Detailed information for compound 1035412

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 331.823 | Formula: C15H14ClN5S
  • H donors: 2 H acceptors: 2 LogP: 3.48 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC(=N)Nc1nnc(s1)c1ccccc1c1ccccc1.Cl
  • InChi: 1S/C15H13N5S.ClH/c16-14(17)18-15-20-19-13(21-15)12-9-5-4-8-11(12)10-6-2-1-3-7-10;/h1-9H,(H4,16,17,18,20);1H
  • InChiKey: XIVPCHUMWSPCHH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0007 0.0036
Toxoplasma gondii exonuclease III APE 0.0067 0.0343 0.6955
Plasmodium falciparum phenylalanine--tRNA ligase alpha subunit 0.009 0.0493 1
Entamoeba histolytica phenylalanyl-tRNA synthetase alpha subunit, putative 0.009 0.0493 1
Mycobacterium tuberculosis Conserved protein 0.0046 0.0211 0.0787
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0013 0.0001 0.0004
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0211 0.4273
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0046 0.0209 0.0781
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0013 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0038
Mycobacterium ulcerans esterase/lipase LipP 0.0046 0.0211 0.0786
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0046 0.0211 0.0211
Schistosoma mansoni phenylalanyl-tRNA synthetase mitochondrial 0.0026 0.0081 0.0081
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0013 0 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0005 0.0097
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0067 0.0343 0.6955
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0202 0.4086
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0027 0.009 0.0487
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0344 0.6979
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0067 0.0343 0.0343
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0233 0.4722
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0046 0.0209 0.0781
Schistosoma mansoni chromobox protein 0.0067 0.0344 0.0344
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0034 0.0135 0.0502
Brugia malayi Smad1 0.002 0.0045 0.0244
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0211 0.4273
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0255 0.5172
Echinococcus granulosus chromobox protein 1 0.0067 0.0344 0.0344
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0027 0.009 0.009
Schistosoma mansoni apoferritin-2 0.002 0.0044 0.0044
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.009 0.0487
Brugia malayi RNA binding protein 0.0082 0.0439 0.2379
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0124 0.0711 0.0711
Brugia malayi Calcitonin receptor-like protein seb-1 0.0259 0.1577 0.8549
Echinococcus multilocularis survival motor neuron protein 1 0.0224 0.1354 0.1354
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0026 0.0081 0.1646
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0067 0.0343 0.6955
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0058 0.1163
Schistosoma mansoni thyroid hormone receptor 0.0027 0.009 0.009
Giardia lamblia Phenylalanyl-tRNA synthetase alpha chain 0.009 0.0493 1
Schistosoma mansoni ferritin light chain 0.002 0.0044 0.0044
Brugia malayi Steroid receptor seven-up type 2 0.0027 0.009 0.0487
Schistosoma mansoni tar DNA-binding protein 0.0082 0.0439 0.0439
Brugia malayi nuclear hormone receptor 0.0027 0.009 0.0487
Loa Loa (eye worm) heterochromatin protein 1 0.0067 0.0344 0.1864
Entamoeba histolytica acyl-coA synthetase, putative 0.0046 0.0209 0.4248
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0032 0.0123 0.0457
Leishmania major acetyl-CoA synthetase, putative 0.0013 0.0001 0.0004
Schistosoma mansoni hypothetical protein 0.0015 0.0014 0.0014
Brugia malayi Heterochromatin protein 1 0.0067 0.0344 0.1862
Loa Loa (eye worm) hypothetical protein 0.0046 0.0211 0.1143
Brugia malayi Bromodomain containing protein 0.0029 0.0099 0.0533
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0027 0.009 0.009
Schistosoma mansoni zinc finger protein 0.0016 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0038
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0013 0.0001 0.0004
Plasmodium vivax phenylalanine--tRNA ligase alpha subunit, putative 0.009 0.0493 1
Brugia malayi RNA recognition motif domain containing protein 0.0082 0.0439 0.2379
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0013 0.0001 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0082 0.0439 0.0439
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.017 0.3448
Loa Loa (eye worm) beta-lactamase 0.0046 0.0211 0.1143
Brugia malayi TAR-binding protein 0.0082 0.0439 0.2379
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0013 0.0001 0.0004
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0027 0.0088 0.0088
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0037 0.0155 0.2096
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0018 0.0033 0.0033
Trichomonas vaginalis antibiotic synthetase, putative 0.0013 0.0001 0.0004
Brugia malayi steroid hormone receptor 0.0027 0.009 0.0487
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.0429 0.2673 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0211 0.1143
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0067 0.0343 0.1856
Loa Loa (eye worm) hypothetical protein 0.0034 0.0135 0.0731
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0023 0.0466
Mycobacterium ulcerans beta-lactamase 0.0046 0.0211 0.0786
Trypanosoma cruzi target of rapamycin kinase 3 0.0053 0.0255 0.5179
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.009 0.0493 0.0493
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0209 0.4248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0255 0.5172
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0013 0 0.0003
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0027 0.009 0.009
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0034 0.0135 0.0731
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0005 0.0097
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0209 0.0782
Brugia malayi CHD4 protein 0.0014 0.0003 0.0016
Schistosoma mansoni cpg binding protein 0.0027 0.0087 0.0087
Brugia malayi phenylalanyl (f) trna synthetase protein 1 0.009 0.0493 0.2669
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0155 0.3139
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0014 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0137 0.0794 0.4308
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0013 0.0001 0.0001
Echinococcus multilocularis phenylalanyl tRNA synthetase alpha chain B 0.009 0.0493 0.0493
Mycobacterium tuberculosis Probable esterase LipL 0.0046 0.0211 0.0787
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0001 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0124 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0004
Echinococcus granulosus ecdysone induced protein 78C 0.0027 0.009 0.009
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0013 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0027 0.009 0.0487
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0027 0.009 0.009
Brugia malayi AMP-binding enzyme family protein 0.0013 0.0001 0.0001
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0067 0.0343 0.128
Echinococcus multilocularis tar DNA binding protein 0.0082 0.0439 0.0439
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0001 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0082 0.0439 0.0439
Loa Loa (eye worm) hypothetical protein 0.009 0.0493 0.267
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0029 0.0579
Echinococcus granulosus beta LACTamase domain containing family member 0.0046 0.0211 0.0211
Schistosoma mansoni bromodomain containing protein 0.0049 0.0229 0.0229
Mycobacterium leprae Probable lipase LipE 0.0046 0.0211 0.6477
Echinococcus multilocularis sterol O acyltransferase 1 0.0137 0.0794 0.0794
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0209 0.1134
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0058 0.1163
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0124 0.0711 0.0711
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0145 0.2939
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0026 0.0081 0.1646
Brugia malayi hypothetical protein 0.0224 0.1354 0.7341
Toxoplasma gondii Ferredoxin-fold anticodon binding domain-containing protein 0.0026 0.0081 0.1646
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0295 0.181 0.677
Brugia malayi MH2 domain containing protein 0.03 0.1844 1
Echinococcus multilocularis tumor protein p63 0.0875 0.554 0.554
Onchocerca volvulus 0.0013 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0027 0.0088 0.0088
Chlamydia trachomatis phenylalanine--tRNA ligase subunit alpha 0.0429 0.2673 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0027 0.009 0.009
Echinococcus granulosus zinc finger protein 0.0016 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0027 0.009 0.0489
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0027 0.009 0.009
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0013 0.0001 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0209 0.0781
Trichomonas vaginalis ferritin, putative 0.002 0.0044 0.0882
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0032 0.0123 0.0457
Echinococcus granulosus expressed protein 0.002 0.0044 0.0044
Echinococcus multilocularis phenylalanyl tRNA synthetase 0.0026 0.0081 0.0081
Brugia malayi chromobox protein homolog 3 0.0037 0.0155 0.0838
Echinococcus multilocularis beta LACTamase domain containing family member 0.0046 0.0211 0.0211
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0173 0.2344
Schistosoma mansoni TGF-beta signal transducer Smad2 0.002 0.0045 0.0045
Echinococcus multilocularis chromobox protein 1 0.0067 0.0344 0.0344
Echinococcus granulosus geminin 0.0358 0.2219 0.2219
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0046 0.0212 0.0212
Mycobacterium tuberculosis Conserved protein 0.0046 0.0211 0.0787
Echinococcus granulosus smad 0.002 0.0045 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0233 0.4722
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0013 0.0001 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0255 0.5172
Loa Loa (eye worm) hypothetical protein 0.0124 0.0708 0.3841
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0124 0.0711 0.0711
Onchocerca volvulus 0.0013 0.0001 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0023 0.0466
Echinococcus multilocularis zinc finger protein 0.0016 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0358 0.2219 0.2219
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0046 0.0211 0.0211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0168 0.3396
Echinococcus granulosus FTZ F1 alpha 0.0027 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0037 0.0155 0.084
Mycobacterium tuberculosis Conserved protein 0.0046 0.0211 0.0787
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.009 0.0487
Loa Loa (eye worm) hypothetical protein 0.0029 0.0099 0.0537
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0013 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0004
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0034 0.0135 0.0502
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0027 0.009 0.0489
Schistosoma mansoni microtubule-associated protein tau 0.1568 1 1
Entamoeba histolytica hypothetical protein 0.0027 0.0088 0.177
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.009 0.0487
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0022 0.0058 0.031
Leishmania major acetyl-CoA synthetase, putative 0.0013 0.0001 0.0004
Brugia malayi MH1 domain containing protein 0.002 0.0045 0.0244
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit alpha 0.0429 0.2673 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0032 0.0123 0.0457
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0067 0.0343 0.6955
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0082 0.044 0.044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.009 0.009
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0209 0.4248
Trichomonas vaginalis D-aminoacylase, putative 0.0046 0.0211 0.4273
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0067 0.0343 0.0343
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0027 0.009 0.0487
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0022 0.0058 0.0058
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0124 0.0711 0.0711
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0014 0.0007 0.0007
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0013 0.0001 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0233 0.4722
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0014 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0003
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0046 0.0211 0.0786
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.009 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0145 0.2946
Schistosoma mansoni smad1 5 8 and 0.002 0.0045 0.0045
Onchocerca volvulus 0.0029 0.0103 0.1389
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0168 0.3396
Plasmodium falciparum phenylalanine--tRNA ligase 0.0026 0.0081 0.1646
Onchocerca volvulus 0.0128 0.0737 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0022 0.0058 0.1163
Brugia malayi hypothetical protein 0.0014 0.0007 0.0036
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0046 0.0211 0.0787
Mycobacterium tuberculosis Probable lipase LipE 0.0046 0.0211 0.0787
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0003 0.0018
Schistosoma mansoni tar DNA-binding protein 0.0082 0.0439 0.0439
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit alpha 0.0429 0.2673 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.009 0.0487
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0013 0.0001 0.0004
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0027 0.0088 0.0088
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0067 0.0343 0.6955
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0067 0.0343 0.6955
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0013 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0233 0.4722
Brugia malayi nuclear receptor NHR-88 0.0027 0.009 0.0487
Schistosoma mansoni sterol O-acyltransferase 1 0.0137 0.0794 0.0794
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0067 0.0343 0.1858
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0027 0.009 0.009
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0209 0.1134
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0018 0.0033 0.0033
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0067 0.0343 0.6955
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0145 0.2939
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0082 0.044 0.044
Schistosoma mansoni tar DNA-binding protein 0.0082 0.0439 0.0439
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0014 0.0007 0.0007
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0046 0.0209 0.0782
Echinococcus multilocularis TGF beta signal transducer SmadC 0.002 0.0045 0.0045
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0022 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0046 0.0211 0.1143
Echinococcus granulosus TGF beta signal transducer SmadC 0.002 0.0045 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0233 0.4722
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0145 0.2946
Entamoeba histolytica hypothetical protein 0.0027 0.0088 0.177
Schistosoma mansoni steroid hormone receptor ad4bp 0.0027 0.009 0.009
Schistosoma mansoni retinoic acid receptor RXR 0.0027 0.009 0.009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0027 0.009 0.0489
Loa Loa (eye worm) CXXC zinc finger family protein 0.0027 0.0087 0.0469
Loa Loa (eye worm) transcription factor SMAD2 0.03 0.1844 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0343 0.6955
Echinococcus multilocularis geminin 0.0358 0.2219 0.2219
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0026 0.0081 0.0081
Brugia malayi photoreceptor-specific nuclear receptor 0.0027 0.009 0.0487
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0038
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0001 0.0001
Echinococcus granulosus survival motor neuron protein 1 0.0224 0.1354 0.1354
Schistosoma mansoni hypothetical protein 0.0046 0.0208 0.0208
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0013 0.0001 0.0001
Toxoplasma gondii target of rapamycin (TOR), putative 0.005 0.0233 0.4722
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0007 0.0036
Brugia malayi phenylalanyl-tRNA synthetase, mitochondrial precursor, putative 0.0026 0.0081 0.0439
Echinococcus granulosus GPCR family 2 0.0082 0.044 0.044
Loa Loa (eye worm) phosphatidylinositol 3 0.0067 0.0343 0.1858
Loa Loa (eye worm) phenylalanyl-tRNA synthetase 0.0026 0.0081 0.0442
Schistosoma mansoni ap endonuclease 0.0067 0.0343 0.0343
Leishmania major pantothenate kinase subunit, putative 0.0015 0.0013 0.0245
Trichomonas vaginalis esterase, putative 0.0046 0.0211 0.4273
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0067 0.0343 0.6955
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0145 0.2946
Echinococcus granulosus sterol O acyltransferase 1 0.0137 0.0794 0.0794
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0026 0.0081 0.1646
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0022 0.0058 0.1163
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0209 0.4248
Schistosoma mansoni hypothetical protein 0.0082 0.044 0.044
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0003
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0053 0.0255 0.5179
Loa Loa (eye worm) hypothetical protein 0.0259 0.1577 0.855
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0067 0.0343 0.6955
Treponema pallidum phenylalanyl-tRNA synthetase subunit alpha 0.009 0.0493 1
Brugia malayi MH2 domain containing protein 0.002 0.0045 0.0244
Loa Loa (eye worm) oxidoreductase 0.0013 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0046 0.0211 0.1143
Loa Loa (eye worm) hypothetical protein 0.0034 0.013 0.0703
Loa Loa (eye worm) latrophilin receptor protein 2 0.0082 0.044 0.2386
Loa Loa (eye worm) hypothetical protein 0.0027 0.009 0.0489
Echinococcus multilocularis ecdysone induced protein 78C 0.0027 0.009 0.009
Brugia malayi ecdysteroid receptor 0.0027 0.009 0.0487
Trichomonas vaginalis penicillin-binding protein, putative 0.0046 0.0211 0.4273
Schistosoma mansoni hypothetical protein 0.0358 0.2219 0.2219
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.017 0.3448
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0085 0.1709
Brugia malayi exodeoxyribonuclease III family protein 0.0067 0.0343 0.1856
Mycobacterium leprae conserved hypothetical protein 0.0046 0.0211 0.6477
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.028 0.5681
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0013 0.0001 0.0004
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0067 0.0343 0.6955
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0259 0.1577 0.8549
Mycobacterium ulcerans hypothetical protein 0.0046 0.0209 0.0781
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0001 0.0001
Plasmodium falciparum acyl-CoA synthetase 0.0034 0.0135 0.2729
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0023 0.0466
Schistosoma mansoni ap endonuclease 0.0067 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.0082 0.044 0.2386
Loa Loa (eye worm) hypothetical protein 0.0027 0.009 0.0489
Brugia malayi MH2 domain containing protein 0.002 0.0045 0.0244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0192 0.3898
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0027 0.009 0.009
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0046 0.0208 0.1124
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0027 0.009 0.0489
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0067 0.0343 0.6955
Echinococcus multilocularis cpg binding protein 0.003 0.0106 0.0106
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0053 0.0255 0.5179
Loa Loa (eye worm) hypothetical protein 0.0177 0.1051 0.5697
Schistosoma mansoni cpg binding protein 0.003 0.0106 0.0106
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0082 0.044 0.2384
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0027 0.009 0.009
Schistosoma mansoni ferritin 0.002 0.0044 0.0044
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0067 0.0343 0.6955
Brugia malayi AMP-binding enzyme family protein 0.0013 0.0001 0.0001
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0082 0.044 0.044
Loa Loa (eye worm) hypothetical protein 0.0046 0.0211 0.1143
Entamoeba histolytica hypothetical protein 0.0027 0.0088 0.177
Mycobacterium ulcerans bacterioferritin BfrA 0.002 0.0044 0.0162
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0058 0.1163
Loa Loa (eye worm) hypothetical protein 0.0027 0.009 0.0489
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0027 0.009 0.0489
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0343 0.6955
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0038
Brugia malayi Bromodomain containing protein 0.0058 0.0286 0.1547
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0209 0.6439
Onchocerca volvulus 0.0046 0.0208 0.2812
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0027 0.009 0.009
Trichomonas vaginalis D-aminoacylase, putative 0.0046 0.0211 0.4273
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0013 0.0001 0.0004
Schistosoma mansoni thyroid hormone receptor 0.0027 0.009 0.009
Brugia malayi beta-lactamase 0.0046 0.0211 0.114
Schistosoma mansoni transcription factor LCR-F1 0.0027 0.0088 0.0088
Echinococcus granulosus cpg binding protein 0.003 0.0106 0.0106
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0067 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0027 0.009 0.0489
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0027 0.009 0.009
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0209 0.4248
Echinococcus granulosus chromobox protein 1 0.0067 0.0344 0.0344
Echinococcus multilocularis microtubule associated protein 2 0.1568 1 1
Brugia malayi AMP-binding enzyme family protein 0.0013 0.0001 0.0001
Toxoplasma gondii propionate-CoA ligase 0.0013 0.0001 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0023 0.0466
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0145 0.2946
Echinococcus multilocularis Smad4 0.002 0.0045 0.0045
Loa Loa (eye worm) Smad1 0.002 0.0045 0.0246
Plasmodium falciparum phenylalanine--tRNA ligase 0.0026 0.0081 0.1646
Brugia malayi hypothetical protein 0.0027 0.0088 0.0472
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0023 0.0466
Trichomonas vaginalis D-aminoacylase, putative 0.0046 0.0211 0.4273
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0082 0.044 0.044
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0027 0.009 0.0487
Toxoplasma gondii phenylalanyl-tRNA synthetase alpha chain A, putative 0.009 0.0493 1
Brugia malayi beta-lactamase family protein 0.0046 0.0211 0.114
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0067 0.0343 0.1136
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0013 0 0.0003
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0013 0 0.0003
Mycobacterium tuberculosis Bacterioferritin BfrB 0.002 0.0044 0.0162
Brugia malayi hypothetical protein 0.0014 0.0007 0.0036
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.009 0.009
Leishmania major hypothetical protein, conserved 0.0046 0.0211 0.4273
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0124 0.0711 0.0711
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0023 0.0466
Echinococcus granulosus ferritin 0.002 0.0044 0.0044
Schistosoma mansoni chromobox protein 0.0067 0.0344 0.0344
Trichomonas vaginalis chromobox protein, putative 0.004 0.0173 0.3511
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0014 0.0004 0.0077
Loa Loa (eye worm) RNA binding protein 0.0082 0.0439 0.2381
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0085 0.1709
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0209 0.1134
Plasmodium vivax acyl-CoA synthetase, putative 0.0034 0.0135 0.2729
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0032 0.0123 0.0457
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0013 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0155 0.3139
Trypanosoma brucei phenylalanyl-tRNA synthetase alpha chain, putative 0.009 0.0493 1
Echinococcus granulosus Smad4 0.002 0.0045 0.0045
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0209 0.6439
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0209 0.4248
Brugia malayi PHD-finger family protein 0.002 0.0044 0.0236
Mycobacterium ulcerans bacterioferritin BfrB 0.002 0.0044 0.0162
Onchocerca volvulus Protein ultraspiracle homolog 0.0027 0.009 0.1217
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0067 0.0343 0.6955
Schistosoma mansoni cellular tumor antigen P53 0.0128 0.0737 0.0737
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0046 0.0209 0.0781
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.017 0.3448
Plasmodium vivax acetyl-CoA synthetase, putative 0.0013 0.0001 0.0004
Echinococcus multilocularis chromobox protein 1 0.0067 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.0046 0.0209 0.1136
Loa Loa (eye worm) hypothetical protein 0.0046 0.0209 0.1136
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.009 0.009
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0027 0.0087 0.0087
Echinococcus multilocularis GPCR, family 2 0.0082 0.044 0.044
Onchocerca volvulus 0.0046 0.0211 0.2853
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0026 0.0081 0.1646
Loa Loa (eye worm) steroid hormone receptor 0.0027 0.009 0.0489
Onchocerca volvulus 0.0027 0.009 0.1217
Schistosoma mansoni hypothetical protein 0.0177 0.1051 0.1051
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0077
Onchocerca volvulus 0.0027 0.0087 0.1168
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0211 0.4273
Echinococcus multilocularis ferritin 0.002 0.0044 0.0044
Schistosoma mansoni acetyl-CoA synthetase 0.0013 0.0001 0.0001
Schistosoma mansoni RAR-like nuclear receptor 0.0027 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0034 0.0135 0.0731
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0022 0.0058 0.1163
Loa Loa (eye worm) PHD-finger family protein 0.0015 0.0014 0.0073
Brugia malayi Latrophilin receptor protein 2 0.0082 0.044 0.2384
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0067 0.0343 0.6955
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0013 0.0001 0.0001
Echinococcus granulosus fetal alzheimer antigen falz 0.0018 0.0033 0.0033
Schistosoma mansoni coup transcription factor 0.0027 0.009 0.009
Echinococcus multilocularis expressed protein 0.002 0.0044 0.0044
Echinococcus granulosus phenylalanyl tRNA synthetase 0.0026 0.0081 0.0081
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0124 0.0711 0.3854
Schistosoma mansoni smad1 5 8 and 0.002 0.0045 0.0045
Onchocerca volvulus Bile acid receptor homolog 0.0027 0.009 0.1217
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0027 0.009 0.009
Echinococcus granulosus tumor protein p63 0.0875 0.554 0.554
Loa Loa (eye worm) hypothetical protein 0.0053 0.0255 0.1384
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.009 0.0487
Trichomonas vaginalis penicillin-binding protein, putative 0.0046 0.0211 0.4273
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0027 0.009 0.0489
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0027 0.009 0.1217
Schistosoma mansoni ferritin light chain 0.002 0.0044 0.0044
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0344 0.6979
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0067 0.0343 0.0343
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0023 0.0466
Onchocerca volvulus 0.0046 0.0209 0.2836
Brugia malayi nuclear receptor RXR 0.0014 0.0007 0.0036
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0014 0.0007 0.0038
Loa Loa (eye worm) hypothetical protein 0.0027 0.009 0.0489
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0015 0.0013 0.0245
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0022 0.0058 0.1163
Echinococcus multilocularis smad 0.002 0.0045 0.0045
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0032 0.0117 0.2362
Schistosoma mansoni nuclear hormone receptor 0.0027 0.009 0.009
Onchocerca volvulus 0.0016 0.0019 0.0245
Loa Loa (eye worm) hypothetical protein 0.0027 0.009 0.0489
Leishmania major phenylalanyl-tRNA synthetase alpha chain, putative 0.009 0.0493 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0027 0.009 0.0489
Brugia malayi beta-lactamase family protein 0.0046 0.0211 0.114
Brugia malayi latrophilin 2 splice variant baaae 0.0177 0.1051 0.5696
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.009 0.0487
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0046 0.0212 0.0212
Mycobacterium ulcerans hypothetical protein 0.0046 0.0211 0.0786
Trichomonas vaginalis ap endonuclease, putative 0.0067 0.0343 0.6955
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0007
Brugia malayi MH1 domain containing protein 0.002 0.0045 0.0244
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0046 0.0211 0.0787
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0027 0.009 0.0487
Schistosoma mansoni apoferritin-2 0.002 0.0044 0.0044
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.009 0.0493 1
Onchocerca volvulus 0.0046 0.0211 0.2853
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0124 0.0711 0.3852
Schistosoma mansoni survival motor neuron protein 0.0046 0.0208 0.0208
Treponema pallidum bacterioferrin (TpF1) 0.002 0.0044 0.0882
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0145 0.2939
Loa Loa (eye worm) hypothetical protein 0.0029 0.0103 0.0558
Schistosoma mansoni smad 0.002 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0034 0.0135 0.0731
Giardia lamblia GTOR 0.0067 0.0343 0.6955
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.002 0.0044 0.0162
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0002 0.0039
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0027 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0046 0.0209 0.1136
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.009 0.009
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0022 0.0058 0.1163
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0058 0.1163
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0013 0.0001 0.0004
Schistosoma mansoni cpg binding protein 0.003 0.0106 0.0106
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0067 0.0343 0.0343
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0027 0.009 0.0487
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0255 0.5172
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0082 0.044 0.044
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0046 0.0211 0.1143
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0046 0.0211 0.114
Trichomonas vaginalis ap endonuclease, putative 0.0067 0.0343 0.6955
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0013 0.0001 0.0001
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0013 0 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.009 0.0487
Schistosoma mansoni ferritin 0.002 0.0044 0.0044
Brugia malayi AMP-binding enzyme family protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0082 0.0439 0.2381
Loa Loa (eye worm) hypothetical protein 0.0046 0.0211 0.1143
Loa Loa (eye worm) hypothetical protein 0.0027 0.009 0.0489
Loa Loa (eye worm) MH2 domain-containing protein 0.03 0.1844 1
Schistosoma mansoni smad1 5 8 and 0.002 0.0045 0.0045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0027 0.009 0.0489
Trypanosoma cruzi phenylalanyl-tRNA synthetase alpha chain, putative 0.009 0.0493 1
Toxoplasma gondii ABC1 family protein 0.0046 0.0211 0.4273
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0046 0.0211 0.0787
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.002 0.0044 0.1331
Loa Loa (eye worm) MH1 domain-containing protein 0.002 0.0045 0.0246
Schistosoma mansoni hypothetical protein 0.0082 0.044 0.044
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0013 0.0001 0.0004
Leishmania major phosphatidylinositol 3-kinase, putative 0.0022 0.0058 0.1163
Echinococcus multilocularis thyroid hormone receptor alpha 0.0027 0.009 0.009
Mycobacterium ulcerans lipase LipD 0.0046 0.0211 0.0786
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0252 0.5121
Mycobacterium leprae Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.0064 0.0325 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0067 0.0343 0.128
Echinococcus granulosus mothers against decapentaplegic 5 0.002 0.0045 0.0045
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0067 0.0343 0.6955
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0057 0.028 0.028
Loa Loa (eye worm) MH2 domain-containing protein 0.002 0.0045 0.0246
Schistosoma mansoni hypothetical protein 0.0082 0.044 0.044
Schistosoma mansoni ferritin 0.002 0.0044 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0027 0.009 0.0487
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0058 0.1163
Schistosoma mansoni Smad4 0.002 0.0045 0.0045
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.0003 0.0003
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0013 0.0001 0.0004
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0022 0.0058 0.0058
Trichomonas vaginalis antibiotic synthetase, putative 0.0013 0.0001 0.0004
Brugia malayi CXXC zinc finger family protein 0.0027 0.0087 0.0467
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0124 0.0711 0.0711
Echinococcus granulosus phenylalanyl tRNA synthetase alpha chain B 0.009 0.0493 0.0493
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0046 0.0209 0.0781
Loa Loa (eye worm) TAR-binding protein 0.0082 0.0439 0.2381
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0255 0.5172
Trichomonas vaginalis chromobox protein, putative 0.004 0.0173 0.3511
Entamoeba histolytica hypothetical protein 0.0027 0.0088 0.177
Treponema pallidum exodeoxyribonuclease (exoA) 0.0067 0.0343 0.6955
Loa Loa (eye worm) hypothetical protein 0.0034 0.0135 0.0731
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0013 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0031 0.0111 0.0599
Loa Loa (eye worm) hypothetical protein 0.0224 0.1354 0.7342
Loa Loa (eye worm) hypothetical protein 0.0128 0.0737 0.3998
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0058 0.0313
Schistosoma mansoni ferritin 0.002 0.0044 0.0044
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0027 0.0087 0.0087
Echinococcus granulosus tar DNA binding protein 0.0082 0.0439 0.0439
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0023 0.0466
Mycobacterium tuberculosis Probable lipase LipD 0.0046 0.0211 0.0787
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0343 0.6955
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0209 0.0781
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0259 0.1577 0.855
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0027 0.009 0.009
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0067 0.0343 0.6955
Mycobacterium tuberculosis Probable hydrolase 0.0046 0.0211 0.0787
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0233 0.4722
Echinococcus multilocularis mothers against decapentaplegic 5 0.002 0.0045 0.0045
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0067 0.0343 0.6955
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0028 0.0092 0.186
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.0003 0.0003
Onchocerca volvulus 0.0046 0.0211 0.2853
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0013 0.0001 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0209 0.0781
Trypanosoma brucei hypothetical protein, conserved 0.0046 0.0211 0.4273
Echinococcus multilocularis FTZ F1 alpha 0.0027 0.009 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0233 0.4722

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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