Detailed information for compound 1537785

Basic information

Technical information
  • TDR Targets ID: 1537785
  • Name: 6-[2-(azepan-1-yl)-2-oxoethyl]-8-chloropyrido [2,3-b][1,5]benzoxazepin-5-one
  • MW: 385.844 | Formula: C20H20ClN3O3
  • H donors: 0 H acceptors: 3 LogP: 3.17 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc2c(c1)N(CC(=O)N1CCCCCC1)C(=O)c1c(O2)nccc1
  • InChi: 1S/C20H20ClN3O3/c21-14-7-8-17-16(12-14)24(13-18(25)23-10-3-1-2-4-11-23)20(26)15-6-5-9-22-19(15)27-17/h5-9,12H,1-4,10-11,13H2
  • InChiKey: SSOKAOABPHAFKD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-[2-(azepan-1-yl)-2-oxo-ethyl]-8-chloro-pyrido[2,3-b][1,5]benzoxazepin-5-one
  • 6-[2-(1-azepanyl)-2-oxoethyl]-8-chloro-5-pyrido[2,3-b][1,5]benzoxazepinone
  • 6-[2-(azepan-1-yl)-2-keto-ethyl]-8-chloro-pyrido[2,3-b][1,5]benzoxazepin-5-one

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus neuropeptide receptor 0.0028 0.0224 0.0224
Toxoplasma gondii sugar transporter ST1 0.003 0.0239 0.0383
Echinococcus multilocularis General substrate transporter 0.0182 0.1849 0.1849
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.0019 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0244 0.0777
Plasmodium vivax importin-beta 2, putative 0.0028 0.0226 0.0239
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0093 0.0093
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0009 0.0016 0.0066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Onchocerca volvulus 0.0028 0.0224 0.0909
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0007 0.0002 0.0006
Plasmodium falciparum glutathione reductase 0.0048 0.043 0.0456
Brugia malayi hypothetical protein 0.0028 0.0224 0.067
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0028 0.0224 0.0224
Trypanosoma brucei glucose transporter, putative 0.0066 0.0619 0.8747
Brugia malayi neuropeptide F receptor 0.0028 0.0224 0.067
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0007 0.0002 0.0006
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0224 0.0224
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0224 0.0712
Onchocerca volvulus 0.0028 0.0224 0.0909
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0046 0.0757
Loa Loa (eye worm) latrophilin receptor protein 2 0.0096 0.0938 0.281
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0012 0.0051 0.0151
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0051 0.0711
Onchocerca volvulus 0.0239 0.2458 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0304 0.4291
Brugia malayi hypothetical protein 0.0028 0.0224 0.067
Plasmodium falciparum calcium-dependent protein kinase 4 0.0065 0.0611 0.0647
Brugia malayi MH2 domain containing protein 0.0234 0.2401 0.7195
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0428 0.1282
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.061 0.061
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0028 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Schistosoma mansoni retinoic acid receptor RXR 0.0007 0.0002 0.0007
Entamoeba histolytica hypothetical protein 0.0047 0.0424 0.6953
Plasmodium falciparum protein kinase 7 0.0598 0.625 0.663
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0189 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0007 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Onchocerca volvulus 0.003 0.0239 0.0974
Echinococcus granulosus General substrate transporter 0.0182 0.1849 0.1849
Schistosoma mansoni hypothetical protein 0.0096 0.0938 0.2989
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0078 0.0078
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.01 0.3278
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0065 0.061 0.1828
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0224 0.0224
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0189 0.0768
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.01 0.1469
Schistosoma mansoni hypothetical protein 0.0048 0.0428 0.1364
Loa Loa (eye worm) MH2 domain-containing protein 0.0234 0.2401 0.7195
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0224 0.0712
Onchocerca volvulus 0.0007 0.0002 0.0008
Onchocerca volvulus 0.003 0.0239 0.0974
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0007 0.0002 0.0006
Onchocerca volvulus 0.0028 0.0224 0.0909
Brugia malayi hypothetical protein 0.0323 0.3337 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0007 0.0002 0.0007
Onchocerca volvulus 0.0028 0.0224 0.0909
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0226 0.3185
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0028 0.0224 0.0712
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0146 0.0438
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Mycobacterium ulcerans putative regulatory protein 0.0071 0.0677 1
Schistosoma mansoni ran 0.0021 0.0146 0.0466
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Schistosoma mansoni neuropeptide f receptor 76f 0.0028 0.0224 0.0712
Onchocerca volvulus 0.003 0.0244 0.0991
Plasmodium vivax threonine--tRNA ligase, putative 0.0012 0.0051 0.0053
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0009 0.0019 0.002
Trypanosoma brucei glucose transporter 2A 0.0066 0.0619 0.8747
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.01 0.1406
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Schistosoma mansoni biogenic amine receptor 0.0028 0.0224 0.0712
Brugia malayi Sugar transporter family protein 0.0212 0.2163 0.6482
Chlamydia trachomatis proline--tRNA ligase 0.0022 0.0162 0.3811
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0619 0.2519
Echinococcus granulosus neuropeptide receptor 0.0028 0.0224 0.0224
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.043 0.043
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0108 0.1521
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0224 0.0224
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.01 0.0106
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0146 0.2062
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0224 0.0224
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0224 0.067
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Schistosoma mansoni steroid hormone receptor ad4bp 0.0007 0.0002 0.0007
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0096 0.0938 0.0938
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0012 0.0051 0.0151
Brugia malayi Sugar transporter family protein 0.003 0.0239 0.0717
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0065 0.0611 0.0647
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0028 0.0224 0.0712
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0028 0.0224 0.0712
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.0019 0.0019
Plasmodium vivax lysine--tRNA ligase, putative 0.0047 0.0424 0.045
Echinococcus multilocularis dro:myosuppressin receptor 0.0028 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Brugia malayi putative neuropeptide receptor NPR1 0.0028 0.0224 0.067
Loa Loa (eye worm) hypothetical protein 0.0025 0.0189 0.0566
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.048 0.0768
Leishmania major hypothetical protein, conserved 0.0011 0.0036 0.0504
Brugia malayi hypothetical protein 0.0028 0.0224 0.067
Echinococcus granulosus lamin 0.0026 0.0201 0.0201
Loa Loa (eye worm) hypothetical protein 0.0012 0.0051 0.0151
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.01 0.01
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0224 0.0224
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0189 0.0768
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0028 0.0224 0.0712
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0058 0.0058
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0007 0.0002 0.0002
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.0051 0.0125
Schistosoma mansoni lamin 0.0026 0.0201 0.0642
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Echinococcus granulosus FTZ F1 alpha 0.0007 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.003 0.0239 0.7879
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0006
Echinococcus multilocularis Smad4 0.0016 0.0093 0.0093
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0224 0.0224
Echinococcus multilocularis G protein coupled receptor 139 0.0028 0.0224 0.0224
Schistosoma mansoni neuropeptide receptor 0.0028 0.0224 0.0712
Onchocerca volvulus Protein ultraspiracle homolog 0.0007 0.0002 0.0008
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0028 0.0224 0.067
Entamoeba histolytica hypothetical protein 0.0023 0.0169 0.2761
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0303 0.3127 0.9369
Giardia lamblia Sgs1 DNA helicase, putative 0.0009 0.0019 0.0041
Toxoplasma gondii lysine-tRNA ligase 0.0047 0.0424 0.0679
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.01 0.1406
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.1077 0.8919
Trypanosoma cruzi glucose transporter, putative 0.003 0.0239 0.3381
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0053 0.0159
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.0051 0.0711
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0224 0.0224
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.043 0.3477
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0047 0.0424 0.5996
Schistosoma mansoni hypothetical protein 0.0028 0.0224 0.0712
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.003 0.0239 0.3381
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.061 0.1945
Loa Loa (eye worm) hypothetical protein 0.0017 0.0106 0.0319
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0224 0.0712
Brugia malayi MH2 domain containing protein 0.0016 0.0093 0.028
Plasmodium falciparum calcium-dependent protein kinase 2 0.0065 0.0611 0.0647
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0189 0.2668
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0007 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.01 0.1406
Echinococcus granulosus g protein coupled receptor 0.0028 0.0224 0.0224
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0063 0.0596 0.2427
Brugia malayi glycyl-tRNA synthetase 0.0012 0.0051 0.0151
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0029 0.0232 0.3273
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0224 0.0224
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.01 0.1469
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0108 0.0108
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.0019 0.0019
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0189 0.0189
Schistosoma mansoni inositol monophosphatase 0.0036 0.0304 0.0968
Echinococcus granulosus Ankyrin 0.0015 0.008 0.008
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.01 0.1406
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Brugia malayi MH1 domain containing protein 0.0009 0.0018 0.0054
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0028 0.0224 0.067
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.01 0.1406
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0093 0.028
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0007 0.0002 0.0002
Brugia malayi Pre-SET motif family protein 0.021 0.2149 0.6439
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0304 0.1236
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0006
Echinococcus granulosus smad 0.0016 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0026 0.0196 0.0588
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0063 0.0596 0.0596
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0224 0.0712
Schistosoma mansoni thyroid hormone receptor 0.0007 0.0002 0.0007
Brugia malayi major facilitator superfamily protein 0.003 0.0239 0.0717
Onchocerca volvulus 0.0028 0.0224 0.0909
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0239 0.0717
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.01 0.1406
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0007 0.0002 0.0006
Brugia malayi Smad1 0.0016 0.0093 0.028
Schistosoma mansoni hypothetical protein 0.0096 0.0938 0.2989
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0264 0.1949
Brugia malayi hypothetical protein 0.0052 0.048 0.1438
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0304 0.0486
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0349 0.2796
Schistosoma mansoni smad1 5 8 and 0.0016 0.0093 0.0297
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Trypanosoma brucei glucose transporter, putative 0.0066 0.0619 0.8747
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0189 0.0768
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0046 0.0653
Echinococcus multilocularis geminin 0.0167 0.1693 0.1693
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0239 0.0974
Brugia malayi GnHR receptor homolog 0.0028 0.0224 0.067
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.01 0.2346
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0074 0.0708 0.1132
Loa Loa (eye worm) hypoxia-induced factor 1 0.0298 0.3073 0.9208
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.1077 0.8919
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0028 0.0224 0.067
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0056
Echinococcus multilocularis thyroid hormone receptor alpha 0.0007 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Brugia malayi Tachykinin-like peptides receptor 99D 0.0028 0.0224 0.067
Brugia malayi Cam kinase protein 1 0.0065 0.061 0.1828
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.01 0.1406
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0304 0.4291
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Echinococcus multilocularis FTZ F1 alpha 0.0007 0.0002 0.0002
Trypanosoma cruzi sugar transporter, putative 0.003 0.0239 0.3381
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Schistosoma mansoni glucose transporter 0.003 0.0239 0.0763
Schistosoma mansoni threonyl-tRNA synthetase 0.0007 0 0.0001
Plasmodium falciparum glutathione reductase 0.0017 0.01 0.0106
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0619 0.8747
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0212 0.2163 0.2163
Loa Loa (eye worm) hypothetical protein 0.0013 0.0058 0.0174
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0224 0.0224
Toxoplasma gondii protein kinase, putative 0.0598 0.625 1
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0189 0.0566
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0007 0.0002 0.0006
Schistosoma mansoni intermediate filament proteins 0.0026 0.0201 0.0642
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0224 0.0224
Onchocerca volvulus 0.0028 0.0224 0.0909
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.01 0.1406
Echinococcus granulosus Threonyl tRNA synthetase C 0.0012 0.0051 0.0051
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0224 0.0224
Brugia malayi PAS domain containing protein 0.0096 0.0942 0.2822
Mycobacterium leprae Possible regulatory protein 0.0025 0.0189 0.1308
Loa Loa (eye worm) hypothetical protein 0.0015 0.0078 0.0234
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0079 0.0083
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0349 0.2676
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.061 0.061
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0007 0.0002 0.0006
Brugia malayi G-protein coupled receptor 0.0028 0.0224 0.067
Brugia malayi AKH receptor 0.0028 0.0224 0.067
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0028 0.0224 0.067
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0065 0.061 0.061
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.01 0.1406
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0224 0.0712
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0025 0.0189 0.445
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.048 0.0509
Brugia malayi MH1 domain containing protein 0.0016 0.0093 0.028
Brugia malayi Steroid receptor seven-up type 2 0.0007 0.0002 0.0006
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Schistosoma mansoni glycyl-tRNA synthetase 0.0012 0.0051 0.0161
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0224 0.0712
Loa Loa (eye worm) hypothetical protein 0.0009 0.0018 0.0054
Onchocerca volvulus 0.0028 0.0224 0.0909
Onchocerca volvulus 0.0028 0.0224 0.0909
Schistosoma mansoni lamin 0.0026 0.0201 0.0642
Schistosoma mansoni biogenic amine receptor 0.0028 0.0224 0.0712
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0619 0.8747
Treponema pallidum prolyl-tRNA synthetase 0.0022 0.0162 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Toxoplasma gondii thioredoxin reductase 0.0048 0.043 0.0688
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0093 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Brugia malayi latrophilin 2 splice variant baaae 0.0207 0.2114 0.6333
Trichomonas vaginalis conserved hypothetical protein 0.0212 0.2163 0.8807
Echinococcus multilocularis neuropeptide s receptor 0.0952 1 1
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.0051 0.008
Entamoeba histolytica Ran family GTPase 0.0021 0.0146 0.2391
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0009 0.0016 0.0066
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.048 0.0509
Brugia malayi hypothetical protein 0.0034 0.0283 0.0848
Loa Loa (eye worm) hypothetical protein 0.0052 0.048 0.1438
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0065 0.0611 0.0976
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0078 0.0078
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.048 0.6782
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0078 0.0078
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0036 0.0504
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0028 0.0224 0.0224
Loa Loa (eye worm) sugar transporter 0.0212 0.2163 0.6482
Onchocerca volvulus 0.003 0.0239 0.0974
Brugia malayi G protein-coupled receptor 0.0028 0.0224 0.067
Plasmodium falciparum calcium-dependent protein kinase 3 0.0065 0.0611 0.0647
Echinococcus multilocularis lysyl tRNA synthetase 0.0047 0.0424 0.0424
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0146 0.0155
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0053 0.0159
Echinococcus granulosus lysyl tRNA synthetase 0.0047 0.0424 0.0424
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.1206 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.0708 1
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0108 0.0323
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.01 0.1406
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0007 0.0002 0.0002
Giardia lamblia Prolyl-tRNA synthetase 0.0063 0.0596 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0028 0.0224 0.067
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Echinococcus multilocularis lamin dm0 0.0026 0.0201 0.0201
Brugia malayi major facilitator superfamily protein 0.003 0.0239 0.0717
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.048 0.0509
Brugia malayi hypothetical protein 0.0028 0.0224 0.067
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0224 0.067
Brugia malayi larval opioid receptor 0.0028 0.0224 0.067
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.008 0.0254
Schistosoma mansoni coup transcription factor 0.0007 0.0002 0.0007
Brugia malayi neuropeptide F receptor 0.0028 0.0224 0.067
Entamoeba histolytica protein kinase, putative 0.0065 0.061 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Brugia malayi lysyl-tRNA synthetase 0.0047 0.0424 0.1271
Loa Loa (eye worm) hypothetical protein 0.0047 0.0424 0.1271
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0065 0.061 0.1828
Brugia malayi Melatonin receptor type 1A 0.0028 0.0224 0.067
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.0019 0.0019
Schistosoma mansoni DNA helicase recq1 0.0009 0.0019 0.006
Echinococcus granulosus bloom syndrome protein 0.0022 0.0153 0.0153
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0096 0.0938 0.281
Mycobacterium ulcerans sulfatase 0.0009 0.0016 0.0238
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0153 0.0457
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0189 0.0768
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0224 0.0712
Echinococcus multilocularis sodium channel protein 0.004 0.0344 0.0344
Schistosoma mansoni ran 0.0021 0.0146 0.0466
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0007 0.0002 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0239 0.0974
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.3137 0.94
Loa Loa (eye worm) hypothetical protein 0.0063 0.0596 0.1787
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0007 0.0002 0.0007
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0596 0.1901
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.0363 0.1476
Brugia malayi ORL1-like opioid receptor 0.0028 0.0224 0.067
Plasmodium vivax SET domain protein, putative 0.003 0.0244 0.0258
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Loa Loa (eye worm) follicle stimulating hormone receptor 0.025 0.2575 0.7716
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0224 0.0224
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0108 0.0323
Plasmodium vivax glycine--tRNA ligase, putative 0.0012 0.0051 0.0053
Trypanosoma brucei glucose transporter, putative 0.0066 0.0619 0.8747
Loa Loa (eye worm) Smad1 0.0016 0.0093 0.028
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.0051 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0224 0.0712
Schistosoma mansoni hypothetical protein 0.0167 0.1693 0.5397
Mycobacterium ulcerans arylsulfatase AtsD 0.0009 0.0016 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Plasmodium vivax hexose transporter 0.0212 0.2163 0.2295
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.0051 0.0205
Schistosoma mansoni hypothetical protein 0.0024 0.0174 0.0554
Brugia malayi sulfakinin receptor protein 0.0028 0.0224 0.067
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.01 0.01
Schistosoma mansoni thyroid hormone receptor 0.0007 0.0002 0.0007
Schistosoma mansoni DNA helicase recq5 0.0009 0.0019 0.006
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0028 0.0224 0.0224
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0046 0.0653
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0028 0.0224 0.0224
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0304 0.1236
Echinococcus multilocularis smad 0.0016 0.0093 0.0093
Plasmodium falciparum calcium-dependent protein kinase 5 0.0065 0.0611 0.0647
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.1077 0.8901
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0146 0.0146
Brugia malayi ecdysteroid receptor 0.0007 0.0002 0.0006
Plasmodium falciparum protein kinase 6 0.0898 0.9426 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0093 0.028
Echinococcus granulosus neuropeptide FF receptor 2 0.0028 0.0224 0.0224
Leishmania major threonyl-tRNA synthetase, putative 0.0012 0.0051 0.0711
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0212 0.2163 0.2163
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0189 0.0768
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Onchocerca volvulus 0.0028 0.0224 0.0909
Brugia malayi Sugar transporter family protein 0.003 0.0239 0.0717
Schistosoma mansoni neuropeptide receptor 0.0028 0.0224 0.0712
Brugia malayi hypothetical protein 0.003 0.0239 0.0717
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0108 0.0769
Brugia malayi Latrophilin receptor protein 2 0.0096 0.0938 0.281
Brugia malayi Dopamine receptor protein 1 0.0028 0.0224 0.067
Echinococcus granulosus 7TM GPCR rhodopsin 0.0028 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0065 0.0611 0.0976
Trichomonas vaginalis sugar transport protein, putative 0.003 0.0239 0.0974
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0006
Schistosoma mansoni myosin xvIII 0.0028 0.0224 0.0712
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0189 0.0768
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Onchocerca volvulus Neuropeptide F receptor homolog 0.0028 0.0224 0.0909
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.02 0.06
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.1077 0.8919
Echinococcus granulosus Smad4 0.0016 0.0093 0.0093
Onchocerca volvulus 0.003 0.0239 0.0974
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.043 0.0456
Echinococcus granulosus synaptic vesicle 2 protein 0.003 0.0239 0.0239
Plasmodium vivax glutathione reductase, putative 0.0048 0.043 0.0456
Loa Loa (eye worm) hypothetical protein 0.003 0.0244 0.073
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Leishmania major protein kinase, putative 0.0029 0.0232 0.3273
Echinococcus granulosus somatostatin receptor 0.0028 0.0224 0.0224
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.0708 1
Brugia malayi MH2 domain containing protein 0.0016 0.0093 0.028
Plasmodium vivax CDK-related protein kinase 6, putative 0.0898 0.9426 1
Loa Loa (eye worm) RecQ helicase 0.0022 0.0153 0.0457
Schistosoma mansoni histidyl-tRNA synthetase 0.0007 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0226 0.0676
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0051 0.0711
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0078 0.0234
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Onchocerca volvulus 0.003 0.0239 0.0974
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0028 0.0224 0.067
Schistosoma mansoni smad 0.0016 0.0093 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0108 0.0108
Trichomonas vaginalis glucose transporter, putative 0.003 0.0239 0.0974
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0029 0.0232 0.3273
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0212 0.2163 0.2163
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0096 0.0938 0.0938
Echinococcus granulosus 7tm_1 domain containing protein 0.0028 0.0224 0.0224
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0189 0.0768
Loa Loa (eye worm) melatonin receptor type 1A 0.0028 0.0224 0.067
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0169 0.0686
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0007 0.0002 0.0006
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0007 0.0002 0.0007
Schistosoma mansoni sugar transporter 0.003 0.0239 0.0763
Brugia malayi bHLH-PAS transcription factor 0.0071 0.0677 0.203
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0022 0.0162 0.2386
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0007 0.0002 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.01 0.1406
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0029 0.0232 0.3273
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0619 0.8747
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0065 0.061 0.8623
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0108 0.0108
Leishmania major GTP-binding protein, putative 0.0021 0.0146 0.2062
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.01 0.0106
Onchocerca volvulus 0.003 0.0239 0.0974
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0007 0.0002 0.0007
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0619 0.2519
Trypanosoma brucei glucose transporter, putative 0.0066 0.0619 0.8747
Brugia malayi nuclear receptor NHR-88 0.0007 0.0002 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0007 0.0002 0.0006
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0619 0.2519
Echinococcus granulosus ecdysone induced protein 78C 0.0007 0.0002 0.0002
Loa Loa (eye worm) inositol-1 0.0036 0.0304 0.091
Echinococcus multilocularis sex peptide receptor 0.0028 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0036 0.0504
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.01 0.0405
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0212 0.2163 0.2163
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0153 0.0153
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.043 0.043
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0619 0.2519
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0146 0.2062
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0012 0.0051 0.1657
Trypanosoma cruzi hexose transporter 0.0066 0.0619 0.8747
Echinococcus granulosus G protein coupled receptor 139 0.0028 0.0224 0.0224
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0224 0.067
Onchocerca volvulus 0.003 0.0239 0.0974
Onchocerca volvulus 0.0026 0.0201 0.082
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0028 0.0224 0.0712
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0011 0.0036 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0224 0.0712
Loa Loa (eye worm) hypothetical protein 0.0009 0.0016 0.0049
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0424 0.1352
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.003 0.0239 0.1875
Brugia malayi Death domain containing protein 0.0015 0.0078 0.0234
Loa Loa (eye worm) sugar transporter 0.003 0.0239 0.0717
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0007 0.0002 0.0002
Echinococcus granulosus peptide allatostatin:somatostatin 0.0028 0.0224 0.0224
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0012 0.0051 0.0151
Echinococcus multilocularis somatostatin receptor 0.0028 0.0224 0.0224
Onchocerca volvulus 0.003 0.0239 0.0974
Echinococcus multilocularis serotonin receptor 0.0028 0.0224 0.0224
Echinococcus multilocularis solute carrier family 22 0.003 0.0239 0.0239
Echinococcus granulosus allatostatin A receptor 0.0028 0.0224 0.0224
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0244 0.0389
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0063 0.0596 0.0596
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.003 0.0239 0.3531
Brugia malayi hypoxia-induced factor 1 0.0298 0.3073 0.9208
Toxoplasma gondii transporter, major facilitator family protein 0.003 0.0239 0.0383
Brugia malayi Calcitonin receptor-like protein seb-1 0.0303 0.3127 0.9369
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0028 0.0224 0.0224
Loa Loa (eye worm) nuclear factor I 0.0009 0.0018 0.0054
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0304 0.0304
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0596 0.1901
Brugia malayi MH1 domain containing protein 0.0016 0.0093 0.028
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0006
Plasmodium falciparum importin beta, putative 0.0028 0.0226 0.0239
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0078 0.0249
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0224 0.0224
Echinococcus multilocularis Ankyrin 0.0015 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Mycobacterium tuberculosis Conserved hypothetical protein 0.0011 0.0036 0.0164
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0619 0.8747
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.1206 1
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0009 0.0024 0.034
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Echinococcus granulosus hypothetical protein 0.0028 0.0224 0.0224
Echinococcus multilocularis solute carrier family 22 0.003 0.0239 0.0239
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0224 0.0224
Echinococcus granulosus geminin 0.0167 0.1693 0.1693
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0007 0.0002 0.0007
Onchocerca volvulus 0.003 0.0239 0.0974
Onchocerca volvulus Putative transporter 0.003 0.0239 0.0974
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0073 0.0218
Onchocerca volvulus 0.003 0.0239 0.0974
Brugia malayi Dopamine receptor protein 2 0.0028 0.0224 0.067
Schistosoma mansoni RAR-like nuclear receptor 0.0007 0.0002 0.0007
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0047 0.0424 0.1727
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.2392 0.2392
Schistosoma mansoni inositol monophosphatase 0.0036 0.0304 0.0968
Loa Loa (eye worm) hypothetical protein 0.032 0.3315 0.9934
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.01 0.0106
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.01 0.1469
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0058 0.0058
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0028 0.0224 0.0712
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0342 0.3542 0.5667
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0303 0.3127 0.9369
Schistosoma mansoni glucose transport protein 0.0212 0.2163 0.6896
Leishmania major importin beta-1 subunit, putative 0.0023 0.0169 0.238
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0108 0.0344
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0212 0.2163 0.2163
Echinococcus multilocularis ecdysone induced protein 78C 0.0007 0.0002 0.0002
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0224 0.0224
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.01 0.1406
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Plasmodium falciparum thioredoxin reductase 0.0048 0.043 0.0456
Leishmania major glucose transporter, lmgt3 0.0066 0.0619 0.8747
Onchocerca volvulus 0.0028 0.0224 0.0909
Leishmania major glucose transporter/membrane transporter D2, putative 0.0066 0.0619 0.8747
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0096 0.0938 0.0938
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.003 0.0239 0.0763
Onchocerca volvulus 0.003 0.0239 0.0974
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0224 0.0224
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0007 0.0002 0.0006
Brugia malayi Protein kinase domain containing protein 0.0019 0.0121 0.0363
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0007 0.0002 0.0002
Brugia malayi hypothetical protein 0.0028 0.0224 0.067
Loa Loa (eye worm) TYRA-2 protein 0.0028 0.0224 0.067
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0007 0.0002 0.0006
Onchocerca volvulus 0.0028 0.0224 0.0909
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0007 0.0002 0.0002
Leishmania major protein kinase, putative 0.0029 0.0232 0.3273
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Trypanosoma brucei glucose transporter, putative 0.0066 0.0619 0.8747
Echinococcus multilocularis GPCR, family 2 0.0096 0.0938 0.0938
Loa Loa (eye worm) hypothetical protein 0.0052 0.047 0.1409
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0125 0.0132
Toxoplasma gondii sugar transporter ST3 0.003 0.0239 0.0383
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Schistosoma mansoni single-minded 0.0096 0.0942 0.3002
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0146 0.0233
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Schistosoma mansoni smad1 5 8 and 0.0016 0.0093 0.0297
Schistosoma mansoni nuclear hormone receptor 0.0007 0.0002 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0073 0.0218
Onchocerca volvulus 0.003 0.0239 0.0974
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0146 0.2237
Giardia lamblia Threonyl-tRNA synthetase 0.0012 0.0051 0.059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0007 0.0002 0.0006
Mycobacterium ulcerans hypothetical protein 0.0011 0.0036 0.0526
Echinococcus granulosus importin subunit beta 1 0.0028 0.0226 0.0226
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0224 0.0712
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0304 0.4291
Mycobacterium ulcerans sugar transporter 0.003 0.0239 0.3531
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0108 0.0114
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0224 0.0224
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.01 0.3278
Plasmodium falciparum proline--tRNA ligase 0.0074 0.0708 0.075
Echinococcus granulosus solute carrier family 22 0.003 0.0239 0.0239
Echinococcus granulosus solute carrier family 22 0.003 0.0239 0.0239
Treponema pallidum threonyl-tRNA synthetase 0.0012 0.0051 0.3113
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0047 0.0424 0.3319
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0028 0.0224 0.0909
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.004 0.0349 0.2796
Loa Loa (eye worm) hypothetical protein 0.0012 0.0053 0.0159
Loa Loa (eye worm) hypothetical protein 0.0207 0.2114 0.6333
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0189 0.2668
Brugia malayi MH1 domain containing protein 0.0009 0.0018 0.0054
Brugia malayi photoreceptor-specific nuclear receptor 0.0007 0.0002 0.0006
Schistosoma mansoni biogenic amine receptor 0.0028 0.0224 0.0712
Brugia malayi steroid hormone receptor 0.0007 0.0002 0.0006
Echinococcus multilocularis glycyl tRNA synthetase 0.0012 0.0051 0.0051
Leishmania major hypothetical protein, conserved 0.003 0.0239 0.3381
Schistosoma mansoni survival motor neuron protein 0.0048 0.0428 0.1364
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0189 0.0189
Mycobacterium ulcerans arylsulfatase, AslA 0.0009 0.0016 0.0238
Schistosoma mansoni smad1 5 8 and 0.0016 0.0093 0.0297
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0108 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0012 0.0051 0.0825
Giardia lamblia Glycyl-tRNA synthetase 0.0012 0.0051 0.059
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0244 0.0777
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.01 0.0159
Onchocerca volvulus 0.003 0.0239 0.0974
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Brugia malayi RNA, U transporter 1 0.0081 0.078 0.2338
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0239 0.0717
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.01 0.1406
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Schistosoma mansoni glucose transport protein 0.0212 0.2163 0.6896
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0303 0.3127 0.9369
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0145
Trichomonas vaginalis myo-inositol transporter, putative 0.003 0.0239 0.0974
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0224 0.0224
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0224 0.0224
Schistosoma mansoni glucose transport protein 0.0212 0.2163 0.6896
Echinococcus granulosus tachykinin peptides receptor 99D 0.0028 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0026 0.0201 0.0603
Brugia malayi Inositol-1 0.0036 0.0304 0.091
Echinococcus multilocularis neuropeptide receptor A26 0.0952 1 1
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0224 0.0224
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0224 0.0224
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0174 0.0174
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.01 0.0701
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0063 0.0596 0.4789
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0153 0.0621
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0224 0.0224
Schistosoma mansoni amine GPCR 0.0028 0.0224 0.0712
Echinococcus granulosus alpha 1A adrenergic receptor 0.0028 0.0224 0.0224
Schistosoma mansoni protein kinase 0.0065 0.061 0.1945
Trypanosoma brucei glucose transporter, putative 0.0066 0.0619 0.8747
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0093 0.0297
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0146 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0145
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0065 0.0611 0.0976
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0108 0.0172
Echinococcus multilocularis Sugar transporter ERD6 protein 0.003 0.0239 0.0239
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.01 0.1406
Onchocerca volvulus 0.0028 0.0224 0.0909
Loa Loa (eye worm) transcription factor SMAD2 0.0234 0.2401 0.7195
Schistosoma mansoni Smad4 0.0016 0.0093 0.0297
Trichomonas vaginalis set domain proteins, putative 0.0239 0.2456 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Schistosoma mansoni protein kinase 0.0065 0.061 0.1945
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0224 0.0224
Echinococcus granulosus calcium dependent protein kinase 0.0061 0.0568 0.0568
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0046 0.0653
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0712 0.0712
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0239 0.0974
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.1206 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0304 0.4481
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.061 0.061
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0304 0.1236
Echinococcus multilocularis snurportin 1 0.0304 0.3137 0.3137
Schistosoma mansoni hypothetical protein 0.0096 0.0938 0.2989
Onchocerca volvulus 0.003 0.0239 0.0974
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0078 0.0078
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0244 0.0244
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0108 0.0114
Schistosoma mansoni adenoreceptor 0.0028 0.0224 0.0712
Leishmania major trypanothione reductase 0.0048 0.043 0.6076
Schistosoma mansoni importin beta-1 0.0028 0.0226 0.0719
Echinococcus multilocularis transfer RNA-Lys 0.0071 0.0677 0.0677
Brugia malayi hypothetical protein 0.0028 0.0224 0.067
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.01 0.0299
Schistosoma mansoni sugar transporter 0.003 0.0239 0.0763
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.01 0.0318
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0226 0.0226
Schistosoma mansoni amine GPCR 0.0028 0.0224 0.0712
Brugia malayi putative neuropeptide receptor 0.0028 0.0224 0.067
Echinococcus granulosus Sugar transporter ERD6 protein 0.003 0.0239 0.0239
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0424 0.1352
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0174 0.0174
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0019 0.0056
Echinococcus multilocularis neuropeptide FF receptor 2 0.0028 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0028 0.0224 0.0224
Brugia malayi hypothetical protein 0.003 0.0239 0.0717
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0063 0.0596 0.9772
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0224 0.0712
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0012 0.0051 0.1657
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0189 0.2668
Brugia malayi Sulfatase family protein 0.0009 0.0016 0.0049
Brugia malayi Serotonin receptor 0.0028 0.0224 0.067
Echinococcus granulosus sodium channel protein 0.004 0.0344 0.0344
Schistosoma mansoni hypothetical protein 0.0207 0.2114 0.6737
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0108 0.1521
Brugia malayi hypothetical protein 0.0009 0.0016 0.0049
Brugia malayi follicle stimulating hormone receptor 0.025 0.2575 0.7716
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0019 0.0056
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0028 0.0224 0.0224
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0012 0.0051 0.0051
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0212 0.2163 0.2163
Schistosoma mansoni growth hormone secretagogue receptor 0.0028 0.0224 0.0712
Chlamydia trachomatis lysine--tRNA ligase 0.0047 0.0424 1
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0065 0.061 0.1828
Loa Loa (eye worm) hypothetical protein 0.0065 0.061 0.1828
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0239 0.0974
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0619 0.8747
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0108 0.1521
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.1077 0.8919
Schistosoma mansoni hypothetical protein 0.0212 0.2163 0.6896
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Plasmodium falciparum hexose transporter 0.0212 0.2163 0.2295
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Echinococcus granulosus sex peptide receptor 0.0028 0.0224 0.0224
Trypanosoma brucei glucose transporter, putative 0.0066 0.0619 0.8747
Chlamydia trachomatis threonine--tRNA ligase 0.0012 0.0051 0.1186
Schistosoma mansoni opsin-like receptor 0.0028 0.0224 0.0712
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.01 0.0106
Brugia malayi hypothetical protein 0.0233 0.2392 0.7169
Brugia malayi Uncoordinated protein 44 0.0015 0.0078 0.0234
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0226 0.036
Leishmania major glucose transporter, lmgt1 0.0066 0.0619 0.8747
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0244 0.0244
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0074 0.0708 1
Onchocerca volvulus 0.0025 0.0189 0.0769
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0028 0.0224 0.0224
Echinococcus granulosus lamin dm0 0.0026 0.0201 0.0201
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0108 0.0172
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Echinococcus granulosus GPCR family 2 0.0096 0.0938 0.0938
Mycobacterium ulcerans arylsulfatase AtsB 0.0009 0.0016 0.0238
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.2392 0.2392
Loa Loa (eye worm) hypothetical protein 0.0012 0.0053 0.0159
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0006
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.004 0.0344 0.0344
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0028 0.0224 0.067
Loa Loa (eye worm) hypothetical protein 0.0063 0.0596 0.1787
Onchocerca volvulus 0.0028 0.0224 0.0909
Echinococcus multilocularis allatostatin A receptor 0.0028 0.0224 0.0224
Giardia lamblia Sugar-proton symporter 0.003 0.0239 0.3846
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0007 0.0002 0.0008
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0007 0.0002 0.0002
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.061 0.061
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Echinococcus granulosus death domain containing protein 0.0015 0.0078 0.0078
Trypanosoma brucei sugar transporter, putative 0.003 0.0239 0.3381
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0224 0.0712
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0212 0.2163 0.2163
Echinococcus multilocularis g-protein coupled receptor 0.0028 0.0224 0.0224
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0224 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0304 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0078 0.0234
Plasmodium falciparum lysine--tRNA ligase 0.0047 0.0424 0.045
Echinococcus granulosus g-protein coupled receptor 0.0028 0.0224 0.0224
Mycobacterium tuberculosis Probable reductase 0.0109 0.1077 0.8919
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Brugia malayi hypothetical protein 0.0028 0.0224 0.067
Echinococcus granulosus g protein coupled receptor 0.0028 0.0224 0.0224
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.1077 0.8919
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0424 0.6262
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0619 0.2519
Schistosoma mansoni neuropeptide receptor 0.0028 0.0224 0.0712
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Echinococcus granulosus g protein coupled receptor 0.0028 0.0224 0.0224
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0108 0.0108
Plasmodium falciparum calcium-dependent protein kinase 1 0.0065 0.0611 0.0647
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0028 0.0224 0.067
Brugia malayi hypothetical protein 0.0123 0.1226 0.3672
Echinococcus granulosus glycyl tRNA synthetase 0.0012 0.0051 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0007 0.0002 0.0006
Brugia malayi isocitrate dehydrogenase 0.0017 0.0108 0.0323
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0212 0.2163 0.2163
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0224 0.0712
Plasmodium falciparum mitogen-activated protein kinase 2 0.0342 0.3542 0.3758
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0169 0.0686
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0189 0.0768
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0264 0.2082
Toxoplasma gondii facilitative glucose transporter GT1 0.0212 0.2163 0.3461
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.003 0.0239 0.3531
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0093 0.0093
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.061 0.061
Leishmania major hypothetical protein, conserved 0.0011 0.0036 0.0504
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0189 0.0768
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0007 0.0002 0.0002
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Onchocerca volvulus 0.0028 0.0224 0.0909
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0007 0.0002 0.0006
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0063 0.0596 0.1787
Schistosoma mansoni amine GPCR 0.0028 0.0224 0.0712
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0006
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0224 0.0224
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0169 0.0686
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0047 0.0424 0.5996
Trichomonas vaginalis ran, putative 0.0021 0.0146 0.0594
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0189 0.0768
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0007 0.0002 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0244 0.0777
Loa Loa (eye worm) hypothetical protein 0.0096 0.0938 0.281
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Echinococcus multilocularis orexin receptor type 2 0.0028 0.0224 0.0224
Leishmania major lysyl-tRNA synthetase, putative 0.0047 0.0424 0.5996
Echinococcus multilocularis serotonin receptor 0.0028 0.0224 0.0224
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.061 0.061
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0028 0.0224 0.0224
Brugia malayi Importin beta-1 subunit 0.0028 0.0226 0.0676
Plasmodium falciparum thioredoxin reductase 0.0017 0.01 0.0106
Schistosoma mansoni hypothetical protein 0.0015 0.0078 0.0249
Brugia malayi Nuclear hormone receptor-like 1 0.0007 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0238
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Onchocerca volvulus 0.0028 0.0224 0.0909
Schistosoma mansoni hypothetical protein 0.0028 0.0224 0.0712
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.01 0.0405
Brugia malayi Pre-SET motif family protein 0.003 0.0244 0.073
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0146 0.0438
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0007 0 0.0001
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0019 0.003
Onchocerca volvulus 0.0028 0.0224 0.0909
Echinococcus granulosus orexin receptor type 2 0.0028 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0224 0.0712
Echinococcus granulosus neuropeptide receptor A26 0.0952 1 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.01 0.1406
Onchocerca volvulus 0.003 0.0239 0.0974
Loa Loa (eye worm) hypothetical protein 0.0323 0.3337 1
Brugia malayi Thioredoxin reductase 0.0048 0.043 0.1288
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0007 0.0002 0.0006
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0304 0.4296
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.003 0.0239 0.0254
Schistosoma mansoni amine GPCR 0.0028 0.0224 0.0712
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0239 0.0717
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0304 0.4291
Mycobacterium ulcerans hydrolase 0.0009 0.0016 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0239 0.0974
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0012 0.0051 0.0151
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0036 0.0504
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0224 0.0712
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.01 0.0159
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Brugia malayi nuclear hormone receptor 0.0007 0.0002 0.0006
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0619 0.8747
Brugia malayi hypothetical protein 0.0028 0.0224 0.067
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0201 0.0603
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0007 0.0002 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0007 0.0002 0.0006
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.061 0.061
Mycobacterium ulcerans integral membrane transport protein 0.003 0.0239 0.3531
Entamoeba histolytica protein kinase, putative 0.0065 0.061 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Loa Loa (eye worm) hypothetical protein 0.0233 0.2392 0.7169
Leishmania major myo-inositol/proton symporter (MIT) 0.003 0.0239 0.3381
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0063 0.0596 0.1787
Schistosoma mansoni opsin-like receptor 0.0028 0.0224 0.0712
Echinococcus multilocularis solute carrier family 22 0.003 0.0239 0.0239
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.043 0.1288
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Brugia malayi hypothetical protein 0.0028 0.0224 0.067
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0201 0.0603
Onchocerca volvulus 0.0028 0.0224 0.0909
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0019 0.0056
Schistosoma mansoni hypothetical protein 0.0028 0.0224 0.0712
Loa Loa (eye worm) hypothetical protein 0.0009 0.0016 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Onchocerca volvulus 0.0026 0.0201 0.082
Schistosoma mansoni aryl hydrocarbon receptor 0.0096 0.0942 0.3002
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0108 0.1521
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0224 0.0224
Echinococcus multilocularis solute carrier family 22 0.003 0.0239 0.0239
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.01 0.1438
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0201 0.0603
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0105 0.0334
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0224 0.0712
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0619 0.2519
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Echinococcus granulosus fmrfamide receptor 0.0028 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Schistosoma mansoni sugar transporter 0.003 0.0239 0.0763
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0244 0.0777
Leishmania major hypothetical protein, conserved 0.0052 0.048 0.6782
Trichomonas vaginalis CAMK family protein kinase 0.0065 0.061 0.2483
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0153 0.0621
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0342 0.3542 0.3758
Schistosoma mansoni amine GPCR 0.0028 0.0224 0.0712
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Echinococcus multilocularis lamin 0.0026 0.0201 0.0201
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0224 0.0224
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0028 0.0224 0.067
Schistosoma mansoni opsin-like receptor 0.0028 0.0224 0.0712
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0036 0.0504
Leishmania major calcium channel protein, putative,ion transporter, putative 0.004 0.0344 0.4861
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0146 0.2062
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0145
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0065 0.0611 0.0647
Giardia lamblia Lysyl-tRNA synthetase 0.0047 0.0424 0.7035
Plasmodium vivax calcium-dependent protein kinase, putative 0.0065 0.0611 0.0647
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.0051 0.0743
Brugia malayi Serotonin receptor 0.0028 0.0224 0.067
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.048 0.6782
Brugia malayi G-protein coupled receptor 0.0028 0.0224 0.067
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Plasmodium falciparum threonine--tRNA ligase 0.0012 0.0051 0.0053
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.0708 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0244 0.0244
Schistosoma mansoni histidyl-tRNA synthetase 0.0007 0 0.0001
Schistosoma mansoni histamine h1 receptor 0.0028 0.0224 0.0712
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0189 0.0768
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0619 0.2519
Echinococcus granulosus single minded 2 0.0071 0.0677 0.0677
Brugia malayi G protein-coupled receptor F59B2.13 0.0028 0.0224 0.067
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Brugia malayi hypothetical protein 0.0028 0.0224 0.067
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0012 0.0051 0.0825
Schistosoma mansoni neuropeptide receptor 0.0028 0.0224 0.0712
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0304 0.0304
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.01 0.1406
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0224 0.067
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Toxoplasma gondii sugar transporter ST2 0.003 0.0239 0.0383
Echinococcus granulosus solute carrier family 22 0.003 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0006
Loa Loa (eye worm) glutathione reductase 0.0048 0.043 0.1288
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0232 0.0232
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0028 0.0224 0.0712
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.2149 0.6439
Leishmania major glucose transporter, lmgt2 0.0066 0.0619 0.8747
Echinococcus granulosus solute carrier family 22 0.003 0.0239 0.0239
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.048 0.6782
Onchocerca volvulus Bile acid receptor homolog 0.0007 0.0002 0.0008
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0065 0.0611 0.0647
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0007 0.0002 0.0002
Schistosoma mansoni alpha-1 adrenergic receptor 0.0028 0.0224 0.0712
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.01 0.1406
Trypanosoma brucei trypanothione reductase 0.0048 0.043 0.6076
Schistosoma mansoni hypothetical protein 0.0167 0.1693 0.5397
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.043 0.6076
Brugia malayi Dopamine receptor 0.0028 0.0224 0.067
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0239 0.0717
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Schistosoma mansoni sugar transporter 0.003 0.0239 0.0763
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0028 0.0224 0.0224
Trypanosoma cruzi hexose transporter, putative 0.003 0.0239 0.3381
Echinococcus granulosus serotonin receptor 0.0028 0.0224 0.0224
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0108 0.0108
Schistosoma mansoni hypothetical protein 0.0096 0.0938 0.2989
Plasmodium vivax proline--tRNA ligase, putative 0.0074 0.0708 0.075
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0093 0.0093
Onchocerca volvulus 0.0071 0.0677 0.2757
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0226 0.3185
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0096 0.0938 0.0938
Onchocerca volvulus 0.0048 0.0428 0.1741
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0012 0.0051 0.0288
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0108 0.1521
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0046 0.0188
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0028 0.0224 0.0712
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0169 0.238
Trypanosoma brucei glucose transporter 1E 0.0066 0.0619 0.8747
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0224 0.0224
Trypanosoma brucei glucose transporter, putative 0.0066 0.0619 0.8747
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0224 0.0224
Echinococcus multilocularis synaptic vesicle 2 protein 0.003 0.0239 0.0239
Brugia malayi intermediate filament protein 0.0026 0.0201 0.0603
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0019 0.003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0007 0.0002 0.0006
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0036 0.0504
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0712 0.0712
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0078 0.0318
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0007 0.0002 0.0002
Loa Loa (eye worm) steroid hormone receptor 0.0007 0.0002 0.0006
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0077 0.0123
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0239 0.0717
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0029 0.0232 0.3273
Schistosoma mansoni protein kinase 0.0065 0.061 0.1945
Echinococcus granulosus intermediate filament protein 0.0026 0.0201 0.0201
Plasmodium vivax sugar transporter, putative 0.003 0.0239 0.0254
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0007 0.0002 0.0007
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0424 0.6262
Schistosoma mansoni hypothetical protein 0.0304 0.3137 1
Echinococcus multilocularis musashi 0.0026 0.0201 0.0201
Echinococcus granulosus dro:myosuppressin receptor 0.0028 0.0224 0.0224
Mycobacterium ulcerans arylsulfatase AtsD 0.0009 0.0016 0.0238
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0074 0.0708 1
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0009 0.0016 0.0066
Schistosoma mansoni netrin receptor unc5 0.0015 0.0078 0.0249
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.0051 0.0743
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0304 0.4976
Leishmania major protein kinase, putative 0.0065 0.061 0.8623
Echinococcus granulosus snurportin 1 0.0304 0.3137 0.3137
Echinococcus multilocularis calcium dependent protein kinase 0.0061 0.0568 0.0568
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.003 0.0239 0.1875
Echinococcus multilocularis G-protein coupled receptor, putative 0.0028 0.0224 0.0224
Schistosoma mansoni hypothetical protein 0.0028 0.0224 0.0712
Brugia malayi hypothetical protein 0.003 0.0239 0.0717
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0717
Loa Loa (eye worm) hypothetical protein 0.0028 0.0224 0.067
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0224 0.0712
Onchocerca volvulus 0.003 0.0239 0.0974
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0146 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0066
Treponema pallidum NADH oxidase 0.0017 0.01 0.6156
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0007 0.0002 0.0002
Brugia malayi glutathione reductase 0.0048 0.043 0.1288
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.0051 0.0711
Brugia malayi RE15519p 0.0028 0.0224 0.067
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0224 0.0712
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Trichomonas vaginalis sugar transporter, putative 0.003 0.0239 0.0974
Giardia lamblia Hexose transporter 0.003 0.0239 0.3846
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.1206 1

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 9.285 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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