Detailed information for compound 105432

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 689.227 | Formula: C34H37ClN8O4S
  • H donors: 1 H acceptors: 5 LogP: 2.25 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: Clc1ccc2c(c1)cc([nH]2)S(=O)(=O)N1CCN(C(C1)CC(=O)N1CCN(CC1)c1ccncc1)C(=O)c1ccc(cc1)C1=NCCN1C
  • InChi: 1S/C34H37ClN8O4S/c1-39-13-12-37-33(39)24-2-4-25(5-3-24)34(45)43-19-18-42(48(46,47)31-21-26-20-27(35)6-7-30(26)38-31)23-29(43)22-32(44)41-16-14-40(15-17-41)28-8-10-36-11-9-28/h2-11,20-21,29,38H,12-19,22-23H2,1H3
  • InChiKey: PCQGTBCWZBDGQE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens coagulation factor X Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis myo-inositol transporter, putative 0.0065 0.0251 0.1057
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0017 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0824 0.3569
Trypanosoma brucei sugar transporter, putative 0.0065 0.0251 0.0619
Schistosoma mansoni rab6-interacting 0.0021 0.0024 0.0014
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0106 0.0423
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0041 0.0066
Mycobacterium ulcerans hypothetical protein 0.0023 0.0035 0.0571
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0179 0.0169
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0142 0.0644 0.1037
Loa Loa (eye worm) beta-lactamase 0.0037 0.0106 0.0258
Toxoplasma gondii glycyl-tRNA synthetase 0.0026 0.005 0.0044
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0097 0.0131
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0024 0.0014
Schistosoma mansoni biogenic amine receptor 0.002 0.0017 0.0002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0047 0.0167
Brugia malayi major facilitator superfamily protein 0.0065 0.0251 0.0629
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0024 0.0039
Loa Loa (eye worm) hypothetical protein 0.004 0.0122 0.0301
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0179 0.0834 0.2214
Loa Loa (eye worm) major facilitator superfamily transporter 0.0065 0.0251 0.0647
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0024 0.0039
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0109
Echinococcus multilocularis fmrfamide receptor 0.002 0.0017 0.0027
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.008 0.0128
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Brugia malayi hypothetical protein 0.0035 0.0097 0.0215
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Leishmania major threonyl-tRNA synthetase, putative 0.0026 0.005 0.0079
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0251 0.1057
Loa Loa (eye worm) hypothetical protein 0.0104 0.0447 0.1174
Onchocerca volvulus 0.0065 0.0251 0.2039
Brugia malayi Bromodomain containing protein 0.003 0.0069 0.0141
Echinococcus granulosus synaptic vesicle 2 protein 0.0065 0.0251 0.0404
Trichomonas vaginalis glucose transporter, putative 0.0144 0.0653 0.2821
Schistosoma mansoni ap endonuclease 0.002 0.0021 0.0009
Onchocerca volvulus 0.0065 0.0251 0.2039
Chlamydia trachomatis lysine--tRNA ligase 0.0104 0.0447 1
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0065 0.0251 0.0619
Echinococcus granulosus glycyl tRNA synthetase 0.0026 0.005 0.0081
Echinococcus granulosus allatostatin A receptor 0.002 0.0017 0.0027
Schistosoma mansoni protein kinase 0.0142 0.0644 0.1015
Echinococcus multilocularis dnaJ subfamily B 0.0869 0.4371 0.7039
Loa Loa (eye worm) melatonin receptor type 1A 0.002 0.0017 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0017 0.0027
Schistosoma mansoni hypothetical protein 0.1228 0.6209 1
Onchocerca volvulus 0.0065 0.0251 0.2039
Schistosoma mansoni growth hormone secretagogue receptor 0.002 0.0017 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0658 0.1038
Schistosoma mansoni jumonji domain containing protein 0.0137 0.0619 0.0974
Echinococcus granulosus sex peptide receptor 0.002 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0262 0.1259 0.3355
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0039
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0026 0.005 0.0079
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0464 0.2292 0.3692
Loa Loa (eye worm) serotonin transporter b 0.0062 0.0233 0.0598
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0021 0.005
Trypanosoma brucei glucose transporter, putative 0.0144 0.0653 0.1704
Brugia malayi beta-lactamase family protein 0.0037 0.0106 0.024
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Brugia malayi jmjC domain containing protein 0.0025 0.0047 0.0082
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0026 0.005 0.0926
Loa Loa (eye worm) hypothetical protein 0.0067 0.026 0.0671
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0464 0.2292 0.3692
Schistosoma mansoni hypothetical protein 0.002 0.0017 0.0002
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Giardia lamblia Prolyl-tRNA synthetase 0.0139 0.0629 0.1113
Schistosoma mansoni cpg binding protein 0.0061 0.0229 0.0345
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Loa Loa (eye worm) TYRA-2 protein 0.002 0.0017 0.0019
Brugia malayi Cam kinase protein 1 0.0142 0.0644 0.1688
Loa Loa (eye worm) histone methyltransferase 0.002 0.0019 0.0025
Echinococcus multilocularis geminin 0.1228 0.6209 1
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0309 0.1502 0.2709
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Plasmodium falciparum lysine--tRNA ligase 0.0104 0.0447 0.0438
Echinococcus multilocularis serotonin receptor 0.002 0.0017 0.0027
Schistosoma mansoni hypothetical protein 0.003 0.0069 0.0086
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0047 0.0101
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0142 0.0644 0.0944
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.002 0.0017 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0295 0.0452
Onchocerca volvulus Alhambra homolog 0.003 0.0069 0.0457
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.002 0.0017 0.0027
Echinococcus granulosus solute carrier family 22 0.0065 0.0251 0.0404
Schistosoma mansoni hypothetical protein 0.0179 0.0834 0.1322
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0139 0.0629 0.1113
Mycobacterium tuberculosis Conserved protein 0.0037 0.0106 0.0903
Echinococcus granulosus solute carrier family 22 0.0065 0.0251 0.0404
Loa Loa (eye worm) hypothetical protein 0.0037 0.0106 0.0258
Loa Loa (eye worm) hypothetical protein 0.0066 0.0253 0.0655
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0179 0.0426
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0024 0.0039
Onchocerca volvulus Glucosylceramidase homolog 0.0177 0.0824 0.7041
Echinococcus multilocularis serotonin receptor 0.002 0.0017 0.0027
Mycobacterium ulcerans sugar transporter 0.0065 0.0251 0.5511
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0069 0.0086
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0017 0.0027
Echinococcus multilocularis phd:f box containing protein 0.0025 0.0047 0.0076
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0041 0.0721
Leishmania major hypothetical protein, conserved 0.0023 0.0035 0.0037
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0106 0.0258
Onchocerca volvulus 0.005 0.0175 0.1376
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0142 0.0644 0.1037
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0035 0.0037
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0251 0.1057
Trichomonas vaginalis CAMK family protein kinase 0.0142 0.0644 0.278
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0179 0.0426
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0017 0.0002
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0083 0.0341 0.055
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0251 0.1057
Echinococcus granulosus lysine specific demethylase 5A 0.0099 0.0424 0.0683
Schistosoma mansoni amine GPCR 0.002 0.0017 0.0002
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.002 0.0017 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.008 0.0103
Schistosoma mansoni hypothetical protein 0.0083 0.0341 0.0526
Mycobacterium tuberculosis Conserved protein 0.0037 0.0106 0.0903
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0138 0.0623 0.1623
Echinococcus granulosus phd:f box containing protein 0.0025 0.0047 0.0076
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0749 0.3756 0.375
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Echinococcus granulosus acetylcholinesterase 0.0066 0.0253 0.0408
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0065 0.0251 0.5511
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.002 0.0017 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0035 0.0111
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0021 0.0145
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0824 0.3569
Echinococcus granulosus 7TM GPCR rhodopsin 0.002 0.0017 0.0027
Echinococcus granulosus lysyl tRNA synthetase 0.0104 0.0447 0.072
Echinococcus granulosus neuropeptide receptor A26 0.0469 0.2319 0.3734
Giardia lamblia Threonyl-tRNA synthetase 0.0026 0.005 0.0054
Schistosoma mansoni cpg binding protein 0.0065 0.0247 0.0374
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0139 0.0629 0.2716
Echinococcus granulosus neuropeptide receptor 0.002 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0037 0.0106 0.0258
Plasmodium vivax CDK-related protein kinase 6, putative 0.1968 1 1
Giardia lamblia Sugar-proton symporter 0.0065 0.0251 0.042
Loa Loa (eye worm) hypothetical protein 0.0083 0.0341 0.089
Treponema pallidum sodium- and chloride- dependent transporter 0.0062 0.0233 1
Schistosoma mansoni hypothetical protein 0.0869 0.4371 0.7032
Trypanosoma brucei glucose transporter 1E 0.0144 0.0653 0.1704
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0138 0.0561
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.001 0.0045
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.002 0.0017 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0047 0.0167
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Echinococcus granulosus lysine specific demethylase 6a 0.0025 0.0047 0.0076
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0295 0.0452
Brugia malayi Heterochromatin protein 1 0.0072 0.0283 0.0716
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0138 0.0561
Brugia malayi RNA binding protein 0.0074 0.0295 0.075
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0251 0.1057
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0179 0.0169
Plasmodium falciparum calcium-dependent protein kinase 1 0.0142 0.0644 0.0635
Brugia malayi Major Facilitator Superfamily protein 0.0065 0.0251 0.0629
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0017 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0015 0.0023
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Schistosoma mansoni hypothetical protein 0.0083 0.0341 0.0526
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0021 0.0011
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Echinococcus granulosus Threonyl tRNA synthetase C 0.0026 0.005 0.0081
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0017 0.0027
Echinococcus multilocularis calcium dependent protein kinase 0.0133 0.0599 0.0965
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0142 0.0644 0.1679
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0126 0.056 0.0901
Loa Loa (eye worm) hypothetical protein 0.0381 0.1867 0.4989
Loa Loa (eye worm) hypothetical protein 0.0025 0.0047 0.0101
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0139 0.0629 0.0991
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0017 0.0002
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.002 0.0017 0.0019
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0088 0.0367 0.323
Loa Loa (eye worm) hypothetical protein 0.0037 0.0106 0.0258
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0017 0.0002
Loa Loa (eye worm) hypothetical protein 0.0139 0.0629 0.1664
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0047 0.0167
Trichomonas vaginalis set domain proteins, putative 0.0243 0.1163 0.5055
Schistosoma mansoni hypothetical protein 0.0023 0.0034 0.003
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0026 0.005 0.0179
Loa Loa (eye worm) hypothetical protein 0.0139 0.0629 0.1664
Onchocerca volvulus Putative transporter 0.0065 0.0251 0.2039
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0021 0.0034
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0162 0.0747 0.1957
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0026 0.005 0.0926
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0017 0.0027
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0041 0.0326
Echinococcus granulosus thyrotropin releasing hormone receptor 0.002 0.0017 0.0027
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0017 0.0027
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0157 0.0721 0.1162
Giardia lamblia Lysyl-tRNA synthetase 0.0104 0.0447 0.0779
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0017 0.0002
Echinococcus granulosus serotonin transporter 0.0062 0.0233 0.0374
Schistosoma mansoni hypothetical protein 0.002 0.0017 0.0002
Loa Loa (eye worm) solute carrier family 6 member 4 0.0062 0.0233 0.0598
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Brugia malayi hypothetical protein 0.0051 0.0179 0.0437
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0047 0.0167
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0024 0.0039
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0104 0.0447 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0041 0.0111
Mycobacterium ulcerans integral membrane transport protein 0.0065 0.0251 0.5511
Loa Loa (eye worm) hypothetical protein 0.0025 0.0047 0.0101
Trypanosoma cruzi Emopamil binding protein, putative 0.0138 0.0623 0.1623
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0139 0.0629 0.1013
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0041 0.0055
Loa Loa (eye worm) carboxylesterase 0.0066 0.0253 0.0655
Onchocerca volvulus 0.0243 0.1163 1
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0749 0.3756 0.5652
Echinococcus granulosus peregrin 0.003 0.0069 0.0111
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0024 0.0039
Giardia lamblia Hexose transporter 0.0065 0.0251 0.042
Onchocerca volvulus 0.0021 0.0024 0.0064
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0142 0.0644 0.1037
Plasmodium vivax threonine--tRNA ligase, putative 0.0026 0.005 0.0041
Leishmania major hypothetical protein, conserved 0.0065 0.0251 0.0619
Giardia lamblia Glycyl-tRNA synthetase 0.0026 0.005 0.0054
Schistosoma mansoni hypothetical protein 0.0083 0.0341 0.0526
Trypanosoma brucei glucose transporter, putative 0.0144 0.0653 0.1704
Plasmodium falciparum mitogen-activated protein kinase 2 0.0749 0.3756 0.375
Plasmodium falciparum calcium-dependent protein kinase 3 0.0142 0.0644 0.0635
Toxoplasma gondii transporter, major facilitator family protein 0.0065 0.0251 0.0348
Schistosoma mansoni hypothetical protein 0.002 0.0017 0.0002
Schistosoma mansoni amine GPCR 0.002 0.0017 0.0002
Brugia malayi Calcitonin receptor-like protein seb-1 0.0262 0.1259 0.3342
Plasmodium vivax hypothetical protein, conserved 0.003 0.0069 0.006
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0021 0.005
Toxoplasma gondii sugar transporter ST1 0.0065 0.0251 0.0348
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0658 0.1038
Brugia malayi Pre-SET motif family protein 0.0032 0.008 0.0169
Loa Loa (eye worm) RNA binding protein 0.0074 0.0295 0.0767
Brugia malayi Major Facilitator Superfamily protein 0.0065 0.0251 0.0629
Brugia malayi Sugar transporter family protein 0.0065 0.0251 0.0629
Schistosoma mansoni sugar transporter 0.0065 0.0251 0.0379
Echinococcus multilocularis tar DNA binding protein 0.0074 0.0295 0.0476
Echinococcus granulosus tachykinin peptides receptor 99D 0.002 0.0017 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0017 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0062 0.023
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0846 0.4253 0.685
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0106 0.0903
Echinococcus multilocularis chromobox protein 1 0.0072 0.0283 0.0456
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0041 0.0721
Leishmania major hypothetical protein, conserved 0.0051 0.0179 0.0426
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0138 0.0623 0.1623
Brugia malayi chromobox protein homolog 3 0.004 0.0122 0.0283
Plasmodium vivax glycine--tRNA ligase, putative 0.0026 0.005 0.0041
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0464 0.2292 0.3692
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Schistosoma mansoni lipoxygenase 0.0088 0.0366 0.0566
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0017 0.0027
Loa Loa (eye worm) acetylcholinesterase 1 0.0066 0.0253 0.0655
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Schistosoma mansoni glucose transport protein 0.0464 0.2292 0.3676
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.1181 0.1902
Echinococcus granulosus Sugar transporter ERD6 protein 0.0065 0.0251 0.0404
Trypanosoma brucei C-8 sterol isomerase, putative 0.0745 0.3733 1
Giardia lamblia DNA repair protein RAD52 0.1088 0.5489 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0106 0.0146
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0104 0.0447 0.1147
Schistosoma mansoni adenoreceptor 0.002 0.0017 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0017 0.0019
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0129 0.0208
Loa Loa (eye worm) hypothetical protein 0.0062 0.0233 0.0598
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0017 0.0027
Leishmania major glucose transporter, lmgt3 0.0144 0.0653 0.1704
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.008 0.0103
Brugia malayi jmjC domain containing protein 0.0025 0.0047 0.0082
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0041 0.0037
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0658 0.106
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0824 0.3569
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.002 0.0017 0.0019
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.008 0.0089
Schistosoma mansoni neuropeptide receptor 0.002 0.0017 0.0002
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0017 0.0027
Onchocerca volvulus 0.0065 0.0251 0.2039
Echinococcus granulosus G protein coupled receptor 139 0.002 0.0017 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Toxoplasma gondii lysine-tRNA ligase 0.0104 0.0447 0.0645
Mycobacterium tuberculosis Conserved protein 0.0037 0.0106 0.0903
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Trypanosoma brucei Emopamil binding protein, putative 0.0138 0.0623 0.1623
Loa Loa (eye worm) sugar transporter 0.0065 0.0251 0.0647
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0065 0.0251 0.0241
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0047 0.0071
Onchocerca volvulus 0.0031 0.0078 0.053
Brugia malayi Major Facilitator Superfamily protein 0.0065 0.0251 0.0629
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0162 0.0747 0.1957
Brugia malayi hypothetical protein 0.0065 0.0251 0.0629
Echinococcus granulosus RUN 0.0021 0.0024 0.0039
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0745 0.3733 1
Echinococcus multilocularis synaptic vesicle 2 protein 0.0065 0.0251 0.0404
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0735 0.3683 0.9866
Trypanosoma brucei glucose transporter 2A 0.0144 0.0653 0.1704
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0069 0.0073
Trypanosoma cruzi hexose transporter, putative 0.0144 0.0653 0.1704
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0017 0.0027
Echinococcus multilocularis jumonji domain containing 1A 0.0025 0.0047 0.0076
Schistosoma mansoni glucose transporter 0.0065 0.0251 0.0379
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Schistosoma mansoni cpg binding protein 0.0065 0.0247 0.0374
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0139 0.0629 0.1648
Echinococcus multilocularis solute carrier family 22 0.0065 0.0251 0.0404
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0025 0.0047 0.0051
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Schistosoma mansoni amine GPCR 0.002 0.0017 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.003 0.0069 0.016
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0658 0.106
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0283 0.1198
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0097 0.0156
Plasmodium vivax JmjC domain containing protein 0.0025 0.0047 0.0037
Echinococcus multilocularis g protein coupled receptor 0.002 0.0017 0.0027
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0026 0.005 0.0054
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0041 0.0721
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0015 0.0023
Trichomonas vaginalis esterase, putative 0.0037 0.0106 0.0423
Schistosoma mansoni sugar transporter 0.0065 0.0251 0.0379
Brugia malayi lysyl-tRNA synthetase 0.0104 0.0447 0.1157
Onchocerca volvulus 0.0065 0.0251 0.2039
Onchocerca volvulus 0.0065 0.0251 0.2039
Brugia malayi RNA recognition motif domain containing protein 0.0074 0.0295 0.075
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.0653 0.2821
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0106 0.0423
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0283 0.0734
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0104 0.0447 1
Mycobacterium leprae Probable lipase LipE 0.0037 0.0106 0.1198
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0017 0.0027
Plasmodium vivax calcium-dependent protein kinase, putative 0.0142 0.0644 0.0635
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0142 0.0644 0.1037
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0464 0.2292 0.3692
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0062 0.023
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0138 0.0623 0.1623
Onchocerca volvulus 0.0065 0.0251 0.2039
Trypanosoma brucei glucose transporter, putative 0.0144 0.0653 0.1704
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.13 0.5652
Echinococcus multilocularis neuropeptide receptor 0.002 0.0017 0.0027
Giardia lamblia PHD finger protein 15 0.003 0.0069 0.0088
Leishmania major glucose transporter, lmgt2 0.0144 0.0653 0.1704
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0104 0.0447 0.1147
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0106 0.0096
Schistosoma mansoni loxhd1 0.0021 0.0024 0.0014
Brugia malayi Carboxylesterase family protein 0.0066 0.0253 0.0637
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0026 0.005 0.0044
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0251 0.0619
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0179 0.0239
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0017 0.0027
Schistosoma mansoni amine GPCR 0.002 0.0017 0.0002
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0262 0.1259 0.3342
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0104 0.0447 0.1916
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0253 0.0408
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0041 0.0721
Echinococcus multilocularis solute carrier family 22 0.0065 0.0251 0.0404
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0106 0.0229
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0026 0.005 0.0406
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0283 0.1198
Echinococcus multilocularis lysine specific demethylase 5A 0.0096 0.0406 0.0654
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0065 0.0251 0.2193
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0464 0.2292 0.3692
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0047 0.0167
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0106 0.0171
Toxoplasma gondii sugar transporter ST2 0.0065 0.0251 0.0348
Treponema pallidum threonyl-tRNA synthetase 0.0026 0.005 0.1386
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0062 0.0233 0.035
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0106 0.0903
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0229 0.059
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.008 0.0128
Brugia malayi Doublecortin family protein 0.0021 0.0024 0.002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0017 0.0027
Echinococcus granulosus somatostatin receptor 0.002 0.0017 0.0027
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0145 0.0658 0.1727
Onchocerca volvulus 0.0065 0.0251 0.2039
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0232 0.0596
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0049 0.0168 0.3628
Echinococcus granulosus calcium dependent protein kinase 0.0133 0.0599 0.0965
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0142 0.0644 0.1704
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0142 0.0644 0.1688
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0088 0.0367 0.323
Echinococcus multilocularis GPCR, family 2 0.0083 0.0341 0.055
Brugia malayi beta-lactamase 0.0037 0.0106 0.024
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0017 0.0027
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0162 0.0747 0.1099
Echinococcus granulosus g protein coupled receptor 0.002 0.0017 0.0027
Echinococcus granulosus g protein coupled receptor 0.002 0.0017 0.0027
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0067 0.0108
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0069 0.0073
Chlamydia trachomatis threonine--tRNA ligase 0.0026 0.005 0.0926
Trypanosoma brucei THT1 - hexose transporter, putative 0.0144 0.0653 0.1704
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0142 0.0644 0.0635
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Echinococcus multilocularis G protein coupled receptor 139 0.002 0.0017 0.0027
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0106 0.0903
Schistosoma mansoni protein phosphatase 2C 0.0025 0.0047 0.0051
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0145 0.0658 0.1742
Echinococcus granulosus alpha 1A adrenergic receptor 0.002 0.0017 0.0027
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0065 0.0251 0.2193
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0065 0.0251 1
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0026 0.005 0.0079
Toxoplasma gondii sugar transporter ST3 0.0065 0.0251 0.0348
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0026 0.005 0.009
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Onchocerca volvulus 0.0061 0.0229 0.1854
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0017 0.0019
Trypanosoma cruzi hexose transporter, putative 0.0144 0.0653 0.1704
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0644 0.1015
Onchocerca volvulus 0.0062 0.0233 0.1882
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0142 0.0644 0.0635
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Trypanosoma brucei THT1 - hexose transporter, putative 0.0144 0.0653 0.1704
Echinococcus granulosus peptide allatostatin:somatostatin 0.002 0.0017 0.0027
Plasmodium falciparum protein kinase 7 0.131 0.6629 0.6626
Schistosoma mansoni amine GPCR 0.002 0.0017 0.0002
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0017 0.0019
Brugia malayi hypothetical protein 0.0021 0.0024 0.002
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0017 0.0027
Chlamydia trachomatis proline--tRNA ligase 0.0049 0.0168 0.3628
Plasmodium falciparum threonine--tRNA ligase 0.0026 0.005 0.0041
Entamoeba histolytica hypothetical protein 0.0035 0.0097 0.0138
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0464 0.2292 0.3692
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0295 0.0452
Loa Loa (eye worm) hypothetical protein 0.0051 0.0179 0.0455
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0024 0.0039
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Brugia malayi MH2 domain containing protein 0.0127 0.0568 0.1482
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0017 0.0002
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0139 0.0629 0.1648
Echinococcus granulosus acetylcholinesterase 0.0066 0.0253 0.0408
Brugia malayi jmjC domain containing protein 0.0025 0.0047 0.0082
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0069 0.0111
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0106 0.22
Mycobacterium ulcerans hypothetical protein 0.0024 0.0041 0.0721
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.002 0.0017 0.0002
Schistosoma mansoni peptide (allatostatin)-like receptor 0.002 0.0017 0.0002
Echinococcus multilocularis g protein coupled receptor 0.002 0.0017 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0017 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.008 0.0103
Echinococcus granulosus hypothetical protein 0.002 0.0017 0.0027
Mycobacterium ulcerans lipase LipD 0.0037 0.0106 0.22
Echinococcus multilocularis lysine specific demethylase 6a 0.0025 0.0047 0.0076
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0041 0.0721
Brugia malayi hypothetical protein 0.0021 0.0024 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0251 0.1057
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0017 0.0027
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0142 0.0644 0.1037
Echinococcus granulosus orexin receptor type 2 0.002 0.0017 0.0027
Leishmania major C-8 sterol isomerase-like protein 0.0745 0.3733 1
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0065 0.0251 0.0404
Schistosoma mansoni jumonji/arid domain-containing protein 0.0099 0.0424 0.066
Schistosoma mansoni myosin xvIII 0.002 0.0017 0.0002
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0122 0.0917
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0041 0.0111
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0142 0.0644 0.1037
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0025 0.0047 0.004
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0017 0.0027
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0026 0.005 0.0081
Leishmania major glucose transporter/membrane transporter D2, putative 0.0144 0.0653 0.1704
Schistosoma mansoni opsin-like receptor 0.002 0.0017 0.0002
Echinococcus multilocularis serotonin transporter 0.0062 0.0233 0.0374
Trichomonas vaginalis sugar transport protein, putative 0.0065 0.0251 0.1057
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0106 0.0229
Entamoeba histolytica protein kinase, putative 0.0142 0.0644 0.114
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0026 0.005 0.0262
Echinococcus multilocularis neuropeptide receptor A26 0.0469 0.2319 0.3734
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0021 0.0011
Schistosoma mansoni histamine h1 receptor 0.002 0.0017 0.0002
Trypanosoma cruzi Emopamil binding protein, putative 0.0138 0.0623 0.1623
Echinococcus multilocularis peregrin 0.003 0.0069 0.0111
Schistosoma mansoni glucose transport protein 0.0464 0.2292 0.3676
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0873 0.3783
Leishmania major hypothetical protein, conserved 0.0023 0.0035 0.0037
Echinococcus multilocularis G-protein coupled receptor, putative 0.002 0.0017 0.0027
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.002 0.0017 0.0027
Schistosoma mansoni opsin-like receptor 0.002 0.0017 0.0002
Loa Loa (eye worm) hypothetical protein 0.0066 0.0253 0.0655
Toxoplasma gondii facilitative glucose transporter GT1 0.0464 0.2292 0.3437
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0106 0.0423
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0097 0.0156
Echinococcus multilocularis solute carrier family 22 0.0065 0.0251 0.0404
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0142 0.0644 0.0635
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Echinococcus granulosus 7tm_1 domain containing protein 0.002 0.0017 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Echinococcus multilocularis orexin receptor type 2 0.002 0.0017 0.0027
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0017 0.0002
Trichomonas vaginalis glucose transporter, putative 0.0144 0.0653 0.2821
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Brugia malayi jmjC domain containing protein 0.0157 0.0721 0.1896
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0017 0.0027
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0047 0.0071
Schistosoma mansoni sugar transporter 0.0065 0.0251 0.0379
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0031 0.0078 0.0182
Echinococcus granulosus cpg binding protein 0.0065 0.0247 0.0398
Echinococcus multilocularis lysyl tRNA synthetase 0.0104 0.0447 0.072
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.0188
Schistosoma mansoni alpha-1 adrenergic receptor 0.002 0.0017 0.0002
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0464 0.2292 0.3692
Plasmodium vivax proline--tRNA ligase, putative 0.0162 0.0747 0.0738
Schistosoma mansoni phd/f-box containing protein 0.0025 0.0047 0.0051
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0026 0.005 0.009
Loa Loa (eye worm) major facilitator superfamily transporter 0.0065 0.0251 0.0647
Schistosoma mansoni jumonji/arid domain-containing protein 0.0099 0.0424 0.066
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0047 0.0101
Schistosoma mansoni jumonji domain containing protein 0.0025 0.0047 0.0051
Plasmodium falciparum JmjC domain-containing protein, putative 0.0025 0.0047 0.0037
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0106 0.024
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0106 0.0258
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0066 0.0253 0.0384
Loa Loa (eye worm) hypothetical protein 0.0745 0.3733 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0017 0.0002
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0142 0.0644 0.0944
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0138 0.1053
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Brugia malayi hypothetical protein 0.0033 0.0086 0.0186
Echinococcus multilocularis neuropeptide receptor 0.002 0.0017 0.0027
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0088 0.0367 0.5587
Schistosoma mansoni hypothetical protein 0.1228 0.6209 1
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0025 0.0047 0.0071
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0142 0.0644 0.1037
Schistosoma mansoni lysyl-tRNA synthetase 0.0104 0.0447 0.0696
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0017 0.0002
Echinococcus granulosus serotonin receptor 0.002 0.0017 0.0027
Brugia malayi Sugar transporter family protein 0.0065 0.0251 0.0629
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Schistosoma mansoni neuropeptide receptor 0.002 0.0017 0.0002
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.008 0.0128
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.002 0.0017 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Echinococcus multilocularis alpha 1A adrenergic receptor 0.002 0.0017 0.0027
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0157 0.0721 0.1162
Schistosoma mansoni neuropeptide f receptor 76f 0.002 0.0017 0.0002
Brugia malayi jmjC domain containing protein 0.0025 0.0047 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0824 0.3569
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0017 0.0027
Brugia malayi hypothetical protein 0.0065 0.0251 0.0629
Loa Loa (eye worm) TAR-binding protein 0.0074 0.0295 0.0767
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0026 0.005 0.0109
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.13 0.5652
Echinococcus multilocularis sex peptide receptor 0.002 0.0017 0.0027
Schistosoma mansoni opsin-like receptor 0.002 0.0017 0.0002
Leishmania major protein kinase, putative 0.0142 0.0644 0.1679
Onchocerca volvulus 0.0065 0.0251 0.2039
Onchocerca volvulus 0.0065 0.0251 0.2039
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0024 0.0039
Trypanosoma cruzi glucose transporter, putative 0.0065 0.0251 0.0619
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.027 0.13 0.3452
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0041 0.0066
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0106 0.1198
Plasmodium falciparum hexose transporter 0.0464 0.2292 0.2285
Entamoeba histolytica hypothetical protein 0.0104 0.0447 0.0779
Schistosoma mansoni biogenic amine receptor 0.002 0.0017 0.0002
Brugia malayi jmjC domain containing protein 0.0099 0.0424 0.1096
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0106 0.0903
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0017 0.0002
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0023 0.0035 0.0037
Loa Loa (eye worm) latrophilin receptor protein 2 0.0083 0.0341 0.089
Trypanosoma brucei glucose transporter, putative 0.0144 0.0653 0.1704
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0017 0.0027
Echinococcus granulosus fmrfamide receptor 0.002 0.0017 0.0027
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.002 0.0017 0.0019
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0106 0.0423
Plasmodium falciparum phd finger protein, putative 0.003 0.0069 0.006
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0026 0.005 0.0079
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0085
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0106 0.0423
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0065 0.0251 0.0379
Echinococcus multilocularis dro:myosuppressin receptor 0.002 0.0017 0.0027
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0023 0.0035 0.0037
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0253 0.0408
Plasmodium vivax lysine--tRNA ligase, putative 0.0104 0.0447 0.0438
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0035 0.0268
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Echinococcus granulosus dnaJ subfamily B 0.0869 0.4371 0.7039
Schistosoma mansoni phosphatidylserine receptor 0.0025 0.0047 0.0051
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Onchocerca volvulus 0.0044 0.014 0.1072
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0065 0.0251 0.5511
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0023 0.0035 0.0021
Trypanosoma brucei glucose transporter, putative 0.0144 0.0653 0.1704
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0515 0.0747
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0262 0.1259 0.3355
Onchocerca volvulus 0.0065 0.0251 0.2039
Schistosoma mansoni ap endonuclease 0.002 0.0021 0.0009
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0069 0.0111
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.002 0.0017 0.0027
Echinococcus multilocularis solute carrier family 22 0.0065 0.0251 0.0404
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0041 0.0721
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.13 0.5652
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Plasmodium vivax sugar transporter, putative 0.0065 0.0251 0.0241
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0069 0.016
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0126 0.056 0.0901
Loa Loa (eye worm) norepinephrine transporter 0.0062 0.0233 0.0598
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0057 0.0209 0.0536
Trypanosoma cruzi hexose transporter 0.0144 0.0653 0.1704
Schistosoma mansoni hypothetical protein 0.0035 0.0097 0.0131
Echinococcus multilocularis neuropeptide FF receptor 2 0.002 0.0017 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0035 0.0111
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0162 0.0747 0.1957
Trypanosoma brucei glucose transporter, putative 0.0144 0.0653 0.1704
Trypanosoma cruzi sugar transporter, putative 0.0065 0.0251 0.0619
Echinococcus multilocularis cpg binding protein 0.0065 0.0247 0.0398
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Echinococcus multilocularis glycyl tRNA synthetase 0.0026 0.005 0.0081
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0023 0.0035 0.0037
Brugia malayi major facilitator superfamily protein 0.0065 0.0251 0.0629
Trichomonas vaginalis sugar transporter, putative 0.0144 0.0653 0.2821
Plasmodium falciparum proline--tRNA ligase 0.0162 0.0747 0.0738
Schistosoma mansoni glycyl-tRNA synthetase 0.0026 0.005 0.0056
Leishmania major hypothetical protein, conserved 0.0037 0.0106 0.0229
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0047 0.0101
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0041 0.0721
Schistosoma mansoni hypothetical protein 0.0464 0.2292 0.3676
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0142 0.0644 0.0944
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0017 0.0027
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0017 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0047 0.0167
Echinococcus granulosus neuropeptide s receptor 0.0469 0.2319 0.3734
Echinococcus multilocularis allatostatin A receptor 0.002 0.0017 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0017 0.0002
Onchocerca volvulus 0.0065 0.0251 0.2039
Echinococcus granulosus neuropeptide FF receptor 2 0.002 0.0017 0.0027
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0162 0.0747 0.1957
Schistosoma mansoni lipoxygenase 0.0126 0.056 0.0878
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0824 0.3569
Schistosoma mansoni survival motor neuron protein 0.005 0.0175 0.0257
Trypanosoma cruzi hexose transporter, putative 0.0079 0.0319 0.0804
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0873 0.3783
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0175 0.0424
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0062 0.0233 0.0581
Brugia malayi glycyl-tRNA synthetase 0.0026 0.005 0.009
Brugia malayi latrophilin 2 splice variant baaae 0.0179 0.0834 0.2199
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0106 0.0903
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0104 0.0447 0.6932
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0017 0.0002
Entamoeba histolytica hypothetical protein 0.0035 0.0097 0.0138
Plasmodium falciparum calcium-dependent protein kinase 2 0.0142 0.0644 0.0635
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0083 0.0341 0.0873
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0017 0.0002
Onchocerca volvulus 0.0021 0.0024 0.0064
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0017 0.0027
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0029 0.0065 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0106 0.0229
Loa Loa (eye worm) hypothetical protein 0.0062 0.0233 0.0598
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0106 0.0146
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0106 0.0903
Trypanosoma brucei THT1 - hexose transporter, putative 0.0144 0.0653 0.1704
Loa Loa (eye worm) transcription factor SMAD2 0.0127 0.0568 0.1498
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0017 0.0002
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0236 0.1126 1
Brugia malayi Latrophilin receptor protein 2 0.0083 0.0341 0.0873
Brugia malayi CXXC zinc finger family protein 0.0061 0.0229 0.0572
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0017 0.0027
Schistosoma mansoni protein kinase 0.0142 0.0644 0.1015
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0024 0.0014
Echinococcus granulosus jumonji domain containing 1A 0.0025 0.0047 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0035 0.0037
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.1181 0.1902
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0017 0.0027
Leishmania major glucose transporter, lmgt1 0.0144 0.0653 0.1704
Loa Loa (eye worm) hypothetical protein 0.0037 0.0106 0.0258
Mycobacterium ulcerans hypothetical protein 0.0037 0.0106 0.22
Brugia malayi PHD-finger family protein 0.003 0.0069 0.0141
Schistosoma mansoni biogenic amine receptor 0.002 0.0017 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Plasmodium falciparum calcium-dependent protein kinase 5 0.0142 0.0644 0.0635
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Onchocerca volvulus 0.0024 0.0041 0.0214
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0017 0.0002
Schistosoma mansoni chromobox protein 0.0072 0.0283 0.0432
Echinococcus multilocularis somatostatin receptor 0.002 0.0017 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Echinococcus granulosus neuropeptide receptor 0.002 0.0017 0.0027
Echinococcus multilocularis chromobox protein 1 0.0072 0.0283 0.0456
Brugia malayi Sugar transporter family protein 0.0464 0.2292 0.6123
Loa Loa (eye worm) MH2 domain-containing protein 0.0127 0.0568 0.1498
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0021 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Schistosoma mansoni neuropeptide receptor 0.002 0.0017 0.0002
Schistosoma mansoni lysyl-tRNA synthetase 0.0104 0.0447 0.0696
Toxoplasma gondii protein kinase, putative 0.131 0.6629 1
Echinococcus granulosus dro:myosuppressin receptor 0.002 0.0017 0.0027
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.1088 0.5489 1
Echinococcus granulosus General substrate transporter 0.0399 0.1958 0.3154
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.13 0.5652
Echinococcus multilocularis General substrate transporter 0.0399 0.1958 0.3154
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0122 0.0493
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0041 0.0037
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0017 0.0027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0658 0.1038
Leishmania major myo-inositol/proton symporter (MIT) 0.0065 0.0251 0.0619
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0026 0.005 0.1277
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0658 0.106
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0041 0.0055
Schistosoma mansoni polycystin 1-related 0.0021 0.0024 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.0653 0.2821
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.014 0.02
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0026 0.005 0.0054
Loa Loa (eye worm) hypothetical protein 0.0247 0.1181 0.3146
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Plasmodium vivax hexose transporter 0.0464 0.2292 0.2285
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0179 0.0169
Echinococcus granulosus solute carrier family 22 0.0065 0.0251 0.0404
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Schistosoma mansoni glucose transport protein 0.0464 0.2292 0.3676
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0179 0.0426
Plasmodium falciparum calcium-dependent protein kinase 4 0.0142 0.0644 0.0635
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0083 0.0341 0.055
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Brugia malayi Pre-SET motif family protein 0.0214 0.1013 0.268
Brugia malayi follicle stimulating hormone receptor 0.0735 0.3683 0.9866
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0026 0.005 0.1277
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0162 0.0747 0.1957
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0021 0.003
Onchocerca volvulus 0.0065 0.0251 0.2039
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0026 0.005 0.0109
Echinococcus multilocularis JmjC domain containing protein 4 0.0025 0.0047 0.0076
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.002 0.0017 0.0002
Entamoeba histolytica hypothetical protein 0.0309 0.1502 0.2709
Entamoeba histolytica protein kinase, putative 0.0142 0.0644 0.114
Trypanosoma brucei glucose transporter, putative 0.0144 0.0653 0.1704
Echinococcus granulosus g-protein coupled receptor 0.002 0.0017 0.0027
Echinococcus multilocularis carboxylesterase 5A 0.0066 0.0253 0.0408
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0035 0.0111
Onchocerca volvulus 0.0138 0.0623 0.529
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0083 0.0341 0.055
Loa Loa (eye worm) hypothetical protein 0.0062 0.0233 0.0598
Leishmania major hypothetical protein, conserved 0.0025 0.0047 0.0071
Schistosoma mansoni hypothetical protein 0.0021 0.0024 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0295 0.0452
Echinococcus multilocularis g-protein coupled receptor 0.002 0.0017 0.0027
Schistosoma mansoni neuropeptide receptor 0.002 0.0017 0.0002
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0034 0.0055
Echinococcus granulosus geminin 0.1228 0.6209 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0085
Loa Loa (eye worm) sugar transporter 0.0464 0.2292 0.613
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0106 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0251 0.1057
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0041 0.0055
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0017 0.0019
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0019 0.0031
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0106 0.22
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.027 0.13 0.3464
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0139 0.0629 0.0991
Echinococcus granulosus GPCR family 2 0.0083 0.0341 0.055
Treponema pallidum prolyl-tRNA synthetase 0.0049 0.0168 0.6967
Schistosoma mansoni rab6-interacting 0.0021 0.0024 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0017 0.0027
Brugia malayi Carboxylesterase family protein 0.0066 0.0253 0.0637
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0034 0.0055
Onchocerca volvulus 0.0037 0.0106 0.0778
Echinococcus granulosus g protein coupled receptor 0.002 0.0017 0.0027
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0029 0.0065 0.0105
Entamoeba histolytica hypothetical protein 0.0035 0.0097 0.0138
Loa Loa (eye worm) hypothetical protein 0.0037 0.0106 0.0258
Echinococcus granulosus carboxylesterase 5A 0.0066 0.0253 0.0408
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0139 0.0629 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0085
Echinococcus granulosus tar DNA binding protein 0.0074 0.0295 0.0476
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.13 0.5652
Echinococcus multilocularis fmrfamide receptor 0.002 0.0017 0.0027
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0019 0.0031
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.002 0.0017 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0122 0.0493
Loa Loa (eye worm) hypothetical protein 0.0142 0.0644 0.1704
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0142 0.0644 0.1037
Echinococcus granulosus chromobox protein 1 0.0072 0.0283 0.0456
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0824 0.3569
Schistosoma mansoni hypothetical protein 0.0083 0.0341 0.0526
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0041 0.0066
Echinococcus multilocularis neuropeptide s receptor 0.0469 0.2319 0.3734
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.13 0.5652
Echinococcus multilocularis tachykinin peptides receptor 99D 0.002 0.0017 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0295 0.0452
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0464 0.2292 0.3692
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0131 0.0586 0.092
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0083 0.0341 0.055
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.002 0.0017 0.0027
Trypanosoma brucei glucose transporter, putative 0.0144 0.0653 0.1704
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0214 0.1013 0.2694
Echinococcus granulosus solute carrier family 22 0.0065 0.0251 0.0404
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0129 0.0208
Trypanosoma cruzi hexose transporter, putative 0.0144 0.0653 0.1704
Schistosoma mansoni hypothetical protein 0.002 0.0021 0.0009
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0106 0.0903
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0017 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0017 0.0027
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.002 0.0017 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0144 0.0653 0.2821
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0647
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.005 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0464 0.2292 1
Schistosoma mansoni chromobox protein 0.0072 0.0283 0.0432
Brugia malayi hypothetical protein 0.0247 0.1181 0.3133
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0142 0.0644 0.1704
Brugia malayi TAR-binding protein 0.0074 0.0295 0.075
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0139 0.0629 0.1013
Mycobacterium ulcerans beta-lactamase 0.0037 0.0106 0.22
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0047 0.0167
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.002 0.0017 0.0027
Loa Loa (eye worm) jmjC domain-containing protein 0.0099 0.0424 0.1113
Plasmodium vivax SET domain protein, putative 0.0032 0.008 0.007
Loa Loa (eye worm) hypothetical protein 0.0113 0.0496 0.1305
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0658 0.106
Echinococcus granulosus chromobox protein 1 0.0072 0.0283 0.0456
Onchocerca volvulus 0.0037 0.0106 0.0778
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0017 0.0027
Toxoplasma gondii ABC1 family protein 0.0037 0.0106 0.0129
Leishmania major lysyl-tRNA synthetase, putative 0.0104 0.0447 0.1147
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0026 0.005 0.0079
Echinococcus multilocularis RUN 0.0021 0.0024 0.0039
Schistosoma mansoni protein kinase 0.0142 0.0644 0.1015
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Brugia malayi beta-lactamase family protein 0.0037 0.0106 0.024
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0824 0.3569
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0021 0.0011
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0745 0.3733 1
Brugia malayi hypothetical protein 0.0065 0.0251 0.0629
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0021 0.0255
Onchocerca volvulus 0.0065 0.0251 0.2039
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0041 0.0037
Schistosoma mansoni hypothetical protein 0.002 0.0017 0.0002
Schistosoma mansoni sugar transporter 0.0065 0.0251 0.0379
Onchocerca volvulus 0.0037 0.0106 0.0778
Leishmania major hypothetical protein, conserved 0.0138 0.0623 0.1623
Entamoeba histolytica hypothetical protein 0.0035 0.0097 0.0138
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0017 0.0027
Onchocerca volvulus 0.0065 0.0251 0.2039
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.002 0.0017 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0144 0.0653 0.2821
Schistosoma mansoni hypothetical protein 0.005 0.0175 0.0257
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.002 0.0017 0.0002
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.002 0.0017 0.0027
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0017 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0041 0.0326
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0047 0.0167
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0068 0.0137
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0019
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0025 0.0047 0.004
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0251 0.1057
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0017 0.0002
Onchocerca volvulus 0.0065 0.0251 0.2039
Echinococcus granulosus JmjC domain containing protein 4 0.0025 0.0047 0.0076
Schistosoma mansoni sodium/chloride dependent transporter 0.0062 0.0233 0.035
Echinococcus multilocularis g protein coupled receptor 0.002 0.0017 0.0027
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0074 0.0295 0.0767
Echinococcus multilocularis biogenic amine (5HT) receptor 0.002 0.0017 0.0027
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0091 0.0381 0.163

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 8 nM In vitro inhibitory activity against Coagulation factor X was determined ChEMBL. 15080981
IC50 (binding) = 8 nM In vitro inhibitory activity against Coagulation factor X was determined ChEMBL. 15080981

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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