Detailed information for compound 1008548

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 526.489 | Formula: C27H26O11
  • H donors: 5 H acceptors: 7 LogP: 3.18 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC[C@H]1O[C@@H](Oc2ccc(cc2COC(=O)c2ccccc2O)O)[C@@H]([C@H]([C@@H]1O)O)OC(=O)c1ccccc1
  • InChi: 1S/C27H26O11/c28-13-21-22(31)23(32)24(38-25(33)15-6-2-1-3-7-15)27(37-21)36-20-11-10-17(29)12-16(20)14-35-26(34)18-8-4-5-9-19(18)30/h1-12,21-24,27-32H,13-14H2/t21-,22-,23+,24-,27-/m1/s1
  • InChiKey: UTRVZPDCXSMOPG-YIHAFMAISA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0054 0.0077 0.0269
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0077 0.0168 0.0861
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0056 0.0084 0.0155
Brugia malayi Cathepsin L-like precursor 0.0223 0.0757 0.2654
Mycobacterium leprae Probable lipase LipE 0.0074 0.0159 0.4653
Mycobacterium ulcerans monoamine oxidase 0.0056 0.0084 0.0366
Entamoeba histolytica cysteine protease, putative 0.0123 0.0353 0.3736
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0159 0.0817
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.0293 0.141
Echinococcus multilocularis transient receptor potential ion channel A 0.0095 0.024 0.024
Schistosoma mansoni hypothetical protein 0.1388 0.5434 1
Entamoeba histolytica cysteine protease, putative 0.0077 0.0168 0.1768
Echinococcus granulosus geminin 0.1388 0.5434 1
Echinococcus granulosus GPCR family 2 0.0128 0.0375 0.069
Schistosoma mansoni transient receptor potential channel 0.0065 0.012 0.0221
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0123 0.0353 0.1237
Plasmodium falciparum glutathione reductase 0.0047 0.005 0.0531
Leishmania major cathepsin L-like protease 0.0269 0.0942 0.9442
Brugia malayi histone deacetylase 1 (HD1) 0.0095 0.0243 0.0852
Entamoeba histolytica cysteine proteinase, putative 0.0269 0.0942 1
Entamoeba histolytica cysteine protease, putative 0.0123 0.0353 0.3736
Toxoplasma gondii histone deacetylase HDAC1 0.0078 0.0172 0.1728
Plasmodium vivax serine-repeat antigen (SERA) 0.0077 0.0168 0.1778
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0056 0.0084 0.0897
Giardia lamblia Cysteine protease 0.0077 0.0168 0.1679
Onchocerca volvulus 0.0269 0.0942 0.7668
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0056 0.0084 0.0847
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0053 0.0072 0.0252
Echinococcus multilocularis short transient receptor potential channel 6 0.0065 0.012 0.012
Trypanosoma brucei oligopeptidase b 0.0054 0.0077 0.0768
Echinococcus multilocularis 0.0056 0.0084 0.0084
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0553 0.208 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0159 0.0293
Leishmania major cathepsin L-like protease 0.0269 0.0942 0.9442
Loa Loa (eye worm) latrophilin receptor protein 2 0.0128 0.0375 0.1315
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0001 0.0004
Leishmania major histone deacetylase, putative 0.0095 0.0243 0.2436
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0077 0.0168 0.1778
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0475 0.1769 0.8503
Entamoeba histolytica cysteine protease, putative 0.0077 0.0168 0.1768
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0269 0.0942 0.4842
Mycobacterium tuberculosis Probable reductase 0.0108 0.0293 0.141
Echinococcus multilocularis histone deacetylase 1 0.0095 0.0243 0.0243
Echinococcus multilocularis integrin alpha 3 0.0113 0.0315 0.0315
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.0342 1
Echinococcus granulosus transient receptor potential ion channel A 0.0095 0.024 0.0442
Schistosoma mansoni hypothetical protein 0.0128 0.0375 0.069
Toxoplasma gondii ABC1 family protein 0.0074 0.0159 0.1593
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0025 0.0045
Loa Loa (eye worm) hypothetical protein 0.0074 0.0159 0.0557
Mycobacterium tuberculosis Conserved protein 0.0074 0.0159 0.0764
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0001 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0269 0.0942 0.4842
Echinococcus multilocularis histone deacetylase 6 0.0078 0.0172 0.0172
Brugia malayi Papain family cysteine protease containing protein 0.0077 0.0168 0.0587
Trichomonas vaginalis glucosylceramidase, putative 0.0341 0.1228 0.6314
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0089 0.0945
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0269 0.0942 0.4842
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0269 0.0942 0.4842
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0054 0.0077 0.0269
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.005 0.0531
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0269 0.0942 1
Giardia lamblia Cathepsin B precursor 0.0283 0.0998 1
Onchocerca volvulus 0.0049 0.0055 0.0448
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0001 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0123 0.0353 0.3535
Trichomonas vaginalis glucosylceramidase, putative 0.0359 0.1302 0.6693
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.0496 0.1738
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0159 0.0764
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.0342 0.1642
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0056 0.0084 0.0897
Entamoeba histolytica cysteine proteinase, putative 0.0123 0.0353 0.3736
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0128 0.0375 0.069
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0238 0.0815 0.286
Brugia malayi Cathepsin L-like precursor 0.0269 0.0942 0.3303
Brugia malayi hypothetical protein 0.0065 0.0123 0.0431
Brugia malayi fibroinase precursor 0.0077 0.0168 0.0587
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0168 0.0861
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0269 0.0942 0.4842
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0396 0.1449 0.1449
Loa Loa (eye worm) hypothetical protein 0.0745 0.2852 1
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0077 0.0168 0.1778
Loa Loa (eye worm) hypothetical protein 0.0049 0.0055 0.0193
Onchocerca volvulus 0.0269 0.0942 0.7668
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0269 0.0942 0.4842
Leishmania major UDP-galactopyranose mutase 0.0056 0.0084 0.0847
Schistosoma mansoni hypothetical protein 0.0128 0.0375 0.069
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0077 0.0168 0.0861
Toxoplasma gondii histone deacetylase HDAC4 0.0049 0.0058 0.0577
Trichomonas vaginalis histone deacetylase, putative 0.0095 0.0243 0.1249
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0123 0.0353 0.0649
Echinococcus multilocularis protoporphyrinogen oxidase 0.0056 0.0084 0.0084
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0283 0.0998 1
Brugia malayi Histone deacetylase family protein 0.0078 0.0172 0.0604
Leishmania major cathepsin L-like protease 0.0269 0.0942 0.9442
Onchocerca volvulus Matrix metalloproteinase homolog 0.0096 0.0246 0.2
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0089 0.0312
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.0293 0.141
Onchocerca volvulus 0.0269 0.0942 0.7668
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0102 0.0188
Echinococcus granulosus cathepsin b 0.0745 0.2852 0.5248
Entamoeba histolytica cysteine proteinase, putative 0.0123 0.0353 0.3736
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0001 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0269 0.0942 0.9442
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0097 0.0252 0.2049
Brugia malayi hypothetical protein 0.0101 0.0267 0.0937
Leishmania major cysteine peptidase A (CPA) 0.0269 0.0942 0.9442
Schistosoma mansoni transient receptor potential channel 0.0065 0.012 0.0221
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.016 0.1604
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0025 0.0045
Loa Loa (eye worm) histone deacetylase 0.0078 0.0172 0.0604
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0745 0.2852 0.5248
Loa Loa (eye worm) hypothetical protein 0.0074 0.0159 0.0557
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0056 0.0084 0.0366
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0046 0.0045 0.0159
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.0496 0.1738
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0238 0.0815 0.1501
Loa Loa (eye worm) matrixin family protein 0.0096 0.0246 0.0861
Entamoeba histolytica cysteine protease, putative 0.0123 0.0353 0.3736
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.005 0.005
Brugia malayi Cathepsin L-like cysteine proteinase 0.0223 0.0757 0.2654
Entamoeba histolytica cysteine protease, putative 0.0123 0.0353 0.3736
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0102 0.0442
Loa Loa (eye worm) hypothetical protein 0.0095 0.0243 0.0852
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0102 0.0442
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0277 0.0972 0.341
Brugia malayi Papain family cysteine protease containing protein 0.0077 0.0168 0.0587
Schistosoma mansoni histone deacetylase 0.0095 0.0243 0.0447
Brugia malayi Papain family cysteine protease containing protein 0.0123 0.0353 0.1237
Entamoeba histolytica cysteine protease, putative 0.0123 0.0353 0.3736
Echinococcus granulosus high affinity choline transporter 1 0.034 0.1225 0.2254
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.005 0.0176
Echinococcus granulosus histone deacetylase 6 0.0084 0.0198 0.0363
Giardia lamblia Cathepsin L precursor 0.0077 0.0168 0.1679
Mycobacterium leprae PROBABLE HYDROLASE 0.0053 0.0072 0.2104
Entamoeba histolytica cysteine protease, putative 0.0123 0.0353 0.3736
Schistosoma mansoni histone deacetylase 1 2 3 0.0049 0.0058 0.0106
Echinococcus granulosus histone deacetylase 0.0078 0.0172 0.0317
Loa Loa (eye worm) hypothetical protein 0.0077 0.0168 0.0587
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0097 0.0252 0.0463
Brugia malayi beta-lactamase 0.0074 0.0159 0.0557
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0102 0.0442
Loa Loa (eye worm) beta-lactamase 0.0074 0.0159 0.0557
Giardia lamblia Cathepsin L precursor 0.0077 0.0168 0.1679
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0045 0.0043 0.0079
Brugia malayi Calcitonin receptor-like protein seb-1 0.0405 0.1487 0.5215
Plasmodium vivax vivapain-2 0.0269 0.0942 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0089 0.0386
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0089 0.0945
Schistosoma mansoni hypothetical protein 0.0061 0.0107 0.0196
Loa Loa (eye worm) mbt repeat family protein 0.0097 0.0252 0.0883
Plasmodium vivax histone deacetylase, putative 0.0078 0.0172 0.183
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0269 0.0942 0.4842
Loa Loa (eye worm) hypothetical protein 0.0095 0.0243 0.0853
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0745 0.2852 0.5248
Echinococcus multilocularis histone acetyltransferase MYST2 0.0111 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0062 0.0108 0.0378
Brugia malayi CHE-14 protein 0.0041 0.0025 0.0086
Echinococcus granulosus cathepsin L 0.0123 0.0353 0.0649
Echinococcus granulosus cathepsin l1 0.0223 0.0757 0.1393
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0111 0.0306 0.0306
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0077 0.0168 0.0861
Trichomonas vaginalis glucosylceramidase, putative 0.0519 0.1946 1
Loa Loa (eye worm) inositol-1 0.0075 0.016 0.0561
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0238 0.0815 0.0815
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0269 0.0942 0.4842
Echinococcus granulosus expressed conserved protein 0.009 0.022 0.0405
Loa Loa (eye worm) hypothetical protein 0.0223 0.0757 0.2654
Echinococcus multilocularis cathepsin L 0.0123 0.0353 0.0353
Entamoeba histolytica cysteine protease, putative 0.0077 0.0168 0.1768
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.0293 0.141
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0077 0.0168 0.0861
Schistosoma mansoni hypothetical protein 0.0128 0.0375 0.069
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0095 0.0243 0.1249
Loa Loa (eye worm) hypothetical protein 0.0111 0.0306 0.1073
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0269 0.0942 0.4842
Echinococcus granulosus cathepsin L cysteine protease 0.0123 0.0353 0.0649
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0111 0.0304 0.0304
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0269 0.0942 0.4842
Trypanosoma cruzi histone deacetylase, putative 0.0049 0.0058 0.0202
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0077 0.0168 0.1778
Trypanosoma brucei prolyl oligopeptidase, putative 0.0054 0.0077 0.0768
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0077 0.0168 0.1778
Leishmania major cathepsin L-like protease 0.0269 0.0942 0.9442
Loa Loa (eye worm) hypothetical protein 0.0074 0.0159 0.0557
Loa Loa (eye worm) hypothetical protein 0.0116 0.0328 0.1149
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0077 0.0168 0.1768
Loa Loa (eye worm) hypothetical protein 0.0046 0.0045 0.0159
Loa Loa (eye worm) transcription factor SMAD2 0.0372 0.1353 0.4746
Toxoplasma gondii preprocathepsin c precursor, putative 0.0077 0.0168 0.1679
Brugia malayi POT family protein 0.0041 0.0026 0.009
Mycobacterium tuberculosis Conserved protein 0.0074 0.0159 0.0764
Brugia malayi Histone deacetylase 1 0.0095 0.0243 0.0852
Entamoeba histolytica cysteine protease, putative 0.0123 0.0353 0.3736
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0056 0.0084 0.0897
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0037 0.0011 0.002
Schistosoma mansoni ap endonuclease 0.0057 0.0089 0.0164
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.0243 0.2574
Giardia lamblia Encystation-specific protease 0.0077 0.0168 0.1679
Mycobacterium ulcerans lipase LipD 0.0074 0.0159 0.069
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0102 0.0102
Loa Loa (eye worm) MBCTL1 0.0111 0.0306 0.1073
Schistosoma mansoni cathepsin F (C01 family) 0.0269 0.0942 0.1734
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0157 0.0492 0.0492
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0102 0.049
Plasmodium vivax vivapain-3 0.0123 0.0353 0.3744
Loa Loa (eye worm) hypothetical protein 0.0037 0.0011 0.0038
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0046 0.0045 0.0159
Onchocerca volvulus 0.0077 0.0168 0.1364
Schistosoma mansoni hypothetical protein 0.1388 0.5434 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0168 0.0587
Plasmodium vivax hypothetical protein, conserved 0.0056 0.0084 0.0897
Onchocerca volvulus 0.0269 0.0942 0.7668
Trypanosoma cruzi histone deacetylase, putative 0.0078 0.0172 0.0604
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0159 0.0764
Toxoplasma gondii LsmAD domain-containing protein 0.0101 0.0267 0.2677
Trichomonas vaginalis glucosylceramidase, putative 0.0341 0.1228 0.6314
Trichomonas vaginalis glucosylceramidase, putative 0.0519 0.1946 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0269 0.0942 0.4842
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0037 0.0011 0.0011
Brugia malayi cathepsin Z-like cysteine proteinase 0.0077 0.0168 0.0587
Echinococcus granulosus sodium:myo inositol cotransporter 0.0037 0.0011 0.002
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.0496 0.0912
Plasmodium falciparum serine repeat antigen 6 0.0077 0.0168 0.1778
Onchocerca volvulus Glucosylceramidase homolog 0.0341 0.1228 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0075 0.016 0.0694
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0077 0.0168 0.1778
Onchocerca volvulus 0.0097 0.0252 0.2049
Trypanosoma cruzi cysteine peptidase, putative 0.0269 0.0942 0.3303
Onchocerca volvulus 0.0116 0.0328 0.2667
Chlamydia trachomatis protoporphyrinogen oxidase 0.0056 0.0084 1
Onchocerca volvulus Cathepsin F homolog 0.0269 0.0942 0.7668
Leishmania major cathepsin L-like protease 0.0269 0.0942 0.9442
Giardia lamblia Cysteine protease 0.0077 0.0168 0.1679
Brugia malayi cathepsin Z-like cysteine proteinase 0.0077 0.0168 0.0587
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.0293 0.141
Mycobacterium tuberculosis Conserved hypothetical protein 0.0056 0.0084 0.0406
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0269 0.0942 0.9442
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0077 0.0168 0.1778
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0055 0.0101
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0238 0.0815 0.1501
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0025 0.0086
Trypanosoma cruzi histone deacetylase 1, putative 0.0095 0.0243 0.0852
Onchocerca volvulus 0.0074 0.0159 0.1294
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0067 0.0129 0.0618
Plasmodium falciparum thioredoxin reductase 0.0047 0.005 0.0531
Mycobacterium tuberculosis Probable peptidase 0.0054 0.0077 0.0368
Brugia malayi cathepsin F-like cysteine proteinase 0.0077 0.0168 0.0587
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0077 0.0168 0.1778
Trypanosoma brucei PAB1-binding protein , putative 0.0101 0.0267 0.2677
Echinococcus multilocularis integrin alpha ps 0.0066 0.0126 0.0126
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0159 0.0557
Toxoplasma gondii histone deacetylase HDAC2 0.0095 0.0243 0.2436
Plasmodium vivax histone deacetylase 2, putative 0.0078 0.0172 0.183
Mycobacterium tuberculosis Conserved protein 0.0074 0.0159 0.0764
Schistosoma mansoni myelin transcription factor 1 myt1 0.0111 0.0306 0.0563
Entamoeba histolytica histone deacetylase, putative 0.0095 0.0243 0.257
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0159 0.0293
Entamoeba histolytica cysteine proteinase, putative 0.0123 0.0353 0.3736
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0159 0.0764
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.0243 0.0448
Echinococcus granulosus sodium:glucose cotransporter 0.0037 0.0011 0.002
Trichomonas vaginalis histone deacetylase, putative 0.0095 0.0243 0.1249
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0269 0.0942 0.3303
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0159 0.0817
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0077 0.0168 0.1778
Schistosoma mansoni patched 1 0.0041 0.0025 0.0045
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0089 0.0089
Loa Loa (eye worm) histone deacetylase 1 0.0095 0.0243 0.0852
Plasmodium vivax ataxin-2 like protein, putative 0.0101 0.0267 0.2835
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0077 0.0168 0.0861
Plasmodium vivax unspecified product 0.0077 0.0168 0.1778
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0077 0.0168 0.0861
Schistosoma mansoni hypothetical protein 0.0039 0.0019 0.0034
Plasmodium vivax serine-repeat antigen (SERA) 0.0077 0.0168 0.1778
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0159 0.069
Schistosoma mansoni hypothetical protein 0.0604 0.2286 0.4208
Loa Loa (eye worm) hypothetical protein 0.0098 0.0253 0.0889
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0056 0.0084 0.2472
Echinococcus multilocularis short transient receptor potential channel 6 0.0065 0.012 0.012
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0001 0.0002
Echinococcus multilocularis prolyl endopeptidase 0.0136 0.0404 0.0404
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0089 0.0933
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0159 0.0764
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0157 0.0492 0.0906
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0269 0.0942 0.9442
Echinococcus granulosus integrin alpha ps 0.0066 0.0126 0.0232
Loa Loa (eye worm) hypothetical protein 0.0074 0.0159 0.0557
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0075 0.016 0.1688
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0077 0.0168 0.0308
Trypanosoma cruzi cysteine proteinase, putative 0.0123 0.0353 0.1237
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0159 0.0557
Schistosoma mansoni sex comb on midleg homolog 0.0097 0.0252 0.0463
Schistosoma mansoni hypothetical protein 0.0039 0.0019 0.0034
Loa Loa (eye worm) hypothetical protein 0.0049 0.0058 0.0202
Leishmania major oligopeptidase b 0.0054 0.0077 0.0768
Trypanosoma cruzi histone deacetylase 1, putative 0.0095 0.0243 0.0852
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0159 0.4653
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0045 0.0043 0.0043
Onchocerca volvulus Histone deacetylase 10 homolog 0.0049 0.0058 0.0469
Plasmodium vivax vivapain-1 0.0123 0.0353 0.3744
Loa Loa (eye worm) hypothetical protein 0.0223 0.0757 0.2654
Loa Loa (eye worm) hypothetical protein 0.005 0.0062 0.0216
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0036 0.0006 0.0006
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0396 0.1449 0.2667
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0077 0.0168 0.0587
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0102 0.0188
Echinococcus multilocularis integrin alpha ps 0.0066 0.0126 0.0126
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0077 0.0168 0.1778
Giardia lamblia Cathepsin L precursor 0.0077 0.0168 0.1679
Loa Loa (eye worm) hypothetical protein 0.0046 0.0045 0.0159
Loa Loa (eye worm) histone deacetylase 11 0.0049 0.0058 0.0202
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0077 0.0168 0.1679
Leishmania major histone deacetylase, putative 0.0095 0.0243 0.2436
Echinococcus granulosus short transient receptor potential channel 6 0.0065 0.012 0.0221
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.016 0.0561
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0159 0.0817
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.0243 0.0853
Onchocerca volvulus Matrilysin homolog 0.0096 0.0246 0.2
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0089 0.0312
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0001 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0269 0.0942 0.4842
Giardia lamblia Cathepsin L precursor 0.0077 0.0168 0.1679
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0001 0.0012
Plasmodium vivax glutathione reductase, putative 0.0047 0.005 0.0531
Brugia malayi Transient-receptor-potential like protein 0.0036 0.0006 0.0023
Trichomonas vaginalis esterase, putative 0.0074 0.0159 0.0817
Schistosoma mansoni histone deacetylase hda2 0.0049 0.0058 0.0106
Toxoplasma gondii exonuclease III APE 0.0057 0.0089 0.0892
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0269 0.0942 0.9442
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0077 0.0168 0.0308
Plasmodium falciparum histone deacetylase 2 0.0078 0.0172 0.183
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.0293 0.141
Trichomonas vaginalis glucosylceramidase, putative 0.0341 0.1228 0.6314
Toxoplasma gondii histone lysine-specific demethylase 0.0056 0.0084 0.0847
Loa Loa (eye worm) hypothetical protein 0.0112 0.0309 0.1083
Onchocerca volvulus 0.0037 0.0011 0.0087
Trypanosoma cruzi cysteine protease, putative 0.0123 0.0353 0.1237
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0267 0.2835
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.0342 0.1642
Loa Loa (eye worm) matrix metalloproteinase 0.0043 0.0034 0.0119
Entamoeba histolytica cysteine protease, putative 0.0123 0.0353 0.3736
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0054 0.0077 0.0768
Trypanosoma cruzi cysteine proteinase, putative 0.0123 0.0353 0.1237
Giardia lamblia Cathepsin L-like protease 0.0077 0.0168 0.1679
Trichomonas vaginalis histone deacetylase, putative 0.0095 0.0243 0.1249
Echinococcus multilocularis protein dispatched 1 0.0047 0.0048 0.0048
Trypanosoma cruzi UDP-galactopyranose mutase 0.0056 0.0084 0.0296
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0037 0.0011 0.0011
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0136 0.0404 0.0744
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0077 0.0168 0.1679
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0075 0.016 0.0823
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0238 0.0815 0.0815
Echinococcus granulosus SAM and MBT domain containing protein 0.0097 0.0252 0.0463
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0757 0.389
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0269 0.0942 0.9442
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0121 0.0347 0.167
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.0408 0.0408
Loa Loa (eye worm) hypothetical protein 0.0077 0.0168 0.0587
Entamoeba histolytica cysteine proteinase, putative 0.0223 0.0757 0.8032
Echinococcus multilocularis inositol monophosphatase 1 0.0075 0.016 0.016
Giardia lamblia Cathepsin B precursor 0.0077 0.0168 0.1679
Echinococcus multilocularis expressed conserved protein 0.009 0.022 0.022
Brugia malayi Matrixin family protein 0.0043 0.0034 0.0119
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0077 0.0168 0.1778
Schistosoma mansoni transient receptor potential channel 0.0098 0.0253 0.0466
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0077 0.0168 0.0308
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0077 0.0168 0.0587
Toxoplasma gondii thioredoxin reductase 0.0047 0.005 0.0502
Giardia lamblia Hypothetical protein 0.0077 0.0168 0.1679
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0269 0.0942 0.4842
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0123 0.0353 0.0649
Trypanosoma cruzi histone deacetylase, putative 0.0049 0.0058 0.0202
Entamoeba histolytica cysteine protease, putative 0.0269 0.0942 1
Trypanosoma cruzi cysteine peptidase, putative 0.0046 0.0045 0.0159
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0269 0.0942 0.9442
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0159 0.0557
Trichomonas vaginalis glucosylceramidase, putative 0.0341 0.1228 0.6314
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0102 0.1022
Trypanosoma cruzi cruzipain precursor, putative 0.0046 0.0045 0.0159
Onchocerca volvulus Cathepsin L homolog 0.0269 0.0942 0.7668
Loa Loa (eye worm) hypothetical protein 0.0116 0.0326 0.1143
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0123 0.0353 0.0649
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0745 0.2852 1
Trypanosoma cruzi cysteine peptidase, putative 0.0269 0.0942 0.3303
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0077 0.0168 0.0861
Echinococcus multilocularis GPCR, family 2 0.0128 0.0375 0.0375
Trichomonas vaginalis glucosylceramidase, putative 0.0519 0.1946 1
Brugia malayi mbt repeat family protein 0.0097 0.0252 0.0883
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0001 0.0004
Echinococcus multilocularis histone deacetylase 3 0.0095 0.0243 0.0243
Schistosoma mansoni histone deacetylase hda2 0.0084 0.0198 0.0363
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.016 0.0561
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0269 0.0942 0.0942
Trypanosoma brucei trypanothione reductase 0.0047 0.005 0.0502
Echinococcus multilocularis histone deacetylase 0.0078 0.0172 0.0172
Brugia malayi latrophilin 2 splice variant baaae 0.0277 0.0972 0.341
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0159 0.0817
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0054 0.0077 0.0768
Giardia lamblia Histone deacetylase 0.0095 0.0243 0.2436
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0095 0.0243 0.1249
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0159 0.0159
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0159 0.0293
Trichomonas vaginalis histone deacetylase, putative 0.0095 0.0243 0.1249
Giardia lamblia Cathepsin B precursor 0.0077 0.0168 0.1679
Loa Loa (eye worm) hypothetical protein 0.0223 0.0757 0.2654
Loa Loa (eye worm) hypothetical protein 0.0056 0.0084 0.0296
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0077 0.0168 0.0587
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0001 0.0001
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0102 0.0188
Trypanosoma cruzi histone deacetylase, putative 0.0078 0.0172 0.0604
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0089 0.0428
Echinococcus multilocularis cysteine protease 0.0269 0.0942 0.0942
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0159 0.069
Toxoplasma gondii cathepsin CPL 0.0269 0.0942 0.9442
Mycobacterium ulcerans beta-lactamase 0.0074 0.0159 0.069
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0001 0.0006
Entamoeba histolytica cysteine protease, putative 0.0077 0.0168 0.1768
Giardia lamblia Cathepsin L-like protease 0.0077 0.0168 0.1679
Schistosoma mansoni alpha glucosidase 0.0035 0.0001 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0238 0.0815 0.1501
Toxoplasma gondii cathepsin CPC2 0.0077 0.0168 0.1679
Schistosoma mansoni histone deacetylase 4 5 0.0078 0.0172 0.0317
Echinococcus granulosus sodium:glucose cotransporter 2 0.0037 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0111 0.0304 0.1067
Onchocerca volvulus 0.0074 0.0159 0.1294
Giardia lamblia Cathepsin L precursor 0.0077 0.0168 0.1679
Echinococcus granulosus lysine specific histone demethylase 1A 0.0111 0.0304 0.056
Echinococcus multilocularis cysteine protease 0.0269 0.0942 0.0942
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0269 0.0942 0.4842
Schistosoma mansoni hypothetical protein 0.0045 0.0043 0.0079
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0077 0.0168 0.0308
Giardia lamblia Cysteine protease 0.0077 0.0168 0.1679
Brugia malayi amine oxidase, flavin-containing family protein 0.0062 0.0108 0.0378
Schistosoma mansoni integrin alpha 0.0148 0.0453 0.0835
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0269 0.0942 0.4842
Loa Loa (eye worm) histone deacetylase 7A 0.0078 0.0172 0.0604
Schistosoma mansoni inositol monophosphatase 0.0075 0.016 0.0295
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0075 0.016 0.1604
Giardia lamblia Cysteine protease 0.0077 0.0168 0.1679
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0283 0.0998 0.1836
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0269 0.0942 0.0942
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0136 0.0404 0.4054
Echinococcus granulosus transient receptor potential gamma protein 0.0098 0.0253 0.0466
Entamoeba histolytica cysteine protease, putative 0.0123 0.0353 0.3736
Brugia malayi hypothetical protein 0.0056 0.0084 0.0296
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.016 0.1604
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0267 0.2835
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0223 0.0757 0.2654
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0405 0.1487 0.5215
Toxoplasma gondii cathepsin CPC1 0.0077 0.0168 0.1679
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0095 0.0243 0.1249
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0128 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0041 0.0025 0.0086
Echinococcus granulosus histone acetyltransferase MYST2 0.0111 0.0306 0.0563
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0159 0.0817
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0269 0.0942 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0077 0.0168 0.0861
Entamoeba histolytica cysteine protease, putative 0.0123 0.0353 0.3736
Brugia malayi Cathepsin L-like precursor 0.0269 0.0942 0.3303
Loa Loa (eye worm) hypothetical protein 0.0269 0.0942 0.3303
Entamoeba histolytica cysteine protease, putative 0.0123 0.0353 0.3736
Plasmodium falciparum histone deacetylase 1 0.0095 0.0243 0.258
Brugia malayi glutathione reductase 0.0047 0.005 0.0176
Plasmodium vivax histone deacetylase, putative 0.0049 0.0058 0.0611
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0054 0.0077 0.0368
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0269 0.0942 0.4842
Echinococcus granulosus integrin alpha 3 0.0113 0.0315 0.058
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0128 0.0375 0.1315
Brugia malayi Cathepsin L-like precursor 0.0269 0.0942 0.3303
Loa Loa (eye worm) hypothetical protein 0.0043 0.0034 0.0119
Schistosoma mansoni alpha-glucosidase 0.0136 0.0407 0.0749
Echinococcus multilocularis tumor protein p63 0.0332 0.1192 0.1192
Schistosoma mansoni integrin alpha-ps 0.0066 0.0126 0.0232
Trichomonas vaginalis glucosylceramidase, putative 0.0341 0.1228 0.6314
Brugia malayi Inositol-1 0.0075 0.016 0.0561
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0067 0.0129 0.3765
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0077 0.0168 0.0308
Echinococcus granulosus histone deacetylase 8 0.0049 0.0058 0.0106
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0238 0.0815 0.1501
Brugia malayi Papain family cysteine protease containing protein 0.0077 0.0168 0.0587
Echinococcus granulosus histone deacetylase 1 0.0095 0.0243 0.0447
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0001 0.0006
Plasmodium vivax histone deacetylase 1, putative 0.0095 0.0243 0.258
Schistosoma mansoni cathepsin C 0.0077 0.0168 0.0308
Schistosoma mansoni hypothetical protein 0.0277 0.0972 0.179
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0001 0.0004
Echinococcus granulosus tumor protein p63 0.0332 0.1192 0.2193
Brugia malayi beta-lactamase family protein 0.0074 0.0159 0.0557
Trypanosoma cruzi oligopeptidase b 0.0054 0.0077 0.0269
Giardia lamblia Hypothetical protein 0.0077 0.0168 0.1679
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0111 0.0306 0.0563
Giardia lamblia Cathepsin B precursor 0.0077 0.0168 0.1679
Onchocerca volvulus 0.0223 0.0757 0.6161
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0077 0.0168 0.1679
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.005 0.0092
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0269 0.0942 0.9442
Trichomonas vaginalis glucosylceramidase, putative 0.0341 0.1228 0.6314
Echinococcus granulosus histone deacetylase 7 0.0078 0.0172 0.0317
Toxoplasma gondii prolyl endopeptidase 0.0136 0.0404 0.4054
Entamoeba histolytica hypothetical protein 0.0077 0.0168 0.1768
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0519 0.1946 0.6823
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0353 0.1813
Loa Loa (eye worm) hypothetical protein 0.0061 0.0107 0.0376
Schistosoma mansoni cathepsin s 0.0046 0.0045 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0353 0.1813
Brugia malayi Cathepsin L-like precursor 0.0046 0.0045 0.0159
Plasmodium falciparum serine repeat antigen 5 0.0077 0.0168 0.1778
Echinococcus granulosus short transient receptor potential channel 6 0.0065 0.012 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0757 0.389
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0089 0.0312
Plasmodium falciparum serine repeat antigen 7 0.0077 0.0168 0.1778
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0269 0.0942 0.4842
Schistosoma mansoni hypothetical protein 0.0039 0.0019 0.0034
Loa Loa (eye worm) cathepsin B 0.0283 0.0998 0.3499
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0111 0.0304 0.056
Echinococcus granulosus cathepsin L cysteine proteinase 0.0269 0.0942 0.1734
Plasmodium vivax vivapain-2 0.0269 0.0942 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0267 0.0937
Entamoeba histolytica cysteine proteinase 1, putative 0.0123 0.0353 0.3736
Echinococcus granulosus inositol monophosphatase 1 0.0075 0.016 0.0295
Onchocerca volvulus 0.0092 0.0228 0.1853
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0077 0.0168 0.1778
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0745 0.2852 0.5248
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0075 0.016 1
Giardia lamblia Cathepsin B precursor 0.0283 0.0998 1
Leishmania major hypothetical protein, conserved 0.0074 0.0159 0.1593
Echinococcus granulosus solute carrier family 5 0.0037 0.0011 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0168 0.0861
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0496 0.0496
Plasmodium falciparum cysteine proteinase falcipain 1 0.0123 0.0353 0.3744
Onchocerca volvulus Prolyl endopeptidase homolog 0.0136 0.0404 0.3292
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0609 0.2305 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0267 0.0937
Plasmodium falciparum protoporphyrinogen oxidase 0.0056 0.0084 0.0897
Leishmania major cathepsin L-like protease 0.0269 0.0942 0.9442
Brugia malayi cathepsin F-like cysteine proteinase 0.0046 0.0045 0.0159
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0089 0.0892
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0159 0.0557
Trichomonas vaginalis inositol monophosphatase, putative 0.0075 0.016 0.0823
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0238 0.0815 0.1501
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.005 0.0241
Echinococcus granulosus cathepsin l1 0.0269 0.0942 0.1734
Schistosoma mansoni inositol transporter 0.0037 0.0011 0.002
Brugia malayi Papain family cysteine protease containing protein 0.0269 0.0942 0.3303
Loa Loa (eye worm) histone deacetylase 3 0.0095 0.0243 0.0852
Brugia malayi Cathepsin L-like precursor 0.0269 0.0942 0.3303
Brugia malayi Latrophilin receptor protein 2 0.0128 0.0375 0.1315
Mycobacterium ulcerans hypothetical protein 0.0074 0.0159 0.069
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0159 0.1593
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0056 0.0084 0.0897
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0077 0.0168 0.1679
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0077 0.0168 0.0861
Entamoeba histolytica cysteine proteinase, putative 0.0269 0.0942 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0077 0.0168 0.0308
Trypanosoma brucei cysteine peptidase C (CPC) 0.0283 0.0998 1
Echinococcus multilocularis polycomb protein SCMH1 0.0097 0.0252 0.0252
Onchocerca volvulus 0.0074 0.0159 0.1294
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0001 0.0004
Schistosoma mansoni high-affinity choline transporter 0.034 0.1225 0.2254
Onchocerca volvulus Matrilysin homolog 0.0043 0.0034 0.0277
Plasmodium falciparum serine repeat antigen 3 0.0077 0.0168 0.1778
Loa Loa (eye worm) hypothetical protein 0.0128 0.0375 0.1315
Loa Loa (eye worm) fibroinase 0.0269 0.0942 0.3303
Brugia malayi cathepsin B-like cysteine proteinase 0.0745 0.2852 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0269 0.0942 0.4842
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0089 0.0312
Entamoeba histolytica cysteine protease, putative 0.0123 0.0353 0.3736
Schistosoma mansoni amine oxidase 0.0056 0.0084 0.0155
Schistosoma mansoni hypothetical protein 0.0039 0.0019 0.0034
Brugia malayi Matrixin family protein 0.0105 0.028 0.0983
Brugia malayi mbt repeat family protein 0.0097 0.0252 0.0883
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0089 0.5
Entamoeba histolytica cysteine proteinase, putative 0.0123 0.0353 0.3736
Brugia malayi Cathepsin L-like precursor 0.0269 0.0942 0.3303
Brugia malayi Cathepsin L-like precursor 0.0269 0.0942 0.3303
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0025 0.0025
Onchocerca volvulus 0.0061 0.0107 0.0868
Echinococcus granulosus cathepsin L 0.0077 0.0168 0.0308
Loa Loa (eye worm) glutathione reductase 0.0047 0.005 0.0176
Schistosoma mansoni cathepsin F (C01 family) 0.0269 0.0942 0.1734
Trypanosoma brucei histone deacetylase 4 0.0078 0.0172 0.1728
Trypanosoma cruzi oligopeptidase b 0.0054 0.0077 0.0269
Onchocerca volvulus Cathepsin L homolog 0.0077 0.0168 0.1364
Brugia malayi histone deacetylase 11 0.0049 0.0058 0.0202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0269 0.0942 0.4842
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0037 0.0011 0.0107
Entamoeba histolytica cysteine protease, putative 0.0077 0.0168 0.1768
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0128 0.0375 0.069
Onchocerca volvulus Cathepsin L homolog 0.0269 0.0942 0.7668
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0283 0.0998 0.5128
Loa Loa (eye worm) hypothetical protein 0.0082 0.0187 0.0658
Entamoeba histolytica cysteine protease, putative 0.0077 0.0168 0.1768
Echinococcus multilocularis protein patched 0.0041 0.0025 0.0025
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0609 0.2305 1
Giardia lamblia Cathepsin B precursor 0.0077 0.0168 0.1679
Brugia malayi cathepsin L precursor 0.0077 0.0168 0.0587
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0077 0.0168 0.0861
Echinococcus multilocularis cathepsin b 0.0745 0.2852 0.2852
Loa Loa (eye worm) hypothetical protein 0.0111 0.0304 0.1067
Loa Loa (eye worm) MH2 domain-containing protein 0.0372 0.1353 0.4746
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0269 0.0942 0.4842
Brugia malayi prolyl oligopeptidase family protein 0.0136 0.0404 0.1418
Trypanosoma cruzi major cysteine proteinase, putative 0.0077 0.0168 0.0587
Loa Loa (eye worm) hypothetical protein 0.0077 0.0168 0.0587
Echinococcus multilocularis high affinity choline transporter 1 0.034 0.1225 0.1225
Toxoplasma gondii cathepsin B 0.0283 0.0998 1
Trypanosoma cruzi cysteine peptidase, putative 0.0269 0.0942 0.3303
Loa Loa (eye worm) integrin alpha pat-2 0.0228 0.0775 0.2717
Echinococcus granulosus cysteine protease 0.0123 0.0353 0.0649
Loa Loa (eye worm) ctsf protein 0.0269 0.0942 0.3303
Onchocerca volvulus 0.0269 0.0942 0.7668
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0128 0.0375 0.0375
Echinococcus granulosus cathepsin b 0.0745 0.2852 0.5248
Echinococcus multilocularis solute carrier family 5 0.0037 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0077 0.0168 0.0861
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0054 0.0077 0.0333
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.0408 0.075
Trichomonas vaginalis glucosylceramidase, putative 0.0519 0.1946 1
Echinococcus multilocularis cathepsin b 0.0745 0.2852 0.2852
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0159 0.0764
Schistosoma mansoni inositol monophosphatase 0.0075 0.016 0.0295
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0249 0.0459
Mycobacterium ulcerans hydrolase 0.0053 0.0072 0.0312
Trypanosoma brucei histone deacetylase 2 0.0049 0.0058 0.0577
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0269 0.0942 0.4842
Trypanosoma cruzi cysteine peptidase, putative 0.0123 0.0353 0.1237
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0077 0.0168 0.0861
Echinococcus multilocularis cathepsin L 0.0077 0.0168 0.0168
Echinococcus multilocularis SAM and MBT domain containing protein 0.0097 0.0252 0.0252
Trichomonas vaginalis glucosylceramidase, putative 0.0519 0.1946 1
Brugia malayi Cathepsin L-like precursor 0.0223 0.0757 0.2654
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0269 0.0942 0.9442
Brugia malayi SWIRM domain containing protein 0.0116 0.0328 0.1149
Plasmodium vivax hypothetical protein, conserved 0.0056 0.0084 0.0897
Trichomonas vaginalis glucosylceramidase, putative 0.0359 0.1302 0.6693
Plasmodium falciparum serine repeat antigen 8 0.0077 0.0168 0.1778
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0283 0.0998 0.3499
Brugia malayi cathepsin L-like precursor 0.0223 0.0757 0.2654
Trypanosoma cruzi major cysteine proteinase, putative 0.0077 0.0168 0.0587
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0089 0.0892
Echinococcus multilocularis transient receptor potential gamma protein 0.0098 0.0253 0.0253
Schistosoma mansoni sex comb on midleg homolog 0.0097 0.0252 0.0463
Schistosoma mansoni amine oxidase 0.0056 0.0084 0.0155
Loa Loa (eye worm) cysteine protease 0.0269 0.0942 0.3303
Brugia malayi Sodium:solute symporter family protein 0.0037 0.0011 0.0038
Plasmodium vivax unspecified product 0.0123 0.0353 0.3744
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0269 0.0942 0.3303
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0037 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0077 0.0168 0.0861
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0089 0.0457
Schistosoma mansoni cathepsin B (C01 family) 0.0077 0.0168 0.0308
Loa Loa (eye worm) POT family protein 0.0041 0.0026 0.009
Schistosoma mansoni transient receptor potential channel 4 0.0098 0.0253 0.0466
Brugia malayi MH2 domain containing protein 0.0372 0.1353 0.4746
Brugia malayi beta-lactamase family protein 0.0074 0.0159 0.0557
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.0342 0.1642
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0238 0.0815 0.286
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0075 0.016 0.0823
Schistosoma mansoni inositol transporter 0.0037 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0077 0.0168 0.0587
Leishmania major cathepsin L-like protease 0.0269 0.0942 0.9442
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0269 0.0942 0.4842
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0519 0.1946 0.6823
Toxoplasma gondii histone deacetylase HDAC5 0.0049 0.0058 0.0577
Schistosoma mansoni alpha-glucosidase 0.0136 0.0407 0.0749
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0077 0.0168 0.0308
Entamoeba histolytica cysteine protease, putative 0.0123 0.0353 0.3736
Mycobacterium ulcerans dehydrogenase 0.0056 0.0084 0.0366
Leishmania major histone deacetylase, putative 0.0078 0.0172 0.1728
Echinococcus multilocularis histone deacetylase 7 0.0078 0.0172 0.0172
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0405 0.1487 0.5215
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0269 0.0942 0.9442
Onchocerca volvulus 0.0269 0.0942 0.7668
Schistosoma mansoni sodium/solute symporter 0.0037 0.0011 0.002
Trypanosoma cruzi prolyl endopeptidase 0.0136 0.0404 0.1418
Echinococcus multilocularis histone deacetylase 8 0.0049 0.0058 0.0058
Leishmania major histone deacetylase, putative 0.0078 0.0172 0.1728
Brugia malayi GH02984p 0.034 0.1225 0.4295
Brugia malayi Integrin alpha pat-2 precursor 0.0148 0.0453 0.159
Plasmodium falciparum cysteine proteinase falcipain 3 0.0269 0.0942 1
Schistosoma mansoni hypothetical protein 0.0128 0.0375 0.069
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0089 0.0892
Plasmodium vivax unspecified product 0.0046 0.0045 0.0481
Brugia malayi Hemopexin family protein 0.0061 0.0107 0.0374
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0053 0.0072 0.0345
Brugia malayi cathepsin L-like cysteine proteinase 0.0077 0.0168 0.0587
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0102 0.1022
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0077 0.0168 0.0308
Trichomonas vaginalis histone deacetylase, putative 0.0095 0.0243 0.1249
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0077 0.0168 0.1778
Echinococcus multilocularis histone deacetylase 6 0.0084 0.0198 0.0198
Trypanosoma brucei histone deacetylase 1 0.0095 0.0243 0.2436
Entamoeba histolytica cysteine proteinase 2 0.0123 0.0353 0.3736
Leishmania major cathepsin L-like protease 0.0269 0.0942 0.9442
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.005 0.0176
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0405 0.1487 0.5215
Loa Loa (eye worm) hypothetical protein 0.0053 0.0072 0.0252
Trypanosoma cruzi cruzipain precursor, putative 0.0269 0.0942 0.3303
Loa Loa (eye worm) hypothetical protein 0.0077 0.0168 0.0587
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0089 0.0457
Echinococcus granulosus histone deacetylase 6 0.0078 0.0172 0.0317
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0077 0.0168 0.0861
Loa Loa (eye worm) hypothetical protein 0.0036 0.0006 0.0023
Giardia lamblia Cathepsin B precursor 0.0283 0.0998 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.0293 0.8585
Onchocerca volvulus 0.0043 0.0034 0.0277
Plasmodium falciparum serine repeat antigen 1 0.0077 0.0168 0.1778
Brugia malayi Papain family cysteine protease containing protein 0.0123 0.0353 0.1237
Echinococcus granulosus polycomb protein SCMH1 0.0097 0.0252 0.0463
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0077 0.0168 0.1768
Plasmodium falciparum histone deacetylase, putative 0.0078 0.0172 0.183
Schistosoma mansoni ap endonuclease 0.0057 0.0089 0.0164
Echinococcus granulosus histone deacetylase 3 0.0095 0.0243 0.0447
Plasmodium falciparum serine repeat antigen 4 0.0077 0.0168 0.1778
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0025 0.0127
Schistosoma mansoni histone deacetylase 0.0095 0.0243 0.0447
Brugia malayi Matrixin family protein 0.0043 0.0034 0.0119
Echinococcus multilocularis geminin 0.1388 0.5434 0.5434
Mycobacterium ulcerans oxidoreductase 0.0056 0.0084 0.0366
Trypanosoma cruzi cysteine peptidase, putative 0.0269 0.0942 0.3303
Brugia malayi Histone deacetylase family protein 0.0078 0.0172 0.0604
Trichomonas vaginalis glucosylceramidase, putative 0.0341 0.1228 0.6314
Echinococcus granulosus lysine specific histone demethylase 1A 0.0056 0.0084 0.0155
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0269 0.0942 0.4842
Loa Loa (eye worm) hypothetical protein 0.0097 0.0252 0.0883
Trypanosoma brucei glucosidase, putative 0.0035 0.0001 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0269 0.0942 0.4842
Schistosoma mansoni histone deacetylase 4 5 0.0078 0.0172 0.0317
Leishmania major hypothetical protein, conserved 0.0101 0.0267 0.2677
Echinococcus granulosus prolyl endopeptidase 0.0136 0.0404 0.0744
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0077 0.0168 0.0861
Giardia lamblia Cathepsin L precursor 0.0077 0.0168 0.1679
Echinococcus multilocularis cathepsin L cysteine protease 0.0269 0.0942 0.0942
Mycobacterium tuberculosis Possible oxidoreductase 0.0056 0.0084 0.0406
Trypanosoma brucei prolyl endopeptidase 0.0136 0.0404 0.4054
Schistosoma mansoni cathepsin S (C01 family) 0.0077 0.0168 0.0308
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0112 0.0309 0.1083
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0159 0.1687
Loa Loa (eye worm) hypothetical protein 0.0101 0.0267 0.0937
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0089 0.0164
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0136 0.0404 0.0744
Plasmodium falciparum serine repeat antigen 2 0.0077 0.0168 0.1778
Plasmodium falciparum serine repeat antigen 9 0.0077 0.0168 0.1778
Onchocerca volvulus 0.0269 0.0942 0.7668
Echinococcus granulosus TRP transient receptor potential channel 0.0036 0.0006 0.0012
Brugia malayi Matrixin family protein 0.0043 0.0034 0.0119
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0111 0.0306 0.1073
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0496 0.0496
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0077 0.0168 0.0308
Loa Loa (eye worm) hypothetical protein 0.0043 0.0034 0.0119
Loa Loa (eye worm) hypothetical protein 0.0056 0.0084 0.0296
Schistosoma mansoni cathepsin F (C01 family) 0.0223 0.0757 0.1393
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0043 0.0034 0.0063
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0159 0.0764
Trypanosoma cruzi histone deacetylase, putative 0.0078 0.0172 0.0604
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0077 0.0168 0.1778
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0077 0.0168 0.0587
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0077 0.0168 0.0861
Echinococcus multilocularis cathepsin L cysteine protease 0.0269 0.0942 0.0942
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0269 0.0942 0.4842
Brugia malayi Matrixin family protein 0.0043 0.0034 0.0119
Loa Loa (eye worm) hypothetical protein 0.0043 0.0034 0.0119
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0745 0.2852 0.5248
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.034 0.1225 0.4295
Loa Loa (eye worm) hypothetical protein 0.0074 0.0159 0.0557
Brugia malayi Thioredoxin reductase 0.0047 0.005 0.0176
Trichomonas vaginalis glucosylceramidase, putative 0.0519 0.1946 1
Trichomonas vaginalis histone deacetylase, putative 0.0095 0.0243 0.1249
Echinococcus granulosus histone deacetylase 6 0.0078 0.0172 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0077 0.0168 0.0861
Brugia malayi histone deacetylase 3 (HD3) 0.0095 0.0243 0.0852
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0123 0.0353 0.3535
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0269 0.0942 0.9442
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0054 0.0077 0.2243
Echinococcus multilocularis histone deacetylase 6 0.0078 0.0172 0.0172
Loa Loa (eye worm) matrixin family protein 0.0105 0.028 0.0983
Trypanosoma brucei histone deacetylase, putative 0.0078 0.0172 0.1728
Toxoplasma gondii histone deacetylase HDAC3 0.0095 0.0243 0.2436
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0269 0.0942 0.9442
Trypanosoma cruzi UDP-galactopyranose mutase 0.0056 0.0084 0.0296
Leishmania major trypanothione reductase 0.0047 0.005 0.0502
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0159 0.0764
Trypanosoma brucei histone deacetylase 3 0.0078 0.0172 0.1728
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0136 0.0404 0.1418
Giardia lamblia Cathepsin B precursor 0.0077 0.0168 0.1679
Loa Loa (eye worm) hypothetical protein 0.0074 0.0159 0.0557
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0046 0.0045 0.0159
Echinococcus granulosus cathepsin l cysteine peptidase 0.0269 0.0942 0.1734

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 31.7 % Inhibition of COX2 at 10 uM ChEMBL. 18412396

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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