Detailed information for compound 1034084

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 231.719 | Formula: C11H18ClNO2
  • H donors: 2 H acceptors: 1 LogP: 3.09 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCc1cc(OC)c(c(c1)CN)O.Cl
  • InChi: 1S/C11H17NO2.ClH/c1-3-4-8-5-9(7-12)11(13)10(6-8)14-2;/h5-6,13H,3-4,7,12H2,1-2H3;1H
  • InChiKey: SYONAIJMNXHHEI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0048
Echinococcus granulosus receptor type guanylyl cyclase 0.0012 0.0027 0.0028
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0218 0.0239
Onchocerca volvulus 0.0053 0.0498 0.0874
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0157 0.028
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.3324 0.5927
Schistosoma mansoni tar DNA-binding protein 0.0135 0.1426 0.1619
Schistosoma mansoni hypothetical protein 0.0022 0.0151 0.0171
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0133 0.0148
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0022 0.0151 0.0169
Echinococcus multilocularis ring and YY1 binding protein 0.018 0.1928 0.1926
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0008 0.0007
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0008 0.0015
Echinococcus granulosus metabotropic glutamate receptor 5 0.0012 0.0027 0.0028
Echinococcus granulosus GPCR family 2 0.0014 0.0052 0.0057
Brugia malayi YY1-associated factor 2 0.018 0.1928 0.3438
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0015
Brugia malayi tailless protein 0.001 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0015
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0058 0.0548 0.2846
Trichomonas vaginalis conserved hypothetical protein 0.0505 0.5607 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0048
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0134 0.0132
Echinococcus granulosus glutamate receptor subunit protein glur 0.0022 0.0151 0.0169
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0034 0.0281 0.0279
Brugia malayi Kinesin motor domain containing protein 0.0025 0.0174 0.031
Brugia malayi nuclear receptor NHR-88 0.001 0.0008 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0135 0.1426 0.1619
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0048
Schistosoma mansoni microtubule-associated protein tau 0.0788 0.8807 1
Echinococcus granulosus kinesin family 1 0.0189 0.203 0.2303
Echinococcus granulosus metabotropic glutamate receptor 2 0.0012 0.0027 0.0028
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0008 0.0007
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0134 0.0238
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0008 0.0015
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.018 0.1928 0.4792
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0008 0.0015
Echinococcus multilocularis tumor protein p63 0.0329 0.3613 0.3612
Onchocerca volvulus 0.0012 0.0027 0.0033
Brugia malayi Receptor family ligand binding region containing protein 0.0012 0.0027 0.0048
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.018 0.1928 0.3438
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0919 0.164
Loa Loa (eye worm) hypothetical protein 0.0319 0.3503 0.6247
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0362 0.3994 0.7124
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0265 0.0472
Chlamydia trachomatis SWIB complex protein 0.0505 0.5607 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0133 0.0237
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0134 0.0152
Loa Loa (eye worm) RiNg Finger protein family member 0.0009 0.0002 0.0004
Brugia malayi brahma associated protein 60 kDa 0.0505 0.5607 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0133 0.0131
Echinococcus multilocularis tar DNA binding protein 0.0135 0.1426 0.1424
Loa Loa (eye worm) TAR-binding protein 0.0135 0.1426 0.2543
Schistosoma mansoni tar DNA-binding protein 0.0135 0.1426 0.1619
Schistosoma mansoni hypothetical protein 0.0014 0.0052 0.0059
Brugia malayi Cytochrome P450 family protein 0.003 0.0238 0.0425
Loa Loa (eye worm) hypothetical protein 0.018 0.1928 0.3438
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0301 0.0341
Echinococcus multilocularis microtubule associated protein 2 0.0788 0.8807 0.8807
Loa Loa (eye worm) histone methyltransferase 0.001 0.0009 0.0016
Echinococcus granulosus ring and YY1 binding protein 0.018 0.1928 0.2187
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.018 0.1928 0.4792
Loa Loa (eye worm) hypothetical protein 0.0043 0.0388 0.0691
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0008 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0134 0.0238
Loa Loa (eye worm) hypothetical protein 0.018 0.1928 0.3438
Loa Loa (eye worm) kinesin-like protein KLP2 0.0025 0.0174 0.031
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0134 0.0238
Schistosoma mansoni hypothetical protein 0.0505 0.5607 0.6366
Schistosoma mansoni glutamate receptor AMPA 0.0022 0.0151 0.0171
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0007 0.0013
Schistosoma mansoni hypothetical protein 0.0505 0.5607 0.6366
Loa Loa (eye worm) acetyltransferase 0.0126 0.1324 0.2361
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0134 0.0152
Brugia malayi latrophilin 2 splice variant baaae 0.003 0.0232 0.0414
Entamoeba histolytica kinesin, putative 0.0025 0.0174 0.1191
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.126 1
Trypanosoma cruzi WLM domain containing protein, putative 0.018 0.1928 0.4792
Brugia malayi 6-phosphofructokinase 0.0121 0.126 0.2247
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0012 0.0027 0.0025
Brugia malayi Muscleblind-like protein 0.0319 0.3503 0.6247
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0121 0.126 1
Schistosoma mansoni tyrosine kinase 0.0012 0.0027 0.0031
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0022 0.002
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0441 0.05
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0034 0.0281 0.0279
Onchocerca volvulus 0.0048 0.0441 0.0772
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0134 0.0132
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0022 0.0151 0.0149
Echinococcus granulosus survival motor neuron protein 1 0.0261 0.2843 0.3226
Leishmania major hypothetical protein, conserved 0.018 0.1928 0.4827
Echinococcus granulosus glutamate receptor 2 0.0034 0.0281 0.0317
Schistosoma mansoni 6-phosphofructokinase 0.0121 0.126 0.143
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0505 0.5607 1
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0008 0.0015
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0008 0.0006
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0134 0.0238
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0919 0.1044
Onchocerca volvulus 0.0021 0.0134 0.0224
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0008 0.0015
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0505 0.5607 1
Schistosoma mansoni brg-1 associated factor 0.0505 0.5607 0.6366
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0157 0.028
Schistosoma mansoni hypothetical protein 0.0014 0.0052 0.0059
Echinococcus multilocularis glutamate receptor 2 0.0034 0.0281 0.0279
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0555 0.0784
Trichomonas vaginalis ran, putative 0.0021 0.0133 0.0237
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0012 0.0027 0.0048
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0034 0.0281 0.0317
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0048
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.008 0.0802 0.08
Schistosoma mansoni hypothetical protein 0.0406 0.4489 0.5097
Schistosoma mansoni tar DNA-binding protein 0.0135 0.1426 0.1619
Entamoeba histolytica hypothetical protein 0.0036 0.0301 0.222
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0239 0.0207
Schistosoma mansoni hypothetical protein 0.002 0.0125 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0134 0.0238
Echinococcus multilocularis zinc finger protein Ran binding 0.018 0.1928 0.1926
Schistosoma mansoni survival motor neuron protein 0.0053 0.0498 0.0565
Loa Loa (eye worm) 6-phosphofructokinase 0.0121 0.126 0.2247
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0134 0.0149
Trypanosoma brucei cytochrome P450, putative 0.003 0.0238 0.0292
Schistosoma mansoni hypothetical protein 0.003 0.0232 0.0264
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0133 0.0237
Echinococcus multilocularis nmda type glutamate receptor 0.008 0.0802 0.08
Loa Loa (eye worm) hypothetical protein 0.0021 0.0134 0.0238
Entamoeba histolytica Ran family GTPase 0.0021 0.0133 0.086
Echinococcus multilocularis muscleblind protein 1 0.0319 0.3503 0.3501
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0012 0.0027 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0134 0.0238
Echinococcus granulosus geminin 0.0188 0.2022 0.2293
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.018 0.1928 0.3438
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0015
Schistosoma mansoni nuclear hormone receptor 0.001 0.0008 0.001
Loa Loa (eye worm) cytochrome P450 0.002 0.0125 0.0223
Brugia malayi nuclear hormone receptor 0.0021 0.0134 0.0238
Onchocerca volvulus 0.003 0.0239 0.0411
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0239 0.0271
Schistosoma mansoni glutamate receptor kainate 0.0022 0.0151 0.0171
Loa Loa (eye worm) RGC/RGC protein kinase 0.0012 0.0027 0.0048
Echinococcus multilocularis cpg binding protein 0.003 0.0237 0.0235
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0009 0.0007
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.018 0.1928 0.3438
Echinococcus granulosus snurportin 1 0.0303 0.3324 0.3772
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0265 0.193
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0134 0.0224
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.224 0.3995
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0133 0.4723
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0265 0.0472
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0022 0.0022
Echinococcus multilocularis kinesin family 1 0.0189 0.203 0.2028
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0134 0.0238
Onchocerca volvulus 0.0505 0.5607 1
Plasmodium vivax SET domain protein, putative 0.003 0.0239 0.0194
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0012 0.0027 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0134 0.0238
Schistosoma mansoni hypothetical protein 0.0014 0.0052 0.0059
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0008 0.001
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0505 0.5607 1
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0008 0.0006
Schistosoma mansoni glutamate receptor AMPA 0.0022 0.0151 0.0171
Schistosoma mansoni cpg binding protein 0.0029 0.0219 0.0249
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0919 0.164
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0121 0.126 0.2932
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0126 0.1324 0.1503
Loa Loa (eye worm) hypothetical protein 0.001 0.001 0.0017
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.126 0.2247
Leishmania major cytochrome p450-like protein 0.002 0.0125 0.0313
Onchocerca volvulus 0.018 0.1928 0.3429
Loa Loa (eye worm) hypothetical protein 0.0185 0.1991 0.3551
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0008 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0134 0.0238
Trypanosoma brucei C-8 sterol isomerase, putative 0.0362 0.3994 1
Brugia malayi nuclear receptor NHR-67 0.001 0.0008 0.0015
Entamoeba histolytica hypothetical protein 0.0036 0.0301 0.222
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0505 0.5607 0.6365
Schistosoma mansoni zinc finger protein 0.001 0.0008 0.001
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0265 0.0255
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.018 0.1928 0.3289
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0034 0.0281 0.0317
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0134 0.0238
Echinococcus multilocularis GPCR, family 2 0.0014 0.0052 0.005
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0134 0.0152
Loa Loa (eye worm) glutamate receptor 0.0012 0.0027 0.0048
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0012 0.0027 0.0025
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0015
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0037 0.0316 0.0349
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0022 0.0151 0.0169
Brugia malayi hypothetical protein 0.001 0.0008 0.0015
Echinococcus granulosus importin subunit beta 1 0.0028 0.0218 0.0245
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.126 1
Echinococcus multilocularis NMDA receptor 0.0022 0.0151 0.0149
Brugia malayi SWIB/MDM2 domain containing protein 0.0505 0.5607 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0009 0.0007
Onchocerca volvulus 0.018 0.1928 0.3429
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.018 0.1928 0.3279
Loa Loa (eye worm) hypothetical protein 0.003 0.0232 0.0414
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0218 0.0215
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.126 1
Schistosoma mansoni hypothetical protein 0.0164 0.1753 0.199
Loa Loa (eye worm) hypothetical protein 0.0048 0.0441 0.0786
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.018 0.1928 0.1926
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0265 0.0241
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0134 0.0238
Schistosoma mansoni importin beta-1 0.0028 0.0218 0.0247
Leishmania major cytochrome p450-like protein 0.002 0.0125 0.0313
Leishmania major extracellular receptor, putative 0.0012 0.0027 0.0067
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0039
Loa Loa (eye worm) hypothetical protein 0.0021 0.0134 0.0238
Echinococcus granulosus histone acetyltransferase KAT2B 0.0123 0.1284 0.1456
Brugia malayi Cytochrome P450 family protein 0.002 0.0125 0.0223
Trichomonas vaginalis set domain proteins, putative 0.0236 0.2563 0.4571
Brugia malayi Importin beta-1 subunit 0.0028 0.0218 0.0388
Entamoeba histolytica hypothetical protein 0.0036 0.0301 0.222
Brugia malayi Guanylyl cyclase protein 23 0.0012 0.0027 0.0048
Loa Loa (eye worm) hypothetical protein 0.0028 0.0218 0.0388
Schistosoma mansoni nuclear receptor 0.001 0.0008 0.001
Giardia lamblia Kinesin-5 0.0025 0.0174 0.6175
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0022 0.0151 0.0149
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0134 0.0152
Schistosoma mansoni cpg binding protein 0.003 0.0237 0.027
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0134 0.0152
Trypanosoma cruzi WLM domain containing protein, putative 0.018 0.1928 0.4792
Echinococcus granulosus Zinc finger RanBP2 type 0.018 0.1928 0.2187
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0301 0.0298
Schistosoma mansoni fusion 0.018 0.1928 0.2189
Brugia malayi TAR-binding protein 0.0135 0.1426 0.2543
Echinococcus granulosus dnaJ subfamily B 0.0406 0.4489 0.5095
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0008 0.0007
Brugia malayi Nuclear hormone receptor E75 0.001 0.0008 0.0015
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0037 0.0316 0.0349
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0134 0.0238
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0058 0.0548 0.2846
Schistosoma mansoni hypothetical protein 0.0188 0.2022 0.2295
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0039
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0133 0.0014
Schistosoma mansoni hypothetical protein 0.018 0.1928 0.2189
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0134 0.0132
Brugia malayi RNA recognition motif domain containing protein 0.0135 0.1426 0.2543
Echinococcus multilocularis glutamate receptor 2 0.0022 0.0151 0.0149
Loa Loa (eye worm) RGC/RGC protein kinase 0.0012 0.0027 0.0048
Schistosoma mansoni tar DNA-binding protein 0.0135 0.1426 0.1619
Loa Loa (eye worm) hypothetical protein 0.0362 0.3994 0.7124
Mycobacterium ulcerans 6-phosphofructokinase 0.0121 0.126 1
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0134 0.0132
Loa Loa (eye worm) CYP4Cod1 0.003 0.0238 0.0425
Echinococcus granulosus glutamate receptor 2 0.0012 0.0027 0.0028
Schistosoma mansoni ran 0.0021 0.0133 0.0151
Brugia malayi Latrophilin receptor protein 2 0.0014 0.0052 0.0093
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0134 0.0238
Loa Loa (eye worm) hypothetical protein 0.018 0.1928 0.3438
Schistosoma mansoni cytochrome P450 0.002 0.0125 0.0142
Leishmania major cytochrome p450-like protein 0.003 0.0238 0.0596
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.018 0.1928 0.3438
Schistosoma mansoni glutamate receptor NMDA 0.0022 0.0151 0.0171
Loa Loa (eye worm) hypothetical protein 0.0021 0.0134 0.0238
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0012 0.0027 0.0048
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.018 0.1928 0.4659
Schistosoma mansoni nuclear receptor 0.001 0.0008 0.001
Leishmania major hypothetical protein, conserved 0.018 0.1928 0.4827
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0134 0.0132
Loa Loa (eye worm) hypothetical protein 0.0021 0.0134 0.0238
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0134 0.0149
Schistosoma mansoni metabotropic glutamate receptor 0.0012 0.0027 0.0031
Loa Loa (eye worm) hypothetical protein 0.0021 0.0134 0.0238
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.126 0.2247
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0014 0.0052 0.0057
Brugia malayi RNA binding protein 0.0135 0.1426 0.2543
Brugia malayi hypothetical protein 0.0012 0.0027 0.0048
Leishmania major importin beta-1 subunit, putative 0.0023 0.0157 0.0393
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0134 0.0238
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0134 0.0132
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0022 0.0151 0.0169
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0134 0.0238
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0134 0.0152
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0265 0.0255
Echinococcus multilocularis SWI:SNF matrix associated 0.0505 0.5607 0.5606
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0239 0.0271
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0219 0.0247
Schistosoma mansoni glutamate receptor NMDA 0.0034 0.0281 0.0319
Brugia malayi Glutamate receptor 2 precursor 0.0022 0.0151 0.0269
Echinococcus granulosus nmda type glutamate receptor 0.0012 0.0027 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0134 0.0238
Schistosoma mansoni tyrosine kinase 0.0012 0.0027 0.0031
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0505 0.5607 0.5606
Loa Loa (eye worm) hypothetical protein 0.0021 0.0134 0.0238
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0022 0.0025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0919 0.1042
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0219 0.0391
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0134 0.0152
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0014 0.0052 0.0057
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0238 0.0533
Loa Loa (eye worm) glutamate receptor 1 0.0022 0.0151 0.0269
Toxoplasma gondii kinesin motor domain-containing protein 0.0025 0.0174 0.0089
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0265 0.0472
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0014 0.0052 0.005
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0239 0.0237
Loa Loa (eye worm) latrophilin receptor protein 2 0.0014 0.0052 0.0093
Loa Loa (eye worm) hypothetical protein 0.0261 0.2843 0.507
Brugia malayi Cytochrome P450 family protein 0.0064 0.0618 0.1102
Entamoeba histolytica hypothetical protein 0.0036 0.0301 0.222
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0015
Echinococcus granulosus tumor protein p63 0.0329 0.3613 0.4101
Trypanosoma brucei hypothetical protein, conserved 0.018 0.1928 0.4659
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0919 0.0917
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0919 0.1044
Loa Loa (eye worm) hypothetical protein 0.0319 0.3503 0.6247
Leishmania major lanosterol 14-alpha-demethylase, putative 0.002 0.0125 0.0313
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0265 0.9414
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0134 0.0238
Brugia malayi hypothetical protein 0.0011 0.0022 0.0039
Loa Loa (eye worm) RGC/RGC protein kinase 0.0012 0.0027 0.0048
Schistosoma mansoni hypothetical protein 0.0188 0.2022 0.2295
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0008 0.0015
Echinococcus granulosus tar DNA binding protein 0.0135 0.1426 0.1617
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0008 0.0006
Loa Loa (eye worm) brahma associated protein 0.0505 0.5607 1
Echinococcus granulosus glutamate NMDA receptor subunit 0.0022 0.0151 0.0169
Schistosoma mansoni hypothetical protein 0.0036 0.0301 0.0341
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0008 0.001
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0134 0.0132
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.018 0.1928 0.4659
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0134 0.0149
Brugia malayi phosphofructokinase 0.0121 0.126 0.2247
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0238 0.0425
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0919 0.0917
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0265 0.0472
Schistosoma mansoni nuclear hormone receptor 0.001 0.0008 0.001
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0134 0.0152
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0134 0.0224
Schistosoma mansoni ATP-binding cassette transporter 0.0022 0.0151 0.0171
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0134 0.0149
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0134 0.0238
Trichomonas vaginalis cell cycle control protein cwf24, putative 0.0009 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0048
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0014 0.0052 0.005
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0034 0.0281 0.0279
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0134 0.0238
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0618 0.1102
Onchocerca volvulus 0.0316 0.3474 0.619
Trypanosoma cruzi hypothetical protein, conserved 0.018 0.1928 0.4792
Schistosoma mansoni cpg binding protein 0.003 0.0237 0.027
Brugia malayi nuclear receptor RXR 0.0011 0.0022 0.0039
Schistosoma mansoni 6-phosphofructokinase 0.0121 0.126 0.143
Leishmania major ATP-dependent phosphofructokinase 0.0121 0.126 0.3154
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0265 0.0241
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0239 0.0237
Trypanosoma cruzi hypothetical protein, conserved 0.018 0.1928 0.4792
Leishmania major hypothetical protein, conserved 0.018 0.1928 0.4827
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0015
Brugia malayi Calcitonin receptor-like protein seb-1 0.0043 0.0388 0.0691
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0121 0.126 1
Onchocerca volvulus 0.0012 0.0027 0.0033
Echinococcus granulosus Nuclear pore complex protein Nup153 0.018 0.1928 0.2187
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0058 0.0548 0.053
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0505 0.5607 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0125 0.0248
Brugia malayi ecdysteroid receptor 0.0021 0.0134 0.0238
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0919 0.1042
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0133 0.002
Plasmodium vivax kinesin-5 0.0025 0.0174 0.0075
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0039
Echinococcus granulosus tyrosine kinase 0.0012 0.0027 0.0028
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0043 0.0388 0.0691
Plasmodium vivax importin-beta 2, putative 0.0028 0.0218 0.0155
Echinococcus granulosus microtubule associated protein 2 0.0788 0.8807 1
Brugia malayi Glutamate receptor 1 precursor 0.0022 0.0151 0.0269
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0498 0.0887
Brugia malayi nuclear receptor NHR-88 0.0021 0.0134 0.0238
Toxoplasma gondii ran binding protein 0.018 0.1928 0.3289
Brugia malayi steroid hormone receptor 0.0021 0.0134 0.0238
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0058 0.0548 0.3727
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0037 0.0316 0.0335
Schistosoma mansoni protein kinase 0.0012 0.0027 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0134 0.0238
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0008 0.0007
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0022 0.0025
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0239 0.0269
Echinococcus multilocularis 0.002 0.0125 0.0123
Plasmodium falciparum kinesin-5 0.0025 0.0174 0.0075
Echinococcus granulosus histone acetyltransferase KAT2B 0.0037 0.0316 0.0357
Chlamydia trachomatis glutamine binding protein 0.0058 0.0548 0.053
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0218 0.0169
Echinococcus granulosus cytochrome P450 2K1 0.002 0.0125 0.014
Brugia malayi conserved hypotetical protein 0.001 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0316 0.3474 0.6195
Schistosoma mansoni hypothetical protein 0.0014 0.0052 0.0059
Echinococcus multilocularis 6 phosphofructokinase 0.0121 0.126 0.1258
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0037 0.0316 0.0564
Entamoeba histolytica hypothetical protein 0.0023 0.0157 0.1055
Leishmania major C-8 sterol isomerase-like protein 0.0362 0.3994 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0134 0.0238
Brugia malayi Zinc finger protein 183 homolog 0.0009 0.0002 0.0004
Loa Loa (eye worm) DR-78 0.001 0.0008 0.0015
Brugia malayi Receptor family ligand binding region containing protein 0.0012 0.0027 0.0048
Onchocerca volvulus 0.018 0.1928 0.3429
Brugia malayi RNA, U transporter 1 0.0081 0.0809 0.1444
Chlamydia trachomatis DNA topoisomerase I 0.0505 0.5607 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0012 0.0027 0.0033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0919 0.1044
Onchocerca volvulus 0.0236 0.2563 0.4563
Echinococcus granulosus nmda type glutamate receptor 0.008 0.0802 0.0908
Brugia malayi Cytochrome P450 family protein 0.003 0.0238 0.0425
Giardia lamblia Histone acetyltransferase GCN5 0.0034 0.0281 1
Brugia malayi Nuclear hormone receptor E75 0.001 0.0008 0.0015
Echinococcus multilocularis muscleblind protein 0.0319 0.3503 0.3501
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.018 0.1928 0.4792
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.0093
Trypanosoma cruzi hypothetical protein, conserved 0.018 0.1928 0.4792
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0008 0.0006
Echinococcus multilocularis dnaJ subfamily B 0.0406 0.4489 0.4487
Loa Loa (eye worm) hypothetical protein 0.018 0.1928 0.3438
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0008 0.0007
Trichomonas vaginalis bromodomain-containing protein, putative 0.0037 0.0316 0.0564
Echinococcus multilocularis geminin 0.0188 0.2022 0.202
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0134 0.0149
Schistosoma mansoni hypothetical protein 0.0009 0.0002 0.0003
Echinococcus multilocularis tyrosine kinase 0.0012 0.0027 0.0025
Loa Loa (eye worm) RNA binding protein 0.0135 0.1426 0.2543
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0426
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0157 0.028
Brugia malayi Metabotropic glutamate receptor precursor. 0.0012 0.0027 0.0048
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0265 0.0255
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0134 0.0238
Brugia malayi Pre-SET motif family protein 0.0207 0.224 0.3995
Entamoeba histolytica acetyltransferase, GNAT family 0.0034 0.0281 0.2064
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0121 0.126 0.3107
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0125 0.0248
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0265 0.0472
Plasmodium vivax hypothetical protein, conserved 0.0505 0.5607 1
Echinococcus multilocularis SWI:SNF matrix associated 0.0505 0.5607 0.5606
Echinococcus multilocularis survival motor neuron protein 1 0.0261 0.2843 0.2841
Echinococcus granulosus atrial natriuretic peptide receptor 0.0012 0.0027 0.0028
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0134 0.0132
Schistosoma mansoni glutamate receptor kainate 0.0022 0.0151 0.0171
Echinococcus multilocularis snurportin 1 0.0303 0.3324 0.3322
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0022 0.0039
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0265 0.0241
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0134 0.0132
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0008 0.0006
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.018 0.1928 0.4792
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0039
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0265 0.0472
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0593 0.0673
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0134 0.0149
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0134 0.0152
Brugia malayi brahma associated protein 60 kDa 0.0505 0.5607 1
Brugia malayi nuclear hormone receptor 0.001 0.0008 0.0015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0134 0.0149
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0134 0.0152
Echinococcus multilocularis glutamate receptor 2 0.0012 0.0027 0.0025
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0048
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0265 0.0472
Schistosoma mansoni metabotropic glutamate receptor 0.0012 0.0027 0.0031
Brugia malayi Pre-SET motif family protein 0.003 0.0239 0.0426
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0022 0.0039
Schistosoma mansoni hypothetical protein 0.0053 0.0498 0.0565
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0034 0.0281 0.0317
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0134 0.0152
Echinococcus multilocularis receptor type guanylyl cyclase 0.0012 0.0027 0.0025
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0015
Brugia malayi metabotropic glutamate receptor type 2 0.0012 0.0027 0.0048
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0157 0.0328
Trypanosoma cruzi cytochrome p450-like protein, putative 0.002 0.0125 0.0248
Echinococcus multilocularis Zinc finger, RanBP2 type 0.018 0.1928 0.1926
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0134 0.0238
Leishmania major GTP-binding protein, putative 0.0021 0.0133 0.0333
Echinococcus multilocularis SWI:SNF matrix associated 0.0505 0.5607 0.5606
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0301 0.0339
Echinococcus granulosus zinc finger protein Ran binding 0.018 0.1928 0.2187
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0058 0.0548 0.3727
Loa Loa (eye worm) hypothetical protein 0.018 0.1928 0.3438
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0048
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0133 0.0267
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0239 0.0271
Brugia malayi hypothetical protein 0.001 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0134 0.0238
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0126 0.1324 0.1322
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0022 0.0151 0.0149
Brugia malayi hypothetical protein 0.0036 0.0301 0.0536
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0238 0.0425
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0362 0.3994 1
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0034 0.0281 0.0279
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0015
Echinococcus granulosus cpg binding protein 0.003 0.0237 0.0267
Brugia malayi 6-phosphofructokinase 0.0121 0.126 0.2247
Schistosoma mansoni glutamate receptor kainate 0.0022 0.0151 0.0171
Brugia malayi nuclear receptor RXR 0.001 0.0008 0.0015
Echinococcus granulosus SWI:SNF matrix associated 0.0505 0.5607 0.6365
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0121 0.126 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.003 0.0238 0.0997
Leishmania major hypothetical protein, conserved 0.018 0.1928 0.4827
Schistosoma mansoni hypothetical protein 0.0505 0.5607 0.6366
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.126 0.2247
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0134 0.0149
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0133 0.0267
Echinococcus granulosus 6 phosphofructokinase 0.0121 0.126 0.1428
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0265 0.0241
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.126 0.2247
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0022 0.0151 0.0149
Schistosoma mansoni coup transcription factor 0.0021 0.0134 0.0152
Brugia malayi hypothetical protein 0.0011 0.0022 0.0039
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0015
Brugia malayi ecdysone receptor 0.001 0.0008 0.0015
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0034 0.0281 0.0317
Schistosoma mansoni TRABID protein (C64 family) 0.018 0.1928 0.2189
Brugia malayi cytochrome P450 0.002 0.0125 0.0223
Echinococcus granulosus muscleblind protein 0.0319 0.3503 0.3975
Onchocerca volvulus 0.0029 0.0219 0.0376
Loa Loa (eye worm) 6-phosphofructokinase 0.0121 0.126 0.2247
Schistosoma mansoni RNA binding protein 0.018 0.1928 0.2189
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0012 0.0027 0.0048
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.018 0.1928 0.4792
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0134 0.0152
Brugia malayi CXXC zinc finger family protein 0.0029 0.0219 0.0391
Trypanosoma brucei hypothetical protein, conserved 0.018 0.1928 0.4659
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0134 0.0224
Plasmodium falciparum importin beta, putative 0.0028 0.0218 0.0155
Onchocerca volvulus 0.018 0.1928 0.3429
Schistosoma mansoni hypothetical protein 0.0303 0.3324 0.3774
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0039
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0238 0.0533
Schistosoma mansoni zinc finger protein 0.018 0.1928 0.2189
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0014 0.0052 0.0093
Plasmodium falciparum histone acetyltransferase GCN5 0.0034 0.0281 0.0271
Echinococcus multilocularis nmda type glutamate receptor 0.0012 0.0027 0.0025
Loa Loa (eye worm) glutamate receptor 2 0.0022 0.0151 0.0269
Brugia malayi hypothetical protein 0.0316 0.3474 0.6195
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0134 0.0238
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0022 0.0039
Schistosoma mansoni kinesin eg-5 0.0025 0.0174 0.0197
Brugia malayi hypothetical protein 0.0261 0.2843 0.507
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.018 0.1928 0.3429
Leishmania major hypothetical protein, conserved 0.018 0.1928 0.4827
Loa Loa (eye worm) phosphofructokinase 0.0121 0.126 0.2247
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0043 0.0388 0.0691
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0239 0.0271
Schistosoma mansoni ran 0.0021 0.0133 0.0151
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0218 0.0239
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0505 0.5607 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0134 0.0149
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0134 0.0238
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0505 0.5607 1
Brugia malayi acetyltransferase, GNAT family protein 0.0126 0.1324 0.2361
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0048
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0135 0.1426 0.2543

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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