0052 0.0335 0.8533
Brugia malayi Protein kinase domain containing protein 0.0017 0.0055 0.0055
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.0036 0.0035
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0211 0.1626 0.5
Echinococcus granulosus allatostatin A receptor 0.0015 0.0036 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0043 0.0261 0.0261
Schistosoma mansoni hypothetical protein 0.0043 0.0267 0.0232
Onchocerca volvulus 0.0033 0.0178 0.0143
Echinococcus granulosus RUN 0.0024 0.0107 0.0106
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0036 0.0035
Schistosoma mansoni lipoxygenase 0.0067 0.0455 0.0421
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.0036 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0211 0.1626 0.1626
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0036 0.0035
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0043 0.0261 0.0259
Brugia malayi hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus heat shock protein 90 0.0047 0.0298 0.0297
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0078 0.0076
Echinococcus multilocularis RUN 0.0024 0.0107 0.0106
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0037 0.0212 0.0177
Brugia malayi Uncoordinated protein 44 0.0017 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0018 0.0056 0.0056
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0036 0.0035
Brugia malayi nuclear receptor NHR-88 0.0043 0.0261 0.0261
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0036 0.0035
Echinococcus granulosus hypothetical protein 0.0015 0.0036 0.0035
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.0036 0.0035
Trichomonas vaginalis heat shock protein, putative 0.0052 0.0335 0.8533
Echinococcus multilocularis allatostatin A receptor 0.0015 0.0036 0.0035
Loa Loa (eye worm) steroid hormone receptor 0.0043 0.0261 0.0261
Echinococcus granulosus heat shock protein 90 0.0055 0.0363 0.0362
Loa Loa (eye worm) hypothetical protein 0.0286 0.223 0.223
Schistosoma mansoni heat shock protein 0.0055 0.0363 0.0328
Onchocerca volvulus Bile acid receptor homolog 0.0043 0.0261 0.0226
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Onchocerca volvulus 0.002 0.0078 0.0042
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0069 0.0068
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Trichomonas vaginalis heat shock protein, putative 0.004 0.024 0.345
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0178 0.0178
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0267 0.0265
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0078
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.0036 0.0035
Plasmodium vivax heat shock protein 86, putative 0.0055 0.0363 0.1888
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0043 0.0261 0.0261
Schistosoma mansoni rab6-interacting 0.0024 0.0107 0.0072
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0261 0.0259
Trypanosoma brucei heat shock protein 90, putative 0.0055 0.0363 0.0493
Entamoeba histolytica hypothetical protein 0.0043 0.0267 0.36
Brugia malayi heat shock protein 90 0.0055 0.0363 0.0363
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0043 0.0261 0.0259
Brugia malayi Cytochrome P450 family protein 0.0015 0.0035 0.0035
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.6673 0.6661
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0078 0.0042
Echinococcus granulosus somatostatin receptor 0.0015 0.0036 0.0035
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0037 0.0212 0.0211
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.392 0.392
Loa Loa (eye worm) hypothetical protein 0.0032 0.0173 0.0173
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0018 0.0056 0.002
Brugia malayi G protein-coupled receptor 0.0015 0.0036 0.0036
Brugia malayi hypothetical protein 0.0211 0.1626 0.1626
Plasmodium falciparum heat shock protein 90, putative 0.021 0.1615 0.9928
Brugia malayi intermediate filament protein 0.0033 0.0178 0.0178
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0052 0.0335 0.5
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0043 0.0261 0.0226
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0261 0.0259
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0211 0.1626 0.1625
Echinococcus granulosus FTZ F1 alpha 0.0043 0.0261 0.0259
Onchocerca volvulus 0.0058 0.0387 0.0352
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0078 0.0076
Loa Loa (eye worm) hypothetical protein 0.0015 0.0037 0.0037
Schistosoma mansoni biogenic amine (5HT) receptor 0.0388 0.3063 0.3038
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0043 0.0261 0.0259
Onchocerca volvulus 0.0035 0.0195 0.016
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.0036 0.0035
Echinococcus multilocularis serotonin receptor 0.0015 0.0036 0.0035
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0107 0.0106
Loa Loa (eye worm) norepinephrine transporter 0.1244 1 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0107 0.0106
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0069 0.0068
Brugia malayi nuclear receptor RXR 0.0023 0.0097 0.0097
Brugia malayi hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0107 0.0107
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0178 0.0178
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0078 0.0076
Loa Loa (eye worm) hypothetical protein 0.0023 0.0097 0.0097
Brugia malayi hypothetical protein 0.0024 0.0107 0.0107
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.0036 0.0035
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.0298 0.0396
Brugia malayi ecdysone receptor 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0043 0.0261 0.0261
Brugia malayi Cytochrome P450 family protein 0.0015 0.0035 0.0035
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0097 0.0096
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0036 0.0035
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0015 0.0036 0.0036
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0211 0.1626 0.1596
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus lamin 0.0033 0.0178 0.0177
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0261 0.0261
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0015 0.0036 0.0036
Brugia malayi Melatonin receptor type 1A 0.0015 0.0036 0.0036
Brugia malayi nuclear receptor NHR-67 0.002 0.0078 0.0078
Schistosoma mansoni heat shock protein 0.0055 0.0363 0.0328
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0043 0.0261 0.0259
Echinococcus multilocularis cpg binding protein 0.0037 0.0212 0.021
Echinococcus multilocularis geminin 0.0205 0.1574 0.1573
Brugia malayi Dopamine receptor 0.0015 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0494 0.392 0.3898
Toxoplasma gondii heat shock protein 90, putative 0.0055 0.0363 0.1888
Echinococcus multilocularis endoplasmin 0.0052 0.0335 0.0334
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0036 0.0035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0261 0.0259
Toxoplasma gondii hypothetical protein 0.0211 0.1626 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.0036 0.0035
Schistosoma mansoni RAR-like nuclear receptor 0.0043 0.0261 0.0226
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0036 0.0035
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0211 0.1626 0.1596
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0261 0.0259
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0211 0.1626 0.1626
Loa Loa (eye worm) hypothetical protein 0.0023 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0023 0.0097 0.0097
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0511 0.0477
Loa Loa (eye worm) hypothetical protein 0.0043 0.0261 0.0261
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Trypanosoma brucei heat shock protein, putative 0.0055 0.0363 0.0493
Brugia malayi hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0078
Brugia malayi nuclear receptor NHR-88 0.002 0.0078 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0043 0.0261 0.0261
Loa Loa (eye worm) serotonin transporter b 0.1244 1 1
Schistosoma mansoni nuclear hormone receptor 0.002 0.0078 0.0042
Echinococcus multilocularis serotonin receptor 0.0015 0.0036 0.0035
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Plasmodium falciparum amino acid transporter, putative 0.0211 0.1626 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0078
Schistosoma mansoni retinoic acid receptor RXR 0.0162 0.1226 0.1195
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.223 0.2229
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0211 0.1626 0.1596
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0055 0.0055
Brugia malayi Hsp90 protein 0.0037 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0043 0.0261 0.0261
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0001 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0036 0.0035
Brugia malayi RE15519p 0.0015 0.0036 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0043 0.0261 0.0261
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0056 0.0056
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1244 1 1
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0097 0.0097
Echinococcus multilocularis heat shock protein 90 0.0055 0.0363 0.0362
Loa Loa (eye worm) hypothetical protein 0.0211 0.1626 0.1626
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.0036 0.0036
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0211 0.1626 0.1596
Brugia malayi steroid hormone receptor 0.0043 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Entamoeba histolytica hypothetical protein 0.0043 0.0267 0.36
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0043 0.0261 0.0259
Brugia malayi ecdysteroid receptor 0.0043 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus multilocularis lamin 0.0033 0.0178 0.0177
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0078 0.0078
Brugia malayi neuropeptide F receptor 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0055 0.0019
Loa Loa (eye worm) hypothetical protein 0.0024 0.0107 0.0107
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0261 0.0261
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0043 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0078
Brugia malayi G protein-coupled receptor F59B2.13 0.0015 0.0036 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Echinococcus granulosus microtubule associated protein 2 0.0833 0.6673 0.6673
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.0635 0.0634
Schistosoma mansoni cpg binding protein 0.0037 0.0212 0.0176
Echinococcus multilocularis sodium and chloride dependent glycine 0.0211 0.1626 0.1625
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0036 0.0035
Entamoeba histolytica heat shock protein 90, putative 0.0055 0.0363 1
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0267 0.0232
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0043 0.0261 0.0226
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0036 0.0035
Schistosoma mansoni cpg binding protein 0.0035 0.0195 0.016
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0043 0.0261 0.0261
Echinococcus multilocularis sex peptide receptor 0.0015 0.0036 0.0035
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0097 0.0062
Echinococcus granulosus sex peptide receptor 0.0015 0.0036 0.0035
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0211 0.1626 0.1626
Schistosoma mansoni endoplasmin 0.0055 0.0363 0.0328
Brugia malayi hypothetical protein 0.002 0.0078 0.0078
Echinococcus granulosus Ankyrin 0.0018 0.0056 0.0055
Trypanosoma cruzi heat shock protein, putative 0.0037 0.0212 0.0267
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Brugia malayi nuclear hormone receptor 0.0043 0.0261 0.0261
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.0036 0.0035
Toxoplasma gondii heat shock protein 75, putative 0.0037 0.0212 0.0921
Echinococcus granulosus ecdysone induced protein 78C 0.0043 0.0261 0.0259
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0037 0.0212 0.0211
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.0036 0.0035
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0043 0.0261 0.0259
Echinococcus multilocularis somatostatin receptor 0.0015 0.0036 0.0035
Brugia malayi tailless protein 0.002 0.0078 0.0078
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0835 0.6688 0.6688
Schistosoma mansoni hypothetical protein 0.0058 0.0387 0.0352
Toxoplasma gondii Hsp90 domain-containing protein 0.021 0.1615 0.9928
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.1083 0.1083
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.0036 0.0035
Onchocerca volvulus 0.0211 0.1626 0.1596
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0097 0.0097
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0211 0.1626 1
Schistosoma mansoni nuclear receptor 0.002 0.0078 0.0042
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0036 0.0035
Brugia malayi hypothetical protein 0.0015 0.0036 0.0036
Trypanosoma cruzi Heat shock protein 83, putative 0.0055 0.0363 0.0493
Loa Loa (eye worm) hypothetical protein 0.0211 0.1626 0.1626
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0078 0.0078
Brugia malayi follicle stimulating hormone receptor 0.0015 0.0036 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Trypanosoma brucei heat shock protein, putative 0.0055 0.0363 0.0493
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0052 0.0335 0.5
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0035 0.0035
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0069 0.0052
Echinococcus multilocularis ecdysone induced protein 78C 0.0043 0.0261 0.0259
Loa Loa (eye worm) hypothetical protein 0.0043 0.0261 0.0261
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0261 0.0261
Echinococcus granulosus biogenic amine 5HT receptor 0.0388 0.3063 0.3062
Loa Loa (eye worm) hypothetical protein 0.0023 0.0097 0.0097
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0036 0.0035
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0363 0.0493
Schistosoma mansoni endoplasmin 0.0055 0.0363 0.0328
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0107 0.0106
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0036 0.0036
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0078 0.0076
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.0036 0.0035
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0036 0.0036
Trypanosoma brucei Heat shock protein 83, putative 0.0055 0.0363 0.0493
Brugia malayi hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0078 0.0078
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0078 0.0078
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0043 0.0261 0.0226
Schistosoma mansoni nuclear receptor 0.002 0.0078 0.0042
Echinococcus granulosus neuropeptide receptor 0.0015 0.0036 0.0035
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0107 0.0107
Trypanosoma cruzi heat shock protein 90, putative 0.0047 0.0298 0.0396
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0162 0.1226 0.1225
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0078 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0261 0.0261
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0055 0.0054
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0078 0.0076
Echinococcus multilocularis heat shock protein 0.0055 0.0363 0.0362
Brugia malayi isocitrate dehydrogenase 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0078
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0078 0.0042
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0211 0.1626 0.1596
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0067 0.0455 0.0454
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Loa Loa (eye worm) hypothetical protein 0.0017 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0211 0.1626 0.1626
Brugia malayi GnHR receptor homolog 0.0015 0.0036 0.0036
Giardia lamblia Heat shock protein HSP 90-alpha 0.0055 0.0363 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0078 0.0076
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Brugia malayi hypothetical protein 0.0023 0.0097 0.0097
Echinococcus granulosus geminin 0.0205 0.1574 0.1573
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.0036 0.0035
Plasmodium falciparum transporter, putative 0.0211 0.1626 1
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0052 0.0335 0.0452
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0211 0.1626 0.1626
Trichomonas vaginalis endoplasmin, putative 0.004 0.024 0.345
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0036 0.0035
Onchocerca volvulus Netrin receptor homolog 0.0017 0.0055 0.0019
Schistosoma mansoni lipoxygenase 0.0024 0.0107 0.0072
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0078 0.0076
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0211 0.1626 0.1625
Schistosoma mansoni lamin 0.0033 0.0178 0.0143
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0036 0.0035
Leishmania major heat shock protein, putative 0.0037 0.0212 0.0267
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.0036 0.0035
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0036 0.0035
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0036 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0043 0.0261 0.0261
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0043 0.0261 0.0261
Echinococcus granulosus neuropeptide s receptor 0.0015 0.0036 0.0035
Schistosoma mansoni steroid hormone receptor ad4bp 0.0043 0.0261 0.0226
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.0036 0.0035
Echinococcus granulosus intermediate filament protein 0.0033 0.0178 0.0177
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.0036 0.0036
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Brugia malayi putative neuropeptide receptor 0.0015 0.0036 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0298 0.655
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0043 0.0261 0.0261
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0107 0.0106
Echinococcus granulosus sodium and chloride dependent glycine 0.0211 0.1626 0.1625
Echinococcus multilocularis orexin receptor type 2 0.0015 0.0036 0.0035
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0069 0.0052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0205 0.1574 0.1544
Schistosoma mansoni lamin 0.0033 0.0178 0.0143
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0107 0.0106
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0043 0.0261 0.0226
Loa Loa (eye worm) heat shock protein 90 0.0055 0.0363 0.0363
Loa Loa (eye worm) hypothetical protein 0.0033 0.0178 0.0178
Brugia malayi CXXC zinc finger family protein 0.0035 0.0195 0.0195
Loa Loa (eye worm) DR-78 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0043 0.0261 0.0261
Trypanosoma brucei heat shock protein, putative 0.0055 0.0363 0.0493
Trypanosoma brucei heat shock protein, putative 0.0055 0.0363 0.0493
Echinococcus granulosus g protein coupled receptor 0.0015 0.0036 0.0035
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0835 0.6688 0.6688
Brugia malayi G-protein coupled receptor 0.0015 0.0036 0.0036
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Toxoplasma gondii heat shock protein HSP90 0.0055 0.0363 0.1888
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0043 0.0261 0.0226
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0036 0.0036
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0211 0.1626 0.1626
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.0036 0.0035
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0078 0.0076
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0015 0.0036 0.0036
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0055 0.0054
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0078 0.0042
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0047 0.0298 0.0297
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0036 0.0035
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0211 0.1626 0.1625
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0036 0.0035
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0211 0.1626 0.1625
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0036 0.0036
Echinococcus multilocularis neuropeptide receptor A26 0.0015 0.0036 0.0035
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.0036 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0261 0.0261
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0078 0.0076
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0078
Echinococcus multilocularis neuropeptide s receptor 0.0015 0.0036 0.0035
Echinococcus multilocularis lamin dm0 0.0033 0.0178 0.0177
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0037 0.0037
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0069 0.0052
Schistosoma mansoni thyroid hormone receptor 0.0043 0.0261 0.0226
Brugia malayi Dopamine receptor protein 2 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0078
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0042 0.004
Onchocerca volvulus 0.002 0.0078 0.0042
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0043 0.0261 0.0259
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0078 0.0042
Schistosoma mansoni survival motor neuron protein 0.0058 0.0387 0.0352
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0097 0.0062
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus heat shock protein 0.0055 0.0363 0.0362
Brugia malayi photoreceptor-specific nuclear receptor 0.0043 0.0261 0.0261
Treponema pallidum sodium- and chloride- dependent transporter 0.1244 1 1
Echinococcus granulosus endoplasmin 0.0052 0.0335 0.0334
Schistosoma mansoni hypothetical protein 0.0017 0.0055 0.0019
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.0036 0.0035
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.223 0.2229
Schistosoma mansoni netrin receptor unc5 0.0017 0.0055 0.0019
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0078 0.0078
Brugia malayi nuclear receptor RXR 0.002 0.0078 0.0078
Echinococcus granulosus g-protein coupled receptor 0.0015 0.0036 0.0035
Schistosoma mansoni sodium/chloride dependent transporter 0.1244 1 1
Plasmodium vivax hypothetical protein, conserved 0.0211 0.1626 1
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0036 0.0035
Brugia malayi hypothetical protein 0.0023 0.0097 0.0097
Plasmodium vivax endoplasmin, putative 0.0055 0.0363 0.1888
Onchocerca volvulus 0.0211 0.1626 0.1596
Loa Loa (eye worm) hypothetical protein 0.1244 1 1
Brugia malayi Serotonin receptor 0.0015 0.0036 0.0036
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0078 0.0076
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0069 0.0069
Brugia malayi hypothetical protein 0.0024 0.0107 0.0107
Trypanosoma brucei heat shock protein, putative 0.0055 0.0363 0.0493
Brugia malayi hypothetical protein 0.0015 0.0036 0.0036
Toxoplasma gondii hypothetical protein 0.0211 0.1626 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0069 0.0052
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0069 0.0033
Loa Loa (eye worm) hypothetical protein 0.0043 0.0261 0.0261
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Echinococcus granulosus orexin receptor type 2 0.0015 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.1244 1 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0261 0.0261
Brugia malayi Death domain containing protein 0.0017 0.0055 0.0055
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.1244 1 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0097 0.0097
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0211 0.1626 0.1596
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0056 0.0056
Plasmodium falciparum heat shock protein 90, putative 0.0032 0.0175 0.0682
Brugia malayi MH2 domain containing protein 0.0144 0.1083 0.1083
Leishmania major heat shock protein 83-1 0.0055 0.0363 0.0493
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0069 0.0068
Onchocerca volvulus 0.1244 1 1
Echinococcus multilocularis heat shock protein 90 0.0047 0.0298 0.0297
Brugia malayi hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0211 0.1626 0.1626

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 50 ug ml-1 Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs ChEMBL. 19097894
MIC (functional) = 50 ug ml-1 Antifungal activity against Candida albicans ATCC 10231 after 48 to 72 hrs ChEMBL. 19097894

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.