Detailed information for compound 1123863

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 377.782 | Formula: C16H16ClN5O4
  • H donors: 4 H acceptors: 6 LogP: 0.95 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1OC([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2Nc1cccc(c1)Cl
  • InChi: 1S/C16H16ClN5O4/c17-8-2-1-3-9(4-8)21-14-11-15(19-6-18-14)22(7-20-11)16-13(25)12(24)10(5-23)26-16/h1-4,6-7,10,12-13,16,23-25H,5H2,(H,18,19,21)/t10-,12-,13-,16?/m1/s1
  • InChiKey: TZNHRMFCCGYSTQ-AARXTDBFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.019 0.1112 0.1105
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0197 0.0898
Mycobacterium ulcerans hypothetical protein 0.0025 0.0091 0.0255
Brugia malayi protein C24B5.3 0.0012 0.0011 0.0023
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0235 0.0485
Onchocerca volvulus 0.0351 0.2114 1
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0019 0.0022
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0461 0.097
Onchocerca volvulus 0.0088 0.0482 0.225
Leishmania major phosphoglycerate kinase C, glycosomal 0.0173 0.1007 0.4711
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0067 0.0189
Schistosoma mansoni chromobox protein 0.0071 0.0375 0.0785
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0072 0.038 0.333
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0351 0.2114 1
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0067 0.0278
Brugia malayi Papain family cysteine protease containing protein 0.0351 0.2114 0.4521
Loa Loa (eye worm) hypothetical protein 0.0231 0.1369 0.2916
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0088 0.0482 0.225
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0164 0.0739
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0088 0.0482 0.1015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Echinococcus multilocularis expressed conserved protein 0.0185 0.1084 0.1077
Loa Loa (eye worm) hypothetical protein 0.0053 0.0268 0.0556
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0088 0.0482 0.225
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0088 0.0482 0.1015
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0018 0.0046 0.008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0765 0.4676 1
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0067 0.0098
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0088 0.0482 0.225
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0216 0.0446
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0018 0.0046 0.008
Mycobacterium ulcerans hypothetical protein 0.0072 0.038 0.333
Trypanosoma cruzi cysteine peptidase, putative 0.0351 0.2114 0.4496
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0201 0.0915
Loa Loa (eye worm) hypothetical protein 0.0088 0.0482 0.1015
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0046 0.0098
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0216 0.0446
Plasmodium vivax unspecified product 0.012 0.0681 0.3196
Loa Loa (eye worm) hypothetical protein 0.0085 0.0461 0.097
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Onchocerca volvulus 0.0012 0.0011 0.0011
Entamoeba histolytica cysteine proteinase, putative 0.0208 0.1227 0.5787
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0067 0.0125
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0046 0.008
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0461 0.0453
Echinococcus multilocularis pyruvate kinase 0.0034 0.0146 0.0138
Brugia malayi hypothetical protein 0.0012 0.0008 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0351 0.2114 1
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0173 0.1007 0.4744
Brugia malayi AMP-binding enzyme family protein 0.0072 0.038 0.0812
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0164 0.0334
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0049 0.0196
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0351 0.2114 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0088 0.0482 0.225
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0072 0.038 0.333
Loa Loa (eye worm) fibroinase 0.0351 0.2114 0.4511
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0146 0.0656
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.038 0.1765
Trypanosoma cruzi major cysteine proteinase, putative 0.0088 0.0482 0.099
Loa Loa (eye worm) hypothetical protein 0.0072 0.038 0.0796
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0088 0.0482 0.225
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0319 0.2677
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Echinococcus granulosus cathepsin L 0.0088 0.0482 0.1015
Giardia lamblia Cathepsin B precursor 0.0088 0.0482 0.2523
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0067 0.0189
Brugia malayi Papain family cysteine protease containing protein 0.0208 0.1227 0.2624
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0164 0.0739
Brugia malayi CHE-14 protein 0.0085 0.0461 0.0985
Schistosoma mansoni hypothetical protein 0.0048 0.0232 0.048
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0063 0.033 0.0662
Echinococcus multilocularis chromobox protein 1 0.0071 0.0375 0.0367
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0018 0.0046 0.0098
Entamoeba histolytica cysteine protease, putative 0.0208 0.1227 0.5787
Echinococcus multilocularis microtubule associated protein 2 0.07 0.4278 0.4273
Giardia lamblia Cathepsin B precursor 0.0088 0.0482 0.2523
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0046 0.008
Onchocerca volvulus 0.0351 0.2114 1
Loa Loa (eye worm) cathepsin B 0.0297 0.1779 0.3794
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.008
Onchocerca volvulus 0.0012 0.0011 0.0011
Schistosoma mansoni steroid hormone receptor ad4bp 0.0018 0.0046 0.008
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0088 0.0482 0.225
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0297 0.1779 0.8399
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0019 0.001
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0067 0.0098
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0018 0.0046 0.008
Loa Loa (eye worm) hypothetical protein 0.005 0.0248 0.0513
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0208 0.1227 0.576
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0091 0.0149
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0021 0.0062
Loa Loa (eye worm) hypothetical protein 0.0103 0.0576 0.1215
Onchocerca volvulus 0.0351 0.2114 1
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0319 0.0665
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0021 0.0062
Brugia malayi Papain family cysteine protease containing protein 0.0208 0.1227 0.2624
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0197 0.0405
Entamoeba histolytica cysteine protease, putative 0.0208 0.1227 0.5787
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.033 0.0662
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0021 0.0062
Loa Loa (eye worm) hypothetical protein 0.0053 0.0268 0.0556
Echinococcus multilocularis pyruvate kinase 0.0017 0.0044 0.0036
Giardia lamblia Cysteine protease 0.0088 0.0482 0.2523
Echinococcus multilocularis cathepsin L cysteine protease 0.0351 0.2114 0.2108
Entamoeba histolytica hypothetical protein 0.0037 0.0163 0.0734
Brugia malayi fibroinase precursor 0.0088 0.0482 0.1031
Loa Loa (eye worm) hypothetical protein 0.0055 0.0276 0.0574
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0351 0.2114 1
Entamoeba histolytica cysteine protease, putative 0.0208 0.1227 0.5787
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0067 0.0189
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2114 1
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0067 0.0278
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0235 0.0485
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0088 0.0482 0.2523
Loa Loa (eye worm) patched family protein 0.0012 0.0011 0.0005
Giardia lamblia Cathepsin B precursor 0.0088 0.0482 0.2523
Schistosoma mansoni hypothetical protein 0.0103 0.0576 0.1215
Entamoeba histolytica cysteine proteinase, putative 0.0231 0.1369 0.6463
Schistosoma mansoni chromobox protein 0.0071 0.0375 0.0785
Echinococcus multilocularis cathepsin b 0.0765 0.4676 0.4672
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0164 0.0739
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0163 0.0331
Brugia malayi Protein cec-1. 0.0012 0.0008 0.0018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.008
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0018 0.0046 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Brugia malayi cathepsin L-like cysteine proteinase 0.0088 0.0482 0.1031
Entamoeba histolytica cysteine protease, putative 0.0208 0.1227 0.5787
Toxoplasma gondii cathepsin B 0.0297 0.1779 0.8409
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0088 0.0482 0.225
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0067 0.0098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2114 1
Toxoplasma gondii cathepsin CPC2 0.0088 0.0482 0.225
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0297 0.0289
Trypanosoma cruzi cysteine peptidase, putative 0.0351 0.2114 0.4496
Echinococcus granulosus cathepsin L cysteine proteinase 0.0351 0.2114 0.4511
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0021 0.0062
Brugia malayi hypothetical protein 0.0012 0.0011 0.0023
Echinococcus granulosus Niemann Pick C1 protein 0.0282 0.1683 0.3587
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0173 0.1007 0.2118
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0319 0.0665
Loa Loa (eye worm) oxidoreductase 0.0021 0.0067 0.0125
Treponema pallidum phosphoglycerate kinase 0.0173 0.1007 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2114 1
Brugia malayi Phosphoglycerate kinase 0.0063 0.033 0.0705
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0351 0.2114 1
Onchocerca volvulus 0.0351 0.2114 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0018 0.0046 0.008
Toxoplasma gondii patched family protein 0.0012 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0351 0.2114 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0046 0.008
Brugia malayi Cathepsin L-like precursor 0.0351 0.2114 0.4521
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0019 0.0022
Toxoplasma gondii patched family protein 0.0012 0.0011 0.0011
Entamoeba histolytica cysteine protease, putative 0.0088 0.0482 0.225
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0083 0.016
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.038 0.333
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0297 0.2453
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0046 0.008
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0018 0.0046 0.008
Brugia malayi CXXC zinc finger family protein 0.0029 0.0119 0.0254
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0351 0.2114 0.4511
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0197 0.1158 0.5461
Giardia lamblia Cathepsin B precursor 0.0297 0.1779 1
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0083 0.0354
Mycobacterium ulcerans phosphoglycerate kinase 0.0173 0.1007 1
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0232 0.048
Echinococcus multilocularis protein patched 0.0085 0.0461 0.0453
Giardia lamblia Cathepsin L precursor 0.0088 0.0482 0.2523
Loa Loa (eye worm) hypothetical protein 0.012 0.0681 0.1442
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0276 0.0268
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0248 0.0513
Mycobacterium tuberculosis Conserved protein 0.0025 0.0091 0.0439
Plasmodium vivax serine-repeat antigen (SERA) 0.0088 0.0482 0.225
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0021 0.0062
Schistosoma mansoni cathepsin F (C01 family) 0.0231 0.1369 0.2916
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Chlamydia trachomatis phosphoglycerate kinase 0.0173 0.1007 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Entamoeba histolytica cysteine protease, putative 0.0208 0.1227 0.5787
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0046 0.0037
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0072 0.038 0.3456
Plasmodium vivax phosphoglycerate kinase, putative 0.0173 0.1007 0.4744
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0268 0.1232
Loa Loa (eye worm) hypothetical protein 0.024 0.1424 0.3033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0351 0.2114 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0018 0.0046 0.0178
Schistosoma mansoni hypothetical protein 0.0082 0.0442 0.0929
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2114 1
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0067 0.0125
Schistosoma mansoni alpha-glucosidase 0.0142 0.0819 0.1736
Toxoplasma gondii patched family protein 0.0012 0.0011 0.0011
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0072 0.038 0.333
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0067 0.0278
Giardia lamblia Cathepsin L precursor 0.0088 0.0482 0.2523
Plasmodium falciparum cysteine proteinase falcipain 3 0.0351 0.2114 1
Echinococcus multilocularis phosphoglycerate kinase 1 0.0173 0.1007 0.1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0164 0.0739
Trypanosoma brucei glucosidase, putative 0.0037 0.0164 0.0682
Brugia malayi Cathepsin L-like precursor 0.0351 0.2114 0.4521
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0146 0.0296
Plasmodium falciparum serine repeat antigen 4 0.0088 0.0482 0.225
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0319 0.1473
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0058 0.0297 0.132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2114 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0273 0.0567
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0088 0.0482 0.1015
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0067 0.0278
Brugia malayi Cathepsin L-like cysteine proteinase 0.0231 0.1369 0.2928
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0046 0.0098
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0044 0.0171
Brugia malayi Heterochromatin protein 1 0.0071 0.0375 0.0802
Trypanosoma cruzi cysteine peptidase, putative 0.0208 0.1227 0.259
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0962 0.0954
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0173 0.1007 0.4744
Trypanosoma cruzi cruzipain precursor, putative 0.0351 0.2114 0.4496
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0021 0.0062
Entamoeba histolytica cysteine proteinase, putative 0.0351 0.2114 1
Onchocerca volvulus 0.0351 0.2114 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0163 0.0155
Entamoeba histolytica hypothetical protein 0.0037 0.0163 0.0734
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0067 0.0189
Plasmodium vivax vivapain-1 0.0208 0.1227 0.5787
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0018 0.0046 0.008
Leishmania major cysteine peptidase A (CPA) 0.0351 0.2114 1
Loa Loa (eye worm) hypothetical protein 0.0231 0.1369 0.2916
Toxoplasma gondii cathepsin CPC1 0.0088 0.0482 0.225
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Toxoplasma gondii preprocathepsin c precursor, putative 0.0088 0.0482 0.225
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Echinococcus multilocularis cysteine protease 0.0351 0.2114 0.2108
Loa Loa (eye worm) patched family protein 0.0012 0.0011 0.0005
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0164 0.0739
Brugia malayi Cathepsin L-like precursor 0.012 0.0681 0.1457
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0088 0.0482 0.225
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0197 0.0898
Echinococcus multilocularis GPCR, family 2 0.0048 0.0232 0.0224
Brugia malayi cathepsin B-like cysteine proteinase 0.0765 0.4676 1
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0176 0.0757
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0049 0.0196
Brugia malayi Calcitonin receptor-like protein seb-1 0.0151 0.0871 0.1863
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0351 0.2114 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0216 0.0446
Onchocerca volvulus 0.0029 0.0119 0.0524
Loa Loa (eye worm) hypothetical protein 0.012 0.0681 0.1442
Entamoeba histolytica cysteine proteinase 2 0.0208 0.1227 0.5787
Echinococcus granulosus pyruvate kinase 0.0017 0.0044 0.0077
Echinococcus granulosus cathepsin l1 0.0351 0.2114 0.4511
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0018 0.0046 0.008
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0201 0.0915
Schistosoma mansoni cpg binding protein 0.0031 0.0129 0.0259
Entamoeba histolytica cysteine proteinase, putative 0.0208 0.1227 0.5787
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.0091 0.0391
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0216 0.0463
Entamoeba histolytica cysteine protease, putative 0.0088 0.0482 0.225
Leishmania major cathepsin L-like protease 0.0351 0.2114 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.038 0.333
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0216 0.0208
Echinococcus granulosus cathepsin b 0.0765 0.4676 1
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.033 0.1473
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0351 0.2114 0.4511
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0063 0.033 0.0662
Entamoeba histolytica cysteine protease, putative 0.0088 0.0482 0.225
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2114 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2114 1
Entamoeba histolytica cysteine proteinase 1, putative 0.0208 0.1227 0.5787
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0351 0.2114 1
Onchocerca volvulus 0.0351 0.2114 1
Entamoeba histolytica phosphoglycerate kinase, putative 0.0173 0.1007 0.4744
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0235 0.0227
Brugia malayi hypothetical protein 0.0012 0.0011 0.0023
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Plasmodium falciparum cysteine proteinase falcipain 1 0.0208 0.1227 0.5787
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0021 0.0062
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0216 0.0446
Brugia malayi follicle stimulating hormone receptor 0.0235 0.1394 0.298
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0351 0.2114 1
Schistosoma mansoni patched 1 0.0085 0.0461 0.097
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0018 0.0046 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2114 1
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0235 0.0485
Schistosoma mansoni phosphoglycerate kinase 0.0173 0.1007 0.214
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0088 0.0482 0.225
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0067 0.0217
Echinococcus granulosus lysosomal alpha glucosidase 0.0165 0.0962 0.2042
Brugia malayi Cathepsin L-like precursor 0.0351 0.2114 0.4521
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0067 0.0143
Schistosoma mansoni alpha-glucosidase 0.0142 0.0819 0.1736
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0044 0.0171
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0088 0.0482 0.225
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Schistosoma mansoni hypothetical protein 0.0048 0.0232 0.048
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0018 0.0046 0.008
Brugia malayi Cathepsin L-like precursor 0.0231 0.1369 0.2928
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0018 0.0046 0.0098
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.038 0.1765
Echinococcus multilocularis FTZ F1 alpha 0.0018 0.0046 0.0037
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0297 0.0636
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Onchocerca volvulus Cathepsin L homolog 0.0351 0.2114 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0046 0.008
Schistosoma mansoni cpg binding protein 0.0029 0.0119 0.0236
Toxoplasma gondii cathepsin CPL 0.0351 0.2114 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0216 0.0208
Onchocerca volvulus 0.0012 0.0011 0.0011
Echinococcus granulosus microtubule associated protein 2 0.07 0.4278 0.9147
Loa Loa (eye worm) hypothetical protein 0.0021 0.0067 0.0125
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0351 0.2114 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0351 0.2114 1
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0173 0.1007 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0176 0.0795
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0197 0.0898
Trypanosoma brucei phosphoglycerate kinase, putative 0.0063 0.033 0.1473
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2114 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0351 0.2114 1
Schistosoma mansoni hypothetical protein 0.0082 0.0442 0.0929
Plasmodium falciparum serine repeat antigen 3 0.0088 0.0482 0.225
Schistosoma mansoni phosphoglycerate kinase 0.0173 0.1007 0.214
Loa Loa (eye worm) hypothetical protein 0.0053 0.0268 0.0556
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0375 0.1741
Echinococcus granulosus Niemann Pick C1 protein 0.0197 0.1158 0.2464
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.1275 0.2693
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0119 0.0236
Onchocerca volvulus Protein patched homolog 0.0012 0.0011 0.0011
Echinococcus granulosus GPCR family 2 0.0048 0.0232 0.048
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0058 0.0297 0.0619
Loa Loa (eye worm) patched family protein 0.0012 0.0011 0.0005
Loa Loa (eye worm) hypothetical protein 0.0072 0.038 0.0796
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0164 0.0334
Plasmodium vivax unspecified product 0.0088 0.0482 0.225
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.1275 0.2693
Brugia malayi steroid hormone receptor 0.0018 0.0046 0.0098
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0231 0.1369 0.2896
Trypanosoma cruzi cysteine proteinase, putative 0.0208 0.1227 0.259
Schistosoma mansoni survival motor neuron protein 0.0049 0.024 0.0496
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0021 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0461 0.2149
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0088 0.0482 0.1015
Brugia malayi Patched related family protein 10 0.0012 0.0011 0.0023
Entamoeba histolytica cysteine protease, putative 0.0208 0.1227 0.5787
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0067 0.0189
Brugia malayi hypothetical protein 0.0012 0.0011 0.0023
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0268 0.2287
Loa Loa (eye worm) patched family protein 0.0012 0.0011 0.0005
Brugia malayi Patched related family protein 4 0.0012 0.0011 0.0023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0351 0.2114 1
Leishmania major pyruvate kinase 0.0034 0.0146 0.0598
Leishmania major pyruvate kinase 0.0034 0.0146 0.0598
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0351 0.2114 1
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Onchocerca volvulus 0.0012 0.0011 0.0011
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0091 0.0332
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.038 0.1714
Brugia malayi SET domain containing protein 0.0012 0.0012 0.0026
Mycobacterium ulcerans hypothetical protein 0.0025 0.0091 0.0255
Onchocerca volvulus 0.0012 0.0011 0.0011
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0146 0.0313
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0046 0.0098
Schistosoma mansoni cathepsin F (C01 family) 0.0351 0.2114 0.4511
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0235 0.0485
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2114 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0268 0.2138
Echinococcus granulosus FTZ F1 alpha 0.0018 0.0046 0.008
Brugia malayi Cathepsin L-like precursor 0.0351 0.2114 0.4521
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0297 0.1779 0.3794
Onchocerca volvulus 0.0072 0.038 0.1765
Echinococcus granulosus phosphoglycerate kinase 1 0.0173 0.1007 0.214
Giardia lamblia Cysteine protease 0.0088 0.0482 0.2523
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0201 0.0915
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0232 0.0224
Entamoeba histolytica cysteine proteinase, putative 0.0208 0.1227 0.5787
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0146 0.0656
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0276 0.0574
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Giardia lamblia Cathepsin L precursor 0.0088 0.0482 0.2523
Onchocerca volvulus Protein ultraspiracle homolog 0.0018 0.0046 0.0178
Trypanosoma cruzi cysteine protease, putative 0.0208 0.1227 0.259
Onchocerca volvulus 0.0048 0.0235 0.1076
Plasmodium falciparum serine repeat antigen 5 0.0088 0.0482 0.225
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0018 0.0046 0.0098
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0351 0.2114 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0088 0.0482 0.225
Giardia lamblia Phosphoglycerate kinase 0.0173 0.1007 0.5551
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0046 0.0037
Schistosoma mansoni retinoic acid receptor RXR 0.0018 0.0046 0.008
Loa Loa (eye worm) hypothetical protein 0.0351 0.2114 0.4511
Echinococcus granulosus pyruvate kinase 0.0034 0.0146 0.0296
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0164 0.0739
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0351 0.2114 1
Onchocerca volvulus Cathepsin F homolog 0.0351 0.2114 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0018 0.0046 0.0098
Loa Loa (eye worm) hypothetical protein 0.0173 0.1007 0.214
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0088 0.0482 0.225
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0208 0.1227 0.2611
Toxoplasma gondii patched family protein 0.0012 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0351 0.2114 1
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0276 0.0574
Loa Loa (eye worm) papain family cysteine protease containing protein 0.012 0.0681 0.1442
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0067 0.0189
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0197 0.0898
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0151 0.0871 0.1863
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0351 0.2114 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0088 0.0482 0.1015
Trypanosoma cruzi cruzipain precursor, putative 0.012 0.0681 0.1418
Leishmania major cathepsin L-like protease 0.0351 0.2114 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0088 0.0482 0.1015
Echinococcus multilocularis pyruvate kinase 0.0017 0.0044 0.0036
Trypanosoma brucei phosphoglycerate kinase 0.0173 0.1007 0.4711
Echinococcus multilocularis cathepsin L 0.0088 0.0482 0.0474
Schistosoma mansoni hypothetical protein 0.0293 0.175 0.3731
Schistosoma mansoni pyruvate kinase 0.0034 0.0146 0.0296
Brugia malayi Patched related family protein 12 0.0012 0.0011 0.0023
Echinococcus granulosus chromobox protein 1 0.0071 0.0375 0.0785
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0018 0.0046 0.008
Schistosoma mansoni cathepsin C 0.0088 0.0482 0.1015
Onchocerca volvulus 0.0021 0.0067 0.0278
Giardia lamblia Cathepsin L-like protease 0.0088 0.0482 0.2523
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0088 0.0482 0.225
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0067 0.0143
Brugia malayi ecdysteroid receptor 0.0018 0.0046 0.0098
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0021 0.0062
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0173 0.1007 0.4744
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.038 0.333
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.012 0.0681 0.1457
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0088 0.0482 0.225
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0058 0.0297 0.2596
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0049 0.0196
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0008 0.0018
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0067 0.0217
Toxoplasma gondii hypothetical protein 0.0012 0.0011 0.0011
Trypanosoma brucei cysteine peptidase C (CPC) 0.0297 0.1779 0.8399
Plasmodium vivax patched family protein, putative 0.0012 0.0011 0.0011
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0018 0.0046 0.008
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0019 0.0022
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0164 0.0739
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0072 0.038 0.333
Schistosoma mansoni cathepsin S (C01 family) 0.0088 0.0482 0.1015
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.003 0.0105
Loa Loa (eye worm) ctsf protein 0.0351 0.2114 0.4511
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0088 0.0482 0.1015
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0067 0.0058
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.0576 0.1231
Loa Loa (eye worm) hypothetical protein 0.0053 0.0268 0.0556
Loa Loa (eye worm) hypothetical protein 0.004 0.0182 0.0373
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0375 0.0785
Entamoeba histolytica cysteine protease, putative 0.0088 0.0482 0.225
Schistosoma mansoni cpg binding protein 0.0031 0.0129 0.0259
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0088 0.0482 0.225
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0067 0.0098
Plasmodium vivax vivapain-3 0.0208 0.1227 0.5787
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Trypanosoma brucei phosphoglycerate kinase 0.0063 0.033 0.1473
Entamoeba histolytica hypothetical protein 0.0037 0.0163 0.0734
Brugia malayi cathepsin Z-like cysteine proteinase 0.0088 0.0482 0.1031
Brugia malayi Myosin head containing protein 0.0012 0.0011 0.0023
Plasmodium falciparum pyruvate kinase 0.0034 0.0146 0.0656
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0235 0.0485
Brugia malayi mbt repeat family protein 0.0048 0.0235 0.0502
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0021 0.0045
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0319 0.2677
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2114 1
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.0091 0.0082
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0046 0.008
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0018 0.0046 0.0098
Schistosoma mansoni hypothetical protein 0.0082 0.0442 0.0929
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0182 0.0826
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0461 0.097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0231 0.1369 0.6463
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Brugia malayi Papain family cysteine protease containing protein 0.0088 0.0482 0.1031
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0088 0.0482 0.2523
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0164 0.0739
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0146 0.0847
Giardia lamblia Hypothetical protein 0.0088 0.0482 0.2523
Loa Loa (eye worm) hypothetical protein 0.0072 0.038 0.0796
Echinococcus multilocularis cathepsin L cysteine protease 0.0351 0.2114 0.2108
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0146 0.0598
Brugia malayi photoreceptor-specific nuclear receptor 0.0018 0.0046 0.0098
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Echinococcus granulosus survival motor neuron protein 1 0.024 0.1424 0.3033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0088 0.0482 0.225
Schistosoma mansoni cathepsin s 0.012 0.0681 0.1442
Loa Loa (eye worm) hypothetical protein 0.0765 0.4676 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0351 0.2114 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0323 0.0674
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0297 0.1779 0.3777
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0018 0.0046 0.008
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.0091 0.0255
Brugia malayi M-phase phosphoprotein, mpp8 0.0012 0.0008 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2114 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0146 0.0296
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0351 0.2114 0.2108
Giardia lamblia Cysteine protease 0.0088 0.0482 0.2523
Brugia malayi CHD4 protein 0.0013 0.0019 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0482 0.225
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0173 0.1007 0.2118
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0276 0.0574
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0018 0.0046 0.0037
Giardia lamblia Cysteine protease 0.0088 0.0482 0.2523
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0268 0.1232
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0049 0.0196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0231 0.1369 0.6463
Loa Loa (eye worm) steroid hormone receptor 0.0018 0.0046 0.008
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0276 0.0268
Echinococcus granulosus cathepsin l1 0.0231 0.1369 0.2916
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0962 0.0954
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0088 0.0482 0.2523
Plasmodium vivax unspecified product 0.0208 0.1227 0.5787
Entamoeba histolytica cysteine protease, putative 0.0208 0.1227 0.5787
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0176 0.0795
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Entamoeba histolytica cysteine protease, putative 0.0208 0.1227 0.5787
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0208 0.1227 0.2611
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0197 0.0898
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0088 0.0482 0.225
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.038 0.333
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0018 0.0046 0.008
Loa Loa (eye worm) hypothetical protein 0.0048 0.0232 0.048
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0482 0.225
Echinococcus granulosus expressed conserved protein 0.0185 0.1084 0.2305
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0063 0.033 0.0662
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0067 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0297 0.1779 0.8409
Brugia malayi nuclear receptor NHR-88 0.0018 0.0046 0.0098
Onchocerca volvulus 0.0049 0.024 0.11
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0235 0.0485
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0297 0.0619
Trypanosoma cruzi major cysteine proteinase, putative 0.0088 0.0482 0.099
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0146 0.102
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0049 0.0196
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0146 0.0847
Entamoeba histolytica cysteine protease, putative 0.0208 0.1227 0.5787
Giardia lamblia Cathepsin L precursor 0.0088 0.0482 0.2523
Schistosoma mansoni RAR-like nuclear receptor 0.0018 0.0046 0.008
Plasmodium vivax vivapain-2 0.0351 0.2114 1
Schistosoma mansoni hypothetical protein 0.0048 0.0232 0.048
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0182 0.0826
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0232 0.0497
Giardia lamblia Cathepsin L-like protease 0.0088 0.0482 0.2523
Leishmania major cathepsin L-like protease 0.0351 0.2114 1
Brugia malayi Papain family cysteine protease containing protein 0.0088 0.0482 0.1031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0027 0.0091
Onchocerca volvulus 0.005 0.0248 0.1137
Entamoeba histolytica cysteine protease, putative 0.0208 0.1227 0.5787
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.003 0.0105
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0208 0.1227 0.259
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0067 0.0278
Echinococcus multilocularis Niemann Pick C1 protein 0.0282 0.1683 0.1676
Echinococcus multilocularis cathepsin b 0.0765 0.4676 0.4672
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0319 0.2816
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0044 0.0171
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Brugia malayi protein C24B5.3 0.0012 0.0011 0.0023
Echinococcus granulosus chromobox protein 1 0.0071 0.0375 0.0785
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0049 0.0196
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0146 0.0656
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0088 0.0482 0.225
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0351 0.2114 1
Brugia malayi Cathepsin L-like precursor 0.0351 0.2114 0.4521
Plasmodium vivax vivapain-2 0.0351 0.2114 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0067 0.0143
Onchocerca volvulus 0.0012 0.0011 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0012 0.0012 0.0009
Entamoeba histolytica acyl-coA synthetase, putative 0.0072 0.038 0.1765
Onchocerca volvulus 0.0351 0.2114 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0067 0.0189
Loa Loa (eye worm) hypothetical protein 0.0014 0.0021 0.0028
Plasmodium falciparum serine repeat antigen 1 0.0088 0.0482 0.225
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0303 0.1401
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.0091 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0088 0.0482 0.225
Echinococcus multilocularis Niemann Pick C1 protein 0.0197 0.1158 0.1151
Trypanosoma brucei hypothetical protein, conserved 0.0216 0.1275 0.599
Brugia malayi Glycosyl hydrolases family 31 protein 0.0165 0.0962 0.2056
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0091 0.0255
Schistosoma mansoni hypothetical protein 0.0037 0.0163 0.0331
Onchocerca volvulus 0.0025 0.0091 0.0393
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0088 0.0482 0.1031
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0146 0.0296
Giardia lamblia Cathepsin L precursor 0.0088 0.0482 0.2523
Echinococcus multilocularis pyruvate kinase 0.0017 0.0044 0.0036
Brugia malayi chromobox protein homolog 3 0.004 0.0182 0.039
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0268 0.141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0018 0.0046 0.008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0046 0.0098
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0151 0.0871 0.1849
Entamoeba histolytica cysteine protease, putative 0.0208 0.1227 0.5787
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0018 0.0046 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0046 0.0098
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Onchocerca volvulus 0.0021 0.0067 0.0278
Giardia lamblia Cathepsin L precursor 0.0088 0.0482 0.2523
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0164 0.0307
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Echinococcus granulosus cpg binding protein 0.0031 0.0129 0.0259
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0067 0.0217
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0164 0.0351
Trypanosoma cruzi cysteine peptidase, putative 0.0351 0.2114 0.4496
Giardia lamblia Encystation-specific protease 0.0088 0.0482 0.2523
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0146 0.0656
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0208 0.1227 0.5787
Schistosoma mansoni alpha glucosidase 0.0037 0.0164 0.0334
Onchocerca volvulus Protein patched homolog 0.0012 0.0011 0.0011
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0146 0.0598
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0067 0.0217
Echinococcus granulosus endonuclease exonuclease phosphatase 0.019 0.1112 0.2365
Loa Loa (eye worm) hypothetical protein 0.0197 0.1158 0.2464
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0276 0.059
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.008
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0067 0.0189
Plasmodium vivax serine-repeat antigen (SERA) 0.0088 0.0482 0.225
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0351 0.2114 1
Entamoeba histolytica hypothetical protein 0.0037 0.0163 0.0734
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0088 0.0482 0.225
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0319 0.0311
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.033 0.0662
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.025 0.2098
Schistosoma mansoni pyruvate kinase 0.0017 0.0044 0.0077
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0232 0.0224
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0088 0.0482 0.225
Echinococcus granulosus pyruvate kinase 0.0034 0.0146 0.0296
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0088 0.0482 0.1015
Echinococcus multilocularis pyruvate kinase 0.0034 0.0146 0.0138
Loa Loa (eye worm) hypothetical protein 0.0088 0.0482 0.1015
Brugia malayi nuclear hormone receptor 0.0018 0.0046 0.0098
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.025 0.2098
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0235 0.0227
Loa Loa (eye worm) hypothetical protein 0.012 0.0681 0.1442
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0146 0.0269
Brugia malayi cathepsin L precursor 0.0088 0.0482 0.1031
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0021 0.0062
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0146 0.0313
Brugia malayi AMP-binding enzyme family protein 0.0072 0.038 0.0812
Entamoeba histolytica hypothetical protein 0.0088 0.0482 0.225
Schistosoma mansoni pyruvate kinase 0.0034 0.0146 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0088 0.0482 0.225
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.038 0.333
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0164 0.0739
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.008
Leishmania major cathepsin L-like protease 0.0351 0.2114 1
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0067 0.0143
Entamoeba histolytica cysteine protease, putative 0.0208 0.1227 0.5787
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0319 0.2677
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0164 0.0739
Loa Loa (eye worm) hypothetical protein 0.0088 0.0482 0.1015
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0091 0.0255
Onchocerca volvulus 0.0031 0.0129 0.0574
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0067 0.0278
Plasmodium falciparum serine repeat antigen 2 0.0088 0.0482 0.225
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.011 0.0485
Schistosoma mansoni hypothetical protein 0.0082 0.0442 0.0929
Onchocerca volvulus Cathepsin L homolog 0.0351 0.2114 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0765 0.4676 1
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0088 0.0482 0.1015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0088 0.0482 0.225
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0351 0.2114 0.2108
Loa Loa (eye worm) hypothetical protein 0.0048 0.0235 0.0485
Loa Loa (eye worm) acetyltransferase 0.0143 0.0823 0.1746
Echinococcus multilocularis protein dispatched 1 0.0097 0.0535 0.0527
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0088 0.0482 0.225
Echinococcus multilocularis pyruvate kinase 0.0027 0.0102 0.0094
Onchocerca volvulus 0.0012 0.0011 0.0011
Onchocerca volvulus Bile acid receptor homolog 0.0018 0.0046 0.0178
Brugia malayi cathepsin F-like cysteine proteinase 0.012 0.0681 0.1457
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.038 0.1714
Loa Loa (eye worm) cysteine protease 0.0351 0.2114 0.4511
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0297 0.2453
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0088 0.0482 0.2523
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0049 0.0196
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0046 0.0098
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0008 0.0018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.008
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0182 0.0826
Brugia malayi AMP-binding enzyme family protein 0.0072 0.038 0.0812
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0765 0.4676 1
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0146 0.0269
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0049 0.0196
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0067 0.0125
Brugia malayi cathepsin Z-like cysteine proteinase 0.0088 0.0482 0.1031
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0088 0.0482 0.1015
Trypanosoma cruzi cysteine proteinase, putative 0.0208 0.1227 0.259
Loa Loa (eye worm) hypothetical protein 0.0031 0.0129 0.0259
Brugia malayi acetyltransferase, GNAT family protein 0.0143 0.0823 0.1761
Loa Loa (eye worm) hypothetical protein 0.0088 0.0482 0.1015
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.0091 0.0439
Onchocerca volvulus Cathepsin L homolog 0.0088 0.0482 0.225
Schistosoma mansoni niemann-pick C1 (NPC1) 0.02 0.1177 0.2504
Echinococcus granulosus cathepsin L 0.0208 0.1227 0.2611
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0165 0.0962 0.2042
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0018 0.0046 0.008
Entamoeba histolytica cysteine protease, putative 0.0208 0.1227 0.5787
Plasmodium falciparum serine repeat antigen 7 0.0088 0.0482 0.225
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0067 0.0125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0088 0.0482 0.225
Brugia malayi Patched protein homolog 1 0.0012 0.0011 0.0023
Giardia lamblia Cathepsin B precursor 0.0297 0.1779 1
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.011 0.0485
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0067 0.0217
Loa Loa (eye worm) patched family protein 0.0012 0.0011 0.0005
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0461 0.097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2114 1
Brugia malayi Cathepsin L-like precursor 0.0231 0.1369 0.2928
Plasmodium falciparum lipid/sterol:H+ symporter 0.0012 0.0011 0.0011
Brugia malayi cathepsin L-like precursor 0.0231 0.1369 0.2928
Echinococcus granulosus cathepsin b 0.0765 0.4676 1
Loa Loa (eye worm) hypothetical protein 0.0151 0.0871 0.1849
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0018 0.0046 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2114 1
Plasmodium falciparum serine repeat antigen 9 0.0088 0.0482 0.225
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0216 0.0446
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0164 0.0739
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0088 0.0482 0.225
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0143 0.0823 0.1746
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.025 0.2098
Echinococcus granulosus pyruvate kinase 0.0017 0.0044 0.0077
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Giardia lamblia Cathepsin B precursor 0.0297 0.1779 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0018 0.0046 0.0037
Schistosoma mansoni coup transcription factor 0.0018 0.0046 0.008
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.024 0.0513
Loa Loa (eye worm) hypothetical protein 0.0104 0.0579 0.1222
Brugia malayi cathepsin F-like cysteine proteinase 0.0088 0.0482 0.1031
Entamoeba histolytica cysteine proteinase, putative 0.0208 0.1227 0.5787
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0163 0.0331
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0232 0.048
Echinococcus granulosus tumor protein p63 0.0343 0.2062 0.44
Giardia lamblia Cathepsin B precursor 0.0088 0.0482 0.2523
Echinococcus granulosus cysteine protease 0.0208 0.1227 0.2611
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0143 0.0823 0.0816
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Loa Loa (eye worm) hypothetical protein 0.0088 0.0482 0.1015
Echinococcus multilocularis tumor protein p63 0.0343 0.2062 0.2056
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0216 0.0446
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0088 0.0482 0.1015
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0319 0.0665
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0173 0.1007 0.4744
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0088 0.0482 0.225
Onchocerca volvulus 0.0096 0.0529 0.2474
Echinococcus multilocularis cathepsin L 0.0208 0.1227 0.122
Brugia malayi Steroid receptor seven-up type 2 0.0018 0.0046 0.0098
Brugia malayi hypothetical protein 0.0012 0.0011 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0208 0.1227 0.576
Entamoeba histolytica cysteine protease, putative 0.0088 0.0482 0.225
Loa Loa (eye worm) MBCTL1 0.0055 0.0276 0.0574
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0164 0.0307
Entamoeba histolytica cysteine proteinase, putative 0.0351 0.2114 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0173 0.1007 0.5
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Trypanosoma cruzi cysteine peptidase, putative 0.0351 0.2114 0.4496
Loa Loa (eye worm) hypothetical protein 0.0088 0.0482 0.1015
Schistosoma mansoni hypothetical protein 0.0049 0.024 0.0496
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Onchocerca volvulus 0.0018 0.0046 0.0178
Giardia lamblia Pyruvate kinase 0.0034 0.0146 0.0589
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0232 0.048
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0235 0.1394 0.2968
Onchocerca volvulus 0.0021 0.0067 0.0278
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0146 0.0296
Leishmania major hypothetical protein, conserved 0.0216 0.1275 0.599
Echinococcus multilocularis ecdysone induced protein 78C 0.0018 0.0046 0.0037
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0067 0.0143
Leishmania major cathepsin L-like protease 0.0351 0.2114 1
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0008 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0088 0.0482 0.225
Brugia malayi Papain family cysteine protease containing protein 0.0088 0.0482 0.1031
Echinococcus granulosus ecdysone induced protein 78C 0.0018 0.0046 0.008
Onchocerca volvulus 0.0231 0.1369 0.6463
Schistosoma mansoni hypothetical protein 0.0048 0.0232 0.048
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.038 0.1714
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0067 0.0189
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0208 0.1227 0.2611
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Trypanosoma cruzi cysteine peptidase, putative 0.012 0.0681 0.1418
Brugia malayi hypothetical protein 0.0037 0.0163 0.0348
Loa Loa (eye worm) hypothetical protein 0.0021 0.0067 0.0125
Echinococcus granulosus histone acetyltransferase KAT2B 0.0139 0.0798 0.1693
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0018 0.0046 0.0037
Echinococcus multilocularis chromobox protein 1 0.0071 0.0375 0.0367
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0067 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0208 0.1227 0.5787
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0765 0.4676 1
Echinococcus multilocularis cpg binding protein 0.0031 0.0129 0.0121
Plasmodium falciparum phosphoglycerate kinase 0.0173 0.1007 0.4744
Schistosoma mansoni cathepsin B (C01 family) 0.0088 0.0482 0.1015
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0146 0.0656
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0765 0.4676 1
Plasmodium falciparum serine repeat antigen 6 0.0088 0.0482 0.225
Brugia malayi mbt repeat family protein 0.0048 0.0235 0.0502
Echinococcus granulosus cathepsin l cysteine peptidase 0.0351 0.2114 0.4511
Schistosoma mansoni microtubule-associated protein tau 0.07 0.4278 0.9147
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.025 0.2098
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0146 0.0656
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0235 0.1076
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0351 0.2114 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0319 0.142
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0018 0.0046 0.0098
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0088 0.0482 0.225
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0088 0.0482 0.225
Echinococcus multilocularis survival motor neuron protein 1 0.024 0.1424 0.1417
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0046 0.0098
Loa Loa (eye worm) hypothetical protein 0.0231 0.1369 0.2916
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0375 0.1741
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0067 0.0143
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0173 0.1007 1
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0067 0.0189
Brugia malayi Phosphoglycerate kinase 0.0173 0.1007 0.2154
Leishmania major phosphoglycerate kinase B, cytosolic 0.0173 0.1007 0.4711
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0146 0.0656
Plasmodium falciparum serine repeat antigen 8 0.0088 0.0482 0.225
Echinococcus granulosus cathepsin L cysteine protease 0.0208 0.1227 0.2611
Leishmania major cathepsin L-like protease 0.0351 0.2114 1
Entamoeba histolytica cysteine protease, putative 0.0351 0.2114 1
Echinococcus multilocularis cysteine protease 0.0351 0.2114 0.2108
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0091 0.0149
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0067 0.0189
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0351 0.2114 1
Brugia malayi Cathepsin L-like precursor 0.0351 0.2114 0.4521
Leishmania major cathepsin L-like protease 0.0351 0.2114 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0018 0.0046 0.0037
Leishmania major cathepsin L-like protease 0.0351 0.2114 1
Brugia malayi Niemann-Pick C1 protein precursor 0.0197 0.1158 0.2477
Entamoeba histolytica cysteine protease, putative 0.0088 0.0482 0.225
Brugia malayi Patched family protein 0.0012 0.0011 0.0023
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0018 0.0046 0.0037
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0088 0.0482 0.225
Trypanosoma brucei phosphoglycerate kinase 0.0173 0.1007 0.4711
Giardia lamblia Cathepsin B precursor 0.0088 0.0482 0.2523
Giardia lamblia Hypothetical protein 0.0088 0.0482 0.2523
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0164 0.0156
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0164 0.0739
Echinococcus granulosus pyruvate kinase 0.0017 0.0044 0.0077
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0232 0.0497
Schistosoma mansoni cathepsin F (C01 family) 0.0351 0.2114 0.4511
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0088 0.0482 0.1015
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0088 0.0482 0.225
Loa Loa (eye worm) hypothetical protein 0.0053 0.0268 0.0556
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0164 0.0682
Brugia malayi hypothetical protein 0.024 0.1424 0.3046
Onchocerca volvulus 0.0012 0.0012 0.0019
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.038 0.3456
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0005

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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