Detailed information for compound 988009

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 348.481 | Formula: C23H28N2O
  • H donors: 0 H acceptors: 1 LogP: 3.94 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1Cc2c(N1CCCCN1CCCC(C1)c1ccccc1)cccc2
  • InChi: 1S/C23H28N2O/c26-23-17-20-11-4-5-13-22(20)25(23)16-7-6-14-24-15-8-12-21(18-24)19-9-2-1-3-10-19/h1-5,9-11,13,21H,6-8,12,14-18H2
  • InChiKey: ZKPFKNIFSQQQET-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum Octopamine receptor, putative Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum expressed protein Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma mansoni biogenic amine (5HT) receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum ko:K04153 5-hydroxytryptamine (serotonin) receptor 1A, putative Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus granulosus biogenic amine 5HT receptor Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus granulosus biogenic amine 5HT receptor Get druggable targets OG5_133074 All targets in OG5_133074
Echinococcus multilocularis biogenic amine (5HT) receptor Get druggable targets OG5_133074 All targets in OG5_133074
Schistosoma mansoni biogenic amine (5HT) receptor Get druggable targets OG5_133074 All targets in OG5_133074
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Pre-SET motif family protein 0.0033 0.0521 0.0808
Brugia malayi MH2 domain containing protein 0.0117 0.2376 0.4607
Loa Loa (eye worm) hypothetical protein 0.0049 0.0866 0.1729
Loa Loa (eye worm) hypothetical protein 0.0033 0.0524 0.1045
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0127 0.0253
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0267 0.0308
Echinococcus multilocularis serotonin receptor 0.0153 0.3175 0.3155
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.1413 0.2636
Schistosoma mansoni cytochrome P450 0.0022 0.0267 0.0239
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0866 0.1515
Schistosoma mansoni hypothetical protein 0.0015 0.0126 0.0097
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0248 0.0249
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0777 0.1551
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0127 0.0098
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0521 0.0493
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0836 1
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0267 0.0308
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0565 0.0537
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0565 0.0537
Schistosoma mansoni biogenic amine (5HT) receptor 0.046 1 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0127 0.0098
Echinococcus granulosus GPCR family 2 0.0015 0.0126 0.0097
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0267 0.0308
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0484 0.0965
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0267 0.1982
Loa Loa (eye worm) pax transcription factor protein 2 0.0235 0.501 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0866 0.1729
Leishmania major cytochrome p450-like protein 0.0022 0.0267 0.1093
Loa Loa (eye worm) hypothetical protein 0.0153 0.3175 0.6338
Brugia malayi Pre-SET motif family protein 0.0231 0.4922 0.982
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0331 0.1037
Schistosoma mansoni hypothetical protein 0.0015 0.0126 0.0097
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0248 0.195
Brugia malayi acetyltransferase, GNAT family protein 0.0161 0.3362 0.6626
Mycobacterium leprae PROBABLE ATP SYNTHASE A CHAIN ATPB (PROTEIN 6) 0.0221 0.4692 1
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0267 0.0308
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0777 0.075
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0127 0.0098
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0836 0.1092
Schistosoma mansoni biogenic amine (5HT) receptor 0.0153 0.3175 0.3155
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0484 0.2774
Brugia malayi cytochrome P450 0.0022 0.0267 0.0289
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0267 0.0044
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0267 0.0044
Brugia malayi Cytochrome P450 family protein 0.0022 0.0267 0.0289
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0267 0.0044
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0248 0.0942
Loa Loa (eye worm) hypothetical protein 0.0033 0.0521 0.1039
Schistosoma mansoni hypothetical protein 0.0022 0.0267 0.0239
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0267 0.0308
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0267 0.0044
Onchocerca volvulus 0.0235 0.501 0.8784
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0267 0.0308
Schistosoma mansoni hypothetical protein 0.0015 0.0126 0.0097
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.2376 0.4743
Loa Loa (eye worm) acetyltransferase 0.0161 0.3362 0.6711
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0777 0.075
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.2376 0.4743
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0126 0.0097
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0521 0.0493
Schistosoma mansoni ATP synthase F0 subunit 6 0.0221 0.4692 0.4676
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0267 0.0714
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0521 0.0493
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0248 0.0942
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0267 0.0534
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.1413 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.1413 0.1388
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.1413 0.2821
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0484 0.2774
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0267 0.0308
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0331 0.288
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0521 0.5554
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0727 0.07
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0267 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0267 0.0308
Mycobacterium ulcerans F0F1 ATP synthase subunit A 0.0221 0.4692 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0127 0.0098
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0331 0.1588
Loa Loa (eye worm) cytochrome P450 0.0022 0.0267 0.0534
Trichomonas vaginalis set domain proteins, putative 0.0263 0.5631 1
Brugia malayi hypothetical protein 0.0025 0.0331 0.0419
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0267 0.0044
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0836 0.0809
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0231 0.4922 0.9824
Onchocerca volvulus 0.0263 0.5631 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0748 1
Entamoeba histolytica hypothetical protein 0.0035 0.0565 0.272
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.1413 1
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.1413 0.1388
Schistosoma mansoni hypothetical protein 0.0035 0.0565 0.0537
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0248 0.0219
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0267 0.0308
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0565 0.0537
Echinococcus multilocularis biogenic amine (5HT) receptor 0.046 1 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0521 0.0493
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0521 0.0493
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0331 0.3287
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0248 0.0266
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0267 0.0308
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0484 0.0965
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0267 0.0044
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0267 0.1093
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0267 0.0308
Echinococcus multilocularis GPCR, family 2 0.0015 0.0126 0.0097
Schistosoma mansoni hypothetical protein 0.0015 0.0126 0.0097
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0248 0.1709
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0126 0.0097
Schistosoma mansoni hypothetical protein 0.0188 0.3967 0.3949
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0126 0.0252
Leishmania major hypothetical protein, conserved 0.0025 0.0331 0.1588
Schistosoma mansoni hypothetical protein 0.0033 0.0524 0.0496
Echinococcus granulosus histone acetyltransferase KAT2B 0.0157 0.3261 0.3242
Brugia malayi hypothetical protein 0.0035 0.0565 0.0898
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0494 0.0466
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0484 0.1812
Echinococcus multilocularis serotonin receptor 0.0153 0.3175 0.3155
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.0484 0.053
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0267 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0267 0.0308
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0524 0.0814
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0161 0.3362 0.3342
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0836 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0836 0.1092
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0267 0.0308
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0267 0.0308
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0267 0.0044
Schistosoma mansoni hypothetical protein 0.0104 0.2096 0.2073
Echinococcus granulosus geminin 0.0188 0.3967 0.3949
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0777 0.1333
Entamoeba histolytica hypothetical protein 0.0035 0.0565 0.272
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.1413 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0267 0.0044
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0331 0.288
Brugia malayi isocitrate dehydrogenase 0.0015 0.0127 0.0001
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0267 0.0044
Brugia malayi Cytochrome P450 family protein 0.0032 0.0484 0.0732
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0126 0.0097
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0836 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0248 0.0219
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0777 0.075
Brugia malayi Cytochrome P450 family protein 0.0032 0.0484 0.0732
Trypanosoma brucei RNA helicase, putative 0.0104 0.2096 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0521 0.0493
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0267 0.1093
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0127 0.0001
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0267 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0267 0.0308
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0248 0.0942
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0126 0.0097
Mycobacterium tuberculosis Probable ATP synthase a chain AtpB (protein 6) 0.0221 0.4692 1
Leishmania major cytochrome p450-like protein 0.0032 0.0484 0.2774
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0267 0.0308
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0484 0.0965
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0267 0.0044
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0267 0.0044
Loa Loa (eye worm) hypothetical protein 0.0025 0.0331 0.0661
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0331 0.3287
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0777 0.075
Schistosoma mansoni hypothetical protein 0.0188 0.3967 0.3949
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0267 0.0044
Brugia malayi Pax transcription factor protein 2 0.0235 0.501 1
Echinococcus multilocularis 0.0022 0.0267 0.0239
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0331 0.1588
Brugia malayi hypothetical protein 0.0016 0.0137 0.0022
Wolbachia endosymbiont of Brugia malayi ATP synthase F0F1 subunit A 0.0221 0.4692 1
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0267 0.0308
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0248 0.0495
Plasmodium vivax SET domain protein, putative 0.0033 0.0521 0.5554
Entamoeba histolytica hypothetical protein 0.0035 0.0565 0.272
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0748 0.4293
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.1413 0.1388
Entamoeba histolytica hypothetical protein 0.0035 0.0565 0.272
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.1413 1
Schistosoma mansoni ap endonuclease 0.0021 0.0248 0.0219
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0267 0.0044
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0161 0.3362 0.3342
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0127 0.0098
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0267 0.1093
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0267 0.0308
Schistosoma mansoni ap endonuclease 0.0021 0.0248 0.0219
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0267 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0267 0.0308
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0866 0.1515
Brugia malayi Cytochrome P450 family protein 0.0022 0.0267 0.0289
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0267 0.0044
Toxoplasma gondii exonuclease III APE 0.0021 0.0248 0.1709
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0521 0.0493
Echinococcus granulosus biogenic amine 5HT receptor 0.0153 0.3175 0.3155
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0127 0.0098
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0267 0.0239
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0777 0.075
Leishmania major cytochrome p450-like protein 0.0022 0.0267 0.1093
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0727 0.07
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0248 0.0616
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0777 0.075
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0267 0.0044
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.1413 0.6534
Loa Loa (eye worm) hypothetical protein 0.0015 0.0126 0.0252
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0267 0.0044
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0748 1
Echinococcus multilocularis geminin 0.0188 0.3967 0.3949
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0267 0.0308
Loa Loa (eye worm) hypothetical protein 0.0153 0.3175 0.6338
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0267 0.1093
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0777 0.075
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0248 0.5
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0127 0.0098

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 193 nM Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells ChEMBL. 19326916
Ki (binding) > 1000 nM Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells ChEMBL. 19326916

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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