Detailed information for compound 988796

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 521.54 | Formula: C27H28FN5O5
  • H donors: 2 H acceptors: 4 LogP: 2.4 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=O)NC[C@@H]1OC(=O)N(C1)c1ccc(c(c1)F)N1CCN(CC1)C(=O)C(=O)c1c(C)[nH]c2c1cccc2
  • InChi: 1S/C27H28FN5O5/c1-16-24(20-5-3-4-6-22(20)30-16)25(35)26(36)32-11-9-31(10-12-32)23-8-7-18(13-21(23)28)33-15-19(38-27(33)37)14-29-17(2)34/h3-8,13,19,30H,9-12,14-15H2,1-2H3,(H,29,34)/t19-/m0/s1
  • InChiKey: GNVNJGOHKROCCN-IBGZPJMESA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0037 0.0221 0.0221
Schistosoma mansoni growth hormone secretagogue receptor 0.0033 0.0182 0.0248
Echinococcus multilocularis transfer RNA-Gly 0.0032 0.0168 0.0168
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0182 0.0182
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0355 0.1563
Loa Loa (eye worm) TWK-7 protein 0.0023 0.008 0.0123
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0114 0.1097
Plasmodium falciparum potassium channel 0.0023 0.008 0.1141
Echinococcus granulosus Nuclear hormone receptor HR96 0.0104 0.0896 0.0896
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Loa Loa (eye worm) serotonin transporter b 0.0091 0.0766 0.1187
Echinococcus granulosus 7TM GPCR rhodopsin 0.0033 0.0182 0.0182
Echinococcus multilocularis short transient receptor potential channel 6 0.0032 0.0169 0.0169
Onchocerca volvulus 0.0023 0.008 0.0142
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0221 0.2071 0.2819
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0177 0.1707
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.0918 0.4036
Echinococcus multilocularis glycogen phosphorylase 0.0557 0.5461 0.5461
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0032 0.0168 0.0229
Schistosoma mansoni opsin-like receptor 0.0033 0.0182 0.0248
Schistosoma mansoni nuclear receptor 0.0104 0.0896 0.1219
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0129 0.02
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.008 0.0108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0182 0.0248
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0015 0.0002 0.0002
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0033 0.0182 0.0283
Schistosoma mansoni transient receptor potential channel 0.0032 0.0168 0.0229
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0221 0.2071 0.3211
Schistosoma mansoni phd/f-box containing protein 0.0032 0.0174 0.0236
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0041 0.007
Echinococcus multilocularis ryanodine receptor 44f 0.0032 0.0168 0.0168
Echinococcus granulosus transient receptor potential cation channel 0.0032 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0183 0.0283
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0416 0.1579
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.012 0.1741
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0168 0.0229
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Loa Loa (eye worm) hypothetical protein 0.0221 0.2071 0.3211
Echinococcus granulosus g protein coupled receptor 0.0033 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0655 0.645 1
Echinococcus multilocularis allatostatin A receptor 0.0033 0.0182 0.0182
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0416 0.8126
Echinococcus granulosus voltage gated hydrogen channel 1 0.0032 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Brugia malayi hypothetical protein 0.0033 0.0182 0.0283
Loa Loa (eye worm) hypothetical protein 0.0022 0.0065 0.0101
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Brugia malayi hypoxia-induced factor 1 0.0162 0.1483 0.2298
Loa Loa (eye worm) hypothetical protein 0.0104 0.0896 0.1389
Schistosoma mansoni hypothetical protein 0.0033 0.0183 0.0249
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0117 0.1022 0.1391
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Brugia malayi Inositol-1 0.0037 0.0216 0.0335
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0002 0.0002
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0023 0.008 0.0123
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0182 0.0182
Schistosoma mansoni opsin-like receptor 0.0033 0.0182 0.0248
Echinococcus multilocularis neuropeptide s receptor 0.1007 1 1
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0623 0.0623
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Onchocerca volvulus 0.0091 0.0766 0.1399
Toxoplasma gondii exonuclease III APE 0.0057 0.0416 0.1791
Schistosoma mansoni cpg binding protein 0.0031 0.0158 0.0215
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Schistosoma mansoni calcium-activated potassium channel 0.0023 0.008 0.0108
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0032 0.0168 0.026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0033 0.0182 0.0182
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0009 0.0034
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0104 0.0896 0.1637
Brugia malayi Pre-SET motif family protein 0.0033 0.0177 0.0275
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0002 0.0002
Echinococcus multilocularis small conductance calcium activated potassium 0.0023 0.008 0.008
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0159 0.0159
Echinococcus granulosus ecdysone induced protein 78C 0.0221 0.2071 0.2071
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0032 0.0168 0.0168
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0221 0.2071 0.2071
Mycobacterium ulcerans endonuclease IV 0.0083 0.0679 0.2987
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0129 0.0221
Brugia malayi hypothetical protein 0.0018 0.0023 0.0036
Brugia malayi tailless protein 0.0104 0.0896 0.1389
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0037 0.0221 0.0301
Loa Loa (eye worm) hypothetical protein 0.0117 0.1022 0.1584
Brugia malayi jmjC domain containing protein 0.0032 0.0174 0.0269
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0009 0.0039
Echinococcus granulosus sodium leak channel non selective protein 0.0032 0.0168 0.0168
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0655 0.645 0.645
Echinococcus multilocularis transient receptor potential cation channel 0.0032 0.0168 0.0168
Brugia malayi Probable ClpP-like protease 0.0077 0.0623 0.0966
Loa Loa (eye worm) hypoxia-induced factor 1 0.0162 0.1483 0.2298
Onchocerca volvulus 0.0033 0.0182 0.033
Loa Loa (eye worm) hypothetical protein 0.0064 0.049 0.0759
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0799 0.7902 0.7902
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0304 0.0414
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Echinococcus granulosus G protein coupled receptor 139 0.0033 0.0182 0.0182
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0506 0.0689
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0355 0.1563
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0097 0.0823 0.112
Loa Loa (eye worm) hypothetical protein 0.0104 0.0896 0.1389
Schistosoma mansoni vesicular amine transporter 0.0032 0.0168 0.0229
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0095 0.0362
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Trypanosoma cruzi ion transport protein, putative 0.0023 0.008 0.0302
Echinococcus granulosus single minded 2 0.0042 0.0274 0.0274
Loa Loa (eye worm) DR-78 0.0104 0.0896 0.1389
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0182 0.0182
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0134 0.0208
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Echinococcus multilocularis somatostatin receptor 0.0033 0.0182 0.0182
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0216 0.0949
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0316 0.12
Schistosoma mansoni hypothetical protein 0.0359 0.3462 0.4713
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0032 0.0168 0.0168
Onchocerca volvulus 0.0033 0.0182 0.033
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0182 0.0182
Schistosoma mansoni hypothetical protein 0.0033 0.0182 0.0248
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0174 0.0659
Echinococcus multilocularis transient receptor potential cation channel 0.0032 0.0169 0.0169
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0069 0.0542 0.0841
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0009 0.0012
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0063 0.0479 0.0479
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0033 0.0182 0.0283
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0117 0.1022 0.1584
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.0918 0.4036
Echinococcus multilocularis sodium channel protein 0.0063 0.0479 0.0479
Brugia malayi nuclear receptor RXR 0.0117 0.1022 0.1584
Echinococcus granulosus GPCR family 2 0.0033 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0077 0.0623 0.0966
Loa Loa (eye worm) hypothetical protein 0.0221 0.2071 0.3211
Schistosoma mansoni jumonji domain containing protein 0.0032 0.0174 0.0236
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Toxoplasma gondii hypothetical protein 0.0214 0.2 0.8614
Plasmodium vivax glutathione reductase, putative 0.0047 0.0316 0.4633
Schistosoma mansoni glycogen phosphorylase 0.0241 0.2274 0.3095
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0009 0.0039
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0002 0.0003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0221 0.2071 0.2071
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0032 0.0168 0.0229
Loa Loa (eye worm) nuclear receptor NHR-67 0.0104 0.0896 0.1389
Schistosoma mansoni microtubule-associated protein tau 0.0744 0.7346 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0506 0.2226
Echinococcus granulosus serotonin transporter 0.0091 0.0766 0.0766
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0033 0.0182 0.0182
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0182 0.0182
Plasmodium vivax potassium channel, putative 0.0023 0.008 0.1141
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0033 0.0182 0.0182
Onchocerca volvulus 0.0033 0.0182 0.033
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Schistosoma mansoni neuropeptide receptor 0.0033 0.0182 0.0248
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0009 0.0175
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0182 0.0182
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.008 0.0108
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0183 0.0183
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0002 0.0003
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0066 0.0512 0.0696
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0122 0.1074 0.1074
Echinococcus granulosus intermediate filament protein 0.0029 0.0139 0.0139
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0009 0.0039
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.0918 0.4036
Schistosoma mansoni voltage-gated ion channel 0.0032 0.0168 0.0229
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Echinococcus granulosus potassium channel subfamily K 8 0.0023 0.008 0.008
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0216 0.0216
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0009 0.0098
Trypanosoma brucei calcium-activated potassium channel, putative 0.0023 0.008 0.0302
Brugia malayi Dopamine receptor 0.0033 0.0182 0.0283
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0069 0.0542 0.0841
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0004
Echinococcus granulosus serotonin receptor 0.0033 0.0182 0.0182
Schistosoma mansoni aryl hydrocarbon receptor 0.0052 0.0375 0.051
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0009 0.0034
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0032 0.0168 0.026
Loa Loa (eye worm) hypothetical protein 0.0104 0.0896 0.1389
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0416 0.0746
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0041 0.007
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0623 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0139 0.0216
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0258 0.0351
Echinococcus granulosus fmrfamide receptor 0.0033 0.0182 0.0182
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0182 0.0182
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0221 0.2071 0.2071
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0623 0.1137
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0216 0.039
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0416 0.0645
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0174 0.0659
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0679 1
Brugia malayi Serotonin receptor 0.0033 0.0182 0.0283
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0037 0.0221 0.0221
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0009 0.0039
Echinococcus multilocularis dnaJ subfamily B 0.0441 0.4292 0.4292
Brugia malayi carbohydrate phosphorylase 0.0557 0.5461 0.8466
Schistosoma mansoni RAR-like nuclear receptor 0.0221 0.2071 0.2819
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Echinococcus multilocularis twik family of potassium channels 0.0023 0.008 0.008
Schistosoma mansoni calcium-activated potassium channel 0.0023 0.008 0.0108
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.012 0.1741
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0032 0.0168 0.0229
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0416 0.0757
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0032 0.0168 0.026
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0065 0.0115
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0083 0.0679 0.2987
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0033 0.0182 0.0283
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0182 0.0248
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0304 0.0471
Echinococcus multilocularis orexin receptor type 2 0.0033 0.0182 0.0182
Onchocerca volvulus Protein ultraspiracle homolog 0.0221 0.2071 0.379
Brugia malayi Thioredoxin reductase 0.0047 0.0316 0.049
Schistosoma mansoni hypothetical protein 0.0033 0.0183 0.0249
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0182 0.0248
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0384 0.0522
Echinococcus granulosus tachykinin peptides receptor 99D 0.0033 0.0182 0.0182
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0023 0.008 0.0123
Echinococcus multilocularis serotonin receptor 0.0033 0.0182 0.0182
Echinococcus granulosus g protein coupled receptor 0.0033 0.0182 0.0182
Entamoeba histolytica glycogenphosphorylase, putative 0.0241 0.2274 0.4077
Echinococcus multilocularis phd:f box containing protein 0.0032 0.0174 0.0174
Schistosoma mansoni voltage-gated cation channel 0.0655 0.645 0.878
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Echinococcus multilocularis serotonin transporter 0.0091 0.0766 0.0766
Echinococcus granulosus potassium voltage gated channel protein 0.0032 0.0168 0.0168
Onchocerca volvulus 0.0033 0.0182 0.033
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Schistosoma mansoni lamin 0.0029 0.0139 0.019
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0655 0.645 0.645
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0506 0.0689
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0002 0.0003
Schistosoma mansoni nuclear receptor 0.0104 0.0896 0.1219
Echinococcus multilocularis hyperpolarization activated cyclic 0.0037 0.0221 0.0221
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0512 0.225
Echinococcus multilocularis serotonin receptor 0.0033 0.0182 0.0182
Echinococcus granulosus Nuclear hormone receptor HR96 0.0104 0.0896 0.0896
Onchocerca volvulus 0.0023 0.008 0.0142
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0117 0.1022 0.1391
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0506 0.218
Onchocerca volvulus 0.0033 0.0182 0.033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0182 0.0248
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Brugia malayi M-phase phosphoprotein, mpp8 0.0109 0.0947 0.1468
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0009 0.0012
Onchocerca volvulus 0.0023 0.008 0.0142
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0183 0.0183
Onchocerca volvulus Neuropeptide F receptor homolog 0.0033 0.0182 0.033
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0237 0.0237
Brugia malayi nuclear receptor NHR-67 0.0104 0.0896 0.1389
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0032 0.0168 0.0723
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0104 0.0896 0.0896
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0041 0.007
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0221 0.2071 0.2071
Plasmodium falciparum flap endonuclease 1 0.0028 0.0129 0.1875
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0032 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0033 0.0182 0.0248
Echinococcus granulosus calcium activated potassium channel variant 0.0023 0.008 0.008
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0168 0.0229
Onchocerca volvulus 0.0104 0.0896 0.1637
Echinococcus granulosus tumor protein p63 0.0364 0.3519 0.3519
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0032 0.0168 0.026
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0679 1
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0023 0.008 0.0302
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0095 0.0362
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0623 0.8113
Echinococcus granulosus voltage gated potassium channel 0.0041 0.0258 0.0258
Brugia malayi hypothetical protein 0.0033 0.0182 0.0283
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0032 0.0168 0.0168
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0416 0.0416
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0216 0.082
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0023 0.008 0.0123
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0216 0.093
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0023 0.008 0.0123
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0449 0.1936
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0416 0.1579
Schistosoma mansoni hypothetical protein 0.0033 0.0182 0.0248
Echinococcus granulosus allatostatin A receptor 0.0033 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Giardia lamblia Glycogen phosphorylase 0.0557 0.5461 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0009 0.0098
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0032 0.0174 0.0748
Onchocerca volvulus 0.0033 0.0182 0.033
Echinococcus granulosus twik family of potassium channels 0.0023 0.008 0.008
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0177 0.0764
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0281 0.2682 0.4158
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0032 0.0168 0.0229
Brugia malayi hypothetical protein 0.0033 0.0182 0.0283
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0241 0.2274 1
Mycobacterium ulcerans hypothetical protein 0.0022 0.0065 0.0287
Echinococcus multilocularis glycogen phosphorylase 0.0557 0.5461 0.5461
Toxoplasma gondii ion channel protein 0.0023 0.008 0.0343
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0221 0.2071 0.3211
Brugia malayi Serotonin receptor 0.0033 0.0182 0.0283
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0174 0.0269
Schistosoma mansoni neuropeptide f receptor 76f 0.0033 0.0182 0.0248
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0004
Schistosoma mansoni 60S ribosomal protein L21 0.0036 0.0205 0.0279
Brugia malayi hypothetical protein 0.0023 0.008 0.0123
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0182 0.0182
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0415 0.0643
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0032 0.0168 0.0229
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0129 0.0231
Brugia malayi hypothetical protein 0.0117 0.1022 0.1584
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0182 0.0182
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0221 0.2071 0.3211
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0139 0.0216
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0182 0.0182
Leishmania major cytochrome p450-like protein 0.0025 0.0095 0.1861
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0004
Echinococcus granulosus death domain containing protein 0.0016 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Toxoplasma gondii hypothetical protein 0.0027 0.0114 0.049
Schistosoma mansoni cpg binding protein 0.0033 0.0176 0.024
Echinococcus multilocularis Glycosyl transferase, family 35 0.0557 0.5461 0.5461
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0009 0.0039
Onchocerca volvulus 0.0033 0.0182 0.033
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Brugia malayi Cytochrome P450 family protein 0.0056 0.0415 0.0643
Loa Loa (eye worm) hypothetical protein 0.0104 0.0896 0.1389
Brugia malayi nuclear receptor NHR-88 0.0221 0.2071 0.3211
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0216 0.4218
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0623 0.0848
Echinococcus granulosus 7tm_1 domain containing protein 0.0033 0.0182 0.0182
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0221 0.2071 0.3211
Loa Loa (eye worm) uncoordinated protein 58 0.0023 0.008 0.0123
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0037 0.0221 0.0301
Schistosoma mansoni neuropeptide receptor 0.0033 0.0182 0.0248
Schistosoma mansoni biogenic amine receptor 0.0033 0.0182 0.0248
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0301 0.041
Loa Loa (eye worm) ion channel NompC 0.0032 0.0168 0.026
Echinococcus multilocularis jumonji domain containing 1A 0.0032 0.0174 0.0174
Loa Loa (eye worm) TWK-28 protein 0.0023 0.008 0.0123
Brugia malayi ORL1-like opioid receptor 0.0033 0.0182 0.0283
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0023 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0176 0.162 0.2511
Brugia malayi Calcitonin receptor-like protein seb-1 0.0106 0.091 0.1411
Echinococcus multilocularis twik family of potassium channels 0.0023 0.008 0.008
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0032 0.0168 0.0229
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0065 0.0101
Schistosoma mansoni ryanodine receptor related 0.0032 0.0168 0.0229
Loa Loa (eye worm) inositol-1 0.0037 0.0216 0.0335
Echinococcus multilocularis transient receptor potential cation channel 0.0032 0.0169 0.0169
Echinococcus multilocularis ecdysone induced protein 78C 0.0221 0.2071 0.2071
Onchocerca volvulus 0.0033 0.0182 0.033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0041 0.007
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0647 0.0647
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0023 0.008 0.0123
Echinococcus granulosus sex peptide receptor 0.0033 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0083 0.0679 0.1053
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0009 0.0034
Brugia malayi jmjC domain containing protein 0.0032 0.0174 0.0269
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.1037 0.4562
Brugia malayi G-protein coupled receptor 0.0033 0.0182 0.0283
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0002 0.0002
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0009 0.0039
Echinococcus granulosus dro:myosuppressin receptor 0.0033 0.0182 0.0182
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0009 0.0034
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0002 0.0002
Treponema pallidum sodium- and chloride- dependent transporter 0.0091 0.0766 1
Schistosoma mansoni inositol monophosphatase 0.0037 0.0216 0.0294
Brugia malayi GnHR receptor homolog 0.0033 0.0182 0.0283
Schistosoma mansoni coup transcription factor 0.0221 0.2071 0.2819
Echinococcus multilocularis potassium channel subfamily K 8 0.0023 0.008 0.008
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0023 0.008 0.008
Brugia malayi jmjC domain containing protein 0.0032 0.0174 0.0269
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0182 0.0248
Echinococcus granulosus transient receptor potential cation channel 0.0032 0.0168 0.0168
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0655 0.645 0.645
Brugia malayi ion channel NompC 0.0032 0.0168 0.026
Toxoplasma gondii thioredoxin reductase 0.0047 0.0316 0.1361
Loa Loa (eye worm) hypothetical protein 0.0221 0.2071 0.3211
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0023 0.008 0.0123
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0104 0.0896 0.0896
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0041 0.007
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0032 0.0168 0.026
Loa Loa (eye worm) hypothetical protein 0.0033 0.0183 0.0283
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0037 0.0221 0.0342
Echinococcus multilocularis GPCR, family 2 0.0033 0.0183 0.0183
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0304 0.0304
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0033 0.0182 0.0182
Echinococcus granulosus transient receptor potential gamma protein 0.0032 0.0168 0.0168
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0221 0.2071 0.3211
Toxoplasma gondii hypothetical protein 0.0015 0.0002 0.001
Echinococcus granulosus transient receptor potential cation channel 0.0032 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Schistosoma mansoni hypothetical protein 0.0359 0.3462 0.4713
Schistosoma mansoni calcium-activated potassium channel 0.0032 0.0168 0.0229
Brugia malayi Steroid receptor seven-up type 2 0.0221 0.2071 0.3211
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0655 0.645 0.878
Brugia malayi hypothetical protein 0.0104 0.0896 0.1389
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Schistosoma mansoni nuclear hormone receptor 0.0104 0.0896 0.1219
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0221 0.2071 0.2819
Onchocerca volvulus 0.0029 0.0139 0.0251
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0506 0.2226
Echinococcus granulosus neuropeptide receptor 0.0033 0.0182 0.0182
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0276 0.2633 1
Leishmania major protein kinase, putative 0.0019 0.0036 0.0713
Echinococcus multilocularis shaker cognate 0.0032 0.0168 0.0168
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0034 0.0191 0.0191
Schistosoma mansoni netrin receptor unc5 0.0016 0.0002 0.0003
Onchocerca volvulus 0.0033 0.0182 0.033
Onchocerca volvulus Bile acid receptor homolog 0.0221 0.2071 0.379
Brugia malayi CXXC zinc finger family protein 0.0031 0.0158 0.0245
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0655 0.645 0.645
Loa Loa (eye worm) hypothetical protein 0.0104 0.0896 0.1389
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0032 0.0168 0.026
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0221 0.2071 0.3211
Echinococcus multilocularis neuropeptide FF receptor 2 0.0033 0.0182 0.0182
Schistosoma mansoni biogenic amine receptor 0.0033 0.0182 0.0248
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0069 0.0542 0.0542
Schistosoma mansoni retinoic acid receptor RXR 0.0221 0.2071 0.2819
Mycobacterium ulcerans ion transport protein 0.0023 0.008 0.035
Echinococcus granulosus TRP transient receptor potential channel 0.0032 0.0168 0.0168
Echinococcus granulosus transient receptor potential cation channel 0.0032 0.0168 0.0168
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0032 0.0168 0.0168
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0655 0.645 1
Brugia malayi hypothetical protein 0.0033 0.0182 0.0283
Schistosoma mansoni cpg binding protein 0.0033 0.0176 0.024
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0316 0.139
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0104 0.0896 0.1389
Onchocerca volvulus 0.0033 0.0182 0.033
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Toxoplasma gondii transporter, cation channel family protein 0.0246 0.2322 1
Brugia malayi MH2 domain containing protein 0.0124 0.1096 0.17
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0033 0.0182 0.0248
Onchocerca volvulus 0.0033 0.0182 0.033
Schistosoma mansoni hypothetical protein 0.0033 0.0183 0.0249
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0114 0.1648
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0221 0.0301
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0009 0.0034
Echinococcus multilocularis dro:myosuppressin receptor 0.0033 0.0182 0.0182
Onchocerca volvulus 0.0023 0.008 0.0142
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0623 0.274
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0032 0.0168 0.0168
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0032 0.0168 0.0168
Trichomonas vaginalis set domain proteins, putative 0.0256 0.2427 0.4442
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0182 0.0182
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0095 0.0148
Loa Loa (eye worm) steroid hormone receptor 0.0221 0.2071 0.3211
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0104 0.0896 0.1219
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0106 0.091 0.1411
Schistosoma mansoni ap endonuclease 0.0057 0.0416 0.0566
Brugia malayi glutathione reductase 0.0047 0.0316 0.049
Brugia malayi hypothetical protein 0.0033 0.0182 0.0283
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0023 0.008 0.0123
Toxoplasma gondii hypothetical protein 0.0015 0.0002 0.001
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0355 0.0355
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0023 0.008 0.0123
Brugia malayi ecdysone receptor 0.0104 0.0896 0.1389
Echinococcus granulosus short transient receptor potential channel 6 0.0032 0.0168 0.0168
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0221 0.2071 0.2071
Brugia malayi hypothetical protein 0.0015 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.012 0.0186
Schistosoma mansoni two-pore calcium channel 0.0032 0.0168 0.0229
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0023 0.008 0.008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0304 0.0304
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Echinococcus multilocularis G protein coupled receptor 139 0.0033 0.0182 0.0182
Brugia malayi conserved hypotetical protein 0.0104 0.0896 0.1389
Echinococcus multilocularis voltage gated potassium channel 0.0032 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0221 0.2071 0.3211
Entamoeba histolytica glycogen phosphorylase, putative 0.0557 0.5461 1
Brugia malayi hypothetical protein 0.0023 0.008 0.0123
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0304 0.0414
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0032 0.0168 0.0303
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Echinococcus multilocularis JmjC domain containing protein 4 0.0032 0.0174 0.0174
Echinococcus multilocularis lysine specific demethylase 6a 0.0032 0.0174 0.0174
Loa Loa (eye worm) melatonin receptor type 1A 0.0033 0.0182 0.0283
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0032 0.0168 0.0168
Brugia malayi Nuclear hormone receptor-like 1 0.0221 0.2071 0.3211
Toxoplasma gondii transporter, cation channel family protein 0.0032 0.0168 0.0723
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0009 0.0034
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0037 0.0221 0.0301
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Brugia malayi Nuclear hormone receptor-like 1 0.0117 0.1022 0.1584
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0066 0.0512 1
Brugia malayi hypothetical protein 0.0032 0.0168 0.026
Loa Loa (eye worm) hypothetical protein 0.0109 0.0947 0.1468
Loa Loa (eye worm) hypothetical protein 0.0246 0.2322 0.3599
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0033 0.0182 0.0283
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0221 0.2071 0.3211
Echinococcus granulosus JmjC domain containing protein 4 0.0032 0.0174 0.0174
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0506 0.9892
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0512 0.0512
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0182 0.0283
Onchocerca volvulus 0.0039 0.0237 0.0431
Plasmodium falciparum glutathione reductase 0.0016 0.0009 0.0098
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0033 0.0182 0.0182
Echinococcus granulosus two pore calcium channel protein 1 0.0032 0.0168 0.0168
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0033 0.0182 0.0182
Echinococcus multilocularis potassium channel subfamily K 0.0023 0.008 0.008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0867 0.8582 0.8582
Schistosoma mansoni neuropeptide receptor 0.0033 0.0182 0.0248
Echinococcus granulosus g-protein coupled receptor 0.0033 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0033 0.0177 0.0275
Loa Loa (eye worm) glycogen phosphorylase 0.0557 0.5461 0.8466
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0083 0.0679 0.1053
Loa Loa (eye worm) hypothetical protein 0.0221 0.2071 0.3211
Loa Loa (eye worm) hypothetical protein 0.0109 0.0948 0.147
Echinococcus multilocularis voltage dependent calcium channel 0.0655 0.645 0.645
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0037 0.0221 0.0342
Loa Loa (eye worm) hypothetical protein 0.0032 0.0174 0.0269
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0023 0.008 0.035
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0009 0.0175
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0009 0.0011
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0002 0.001
Brugia malayi nuclear hormone receptor 0.0104 0.0896 0.1389
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0182 0.0182
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.008 0.0108
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Echinococcus multilocularis transient receptor potential gamma protein 0.0032 0.0168 0.0168
Brugia malayi jmjC domain containing protein 0.0124 0.1092 0.1693
Schistosoma mansoni hypothetical protein 0.0016 0.0002 0.0003
Leishmania major potassium channel subunit-like protein 0.0023 0.008 0.1555
Brugia malayi Protein kinase domain containing protein 0.0016 0.0002 0.0004
Echinococcus multilocularis voltage dependent calcium channel 0.0655 0.645 0.645
Onchocerca volvulus 0.0023 0.008 0.0142
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0023 0.008 0.0123
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.008 0.0302
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0183 0.0183
Echinococcus granulosus geminin 0.0359 0.3462 0.3462
Schistosoma mansoni single-minded 0.0052 0.0375 0.051
Schistosoma mansoni jumonji/arid domain-containing protein 0.0124 0.1092 0.1486
Schistosoma mansoni sodium/chloride dependent transporter 0.0091 0.0766 0.1043
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0416 0.0416
Echinococcus granulosus hyperpolarization activated cyclic 0.0037 0.0221 0.0221
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0216 0.3369
Brugia malayi Dopamine receptor protein 2 0.0033 0.0182 0.0283
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0037 0.0221 0.0301
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0177 0.0241
Onchocerca volvulus 0.0033 0.0182 0.033
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0002 0.0003
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0416 0.5374
Schistosoma mansoni voltage-dependent calcium channel 0.0032 0.0168 0.0229
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0221 0.2071 0.3211
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0032 0.0168 0.0638
Schistosoma mansoni lamin 0.0029 0.0139 0.019
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.012 0.0456
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0004 0.0005
Plasmodium falciparum potassium channel 0.0023 0.008 0.1141
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0623 0.9171
Mycobacterium ulcerans epimerase 0.0022 0.0065 0.0287
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0183 0.0283
Leishmania major hypothetical protein, unknown function 0.0032 0.0168 0.3282
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.0918 0.4036
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0033 0.0182 0.0283
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0032 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Schistosoma mansoni calcium-activated potassium channel 0.0023 0.008 0.0108
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Schistosoma mansoni hypothetical protein 0.0072 0.0573 0.0781
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0023 0.008 0.0123
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0168 0.0229
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0182 0.0283
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.0573 0.0889
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0032 0.0168 0.0168
Schistosoma mansoni amine GPCR 0.0033 0.0182 0.0248
Chlamydia trachomatis endonuclease IV 0.0083 0.0679 0.124
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0033 0.0182 0.0283
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Echinococcus granulosus tm gpcr rhodopsin 0.0867 0.8582 0.8582
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0032 0.0174 0.0659
Loa Loa (eye worm) hypothetical protein 0.0053 0.0384 0.0595
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0032 0.0168 0.0638
Echinococcus multilocularis Ankyrin 0.0016 0.0004 0.0004
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.008 0.0108
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0002 0.001
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0002 0.0002
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0506 0.2226
Schistosoma mansoni alpha-1 adrenergic receptor 0.0033 0.0182 0.0248
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0002 0.0003
Onchocerca volvulus 0.0033 0.0182 0.033
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Echinococcus granulosus potassium voltage gated channel protein 0.0032 0.0168 0.0168
Loa Loa (eye worm) glutathione reductase 0.0047 0.0316 0.049
Brugia malayi Uncoordinated protein 44 0.0016 0.0002 0.0004
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0183 0.0283
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0655 0.645 0.645
Entamoeba histolytica glycogen phosphorylase, putative 0.0557 0.5461 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0221 0.2071 0.2071
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0114 0.1386
Echinococcus granulosus ryanodine receptor 44f 0.0032 0.0168 0.0168
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0114 0.1648
Loa Loa (eye worm) hypothetical protein 0.0091 0.0766 0.1187
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0033 0.0182 0.0182
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0104 0.0896 0.1219
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0237 0.1044
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0182 0.0182
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0221 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0221 0.2071 0.3211
Brugia malayi Flap endonuclease-1 0.0028 0.0129 0.02
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0104 0.0896 0.0896
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0221 0.2071 0.2819
Echinococcus multilocularis lysine specific demethylase 5A 0.0122 0.1074 0.1074
Entamoeba histolytica glycogen phosphorylase, putative 0.0241 0.2274 0.4077
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0221 0.2071 0.3211
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0221 0.2071 0.2819
Echinococcus granulosus dnaJ subfamily B 0.0441 0.4292 0.4292
Echinococcus granulosus two pore calcium channel protein 2 0.0032 0.0168 0.0168
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0091 0.0766 0.1043
Echinococcus multilocularis G-protein coupled receptor, putative 0.0033 0.0182 0.0182
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0023 0.008 0.0123
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0002 0.0002
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0032 0.0168 0.026
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0416 0.1829
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0182 0.0248
Loa Loa (eye worm) hypothetical protein 0.0091 0.0766 0.1187
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0083 0.0679 0.6547
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0129 0.0491
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0416 0.0625
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0623 0.274
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0241 0.2274 1
Echinococcus multilocularis potassium large conductance calcium activated 0.0032 0.0168 0.0168
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0168 0.0229
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0304 0.0304
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0009 0.0009
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0182 0.0248
Schistosoma mansoni phosphatidylserine receptor 0.0032 0.0174 0.0236
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0032 0.0168 0.0303
Onchocerca volvulus 0.0032 0.0168 0.0303
Echinococcus granulosus nuclear receptor nhr 48 0.0104 0.0896 0.0896
Schistosoma mansoni glycogen phosphorylase 0.0557 0.5461 0.7433
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0002 0.0003
Mycobacterium ulcerans transmembrane cation transporter 0.0023 0.008 0.035
Echinococcus granulosus neuropeptide receptor 0.0033 0.0182 0.0182
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0182 0.0182
Schistosoma mansoni amine GPCR 0.0033 0.0182 0.0248
Loa Loa (eye worm) hypothetical protein 0.0214 0.2 0.31
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0065 0.0629
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0009 0.0034
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0182 0.0182
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0221 0.2071 0.379
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0097 0.0823 0.0823
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0041 0.0258 0.04
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0104 0.0896 0.0896
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0032 0.0169 0.0262
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0032 0.0168 0.0168
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0041 0.007
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0032 0.0168 0.0168
Schistosoma mansoni zinc finger protein 0.0104 0.0896 0.1219
Echinococcus granulosus neuropeptide receptor A26 0.1007 1 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0416 0.6108
Echinococcus granulosus cpg binding protein 0.0033 0.0176 0.0176
Onchocerca volvulus 0.0033 0.0182 0.033
Trichomonas vaginalis glycogen phosphorylase, putative 0.0557 0.5461 1
Schistosoma mansoni hypothetical protein 0.0033 0.0183 0.0249
Loa Loa (eye worm) nuclear hormone receptor 0.0104 0.0896 0.1389
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0032 0.0168 0.0229
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0015 0.0002 0.0002
Brugia malayi putative neuropeptide receptor 0.0033 0.0182 0.0283
Loa Loa (eye worm) ryanodine receptor 0.0032 0.0168 0.026
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0033 0.0182 0.0283
Echinococcus granulosus lamin 0.0029 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0221 0.2071 0.3211
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0623 0.2684
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0065 0.0287
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0182 0.0248
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0008 0.0009
Echinococcus granulosus lysine specific demethylase 5A 0.0124 0.1092 0.1092
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0002 0.0004
Leishmania major hypothetical protein, conserved 0.0023 0.008 0.1555
Loa Loa (eye worm) hypothetical protein 0.0104 0.0896 0.1389
Echinococcus granulosus potassium voltage gated channel protein 0.0032 0.0168 0.0168
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0117 0.1022 0.1584
Leishmania major trypanothione reductase 0.0047 0.0316 0.6175
Loa Loa (eye worm) hypothetical protein 0.0032 0.0174 0.0269
Plasmodium vivax potassium channel, putative 0.0023 0.008 0.1141
Plasmodium falciparum glutathione reductase 0.0047 0.0316 0.4633
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0623 0.1137
Schistosoma mansoni neuropeptide receptor 0.0033 0.0182 0.0248
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0097 0.0823 0.0823
Echinococcus multilocularis potassium voltage gated channel protein 0.0032 0.0168 0.0168
Brugia malayi hypothetical protein 0.0117 0.1022 0.1584
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0033 0.0182 0.0248
Echinococcus multilocularis potassium voltage gated channel protein 0.0032 0.0168 0.0168
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0037 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Echinococcus granulosus glycogen phosphorylase 0.0557 0.5461 0.5461
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0182 0.0248
Entamoeba histolytica hypothetical protein 0.0039 0.0237 0.0293
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Schistosoma mansoni opsin-like receptor 0.0033 0.0182 0.0248
Echinococcus granulosus hyperpolarization activated cyclic 0.0037 0.0221 0.0221
Echinococcus granulosus hypothetical protein 0.0033 0.0182 0.0182
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0623 0.9171
Schistosoma mansoni hypothetical protein 0.0056 0.0408 0.0556
Brugia malayi nuclear hormone receptor 0.0221 0.2071 0.3211
Brugia malayi AKH receptor 0.0033 0.0182 0.0283
Entamoeba histolytica glycogen phosphorylase, putative 0.0241 0.2274 0.4077
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0009 0.0034
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0041 0.007
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0023 0.008 0.0123
Echinococcus multilocularis g-protein coupled receptor 0.0033 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Echinococcus granulosus microtubule associated protein 2 0.0744 0.7346 0.7346
Brugia malayi hypothetical protein 0.0039 0.0237 0.0368
Echinococcus granulosus g protein coupled receptor 0.0033 0.0182 0.0182
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0122 0.1074 0.1074
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0129 0.0556
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0416 0.6624
Loa Loa (eye worm) hypothetical protein 0.0104 0.0896 0.1389
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0003 0.0005
Echinococcus granulosus thyroid hormone receptor alpha 0.0104 0.0896 0.0896
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.006 0.0454 0.0827
Schistosoma mansoni protein phosphatase 2C 0.0032 0.0174 0.0236
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Brugia malayi olfactory channel protein osm-9 0.0032 0.0169 0.0262
Echinococcus multilocularis potassium voltage gated channel protein 0.0032 0.0168 0.0168
Brugia malayi hypothetical protein 0.0033 0.0182 0.0283
Schistosoma mansoni biogenic amine receptor 0.0033 0.0182 0.0248
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0117 0.1022 0.1022
Loa Loa (eye worm) hypothetical protein 0.0104 0.0896 0.1389
Echinococcus granulosus potassium large conductance calcium activated 0.0032 0.0168 0.0168
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0183 0.0183
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0416 0.0757
Loa Loa (eye worm) voltage-gated calcium channel 0.0032 0.0168 0.026
Loa Loa (eye worm) calcium channel 0.0655 0.645 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0033 0.0182 0.0248
Schistosoma mansoni amine GPCR 0.0033 0.0182 0.0248
Echinococcus granulosus somatostatin receptor 0.0033 0.0182 0.0182
Brugia malayi Cytochrome P450 family protein 0.0025 0.0095 0.0148
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.0918 0.8847
Echinococcus granulosus peptide allatostatin:somatostatin 0.0033 0.0182 0.0182
Brugia malayi jmjC domain containing protein 0.0032 0.0174 0.0269
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0009 0.0098
Schistosoma mansoni histamine h1 receptor 0.0033 0.0182 0.0248
Schistosoma mansoni thyroid hormone receptor 0.0221 0.2071 0.2819
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0355 0.0355
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0032 0.0168 0.026
Brugia malayi neuropeptide F receptor 0.0033 0.0182 0.0283
Brugia malayi Cyclic-nucleotide gated cation channel 0.0037 0.0221 0.0342
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0174 0.0269
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0216 0.0253
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0416 0.6108
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0066 0.0512 0.225
Brugia malayi Tachykinin-like peptides receptor 99D 0.0033 0.0182 0.0283
Brugia malayi RE15519p 0.0033 0.0182 0.0283
Loa Loa (eye worm) voltage-gated potassium channel 0.0032 0.0168 0.026
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0182 0.0182
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.006 0.0454 0.0827
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0182 0.0182
Brugia malayi hypothetical protein 0.0033 0.0182 0.0283
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Brugia malayi Dopamine receptor protein 1 0.0033 0.0182 0.0283
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0182 0.0182
Echinococcus granulosus orexin receptor type 2 0.0033 0.0182 0.0182
Brugia malayi hypothetical protein 0.0027 0.012 0.0186
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.1037 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0221 0.2071 0.2819
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0506 0.0506
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0182 0.0248
Brugia malayi hypothetical protein 0.0033 0.0182 0.0283
Schistosoma mansoni amine GPCR 0.0367 0.3542 0.4822
Brugia malayi Transient-receptor-potential like protein 0.0032 0.0168 0.026
Onchocerca volvulus 0.0109 0.0947 0.1731
Brugia malayi hypothetical protein 0.0033 0.0182 0.0283
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0032 0.0168 0.026
Loa Loa (eye worm) jmjC domain-containing protein 0.0124 0.1092 0.1693
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0221 0.2071 0.3211
Loa Loa (eye worm) TYRA-2 protein 0.0033 0.0182 0.0283
Schistosoma mansoni transient receptor potential channel 0.0032 0.0169 0.023
Echinococcus granulosus shaker cognate 0.0032 0.0168 0.0168
Echinococcus multilocularis neuropeptide receptor A26 0.1007 1 1
Onchocerca volvulus 0.0033 0.0182 0.033
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0216 0.082
Echinococcus granulosus potassium voltage gated channel protein 0.0032 0.0168 0.0168
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0168 0.0229
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0032 0.0168 0.026
Echinococcus granulosus Ankyrin 0.0016 0.0004 0.0004
Trypanosoma cruzi ion transport protein, putative 0.0023 0.008 0.0302
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0002 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0073 0.0579 0.0789
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0009 0.0098
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0221 0.2071 0.2071
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0304 0.0304
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0168 0.0229
Leishmania major hypothetical protein, conserved 0.0023 0.008 0.1555
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0168 0.0229
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.008 0.0302
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0216 0.039
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Loa Loa (eye worm) hypothetical protein 0.0104 0.0896 0.1389
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Mycobacterium tuberculosis Probable reductase 0.0106 0.0918 0.4036
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.008 0.0108
Loa Loa (eye worm) hypothetical protein 0.0214 0.2 0.31
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0002 0.0004
Entamoeba histolytica hypothetical protein 0.0039 0.0237 0.0293
Brugia malayi intermediate filament protein 0.0029 0.0139 0.0216
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0416 0.1579
Brugia malayi PAS domain containing protein 0.0052 0.0375 0.0581
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0032 0.0168 0.0168
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0168 0.0229
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0037 0.0221 0.0221
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0221 0.2071 0.3211
Echinococcus multilocularis nuclear receptor nhr 48 0.0104 0.0896 0.0896
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0221 0.2071 0.3211
Onchocerca volvulus Glycogen phosphorylase homolog 0.0557 0.5461 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0221 0.2071 0.2071
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0032 0.0174 0.0236
Schistosoma mansoni transient receptor potential channel 4 0.0032 0.0168 0.0229
Schistosoma mansoni ap endonuclease 0.0057 0.0416 0.0566
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0041 0.007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0004
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0002 0.0003
Echinococcus granulosus potassium voltage gated channel protein 0.0032 0.0168 0.0168
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0033 0.0182 0.0283
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0033 0.0182 0.033
Onchocerca volvulus 0.0221 0.2071 0.379
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0221 0.2071 0.2071
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0037 0.0221 0.0221
Schistosoma mansoni jumonji/arid domain-containing protein 0.0124 0.1092 0.1486
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.1037 0.4562
Echinococcus granulosus transient receptor potential cation channel 0.0032 0.0168 0.0168
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.012 0.0517
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0033 0.0182 0.0248
Brugia malayi larval opioid receptor 0.0033 0.0182 0.0283
Trypanosoma brucei trypanothione reductase 0.0047 0.0316 0.12
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0237 0.0368
Onchocerca volvulus 0.0029 0.0139 0.0251
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0037 0.0221 0.0301
Loa Loa (eye worm) hypothetical protein 0.0106 0.091 0.1411
Loa Loa (eye worm) norepinephrine transporter 0.0091 0.0766 0.1187
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0091 0.0766 0.1187
Loa Loa (eye worm) hypothetical protein 0.0091 0.0766 0.1187
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.052 0.0708
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0182 0.0283
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0355 0.3426
Echinococcus multilocularis hyperpolarization activated cyclic 0.0037 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0028 0.0132 0.0238
Toxoplasma gondii ion channel protein 0.0023 0.008 0.0343
Echinococcus granulosus hypothetical protein 0.0032 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0129 0.0092
Toxoplasma gondii hypothetical protein 0.0032 0.0168 0.0723
Echinococcus multilocularis sex peptide receptor 0.0033 0.0182 0.0182
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0015 0.0002 0.0004
Echinococcus multilocularis transient receptor potential cation channel 0.0032 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0182 0.0248
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.1096 0.17
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0009 0.0034
Schistosoma mansoni transient receptor potential channel 0.0032 0.0168 0.0229
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0182 0.0248
Plasmodium vivax SET domain protein, putative 0.0033 0.0177 0.2587
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0216 0.0216
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0023 0.008 0.0123
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0033 0.0182 0.0182
Echinococcus multilocularis short transient receptor potential channel 6 0.0032 0.0168 0.0168
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0023 0.008 0.0123
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0023 0.008 0.0123
Echinococcus multilocularis lamin dm0 0.0029 0.0139 0.0139
Echinococcus multilocularis calcium activated potassium channel 0.0032 0.0168 0.0168
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0009 0.0014
Brugia malayi nuclear hormone receptor family member odr-7 0.0104 0.0896 0.1389
Onchocerca volvulus 0.0045 0.0301 0.0548
Brugia malayi Death domain containing protein 0.0016 0.0002 0.0004
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0065 0.0287
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0182 0.0182
Brugia malayi hypothetical protein 0.0109 0.0948 0.147
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0623 0.6007
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0009 0.0034
Brugia malayi Cytochrome P450 family protein 0.0025 0.0095 0.0148
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0416 0.1829
Brugia malayi neuropeptide F receptor 0.0033 0.0182 0.0283
Onchocerca volvulus 0.0023 0.008 0.0142
Echinococcus multilocularis musashi 0.0029 0.0139 0.0139
Brugia malayi orphan nuclear receptor NR2E1 0.0104 0.0896 0.1389
Toxoplasma gondii endonuclease IV APN 0.0083 0.0679 0.2926
Schistosoma mansoni hypothetical protein 0.0023 0.008 0.0108
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0023 0.008 0.0123
Schistosoma mansoni flap endonuclease-1 0.0025 0.0102 0.0139
Echinococcus multilocularis cpg binding protein 0.0033 0.0176 0.0176
Echinococcus multilocularis lamin 0.0029 0.0139 0.0139
Echinococcus granulosus neuropeptide FF receptor 2 0.0033 0.0182 0.0182
Brugia malayi follicle stimulating hormone receptor 0.0281 0.2682 0.4158
Brugia malayi nuclear receptor NHR-88 0.0104 0.0896 0.1389
Echinococcus granulosus potassium channel subfamily K 0.0023 0.008 0.008
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0129 0.0129
Schistosoma mansoni nuclear hormone receptor 0.0221 0.2071 0.2819
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0023 0.008 0.0302
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0205 0.0279
Echinococcus granulosus potassium channel subfamily K 8 0.0023 0.008 0.008
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0117 0.1022 0.1022
Echinococcus granulosus glycogen phosphorylase 0.0557 0.5461 0.5461
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0129 0.2525
Echinococcus granulosus transient receptor potential cation channel 0.0032 0.0169 0.0169
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0069 0.0542 0.0542
Schistosoma mansoni intermediate filament proteins 0.0029 0.0139 0.019
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0095 0.0148
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.008 0.0108
Schistosoma mansoni myosin xvIII 0.0033 0.0182 0.0248
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Schistosoma mansoni sodium-dependent amino acid transporter 0.0015 0.0002 0.0003
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0104 0.0896 0.0896
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0221 0.2071 0.2819
Loa Loa (eye worm) hypothetical protein 0.0104 0.0896 0.1389
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0168 0.0229
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0028 0.0132 0.0238
Onchocerca volvulus 0.0053 0.0384 0.0699
Brugia malayi cation channel family protein 0.0032 0.0168 0.026
Schistosoma mansoni nuclear hormone receptor 0.0104 0.0896 0.1219
Echinococcus multilocularis potassium channel subfamily K 8 0.0023 0.008 0.008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0221 0.2071 0.3211
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0276 0.2633 1
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0066 0.0512 0.0793
Brugia malayi nuclear receptor RXR 0.0104 0.0896 0.1389
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0009 0.0034
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0237 0.0237
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0174 0.0269
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0015 0.0002 0.0002
Echinococcus multilocularis transient receptor potential cation channel 0.0032 0.0168 0.0168
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0023 0.008 0.0123
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0033 0.0182 0.0182
Schistosoma mansoni hypothetical protein 0.0023 0.008 0.0108
Brugia malayi putative neuropeptide receptor NPR1 0.0033 0.0182 0.0283
Brugia malayi hypothetical protein 0.0176 0.162 0.2511
Entamoeba histolytica hypothetical protein 0.0039 0.0237 0.0293
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0316 0.049
Brugia malayi sulfakinin receptor protein 0.0033 0.0182 0.0283
Echinococcus granulosus jumonji domain containing 1A 0.0032 0.0174 0.0174
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0032 0.0168 0.0229
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0168 0.0229
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.008 0.0108
Loa Loa (eye worm) hypothetical protein 0.0117 0.1022 0.1584
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0168 0.0229
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.026
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0009 0.0175
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0221 0.2071 0.3211
Brugia malayi photoreceptor-specific nuclear receptor 0.0221 0.2071 0.3211
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0182 0.0182
Echinococcus granulosus sodium channel protein 0.0032 0.0168 0.0168
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0304 0.0414
Trichomonas vaginalis glycogen phosphorylase, putative 0.0557 0.5461 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.012 0.0456
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0623 0.2684
Echinococcus multilocularis microtubule associated protein 2 0.0744 0.7346 0.7346
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0002 0.0004
Schistosoma mansoni inositol monophosphatase 0.0037 0.0216 0.0294
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0182 0.0248
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0237 0.0323
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.008 0.0141
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0221 0.2071 0.3211
Brugia malayi Nuclear hormone receptor-like 1 0.0117 0.1022 0.1584
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0221 0.2071 0.2819
Echinococcus granulosus voltage dependent calcium channel 0.0246 0.2322 0.2322
Echinococcus multilocularis tumor protein p63 0.0364 0.3519 0.3519
Plasmodium falciparum thioredoxin reductase 0.0016 0.0009 0.0098
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0104 0.0896 0.1389
Echinococcus multilocularis sodium leak channel non selective protein 0.0032 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0032 0.0174 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0008 0.0009
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.1096 0.17
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0002 0.0002
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0182 0.0248
Loa Loa (eye worm) voltage-dependent calcium channel 0.0246 0.2322 0.3599
Loa Loa (eye worm) voltage-gated potassium channel 0.0032 0.0168 0.026
Brugia malayi hypothetical protein 0.0104 0.0896 0.1389
Brugia malayi Pre-SET motif family protein 0.0225 0.2115 0.3279
Onchocerca volvulus 0.0023 0.008 0.0142
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0506 0.0506
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0623 0.0623
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0104 0.0896 0.1389
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0177 0.0177
Echinococcus multilocularis thyroid hormone receptor alpha 0.0221 0.2071 0.2071
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0182 0.0248
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0009 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Leishmania major hypothetical protein, conserved 0.0032 0.0174 0.3393
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Schistosoma mansoni amine GPCR 0.0033 0.0182 0.0248
Leishmania major hypothetical protein, conserved 0.0032 0.0168 0.3282
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0015 0.0002 0.0002
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0033 0.0182 0.0283
Echinococcus granulosus small conductance calcium activated potassium 0.0023 0.008 0.008
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0221 0.2071 0.3211
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0182 0.0248
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0182 0.0182
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0416 0.0645
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0095 0.0362
Echinococcus multilocularis two pore calcium channel protein 1 0.0032 0.0168 0.0168
Leishmania major ion transport protein-like protein 0.0023 0.008 0.1555
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0221 0.2071 0.2071
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0023 0.008 0.0123
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0216 0.039
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0221 0.0399
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Loa Loa (eye worm) hypothetical protein 0.0072 0.0573 0.0889
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0006
Onchocerca volvulus 0.0031 0.0158 0.0286
Brugia malayi Nuclear hormone receptor E75 0.0104 0.0896 0.1389
Onchocerca volvulus 0.0109 0.0947 0.1731
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0216 0.082
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0221 0.2071 0.3211
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0002 0.001
Brugia malayi cation channel family protein 0.0032 0.0168 0.026
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0095 0.0148
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.1037 0.4562
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0182 0.0248
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0221 0.2071 0.2071
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0647 0.0647
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0002 0.0003
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0023 0.008 0.0302
Giardia lamblia Hypothetical protein 0.0023 0.008 0.013
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0182 0.0248
Onchocerca volvulus 0.0256 0.2429 0.4445
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0033 0.0182 0.0248
Loa Loa (eye worm) hypothetical protein 0.0104 0.0896 0.1389
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0104 0.0896 0.0896
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0033 0.0182 0.0248
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0655 0.645 0.645
Echinococcus granulosus lamin dm0 0.0029 0.0139 0.0139
Brugia malayi voltage-dependent calcium channel 0.0032 0.0168 0.026
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Loa Loa (eye worm) hypothetical protein 0.0117 0.1022 0.1584
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.012 0.1741
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0033 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Echinococcus granulosus twik family of potassium channels 0.0023 0.008 0.008
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0221 0.2071 0.3211
Schistosoma mansoni hypothetical protein 0.0032 0.0168 0.0229
Echinococcus granulosus Glycosyl transferase family 35 0.0557 0.5461 0.5461
Echinococcus granulosus voltage gated potassium channel 0.0032 0.0168 0.0168
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0177 0.0779
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0225 0.2115 0.3279
Toxoplasma gondii hypothetical protein 0.0032 0.0168 0.0723
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0221 0.0342
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0168 0.0229
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.0258 0.0258
Echinococcus granulosus alpha 1A adrenergic receptor 0.0033 0.0182 0.0182
Onchocerca volvulus 0.0033 0.0182 0.033
Plasmodium vivax JmjC domain containing protein 0.0032 0.0174 0.2531
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Echinococcus multilocularis geminin 0.0359 0.3462 0.3462
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0104 0.0896 0.0896
Brugia malayi G protein-coupled receptor F59B2.13 0.0033 0.0182 0.0283
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0158 0.0245
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0034 0.0191 0.0191
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0009 0.0034
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0009 0.0175
Echinococcus granulosus calcium activated potassium channel 0.0032 0.0168 0.0168
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0032 0.0168 0.0723
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0004
Schistosoma mansoni jumonji domain containing protein 0.0122 0.1074 0.1462
Echinococcus multilocularis conserved hypothetical protein 0.0032 0.0168 0.0168
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0032 0.0168 0.0229
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.012 0.0456
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0023 0.008 0.0302
Brugia malayi G-protein coupled receptor 0.0033 0.0182 0.0283
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0182 0.0182
Schistosoma mansoni glycogen phosphorylase 0.0557 0.5461 0.7433
Echinococcus multilocularis potassium voltage gated channel protein 0.0032 0.0168 0.0168
Leishmania major calcium/potassium channel (CAKC), putative 0.0023 0.008 0.1555
Echinococcus multilocularis voltage gated potassium channel 0.0041 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0104 0.0896 0.1389
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0032 0.0168 0.026
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0037 0.0221 0.0221
Onchocerca volvulus 0.0104 0.0896 0.1637
Toxoplasma gondii transporter, cation channel family protein 0.0032 0.0168 0.0723
Brugia malayi jmjC domain containing protein 0.0122 0.1074 0.1665
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0177 0.0241
Loa Loa (eye worm) solute carrier family 6 member 4 0.0091 0.0766 0.1187
Chlamydia trachomatis glycogen phosphorylase 0.0557 0.5461 1
Schistosoma mansoni adenoreceptor 0.0033 0.0182 0.0248
Brugia malayi hypothetical protein 0.0033 0.0182 0.0283
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0037 0.0221 0.0221
Brugia malayi G protein-coupled receptor 0.0033 0.0182 0.0283
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0004
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0095 0.0419
Echinococcus multilocularis FTZ F1 alpha 0.0221 0.2071 0.2071
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0097 0.0823 0.112
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0512 0.225
Echinococcus granulosus lysine specific demethylase 6a 0.0032 0.0174 0.0174
Onchocerca volvulus 0.0023 0.008 0.0142
Echinococcus multilocularis calcium activated potassium channel variant 0.0023 0.008 0.008
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0512 0.0512
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0032 0.0168 0.026
Echinococcus granulosus voltage dependent calcium channel 0.0655 0.645 0.645
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0221 0.2071 0.3211
Schistosoma mansoni nuclear receptor nhr-48 0.0104 0.0896 0.1219
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0139 0.0216
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0655 0.645 0.645
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0221 0.0399
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0032 0.0168 0.0168
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0032 0.0168 0.0229
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0316 0.0316
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0182 0.0182
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0033 0.0182 0.0283
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0009 0.0034
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0015 0.0002 0.0002
Brugia malayi steroid hormone receptor 0.0221 0.2071 0.3211
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0032 0.0168 0.0168
Onchocerca volvulus 0.0033 0.0182 0.033
Schistosoma mansoni hypothetical protein 0.0033 0.0182 0.0248
Schistosoma mansoni hypothetical protein 0.0039 0.0237 0.0323
Echinococcus multilocularis transient receptor potential cation channel 0.0032 0.0168 0.0168
Brugia malayi nuclear hormone receptor family member nhr-6 0.0104 0.0896 0.1389
Loa Loa (eye worm) hypothetical protein 0.0041 0.0258 0.04
Plasmodium falciparum thioredoxin reductase 0.0047 0.0316 0.4633
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0033 0.0182 0.0182
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0258 0.0351
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0304 0.0471
Schistosoma mansoni voltage-gated potassium channel 0.0073 0.0579 0.0789
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0182 0.0283
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Echinococcus granulosus phd:f box containing protein 0.0032 0.0174 0.0174
Leishmania major hypothetical protein, conserved 0.0027 0.012 0.2348
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0316 0.0316
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0023 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0117 0.1022 0.1584
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.008 0.0108
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0655 0.645 0.878
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0032 0.0168 0.3282
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0221 0.2071 0.3211
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0002 0.0002
Plasmodium falciparum JmjC domain-containing protein, putative 0.0032 0.0174 0.2531
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.0174 0.0748
Loa Loa (eye worm) hypothetical protein 0.0221 0.2071 0.3211
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0023 0.008 0.0123
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0129 0.0491
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0123
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0129 0.1875
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0177 0.0241
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0023 0.008 0.0123
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0106 0.091 0.1411
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0004
Echinococcus multilocularis two pore calcium channel protein 2 0.0032 0.0168 0.0168
Brugia malayi Melatonin receptor type 1A 0.0033 0.0182 0.0283
Echinococcus granulosus short transient receptor potential channel 6 0.0032 0.0169 0.0169
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0023 0.008 0.0302
Brugia malayi ecdysteroid receptor 0.0221 0.2071 0.3211
Entamoeba histolytica hypothetical protein 0.0039 0.0237 0.0293
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0237 0.0237
Brugia malayi Nuclear hormone receptor E75 0.0104 0.0896 0.1389
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0316 0.4633
Echinococcus granulosus FTZ F1 alpha 0.0221 0.2071 0.2071
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0506 0.2226
Schistosoma mansoni hypothetical protein 0.0441 0.4292 0.5842
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0221 0.2071 0.2071
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.0918 0.4036
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0033 0.0182 0.0248
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0139 0.0216
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0428 0.0663
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.0258 0.0258
Schistosoma mansoni thyroid hormone receptor 0.0221 0.2071 0.2819
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0104 0.0896 0.1637
Schistosoma mansoni hypothetical protein 0.0033 0.0182 0.0248
Echinococcus granulosus flap endonuclease 1 0.0028 0.0129 0.0129

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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