Detailed information for compound 1213711

Basic information

Technical information
  • TDR Targets ID: 1213711
  • Name: (3,6,7-triacetyloxy-9-oxoxanthen-2-yl) acetat e
  • MW: 428.346 | Formula: C21H16O10
  • H donors: 0 H acceptors: 5 LogP: 1.97 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)Oc1cc2c(cc1OC(=O)C)oc1c(c2=O)cc(c(c1)OC(=O)C)OC(=O)C
  • InChi: 1S/C21H16O10/c1-9(22)27-17-5-13-15(7-19(17)29-11(3)24)31-16-8-20(30-12(4)25)18(28-10(2)23)6-14(16)21(13)26/h5-8H,1-4H3
  • InChiKey: GVZVCPHPBNOQLD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (3,6,7-triacetoxy-9-oxo-xanthen-2-yl) acetate
  • acetic acid (3,6,7-triacetoxy-9-oxo-2-xanthenyl) ester
  • acetic acid (3,6,7-triacetoxy-9-keto-xanthen-2-yl) ester
  • (3,6,7-triacetyloxy-9-oxo-xanthen-2-yl) ethanoate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0087 0.0112
Trichomonas vaginalis glucose transporter, putative 0.003 0.0201 0.0825
Echinococcus multilocularis pyruvate kinase 0.0034 0.0251 0.0287
Toxoplasma gondii transporter, major facilitator family protein 0.003 0.0201 0.0305
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0079 0.0747 0.2212
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0003 0.0005
Onchocerca volvulus 0.003 0.0201 0.0107
Plasmodium vivax hypothetical protein, conserved 0.0113 0.1132 0.1132
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0064 0.0582 0.0749
Schistosoma mansoni zinc finger protein 0.0015 0.0033 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0087 0.0257
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0359 0.1064
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0201 0.0825
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0133 0.1787
Chlamydia trachomatis proline--tRNA ligase 0.0023 0.0119 0.1926
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0526 0.0678
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0087 0.045
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0566 0.11
Leishmania major glucose transporter/membrane transporter D2, putative 0.0066 0.0606 0.1795
Brugia malayi hypothetical protein 0.0017 0.0055 0.0107
Brugia malayi Pyruvate kinase, muscle isozyme 0.0067 0.0616 0.1197
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0052 0.0102
Echinococcus granulosus General substrate transporter 0.0183 0.1918 0.2468
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0065 0.0597 0.0597
Schistosoma mansoni hypothetical protein 0.0107 0.1064 0.137
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0485 0.0942
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0597 0.0682
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0079 0.0747 0.3059
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0616 0.1197
Toxoplasma gondii sugar transporter ST1 0.003 0.0201 0.0305
Echinococcus granulosus solute carrier family 22 0.003 0.0201 0.0259
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0132 0.0169
Mycobacterium ulcerans pyruvate kinase 0.0067 0.0616 0.32
Brugia malayi beta-lactamase family protein 0.0113 0.1132 0.2199
Leishmania major protein kinase, putative 0.0065 0.0597 0.1768
Brugia malayi jmjC domain containing protein 0.0016 0.0042 0.0081
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0201 0.0391
Trichomonas vaginalis pyruvate kinase, putative 0.0067 0.0616 0.2524
Echinococcus multilocularis solute carrier family 22 0.003 0.0201 0.023
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.0818 0.0934
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0052 0.0155
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0159 0.0241
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.1408 0.1812
Onchocerca volvulus 0.003 0.0201 0.0107
Schistosoma mansoni hypothetical protein 0.0419 0.4557 0.5866
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0297 0.0382
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0566 0.0729
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0606 0.1795
Plasmodium falciparum thioredoxin reductase 0.0048 0.0404 0.0404
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0075 0.0701 0.2075
Brugia malayi Sugar transporter family protein 0.0213 0.2253 0.4377
Trypanosoma brucei glucose transporter, putative 0.0066 0.0606 0.1795
Schistosoma mansoni hypothetical protein 0.0015 0.0033 0.0043
Mycobacterium tuberculosis Conserved protein 0.0113 0.1132 0.1423
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0148 0.1527 0.4523
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0201 0.0391
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0526 0.0678
Echinococcus granulosus beta LACTamase domain containing family member 0.0113 0.1132 0.1457
Echinococcus granulosus solute carrier family 22 0.003 0.0201 0.0259
Trypanosoma brucei trypanothione reductase 0.0048 0.0404 0.1197
Mycobacterium ulcerans lipase LipD 0.0113 0.1132 0.5881
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0042 0.0063
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0052 0.0272
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0132 0.0169
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0213 0.2253 0.2574
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0052 0.0155
Schistosoma mansoni inositol monophosphatase 0.0079 0.0747 0.0961
Onchocerca volvulus 0.003 0.0201 0.0107
Toxoplasma gondii aldehyde dehydrogenase 0.0184 0.1925 0.2912
Trypanosoma brucei glucose transporter 1E 0.0066 0.0606 0.1795
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0065 0.0597 0.1159
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0052 0.0155
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0033 0.0063
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0201 0.0391
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0196 0.0253
Trypanosoma cruzi sugar transporter, putative 0.003 0.0201 0.0596
Echinococcus multilocularis dna polymerase eta 0.002 0.0087 0.0099
Onchocerca volvulus 0.003 0.0201 0.0107
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0079 0.0747 0.2212
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0065 0.0597 0.0768
Brugia malayi Pre-SET motif family protein 0.0202 0.2129 0.4136
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0597 0.0768
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0052 0.0155
Trypanosoma brucei ISWI complex protein 0.0015 0.0033 0.0099
Onchocerca volvulus 0.003 0.0196 0.0086
Entamoeba histolytica protein kinase, putative 0.0065 0.0597 0.5609
Leishmania major lysyl-tRNA synthetase, putative 0.0048 0.0399 0.1181
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0079 0.0747 0.3879
Onchocerca volvulus 0.0085 0.0818 0.2831
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0606 0.2484
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.1408 0.1608
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0344 0.3724 0.3724
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0087 0.0257
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0383 0.0494
Loa Loa (eye worm) sugar transporter 0.0213 0.2253 0.4377
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0031
Toxoplasma gondii hypothetical protein 0.0051 0.0432 0.0653
Schistosoma mansoni intermediate filament proteins 0.0028 0.0177 0.0228
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0064 0.0582 0.1131
Echinococcus multilocularis zinc finger protein 0.0021 0.0099 0.0113
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0539 0.0616
Loa Loa (eye worm) hypothetical protein 0.0055 0.0485 0.0942
Mycobacterium tuberculosis Probable esterase LipL 0.0113 0.1132 0.1423
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.0818 0.1589
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0213 0.2253 0.2574
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0016 0.0021
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0079 0.0747 0.7018
Treponema pallidum NADH oxidase 0.0017 0.0052 0.1762
Entamoeba histolytica protein kinase, putative 0.0065 0.0597 0.5609
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0606 0.1795
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0087 0.0168
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0052 0.0155
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0606 0.1795
Brugia malayi pyruvate kinase, muscle isozyme 0.0014 0.0024 0.0046
Schistosoma mansoni hypothetical protein 0.002 0.0092 0.0118
Plasmodium falciparum hexose transporter 0.0213 0.2253 0.2253
Toxoplasma gondii protein kinase, putative 0.0602 0.6612 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0087 0.0257
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0087 0.0257
Loa Loa (eye worm) hypothetical protein 0.0048 0.0399 0.0774
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0048 0.0399 0.1181
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Schistosoma mansoni sugar transporter 0.003 0.0201 0.0259
Echinococcus granulosus GPCR family 2 0.0017 0.0062 0.0079
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0087 0.0355
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.1132 0.3353
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0297 0.0879
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0052 0.0067
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0092 0.0178
Schistosoma mansoni lamin 0.0028 0.0177 0.0228
Brugia malayi beta-lactamase 0.0113 0.1132 0.2199
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0052 0.0155
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0159 0.0471
Brugia malayi beta-lactamase family protein 0.0113 0.1132 0.2199
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0201 0.0825
Loa Loa (eye worm) follicle stimulating hormone receptor 0.026 0.2773 0.5387
Mycobacterium ulcerans aldehyde dehydrogenase 0.0184 0.1925 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0526 0.0601
Onchocerca volvulus 0.003 0.0201 0.0107
Brugia malayi follicle stimulating hormone receptor 0.026 0.2773 0.5387
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.011 0.1094 0.1375
Plasmodium vivax lysine--tRNA ligase, putative 0.0048 0.0399 0.0399
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0606 0.1795
Echinococcus granulosus geminin 0.0349 0.3771 0.4855
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0404 0.052
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0148 0.1527 0.4523
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0122 0.1231 0.1547
Loa Loa (eye worm) hypothetical protein 0.0027 0.0171 0.0333
Echinococcus granulosus lysyl tRNA synthetase 0.0048 0.0399 0.0513
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0133 0.0693
Echinococcus multilocularis GPCR, family 2 0.0017 0.0062 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0087 0.0257
Schistosoma mansoni aldehyde dehydrogenase 0.0184 0.1925 0.2478
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.1132 0.4638
Echinococcus multilocularis solute carrier family 22 0.003 0.0201 0.023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0081
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Loa Loa (eye worm) hypothetical protein 0.0052 0.0448 0.087
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.011 0.1094 0.1375
Leishmania major DNA polymerase eta, putative 0.002 0.0087 0.0257
Brugia malayi lysyl-tRNA synthetase 0.0048 0.0399 0.0774
Trichomonas vaginalis CAMK family protein kinase 0.0065 0.0597 0.2445
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0052 0.0272
Brugia malayi Cam kinase protein 1 0.0065 0.0597 0.1159
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0042 0.0048
Loa Loa (eye worm) hypothetical protein 0.0069 0.0641 0.1245
Schistosoma mansoni glucose transport protein 0.0213 0.2253 0.2901
Echinococcus granulosus pyruvate kinase 0.0067 0.0616 0.0793
Echinococcus multilocularis lysyl tRNA synthetase 0.0048 0.0399 0.0455
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0213 0.2253 0.2901
Plasmodium falciparum protein kinase 7 0.0602 0.6612 0.6612
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0794 0.8756 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0052 0.006
Toxoplasma gondii facilitative glucose transporter GT1 0.0213 0.2253 0.3408
Trypanosoma brucei sugar transporter, putative 0.003 0.0201 0.0596
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0184 0.1925 0.5702
Loa Loa (eye worm) hypothetical protein 0.0145 0.1485 0.2885
Onchocerca volvulus 0.003 0.0201 0.0107
Schistosoma mansoni cpg binding protein 0.0029 0.0195 0.0251
Plasmodium falciparum pyruvate kinase 2 0.0034 0.0251 0.0251
Echinococcus granulosus solute carrier family 22 0.003 0.0201 0.0259
Loa Loa (eye worm) hypothetical protein 0.0145 0.1485 0.2885
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.003 0.0201 0.0259
Schistosoma mansoni pyruvate kinase 0.0067 0.0616 0.0793
Trypanosoma brucei glucose transporter, putative 0.0066 0.0606 0.1795
Schistosoma mansoni hypothetical protein 0.0096 0.0943 0.1214
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0052 0.0079
Trypanosoma cruzi hexose transporter, putative 0.003 0.0201 0.0596
Loa Loa (eye worm) hypothetical protein 0.0017 0.0062 0.012
Onchocerca volvulus 0.003 0.0201 0.0107
Echinococcus granulosus Sugar transporter ERD6 protein 0.003 0.0201 0.0259
Echinococcus multilocularis Sugar transporter ERD6 protein 0.003 0.0201 0.023
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.007 0.0654 0.0822
Trypanosoma brucei glucose transporter, putative 0.0066 0.0606 0.1795
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0148 0.1527 0.4523
Onchocerca volvulus 0.003 0.0201 0.0107
Toxoplasma gondii ABC1 family protein 0.0113 0.1132 0.1712
Trichomonas vaginalis sugar transport protein, putative 0.003 0.0201 0.0825
Brugia malayi pyruvate kinase 0.0014 0.0024 0.0046
Schistosoma mansoni survival motor neuron protein 0.0096 0.0943 0.1214
Echinococcus granulosus lamin dm0 0.0028 0.0177 0.0228
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.026 0.0296
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0052 0.07
Mycobacterium leprae Probable lipase LipE 0.0113 0.1132 0.9195
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0122 0.1231 0.1547
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0132 0.015
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0168
Schistosoma mansoni sugar transporter 0.003 0.0201 0.0259
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0087 0.0257
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0313 0.3377 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0081
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0113 0.1132 0.1423
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0065 0.0597 0.0903
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0313 0.3377 1
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0159 0.0471
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0113 0.1132 0.2199
Echinococcus multilocularis pyruvate kinase 0.0067 0.0616 0.0704
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0042 0.0124
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.1408 0.1812
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Trypanosoma brucei glucose transporter, putative 0.0066 0.0606 0.1795
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0087 0.0257
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0359 0.1064
Loa Loa (eye worm) glutathione reductase 0.0048 0.0404 0.0785
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Schistosoma mansoni DNA polymerase eta 0.002 0.0087 0.0112
Toxoplasma gondii thioredoxin reductase 0.0048 0.0404 0.0611
Toxoplasma gondii pyruvate kinase PyK1 0.0067 0.0616 0.0932
Mycobacterium tuberculosis Probable hydrolase 0.0113 0.1132 0.1423
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0184 0.1925 0.2419
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.003 0.0201 0.0201
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0053 0.0068
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0064 0.0582 0.4727
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0064 0.0582 0.1131
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0087 0.0257
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0016 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0213 0.2253 0.9232
Giardia lamblia Pyruvate kinase 0.0034 0.0251 0.4072
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0616 0.1197
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.1132 0.4638
Mycobacterium ulcerans sugar transporter 0.003 0.0201 0.1046
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0042 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0196 0.0253
Mycobacterium ulcerans esterase/lipase LipP 0.0113 0.1132 0.5881
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0122 0.1231 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0052 0.0052
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0289 0.0562
Schistosoma mansoni bromodomain containing protein 0.0064 0.0578 0.0744
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0052 0.0155
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0184 0.1925 0.2478
Schistosoma mansoni ap endonuclease 0.0038 0.0297 0.0382
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0087 0.0355
Onchocerca volvulus Putative transporter 0.003 0.0201 0.0107
Trypanosoma brucei pyruvate kinase 1 0.0067 0.0616 0.1825
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0313 0.3377 1
Trypanosoma brucei pyruvate kinase 1, putative 0.0067 0.0616 0.1825
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0082 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0606 0.2484
Onchocerca volvulus 0.003 0.0201 0.0107
Loa Loa (eye worm) hypothetical protein 0.0113 0.1132 0.2199
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0042 0.0054
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0042 0.0054
Giardia lamblia Hexose transporter 0.003 0.0201 0.3269
Brugia malayi intermediate filament protein 0.0028 0.0177 0.0344
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0087 0.0109
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0297 0.0297
Echinococcus multilocularis solute carrier family 22 0.003 0.0201 0.023
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0597 0.0768
Trichomonas vaginalis pyruvate kinase, putative 0.0067 0.0616 0.2524
Schistosoma mansoni hypothetical protein 0.0017 0.0062 0.0079
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0052 0.0155
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0052 0.0155
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0318 0.2585
Echinococcus granulosus neuropeptide receptor A26 0.0515 0.5631 0.7248
Loa Loa (eye worm) pyruvate kinase-PB 0.0047 0.0389 0.0756
Onchocerca volvulus 0.003 0.0201 0.0107
Schistosoma mansoni hypothetical protein 0.0017 0.0062 0.0079
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0606 0.2484
Echinococcus granulosus microtubule associated protein 2 0.0706 0.7769 1
Schistosoma mansoni sugar transporter 0.003 0.0201 0.0259
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0943 0.1832
Echinococcus granulosus zinc finger protein 0.0021 0.0099 0.0128
Leishmania major pyruvate kinase 0.0067 0.0616 0.1825
Brugia malayi Bromodomain containing protein 0.0037 0.0286 0.0555
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0042 0.0048
Entamoeba histolytica pyruvate kinase, putative 0.0047 0.0389 0.3657
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0048 0.0399 0.1633
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0485 0.0942
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0052 0.0079
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0138 0.1408 0.2734
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0023 0.0119 0.0617
Mycobacterium ulcerans beta-lactamase 0.0113 0.1132 0.5881
Mycobacterium ulcerans aldehyde dehydrogenase 0.0184 0.1925 1
Trypanosoma cruzi hexose transporter, putative 0.0036 0.027 0.0801
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0297 0.2789
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0177 0.0344
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0606 0.1795
Trichomonas vaginalis inositol monophosphatase, putative 0.0079 0.0747 0.3059
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0003 0.0005
Echinococcus multilocularis calcium dependent protein kinase 0.0061 0.0552 0.063
Echinococcus granulosus lysine specific demethylase 5A 0.0063 0.0566 0.0729
Brugia malayi Thioredoxin reductase 0.0048 0.0404 0.0785
Schistosoma mansoni glucose transport protein 0.0213 0.2253 0.2901
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.1408 0.1608
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0133 0.0395
Loa Loa (eye worm) hypothetical protein 0.0028 0.0177 0.0344
Giardia lamblia Lysyl-tRNA synthetase 0.0048 0.0399 0.647
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0087 0.0257
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0087 0.0257
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0616 0.1197
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0201 0.0391
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0087 0.0112
Loa Loa (eye worm) sugar transporter 0.003 0.0201 0.0391
Echinococcus multilocularis dnaJ subfamily B 0.0419 0.4557 0.5204
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0065 0.0597 0.0903
Brugia malayi hypothetical protein 0.0107 0.1064 0.2067
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0213 0.2253 0.2901
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0064 0.0582 0.0665
Schistosoma mansoni sugar transporter 0.003 0.0201 0.0259
Plasmodium vivax JmjC domain containing protein 0.0016 0.0042 0.0042
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.1132 0.4638
Trypanosoma brucei unspecified product 0.0014 0.0018 0.0054
Loa Loa (eye worm) hypothetical protein 0.0046 0.0383 0.0745
Loa Loa (eye worm) beta-lactamase 0.0113 0.1132 0.2199
Plasmodium vivax glutathione reductase, putative 0.0048 0.0404 0.0404
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.1132 0.1457
Schistosoma mansoni ap endonuclease 0.0038 0.0297 0.0382
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0042 0.0054
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0133 0.4498
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0201 0.0825
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.002
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0065 0.0597 0.0597
Chlamydia trachomatis pyruvate kinase 0.0067 0.0616 1
Plasmodium vivax sugar transporter, putative 0.003 0.0201 0.0201
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0033 0.0063
Entamoeba histolytica hypothetical protein 0.0107 0.1064 1
Echinococcus multilocularis geminin 0.0349 0.3771 0.4307
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0042 0.0054
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0297 0.1216
Loa Loa (eye worm) hypothetical protein 0.0067 0.0616 0.1197
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Onchocerca volvulus 0.0096 0.0943 0.3384
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0087 0.0109
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0062 0.012
Echinococcus granulosus intermediate filament protein 0.0028 0.0177 0.0228
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0087 0.0168
Echinococcus multilocularis cpg binding protein 0.0033 0.0235 0.0268
Trypanosoma brucei hypothetical protein, conserved 0.0113 0.1132 0.3353
Brugia malayi hypothetical protein 0.003 0.0201 0.0391
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0467 0.1384
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0107 0.1064 0.137
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0344 0.3724 0.5632
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0177 0.0228
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0075 0.0701 0.106
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Echinococcus granulosus muscleblind protein 0.0145 0.1485 0.1912
Leishmania major mitochondrial DNA polymerase beta 0.0313 0.3377 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0018 0.0054
Leishmania major hypothetical protein, conserved 0.0015 0.0033 0.0099
Giardia lamblia DINP protein human, muc B family 0.002 0.0087 0.1407
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0065 0.0597 0.1768
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0722 0.7957 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0052 0.0155
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0052 0.0052
Echinococcus granulosus solute carrier family 22 0.003 0.0201 0.0259
Brugia malayi CXXC zinc finger family protein 0.0029 0.0195 0.0379
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0213 0.2253 0.2574
Trichomonas vaginalis myo-inositol transporter, putative 0.003 0.0201 0.0825
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0052 0.0066
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Leishmania major glucose transporter, lmgt1 0.0066 0.0606 0.1795
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.007 0.0654 0.5315
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0597 0.0768
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0079 0.0747 0.2212
Trypanosoma brucei unspecified product 0.002 0.0087 0.0257
Leishmania major myo-inositol/proton symporter (MIT) 0.003 0.0201 0.0596
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0087 0.0257
Echinococcus multilocularis synaptic vesicle 2 protein 0.003 0.0201 0.023
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0528 0.0798
Schistosoma mansoni hypothetical protein 0.0017 0.0062 0.0079
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.002 0.0093 0.018
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0087 0.0099
Brugia malayi Pre-SET motif family protein 0.003 0.0196 0.0382
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0053 0.0068
Leishmania major hypothetical protein, conserved 0.0016 0.0042 0.0124
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0052 0.0214
Brugia malayi glutathione reductase 0.0048 0.0404 0.0785
Mycobacterium tuberculosis Probable reductase 0.011 0.1094 0.1375
Mycobacterium tuberculosis Probable lipase LipD 0.0113 0.1132 0.1423
Brugia malayi Sugar transporter family protein 0.003 0.0201 0.0391
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0052 0.0849
Loa Loa (eye worm) hypothetical protein 0.0113 0.1132 0.2199
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0133 0.0202
Toxoplasma gondii pyruvate kinase PyKII 0.0034 0.0251 0.0379
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0177 0.0344
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0297 0.0576
Schistosoma mansoni hypothetical protein 0.0038 0.0289 0.0372
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0404 0.0785
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0177 0.0344
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Trichomonas vaginalis esterase, putative 0.0113 0.1132 0.4638
Onchocerca volvulus 0.0113 0.1132 0.4219
Mycobacterium leprae conserved hypothetical protein 0.0113 0.1132 0.9195
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.1132 0.1457
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0042 0.0054
Echinococcus multilocularis pyruvate kinase 0.0034 0.0251 0.0287
Toxoplasma gondii lysine-tRNA ligase 0.0048 0.0399 0.0603
Schistosoma mansoni glucose transport protein 0.0213 0.2253 0.2901
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0297 0.0879
Brugia malayi hypothetical protein 0.003 0.0201 0.0391
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0159 0.0471
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0159 0.0159
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Echinococcus multilocularis pyruvate kinase 0.0034 0.0251 0.0287
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0052 0.0155
Toxoplasma gondii sugar transporter ST2 0.003 0.0201 0.0305
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Trypanosoma brucei unspecified product 0.0014 0.0018 0.0054
Brugia malayi jmjC domain containing protein 0.0063 0.0566 0.11
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.1132 0.3353
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0042 0.0054
Schistosoma mansoni cpg binding protein 0.0033 0.0235 0.0302
Onchocerca volvulus 0.003 0.0201 0.0107
Plasmodium falciparum proline--tRNA ligase 0.0075 0.0701 0.0701
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0606 0.2484
Entamoeba histolytica hypothetical protein 0.0107 0.1064 1
Entamoeba histolytica hypothetical protein 0.0107 0.1064 1
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0052 0.0272
Brugia malayi major facilitator superfamily protein 0.003 0.0201 0.0391
Trypanosoma brucei glucose transporter 2A 0.0066 0.0606 0.1795
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.1408 0.1812
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0062 0.0079
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0195 0.0379
Brugia malayi hypothetical protein 0.003 0.0201 0.0391
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0042 0.0054
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Leishmania major hypothetical protein, conserved 0.003 0.0201 0.0596
Mycobacterium leprae Probable pyruvate kinase PykA 0.0067 0.0616 0.5004
Mycobacterium tuberculosis Probable lipase LipE 0.0113 0.1132 0.1423
Plasmodium falciparum calcium-dependent protein kinase 1 0.0065 0.0597 0.0597
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0052 0.0155
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0297 0.0879
Brugia malayi PHD-finger family protein 0.0026 0.0158 0.0306
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Trypanosoma cruzi ISWI complex protein 0.0015 0.0033 0.0099
Mycobacterium ulcerans aldehyde dehydrogenase 0.0184 0.1925 1
Brugia malayi Pyruvate kinase, M2 isozyme 0.0067 0.0616 0.1197
Loa Loa (eye worm) hypothetical protein 0.0043 0.0352 0.0684
Schistosoma mansoni protein kinase 0.0065 0.0597 0.0768
Loa Loa (eye worm) hypothetical protein 0.0064 0.0582 0.1131
Echinococcus granulosus dna polymerase kappa 0.002 0.0087 0.0112
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Echinococcus multilocularis lamin 0.0028 0.0177 0.0202
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0597 0.0682
Leishmania major pyruvate kinase 0.0067 0.0616 0.1825
Schistosoma mansoni glucose transporter 0.003 0.0201 0.0259
Trypanosoma cruzi ISWI complex protein 0.0015 0.0033 0.0099
Entamoeba histolytica hypothetical protein 0.0024 0.0133 0.1254
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0087 0.0257
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0133 0.0202
Echinococcus granulosus pyruvate kinase 0.0034 0.0251 0.0323
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0064 0.0582 0.2385
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0566 0.0729
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0616 0.194
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0113 0.1132 0.5881
Leishmania major glucose transporter, lmgt2 0.0066 0.0606 0.1795
Onchocerca volvulus 0.003 0.0201 0.0107
Plasmodium falciparum calcium-dependent protein kinase 2 0.0065 0.0597 0.0597
Giardia lamblia Pyruvate kinase 0.0067 0.0616 1
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0042 0.0124
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Entamoeba histolytica hypothetical protein 0.0107 0.1064 1
Mycobacterium tuberculosis Conserved protein 0.0113 0.1132 0.1423
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0213 0.2253 0.2901
Trypanosoma cruzi glucose transporter, putative 0.003 0.0201 0.0596
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0075 0.0701 0.2075
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.2129 0.4136
Brugia malayi jmjC domain containing protein 0.0016 0.0042 0.0081
Echinococcus granulosus calcium dependent protein kinase 0.0061 0.0552 0.071
Leishmania major hypothetical protein, conserved 0.0113 0.1132 0.3353
Echinococcus granulosus dnaJ subfamily B 0.0419 0.4557 0.5866
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0052 0.07
Plasmodium falciparum calcium-dependent protein kinase 4 0.0065 0.0597 0.0597
Schistosoma mansoni hypothetical protein 0.0349 0.3771 0.4855
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.1132 0.4638
Giardia lamblia Sugar-proton symporter 0.003 0.0201 0.3269
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0062 0.012
Onchocerca volvulus 0.0113 0.1132 0.4219
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.004 0.0318 0.04
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0404 0.0404
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0297 0.0297
Leishmania major DNA polymerase kappa, putative 0.002 0.0087 0.0257
Schistosoma mansoni pyruvate kinase 0.0034 0.0251 0.0323
Schistosoma mansoni inositol monophosphatase 0.0079 0.0747 0.0961
Treponema pallidum prolyl-tRNA synthetase 0.0023 0.0119 0.4
Plasmodium falciparum calcium-dependent protein kinase 5 0.0065 0.0597 0.0597
Loa Loa (eye worm) hypothetical protein 0.0113 0.1132 0.2199
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0597 0.0682
Echinococcus multilocularis beta LACTamase domain containing family member 0.0113 0.1132 0.1293
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0196 0.0297
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0087 0.0257
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0087 0.0257
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0138 0.1408 0.2734
Mycobacterium ulcerans hypothetical protein 0.0113 0.1132 0.5881
Plasmodium vivax SET domain protein, putative 0.003 0.0196 0.0196
Loa Loa (eye worm) pyruvate kinase 0.0014 0.0024 0.0046
Echinococcus multilocularis pyruvate kinase 0.0067 0.0616 0.0704
Plasmodium falciparum lysine--tRNA ligase 0.0048 0.0399 0.0399
Plasmodium vivax calcium-dependent protein kinase, putative 0.0065 0.0597 0.0597
Onchocerca volvulus 0.003 0.0201 0.0107
Plasmodium vivax proline--tRNA ligase, putative 0.0075 0.0701 0.0701
Echinococcus granulosus histone lysine methyltransferase setb 0.0046 0.0383 0.0494
Schistosoma mansoni zinc finger protein 0.0021 0.0099 0.0128
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0297 0.3974
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0297 0.0373
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Echinococcus granulosus pyruvate kinase 0.0034 0.0251 0.0323
Loa Loa (eye worm) hypothetical protein 0.0113 0.1132 0.2199
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0297 0.0879
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0606 0.1795
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.003 0.0201 0.0253
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0042 0.0081
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0042 0.0042
Plasmodium falciparum glutathione reductase 0.0048 0.0404 0.0404
Echinococcus multilocularis survival motor neuron protein 1 0.0472 0.5148 0.5879
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0701 0.2075
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.003 0.0201 0.1046
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0597 0.0682
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0087 0.0168
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0383 0.0494
Onchocerca volvulus 0.023 0.2441 1
Onchocerca volvulus 0.003 0.0201 0.0107
Echinococcus multilocularis lamin dm0 0.0028 0.0177 0.0202
Plasmodium falciparum calcium-dependent protein kinase 3 0.0065 0.0597 0.0597
Leishmania major glucose transporter, lmgt3 0.0066 0.0606 0.1795
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0062 0.007
Entamoeba histolytica hypothetical protein 0.0048 0.0399 0.3746
Echinococcus granulosus neuropeptide s receptor 0.0515 0.5631 0.7248
Schistosoma mansoni hypothetical protein 0.0349 0.3771 0.4855
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0213 0.2253 0.2901
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0539 0.0694
Echinococcus multilocularis General substrate transporter 0.0183 0.1918 0.219
Brugia malayi jmjC domain containing protein 0.0059 0.0526 0.1023
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Echinococcus granulosus pyruvate kinase 0.0067 0.0616 0.0793
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0399 0.0513
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Mycobacterium ulcerans hypothetical protein 0.0165 0.1715 0.8908
Brugia malayi hypothetical protein 0.0472 0.5148 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Plasmodium falciparum glutathione reductase 0.0017 0.0052 0.0052
Chlamydia trachomatis lysine--tRNA ligase 0.0048 0.0399 0.647
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0052 0.0155
Giardia lamblia Prolyl-tRNA synthetase 0.0064 0.0582 0.9446
Plasmodium vivax pyruvate kinase 2, putative 0.0034 0.0251 0.0251
Onchocerca volvulus 0.0029 0.0195 0.0079
Schistosoma mansoni transcription factor LCR-F1 0.0107 0.1064 0.137
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0606 0.2484
Brugia malayi hypothetical protein 0.0026 0.0159 0.0309
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0113 0.1132 0.1423
Loa Loa (eye worm) hypothetical protein 0.0472 0.5148 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.011 0.1094 0.1375
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0297 0.0576
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Schistosoma mansoni aldehyde dehydrogenase 0.0184 0.1925 0.2478
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0297 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0113 0.1132 0.2199
Loa Loa (eye worm) hypothetical protein 0.0038 0.0289 0.0562
Schistosoma mansoni protein kinase 0.0065 0.0597 0.0768
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0297 0.1541
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0064 0.0582 0.0749
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0201 0.0825
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0079 0.0747 0.2212
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.002
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0159 0.0159
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.1231 0.1547
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0062 0.007
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0087 0.0112
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0062 0.0079
Schistosoma mansoni pyruvate kinase 0.0067 0.0616 0.0793
Loa Loa (eye worm) hypothetical protein 0.0113 0.1132 0.2199
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0042 0.0048
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Schistosoma mansoni cpg binding protein 0.0033 0.0235 0.0302
Loa Loa (eye worm) hypothetical protein 0.0026 0.0159 0.0309
Onchocerca volvulus 0.003 0.0201 0.0107
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0087 0.0257
Trypanosoma cruzi pyruvate kinase 2, putative 0.0067 0.0616 0.1825
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0052 0.0155
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0046 0.0383 0.0438
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0087 0.045
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0701 0.2075
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0079 0.0747 0.1129
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0597 0.0768
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0087 0.0257
Schistosoma mansoni hypothetical protein 0.0017 0.0062 0.0079
Loa Loa (eye worm) hypothetical protein 0.0038 0.0286 0.0556
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.011 0.1094 0.1375
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Echinococcus multilocularis pyruvate kinase 0.0053 0.0458 0.0523
Trypanosoma brucei glucose transporter, putative 0.0066 0.0606 0.1795
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0042 0.0081
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0107 0.1064 0.1215
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0701 0.2075
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0133 0.0168
Loa Loa (eye worm) hypothetical protein 0.004 0.0312 0.0607
Plasmodium vivax pyruvate kinase, putative 0.0067 0.0616 0.0616
Plasmodium vivax hexose transporter 0.0213 0.2253 0.2253
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0079 0.0747 0.3059
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0087 0.0815
Loa Loa (eye worm) inositol-1 0.0079 0.0747 0.1451
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0606 0.2484
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0133 0.0133
Mycobacterium tuberculosis Conserved hypothetical protein 0.0165 0.1715 0.2155
Echinococcus granulosus dna polymerase eta 0.002 0.0087 0.0112
Plasmodium falciparum mitogen-activated protein kinase 2 0.0344 0.3724 0.3724
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0159 0.0159
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0067 0.0616 0.0774
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0297 0.0339
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Plasmodium vivax CDK-related protein kinase 6, putative 0.0905 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0018 0.0054
Echinococcus granulosus inositol monophosphatase 1 0.0079 0.0747 0.0961
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0064 0.0582 0.547
Echinococcus multilocularis neuropeptide receptor A26 0.0515 0.5631 0.6431
Echinococcus granulosus pyruvate kinase 0.0034 0.0251 0.0323
Trypanosoma brucei glucose transporter, putative 0.0066 0.0606 0.1795
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Mycobacterium tuberculosis Conserved protein 0.0113 0.1132 0.1423
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0133 0.0133
Schistosoma mansoni protein kinase 0.0065 0.0597 0.0768
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Trypanosoma cruzi hexose transporter 0.0066 0.0606 0.1795
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0087 0.0257
Leishmania major trypanothione reductase 0.0048 0.0404 0.1197
Trypanosoma brucei glucose transporter, putative 0.0066 0.0606 0.1795
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0399 0.2071
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0196 0.0224
Mycobacterium tuberculosis Probable dehydrogenase 0.011 0.1094 0.1375
Onchocerca volvulus 0.003 0.0201 0.0107
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0052 0.0155
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0042 0.0063
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.0818 0.1053
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0526 0.0601
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0606 0.2484
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0399 0.2071
Trypanosoma cruzi pyruvate kinase 2, putative 0.0067 0.0616 0.1825
Trypanosoma brucei glucose transporter, putative 0.0066 0.0606 0.1795
Brugia malayi major facilitator superfamily protein 0.003 0.0201 0.0391
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Brugia malayi jmjC domain containing protein 0.0016 0.0042 0.0081
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0079 0.0747 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0485 0.0942
Echinococcus granulosus survival motor neuron protein 1 0.0472 0.5148 0.6626
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0133 0.0693
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0048 0.0399 0.1181
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0065 0.0597 0.1159
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0087 0.0257
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0052 0.0052
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.1408 0.1812
Brugia malayi jmjC domain containing protein 0.0016 0.0042 0.0081
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0059 0.0115
Schistosoma mansoni microtubule-associated protein tau 0.0706 0.7769 1
Plasmodium falciparum pyruvate kinase 0.0067 0.0616 0.0616
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.003 0.0201 0.0253
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0213 0.2253 0.2574
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.1132 0.4638
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0133 0.0395
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Loa Loa (eye worm) hypothetical protein 0.0065 0.0597 0.1159
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0297 0.1216
Echinococcus multilocularis muscleblind protein 1 0.0145 0.1485 0.1696
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0042 0.0124
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0201 0.0391
Brugia malayi Inositol-1 0.0079 0.0747 0.1451
Mycobacterium ulcerans integral membrane transport protein 0.003 0.0201 0.1046
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0065 0.0597 0.0597
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0065 0.0597 0.0903
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0201 0.0825
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0052 0.0052
Echinococcus granulosus phd:f box containing protein 0.0016 0.0042 0.0054
Brugia malayi Muscleblind-like protein 0.0145 0.1485 0.2885
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0053 0.0068
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.003 0.0201 0.0596
Loa Loa (eye worm) hypothetical protein 0.0047 0.0389 0.0756
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0133 0.1084
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0087 0.0257
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0082 0.0093
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0048 0.0399 0.3238
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0184 0.1925 0.2199
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0052 0.0849
Schistosoma mansoni hypothetical protein 0.0213 0.2253 0.2901
Echinococcus granulosus lamin 0.0028 0.0177 0.0228
Echinococcus granulosus cpg binding protein 0.0033 0.0235 0.0302
Onchocerca volvulus 0.0113 0.1132 0.4219
Brugia malayi Sugar transporter family protein 0.003 0.0201 0.0391
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0087 0.0257
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0404 0.0462
Echinococcus multilocularis musashi 0.0028 0.0177 0.0202
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0065 0.0597 0.1159
Trichomonas vaginalis set domain proteins, putative 0.023 0.2441 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0318 0.04
Echinococcus multilocularis inositol monophosphatase 1 0.0079 0.0747 0.0853
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0052 0.0067
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.0818 0.1053
Echinococcus granulosus synaptic vesicle 2 protein 0.003 0.0201 0.0259
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0042 0.0333 0.1364
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0359 0.1064
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0616 0.194
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0359 0.1064
Schistosoma mansoni lamin 0.0028 0.0177 0.0228
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0064 0.0582 0.0749
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.026 0.0334
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0113 0.1132 0.1423
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0576 0.0742
Toxoplasma gondii exonuclease III APE 0.0038 0.0297 0.0449
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0616 0.194
Loa Loa (eye worm) hypothetical protein 0.0085 0.0818 0.1589
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.016 0.031
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0042 0.0081
Echinococcus multilocularis neuropeptide s receptor 0.0515 0.5631 0.6431
Loa Loa (eye worm) hypothetical protein 0.0064 0.0582 0.1131
Echinococcus multilocularis microtubule associated protein 2 0.0706 0.7769 0.8873
Loa Loa (eye worm) hypothetical protein 0.0113 0.1132 0.2199
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0042 0.0054
Brugia malayi Bromodomain containing protein 0.0075 0.0707 0.1373
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0399 0.0513
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.1408 0.1812
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0404 0.1197
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0052 0.0214
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0018 0.0054
Echinococcus multilocularis solute carrier family 22 0.003 0.0201 0.023
Echinococcus multilocularis dna polymerase kappa 0.002 0.0087 0.0099
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.003 0.0201 0.1046
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0053 0.006
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.011 0.1094 0.8887
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Toxoplasma gondii sugar transporter ST3 0.003 0.0201 0.0305
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0825
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0297 0.4816
Plasmodium falciparum thioredoxin reductase 0.0017 0.0052 0.0052
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0052 0.0155
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0133 0.2166
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0404 0.0508
Echinococcus multilocularis muscleblind protein 0.0145 0.1485 0.1696
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0391
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0052 0.0155
Leishmania major hypothetical protein, conserved 0.0026 0.0159 0.0471
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.003 0.0201 0.2697
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0062 0.012

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) < 1 % Inhibition of ACE at 100 uM ChEMBL. 1517742

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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