Detailed information for compound 1468597

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 389.464 | Formula: C21H28FN3O3
  • H donors: 2 H acceptors: 3 LogP: 2.51 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(CCCNC(=O)c1c(O)c2cc(F)cc3c2n(c1=O)C(C)CC3)CC
  • InChi: 1S/C21H28FN3O3/c1-4-24(5-2)10-6-9-23-20(27)17-19(26)16-12-15(22)11-14-8-7-13(3)25(18(14)16)21(17)28/h11-13,26H,4-10H2,1-3H3,(H,23,27)
  • InChiKey: JVKBVLNPPVEOHA-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus biogenic amine 5HT receptor 0.0054 0.0109 0.0176
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0653 0.1998 0.3235
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0035 0.0035
Echinococcus granulosus tumor protein p63 0.0326 0.0968 0.1568
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Brugia malayi steroid hormone receptor 0.003 0.0035 0.0056
Echinococcus multilocularis neuropeptide FF receptor 2 0.0054 0.0109 0.0109
Entamoeba histolytica hypothetical protein 0.0279 0.0817 0.2192
Plasmodium falciparum serine repeat antigen 4 0.0279 0.0817 0.2192
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.0056
Loa Loa (eye worm) CXXC zinc finger family protein 0.0056 0.0116 0.0187
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0035 0.0056
Leishmania major cathepsin L-like protease 0.1203 0.373 0.3966
Schistosoma mansoni adenoreceptor 0.0054 0.0109 0.0176
Schistosoma mansoni neuropeptide f receptor 76f 0.0054 0.0109 0.0176
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1203 0.373 0.373
Onchocerca volvulus 0.0054 0.0109 0.0291
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0054 0.0109 0.0176
Brugia malayi nuclear receptor NHR-88 0.003 0.0035 0.0056
Echinococcus granulosus g protein coupled receptor 0.0054 0.0109 0.0176
Brugia malayi CXXC zinc finger family protein 0.0056 0.0116 0.0187
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0058 0.0155
Schistosoma mansoni coup transcription factor 0.003 0.0035 0.0056
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0054 0.0109 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1203 0.373 1
Schistosoma mansoni biogenic amine receptor 0.0054 0.0109 0.0176
Echinococcus granulosus cathepsin L cysteine proteinase 0.1203 0.373 0.6039
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0093
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0046 0.0651
Brugia malayi Pre-SET motif family protein 0.0406 0.122 0.1975
Echinococcus granulosus lamin 0.0052 0.0105 0.017
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0059
Brugia malayi cathepsin L-like cysteine proteinase 0.0279 0.0817 0.1323
Entamoeba histolytica cysteine protease, putative 0.0653 0.1998 0.5357
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0124 0.0202
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0058 0.0814
Echinococcus multilocularis fmrfamide receptor 0.0054 0.0109 0.0109
Plasmodium vivax vivapain-1 0.0653 0.1998 0.5357
Echinococcus multilocularis dnaJ subfamily B 0.0796 0.2448 0.2448
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0059 0.0061
Brugia malayi hypothetical protein 0.0054 0.0109 0.0176
Onchocerca volvulus 0.0054 0.0109 0.0291
Brugia malayi fibroinase precursor 0.0279 0.0817 0.1323
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Entamoeba histolytica hypothetical protein 0.0035 0.0049 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0035 0.0056
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0058 0.0093
Echinococcus multilocularis G protein coupled receptor 139 0.0054 0.0109 0.0109
Echinococcus granulosus tar DNA binding protein 0.0128 0.0343 0.0555
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0001 0.0103
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0046 0.0085 0.1209
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0001 0.0218
Trypanosoma cruzi cysteine proteinase, putative 0.0653 0.1998 0.2125
Entamoeba histolytica hypothetical protein 0.0035 0.0049 0.0132
Schistosoma mansoni jumonji domain containing protein 0.0073 0.0171 0.0276
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0109 0.0176
Plasmodium vivax unspecified product 0.0375 0.112 0.3004
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0035 0.0056
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Trypanosoma cruzi major cysteine proteinase, putative 0.0279 0.0817 0.0869
Brugia malayi putative neuropeptide receptor 0.0054 0.0109 0.0176
Onchocerca volvulus 0.0054 0.0109 0.0291
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0279 0.0817 0.1323
Entamoeba histolytica acyl-coA synthetase, putative 0.0046 0.0085 0.0228
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0973 0.3005 0.3195
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1203 0.373 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1203 0.373 0.373
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0035 0.0056
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0046 0.0085 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1203 0.373 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0001 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0035 0.0056
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0034 0.0048 1
Schistosoma mansoni neuropeptide receptor 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0828 0.2549 0.4127
Brugia malayi cathepsin L precursor 0.0279 0.0817 0.1323
Onchocerca volvulus 0.0054 0.0109 0.0291
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0124 1
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0058 0.0814
Loa Loa (eye worm) hypothetical protein 0.0279 0.0817 0.1323
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1203 0.373 1
Echinococcus multilocularis expressed conserved protein 0.0089 0.0221 0.0221
Plasmodium falciparum serine repeat antigen 8 0.0279 0.0817 0.2192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1203 0.373 1
Giardia lamblia Encystation-specific protease 0.0279 0.0817 0.272
Echinococcus granulosus lamin dm0 0.0052 0.0105 0.017
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0029 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0109 0.0176
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0279 0.0817 0.272
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0279 0.0817 0.2192
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0035 0.0035
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1979 0.6177 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0001 0.0001
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0406 0.122 0.1975
Schistosoma mansoni cathepsin F (C01 family) 0.1203 0.373 0.6039
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0059 0.0059
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.0279 0.0817 0.2192
Echinococcus granulosus sex peptide receptor 0.0054 0.0109 0.0176
Echinococcus multilocularis cathepsin L cysteine protease 0.1203 0.373 0.373
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0019 0.0000003449 0.00000092469
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1203 0.373 0.6039
Brugia malayi follicle stimulating hormone receptor 0.0054 0.0109 0.0176
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0085 0.683
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0068 0.0183
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0001 0.0003
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0279 0.0817 0.2192
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0279 0.0817 0.1323
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0028 0.0046
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0046 0.0085 0.683
Brugia malayi Cathepsin L-like precursor 0.1203 0.373 0.6039
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0068 0.011
Echinococcus granulosus 7tm_1 domain containing protein 0.0054 0.0109 0.0176
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0109 0.0176
Brugia malayi neuropeptide F receptor 0.0054 0.0109 0.0176
Trypanosoma cruzi cysteine protease, putative 0.0653 0.1998 0.2125
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1203 0.373 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1203 0.373 1
Onchocerca volvulus 0.0037 0.0058 0.0155
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0279 0.0817 0.1323
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0028 0.0046
Trypanosoma cruzi cruzipain precursor, putative 0.3003 0.9402 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0028 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0058 0.0061
Onchocerca volvulus 0.0054 0.0109 0.0291
Trypanosoma cruzi cysteine peptidase, putative 0.0375 0.112 0.1192
Giardia lamblia Cathepsin L precursor 0.0279 0.0817 0.272
Entamoeba histolytica cysteine protease, putative 0.0653 0.1998 0.5357
Schistosoma mansoni hypothetical protein 0.0039 0.0064 0.0103
Plasmodium falciparum serine repeat antigen 3 0.0279 0.0817 0.2192
Echinococcus granulosus serotonin receptor 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0035 0.0035
Brugia malayi nuclear hormone receptor 0.003 0.0035 0.0056
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Schistosoma mansoni cathepsin F (C01 family) 0.1203 0.373 0.6039
Echinococcus multilocularis cysteine protease 0.1203 0.373 0.373
Loa Loa (eye worm) hypothetical protein 0.0145 0.0397 0.0643
Schistosoma mansoni biogenic amine (5HT) receptor 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0279 0.0817 0.1323
Brugia malayi G protein-coupled receptor 0.0054 0.0109 0.0176
Schistosoma mansoni hypothetical protein 0.0054 0.0109 0.0176
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0121 0.032 0.0518
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0001 0.0003
Onchocerca volvulus Cathepsin L homolog 0.1203 0.373 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.017
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0653 0.1998 0.2125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0109 0.0176
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.0109 0.0176
Schistosoma mansoni hypothetical protein 0.0039 0.0064 0.0103
Echinococcus multilocularis g protein coupled receptor 0.0054 0.0109 0.0109
Echinococcus granulosus neuropeptide receptor 0.0054 0.0109 0.0176
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0000003449 0.00000092469
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0058 0.0814
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1203 0.373 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0019 0.0031
Plasmodium vivax vivapain-3 0.0653 0.1998 0.5357
Echinococcus granulosus neuropeptide Y receptor 0.0054 0.0109 0.0176
Giardia lamblia Hypothetical protein 0.0279 0.0817 0.272
Echinococcus granulosus cathepsin b 0.1979 0.6177 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0054 0.0109 0.0176
Giardia lamblia Cathepsin L precursor 0.0279 0.0817 0.272
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0059 0.0158
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3003 0.9402 1
Echinococcus granulosus g protein coupled receptor 0.0054 0.0109 0.0176
Giardia lamblia Cathepsin L-like protease 0.0279 0.0817 0.272
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0124 0.0202
Brugia malayi RE15519p 0.0054 0.0109 0.0176
Brugia malayi Protein kinase domain containing protein 0.0031 0.0036 0.0058
Brugia malayi hypothetical protein 0.0054 0.0109 0.0176
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1203 0.373 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0036 0.0058
Brugia malayi cathepsin Z-like cysteine proteinase 0.0279 0.0817 0.1323
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0035 0.0056
Plasmodium falciparum serine repeat antigen 2 0.0279 0.0817 0.2192
Entamoeba histolytica cysteine protease, putative 0.1203 0.373 1
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.2041 0.2041
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0279 0.0817 0.1323
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0035 0.0056
Trypanosoma cruzi cysteine peptidase, putative 0.3003 0.9402 1
Loa Loa (eye worm) neuropeptide F receptor 0.0054 0.0109 0.0176
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0058 0.0061
Brugia malayi Cathepsin L-like precursor 0.1203 0.373 0.6039
Loa Loa (eye worm) hypothetical protein 0.0828 0.2549 0.4127
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0127 0.0205
Echinococcus multilocularis G-protein coupled receptor, putative 0.0054 0.0109 0.0109
Brugia malayi beta-lactamase family protein 0.0037 0.0058 0.0093
Entamoeba histolytica cysteine protease, putative 0.0653 0.1998 0.5357
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0035 0.0056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0035 0.0056
Echinococcus multilocularis serotonin receptor 0.0054 0.0109 0.0109
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0279 0.0817 0.1323
Toxoplasma gondii cathepsin CPL 0.1203 0.373 1
Plasmodium vivax vivapain-2 0.1203 0.373 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Brugia malayi Cathepsin L-like precursor 0.1203 0.373 0.6039
Entamoeba histolytica cysteine proteinase, putative 0.0653 0.1998 0.5357
Onchocerca volvulus 0.1203 0.373 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0279 0.0817 0.2192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1203 0.373 1
Brugia malayi hypothetical protein 0.0054 0.0109 0.0176
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3003 0.9402 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0054 0.0109 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1203 0.373 1
Trichomonas vaginalis replication factor C large subunit, putative 0.0019 0.0000003449 0.00000092469
Brugia malayi Papain family cysteine protease containing protein 0.0279 0.0817 0.1323
Onchocerca volvulus 0.1203 0.373 1
Loa Loa (eye worm) hypothetical protein 0.0279 0.0817 0.1323
Leishmania major cathepsin L-like protease 0.3003 0.9402 1
Leishmania major cathepsin L-like protease 0.1203 0.373 0.3966
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0109 0.0176
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0057 0.0092
Schistosoma mansoni histamine h1 receptor 0.0054 0.0109 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1203 0.373 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0059 0.0063
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0093
Echinococcus granulosus dro:myosuppressin receptor 0.0054 0.0109 0.0176
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0042 0.0593
Echinococcus multilocularis cathepsin L cysteine protease 0.1203 0.373 0.373
Echinococcus multilocularis neuropeptides capa receptor 0.0054 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0046 0.0084 0.0137
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0085 0.0228
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0046 0.0084 0.0137
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0035 0.0056
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0054 0.0109 0.0109
Echinococcus granulosus microtubule associated protein 2 0.0667 0.2041 0.3304
Plasmodium falciparum serine repeat antigen 7 0.0279 0.0817 0.2192
Brugia malayi jmjC domain containing protein 0.0037 0.0057 0.0092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0279 0.0817 0.2192
Loa Loa (eye worm) hypothetical protein 0.0048 0.0092 0.0149
Giardia lamblia Cysteine protease 0.0279 0.0817 0.272
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1203 0.373 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0054 0.0109 0.0176
Brugia malayi Calcitonin receptor-like protein seb-1 0.0145 0.0397 0.0643
Schistosoma mansoni hypothetical protein 0.0031 0.0036 0.0058
Echinococcus granulosus geminin 0.0176 0.0495 0.0802
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0239 0.0694 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0054 0.0109 0.0176
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0054 0.0109 0.0176
Onchocerca volvulus 0.1203 0.373 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.009 0.0146
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Plasmodium falciparum cysteine proteinase falcipain 3 0.1203 0.373 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0375 0.112 0.1814
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1203 0.373 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0054 0.0109 0.0176
Schistosoma mansoni cathepsin S (C01 family) 0.0279 0.0817 0.1323
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0054 0.0109 0.0176
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0058 0.0814
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0279 0.0817 0.2192
Entamoeba histolytica cysteine protease, putative 0.0653 0.1998 0.5357
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0054 0.0109 0.0109
Mycobacterium ulcerans beta-lactamase 0.0037 0.0058 0.4632
Plasmodium falciparum cysteine proteinase falcipain 1 0.0653 0.1998 0.5357
Schistosoma mansoni biogenic amine (5HT) receptor 0.0054 0.0109 0.0176
Brugia malayi beta-lactamase 0.0037 0.0058 0.0093
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0279 0.0817 0.2192
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0035 0.0056
Leishmania major cysteine peptidase A (CPA) 0.1203 0.373 0.3966
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0054 0.0109 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0035 0.0056
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1979 0.6177 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Schistosoma mansoni hypothetical protein 0.0047 0.0086 0.014
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0279 0.0817 0.1323
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0025 0.0019 0.0031
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0279 0.0817 0.2192
Onchocerca volvulus 0.0828 0.2549 0.6834
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0035 0.0056
Mycobacterium tuberculosis Conserved protein 0.0037 0.0058 0.0814
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3003 0.9402 1
Trypanosoma cruzi major cysteine proteinase, putative 0.2078 0.649 0.6902
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.066 0.1068
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0279 0.0817 0.2192
Brugia malayi Intermediate filament tail domain containing protein 0.0052 0.0105 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1203 0.373 1
Giardia lamblia Cathepsin B precursor 0.0973 0.3005 1
Trypanosoma cruzi cruzipain precursor, putative 0.0375 0.112 0.1192
Brugia malayi Uncoordinated protein 44 0.0031 0.0036 0.0058
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0046 0.0085 0.683
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0085 0.0138
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0031 0.0036 0.0036
Brugia malayi hypothetical protein 0.0228 0.066 0.1068
Brugia malayi Dopamine receptor protein 1 0.0054 0.0109 0.0176
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3003 0.9402 1
Brugia malayi hypothetical protein 0.0054 0.0109 0.0176
Schistosoma mansoni cathepsin B (C01 family) 0.0279 0.0817 0.1323
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0653 0.1998 0.2125
Loa Loa (eye worm) TYRA-2 protein 0.0054 0.0109 0.0176
Echinococcus granulosus histone lysine methyltransferase setb 0.0059 0.0127 0.0205
Plasmodium falciparum phd finger protein, putative 0.0028 0.0028 0.0076
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Echinococcus granulosus G protein coupled receptor 139 0.0054 0.0109 0.0176
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0054 0.0109 0.0109
Schistosoma mansoni hypothetical protein 0.0099 0.0252 0.0409
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0059 0.0127 0.0205
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0279 0.0817 0.1323
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0054 0.0109 0.0176
Echinococcus granulosus tm gpcr rhodopsin 0.0054 0.0109 0.0176
Schistosoma mansoni cathepsin C 0.0279 0.0817 0.1323
Loa Loa (eye worm) hypothetical protein 0.0828 0.2549 0.4127
Loa Loa (eye worm) hypothetical protein 0.0034 0.0048 0.0078
Leishmania major cathepsin L-like protease 0.1203 0.373 0.3966
Echinococcus multilocularis tumor protein p63 0.0326 0.0968 0.0968
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0046 0.0084 0.0137
Echinococcus granulosus biogenic amine 5HT receptor 0.0054 0.0109 0.0176
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0054 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0034 0.0048 0.0078
Schistosoma mansoni opsin-like receptor 0.0054 0.0109 0.0176
Loa Loa (eye worm) G-protein coupled receptor 0.0054 0.0109 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0035 0.0056
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0279 0.0817 0.2192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1203 0.373 1
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0058 0.0155
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0035 0.0056
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1979 0.6177 1
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0058 0.0814
Loa Loa (eye worm) latrophilin receptor protein 2 0.0046 0.0084 0.0137
Loa Loa (eye worm) hypothetical protein 0.1203 0.373 0.6039
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0068 0.0068
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0035 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1203 0.373 1
Onchocerca volvulus 0.0054 0.0109 0.0291
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0054 0.0109 0.0109
Giardia lamblia PHD finger protein 15 0.0028 0.0028 0.0094
Loa Loa (eye worm) intermediate filament protein 0.0052 0.0105 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0279 0.0817 0.2192
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0035 0.0056
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0035 0.0056
Brugia malayi Cathepsin L-like precursor 0.1203 0.373 0.6039
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0035 0.0056
Onchocerca volvulus 0.0056 0.0116 0.031
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0035 0.0056
Brugia malayi Latrophilin receptor protein 2 0.0046 0.0084 0.0137
Schistosoma mansoni cathepsin F (C01 family) 0.0828 0.2549 0.4127
Echinococcus multilocularis cathepsin b 0.1979 0.6177 0.6177
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0279 0.0817 0.2192
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Onchocerca volvulus 0.0054 0.0109 0.0291
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0035 0.0035
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0085 0.683
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0028 0.0076
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0034 0.0048 0.0078
Entamoeba histolytica cysteine protease, putative 0.0653 0.1998 0.5357
Echinococcus granulosus replication factor c subunit 1 0.0019 0.0000003449 0.00000055838
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0035 0.0093
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0279 0.0817 0.1323
Brugia malayi Cathepsin L-like precursor 0.0828 0.2549 0.4127
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0058 0.0061
Schistosoma mansoni ankyrin 23/unc44 0.0031 0.0036 0.0058
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0279 0.0817 0.1323
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0279 0.0817 0.2192
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0054 0.0109 0.0176
Toxoplasma gondii cathepsin CPC2 0.0279 0.0817 0.2192
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0031 0.0036 0.0059
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0145 0.0397 0.0643
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0054 0.0109 0.0176
Trypanosoma cruzi cysteine peptidase, putative 0.1203 0.373 0.3967
Brugia malayi Papain family cysteine protease containing protein 0.0653 0.1998 0.3235
Loa Loa (eye worm) hypothetical protein 0.0279 0.0817 0.1323
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0052 0.0105 0.017
Brugia malayi Papain family cysteine protease containing protein 0.1203 0.373 0.6039
Echinococcus multilocularis neuropeptide Y receptor 0.0054 0.0109 0.0109
Onchocerca volvulus 0.0054 0.0109 0.0291
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0973 0.3005 0.8056
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0058 0.0155
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0124 0.0131
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0279 0.0817 0.1323
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0034 0.0048 0.0678
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Echinococcus multilocularis peregrin 0.0028 0.0028 0.0028
Echinococcus granulosus neuropeptide receptor A26 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.0056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0035 0.0056
Schistosoma mansoni amine GPCR 0.0054 0.0109 0.0176
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0299 0.0881 0.0881
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0001 0.0002
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0035 0.0093
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0059 0.0127 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0279 0.0817 0.2192
Schistosoma mansoni inositol monophosphatase 0.0038 0.0059 0.0095
Brugia malayi hypothetical protein 0.0054 0.0109 0.0176
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.066 0.066
Brugia malayi neuropeptide F receptor 0.0054 0.0109 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1203 0.373 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Brugia malayi hypothetical protein 0.0054 0.0109 0.0176
Onchocerca volvulus 0.0037 0.0058 0.0155
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0027
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0343 0.0555
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3003 0.9402 1
Echinococcus granulosus neuropeptide s receptor 0.0054 0.0109 0.0176
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0059 0.0127 0.0127
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0059 0.0063
Brugia malayi jmjC domain containing protein 0.0092 0.023 0.0373
Giardia lamblia Cathepsin L precursor 0.0279 0.0817 0.272
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.009 0.0146
Entamoeba histolytica cysteine proteinase, putative 0.0653 0.1998 0.5357
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Onchocerca volvulus Netrin receptor homolog 0.0031 0.0036 0.0096
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0124 0.0124
Echinococcus multilocularis serotonin receptor 0.0054 0.0109 0.0109
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0279 0.0817 0.1323
Onchocerca volvulus Neuropeptide F receptor homolog 0.0054 0.0109 0.0291
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0054 0.0109 0.0176
Brugia malayi Cathepsin L-like precursor 0.1203 0.373 0.6039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0127 0.0205
Echinococcus multilocularis g protein coupled receptor 0.0054 0.0109 0.0109
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0085 0.0089
Echinococcus multilocularis cathepsin b 0.1979 0.6177 0.6177
Brugia malayi G-protein coupled receptor 0.0054 0.0109 0.0176
Schistosoma mansoni hypothetical protein 0.0039 0.0064 0.0103
Entamoeba histolytica cysteine protease, putative 0.0279 0.0817 0.2192
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0035 0.0056
Echinococcus multilocularis orexin receptor type 2 0.0054 0.0109 0.0109
Leishmania major cathepsin L-like protease 0.1203 0.373 0.3966
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0031 0.0036 0.0058
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0085 0.0089
Schistosoma mansoni intermediate filament proteins 0.0052 0.0105 0.017
Brugia malayi PHD-finger family protein 0.0028 0.0028 0.0046
Echinococcus multilocularis cpg binding protein 0.0059 0.0126 0.0126
Brugia malayi hypothetical protein 0.0054 0.0109 0.0176
Entamoeba histolytica cysteine proteinase, putative 0.0653 0.1998 0.5357
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0057 0.0092
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.0056
Brugia malayi Cathepsin L-like precursor 0.0375 0.112 0.1814
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0054 0.0109 0.0109
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0059 0.0158
Echinococcus granulosus tachykinin peptides receptor 99D 0.0054 0.0109 0.0176
Schistosoma mansoni ap endonuclease 0.002 0.0001 0.0002
Schistosoma mansoni ap endonuclease 0.002 0.0001 0.0002
Echinococcus granulosus cathepsin l1 0.0828 0.2549 0.4127
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0058 0.0155
Onchocerca volvulus 0.0279 0.0817 0.2192
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0059 0.473
Toxoplasma gondii cathepsin B 0.0973 0.3005 0.8056
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0059 0.0158
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1203 0.373 0.6039
Entamoeba histolytica hypothetical protein 0.0035 0.0049 0.0132
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0059 0.0158
Schistosoma mansoni chromosome transmission fidelity factor 0.0019 0.0000003449 0.00000055838
Brugia malayi Bromodomain containing protein 0.0028 0.0028 0.0046
Leishmania major cathepsin L-like protease 0.3003 0.9402 1
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.0239 0.0388
Onchocerca volvulus 0.0462 0.1397 0.3744
Loa Loa (eye worm) inositol-1 0.0038 0.0059 0.0095
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0109 0.0109
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0109 0.0109
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0054 0.0109 0.0291
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0000003449 0.00000092469
Onchocerca volvulus 0.0059 0.0127 0.0339
Brugia malayi hypothetical protein 0.0054 0.0109 0.0176
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.2628 0.8221 0.8744
Echinococcus multilocularis protein dispatched 1 0.0047 0.0086 0.0086
Echinococcus granulosus neuropeptide receptor 0.0054 0.0109 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0653 0.1998 0.5357
Brugia malayi G protein-coupled receptor F59B2.13 0.0054 0.0109 0.0176
Echinococcus granulosus intermediate filament protein 0.0052 0.0105 0.017
Echinococcus multilocularis allatostatin A receptor 0.0054 0.0109 0.0109
Brugia malayi cathepsin L-like precursor 0.0828 0.2549 0.4127
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0109 0.0176
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0046 0.5455
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0046 0.0085 0.683
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0054 0.0109 0.0109
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0343 0.0555
Loa Loa (eye worm) hypothetical protein 0.1979 0.6177 1
Echinococcus multilocularis Ankyrin 0.0031 0.0036 0.0036
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0028 0.0046
Onchocerca volvulus Alhambra homolog 0.0028 0.0028 0.0076
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0279 0.0817 0.272
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0028 0.0076
Loa Loa (eye worm) hypothetical protein 0.0034 0.0048 0.0078
Trichomonas vaginalis esterase, putative 0.0037 0.0058 0.0155
Echinococcus multilocularis fmrfamide receptor 0.0054 0.0109 0.0109
Schistosoma mansoni amine GPCR 0.0054 0.0109 0.0176
Brugia malayi Papain family cysteine protease containing protein 0.0279 0.0817 0.1323
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0343 0.0555
Leishmania major cathepsin L-like protease 0.3003 0.9402 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0035 0.0056
Echinococcus granulosus neuropeptides capa receptor 0.0054 0.0109 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0279 0.0817 0.2192
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0035 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3003 0.9402 1
Onchocerca volvulus 0.0052 0.0105 0.0282
Onchocerca volvulus 0.0054 0.0109 0.0291
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0035 0.0056
Brugia malayi Papain family cysteine protease containing protein 0.0653 0.1998 0.3235
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0035 0.0056
Loa Loa (eye worm) hypothetical protein 0.0046 0.0085 0.0138
Schistosoma mansoni amine GPCR 0.0054 0.0109 0.0176
Echinococcus granulosus tm gpcr rhodopsin 0.0054 0.0109 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0279 0.0817 0.2192
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0035 0.0056
Giardia lamblia Cathepsin B precursor 0.0279 0.0817 0.272
Echinococcus granulosus cysteine protease 0.0653 0.1998 0.3235
Schistosoma mansoni lamin 0.0052 0.0105 0.017
Echinococcus multilocularis neuropeptide s receptor 0.0054 0.0109 0.0109
Onchocerca volvulus 0.0054 0.0109 0.0291
Echinococcus multilocularis cathepsin L 0.0653 0.1998 0.1998
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0068 0.011
Giardia lamblia Cathepsin L precursor 0.0279 0.0817 0.272
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0343 0.0555
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0035 0.0056
Entamoeba histolytica cysteine proteinase, putative 0.1203 0.373 1
Entamoeba histolytica cysteine protease, putative 0.0653 0.1998 0.5357
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0035 0.0056
Brugia malayi larval opioid receptor 0.0054 0.0109 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0279 0.0817 0.2192
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0001 0.0002
Giardia lamblia Hypothetical protein 0.0279 0.0817 0.272
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0279 0.0817 0.2192
Echinococcus multilocularis musashi 0.0052 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0279 0.0817 0.1323
Loa Loa (eye worm) hypothetical protein 0.005 0.0097 0.0157
Echinococcus multilocularis neuropeptide receptor A26 0.0054 0.0109 0.0109
Schistosoma mansoni hypothetical protein 0.0046 0.0084 0.0137
Schistosoma mansoni hypothetical protein 0.0796 0.2448 0.3964
Entamoeba histolytica cysteine proteinase, putative 0.0828 0.2549 0.6834
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0001 0.0001
Toxoplasma gondii preprocathepsin c precursor, putative 0.0279 0.0817 0.2192
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0085 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0124 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Echinococcus granulosus cathepsin l cysteine peptidase 0.1203 0.373 0.6039
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.0056
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0042 0.0593
Echinococcus multilocularis neuropeptide Y receptor 0.0054 0.0109 0.0109
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1203 0.373 1
Trypanosoma cruzi cysteine peptidase, putative 0.3003 0.9402 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0109 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0828 0.2549 0.6834
Schistosoma mansoni hypothetical protein 0.0035 0.0049 0.008
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0093
Brugia malayi GnHR receptor homolog 0.0054 0.0109 0.0176
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0035 0.0056
Loa Loa (eye worm) G-protein coupled receptor 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0095 0.0239 0.0388
Echinococcus multilocularis cysteine protease 0.1203 0.373 0.373
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0109 0.0109
Plasmodium falciparum serine repeat antigen 6 0.0279 0.0817 0.2192
Echinococcus granulosus neuropeptides capa receptor 0.0054 0.0109 0.0176
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0092 0.023 0.0373
Entamoeba histolytica cysteine protease, putative 0.0279 0.0817 0.2192
Giardia lamblia Cysteine protease 0.0279 0.0817 0.272
Schistosoma mansoni myosin xvIII 0.0054 0.0109 0.0176
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0058 0.0814
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0001 0.0004
Brugia malayi Papain family cysteine protease containing protein 0.0279 0.0817 0.1323
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0093
Echinococcus granulosus GPCR family 2 0.0046 0.0084 0.0137
Schistosoma mansoni netrin receptor unc5 0.0031 0.0036 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1203 0.373 1
Giardia lamblia Cathepsin L precursor 0.0279 0.0817 0.272
Loa Loa (eye worm) hypothetical protein 0.0375 0.112 0.1814
Brugia malayi CHE-14 protein 0.0041 0.0068 0.011
Onchocerca volvulus 0.1203 0.373 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1203 0.373 1
Onchocerca volvulus Cathepsin F homolog 0.1203 0.373 1
Schistosoma mansoni survival motor neuron protein 0.0047 0.0086 0.014
Echinococcus granulosus neuropeptide Y receptor 0.0054 0.0109 0.0176
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1203 0.373 1
Onchocerca volvulus 0.1203 0.373 1
Schistosoma mansoni hypothetical protein 0.0046 0.0084 0.0137
Brugia malayi ecdysteroid receptor 0.003 0.0035 0.0056
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0031
Brugia malayi Cathepsin L-like precursor 0.1203 0.373 0.6039
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0124 0.1779
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0046 0.0084 0.0137
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Onchocerca volvulus 0.0054 0.0109 0.0291
Echinococcus multilocularis GPCR, family 2 0.0046 0.0084 0.0084
Giardia lamblia Cathepsin L-like protease 0.0279 0.0817 0.272
Toxoplasma gondii ABC1 family protein 0.0037 0.0058 0.0155
Schistosoma mansoni neuropeptide F-like receptor 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Brugia malayi Pre-SET motif family protein 0.0059 0.0127 0.0205
Entamoeba histolytica cysteine protease, putative 0.0279 0.0817 0.2192
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0279 0.0817 0.2192
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1203 0.373 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3003 0.9402 1
Echinococcus granulosus expressed conserved protein 0.0089 0.0221 0.0358
Plasmodium vivax serine-repeat antigen (SERA) 0.0279 0.0817 0.2192
Echinococcus granulosus orexin receptor type 2 0.0054 0.0109 0.0176
Schistosoma mansoni hypothetical protein 0.0176 0.0495 0.0802
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0054 0.0109 0.0176
Schistosoma mansoni cpg binding protein 0.0056 0.0116 0.0187
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1203 0.373 1
Echinococcus granulosus allatostatin A receptor 0.0054 0.0109 0.0176
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.0368 0.0368
Brugia malayi Dopamine receptor 0.0054 0.0109 0.0176
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1979 0.6177 1
Plasmodium vivax unspecified product 0.0653 0.1998 0.5357
Echinococcus granulosus peptide allatostatin:somatostatin 0.0054 0.0109 0.0176
Onchocerca volvulus 0.0054 0.0109 0.0291
Brugia malayi Serotonin receptor 0.0054 0.0109 0.0176
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0059 0.0063
Giardia lamblia Cysteine protease 0.0279 0.0817 0.272
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3003 0.9402 1
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.2041 0.3304
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0058 0.0093
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0124 0.0202
Echinococcus granulosus cathepsin l1 0.1203 0.373 0.6039
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0653 0.1998 0.3235
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0049 0.008
Schistosoma mansoni lamin 0.0052 0.0105 0.017
Schistosoma mansoni growth hormone secretagogue receptor 0.0054 0.0109 0.0176
Schistosoma mansoni thyroid hormone receptor 0.003 0.0035 0.0056
Brugia malayi TAR-binding protein 0.0128 0.0343 0.0555
Schistosoma mansoni neuropeptide receptor 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0034 0.0048 0.0078
Loa Loa (eye worm) hypothetical protein 0.0279 0.0817 0.1323
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0828 0.2549 0.6834
Echinococcus granulosus cathepsin L 0.0279 0.0817 0.1323
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0085 0.0089
Trichomonas vaginalis set domain proteins, putative 0.0462 0.1396 0.3743
Entamoeba histolytica cysteine proteinase 1, putative 0.0653 0.1998 0.5357
Loa Loa (eye worm) hypothetical protein 0.0375 0.112 0.1814
Loa Loa (eye worm) TAR-binding protein 0.0128 0.0343 0.0555
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0109 0.0176
Loa Loa (eye worm) RNA binding protein 0.0128 0.0343 0.0555
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0279 0.0817 0.2192
Entamoeba histolytica cysteine protease, putative 0.0653 0.1998 0.5357
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0035 0.0035
Echinococcus granulosus somatostatin receptor 0.0054 0.0109 0.0176
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0001 0.0001
Plasmodium falciparum serine repeat antigen 5 0.0279 0.0817 0.2192
Brugia malayi RNA binding protein 0.0128 0.0343 0.0555
Brugia malayi putative neuropeptide receptor NPR1 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.0056
Echinococcus granulosus 7TM GPCR rhodopsin 0.0054 0.0109 0.0176
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0063 0.0102
Echinococcus multilocularis g-protein coupled receptor 0.0054 0.0109 0.0109
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0058 0.4632
Schistosoma mansoni hypothetical protein 0.0054 0.0109 0.0176
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3003 0.9402 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0109 0.0109
Echinococcus granulosus cathepsin L cysteine protease 0.0653 0.1998 0.3235
Brugia malayi ORL1-like opioid receptor 0.0054 0.0109 0.0176
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0279 0.0817 0.2192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0279 0.0817 0.2192
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0085 0.0138
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0046
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0046 0.0084 0.0084
Echinococcus multilocularis neuropeptides capa receptor 0.0054 0.0109 0.0109
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0973 0.3005 0.3196
Plasmodium vivax acyl-CoA synthetase, putative 0.0034 0.0048 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0035 0.0056
Echinococcus multilocularis dro:myosuppressin receptor 0.0054 0.0109 0.0109
Mycobacterium leprae Probable lipase LipE 0.0037 0.0058 0.6782
Schistosoma mansoni neuropeptide receptor 0.0054 0.0109 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0279 0.0817 0.2192
Echinococcus granulosus peregrin 0.0028 0.0028 0.0046
Toxoplasma gondii histone lysine methyltransferase SET1 0.0108 0.028 0.0751
Schistosoma mansoni hypothetical protein 0.0054 0.0109 0.0176
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0279 0.0817 0.2192
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0059 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1203 0.373 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.0056
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0054 0.0109 0.0176
Echinococcus granulosus cathepsin b 0.1979 0.6177 1
Echinococcus multilocularis cathepsin L 0.0279 0.0817 0.0817
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0035 0.0056
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0036 0.0058
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0035 0.0056
Trypanosoma cruzi cysteine peptidase, putative 0.0653 0.1998 0.2125
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0058 0.0814
Entamoeba histolytica cysteine proteinase, putative 0.0653 0.1998 0.5357
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0279 0.0817 0.2192
Plasmodium vivax SET domain protein, putative 0.0059 0.0127 0.0339
Schistosoma mansoni amine GPCR 0.0054 0.0109 0.0176
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0279 0.0817 0.1323
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0279 0.0817 0.2192
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Trypanosoma brucei cysteine peptidase C (CPC) 0.0973 0.3005 0.3196
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0001 0.0002
Plasmodium falciparum serine repeat antigen 9 0.0279 0.0817 0.2192
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.0056
Echinococcus granulosus netrin receptor unc 5 0.0031 0.0036 0.0058
Schistosoma mansoni hypothetical protein 0.0028 0.0028 0.0046
Echinococcus granulosus death domain containing protein 0.0031 0.0036 0.0058
Giardia lamblia Cysteine protease 0.0279 0.0817 0.272
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0973 0.3005 0.4865
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0127 0.0205
Entamoeba histolytica cysteine protease, putative 0.0653 0.1998 0.5357
Brugia malayi Cathepsin L-like precursor 0.0828 0.2549 0.4127
Loa Loa (eye worm) hypothetical protein 0.0052 0.0102 0.0165
Entamoeba histolytica cysteine protease, putative 0.0653 0.1998 0.5357
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0375 0.112 0.1814
Mycobacterium ulcerans hypothetical protein 0.0037 0.0058 0.4632
Leishmania major hypothetical protein, conserved 0.0037 0.0058 0.006
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0054 0.0109 0.0109
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.0368 0.0596
Toxoplasma gondii cathepsin CPC1 0.0279 0.0817 0.2192
Onchocerca volvulus Cathepsin L homolog 0.1203 0.373 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Loa Loa (eye worm) fibroinase 0.1203 0.373 0.6039
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0054 0.0109 0.0109
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0109 0.0176
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0001 0.0001
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0092 0.023 0.023
Mycobacterium tuberculosis Conserved protein 0.0037 0.0058 0.0814
Entamoeba histolytica cysteine protease, putative 0.0653 0.1998 0.5357
Brugia malayi Melatonin receptor type 1A 0.0054 0.0109 0.0176
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0068 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0109 0.0176
Plasmodium vivax serine-repeat antigen (SERA) 0.0279 0.0817 0.2192
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0035 0.0056
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0046 0.0084 0.0084
Echinococcus multilocularis g protein coupled receptor 0.0054 0.0109 0.0109
Onchocerca volvulus 0.0048 0.009 0.0242
Giardia lamblia Cathepsin B precursor 0.0973 0.3005 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0054 0.0109 0.0176
Echinococcus granulosus g-protein coupled receptor 0.0054 0.0109 0.0176
Schistosoma mansoni amine GPCR 0.0054 0.0109 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0279 0.0817 0.2192
Brugia malayi cathepsin F-like cysteine proteinase 0.0375 0.112 0.1814
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0653 0.1998 0.2125
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0279 0.0817 0.2192
Brugia malayi beta-lactamase family protein 0.0037 0.0058 0.0093
Echinococcus granulosus hypothetical protein 0.0054 0.0109 0.0176
Loa Loa (eye worm) melatonin receptor type 1A 0.0054 0.0109 0.0176
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.0239 0.0642
Onchocerca volvulus 0.0052 0.0105 0.0282
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0049 0.008
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0035 0.0056
Onchocerca volvulus 0.1203 0.373 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0056 0.0116 0.0188
Brugia malayi intermediate filament protein 0.0052 0.0105 0.017
Brugia malayi hypothetical protein 0.0035 0.0049 0.008
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0049 0.0049
Echinococcus multilocularis replication factor c subunit 1 0.0019 0.0000003449 0.0000003449
Entamoeba histolytica cysteine proteinase, putative 0.1203 0.373 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1979 0.6177 0.657
Loa Loa (eye worm) cysteine protease 0.1203 0.373 0.6039
Brugia malayi AKH receptor 0.0054 0.0109 0.0176
Brugia malayi cathepsin F-like cysteine proteinase 0.0279 0.0817 0.1323
Brugia malayi Death domain containing protein 0.0031 0.0036 0.0058
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0109 0.0109
Echinococcus multilocularis protein patched 0.0041 0.0068 0.0068
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0058 0.4632
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0058 0.0155
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0034 0.0048 0.3877
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3003 0.9402 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0042 0.0593
Echinococcus granulosus fmrfamide receptor 0.0054 0.0109 0.0176
Echinococcus granulosus nuclear factor of activated T cells 5 0.0299 0.0881 0.1427
Loa Loa (eye worm) beta-lactamase 0.0037 0.0058 0.0093
Schistosoma mansoni neuropeptide F-like receptor 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0375 0.112 0.1814
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0054 0.0109 0.0176
Echinococcus granulosus cathepsin L 0.0653 0.1998 0.3235
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0054 0.0109 0.0176
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0025 0.0019 0.0019
Plasmodium falciparum serine repeat antigen 1 0.0279 0.0817 0.2192
Brugia malayi G-protein coupled receptor 0.0054 0.0109 0.0176
Trypanosoma cruzi cysteine peptidase, putative 0.3003 0.9402 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0054 0.0109 0.0176
Echinococcus multilocularis lamin dm0 0.0052 0.0105 0.0105
Brugia malayi Serotonin receptor 0.0054 0.0109 0.0176
Echinococcus multilocularis netrin receptor unc 5 0.0031 0.0036 0.0036
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0085 0.0228
Onchocerca volvulus 0.0047 0.0086 0.0232
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.0239 0.0388
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0035 0.0056
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0279 0.0817 0.272
Entamoeba histolytica cysteine protease, putative 0.0653 0.1998 0.5357
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0085 0.683
Loa Loa (eye worm) hypothetical protein 0.0046 0.0085 0.0138
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0059 0.0158
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0054 0.0109 0.0176
Mycobacterium tuberculosis Conserved protein 0.0037 0.0058 0.0814
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0145 0.0397 0.0643
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0279 0.0817 0.2192
Schistosoma mansoni neuropeptide receptor 0.0054 0.0109 0.0176
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0279 0.0817 0.2192
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0054 0.0109 0.0176
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.0239 0.0239
Schistosoma mansoni opsin-like receptor 0.0054 0.0109 0.0176
Onchocerca volvulus 0.0054 0.0109 0.0291
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0109 0.0176
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0128 0.0343 0.0555
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0058 0.0058
Giardia lamblia Cathepsin L precursor 0.0279 0.0817 0.272
Echinococcus multilocularis somatostatin receptor 0.0054 0.0109 0.0109
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0054 0.0109 0.0109
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0085 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0035 0.0056
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0279 0.0817 0.2192
Echinococcus granulosus tm gpcr rhodopsin 0.0054 0.0109 0.0176
Echinococcus granulosus cpg binding protein 0.0059 0.0126 0.0204
Brugia malayi sulfakinin receptor protein 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0099 0.0252 0.0409
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0109 0.0109
Echinococcus multilocularis neuropeptide receptor 0.0054 0.0109 0.0109
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0035 0.0056
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0054 0.0109 0.0109
Onchocerca volvulus 0.0037 0.0058 0.0155
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0279 0.0817 0.1323
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0054 0.0109 0.0176
Plasmodium vivax vivapain-2 0.1203 0.373 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0124 1
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0058 0.6782
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0279 0.0817 0.2192
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0028 0.0046
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0279 0.0817 0.2192
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0054 0.0109 0.0109
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0109 0.0176
Giardia lamblia Cathepsin B precursor 0.0279 0.0817 0.272
Loa Loa (eye worm) ctsf protein 0.1203 0.373 0.6039
Mycobacterium ulcerans lipase LipD 0.0037 0.0058 0.4632
Mycobacterium ulcerans hypothetical protein 0.0046 0.0085 0.683
Schistosoma mansoni biogenic amine receptor 0.0054 0.0109 0.0176
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0057 0.0092
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0057 0.0092
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0035 0.0093
Toxoplasma gondii exonuclease III APE 0.002 0.0001 0.0003
Giardia lamblia Cathepsin B precursor 0.0973 0.3005 1
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0085 0.0138
Onchocerca volvulus 0.003 0.0035 0.0093
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0001 0.0003
Echinococcus granulosus g protein coupled receptor 0.0054 0.0109 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0035 0.0056
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0124 0.0334
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Entamoeba histolytica cysteine protease, putative 0.0279 0.0817 0.2192
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0001 0.0001
Onchocerca volvulus 0.0054 0.0109 0.0291
Echinococcus multilocularis lamin 0.0052 0.0105 0.0105
Schistosoma mansoni patched 1 0.0041 0.0068 0.011
Entamoeba histolytica cysteine protease, putative 0.0279 0.0817 0.2192
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0058 0.0093
Plasmodium vivax unspecified product 0.0279 0.0817 0.2192
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0279 0.0817 0.2192
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0086 0.014
Schistosoma mansoni inositol monophosphatase 0.0038 0.0059 0.0095
Giardia lamblia Cathepsin B precursor 0.0279 0.0817 0.272
Schistosoma mansoni hypothetical protein 0.0046 0.0084 0.0137
Schistosoma mansoni nuclear hormone receptor 0.003 0.0035 0.0056
Loa Loa (eye worm) hypothetical protein 0.0041 0.0068 0.011
Schistosoma mansoni opsin-like receptor 0.0054 0.0109 0.0176
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0058 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1203 0.373 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0054 0.0109 0.0176
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0054 0.0109 0.0176
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0054 0.0109 0.0109
Brugia malayi RNA recognition motif domain containing protein 0.0128 0.0343 0.0555
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0035 0.0056
Brugia malayi hypothetical protein 0.0054 0.0109 0.0176
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0109 0.0176
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0058 0.0155
Entamoeba histolytica cysteine protease, putative 0.0653 0.1998 0.5357
Echinococcus multilocularis sex peptide receptor 0.0054 0.0109 0.0109
Schistosoma mansoni thyroid hormone receptor 0.003 0.0035 0.0056
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0343 0.0555
Onchocerca volvulus 0.0054 0.0109 0.0291
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0244 0.0395
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0109 0.0176
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0035 0.0035
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.0109 0.0176
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0279 0.0817 0.2192
Brugia malayi cathepsin B-like cysteine proteinase 0.1979 0.6177 1
Echinococcus multilocularis geminin 0.0176 0.0495 0.0495
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0058 0.0093
Plasmodium falciparum acyl-CoA synthetase 0.0034 0.0048 0.0129
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0028 0.0028
Brugia malayi latrophilin 2 splice variant baaae 0.0099 0.0252 0.0409
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0109 0.0176
Onchocerca volvulus 0.1203 0.373 1
Schistosoma mansoni hypothetical protein 0.0039 0.0064 0.0103
Echinococcus granulosus Ankyrin 0.0031 0.0036 0.0059
Brugia malayi hypothetical protein 0.0054 0.0109 0.0176
Loa Loa (eye worm) cathepsin B 0.0973 0.3005 0.4865
Leishmania major cathepsin L-like protease 0.1203 0.373 0.3966
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3003 0.9402 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0035 0.0056
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Brugia malayi Cathepsin L-like cysteine proteinase 0.0828 0.2549 0.4127
Brugia malayi cathepsin Z-like cysteine proteinase 0.0279 0.0817 0.1323
Giardia lamblia Cathepsin B precursor 0.0279 0.0817 0.272
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0054 0.0109 0.0176
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0046 0.0085 0.683
Entamoeba histolytica hypothetical protein 0.0035 0.0049 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1203 0.373 1
Schistosoma mansoni hypothetical protein 0.0054 0.0109 0.0176
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0059 0.0127 0.0339
Brugia malayi Dopamine receptor protein 2 0.0054 0.0109 0.0176
Echinococcus multilocularis neuropeptide receptor 0.0054 0.0109 0.0109
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0028 0.0046
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0035 0.0056
Echinococcus multilocularis tar DNA binding protein 0.0128 0.0343 0.0343
Schistosoma mansoni cpg binding protein 0.0059 0.0126 0.0204
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0653 0.1998 0.3235
Schistosoma mansoni biogenic amine receptor 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0059 0.0127 0.0205
Onchocerca volvulus 0.0046 0.0085 0.0228
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0123 0.0199
Onchocerca volvulus 0.0054 0.0109 0.0291
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0001 0.0003
Giardia lamblia Cathepsin B precursor 0.0279 0.0817 0.272
Onchocerca volvulus Cathepsin L homolog 0.0279 0.0817 0.2192
Onchocerca volvulus 0.0054 0.0109 0.0291
Schistosoma mansoni cpg binding protein 0.0059 0.0126 0.0204
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0109 0.0109
Brugia malayi Inositol-1 0.0038 0.0059 0.0095
Schistosoma mansoni cathepsin s 0.0375 0.112 0.1814
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0054 0.0109 0.0176
Echinococcus granulosus FTZ F1 alpha 0.003 0.0035 0.0056
Entamoeba histolytica cysteine protease, putative 0.0653 0.1998 0.5357
Schistosoma mansoni alpha-1 adrenergic receptor 0.0054 0.0109 0.0176
Toxoplasma gondii ATPase, AAA family protein 0.0019 0.0000003449 0.00000092469
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0035 0.0035
Trypanosoma cruzi cysteine proteinase, putative 0.0653 0.1998 0.2125
Entamoeba histolytica cysteine proteinase 2 0.0653 0.1998 0.5357
Schistosoma mansoni hypothetical protein 0.0176 0.0495 0.0802
Loa Loa (eye worm) neuropeptide F receptor 0.0054 0.0109 0.0176
Echinococcus granulosus dnaJ subfamily B 0.0796 0.2448 0.3964
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0279 0.0817 0.272
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0653 0.1998 0.5357
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0046 0.0084 0.0137
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0059 0.0095
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176
Loa Loa (eye worm) hypothetical protein 0.0228 0.066 0.1068
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0042 0.0593
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0085 0.1209
Loa Loa (eye worm) hypothetical protein 0.0054 0.0109 0.0176

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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