Detailed information for compound 1733736

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 591.622 | Formula: C31H25F4N5OS
  • H donors: 0 H acceptors: 3 LogP: 5.81 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: Fc1ccc(cc1)CSc1nc(=O)c2c(n1Cc1nncn1Cc1ccc(cc1)c1ccc(cc1)C(F)(F)F)CCC2
  • InChi: 1S/C31H25F4N5OS/c32-25-14-6-21(7-15-25)18-42-30-37-29(41)26-2-1-3-27(26)40(30)17-28-38-36-19-39(28)16-20-4-8-22(9-5-20)23-10-12-24(13-11-23)31(33,34)35/h4-15,19H,1-3,16-18H2
  • InChiKey: IHSZWMLAIBYINV-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis histone deacetylase 0.0383 0.1168 0.153
Echinococcus granulosus protein kinase 0.008 0.0125 0.0163
Brugia malayi Histone deacetylase family protein 0.0383 0.1168 0.153
Echinococcus multilocularis raf serine:threonine protein kinase 0.0057 0.0045 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0205 0.0554 0.0726
Leishmania major protein kinase A catalytic subunit isoform 1 0.01 0.0191 0.0924
Giardia lamblia Aurora kinase 0.0552 0.1751 1
Trichomonas vaginalis histone deacetylase, putative 0.0457 0.1425 0.8139
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0195 0.0519 0.2508
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0065 0.0072 0.0346
Schistosoma mansoni tyrosine kinase 0.1211 0.4023 0.527
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0062 0.006 0.0078
Loa Loa (eye worm) hypothetical protein 0.0058 0.0046 0.0061
Schistosoma mansoni protein kinase 0.0059 0.0051 0.0067
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0127 0.0286 0.0375
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0066 0.0075 0.0098
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0127 0.0286 0.0375
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.01 0.0191 0.0924
Echinococcus granulosus c src tyrosine kinase 0.0084 0.0137 0.018
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0457 0.1425 0.8139
Brugia malayi casein kinase I 0.0059 0.0051 0.0067
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0457 0.1425 0.8139
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0139 0.0326 0.1577
Loa Loa (eye worm) hypothetical protein 0.0058 0.0046 0.0061
Brugia malayi Protein kinase domain containing protein 0.031 0.0915 0.1199
Brugia malayi hypothetical protein 0.0059 0.0051 0.0067
Onchocerca volvulus 0.0914 0.3001 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0094 0.0172 0.0226
Echinococcus multilocularis histone deacetylase 3 0.0457 0.1425 0.1867
Trypanosoma brucei aurora B kinase 0.0552 0.1751 0.8467
Loa Loa (eye worm) hypothetical protein 0.0074 0.0102 0.0133
Trypanosoma cruzi casein kinase, putative 0.0059 0.0051 0.0246
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.011 0.0227 0.0298
Entamoeba histolytica casein kinase 1, putative 0.0059 0.0051 0.029
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.01 0.0191 0.025
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0147 0.0353 0.0463
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0065 0.0072 0.0346
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0112 0.0235 0.0308
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0644 0.2068 1
Schistosoma mansoni serine/threonine kinase 0.006 0.0053 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.0483 0.0633
Echinococcus multilocularis Immunoglobulin 0.0114 0.0241 0.0316
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0066 0.0075 0.0098
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0059 0.005 0.0066
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.2944 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.024 0.0314
Loa Loa (eye worm) TK/ALK protein kinase 0.0538 0.1703 0.2231
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0147 0.0353 0.1707
Brugia malayi Immunoglobulin I-set domain containing protein 0.0061 0.0058 0.0077
Echinococcus granulosus histone deacetylase 8 0.019 0.0502 0.0658
Schistosoma mansoni cell adhesion molecule 0.0058 0.0046 0.0061
Onchocerca volvulus 0.0066 0.0075 0.01
Brugia malayi Protein kinase domain containing protein 0.0149 0.0361 0.0473
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0079 0.012 0.0158
Trypanosoma cruzi casein kinase, putative 0.0059 0.0051 0.0246
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0074 0.0103 0.0134
Echinococcus multilocularis casein kinase I alpha 0.0059 0.0051 0.0067
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0095 0.0177 0.0231
Echinococcus granulosus activin receptor type 0.0418 0.1291 0.1691
Schistosoma mansoni neuroglian 0.0061 0.0058 0.0077
Loa Loa (eye worm) hypothetical protein 0.0058 0.0048 0.0062
Echinococcus granulosus cyclin dependent kinase 7 0.0097 0.0181 0.0237
Echinococcus multilocularis serine:threonine protein kinase N2 0.0046 0.0007 0.0009
Echinococcus granulosus mitogen activated protein kinase 11 0.0644 0.2068 0.2709
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0165 0.0418 0.2022
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0112 0.0233 0.0305
Loa Loa (eye worm) TK protein kinase 0.0094 0.0172 0.0226
Loa Loa (eye worm) hypothetical protein 0.0059 0.0051 0.0067
Plasmodium vivax histone deacetylase 1, putative 0.0457 0.1425 0.8111
Echinococcus granulosus serine:threonine protein kinase 0.0062 0.006 0.0078
Echinococcus granulosus c-Jun N-terminal kinases 0.0245 0.0694 0.0909
Trypanosoma cruzi histone deacetylase, putative 0.019 0.0502 0.2428
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0059 0.005 0.0287
Echinococcus multilocularis protein KINase family member (kin 25) 0.0104 0.0207 0.0271
Echinococcus granulosus histone deacetylase 1 0.0457 0.1425 0.1867
Trichomonas vaginalis AGC family protein kinase 0.0049 0.0018 0.0102
Echinococcus granulosus cyclin dependent kinase 1 0.0147 0.0353 0.0463
Loa Loa (eye worm) hypothetical protein 0.0118 0.0253 0.0332
Entamoeba histolytica protein kinase, putative 0.0071 0.0092 0.0523
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.031 0.0915 0.1199
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0058 0.0046 0.0061
Plasmodium falciparum histone deacetylase, putative 0.0383 0.1168 0.6669
Schistosoma mansoni protein kinase C mu 0.0096 0.0179 0.0234
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0166 0.0419 0.055
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.01 0.0191 0.025
Echinococcus granulosus tyrosine protein kinase Src42A 0.0112 0.0235 0.0308
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0046 0.0007 0.0009
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0177 0.0456 0.0598
Echinococcus granulosus protein kinase C gamma type 0.0046 0.0007 0.0009
Entamoeba histolytica histone deacetylase, putative 0.0457 0.1425 0.8139
Brugia malayi protein unc-22 0.0057 0.0045 0.006
Entamoeba histolytica protein kinase, putative 0.0115 0.0243 0.1389
Loa Loa (eye worm) hypothetical protein 0.0073 0.0099 0.013
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0114 0.024 0.1159
Schistosoma mansoni tyrosine kinase 0.0104 0.0207 0.0271
Echinococcus multilocularis protein kinase shaggy 0.0115 0.0243 0.0319
Echinococcus multilocularis tyrosine protein kinase Srms 0.0094 0.0172 0.0226
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0352 0.0461
Echinococcus multilocularis serine:threonine protein kinase 0.0062 0.006 0.0078
Brugia malayi Protein kinase domain containing protein 0.0147 0.0353 0.0463
Echinococcus granulosus tyrosine kinase 0.0094 0.0172 0.0226
Entamoeba histolytica PH domain containing protein kinase, putative 0.0103 0.0203 0.1157
Plasmodium falciparum glycogen synthase kinase 3 0.0115 0.0243 0.1389
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0059 0.005 0.0066
Leishmania major histone deacetylase, putative 0.0383 0.1168 0.5646
Brugia malayi serine/threonine-protein kinase plk-2 0.0114 0.024 0.0314
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.024 0.1159
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0456 0.0598
Loa Loa (eye worm) hypothetical protein 0.0172 0.044 0.0577
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0552 0.1751 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0112 0.0235 0.0308
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0115 0.0243 0.0319
Brugia malayi Stress-activated protein kinase jnk-1 0.0245 0.0694 0.0909
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0073 0.0099 0.013
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0052 0.0027 0.0035
Loa Loa (eye worm) hypothetical protein 0.014 0.0332 0.0435
Loa Loa (eye worm) hypothetical protein 0.0131 0.0299 0.0392
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0139 0.0326 0.1577
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0199 0.0535 0.0701
Schistosoma mansoni protein kinase 0.0166 0.0419 0.055
Onchocerca volvulus 0.0059 0.0051 0.0018
Echinococcus multilocularis mitogen activated protein kinase 11 0.0644 0.2068 0.2709
Plasmodium vivax histone deacetylase 2, putative 0.0383 0.1168 0.6618
Plasmodium vivax calcium-dependent protein kinase, putative 0.0059 0.005 0.0139
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0149 0.0361 0.0473
Onchocerca volvulus 0.0074 0.0102 0.019
Loa Loa (eye worm) hypothetical protein 0.0059 0.005 0.0066
Echinococcus granulosus calcium activated potassium channel 0.0052 0.0027 0.0035
Plasmodium falciparum NIMA related kinase 1 0.0122 0.0268 0.1531
Entamoeba histolytica protein kinase, putative 0.0046 0.0007 0.0037
Schistosoma mansoni cell adhesion molecule 0.0061 0.0058 0.0077
Echinococcus granulosus titin 0.0057 0.0045 0.006
Loa Loa (eye worm) hypothetical protein 0.0134 0.0309 0.0405
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0112 0.0235 0.0308
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0046 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0191 0.025
Trichomonas vaginalis AGC family protein kinase 0.0049 0.0018 0.0102
Echinococcus granulosus tyrosine protein kinase Srms 0.0066 0.0075 0.0098
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0215 0.0589 0.0771
Brugia malayi intracellular kinase 0.0115 0.0243 0.0319
Loa Loa (eye worm) hypothetical protein 0.0062 0.006 0.0078
Echinococcus granulosus casein kinase I alpha 0.0059 0.0051 0.0067
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0114 0.0241 0.0316
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0046 0.0061
Trichomonas vaginalis AGC family protein kinase 0.0049 0.0018 0.0102
Loa Loa (eye worm) hypothetical protein 0.0124 0.0276 0.0361
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0075 0.0098
Brugia malayi Immunoglobulin I-set domain containing protein 0.017 0.0432 0.0566
Loa Loa (eye worm) hypothetical protein 0.0062 0.006 0.0079
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0059 0.005 0.0139
Onchocerca volvulus 0.0059 0.0051 0.0019
Echinococcus granulosus casein kinase I alpha 0.0059 0.0051 0.0067
Brugia malayi C1-like domain containing protein 0.0096 0.0179 0.0234
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0059 0.005 0.0287
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.024 0.1369
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0137 0.0321 0.042
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0073 0.0099 0.013
Trichomonas vaginalis STE family protein kinase 0.0165 0.0418 0.2389
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0061 0.0058 0.0077
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.054 0.1709 0.976
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0245 0.0694 0.0909
Trichomonas vaginalis STE family protein kinase 0.0165 0.0418 0.2389
Brugia malayi Protein kinase domain containing protein 0.0066 0.0075 0.0098
Loa Loa (eye worm) hypothetical protein 0.0073 0.0099 0.013
Entamoeba histolytica protein kinase, putative 0.0195 0.0519 0.2962
Leishmania major histone deacetylase, putative 0.0457 0.1425 0.6891
Schistosoma mansoni tyrosine kinase 0.0084 0.0137 0.018
Brugia malayi protein-tyrosine kinase 0.0094 0.0172 0.0226
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0134 0.0309 0.0405
Loa Loa (eye worm) histone deacetylase 1 0.0457 0.1425 0.1867
Loa Loa (eye worm) AGC/AKT protein kinase 0.0049 0.0018 0.0023
Echinococcus granulosus neuroglian 0.0146 0.035 0.0458
Echinococcus multilocularis histone deacetylase 7 0.0383 0.1168 0.153
Schistosoma mansoni protein kinase 0.0092 0.0164 0.0214
Schistosoma mansoni tyrosine kinase 0.1211 0.4023 0.527
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0027 0.0152
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0114 0.024 0.0314
Echinococcus granulosus tyrosine protein kinase shark 0.0066 0.0075 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.0139 0.0326 0.0427
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0057 0.0075
Trypanosoma cruzi casein kinase, putative 0.0059 0.0051 0.0246
Schistosoma mansoni protein kinase 0.0552 0.1751 0.2294
Leishmania major protein kinase, putative 0.0059 0.005 0.0243
Loa Loa (eye worm) histone deacetylase 11 0.019 0.0502 0.0658
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0181 0.0237
Loa Loa (eye worm) TK/ROR protein kinase 0.0074 0.0103 0.0134
Entamoeba histolytica protein kinase, putative 0.0059 0.005 0.0287
Loa Loa (eye worm) hypothetical protein 0.0058 0.0046 0.0061
Echinococcus granulosus tyrosine protein kinase HCK 0.0071 0.0092 0.012
Echinococcus granulosus casein kinase I delta 0.0059 0.0051 0.0067
Leishmania major protein kinase, putative 0.0065 0.0072 0.0346
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0161 0.0212
Onchocerca volvulus Tyrosine kinase homolog 0.0831 0.2715 0.903
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0139 0.0326 0.0427
Brugia malayi Protein kinase domain containing protein 0.0066 0.0075 0.0098
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0018 0.0102
Schistosoma mansoni titin 0.0058 0.0046 0.0061
Brugia malayi p70 ribosomal S6 kinase beta 0.0046 0.0007 0.0009
Schistosoma mansoni histone deacetylase 1 2 3 0.019 0.0502 0.0658
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0112 0.0235 0.0308
Echinococcus multilocularis histone deacetylase 8 0.019 0.0502 0.0658
Brugia malayi Protein kinase domain containing protein 0.0081 0.0129 0.0168
Brugia malayi Protein kinase domain containing protein 0.0899 0.2947 0.3861
Echinococcus granulosus tyrosine kinase 0.0066 0.0075 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0353 0.0463
Loa Loa (eye worm) AGC/PKA protein kinase 0.01 0.0191 0.025
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0184 0.0483 0.0632
Loa Loa (eye worm) AUR protein kinase 0.0552 0.1751 0.2294
Trypanosoma cruzi casein kinase, putative 0.0059 0.0051 0.0246
Brugia malayi Protein kinase domain containing protein 0.085 0.2778 0.3639
Trypanosoma cruzi histone deacetylase, putative 0.0383 0.1168 0.5646
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0147 0.0353 0.0463
Echinococcus granulosus cyclin dependent kinase 9 0.0074 0.0101 0.0133
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0644 0.2068 1
Leishmania major protein kinase A catalytic subunit isoform 2 0.01 0.0191 0.0924
Schistosoma mansoni tyrosine kinase 0.0138 0.0324 0.0424
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0033 0.0187
Loa Loa (eye worm) hypothetical protein 0.0069 0.0086 0.0113
Giardia lamblia Kinase, CMGC CDK 0.0147 0.0353 0.1895
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0107 0.0217 0.0284
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0051 0.0067
Brugia malayi Histone deacetylase 1 0.0457 0.1425 0.1867
Echinococcus granulosus epidermal growth factor receptor 0.2258 0.7634 1
Echinococcus multilocularis neuroglian 0.0146 0.035 0.0458
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0079 0.012 0.0157
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0122 0.0268 0.1401
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0165 0.0418 0.2022
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0046 0.0061
Trichomonas vaginalis histone deacetylase, putative 0.0457 0.1425 0.8139
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.01 0.0191 0.0924
Loa Loa (eye worm) TK/ABL protein kinase 0.067 0.216 0.2829
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0027 0.0035
Entamoeba histolytica tyrosin kinase, putative 0.0049 0.0018 0.0102
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0243 0.1389
Echinococcus granulosus cyclin dependent kinase 0.0147 0.0353 0.0463
Entamoeba histolytica cell division protein kinase 2, putative 0.0147 0.0353 0.2017
Schistosoma mansoni ephrin receptor 0.0046 0.0006 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0147 0.0353 0.2017
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0353 0.0463
Loa Loa (eye worm) AUR protein kinase 0.0552 0.1751 0.2294
Schistosoma mansoni protein kinase 0.0065 0.0072 0.0094
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0061 0.0058 0.0077
Echinococcus multilocularis cyclin dependent kinase 1 0.0147 0.0353 0.0463
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0177 0.0456 0.139
Schistosoma mansoni septate junction protein 0.0058 0.0046 0.0061
Echinococcus granulosus protein kinase c epsilon type 0.0061 0.0057 0.0075
Loa Loa (eye worm) hypothetical protein 0.0058 0.0046 0.0061
Toxoplasma gondii aurora kinase 0.0552 0.1751 1
Schistosoma mansoni atypical protein kinase C 0.0061 0.0057 0.0075
Loa Loa (eye worm) hypothetical protein 0.0077 0.0113 0.0148
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0074 0.0103 0.0134
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0075 0.0098
Plasmodium vivax histone deacetylase, putative 0.019 0.0502 0.2759
Trichomonas vaginalis CK1 family protein kinase 0.0059 0.0051 0.029
Echinococcus multilocularis protein kinase c iota type 0.0061 0.0057 0.0075
Trypanosoma cruzi cdc2-related kinase 3 0.0147 0.0353 0.1707
Onchocerca volvulus 0.0073 0.0099 0.0182
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0165 0.0418 0.2022
Schistosoma mansoni tyrosine kinase 0.0084 0.0137 0.018
Brugia malayi Protein kinase domain containing protein 0.0046 0.0007 0.0009
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0139 0.0326 0.1577
Echinococcus multilocularis hemicentin 1 0.0058 0.0046 0.0061
Echinococcus multilocularis casein kinase I alpha 0.0059 0.0051 0.0067
Echinococcus multilocularis calcium activated potassium channel 0.0052 0.0027 0.0035
Trichomonas vaginalis STE family protein kinase 0.0122 0.0268 0.1531
Giardia lamblia Kinase, AGC AKT 0.0104 0.0205 0.1034
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0177 0.0456 0.0598
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0084 0.0137 0.018
Loa Loa (eye worm) hypothetical protein 0.0114 0.0241 0.0316
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0552 0.1751 0.2294
Trypanosoma cruzi cdc2-related kinase 1 0.0147 0.0353 0.1707
Trypanosoma brucei cdc2-related kinase 1 0.0147 0.0353 0.1707
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0177 0.0456 0.0598
Plasmodium falciparum protein kinase 5 0.0147 0.0353 0.2017
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0184 0.0483 0.0632
Schistosoma mansoni nephrin 0.0149 0.0362 0.0474
Echinococcus multilocularis cyclin dependent kinase 5 0.0147 0.0353 0.0463
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0134 0.0309 0.0405
Echinococcus granulosus fibroblast growth factor receptor 4 0.0138 0.0324 0.0424
Trypanosoma brucei histone deacetylase 3 0.0383 0.1168 0.5646
Brugia malayi SH2 domain containing protein 0.0066 0.0075 0.0098
Entamoeba histolytica protein kinase, putative 0.0046 0.0007 0.0037
Echinococcus multilocularis aurora kinase A 0.0552 0.1751 0.2294
Echinococcus multilocularis serine:threonine protein kinase 0.0062 0.006 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0181 0.0237
Schistosoma mansoni tyrosine kinase 0.0647 0.2079 0.2723
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0899 0.2947 0.3861
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0139 0.0326 0.1577
Entamoeba histolytica casein kinase, putative 0.0059 0.0051 0.029
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0853 0.279 0.3655
Echinococcus granulosus Immunoglobulin 0.0114 0.0241 0.0316
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0215 0.0589 0.0771
Brugia malayi Temporarily assigned gene name protein 59 0.0073 0.0099 0.013
Brugia malayi Protein kinase domain containing protein 0.0066 0.0075 0.0098
Echinococcus granulosus peroxidasin 0.0058 0.0048 0.0062
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0058 0.0046 0.0061
Schistosoma mansoni kinase 0.0066 0.0075 0.0098
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.024 0.1369
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.2944 1 0.5
Loa Loa (eye worm) hypothetical protein 0.016 0.04 0.0523
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0166 0.0419 0.055
Brugia malayi Peroxidasin 0.0058 0.0048 0.0062
Brugia malayi serine/threonine kinase 12 0.0552 0.1751 0.2294
Echinococcus granulosus tyrosine protein kinase Src42A 0.0053 0.0031 0.0041
Onchocerca volvulus Histone deacetylase 10 homolog 0.019 0.0502 0.1545
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0057 0.0075
Echinococcus granulosus casein kinase i 0.0059 0.0051 0.0067
Plasmodium vivax protein kinase Crk2 0.0147 0.0353 0.1895
Loa Loa (eye worm) hypothetical protein 0.0058 0.0046 0.0061
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0644 0.2068 0.2709
Brugia malayi Hr1 repeat family protein 0.0046 0.0007 0.0009
Toxoplasma gondii histone deacetylase HDAC5 0.019 0.0502 0.2867
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0046 0.0006 0.0033
Entamoeba histolytica cell division protein kinase 2, putative 0.0154 0.0379 0.2167
Echinococcus multilocularis casein kinase I delta 0.0059 0.0051 0.0067
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0075 0.0098
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0046 0.0007 0.0009
Brugia malayi Protein kinase domain containing protein 0.0066 0.0075 0.0098
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0644 0.2068 1
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0092 0.0164 0.0214
Trichomonas vaginalis AGC family protein kinase 0.0049 0.0018 0.0102
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0096 0.0179 0.0234
Schistosoma mansoni hypothetical protein 0.0073 0.0099 0.013
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.01 0.0191 0.025
Toxoplasma gondii histone deacetylase HDAC1 0.0383 0.1168 0.6669
Trypanosoma cruzi cdc2-related kinase 3 0.0147 0.0353 0.1707
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0112 0.0235 0.0308
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0184 0.0483 0.0633
Echinococcus granulosus rho-associated protein kinase 1 0.0304 0.0896 0.1174
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0552 0.1751 1
Loa Loa (eye worm) AGC/NDR protein kinase 0.0046 0.0007 0.0009
Entamoeba histolytica protein kinase, putative 0.0046 0.0006 0.0033
Echinococcus granulosus activated cdc42 kinase 1 0.0203 0.0546 0.0715
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0059 0.005 0.0139
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0058 0.0046 0.0061
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0052 0.0067
Brugia malayi Protein kinase domain containing protein 0.0914 0.3001 0.3932
Schistosoma mansoni tyrosine kinase 0.0112 0.0235 0.0308
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0112 0.0235 0.0308
Trypanosoma brucei histone deacetylase 1 0.0457 0.1425 0.6891
Plasmodium falciparum serine/threonine protein kinase, putative 0.0552 0.1751 1
Plasmodium falciparum histone deacetylase 2 0.0383 0.1168 0.6669
Brugia malayi cyclin-dependent kinase 9 0.0066 0.0075 0.0098
Echinococcus granulosus cyclin dependent kinase 5 0.0147 0.0353 0.0463
Toxoplasma gondii histone deacetylase HDAC2 0.0457 0.1425 0.8139
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0245 0.0694 0.0909
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0073 0.0099 0.048
Loa Loa (eye worm) hypothetical protein 0.0118 0.0253 0.0332
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.031 0.0915 0.1199
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0073 0.0099 0.013
Echinococcus granulosus tyrosine protein kinase otk 0.0058 0.0046 0.0061
Brugia malayi Immunoglobulin I-set domain containing protein 0.0057 0.0045 0.006
Trichomonas vaginalis CK1 family protein kinase 0.0059 0.0051 0.029
Echinococcus granulosus titin 0.0057 0.0045 0.006
Echinococcus granulosus tyrosine protein kinase ABL1 0.067 0.216 0.2829
Brugia malayi serine/threonine-protein kinase 6 0.0552 0.1751 0.2294
Loa Loa (eye worm) AGC/PKA protein kinase 0.01 0.0191 0.025
Plasmodium falciparum protein serine/threonine kinase-1 0.0139 0.0326 0.1863
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0146 0.0352 0.0461
Giardia lamblia Histone deacetylase 0.0457 0.1425 0.8111
Loa Loa (eye worm) gastrulation defective protein 1 0.0126 0.0284 0.0371
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0115 0.0243 0.0319
Schistosoma mansoni protein kinase 0.008 0.0125 0.0163
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0191 0.025
Echinococcus multilocularis casein kinase i 0.0059 0.0051 0.0067
Brugia malayi histone deacetylase 11 0.019 0.0502 0.0658
Echinococcus granulosus serine:threonine protein kinase 0.0062 0.006 0.0078
Plasmodium vivax serine/threonine kinase-1, putative 0.0139 0.0326 0.1739
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0114 0.024 0.0314
Onchocerca volvulus 0.0066 0.0075 0.01
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0061 0.0058 0.0077
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0115 0.0243 0.1389
Loa Loa (eye worm) hypothetical protein 0.0468 0.1463 0.1916
Echinococcus granulosus activated cdc42 kinase 1 0.0203 0.0546 0.0715
Brugia malayi Protein kinase domain containing protein 0.0112 0.0233 0.0305
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.01 0.0191 0.0924
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0058 0.0046 0.0061
Trichomonas vaginalis AGC family protein kinase 0.0049 0.0018 0.0102
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0131 0.0299 0.0392
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0075 0.0098
Brugia malayi Furin-like cysteine rich region family protein 0.2258 0.7634 1
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0066 0.0075 0.0098
Giardia lamblia Kinase, CMGC CLK 0.0139 0.0326 0.1739
Schistosoma mansoni serine/threonine protein kinase 0.0304 0.0896 0.1174
Echinococcus granulosus dual specificity 0.0195 0.0519 0.0679
Brugia malayi hypothetical protein 0.0118 0.0253 0.0332
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0853 0.279 0.3655
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0146 0.0352 0.0461
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0057 0.0045 0.006
Plasmodium falciparum histone deacetylase 1 0.0457 0.1425 0.8139
Brugia malayi serine/threonine protein kinase 6 0.0552 0.1751 0.2294
Leishmania major protein kinase, putative 0.0139 0.0326 0.1577
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0059 0.005 0.0139
Loa Loa (eye worm) hypothetical protein 0.0066 0.0075 0.0098
Brugia malayi Immunoglobulin I-set domain containing protein 0.0061 0.0058 0.0077
Schistosoma mansoni tyrosine kinase 0.0196 0.0524 0.0686
Trypanosoma brucei rac serine-threonine kinase, putative 0.0049 0.0018 0.0087
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0057 0.0075
Brugia malayi Protein kinase domain containing protein 0.0139 0.0326 0.0427
Brugia malayi Protein kinase domain containing protein 0.0066 0.0075 0.0098
Echinococcus granulosus protein kinase c iota type 0.0061 0.0057 0.0075
Schistosoma mansoni tyrosine kinase 0.0058 0.0046 0.0061
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.01 0.0191 0.0924
Loa Loa (eye worm) hypothetical protein 0.0058 0.0046 0.0061
Brugia malayi Serine/threonine-protein kinase SULU 0.0205 0.0554 0.0726
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.0519 0.0679
Echinococcus granulosus histone deacetylase 6 0.0383 0.1168 0.153
Schistosoma mansoni tyrosine kinase 0.1211 0.4023 0.527
Brugia malayi serine/threonine-protein kinase PAK 7 0.0199 0.0535 0.0701
Echinococcus granulosus casein kinase I alpha 0.0059 0.0051 0.0067
Entamoeba histolytica serine/threonine protein kinase, putative 0.0114 0.024 0.1369
Giardia lamblia Kinase, CMGC GSK 0.0115 0.0243 0.1257
Brugia malayi Protein kinase domain containing protein 0.0052 0.0027 0.0035
Brugia malayi Fibronectin type III domain containing protein 0.0118 0.0253 0.0332
Echinococcus granulosus NDR protein kinase 0.0046 0.0007 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.0663 0.0869
Schistosoma mansoni histone deacetylase hda2 0.019 0.0502 0.0658
Giardia lamblia Kinase, CMGC CDK 0.0147 0.0353 0.1895
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0075 0.0098
Echinococcus multilocularis microtubule associated protein 2 0.0669 0.2155 0.2823
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0053 0.0031 0.0041
Entamoeba histolytica protein kinase, putative 0.0049 0.0018 0.0102
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0091 0.0161 0.0212
Echinococcus granulosus defective proboscis extension response 0.0114 0.0241 0.0316
Loa Loa (eye worm) hypothetical protein 0.0116 0.0249 0.0326
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0059 0.005 0.0066
Trypanosoma cruzi histone deacetylase, putative 0.0383 0.1168 0.5646
Entamoeba histolytica protein kinase, putative 0.0049 0.0018 0.0102
Schistosoma mansoni microtubule-associated protein tau 0.0669 0.2155 0.2823
Loa Loa (eye worm) hypothetical protein 0.0059 0.0051 0.0067
Loa Loa (eye worm) hypothetical protein 0.0203 0.0546 0.0715
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0326 0.1863
Brugia malayi Tyrosine-protein kinase abl-1 0.0373 0.1135 0.1487
Echinococcus granulosus serine:threonine protein kinase N2 0.0046 0.0007 0.0009
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0114 0.0241 0.0316
Schistosoma mansoni protein kinase 0.031 0.0915 0.1199
Echinococcus granulosus histone deacetylase 7 0.0383 0.1168 0.153
Echinococcus granulosus histone deacetylase 6 0.0383 0.1168 0.153
Onchocerca volvulus 0.0077 0.0113 0.0229
Loa Loa (eye worm) hypothetical protein 0.0104 0.0207 0.0271
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0115 0.0243 0.0319
Loa Loa (eye worm) AGC/PKN protein kinase 0.0046 0.0007 0.0009
Echinococcus multilocularis c src tyrosine kinase 0.0084 0.0137 0.018
Echinococcus granulosus histone deacetylase 6 0.0389 0.1188 0.1557
Echinococcus multilocularis dual specificity 0.0195 0.0519 0.0679
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0644 0.2068 1
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0075 0.0098
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.01 0.0191 0.025
Schistosoma mansoni tyrosine kinase 0.0112 0.0235 0.0308
Giardia lamblia Kinase, CK1 Casein kinase 0.0059 0.0051 0.0142
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0046 0.0007 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0139 0.0326 0.0427
Echinococcus multilocularis tyrosine protein kinase Abl 0.0315 0.0934 0.1224
Echinococcus multilocularis cyclin dependent kinase 0.0147 0.0353 0.0463
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0081 0.0129 0.0168
Leishmania major casein kinase, putative 0.0059 0.0051 0.0246
Schistosoma mansoni serine/threonine protein kinase 0.0552 0.1751 0.2294
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0081 0.0128 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.005 0.0066
Schistosoma mansoni cell adhesion molecule 0.0144 0.0344 0.045
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0112 0.0235 0.0308
Loa Loa (eye worm) hypothetical protein 0.019 0.0502 0.0658
Trichomonas vaginalis AGC family protein kinase 0.0552 0.1751 1
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0165 0.0418 0.0548
Loa Loa (eye worm) hypothetical protein 0.0199 0.0534 0.0699
Brugia malayi SH2 domain containing protein 0.0066 0.0075 0.0098
Echinococcus granulosus Protein kinase C brain isozyme 0.0061 0.0057 0.0075
Loa Loa (eye worm) CAMK protein kinase 0.0057 0.0045 0.006
Echinococcus multilocularis histone deacetylase 6 0.0383 0.1168 0.153
Loa Loa (eye worm) TK/EGFR protein kinase 0.2258 0.7634 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.024 0.1159
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0059 0.0051 0.0067
Schistosoma mansoni protein kinase 0.0166 0.0419 0.055
Loa Loa (eye worm) hypothetical protein 0.0172 0.044 0.0577
Echinococcus multilocularis death associated protein kinase 1 0.0809 0.2636 0.3453
Plasmodium falciparum calcium-dependent protein kinase 4 0.0059 0.005 0.0287
Trypanosoma cruzi histone deacetylase, putative 0.019 0.0502 0.2428
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0065 0.0072 0.0408
Loa Loa (eye worm) histone deacetylase 7A 0.0383 0.1168 0.153
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0191 0.025
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0075 0.0098
Echinococcus multilocularis roundabout 2 0.0061 0.0058 0.0077
Echinococcus multilocularis rho associated protein kinase 0.0304 0.0896 0.1174
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0552 0.1751 1
Onchocerca volvulus 0.0757 0.246 0.8167
Echinococcus granulosus hypothetical protein 0.0116 0.0249 0.0326
Schistosoma mansoni histone deacetylase 4 5 0.0383 0.1168 0.153
Schistosoma mansoni kinase 0.0069 0.0084 0.0111
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0059 0.0051 0.0246
Echinococcus granulosus roundabout 2 0.0061 0.0058 0.0077
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0073 0.0099 0.048
Loa Loa (eye worm) TK/FAK protein kinase 0.0289 0.0846 0.1108
Echinococcus granulosus cyclin dependent kinase 9 0.0066 0.0075 0.0098
Echinococcus multilocularis tyrosine protein kinase shark 0.0066 0.0075 0.0098
Entamoeba histolytica protein kinase, putative 0.0552 0.1751 1
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0115 0.0243 0.0319
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0065 0.0072 0.0346
Trypanosoma brucei polo-like protein kinase 0.0114 0.024 0.1159
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.005 0.0287
Schistosoma mansoni cell adhesion molecule 0.0061 0.0058 0.0077
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0112 0.0235 0.0308
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0007 0.0009
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0094 0.0172 0.0226
Echinococcus multilocularis cyclin dependent kinase 9 0.0066 0.0075 0.0098
Brugia malayi Protein kinase domain containing protein 0.0062 0.006 0.0078
Loa Loa (eye worm) hypothetical protein 0.01 0.0191 0.025
Loa Loa (eye worm) hypothetical protein 0.0457 0.1425 0.1867
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0195 0.0519 0.2508
Schistosoma mansoni tyrosine kinase 0.1253 0.417 0.5462
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0007 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0007 0.0009
Loa Loa (eye worm) histone deacetylase 0.0383 0.1168 0.153
Schistosoma mansoni protein kinase 0.0215 0.0589 0.0771
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0115 0.0243 0.1176
Schistosoma mansoni serine/threonine kinase 0.0046 0.0007 0.0009
Echinococcus multilocularis lachesin 0.0058 0.0046 0.0061
Brugia malayi histone deacetylase 1 (HD1) 0.0457 0.1425 0.1867
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0114 0.0241 0.0316
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0061 0.0058 0.0077
Loa Loa (eye worm) hypothetical protein 0.0118 0.0253 0.0332
Trichomonas vaginalis histone deacetylase, putative 0.0457 0.1425 0.8139
Trichomonas vaginalis CK1 family protein kinase 0.0059 0.0051 0.029
Loa Loa (eye worm) hypothetical protein 0.0148 0.036 0.0471
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0075 0.0098
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0147 0.0353 0.1707
Schistosoma mansoni nephrin 0.0061 0.0058 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0161 0.0212
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0033 0.0044
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0059 0.005 0.0243
Giardia lamblia Kinase, STE STE20 0.0165 0.0418 0.2273
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0061 0.0058 0.0077
Giardia lamblia Kinase, CMGC GSK 0.0115 0.0243 0.1257
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0457 0.1425 0.8139
Entamoeba histolytica PH domain containing protein kinase, putative 0.0103 0.0203 0.1157
Brugia malayi cell division control protein 2 homolog 0.0147 0.0353 0.0463
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.024 0.1369
Entamoeba histolytica protein kinase, putative 0.0059 0.005 0.0287
Echinococcus multilocularis histone deacetylase 6 0.0389 0.1188 0.1557
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0137 0.0321 0.042
Echinococcus multilocularis 0.0688 0.2222 0.2911
Echinococcus granulosus casein kinase I delta 0.0059 0.0051 0.0067
Schistosoma mansoni protein kinase 0.0112 0.0233 0.0305
Leishmania major protein kinase A catalytic subunit 0.01 0.0191 0.0924
Trichomonas vaginalis AGC family protein kinase 0.0049 0.0018 0.0102
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0046 0.0061
Trichomonas vaginalis AGC family protein kinase 0.0049 0.0018 0.0102
Loa Loa (eye worm) hypothetical protein 0.0114 0.0241 0.0316
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0077 0.0114 0.0149
Trichomonas vaginalis AGC family protein kinase 0.0049 0.0018 0.0102
Echinococcus granulosus aurora kinase A 0.0552 0.1751 0.2294
Echinococcus multilocularis serine threonine protein kinase 0.0046 0.0007 0.0009
Echinococcus multilocularis mitogen activated protein kinase 11 0.0644 0.2068 0.2709
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.01 0.0191 0.0956
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0227 0.0298
Loa Loa (eye worm) hypothetical protein 0.0073 0.0099 0.013
Echinococcus granulosus insulin receptor 0.085 0.2778 0.3639
Brugia malayi Protein kinase domain containing protein 0.0195 0.0519 0.0679
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0046 0.0007 0.0009
Echinococcus multilocularis Immunoglobulin 0.0114 0.0241 0.0316
Echinococcus granulosus epidermal growth factor receptor 0.1253 0.417 0.5462
Giardia lamblia Kinase, NEK 0.0122 0.0268 0.1401
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0079 0.012 0.0157
Trichomonas vaginalis AGC family protein kinase 0.01 0.0191 0.1092
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0061 0.0058 0.0077
Entamoeba histolytica hypothetical protein 0.0195 0.0519 0.2962
Brugia malayi Tyrosine-protein kinase abl-1 0.0315 0.0934 0.1224
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0444 0.1379 0.1806
Schistosoma mansoni tyrosine kinase 0.01 0.0193 0.0253
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0091 0.0161 0.0212
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0361 0.0473
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0165 0.0418 0.0548
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0268 0.1531
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0195 0.0519 0.2508
Brugia malayi hypothetical protein 0.0066 0.0075 0.0098
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0059 0.005 0.0066
Loa Loa (eye worm) hypothetical protein 0.0274 0.0791 0.1036
Echinococcus multilocularis protein kinase c epsilon type 0.0061 0.0057 0.0075
Brugia malayi Protein kinase domain containing protein 0.0046 0.0007 0.0009
Toxoplasma gondii histone deacetylase HDAC4 0.019 0.0502 0.2867
Plasmodium vivax histone deacetylase, putative 0.0383 0.1168 0.6618
Trypanosoma cruzi cdc2-related kinase 1 0.0147 0.0353 0.1707
Echinococcus multilocularis dual specificity protein kinase clk2 0.0139 0.0326 0.0427
Echinococcus multilocularis roundabout 2 0.0061 0.0058 0.0077
Loa Loa (eye worm) hypothetical protein 0.0115 0.0243 0.0318
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0075 0.0098
Schistosoma mansoni tyrosine kinase 0.0066 0.0075 0.0098
Brugia malayi Immunoglobulin I-set domain containing protein 0.0061 0.0058 0.0077
Echinococcus granulosus tyrosine protein kinase Src64B 0.0112 0.0235 0.0308
Echinococcus granulosus TGF beta receptor type 1 0.0092 0.0164 0.0214
Plasmodium falciparum protein kinase, putative 0.0065 0.0072 0.0408
Echinococcus multilocularis serine:threonine protein kinase 38 0.0046 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.018 0.0468 0.0613
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0114 0.024 0.0314
Echinococcus multilocularis dual specificity mitogen activated protein 0.0165 0.0418 0.0548
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.2944 1 1
Leishmania major protein kinase, putative 0.0552 0.1751 0.8467
Plasmodium falciparum calcium-dependent protein kinase 2 0.0059 0.005 0.0287
Echinococcus multilocularis tyrosine protein kinase Blk 0.0094 0.0172 0.0226
Loa Loa (eye worm) hypothetical protein 0.0061 0.0058 0.0077
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0061 0.0058 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0694 0.0909
Brugia malayi Histone deacetylase family protein 0.0383 0.1168 0.153
Echinococcus multilocularis cyclin dependent kinase 1 0.0147 0.0353 0.0463
Brugia malayi hypothetical protein 0.0205 0.0554 0.0726
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0195 0.0519 0.0679
Brugia malayi Protein kinase domain containing protein 0.0079 0.012 0.0157
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0213 0.0581 0.0761
Echinococcus granulosus dual specificity mitogen activated protein 0.0165 0.0418 0.0548
Trichomonas vaginalis AGC family protein kinase 0.0552 0.1751 1
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0027 0.0035
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0081 0.0129 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0045 0.0059
Schistosoma mansoni vam6/vps39 related 0.0073 0.0099 0.013
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0286 0.0375
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0122 0.0268 0.1531
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0137 0.0321 0.042
Echinococcus multilocularis serine:threonine protein kinase N2 0.0046 0.0007 0.0009
Onchocerca volvulus 0.0066 0.0075 0.01
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0046 0.0007 0.0009
Echinococcus multilocularis roundabout 2 0.0175 0.0452 0.0593
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0059 0.0051 0.0067
Echinococcus granulosus lachesin 0.0058 0.0046 0.0061
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0073 0.0099 0.048
Schistosoma mansoni vesicular amine transporter 0.0114 0.0241 0.0316
Entamoeba histolytica protein kinase, putative 0.0195 0.0519 0.2962
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0058 0.0046 0.0003
Echinococcus multilocularis twitchin 0.0054 0.0033 0.0044
Echinococcus multilocularis hemicentin 1 0.0058 0.0046 0.0061
Plasmodium falciparum casein kinase 1 0.0059 0.0051 0.029
Loa Loa (eye worm) TK protein kinase 0.0071 0.0092 0.012
Trypanosoma cruzi casein kinase, putative 0.0059 0.0051 0.0246
Schistosoma mansoni histone deacetylase 0.0457 0.1425 0.1867
Echinococcus granulosus tyrosine protein kinase Fyn 0.0112 0.0235 0.0308
Onchocerca volvulus 0.0066 0.0075 0.01
Brugia malayi Prion-like- 0.0058 0.0046 0.0061
Loa Loa (eye worm) IKK protein kinase 0.0914 0.3001 0.3932
Giardia lamblia Kinase, NEK 0.0122 0.0268 0.1401
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.01 0.0191 0.0924
Brugia malayi Protein kinase domain containing protein 0.0177 0.0456 0.0598
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0112 0.0235 0.0308
Echinococcus multilocularis cyclin dependent kinase 7 0.0097 0.0181 0.0237
Brugia malayi probable protein kinase 0.0153 0.0376 0.0493
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.031 0.0915 0.1199
Plasmodium vivax glycogen synthase kinase 3, putative 0.0115 0.0243 0.1257
Entamoeba histolytica protein kinase domain containing protein 0.0115 0.0243 0.1389
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0059 0.005 0.0066
Echinococcus granulosus mitogen activated protein kinase 14 0.0644 0.2068 0.2709
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.008 0.0125 0.0163
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0138 0.0324 0.0424
Echinococcus multilocularis tyrosine protein kinase ABL1 0.067 0.216 0.2829
Schistosoma mansoni serine/threonine protein kinase 0.0137 0.0321 0.042
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.01 0.0191 0.1092
Schistosoma mansoni tyrosine kinase 0.1253 0.417 0.5462
Echinococcus multilocularis activated cdc42 kinase 1 0.0203 0.0546 0.0715
Echinococcus granulosus tyrosine protein kinase Lyn 0.0135 0.0312 0.0409
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0097 0.0181 0.0237
Echinococcus multilocularis epidermal growth factor receptor 0.2258 0.7634 1
Giardia lamblia Kinase, AGC PKA 0.01 0.0191 0.0956
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0091 0.0161 0.0212
Schistosoma mansoni protein kinase 0.0153 0.0376 0.0493
Trichomonas vaginalis STE family protein kinase 0.0165 0.0418 0.2389
Loa Loa (eye worm) hypothetical protein 0.0134 0.0309 0.0405
Schistosoma mansoni tyrosine kinase 0.085 0.2778 0.3639
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0139 0.0326 0.1863
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0007 0.0037
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0115 0.0243 0.1176
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0227 0.0298
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1253 0.417 0.5462
Entamoeba histolytica protein kinase domain containing protein 0.0195 0.0519 0.2962
Echinococcus granulosus roundabout 2 0.0175 0.0452 0.0593
Echinococcus granulosus neuroglian 0.0061 0.0058 0.0077
Schistosoma mansoni septate junction protein 0.0058 0.0046 0.0061
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0177 0.0456 0.0598
Schistosoma mansoni tyrosine kinase 0.0286 0.0836 0.1095
Schistosoma mansoni tyrosine kinase 0.2258 0.7634 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0112 0.0235 0.0308
Echinococcus multilocularis 0.0116 0.0249 0.0326
Loa Loa (eye worm) SRC-1 0.0112 0.0235 0.0308
Trypanosoma brucei histone deacetylase 2 0.019 0.0502 0.2428
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0138 0.0324 0.0424
Echinococcus multilocularis activin receptor type 0.0418 0.1291 0.1691
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0134 0.0309 0.0405
Brugia malayi casein kinase 1, delta 0.0059 0.0051 0.0067
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0091 0.0161 0.0212
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0266 0.1519
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.01 0.0191 0.1092
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.011 0.0227 0.0298
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0046 0.0007 0.0009
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0134 0.0309 0.0405
Trypanosoma brucei histone deacetylase, putative 0.0383 0.1168 0.5646
Echinococcus multilocularis titin 0.0057 0.0045 0.006
Trichomonas vaginalis CMGC family protein kinase 0.0147 0.0353 0.2017
Echinococcus multilocularis cyclin dependent kinase 9 0.0074 0.0101 0.0133
Loa Loa (eye worm) hypothetical protein 0.0172 0.0441 0.0578
Trichomonas vaginalis histone deacetylase, putative 0.0457 0.1425 0.8139
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.01 0.0191 0.025
Trichomonas vaginalis AGC family protein kinase 0.0552 0.1751 1
Toxoplasma gondii AGC kinase 0.01 0.0191 0.1092
Onchocerca volvulus 0.0066 0.0075 0.01
Giardia lamblia Kinase, PLK 0.0114 0.024 0.1237
Echinococcus multilocularis 0.008 0.0125 0.0163
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.024 0.1369
Entamoeba histolytica protein kinase domain containing protein 0.0115 0.0243 0.1389
Brugia malayi histone deacetylase 3 (HD3) 0.0457 0.1425 0.1867
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.024 0.1369
Echinococcus granulosus hemicentin 1 0.0058 0.0046 0.0061
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.01 0.0191 0.025
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0075 0.0098
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0061 0.0057 0.0075
Onchocerca volvulus Serine\/threonine kinase homolog 0.0114 0.024 0.0657
Entamoeba histolytica protein kinase domain containing protein 0.0065 0.0072 0.0408
Echinococcus granulosus raf serine:threonine protein kinase 0.0057 0.0045 0.0059
Brugia malayi Protein kinase domain containing protein 0.0184 0.0483 0.0633
Schistosoma mansoni protein kinase 0.0215 0.0589 0.0771
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0075 0.0428
Schistosoma mansoni roundabout 0.0058 0.0046 0.0061
Toxoplasma gondii AGC kinase 0.0046 0.0007 0.0037
Trypanosoma brucei cdc2-related kinase 3 0.0147 0.0353 0.1707
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0205 0.0554 0.0726
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.006 0.0342
Brugia malayi Protein kinase domain containing protein 0.0289 0.0846 0.1108
Brugia malayi hypothetical protein 0.0073 0.0099 0.013
Echinococcus multilocularis histone deacetylase 1 0.0457 0.1425 0.1867
Leishmania major histone deacetylase, putative 0.0457 0.1425 0.6891
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0075 0.0098
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0213 0.0581 0.0761
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0112 0.0235 0.0308
Schistosoma mansoni protein kinase 0.0166 0.0419 0.055
Echinococcus granulosus histone deacetylase 3 0.0457 0.1425 0.1867
Echinococcus granulosus Vam6:Vps39 protein 0.0073 0.0099 0.013
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0061 0.0057 0.0075
Loa Loa (eye worm) AUR protein kinase 0.0552 0.1751 0.2294
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0177 0.0456 0.0598
Echinococcus granulosus dual specificity protein kinase clk2 0.0139 0.0326 0.0427
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0084 0.0136 0.0178
Entamoeba histolytica protein kinase, putative 0.0552 0.1751 1
Trypanosoma brucei casein kinase I, isoform 2 0.0059 0.0051 0.0246
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0095 0.0177 0.0231
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0109 0.0142
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.014 0.0332 0.0435
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0096 0.0179 0.0234
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.024 0.1369
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0138 0.0324 0.0424
Schistosoma mansoni histone deacetylase 4 5 0.0383 0.1168 0.153
Loa Loa (eye worm) hypothetical protein 0.0193 0.0513 0.0672
Brugia malayi Immunoglobulin I-set domain containing protein 0.0118 0.0253 0.0332
Trichomonas vaginalis AGC family protein kinase 0.0552 0.1751 1
Echinococcus granulosus protein tyrosine kinase 0.0286 0.0836 0.1095
Trypanosoma cruzi histone deacetylase 1, putative 0.0457 0.1425 0.6891
Trichomonas vaginalis CAMK family protein kinase 0.0067 0.008 0.0458
Echinococcus multilocularis tyrosine protein kinase otk 0.0058 0.0046 0.0061
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0046 0.0061
Loa Loa (eye worm) histone deacetylase 3 0.0457 0.1425 0.1867
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0147 0.0353 0.2017
Trypanosoma cruzi histone deacetylase 1, putative 0.0457 0.1425 0.6891
Schistosoma mansoni titin 0.0057 0.0045 0.006
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0073 0.0099 0.013
Toxoplasma gondii AGC kinase 0.01 0.0191 0.1092
Loa Loa (eye worm) hypothetical protein 0.0172 0.0441 0.0578
Echinococcus multilocularis mitogen activated protein kinase 14 0.0644 0.2068 0.2709
Loa Loa (eye worm) hypothetical protein 0.0062 0.006 0.0079
Brugia malayi Protein kinase domain containing protein 0.0049 0.0018 0.0023
Onchocerca volvulus 0.0134 0.0309 0.0892
Trichomonas vaginalis CAMK family protein kinase 0.0067 0.008 0.0458
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0552 0.1751 0.2294
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0059 0.005 0.0066
Brugia malayi Cam kinase protein 1 0.0059 0.005 0.0066
Trypanosoma brucei protein kinase, putative 0.0065 0.0072 0.0346
Echinococcus multilocularis tyrosine kinase 0.0066 0.0075 0.0098
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0147 0.0353 0.0463
Toxoplasma gondii histone deacetylase HDAC3 0.0457 0.1425 0.8139
Plasmodium vivax casein kinase 1, putative 0.0059 0.0051 0.0142
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0046 0.0061
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0115 0.0243 0.0319
Trypanosoma brucei histone deacetylase 4 0.0383 0.1168 0.5646
Schistosoma mansoni tyrosine kinase 0.085 0.2778 0.3639
Trichomonas vaginalis histone deacetylase, putative 0.0457 0.1425 0.8139
Echinococcus multilocularis casein kinase I alpha 0.0059 0.0051 0.0067
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0112 0.0235 0.0308
Entamoeba histolytica protein kinase domain containing protein 0.0552 0.1751 1
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0045 0.006
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.01 0.0191 0.025
Echinococcus granulosus protein kinase shaggy 0.0115 0.0243 0.0319
Leishmania major histone deacetylase, putative 0.0383 0.1168 0.5646
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0147 0.0353 0.0463
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0139 0.0326 0.1577
Trypanosoma cruzi histone deacetylase, putative 0.0383 0.1168 0.5646
Echinococcus multilocularis mitogen activated protein kinase 14 0.0644 0.2068 0.2709
Toxoplasma gondii casein kinase I 0.0059 0.0051 0.029
Echinococcus multilocularis insulin receptor 0.085 0.2778 0.3639
Plasmodium falciparum calcium-dependent protein kinase 1 0.0059 0.005 0.0287
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0077 0.0114 0.0149
Brugia malayi protein C17H12.11 0.0059 0.0051 0.0067
Brugia malayi bone morphogenetic protein type 1 receptor 0.0112 0.0233 0.0305
Echinococcus multilocularis casein kinase I delta 0.0059 0.0051 0.0067
Echinococcus granulosus tyrosine protein kinase Blk 0.0094 0.0172 0.0226
Loa Loa (eye worm) TK/INSR protein kinase 0.085 0.2778 0.3639
Plasmodium falciparum calcium-dependent protein kinase 5 0.0059 0.005 0.0287
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0059 0.0052 0.0067
Loa Loa (eye worm) TK protein kinase 0.017 0.0432 0.0566
Echinococcus granulosus contactin 0.0061 0.0058 0.0077
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0059 0.0051 0.0067
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0059 0.005 0.0066
Schistosoma mansoni rap gtpase-activating protein 0.0073 0.0099 0.013
Echinococcus granulosus microtubule associated protein 2 0.0669 0.2155 0.2823
Trypanosoma brucei protein kinase, putative 0.0115 0.0243 0.1176
Echinococcus multilocularis epidermal growth factor receptor 0.1253 0.417 0.5462
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0059 0.005 0.0066
Schistosoma mansoni histone deacetylase hda2 0.0389 0.1188 0.1557
Echinococcus multilocularis peroxidasin 0.0058 0.0048 0.0062
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.01 0.0191 0.0924
Onchocerca volvulus 0.0304 0.0896 0.2879
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0107 0.0216 0.1045
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.01 0.0191 0.025
Brugia malayi Protein kinase domain containing protein 0.0538 0.1704 0.2232
Onchocerca volvulus 0.0066 0.0075 0.01
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0059 0.005 0.0287
Brugia malayi Protein kinase domain containing protein 0.0203 0.0546 0.0715
Echinococcus granulosus TGF-beta receptor type-1 0.0092 0.0164 0.0214
Loa Loa (eye worm) hypothetical protein 0.0059 0.0051 0.0067
Onchocerca volvulus 0.0115 0.0243 0.0669
Onchocerca volvulus 0.0282 0.0819 0.2617
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0104 0.0207 0.0271
Entamoeba histolytica protein kinase , putative 0.0552 0.1751 1
Giardia lamblia Kinase, NEK 0.0122 0.0268 0.1401
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0195 0.0519 0.2508
Echinococcus granulosus tyrosine protein kinase Fyn 0.0112 0.0235 0.0308
Plasmodium falciparum calcium-dependent protein kinase 3 0.0059 0.005 0.0287
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0134 0.0309 0.0405
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0127 0.0286 0.0375
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0066 0.0075 0.0428
Echinococcus multilocularis neuroglian 0.0061 0.0058 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0027 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.094 0.309 0.4048
Loa Loa (eye worm) TK/KIN16 protein kinase 0.094 0.309 0.4048
Echinococcus granulosus histone deacetylase 0.0383 0.1168 0.153
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0104 0.0205 0.0268
Trichomonas vaginalis histone deacetylase, putative 0.0457 0.1425 0.8139
Echinococcus multilocularis transfer RNA-Thr 0.0203 0.0546 0.0715
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0059 0.005 0.0066
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0205 0.0554 0.0726
Echinococcus granulosus twitchin 0.0168 0.0427 0.056
Echinococcus multilocularis histone deacetylase 6 0.0383 0.1168 0.153
Brugia malayi cyclin-dependent kinase 7 homolog 0.0104 0.0207 0.0271
Loa Loa (eye worm) hypothetical protein 0.0134 0.0309 0.0405
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0137 0.0321 0.042
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.01 0.0191 0.0924
Trypanosoma cruzi aurora B kinase, putative 0.0552 0.1751 0.8467
Echinococcus granulosus cyclin dependent kinase 19 0.0149 0.0361 0.0473
Echinococcus multilocularis protein tyrosine kinase 0.0286 0.0836 0.1095
Echinococcus granulosus roundabout 2 0.0061 0.0058 0.0077
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0046 0.0007 0.0009
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0552 0.1751 1
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0205 0.0554 0.0726
Brugia malayi SRC-1 0.0112 0.0235 0.0308
Brugia malayi protein kinase C II. 0.0061 0.0057 0.0075
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0107 0.0217 0.0284
Treponema pallidum licC protein (licC) 0.054 0.1709 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0007 0.0009
Echinococcus multilocularis tyrosine protein kinase HCK 0.0071 0.0092 0.012
Leishmania major protein kinase, putative 0.0139 0.0326 0.1577
Schistosoma mansoni protein kinase 0.0165 0.0418 0.0548
Schistosoma mansoni histone deacetylase 0.0457 0.1425 0.1867
Brugia malayi P38 map kinase family protein 2 0.0644 0.2068 0.2709
Echinococcus multilocularis TGF beta receptor type 1 0.0092 0.0164 0.0214
Echinococcus multilocularis cyclin dependent kinase 19 0.0149 0.0361 0.0473
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0139 0.0326 0.1577
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0243 0.1389
Trichomonas vaginalis CMGC family protein kinase 0.0147 0.0353 0.2017

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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