Detailed information for compound 1428305

Basic information

Technical information
  • TDR Targets ID: 1428305
  • Name: N-[(2-methoxyphenyl)methyl]-2-(oxolan-2-ylmet hylamino)acetamide; oxalic acid
  • MW: 368.382 | Formula: C17H24N2O7
  • H donors: 4 H acceptors: 5 LogP: -1.52 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C(=O)O.COc1ccccc1CNC(=O)CNCC1CCCO1
  • InChi: 1S/C15H22N2O3.C2H2O4/c1-19-14-7-3-2-5-12(14)9-17-15(18)11-16-10-13-6-4-8-20-13;3-1(4)2(5)6/h2-3,5,7,13,16H,4,6,8-11H2,1H3,(H,17,18);(H,3,4)(H,5,6)
  • InChiKey: WGSOHGSYHZTVCW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-[(2-methoxyphenyl)methyl]-2-(tetrahydrofuran-2-ylmethylamino)acetamide; oxalic acid
  • N-[(2-methoxyphenyl)methyl]-2-(2-tetrahydrofuranylmethylamino)acetamide; oxalic acid
  • N-(2-methoxybenzyl)-2-(tetrahydrofurfurylamino)acetamide; oxalic acid
  • ethanedioic acid; N-[(2-methoxyphenyl)methyl]-2-(oxolan-2-ylmethylamino)ethanamide
  • MLS000057813
  • SMR000063135
  • T5225306

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens chromobox homolog 1 Starlite/ChEMBL No references
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Loa Loa (eye worm) heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Giardia lamblia Fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Onchocerca volvulus Get druggable targets OG5_129545 All targets in OG5_129545
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Theileria parva hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum Chromobox protein homolog 5, putative Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Treponema pallidum fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Onchocerca volvulus Heterochromatin protein 1 homolog Get druggable targets OG5_129545 All targets in OG5_129545
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Brugia malayi Heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.8 %
Mycobacterium ulcerans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 26.9 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0427 0.0591
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0685 0.0916
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0562 0.111
Brugia malayi serine/threonine-protein kinase 6 0.006 0.0781 0.1121
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0171 0.2733 0.3062
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0024 0.0157 0.1166
Trypanosoma brucei cdc2-related kinase 1 0.0046 0.0547 0.2443
Brugia malayi serine/threonine protein kinase 6 0.006 0.0781 0.1121
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0052 0.0033
Echinococcus multilocularis tyrosine kinase 0.0019 0.0073 0.0051
Schistosoma mansoni tyrosine kinase 0.0188 0.3028 0.3012
Leishmania major hypothetical protein, conserved 0.0043 0.0497 0.2983
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0547 0.0526
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0052 0.0051
Trichomonas vaginalis set domain proteins, putative 0.0286 0.4749 0.6812
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0078 0.1094 0.6978
Echinococcus multilocularis protein kinase c epsilon type 0.0022 0.0113 0.009
Loa Loa (eye worm) hypothetical protein 0.0046 0.054 0.0585
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0034 0.0329 0.1368
Echinococcus multilocularis c src tyrosine kinase 0.0023 0.0138 0.0115
Loa Loa (eye worm) hypothetical protein 0.0043 0.0497 0.0536
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.003 0.0266 0.0244
Echinococcus granulosus tyrosine protein kinase Src42A 0.0052 0.0651 0.063
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0024 0.0157 0.0134
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0412 0.6964 1
Echinococcus multilocularis cyclins 0.0053 0.0672 0.0651
Echinococcus multilocularis tyrosine protein kinase Srms 0.0049 0.0586 0.0565
Schistosoma mansoni fkbp-rapamycin associated protein 0.0024 0.015 0.0128
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0052 0.0645 0.0624
Echinococcus granulosus nervana 2 0.0021 0.0096 0.0073
Schistosoma mansoni tyrosine kinase 0.0149 0.2344 0.2326
Brugia malayi Immunoglobulin I-set domain containing protein 0.0046 0.054 0.0776
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0024 0.0157 0.1166
Echinococcus multilocularis plexin a4 0.0021 0.0095 0.0072
Schistosoma mansoni tyrosine kinase 0.0052 0.0651 0.063
Echinococcus granulosus cyclins 0.0053 0.0672 0.0651
Trypanosoma cruzi cyclin, putative 0.0103 0.1546 0.2162
Echinococcus multilocularis cyclin dependent kinase 1 0.0046 0.0547 0.0526
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.2733 0.2716
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0082 0.1178 0.1919
Echinococcus granulosus tyrosine protein kinase ABL1 0.0019 0.0073 0.0051
Schistosoma mansoni chromobox protein 0.0084 0.121 0.119
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0412 0.6964 1
Loa Loa (eye worm) AUR protein kinase 0.006 0.0781 0.0856
Giardia lamblia Kinase, AGC PKA 0.0024 0.0157 0.0179
Echinococcus granulosus plexin a4 0.0021 0.0095 0.0072
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0046 0.0547 0.5494
Loa Loa (eye worm) hypothetical protein 0.0035 0.0352 0.0372
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0412 0.6964 1
Echinococcus multilocularis Zinc finger, PHD finger 0.007 0.0954 0.0933
Entamoeba histolytica hypothetical protein 0.0024 0.015 0.0143
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.0651 0.063
Echinococcus granulosus tyrosine protein kinase Fyn 0.0052 0.0651 0.063
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0625 0.0876
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0023 0.0138 0.0115
Loa Loa (eye worm) CDC7 protein kinase 0.006 0.079 0.0867
Echinococcus multilocularis 0.0018 0.0052 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0791 0.1116
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.007 0.0954 0.1305
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.007 0.0954 0.0933
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0052 0.0645 0.0624
Entamoeba histolytica protein kinase domain containing protein 0.006 0.0781 0.1055
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0018 0.0055 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0473 0.0658
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0073 0.0057
Trichomonas vaginalis cyclin A, putative 0.0103 0.1546 0.2202
Trichomonas vaginalis cyclin B3, putative 0.0053 0.0672 0.0944
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0685 0.0962
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0078 0.1094 0.1211
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0352 0.0372
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0444 0.0422
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0232 0.3807 0.3793
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0037 0.0384 0.0409
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0685 0.0916
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.0266 0.0382
Plasmodium falciparum serine/threonine protein kinase, putative 0.006 0.0781 0.8082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.063 0.0883
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0497 0.0693
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.007 0.0954 0.0933
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0685 0.7018
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.007 0.0954 0.0933
Schistosoma mansoni hypothetical protein 0.0035 0.0352 0.033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.5922 0.85
Echinococcus multilocularis cyclins 0.0053 0.0672 0.0651
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0482 0.046
Trypanosoma cruzi aurora B kinase, putative 0.006 0.0781 0.1055
Loa Loa (eye worm) hypothetical protein 0.0103 0.1546 0.1721
Brugia malayi hypothetical protein 0.0046 0.054 0.0776
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.007 0.0954 1
Trichomonas vaginalis cyclin B, putative 0.0103 0.1546 0.2202
Trichomonas vaginalis cyclin D, putative 0.0053 0.0672 0.0944
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0562 0.0785
Echinococcus granulosus cyclin b3 0.0053 0.0672 0.0651
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0377 0.0519
Onchocerca volvulus 0.006 0.079 0.1594
Trichomonas vaginalis esterase, putative 0.0043 0.0497 0.0693
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.015 0.0193
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0018 0.0052 0.0029
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0019 0.0073 0.0031
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.0384 0.0362
Brugia malayi Cyclin, N-terminal domain containing protein 0.0103 0.1546 0.222
Giardia lamblia Kinase, STE STE20 0.0078 0.1094 0.1776
Entamoeba histolytica PH domain containing protein kinase, putative 0.0026 0.0193 0.0204
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.5922 0.85
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0073 0.0057
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0021 0.0096 0.0073
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.006 0.0791 0.3647
Onchocerca volvulus 0.0286 0.4749 1
Toxoplasma gondii hypothetical protein 0.0041 0.0446 0.4373
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.063 0.0883
Toxoplasma gondii AGC kinase 0.0035 0.0341 0.3206
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0791 0.1116
Echinococcus multilocularis Glutaredoxin protein 5 0.0021 0.0096 0.0073
Brugia malayi Protein kinase domain containing protein 0.0019 0.0073 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0531 0.0741
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.007 0.0954 0.1052
Schistosoma mansoni tyrosine kinase 0.0019 0.0073 0.0051
Brugia malayi serine/threonine kinase 12 0.006 0.0781 0.1121
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.015 0.0128
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0586 1 1
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0377 0.0519
Schistosoma mansoni tyrosine kinase 0.0024 0.0162 0.0139
Echinococcus multilocularis cyclins 0.0053 0.0672 0.0651
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0052 0.0651 0.063
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0586 1 1
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0625 0.0876
Loa Loa (eye worm) hypothetical protein 0.0017 0.0039 0.0019
Echinococcus granulosus chromobox protein 1 0.0084 0.121 0.119
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0685 0.0962
Echinococcus multilocularis tyrosine protein kinase shark 0.0019 0.0073 0.0051
Loa Loa (eye worm) hypothetical protein 0.0046 0.054 0.0585
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0444 0.0422
Echinococcus granulosus twitchin 0.0057 0.0737 0.0716
Schistosoma mansoni protein kinase 0.0078 0.1094 0.1074
Loa Loa (eye worm) phosphatidylinositol 3 0.006 0.0791 0.0868
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.006 0.0791 0.1136
Brugia malayi hypothetical protein 0.0019 0.0073 0.0105
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0266 0.031
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0685 0.4236
Loa Loa (eye worm) TK protein kinase 0.0117 0.1789 0.1996
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.007 0.0954 0.1305
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0497 0.0693
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.025 0.4111 0.6915
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.5922 0.8492
Entamoeba histolytica protein kinase, putative 0.0037 0.0377 0.0471
Onchocerca volvulus 0.0043 0.0497 0.0973
Leishmania major cyclin 0.0103 0.1546 1
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.015 0.0128
Schistosoma mansoni nephrin 0.0054 0.0676 0.0655
Schistosoma mansoni vav2 0.0018 0.0059 0.0036
Schistosoma mansoni vesicular amine transporter 0.0048 0.0583 0.0561
Loa Loa (eye worm) AUR protein kinase 0.006 0.0781 0.0856
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0073 0.0057
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.0547 0.0764
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0018 0.0055 0.0032
Echinococcus granulosus cyclin B 0.0103 0.1546 0.1527
Echinococcus multilocularis chromobox protein 1 0.0084 0.121 0.119
Echinococcus granulosus tyrosine protein kinase Blk 0.0049 0.0586 0.0565
Loa Loa (eye worm) hypothetical protein 0.006 0.0783 0.0859
Giardia lamblia PHD finger protein 15 0.0035 0.0352 0.0512
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0685 0.0916
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0342 0.0468
Echinococcus multilocularis cyclins 0.0053 0.0672 0.0651
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.005 0.0609 0.0587
Loa Loa (eye worm) hypothetical protein 0.0037 0.0383 0.0407
Loa Loa (eye worm) cyclin domain-containing protein 0.0165 0.263 0.2946
Plasmodium falciparum cyclin 0.0053 0.0672 0.688
Mycobacterium tuberculosis Conserved protein 0.0043 0.0497 0.0979
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0046 0.054 0.0519
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0103 0.1546 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.003 0.0266 0.0244
Brugia malayi Protein kinase domain containing protein 0.0171 0.2733 0.3924
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0109 0.1654 0.1634
Brugia malayi Variant SH3 domain containing protein 0.0016 0.0023 0.0033
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0073 0.0057
Echinococcus multilocularis tyrosine protein kinase Abl 0.0023 0.0138 0.0115
Echinococcus granulosus epidermal growth factor receptor 0.0218 0.3558 0.3543
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.1756 0.1738
Onchocerca volvulus Tyrosine kinase homolog 0.0157 0.2483 0.5189
Echinococcus multilocularis neuroglian 0.0054 0.0676 0.0655
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.006 0.0781 0.1055
Echinococcus multilocularis raf serine:threonine protein kinase 0.0227 0.3713 0.3698
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0052 0.0074
Trypanosoma cruzi cyclin, putative 0.0103 0.1546 0.2162
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0033
Echinococcus granulosus nervana 2 0.0021 0.0096 0.0073
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0052 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0266 0.0359
Trypanosoma brucei protein kinase, putative 0.0054 0.0685 0.3121
Echinococcus multilocularis cyclin b3 0.0053 0.0672 0.0651
Entamoeba histolytica cell division protein kinase 2, putative 0.0046 0.0547 0.0717
Trichomonas vaginalis cyclin B, putative 0.0053 0.0672 0.0944
Loa Loa (eye worm) raf kinase 0.0216 0.3529 0.3961
Loa Loa (eye worm) plexin A 0.0021 0.0095 0.0081
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0497 0.0476
Brugia malayi SH2 domain containing protein 0.0019 0.0073 0.0105
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0685 0.0916
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0685 0.1078
Entamoeba histolytica protein kinase, putative 0.0052 0.0645 0.0859
Loa Loa (eye worm) hypothetical protein 0.0046 0.054 0.0585
Brugia malayi SH2 domain containing protein 0.0019 0.0073 0.0105
Schistosoma mansoni plexin 0.0017 0.0039 0.0016
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.006 0.0791 0.495
Echinococcus granulosus tyrosine kinase 0.0049 0.0586 0.0565
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0497 0.2198
Echinococcus granulosus neuroglian 0.0054 0.0676 0.0655
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0024 0.015 0.0128
Loa Loa (eye worm) AGC/AKT protein kinase 0.0037 0.0377 0.04
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0377 0.0519
Schistosoma mansoni tyrosine kinase 0.0023 0.0138 0.0115
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0497 0.0476
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0232 0.3807 0.3793
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0018 0.0052 0.0029
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0352 0.033
Onchocerca volvulus 0.005 0.0609 0.1209
Giardia lamblia Kinase, CMGC CDK 0.0046 0.0547 0.0844
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.015 0.0193
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.101 0.1115
Brugia malayi protein kinase C II. 0.0022 0.0113 0.0163
Brugia malayi Cytochrome P450 family protein 0.0045 0.0531 0.0763
Echinococcus granulosus tyrosine protein kinase Fyn 0.0052 0.0651 0.063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.063 0.0883
Loa Loa (eye worm) phosphatidylinositol 3 0.003 0.0266 0.0275
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0394 0.6648 0.9542
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0134 0.208 0.2987
Onchocerca volvulus 0.0043 0.0497 0.0973
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0685 0.0663
Trypanosoma cruzi cyclin 6, putative 0.0103 0.1546 0.2162
Echinococcus granulosus tyrosine protein kinase Lyn 0.0056 0.0712 0.0691
Brugia malayi Tyrosine-protein kinase abl-1 0.0023 0.0138 0.0198
Brugia malayi Furin-like cysteine rich region family protein 0.0218 0.3558 0.5109
Schistosoma mansoni serine/threonine-protein kinase 0.0026 0.0193 0.0171
Giardia lamblia G2/mitotic-specific cyclin B 0.0103 0.1546 0.2546
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.5922 0.85
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0645 0.0905
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.063 0.0883
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0791 0.1116
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0052 0.0074
Plasmodium vivax protein kinase Crk2 0.0046 0.0547 0.5494
Brugia malayi Heterochromatin protein 1 0.0084 0.121 0.1738
Echinococcus granulosus Immunoglobulin 0.0046 0.054 0.0519
Brugia malayi Bromodomain containing protein 0.0035 0.0352 0.0506
Entamoeba histolytica PH domain containing protein kinase, putative 0.0026 0.0193 0.0204
Echinococcus granulosus peregrin 0.0035 0.0352 0.033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0589 0.0824
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0046 0.0547 0.0526
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0051 0.063 0.2853
Brugia malayi protein-tyrosine kinase 0.0049 0.0586 0.0842
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0266 0.031
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0073 0.0057
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0168 0.2681 0.3803
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0078 0.1094 0.1508
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.007 0.0954 0.1349
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0645 0.0905
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.007 0.0954 0.4447
Brugia malayi p70 ribosomal S6 kinase beta 0.0035 0.0341 0.049
Loa Loa (eye worm) hypothetical protein 0.0046 0.054 0.0585
Loa Loa (eye worm) hypothetical protein 0.0047 0.0562 0.0609
Loa Loa (eye worm) TK protein kinase 0.004 0.0432 0.0462
Giardia lamblia Aurora kinase 0.006 0.0781 0.1242
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0367 0.0345
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0497 0.1647
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0685 0.0748
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.006 0.0791 0.495
Loa Loa (eye worm) TK/ROR protein kinase 0.0018 0.0055 0.0036
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0497 0.0693
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0497 0.0693
Brugia malayi Protein kinase domain containing protein 0.0052 0.0645 0.0926
Loa Loa (eye worm) phosphatidylinositol kinase 0.0018 0.0052 0.0033
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.121 0.1341
Mycobacterium tuberculosis Conserved protein 0.0043 0.0497 0.0979
Trichomonas vaginalis chromobox protein, putative 0.0084 0.121 0.1718
Toxoplasma gondii aurora kinase 0.006 0.0781 0.8082
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0052 0.0647 0.0626
Brugia malayi Immunoglobulin I-set domain containing protein 0.0117 0.1789 0.257
Giardia lamblia Hypothetical protein 0.0053 0.0672 0.1057
Schistosoma mansoni tyrosine kinase 0.0218 0.3558 0.3543
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0037 0.0384 0.0552
Echinococcus multilocularis tyrosine protein kinase HCK 0.004 0.0432 0.041
Echinococcus multilocularis peregrin 0.0035 0.0352 0.033
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.006 0.0791 0.107
Mycobacterium tuberculosis Conserved protein 0.0043 0.0497 0.0979
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0078 0.1094 0.1571
Trypanosoma brucei mitotic cyclin 6 0.0103 0.1546 0.7367
Onchocerca volvulus 0.0019 0.0073 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0473 0.0658
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0052 0.0033
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0073 0.0057
Brugia malayi Cyclin, N-terminal domain containing protein 0.0103 0.1546 0.222
Echinococcus granulosus cyclins 0.0053 0.0672 0.0651
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0427 0.0591
Brugia malayi jmjC domain containing protein 0.0043 0.0482 0.0693
Echinococcus granulosus serine threonine protein kinase nrc 0.0024 0.0157 0.0134
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0018 0.0052 0.0051
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0024 0.015 0.0128
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0589 0.0824
Schistosoma mansoni phosphatidylinositol 4-kinase 0.007 0.0954 0.0933
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0113 0.009
Loa Loa (eye worm) TK protein kinase 0.0049 0.0586 0.0637
Toxoplasma gondii ABC1 family protein 0.0043 0.0497 0.4942
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0019 0.0073 0.0051
Trichomonas vaginalis CMGC family protein kinase 0.006 0.079 0.1114
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0023 0.0138 0.0115
Giardia lamblia GTOR 0.006 0.0791 0.126
Echinococcus granulosus cyclins 0.0053 0.0672 0.0651
Trichomonas vaginalis STE family protein kinase 0.0078 0.1094 0.1552
Echinococcus granulosus c src tyrosine kinase 0.0023 0.0138 0.0115
Entamoeba histolytica protein kinase, putative 0.0035 0.0341 0.0418
Loa Loa (eye worm) hypothetical protein 0.0043 0.0497 0.0536
Loa Loa (eye worm) phosphatidylinositol 3 0.0521 0.8874 1
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0547 0.0526
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0314 0.5237 0.7514
Loa Loa (eye worm) phosphatidylinositol 3 0.0116 0.1764 0.1967
Echinococcus multilocularis epidermal growth factor receptor 0.0218 0.3558 0.3543
Echinococcus granulosus cyclin B3 1 0.0053 0.0672 0.0651
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.003 0.0266 0.0244
Trichomonas vaginalis cyclin B, putative 0.0103 0.1546 0.2202
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0046 0.0547 0.0593
Onchocerca volvulus 0.0019 0.0073 0.0072
Loa Loa (eye worm) hypothetical protein 0.0024 0.015 0.0144
Echinococcus granulosus tyrosine kinase 0.0019 0.0073 0.0051
Schistosoma mansoni tyrosine kinase 0.0052 0.0651 0.063
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0352 0.033
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.5922 1
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0321 0.0438
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.015 0.0486
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.007 0.0954 0.137
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.015 0.0216
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0113 0.009
Entamoeba histolytica protein kinase, putative 0.006 0.0781 0.1055
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.006 0.0781 0.076
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0645 0.0905
Echinococcus granulosus serine/threonine protein kinase 0.0026 0.0193 0.0171
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0685 0.0962
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0497 0.0979
Plasmodium falciparum phd finger protein, putative 0.0035 0.0352 0.3334
Trichomonas vaginalis AGC family protein kinase 0.006 0.0781 0.11
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.007 0.0954 1
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0018 0.0052 0.0029
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0018 0.0052 0.0029
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0352 0.033
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0018 0.0052 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0589 0.0824
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0073 0.0057
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0024 0.0157 0.0152
Echinococcus granulosus tyrosine protein kinase Fyn 0.0052 0.0651 0.063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0589 0.0824
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0025 0.0167 0.1282
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0497 0.4942
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0428 0.0592
Brugia malayi Protein kinase domain containing protein 0.0019 0.0073 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0167 0.0217
Echinococcus granulosus tyrosine protein kinase Src64B 0.0052 0.0651 0.063
Loa Loa (eye worm) AUR protein kinase 0.006 0.0781 0.0856
Giardia lamblia Cyclin A 0.0053 0.0672 0.1057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0589 0.0824
Schistosoma mansoni serine/threonine-protein kinase 0.0026 0.0193 0.0171
Trypanosoma cruzi Protein kinase B 0.0026 0.0193 0.0204
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0046 0.0547 0.3317
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0022 0.0113 0.009
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0497 0.0979
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.003 0.0266 0.1056
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0049 0.0586 0.0565
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.1756 0.1738
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0531 0.0575
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0497 0.0476
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0427 0.0591
Brugia malayi SRC-1 0.0052 0.0651 0.0935
Brugia malayi beta-lactamase family protein 0.0043 0.0497 0.0714
Trypanosoma cruzi target of rapamycin kinase 3 0.0051 0.063 0.0837
Brugia malayi Protein kinase domain containing protein 0.0082 0.1175 0.1687
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.0651 0.063
Onchocerca volvulus 0.0019 0.0073 0.0072
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.006 0.0791 0.3647
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.5922 0.85
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0046 0.054 0.0519
Trichomonas vaginalis AGC family protein kinase 0.006 0.0781 0.11
Onchocerca volvulus 0.006 0.079 0.1594
Schistosoma mansoni tyrosine kinase 0.0138 0.216 0.2142
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0149 0.2344 0.2326
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0017 0.0039 0.0018
Loa Loa (eye worm) hypothetical protein 0.0032 0.0299 0.0312
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0352 0.3334
Brugia malayi plexin A 0.0021 0.0095 0.0136
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.007 0.0954 0.1305
Onchocerca volvulus 0.0019 0.0073 0.0072
Brugia malayi Protein kinase domain containing protein 0.006 0.079 0.1135
Leishmania major phosphatidylinositol 3-related kinase, putative 0.003 0.0266 0.1433
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0266 0.0359
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0051 0.063 0.3872
Brugia malayi jmjC domain containing protein 0.0115 0.1756 0.2522
Echinococcus multilocularis insulin receptor 0.0188 0.3028 0.3012
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0052 0.0651 0.063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0213 0.0283
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0482 0.046
Loa Loa (eye worm) beta-lactamase 0.0043 0.0497 0.0536
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0497 0.0536
Loa Loa (eye worm) hypothetical protein 0.0103 0.1546 0.1721
Trichomonas vaginalis AGC family protein kinase 0.006 0.0781 0.11
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0685 0.3121
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.015 0.0216
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.5922 0.85
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0377 0.0519
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0173 0.2771 0.3979
Trichomonas vaginalis STE family protein kinase 0.0078 0.1094 0.1552
Leishmania major phosphatidylinositol 3-kinase, putative 0.007 0.0954 0.6036
Echinococcus granulosus Protein kinase C brain isozyme 0.0022 0.0113 0.009
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0377 0.0519
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0036 0.0375 0.1592
Toxoplasma gondii FATC domain-containing protein 0.0024 0.015 0.1092
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0052 0.0651 0.063
Schistosoma mansoni tyrosine kinase 0.0109 0.1654 0.1634
Echinococcus multilocularis chromobox protein 1 0.0084 0.121 0.119
Entamoeba histolytica cyclin family protein 0.0053 0.0672 0.0898
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0266 0.0359
Loa Loa (eye worm) hypothetical protein 0.018 0.2893 0.3242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0428 0.0592
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0035 0.0341 0.0359
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0412 0.6964 1
Trichomonas vaginalis AGC family protein kinase 0.006 0.0781 0.11
Onchocerca volvulus Alhambra homolog 0.0035 0.0352 0.0665
Brugia malayi chromobox protein homolog 3 0.0047 0.0562 0.0807
Onchocerca volvulus 0.0037 0.0383 0.0731
Loa Loa (eye worm) hypothetical protein 0.0072 0.0992 0.1094
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0377 0.0519
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.5922 0.85
Echinococcus multilocularis cyclin B 0.0103 0.1546 0.1527
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.2757 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.054 0.0585
Trichomonas vaginalis CMGC family protein kinase 0.006 0.079 0.1114
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0232 0.3807 0.5467
Echinococcus multilocularis cyclins 0.0053 0.0672 0.0651
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0377 0.0519
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0412 0.6964 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0497 0.0536
Echinococcus granulosus cyclin dependent kinase 0.0046 0.0547 0.0526
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0134 0.208 0.2934
Loa Loa (eye worm) hypothetical protein 0.0043 0.0497 0.0536
Brugia malayi Immunoglobulin I-set domain containing protein 0.0201 0.3259 0.468
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.007 0.0954 0.1349
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0685 0.0663
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0116 0.1764 0.2477
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.2757 1
Entamoeba histolytica protein kinase, putative 0.006 0.0781 0.1055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0428 0.0592
Echinococcus granulosus fibroblast growth factor receptor 4 0.0109 0.1654 0.1634
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0367 0.0345
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0201 0.3259 0.3657
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.5922 0.8492
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0134 0.208 1
Echinococcus multilocularis nervana 2 0.0021 0.0096 0.0073
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0134 0.208 0.2934
Schistosoma mansoni protein kinase 0.006 0.0781 0.076
Plasmodium vivax serine/threonine protein kinase 6, putative 0.006 0.0781 0.8082
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0165 0.263 0.2613
Schistosoma mansoni atypical protein kinase C 0.0022 0.0113 0.009
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0052 0.0651 0.063
Schistosoma mansoni cyclins 0.0053 0.0672 0.0651
Brugia malayi Protein kinase domain containing protein 0.0019 0.0073 0.0105
Echinococcus multilocularis roundabout 2 0.006 0.0783 0.0762
Schistosoma mansoni tyrosine kinase 0.0019 0.0073 0.0051
Echinococcus granulosus defective proboscis extension response 0.0046 0.054 0.0519
Onchocerca volvulus 0.0018 0.0052 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0497 0.0645
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0018 0.0052 0.0051
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.0384 0.0362
Schistosoma mansoni chromobox protein 0.0084 0.121 0.119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.015 0.0193
Schistosoma mansoni tyrosine kinase 0.0149 0.2344 0.2326
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0497 0.0979
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0046 0.054 0.0519
Echinococcus granulosus dual specificity mitogen activated protein 0.0078 0.1094 0.1074
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.006 0.0791 0.107
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0024 0.015 0.0143
Schistosoma mansoni tyrosine kinase 0.0138 0.216 0.2142
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0352 0.3334
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0367 0.0345
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0188 0.3028 0.3012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0514 0.0716
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0046 0.0547 0.0593
Schistosoma mansoni cell adhesion molecule 0.0052 0.0647 0.0626
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.006 0.0791 0.077
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0497 0.0979
Echinococcus multilocularis 0.0064 0.0849 0.0828
Loa Loa (eye worm) TK/ABL protein kinase 0.0019 0.0073 0.0057
Echinococcus granulosus epidermal growth factor receptor 0.0149 0.2344 0.2326
Loa Loa (eye worm) hypothetical protein 0.0025 0.0167 0.0163
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0134 0.208 0.297
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0024 0.0157 0.0134
Echinococcus granulosus protein kinase c epsilon type 0.0022 0.0113 0.009
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0024 0.015 0.0143
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.0547 0.0764
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0497 0.0693
Brugia malayi Protein kinase domain containing protein 0.0037 0.0377 0.0541
Trichomonas vaginalis STE family protein kinase 0.0078 0.1094 0.1552
Schistosoma mansoni jumonji domain containing protein 0.0092 0.1341 0.1321
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0046 0.0547 0.3317
Leishmania major phosphatidylinositol 3-kinase, putative 0.003 0.0266 0.1433
Entamoeba histolytica cyclin family protein 0.0053 0.0672 0.0898
Echinococcus multilocularis cyclins 0.0053 0.0672 0.0651
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.007 0.0954 0.1349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0469 0.0651
Echinococcus multilocularis cyclin dependent kinase 0.0046 0.0547 0.0526
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0497 0.0645
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.015 0.0143
Echinococcus multilocularis tyrosine protein kinase Blk 0.0049 0.0586 0.0565
Entamoeba histolytica protein kinase, putative 0.004 0.0432 0.055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.063 0.0883
Schistosoma mansoni hypothetical protein 0.0018 0.0052 0.0029
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.007 0.0954 0.0933
Schistosoma mansoni tyrosine kinase 0.0188 0.3028 0.3012
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0019 0.0073 0.0051
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0026 0.0193 0.0204
Entamoeba histolytica protein kinase, putative 0.0037 0.0377 0.0471
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0165 0.263 0.2613
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0497 0.0979
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0046 0.0547 0.0593
Echinococcus granulosus CDC7 cell division cycle 7 0.006 0.079 0.0769
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0018 0.0052 0.0029
Trypanosoma cruzi CYC2-like cyclin, putative 0.0103 0.1546 0.2162
Brugia malayi Raf kinase 0.0219 0.358 0.514
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.006 0.0781 0.1055
Trypanosoma brucei rac serine-threonine kinase, putative 0.0037 0.0377 0.1604
Entamoeba histolytica cyclin, putative 0.0053 0.0672 0.0898
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0367 0.3498
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0482 0.046
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0052 0.0651 0.063
Trichomonas vaginalis cyclins, putative 0.0063 0.0835 0.1179
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.4604 1
Echinococcus granulosus tyrosine protein kinase shark 0.0019 0.0073 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0367 0.0345
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0676 0.0949
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.0594 0.0573
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.006 0.0791 0.077
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0109 0.1654 0.1634
Echinococcus multilocularis aurora kinase A 0.006 0.0781 0.076
Onchocerca volvulus 0.0139 0.2164 0.4511
Trichomonas vaginalis cyclins, putative 0.0053 0.0672 0.0944
Schistosoma mansoni cyclin B 0.0103 0.1546 0.1527
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0266 0.0359
Echinococcus multilocularis Immunoglobulin 0.0046 0.054 0.0519
Loa Loa (eye worm) hypothetical protein 0.006 0.0783 0.0859
Echinococcus granulosus jumonji domain containing protein 0.0049 0.0594 0.0573
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0672 0.0944
Trichomonas vaginalis CMGC family protein kinase 0.006 0.079 0.1114
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0019 0.0073 0.0051
Echinococcus multilocularis epidermal growth factor receptor 0.0149 0.2344 0.2326
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0018 0.0052 0.0029
Brugia malayi Plexin repeat family protein 0.0017 0.0039 0.0057
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0344 0.0322
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.3713 0.3698
Loa Loa (eye worm) TK/INSR protein kinase 0.0188 0.3028 0.3396
Entamoeba histolytica protein kinase 2, putative 0.0024 0.0157 0.0152
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0133 0.2062 0.2304
Echinococcus granulosus roundabout 2 0.006 0.0783 0.0762
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.006 0.0791 0.107
Loa Loa (eye worm) hypothetical protein 0.0019 0.0073 0.0057
Trypanosoma cruzi cdc2-related kinase 1 0.0046 0.0547 0.0717
Brugia malayi Protein kinase domain containing protein 0.0046 0.0547 0.0786
Brugia malayi Cyclin, N-terminal domain containing protein 0.0165 0.263 0.3776
Trichomonas vaginalis cyclin B, putative 0.0103 0.1546 0.2202
Echinococcus multilocularis cyclin dependent kinase 5 0.0046 0.0547 0.0526
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0645 0.0624
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.0651 0.063
Echinococcus granulosus chromobox protein 1 0.0084 0.121 0.119
Onchocerca volvulus 0.0019 0.0073 0.0072
Loa Loa (eye worm) TK/EGFR protein kinase 0.0218 0.3558 0.3994
Brugia malayi PHD-finger family protein 0.0035 0.0352 0.0506
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0052 0.0651 0.063
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0497 0.0979
Trichomonas vaginalis cyclin D, putative 0.0053 0.0672 0.0944
Schistosoma mansoni serine/threonine protein kinase 0.006 0.079 0.0769
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0367 0.0345
Echinococcus granulosus aurora kinase A 0.006 0.0781 0.076
Schistosoma mansoni tyrosine kinase 0.0023 0.0138 0.0115
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0038 0.0403 0.0381
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0367 0.0345
Loa Loa (eye worm) SRC-1 0.0052 0.0651 0.071
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0685 0.0663
Brugia malayi Pre-SET motif family protein 0.0036 0.0367 0.0527
Plasmodium falciparum protein kinase 5 0.0046 0.0547 0.5494
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0412 0.6964 1
Echinococcus multilocularis nervana 2 0.0021 0.0096 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0589 0.0824
Plasmodium vivax SET domain protein, putative 0.0036 0.0367 0.3498
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0113 0.009
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0052 0.0651 0.063
Brugia malayi Fibronectin type III domain containing protein 0.0046 0.054 0.0776
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0109 0.1654 0.1634
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0562 0.0785
Trypanosoma brucei cdc2-related kinase 3 0.0046 0.0547 0.2443
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0018 0.0052 0.0029
Entamoeba histolytica hypothetical protein 0.0348 0.5838 0.8371
Echinococcus multilocularis rac serine:threonine kinase 0.0026 0.0193 0.0171
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0188 0.3028 0.3012
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0049 0.0586 0.0565
Loa Loa (eye worm) hypothetical protein 0.0046 0.054 0.0585
Echinococcus granulosus cyclins 0.0053 0.0672 0.0651
Echinococcus multilocularis cyclin dependent kinase 1 0.0046 0.0547 0.0526
Toxoplasma gondii target of rapamycin (TOR), putative 0.0049 0.0589 0.5954
Brugia malayi MAP kinase sur-1 0.0054 0.0685 0.0983
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0078 0.1094 0.5141
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0073 0.0057
Loa Loa (eye worm) hypothetical protein 0.0043 0.0497 0.0536
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0018 0.0052 0.0029
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0073 0.0057
Trypanosoma cruzi cdc2-related kinase 3 0.0046 0.0547 0.0717
Echinococcus granulosus serine protein kinase ATM 0.0024 0.015 0.0128
Echinococcus multilocularis dual specificity mitogen activated protein 0.0078 0.1094 0.1074
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0134 0.208 0.297
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0352 0.3334
Entamoeba histolytica protein kinase , putative 0.006 0.0781 0.1055
Echinococcus granulosus cyclin dependent kinase 5 0.0046 0.0547 0.0526
Echinococcus multilocularis cyclin B3 1 0.0053 0.0672 0.0651
Trichomonas vaginalis cyclins, putative 0.0103 0.1546 0.2202
Echinococcus granulosus Glutaredoxin protein 5 0.0021 0.0096 0.0073
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0781 0.076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0473 0.0658
Loa Loa (eye worm) hypothetical protein 0.0043 0.0487 0.0524
Echinococcus granulosus tyrosine protein kinase HCK 0.004 0.0432 0.041
Giardia lamblia Kinase, CMGC CDK 0.0046 0.0547 0.0844
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0321 0.0438
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.0547 0.0764
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.007 0.0954 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0609 0.0662
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.5922 0.5
Schistosoma mansoni tyrosine kinase 0.0138 0.216 0.2142
Trichomonas vaginalis cyclin B, putative 0.0103 0.1546 0.2202
Onchocerca volvulus 0.0043 0.0497 0.0973
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.2757 0.5943
Echinococcus granulosus serine:threonine protein kinase 12 B 0.006 0.0781 0.076
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0134 0.208 0.2062
Brugia malayi Protein kinase domain containing protein 0.0019 0.0073 0.0105
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0052 0.0645 0.0703
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0021 0.0096 0.0073
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0052 0.0645 0.0703
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0428 0.0592
Echinococcus granulosus protein kinase c iota type 0.0022 0.0113 0.009
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0482 0.0519
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0685 0.4236
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0134 0.208 0.297
Loa Loa (eye worm) hypothetical protein 0.0043 0.0497 0.0536
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.007 0.0954 0.1305
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.007 0.0954 0.6036
Loa Loa (eye worm) hypothetical protein 0.0036 0.0367 0.0389
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.003 0.0266 0.1056
Loa Loa (eye worm) hypothetical protein 0.0232 0.3807 0.4276
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0685 0.0663
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0497 0.0979
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0052 0.0651 0.063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.5922 0.85
Loa Loa (eye worm) hypothetical protein 0.006 0.0793 0.087
Onchocerca volvulus 0.0103 0.1546 0.3199
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0348 0.5838 0.8371
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0073 0.0057
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0497 0.0714
Echinococcus multilocularis CDC7 cell division cycle 7 0.006 0.079 0.0769
Trichomonas vaginalis chromobox protein, putative 0.0084 0.121 0.1718
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0685 0.0962
Trypanosoma cruzi cdc2-related kinase 3 0.0046 0.0547 0.0717
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0052 0.0033
Loa Loa (eye worm) hypothetical protein 0.0052 0.0647 0.0705
Brugia malayi Protein kinase domain containing protein 0.0019 0.0073 0.0105
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0342 0.0468
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0412 0.6964 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0266 0.0359
Echinococcus multilocularis cyclins 0.0053 0.0672 0.0651
Echinococcus granulosus raf serine:threonine protein kinase 0.0227 0.3713 0.3698
Onchocerca volvulus 0.0019 0.0073 0.0072
Leishmania major protein kinase, putative 0.006 0.0781 0.4879
Trichomonas vaginalis cyclins, putative 0.0103 0.1546 0.2202
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.5922 0.85
Brugia malayi phosphoinositide-dependent protein kinase I 0.0052 0.0645 0.0926
Brugia malayi beta-lactamase family protein 0.0043 0.0497 0.0714
Entamoeba histolytica protein kinase rad3, putative 0.0024 0.015 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0052 0.0051
Trichomonas vaginalis cyclins, putative 0.0103 0.1546 0.2202
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0022 0.0113 0.0102
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.006 0.0791 0.077
Brugia malayi Protein kinase domain containing protein 0.0188 0.3028 0.4348
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.006 0.0791 0.107
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0625 0.1243
Echinococcus multilocularis Immunoglobulin 0.0046 0.054 0.0519
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0685 0.0663
Echinococcus granulosus tyrosine protein kinase Src42A 0.0038 0.0403 0.0381
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0589 0.0824
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0497 0.0476
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0023 0.0138 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0469 0.0651
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0134 0.208 0.2934
Mycobacterium leprae Probable lipase LipE 0.0043 0.0497 0.1647
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.4141 0.4652
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0018 0.0052 0.0029
Schistosoma mansoni cyclin B3 0.0165 0.263 0.2613
Brugia malayi RhoGAP domain containing protein 0.0016 0.0023 0.0033
Echinococcus granulosus cyclins 0.0053 0.0672 0.0651
Echinococcus granulosus insulin receptor 0.0188 0.3028 0.3012
Echinococcus multilocularis protein kinase c iota type 0.0022 0.0113 0.009
Echinococcus granulosus cyclin dependent kinase 1 0.0046 0.0547 0.0526
Brugia malayi beta-lactamase 0.0043 0.0497 0.0714
Giardia lamblia Kinase, CDC7 0.006 0.079 0.1258
Echinococcus granulosus lysine specific demethylase 5A 0.0043 0.0482 0.046
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0052 0.0074
Trichomonas vaginalis cyclins, putative 0.0103 0.1546 0.2202
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0314 0.5237 0.7514
Brugia malayi Pre-SET motif family protein 0.0251 0.4141 0.5946
Brugia malayi cell division control protein 2 homolog 0.0046 0.0547 0.0786
Entamoeba histolytica cell division protein kinase 2, putative 0.0046 0.0547 0.0717
Trypanosoma brucei aurora B kinase 0.006 0.0781 0.3594
Echinococcus granulosus tyrosine protein kinase Srms 0.0019 0.0073 0.0051
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.006 0.0781 0.1055
Entamoeba histolytica cyclin, putative 0.0103 0.1546 0.2162
Plasmodium falciparum phosphatidylinositol 3-kinase 0.007 0.0954 1
Trypanosoma cruzi cdc2-related kinase 1 0.0046 0.0547 0.0717
Onchocerca volvulus 0.0018 0.0052 0.0026

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.631 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 1.9953 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 6.3096 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1473, AID2293, AID2577, AID2578, AID2587, AID2588, AID2589, AID2590, AID2592, AID2593, AID2595, AID2596, AID2597, AID2613, AID2671, AID488845] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) = 56.2341 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.