Detailed information for compound 1738319

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 380.821 | Formula: C22H17ClO4
  • H donors: 1 H acceptors: 2 LogP: 6.35 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc2c(c1)c(CCCOc1cccc3c1cccc3)c(o2)C(=O)O
  • InChi: 1S/C22H17ClO4/c23-15-10-11-20-18(13-15)17(21(27-20)22(24)25)8-4-12-26-19-9-3-6-14-5-1-2-7-16(14)19/h1-3,5-7,9-11,13H,4,8,12H2,(H,24,25)
  • InChiKey: DFAAJPMWSDOXJL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens myeloid cell leukemia 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0064 0.0237 0.0456
Entamoeba histolytica tyrosin kinase, putative 0.0043 0.0035 0.0076
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0471 0.4203 0.4477
Entamoeba histolytica protein kinase, putative 0.004 0.0012 0.0023
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0078 0.0381 0.0803
Brugia malayi Protein kinase domain containing protein 0.0962 0.8972 0.8967
Echinococcus multilocularis tyrosine protein kinase HCK 0.0066 0.0258 0.0227
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0138 0.0961 0.0984
Entamoeba histolytica PH domain containing protein kinase, putative 0.0107 0.0661 0.1566
Echinococcus multilocularis cyclin dependent kinase 9 0.0067 0.0274 0.0245
Trichomonas vaginalis CAMK family protein kinase 0.0119 0.0773 0.1747
Schistosoma mansoni tyrosine kinase 0.025 0.2051 0.2159
Schistosoma mansoni serine/threonine protein kinase 0.0194 0.1509 0.1575
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.012 0.0784 0.1772
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0146 0.0099
Echinococcus multilocularis aurora kinase A 0.0471 0.4203 0.4477
Loa Loa (eye worm) hypothetical protein 0.0185 0.1417 0.1376
Echinococcus granulosus twitchin 0.0171 0.1284 0.1333
Loa Loa (eye worm) hypothetical protein 0.0074 0.0342 0.0296
Schistosoma mansoni serine/threonine kinase 0.0061 0.0207 0.0172
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0067 0.0274 0.0228
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0173 0.0136
Echinococcus granulosus serine:threonine protein kinase 0.0063 0.0229 0.0195
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0144 0.1018 0.1046
Brugia malayi protein unc-22 0.0057 0.0173 0.0127
Loa Loa (eye worm) gastrulation defective protein 1 0.0136 0.0939 0.0896
Echinococcus multilocularis serine:threonine protein kinase 0.0063 0.0229 0.0195
Schistosoma mansoni tyrosine kinase 0.0579 0.5246 0.5601
Schistosoma mansoni kinase 0.007 0.0303 0.0275
Loa Loa (eye worm) AUR protein kinase 0.0471 0.4203 0.4175
Loa Loa (eye worm) hypothetical protein 0.0117 0.0761 0.0717
Trichomonas vaginalis histone deacetylase, putative 0.0064 0.0237 0.0456
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0536 0.0527
Brugia malayi SRC-1 0.0098 0.057 0.0525
Echinococcus granulosus tyrosine protein kinase Fyn 0.0098 0.057 0.0563
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0217 0.1725 0.1686
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.006 0.02 0.0164
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0146 0.1035 0.0992
Trichomonas vaginalis histone deacetylase, putative 0.0064 0.0237 0.0456
Plasmodium vivax histone deacetylase 1, putative 0.0064 0.0237 0.027
Echinococcus multilocularis cyclin dependent kinase 1 0.011 0.0684 0.0686
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.026 0.2149 0.2111
Echinococcus granulosus rho-associated protein kinase 1 0.0323 0.2762 0.2924
Echinococcus granulosus activin receptor type 0.0436 0.3855 0.4103
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0146 0.0099
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0059 0.0195 0.0148
Loa Loa (eye worm) hypothetical protein 0.006 0.0199 0.0152
Trypanosoma brucei histone deacetylase 1 0.0064 0.0237 0.0456
Entamoeba histolytica protein kinase, putative 0.0066 0.0258 0.0608
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0174 0.1314 0.3126
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0186 0.1429 0.1489
Echinococcus multilocularis hemicentin 1 0.0059 0.0195 0.0159
Trypanosoma brucei casein kinase I, isoform 2 0.006 0.0201 0.037
Trichomonas vaginalis CAMK family protein kinase 0.0119 0.0773 0.1747
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.1035 0.2377
Echinococcus multilocularis microtubule associated protein 2 0.0718 0.6605 0.7066
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0146 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.1114 0.1149
Loa Loa (eye worm) CAMK/PKD protein kinase 0.01 0.0589 0.0545
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0144 0.1018 0.0975
Trichomonas vaginalis CAMK family protein kinase 0.006 0.02 0.0367
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0104 0.0626 0.1393
Echinococcus granulosus tyrosine protein kinase Src64B 0.0098 0.057 0.0563
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0059 0.0195 0.0159
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0195 0.0148
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0078 0.0381 0.036
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0194 0.1509 0.1575
Onchocerca volvulus 0.0054 0.0146 0.016
Loa Loa (eye worm) hypothetical protein 0.0063 0.0229 0.0182
Echinococcus multilocularis serine:threonine protein kinase N2 0.0046 0.0067 0.0021
Schistosoma mansoni protein kinase 0.0329 0.2818 0.2985
Loa Loa (eye worm) hypothetical protein 0.0145 0.1025 0.0982
Echinococcus granulosus insulin receptor 0.0455 0.4048 0.431
Echinococcus multilocularis Immunoglobulin 0.0118 0.0766 0.0774
Plasmodium falciparum calcium-dependent protein kinase 3 0.006 0.02 0.0367
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0054 0.0146 0.0106
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0773 0.0782
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.006 0.02 0.0367
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.014 0.0984 0.0942
Echinococcus granulosus tyrosine protein kinase ABL1 0.0269 0.2234 0.2356
Onchocerca volvulus Tyrosine kinase homolog 0.0955 0.8911 0.9755
Leishmania major protein kinase, putative 0.006 0.02 0.0367
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0146 0.1035 0.2377
Onchocerca volvulus 0.0323 0.2762 0.3023
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0068 0.028 0.0251
Echinococcus multilocularis tyrosine kinase 0.0054 0.0146 0.0106
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0471 0.4203 0.4477
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0128 0.0194
Onchocerca volvulus 0.0302 0.2561 0.2803
Schistosoma mansoni hypothetical protein 0.01 0.0591 0.0586
Plasmodium falciparum serine/threonine protein kinase, putative 0.0471 0.4203 1
Toxoplasma gondii aurora kinase 0.0471 0.4203 1
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0174 0.1314 0.3048
Echinococcus multilocularis 0.0125 0.0834 0.0848
Echinococcus multilocularis c Jun NH2 terminal kinase 0.026 0.2149 0.2264
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0081 0.0411 0.0365
Brugia malayi Protein kinase domain containing protein 0.0146 0.1035 0.0992
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0217 0.1725 0.1808
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0471 0.4203 1
Plasmodium vivax glycogen synthase kinase 3, putative 0.012 0.0784 0.1611
Echinococcus multilocularis cyclin dependent kinase 9 0.0076 0.0354 0.033
Loa Loa (eye worm) IKK protein kinase 0.0979 0.9135 0.9131
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0099 0.0582 0.0576
Echinococcus multilocularis protein KINase family member (kin 25) 0.0102 0.0606 0.0603
Onchocerca volvulus 0.0054 0.0146 0.016
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0078 0.0381 0.0907
Schistosoma mansoni microtubule-associated protein tau 0.0718 0.6605 0.7066
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0206 0.1618 0.3779
Loa Loa (eye worm) AUR protein kinase 0.0471 0.4203 0.4175
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0104 0.0626 0.1393
Echinococcus multilocularis dual specificity protein kinase clk2 0.0146 0.1035 0.1064
Loa Loa (eye worm) hypothetical protein 0.0078 0.0381 0.0335
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0146 0.0099
Echinococcus granulosus serine:threonine protein kinase N2 0.0046 0.0067 0.0021
Schistosoma mansoni protein kinase 0.0175 0.1317 0.1369
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0186 0.1429 0.1388
Brugia malayi Immunoglobulin I-set domain containing protein 0.0057 0.0173 0.0127
Echinococcus multilocularis dual specificity 0.0206 0.1618 0.1692
Loa Loa (eye worm) apoptosis regulator protein 0.01 0.0591 0.0547
Loa Loa (eye worm) histone deacetylase 3 0.0064 0.0237 0.0191
Loa Loa (eye worm) CMGC/GSK protein kinase 0.012 0.0784 0.074
Echinococcus granulosus glycogen synthase kinase 3 beta 0.012 0.0784 0.0793
Echinococcus multilocularis dual specificity mitogen activated protein 0.0174 0.1314 0.1365
Brugia malayi Protein kinase domain containing protein 0.0054 0.0146 0.0099
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0104 0.0626 0.1393
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0084 0.0436 0.0391
Echinococcus multilocularis raf serine:threonine protein kinase 0.0051 0.0116 0.0074
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0098 0.057 0.0563
Entamoeba histolytica protein kinase, putative 0.005 0.0102 0.0235
Brugia malayi Temporarily assigned gene name protein 59 0.0078 0.0381 0.0335
Trypanosoma brucei rac serine-threonine kinase, putative 0.005 0.0102 0.0131
Brugia malayi Protein kinase domain containing protein 0.0063 0.0229 0.0182
Brugia malayi Protein kinase domain containing protein 0.0329 0.2818 0.2784
Brugia malayi Protein kinase domain containing protein 0.03 0.2541 0.2506
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0063 0.0231 0.0198
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.022 0.0186
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0104 0.0626 0.1393
Echinococcus granulosus protein kinase c iota type 0.0062 0.022 0.0186
Entamoeba histolytica serine/threonine protein kinase, putative 0.0044 0.0047 0.0106
Brugia malayi Protein kinase domain containing protein 0.005 0.0102 0.0055
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0046 0.0067 0.002
Loa Loa (eye worm) hypothetical protein 0.0089 0.0483 0.0438
Echinococcus granulosus cyclin dependent kinase 19 0.0156 0.114 0.1178
Entamoeba histolytica protein kinase, putative 0.006 0.02 0.0469
Loa Loa (eye worm) hypothetical protein 0.0118 0.0766 0.0722
Leishmania major protein kinase, putative 0.0146 0.1035 0.2377
Schistosoma mansoni serine/threonine protein kinase 0.0323 0.2762 0.2924
Echinococcus granulosus tyrosine protein kinase HCK 0.0066 0.0258 0.0227
Schistosoma mansoni tyrosine kinase 0.0067 0.0275 0.0245
Loa Loa (eye worm) AUR protein kinase 0.0471 0.4203 0.4175
Loa Loa (eye worm) hypothetical protein 0.01 0.0591 0.0547
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0104 0.0626 0.149
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.1429 0.1489
Echinococcus multilocularis mitogen activated protein kinase 11 0.0151 0.109 0.1124
Echinococcus multilocularis serine:threonine protein kinase 0.0063 0.0229 0.0195
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0094 0.0536 0.0527
Echinococcus granulosus cyclin dependent kinase 7 0.01 0.0595 0.059
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.025 0.0218
Entamoeba histolytica protein kinase, putative 0.0471 0.4203 1
Trichomonas vaginalis AGC family protein kinase 0.0471 0.4203 1
Schistosoma mansoni nephrin 0.0063 0.0231 0.0198
Plasmodium falciparum protein kinase, putative 0.0056 0.0164 0.0281
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0269 0.2234 0.2356
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0151 0.109 0.1048
Echinococcus multilocularis protein kinase shaggy 0.012 0.0784 0.0793
Echinococcus granulosus dual specificity protein kinase clk2 0.0146 0.1035 0.1064
Brugia malayi Cam kinase protein 1 0.006 0.02 0.0153
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0329 0.2818 0.2784
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.006 0.02 0.0178
Loa Loa (eye worm) hypothetical protein 0.0059 0.0195 0.0148
Echinococcus granulosus cyclin dependent kinase 1 0.011 0.0684 0.0686
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0217 0.1729 0.1812
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.014 0.0984 0.0942
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0329 0.2818 0.2985
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0144 0.1018 0.0975
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0206 0.1618 0.1692
Brugia malayi Histone deacetylase 1 0.0064 0.0237 0.0191
Trichomonas vaginalis CMGC family protein kinase 0.012 0.0784 0.1772
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0067 0.0021
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.01 0.0591 0.0586
Trypanosoma cruzi cdc2-related kinase 1 0.011 0.0684 0.1628
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.1035 0.1064
Onchocerca volvulus 0.0054 0.0146 0.016
Echinococcus granulosus TGF-beta receptor type-1 0.0095 0.0543 0.0534
Trypanosoma cruzi polo-like protein kinase, putative 0.0119 0.0773 0.184
Echinococcus multilocularis cyclin dependent kinase 19 0.0156 0.114 0.1178
Schistosoma mansoni tyrosine kinase 0.0543 0.4902 0.5231
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.006 0.02 0.0367
Echinococcus multilocularis c src tyrosine kinase 0.0067 0.0275 0.0245
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0133 0.0914 0.0871
Loa Loa (eye worm) hypothetical protein 0.0104 0.0626 0.0582
Echinococcus multilocularis neuroglian 0.0151 0.1083 0.1116
Echinococcus granulosus tyrosine protein kinase otk 0.0059 0.0195 0.0159
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0471 0.4203 1
Echinococcus granulosus activated cdc42 kinase 1 0.0207 0.1634 0.171
Brugia malayi Protein kinase domain containing protein 0.0156 0.114 0.1098
Schistosoma mansoni rap gtpase-activating protein 0.0078 0.0381 0.036
Entamoeba histolytica protein kinase domain containing protein 0.012 0.0784 0.1859
Schistosoma mansoni tyrosine kinase 0.0067 0.0275 0.0245
Trichomonas vaginalis AGC family protein kinase 0.0471 0.4203 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0235 0.0189
Echinococcus granulosus casein kinase I alpha 0.006 0.0201 0.0166
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0078 0.0381 0.0907
Trichomonas vaginalis AGC family protein kinase 0.005 0.0102 0.0131
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0094 0.0536 0.0527
Loa Loa (eye worm) TK/INSR protein kinase 0.0455 0.4048 0.4019
Trichomonas vaginalis AGC family protein kinase 0.005 0.0102 0.0131
Trypanosoma cruzi cdc2-related kinase 1 0.011 0.0684 0.1628
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0083 0.0425 0.038
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.011 0.0686 0.0641
Echinococcus granulosus lachesin 0.0059 0.0195 0.0159
Trichomonas vaginalis STE family protein kinase 0.0174 0.1314 0.3048
Schistosoma mansoni protein kinase 0.0095 0.0543 0.0534
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0063 0.0231 0.0198
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0104 0.0626 0.0624
Brugia malayi Serine/threonine-protein kinase SULU 0.0217 0.1725 0.1686
Schistosoma mansoni tyrosine kinase 0.0998 0.9329 1
Leishmania major casein kinase, putative 0.006 0.0201 0.037
Brugia malayi Protein kinase domain containing protein 0.011 0.0686 0.0641
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0056 0.0164 0.039
Trichomonas vaginalis CAMK family protein kinase 0.0069 0.029 0.0585
Onchocerca volvulus 0.0054 0.0146 0.016
Echinococcus multilocularis casein kinase I alpha 0.006 0.0201 0.0166
Echinococcus multilocularis cyclin dependent kinase 1 0.011 0.0684 0.0686
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0104 0.0626 0.149
Entamoeba histolytica protein kinase, putative 0.004 0.0012 0.0023
Loa Loa (eye worm) TK/ROR protein kinase 0.0068 0.028 0.0234
Schistosoma mansoni vesicular amine transporter 0.0118 0.0766 0.0774
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0914 0.0934
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0056 0.0164 0.039
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0068 0.028 0.0251
Loa Loa (eye worm) AGC/PKN protein kinase 0.0046 0.0067 0.002
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0078 0.0381 0.036
Echinococcus granulosus cyclin dependent kinase 9 0.0067 0.0274 0.0245
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0151 0.109 0.251
Schistosoma mansoni atypical protein kinase C 0.0062 0.022 0.0186
Leishmania major histone deacetylase, putative 0.0064 0.0237 0.0456
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0067 0.0021
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0119 0.0773 0.0782
Brugia malayi protein-tyrosine kinase 0.0085 0.0441 0.0396
Loa Loa (eye worm) CMGC/GSK protein kinase 0.012 0.0784 0.074
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0151 0.109 0.2594
Echinococcus granulosus mitogen activated protein kinase 11 0.0151 0.109 0.1124
Brugia malayi C1-like domain containing protein 0.01 0.0589 0.0545
Brugia malayi Protein kinase domain containing protein 0.0455 0.4048 0.4019
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.006 0.0201 0.0155
Schistosoma mansoni hypothetical protein 0.01 0.0591 0.0586
Schistosoma mansoni protein kinase 0.0217 0.1729 0.1812
Echinococcus multilocularis calcium activated potassium channel 0.0052 0.0128 0.0087
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0626 0.1393
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0119 0.0773 0.0782
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0118 0.0766 0.0774
Trypanosoma cruzi casein kinase, putative 0.006 0.0201 0.0478
Brugia malayi Protein kinase domain containing protein 0.0194 0.1509 0.1469
Brugia malayi serine/threonine protein kinase 6 0.0471 0.4203 0.4175
Onchocerca volvulus 0.0888 0.825 0.9031
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0684 0.1533
Echinococcus multilocularis rho associated protein kinase 0.0323 0.2762 0.2924
Loa Loa (eye worm) hypothetical protein 0.0207 0.1634 0.1595
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0056 0.0164 0.0281
Trichomonas vaginalis AGC family protein kinase 0.005 0.0102 0.0131
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0054 0.0146 0.0106
Schistosoma mansoni apoptosis regulator bax 0.01 0.0591 0.0586
Schistosoma mansoni protein kinase 0.0083 0.0425 0.0407
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0595 0.059
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0104 0.0626 0.1393
Echinococcus granulosus histone deacetylase 1 0.0064 0.0237 0.0204
Loa Loa (eye worm) hypothetical protein 0.0159 0.1169 0.1127
Leishmania major protein kinase, putative 0.0056 0.0164 0.0281
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0056 0.0164 0.0281
Brugia malayi casein kinase 1, delta 0.006 0.0201 0.0155
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0084 0.0436 0.0391
Echinococcus multilocularis mitogen activated protein kinase 11 0.0151 0.109 0.1124
Entamoeba histolytica protein kinase, putative 0.012 0.0784 0.1859
Trypanosoma brucei protein kinase, putative 0.0056 0.0164 0.0281
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0137 0.0097
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0206 0.1618 0.3849
Entamoeba histolytica protein kinase domain containing protein 0.0043 0.0035 0.0076
Loa Loa (eye worm) TK/FAK protein kinase 0.03 0.2541 0.2506
Schistosoma mansoni histone deacetylase 0.0064 0.0237 0.0204
Brugia malayi Prion-like- 0.0059 0.0195 0.0148
Leishmania major protein kinase, putative 0.0146 0.1035 0.2377
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0102 0.0606 0.0603
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0052 0.0128 0.0081
Loa Loa (eye worm) hypothetical protein 0.0059 0.0195 0.0148
Plasmodium vivax calcium-dependent protein kinase, putative 0.006 0.02 0.0178
Schistosoma mansoni cell adhesion molecule 0.0063 0.0231 0.0198
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0104 0.0626 0.149
Echinococcus granulosus roundabout 2 0.0181 0.1378 0.1434
Schistosoma mansoni protein kinase 0.011 0.0686 0.0688
Trypanosoma cruzi polo-like protein kinase, putative 0.0119 0.0773 0.184
Leishmania major protein kinase A catalytic subunit isoform 1 0.0104 0.0626 0.1393
Loa Loa (eye worm) AGC/PKA protein kinase 0.0104 0.0626 0.0582
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0127 0.0859 0.1953
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.011 0.0684 0.1533
Echinococcus multilocularis roundabout 2 0.0181 0.1378 0.1434
Schistosoma mansoni protein kinase 0.006 0.0201 0.0166
Schistosoma mansoni tyrosine kinase 0.0098 0.057 0.0563
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0044 0.0047 0.0112
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0108 0.0667 0.0622
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0104 0.0626 0.0624
Schistosoma mansoni roundabout 0.0059 0.0195 0.0159
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0557 0.5032 1
Brugia malayi protein C17H12.11 0.0063 0.0235 0.0189
Giardia lamblia Aurora kinase 0.0471 0.4203 1
Trypanosoma brucei protein kinase, putative 0.012 0.0784 0.1772
Entamoeba histolytica protein kinase domain containing protein 0.0471 0.4203 1
Brugia malayi Peroxidasin 0.006 0.0199 0.0152
Echinococcus multilocularis transfer RNA-Thr 0.0207 0.1634 0.171
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0154 0.1114 0.1072
Schistosoma mansoni tyrosine kinase 0.0579 0.5246 0.5601
Loa Loa (eye worm) hypothetical protein 0.0118 0.077 0.0726
Echinococcus granulosus tyrosine protein kinase Fyn 0.0098 0.057 0.0563
Schistosoma mansoni tyrosine kinase 0.0194 0.1505 0.157
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0853 0.1938
Echinococcus multilocularis cyclin dependent kinase 7 0.01 0.0595 0.059
Brugia malayi Protein kinase domain containing protein 0.0046 0.0067 0.002
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0059 0.0195 0.0159
Entamoeba histolytica casein kinase, putative 0.006 0.0201 0.0472
Echinococcus multilocularis serine:threonine protein kinase N2 0.0046 0.0067 0.0021
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0118 0.0766 0.0774
Echinococcus multilocularis epidermal growth factor receptor 0.0998 0.9329 1
Trichomonas vaginalis histone deacetylase, putative 0.0064 0.0237 0.0456
Loa Loa (eye worm) TK protein kinase 0.0066 0.0258 0.0212
Brugia malayi Protein kinase domain containing protein 0.0568 0.5141 0.5117
Echinococcus granulosus casein kinase I delta 0.006 0.0201 0.0166
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0098 0.057 0.0563
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.1035 0.1064
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0146 0.0099
Echinococcus granulosus microtubule associated protein 2 0.0718 0.6605 0.7066
Plasmodium vivax serine/threonine kinase-1, putative 0.0146 0.1035 0.2228
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.1618 0.1692
Loa Loa (eye worm) hypothetical protein 0.0054 0.0146 0.0099
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0175 0.1317 0.1369
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.01 0.0591 0.0586
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0174 0.1314 0.1273
Echinococcus granulosus c src tyrosine kinase 0.0067 0.0275 0.0245
Trichomonas vaginalis AGC family protein kinase 0.0471 0.4203 1
Giardia lamblia Histone deacetylase 0.0064 0.0237 0.027
Brugia malayi Immunoglobulin I-set domain containing protein 0.0122 0.0802 0.0759
Echinococcus multilocularis tyrosine protein kinase Srms 0.0085 0.0441 0.0424
Echinococcus granulosus tyrosine protein kinase shark 0.0054 0.0146 0.0106
Trypanosoma brucei polo-like protein kinase 0.0119 0.0773 0.1747
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0062 0.022 0.0173
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0098 0.057 0.0563
Brugia malayi SH2 domain containing protein 0.0054 0.0146 0.0099
Echinococcus multilocularis tyrosine protein kinase shark 0.0054 0.0146 0.0106
Trichomonas vaginalis STE family protein kinase 0.0127 0.0859 0.1953
Echinococcus multilocularis 0.0299 0.2523 0.2668
Trypanosoma cruzi casein kinase, putative 0.006 0.0201 0.0478
Schistosoma mansoni tyrosine kinase 0.0297 0.2511 0.2654
Toxoplasma gondii AGC kinase 0.0046 0.0067 0.0047
Loa Loa (eye worm) hypothetical protein 0.0118 0.0766 0.0722
Echinococcus granulosus defective proboscis extension response 0.0118 0.0766 0.0774
Onchocerca volvulus 0.0079 0.0388 0.0425
Echinococcus multilocularis casein kinase I delta 0.006 0.0201 0.0166
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0095 0.0543 0.0534
Entamoeba histolytica protein kinase , putative 0.0471 0.4203 1
Schistosoma mansoni nephrin 0.0154 0.1119 0.1155
Leishmania major protein kinase A catalytic subunit 0.0104 0.0626 0.1393
Giardia lamblia Kinase, CK1 Casein kinase 0.006 0.0201 0.0182
Echinococcus multilocularis tyrosine protein kinase Abl 0.015 0.1073 0.1105
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0146 0.0099
Entamoeba histolytica protein kinase, putative 0.0206 0.1618 0.3845
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0067 0.0047
Brugia malayi p70 ribosomal S6 kinase beta 0.0046 0.0067 0.002
Schistosoma mansoni protein kinase 0.0175 0.1317 0.1369
Echinococcus granulosus protein kinase C gamma type 0.0046 0.0067 0.0021
Loa Loa (eye worm) hypothetical protein 0.0503 0.4509 0.4483
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0626 0.0624
Giardia lamblia Kinase, AGC PKA 0.0104 0.0626 0.1225
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.014 0.0984 0.101
Onchocerca volvulus 0.006 0.0201 0.022
Schistosoma mansoni cell adhesion molecule 0.0148 0.1061 0.1092
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0094 0.0536 0.0527
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0195 0.0148
Entamoeba histolytica protein kinase, putative 0.0206 0.1618 0.3845
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0557 0.5032 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0119 0.0773 0.0729
Brugia malayi SH2 domain containing protein 0.0054 0.0146 0.0099
Schistosoma mansoni protein kinase 0.0471 0.4203 0.4477
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0104 0.0626 0.0624
Echinococcus multilocularis casein kinase i 0.006 0.0201 0.0166
Echinococcus multilocularis serine threonine protein kinase 0.0046 0.0067 0.0021
Loa Loa (eye worm) SRC-1 0.0098 0.057 0.0525
Schistosoma mansoni hypothetical protein 0.01 0.0591 0.0586
Echinococcus granulosus protein tyrosine kinase 0.0297 0.2511 0.2654
Schistosoma mansoni tyrosine kinase 0.0543 0.4902 0.5231
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0128 0.0087
Schistosoma mansoni serine/threonine protein kinase 0.006 0.02 0.0164
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0195 0.0148
Echinococcus multilocularis insulin receptor 0.0455 0.4048 0.431
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0626 0.0624
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.011 0.0684 0.064
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0133 0.0914 0.0934
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0078 0.0381 0.036
Trypanosoma cruzi cdc2-related kinase 3 0.011 0.0684 0.1628
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0536 0.0527
Brugia malayi Protein kinase domain containing protein 0.0084 0.0436 0.0391
Echinococcus granulosus Protein kinase C brain isozyme 0.0062 0.022 0.0186
Loa Loa (eye worm) CAMK protein kinase 0.0057 0.0173 0.0127
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.006 0.02 0.0153
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0063 0.0231 0.0185
Entamoeba histolytica hypothetical protein 0.0206 0.1618 0.3845
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0146 0.1035 0.2463
Echinococcus multilocularis casein kinase I alpha 0.006 0.0201 0.0166
Schistosoma mansoni serine/threonine kinase 0.0046 0.0067 0.0021
Trichomonas vaginalis AGC family protein kinase 0.0471 0.4203 1
Echinococcus granulosus mitogen activated protein kinase 14 0.0151 0.109 0.1124
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0062 0.022 0.0186
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0684 0.1533
Echinococcus multilocularis G protein coupled receptor kinase 6 0.014 0.0984 0.101
Loa Loa (eye worm) hypothetical protein 0.0144 0.1016 0.0974
Loa Loa (eye worm) hypothetical protein 0.0059 0.0195 0.0148
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0156 0.114 0.1098
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0735 0.0741
Echinococcus multilocularis mitogen activated protein kinase 14 0.0151 0.109 0.1124
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0174 0.1314 0.3048
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.0229 0.0436
Schistosoma mansoni titin 0.0057 0.0173 0.0136
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.006 0.02 0.0164
Loa Loa (eye worm) hypothetical protein 0.0066 0.0263 0.0216
Loa Loa (eye worm) hypothetical protein 0.0102 0.0606 0.0562
Echinococcus granulosus tyrosine protein kinase Srms 0.0054 0.0146 0.0106
Brugia malayi Protein kinase domain containing protein 0.0979 0.9135 0.9131
Giardia lamblia Kinase, STE STE20 0.0174 0.1314 0.2912
Echinococcus granulosus serine:threonine protein kinase 0.0063 0.0229 0.0195
Trichomonas vaginalis CAMK family protein kinase 0.0119 0.0773 0.1747
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0735 0.0741
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0194 0.1509 0.1575
Echinococcus granulosus calcium activated potassium channel 0.0052 0.0128 0.0087
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0144 0.1018 0.1046
Onchocerca volvulus 0.0979 0.9135 1
Brugia malayi protein kinase C II. 0.0062 0.022 0.0173
Plasmodium falciparum calcium-dependent protein kinase 4 0.006 0.02 0.0367
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0111 0.0701 0.1574
Echinococcus granulosus activated cdc42 kinase 1 0.0207 0.1634 0.171
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0119 0.0773 0.1747
Echinococcus multilocularis serine:threonine protein kinase 38 0.0046 0.0067 0.0021
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0104 0.0626 0.149
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0466 0.4155 0.4425
Brugia malayi Protein kinase domain containing protein 0.0186 0.1429 0.1388
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.006 0.02 0.0367
Trichomonas vaginalis AGC family protein kinase 0.005 0.0102 0.0131
Echinococcus multilocularis roundabout 2 0.0063 0.0231 0.0198
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.012 0.0784 0.0793
Brugia malayi Furin-like cysteine rich region family protein 0.0998 0.9329 0.9326
Trypanosoma cruzi cdc2-related kinase 3 0.011 0.0684 0.1628
Trypanosoma cruzi casein kinase, putative 0.006 0.0201 0.0478
Echinococcus multilocularis neuroglian 0.0063 0.0231 0.0198
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.0764 0.1812
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0329 0.2818 0.2985
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0104 0.0626 0.0624
Schistosoma mansoni tyrosine kinase 0.0543 0.4902 0.5231
Echinococcus multilocularis casein kinase I delta 0.006 0.0201 0.0166
Loa Loa (eye worm) hypothetical protein 0.0185 0.1417 0.1376
Leishmania major histone deacetylase, putative 0.0064 0.0237 0.0456
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0102 0.0611 0.1358
Echinococcus granulosus titin 0.0057 0.0173 0.0136
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.022 0.0186
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0098 0.057 0.0563
Trypanosoma cruzi histone deacetylase 1, putative 0.0064 0.0237 0.0564
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0115 0.0737 0.0693
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0104 0.0626 0.0582
Echinococcus granulosus hemicentin 1 0.0059 0.0195 0.0159
Schistosoma mansoni tyrosine kinase 0.0138 0.0961 0.0984
Echinococcus granulosus casein kinase i 0.006 0.0201 0.0166
Echinococcus granulosus aurora kinase A 0.0471 0.4203 0.4477
Schistosoma mansoni titin 0.0059 0.0195 0.0159
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0104 0.0626 0.1225
Echinococcus granulosus tyrosine protein kinase Src42A 0.0098 0.057 0.0563
Loa Loa (eye worm) hypothetical protein 0.0078 0.0381 0.0335
Brugia malayi cyclin-dependent kinase 7 homolog 0.0109 0.0675 0.063
Loa Loa (eye worm) hypothetical protein 0.0141 0.0986 0.0943
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0859 0.1953
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0459 0.4084 0.4349
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0116 0.0074
Echinococcus granulosus protein kinase c epsilon type 0.0062 0.022 0.0186
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0217 0.1725 0.1808
Brugia malayi intracellular kinase 0.012 0.0784 0.074
Giardia lamblia Kinase, AGC AKT 0.0108 0.0667 0.1325
Echinococcus granulosus cyclin dependent kinase 9 0.0076 0.0354 0.033
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0119 0.0773 0.0729
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0099 0.0582 0.0576
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0146 0.1035 0.2377
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0044 0.0047 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.1018 0.1046
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0104 0.0626 0.0624
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.1725 0.1808
Brugia malayi probable protein kinase 0.0161 0.1187 0.1145
Brugia malayi Protein kinase domain containing protein 0.0046 0.0067 0.002
Echinococcus granulosus NDR protein kinase 0.0046 0.0067 0.0021
Echinococcus granulosus dual specificity mitogen activated protein 0.0174 0.1314 0.1365
Entamoeba histolytica histone deacetylase, putative 0.0064 0.0237 0.0557
Echinococcus granulosus epidermal growth factor receptor 0.0579 0.5246 0.5601
Giardia lamblia Kinase, CMGC GSK 0.012 0.0784 0.1611
Schistosoma mansoni tyrosine kinase 0.0095 0.0539 0.0529
Schistosoma mansoni protein kinase 0.0161 0.1187 0.1228
Giardia lamblia Kinase, NEK 0.0127 0.0859 0.1796
Schistosoma mansoni tyrosine kinase 0.0054 0.0146 0.0106
Loa Loa (eye worm) histone deacetylase 1 0.0064 0.0237 0.0191
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0141 0.0986 0.1012
Plasmodium falciparum protein kinase 5 0.011 0.0684 0.1533
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0046 0.0067 0.0021
Echinococcus multilocularis tyrosine protein kinase Blk 0.0085 0.0441 0.0424
Onchocerca volvulus 0.0054 0.0146 0.016
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0057 0.0173 0.0127
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0471 0.4203 1
Trichomonas vaginalis CAMK family protein kinase 0.0069 0.029 0.0585
Plasmodium falciparum glycogen synthase kinase 3 0.012 0.0784 0.1772
Loa Loa (eye worm) hypothetical protein 0.0177 0.1342 0.1301
Trypanosoma cruzi histone deacetylase 1, putative 0.0064 0.0237 0.0564
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0083 0.0425 0.0407
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.006 0.02 0.0153
Schistosoma mansoni septate junction protein 0.0059 0.0195 0.0159
Loa Loa (eye worm) hypothetical protein 0.0083 0.0423 0.0377
Brugia malayi Protein kinase domain containing protein 0.0207 0.1634 0.1595
Trichomonas vaginalis CMGC family protein kinase 0.012 0.0784 0.1772
Brugia malayi Tyrosine-protein kinase abl-1 0.0133 0.0909 0.0866
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.006 0.02 0.0164
Toxoplasma gondii AGC kinase 0.0104 0.0626 0.1393
Echinococcus granulosus protein kinase 0.0083 0.0425 0.0407
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0138 0.0961 0.0984
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0186 0.1429 0.1388
Echinococcus multilocularis cyclin dependent kinase 5 0.011 0.0684 0.0686
Loa Loa (eye worm) hypothetical protein 0.019 0.1464 0.1424
Loa Loa (eye worm) hypothetical protein 0.0059 0.0195 0.0148
Giardia lamblia Kinase, NEK 0.0127 0.0859 0.1796
Echinococcus granulosus contactin 0.0063 0.0231 0.0198
Giardia lamblia Kinase, CMGC CLK 0.0146 0.1035 0.2228
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1067 1 1
Echinococcus granulosus Vam6:Vps39 protein 0.0078 0.0381 0.036
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.012 0.0784 0.1772
Echinococcus granulosus roundabout 2 0.0063 0.0231 0.0198
Echinococcus granulosus epidermal growth factor receptor 0.0998 0.9329 1
Giardia lamblia Kinase, CMGC CDK 0.011 0.0684 0.1367
Toxoplasma gondii histone deacetylase HDAC3 0.0064 0.0237 0.0456
Echinococcus granulosus casein kinase I alpha 0.006 0.0201 0.0166
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.014 0.0984 0.0942
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.01 0.0595 0.055
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.006 0.02 0.0178
Loa Loa (eye worm) TK protein kinase 0.0171 0.1278 0.1237
Trichomonas vaginalis CK1 family protein kinase 0.006 0.0201 0.037
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0557 0.5032 0.5
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0046 0.0067 0.0021
Echinococcus multilocularis 0.0083 0.0425 0.0407
Echinococcus granulosus cyclin dependent kinase 5 0.011 0.0684 0.0686
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0046 0.0067 0.0021
Echinococcus granulosus raf serine:threonine protein kinase 0.0051 0.0116 0.0074
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0146 0.1035 0.2463
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0186 0.1429 0.1489
Brugia malayi hypothetical protein 0.0063 0.0235 0.0189
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0579 0.5246 0.5601
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.006 0.02 0.0164
Trypanosoma cruzi casein kinase, putative 0.006 0.0201 0.0478
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0063 0.0231 0.0198
Brugia malayi Hr1 repeat family protein 0.0046 0.0067 0.002
Entamoeba histolytica protein kinase, putative 0.006 0.02 0.0469
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.006 0.02 0.0164
Schistosoma mansoni hypothetical protein 0.0078 0.0381 0.036
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0206 0.1618 0.1692
Entamoeba histolytica p21-activated kinase 0.004 0.0012 0.0023
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0151 0.109 0.2594
Trypanosoma cruzi aurora B kinase, putative 0.0471 0.4203 1
Plasmodium falciparum NIMA related kinase 1 0.0127 0.0859 0.1953
Echinococcus granulosus tyrosine protein kinase Src42A 0.0051 0.0113 0.0071
Schistosoma mansoni cell adhesion molecule 0.0059 0.0195 0.0159
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0459 0.4084 0.4349
Schistosoma mansoni protein kinase 0.0217 0.1729 0.1812
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0059 0.0195 0.0213
Trypanosoma brucei aurora B kinase 0.0471 0.4203 1
Echinococcus multilocularis activin receptor type 0.0436 0.3855 0.4103
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.006 0.02 0.0367
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.2056 0.2164
Echinococcus multilocularis protein kinase c epsilon type 0.0062 0.022 0.0186
Loa Loa (eye worm) TK protein kinase 0.0085 0.0441 0.0396
Trichomonas vaginalis AGC family protein kinase 0.005 0.0102 0.0131
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0206 0.1618 0.3849
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0128 0.0087
Loa Loa (eye worm) AGC/PKA protein kinase 0.0104 0.0626 0.0582
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0064 0.0237 0.0456
Loa Loa (eye worm) hypothetical protein 0.0122 0.0802 0.0759
Plasmodium falciparum histone deacetylase 1 0.0064 0.0237 0.0456
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0146 0.1035 0.2377
Brugia malayi cell division control protein 2 homolog 0.011 0.0684 0.064
Onchocerca volvulus 0.0054 0.0146 0.016
Trichomonas vaginalis histone deacetylase, putative 0.0064 0.0237 0.0456
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.012 0.0784 0.0793
Giardia lamblia Kinase, CMGC CDK 0.011 0.0684 0.1367
Schistosoma mansoni tyrosine kinase 0.0455 0.4048 0.431
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0078 0.0381 0.036
Trichomonas vaginalis CAMK family protein kinase 0.0119 0.0773 0.1747
Loa Loa (eye worm) hypothetical protein 0.0125 0.0834 0.079
Trichomonas vaginalis CK1 family protein kinase 0.006 0.0201 0.037
Brugia malayi bone morphogenetic protein type 1 receptor 0.011 0.0686 0.0641
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.01 0.0591 0.0586
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0146 0.1035 0.2463
Loa Loa (eye worm) hypothetical protein 0.006 0.02 0.0153
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.006 0.02 0.0153
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0206 0.1618 0.3779
Brugia malayi Protein kinase domain containing protein 0.0206 0.1618 0.1578
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0085 0.0441 0.0424
Entamoeba histolytica protein kinase, putative 0.0471 0.4203 1
Echinococcus multilocularis death associated protein kinase 1 0.0865 0.803 0.86
Loa Loa (eye worm) hypothetical protein 0.0078 0.0381 0.0335
Brugia malayi hypothetical protein 0.0217 0.1725 0.1686
Schistosoma mansoni tyrosine kinase 0.0098 0.057 0.0563
Schistosoma mansoni neuroglian 0.0063 0.0231 0.0198
Loa Loa (eye worm) AGC/NDR protein kinase 0.0046 0.0067 0.002
Schistosoma mansoni serine/threonine protein kinase 0.026 0.2149 0.2264
Trichomonas vaginalis STE family protein kinase 0.0174 0.1314 0.3048
Echinococcus granulosus peroxidasin 0.006 0.0199 0.0163
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0146 0.1035 0.2463
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0145 0.1025 0.1053
Echinococcus multilocularis histone deacetylase 3 0.0064 0.0237 0.0204
Brugia malayi hypothetical protein 0.0122 0.0802 0.0759
Trypanosoma cruzi casein kinase, putative 0.006 0.0201 0.0478
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0175 0.1317 0.1369
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0051 0.0113 0.0071
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.01 0.0589 0.0545
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0115 0.0735 0.0741
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0684 0.1533
Trichomonas vaginalis histone deacetylase, putative 0.0064 0.0237 0.0456
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0274 0.0646
Schistosoma mansoni protein kinase C mu 0.01 0.0589 0.0584
Echinococcus multilocularis cyclin dependent kinase 0.011 0.0684 0.0686
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0063 0.0231 0.0198
Echinococcus multilocularis tyrosine protein kinase otk 0.0059 0.0195 0.0159
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0195 0.0148
Echinococcus multilocularis roundabout 2 0.0063 0.0231 0.0198
Onchocerca volvulus 0.0078 0.0381 0.0417
Brugia malayi hypothetical protein 0.0078 0.0381 0.0335
Echinococcus multilocularis protein kinase c iota type 0.0062 0.022 0.0186
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0146 0.0099
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0098 0.057 0.0563
Leishmania major protein kinase, putative 0.0471 0.4203 1
Treponema pallidum licC protein (licC) 0.0102 0.0611 0.5
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.006 0.02 0.0178
Echinococcus multilocularis hemicentin 1 0.0059 0.0195 0.0159
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0146 0.0099
Brugia malayi Tyrosine-protein kinase abl-1 0.015 0.1073 0.1031
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0098 0.057 0.0563
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0684 0.0686
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0133 0.0914 0.0934
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.006 0.0201 0.0155
Giardia lamblia Kinase, NEK 0.0127 0.0859 0.1796
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0164 0.0383
Loa Loa (eye worm) hypothetical protein 0.0122 0.0802 0.0759
Onchocerca volvulus Serine\/threonine kinase homolog 0.0119 0.0773 0.0846
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0127 0.0859 0.1796
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0626 0.0624
Giardia lamblia Kinase, CMGC GSK 0.012 0.0784 0.1611
Brugia malayi serine/threonine kinase 12 0.0471 0.4203 0.4175
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.012 0.0784 0.1864
Brugia malayi Protein kinase domain containing protein 0.0054 0.0146 0.0099
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.006 0.02 0.0164
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0085 0.0441 0.0424
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0211 0.1667 0.1627
Plasmodium falciparum calcium-dependent protein kinase 2 0.006 0.02 0.0367
Trypanosoma cruzi casein kinase, delta isoform, putative 0.006 0.0201 0.0478
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0195 0.0148
Echinococcus multilocularis twitchin 0.0053 0.0137 0.0097
Schistosoma mansoni histone deacetylase 0.0064 0.0237 0.0204
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0128 0.0087
Schistosoma mansoni septate junction protein 0.0059 0.0195 0.0159
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0194 0.1509 0.1469
Onchocerca volvulus 0.0057 0.0173 0.019
Echinococcus granulosus TGF beta receptor type 1 0.0095 0.0543 0.0534
Entamoeba histolytica protein kinase domain containing protein 0.0206 0.1618 0.3845
Onchocerca volvulus 0.0144 0.1016 0.1112
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0059 0.0195 0.0148
Echinococcus multilocularis TGF beta receptor type 1 0.0095 0.0543 0.0534
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0067 0.0047
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0094 0.0536 0.0527
Echinococcus multilocularis Immunoglobulin 0.0118 0.0766 0.0774
Schistosoma mansoni tyrosine kinase 0.0102 0.0606 0.0603
Entamoeba histolytica PH domain containing protein kinase, putative 0.0107 0.0661 0.1566
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0083 0.0425 0.0407
Schistosoma mansoni protein kinase 0.0056 0.0164 0.0126
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.114 0.1178
Brugia malayi cyclin-dependent kinase 9 0.0067 0.0274 0.0228
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.01 0.0591 0.0547
Brugia malayi Fibronectin type III domain containing protein 0.0122 0.0802 0.0759
Brugia malayi P38 map kinase family protein 2 0.0151 0.109 0.1048
Loa Loa (eye worm) hypothetical protein 0.0172 0.1291 0.1249
Loa Loa (eye worm) hypothetical protein 0.0177 0.1342 0.1301
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0118 0.0766 0.0774
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0174 0.1314 0.1273
Loa Loa (eye worm) hypothetical protein 0.0066 0.0263 0.0216
Trypanosoma brucei cdc2-related kinase 1 0.011 0.0684 0.1533
Brugia malayi histone deacetylase 1 (HD1) 0.0064 0.0237 0.0191
Loa Loa (eye worm) hypothetical protein 0.0063 0.0235 0.0189
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0595 0.059
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.011 0.0684 0.064
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.011 0.0684 0.1533
Echinococcus granulosus histone deacetylase 3 0.0064 0.0237 0.0204
Trichomonas vaginalis AGC family protein kinase 0.005 0.0102 0.0131
Entamoeba histolytica casein kinase 1, putative 0.006 0.0201 0.0472
Schistosoma mansoni tyrosine kinase 0.0455 0.4048 0.431
Loa Loa (eye worm) hypothetical protein 0.0059 0.0195 0.0148
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0104 0.0626 0.0624
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0186 0.1429 0.1564
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0104 0.0626 0.0624
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0067 0.0275 0.0245
Echinococcus granulosus Immunoglobulin 0.0118 0.0766 0.0774
Loa Loa (eye worm) TK/ALK protein kinase 0.0568 0.5139 0.5116
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.011 0.0684 0.0686
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0067 0.0021
Schistosoma mansoni tyrosine kinase 0.0052 0.0121 0.0079
Plasmodium falciparum protein serine/threonine kinase-1 0.0146 0.1035 0.2377
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0962 0.8972 0.8967
Echinococcus multilocularis protein tyrosine kinase 0.0297 0.2511 0.2654
Echinococcus granulosus tyrosine protein kinase Fyn 0.0098 0.057 0.0563
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0206 0.1618 0.1578
Loa Loa (eye worm) hypothetical protein 0.0122 0.0802 0.0759
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0138 0.0961 0.0984
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0471 0.4203 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0235 0.0189
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0046 0.0067 0.002
Brugia malayi Immunoglobulin I-set domain containing protein 0.0062 0.0225 0.0179
Echinococcus granulosus titin 0.0057 0.0173 0.0136
Echinococcus multilocularis activated cdc42 kinase 1 0.0207 0.1634 0.171
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0557 0.5032 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0471 0.4203 0.4477
Brugia malayi Stress-activated protein kinase jnk-1 0.026 0.2149 0.2111
Giardia lamblia Kinase, PLK 0.0119 0.0773 0.1586
Trichomonas vaginalis histone deacetylase, putative 0.0064 0.0237 0.0456
Toxoplasma gondii AGC kinase 0.0104 0.0626 0.1393
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0217 0.1729 0.1812
Echinococcus multilocularis peroxidasin 0.006 0.0199 0.0163
Trichomonas vaginalis AGC family protein kinase 0.005 0.0102 0.0131
Trichomonas vaginalis AGC family protein kinase 0.005 0.0102 0.0131
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0046 0.0067 0.002
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0098 0.057 0.0563
Loa Loa (eye worm) TK/EGFR protein kinase 0.0998 0.9329 0.9326
Entamoeba histolytica protein kinase, putative 0.0046 0.0067 0.0153
Entamoeba histolytica protein kinase, putative 0.0046 0.0067 0.0153
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.01 0.0591 0.0586
Loa Loa (eye worm) hypothetical protein 0.0059 0.0195 0.0148
Brugia malayi Protein kinase domain containing protein 0.0054 0.0146 0.0099
Loa Loa (eye worm) AGC/AKT protein kinase 0.005 0.0102 0.0055
Loa Loa (eye worm) hypothetical protein 0.0144 0.1016 0.0974
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.022 0.0186
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0151 0.109 0.251
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0186 0.1429 0.1388
Echinococcus granulosus protein kinase shaggy 0.012 0.0784 0.0793
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0062 0.0225 0.0179
Brugia malayi histone deacetylase 3 (HD3) 0.0064 0.0237 0.0191
Entamoeba histolytica protein kinase, putative 0.005 0.0102 0.0235
Brugia malayi Protein kinase domain containing protein 0.0054 0.0146 0.0099
Plasmodium vivax protein kinase Crk2 0.011 0.0684 0.1367
Echinococcus multilocularis casein kinase I alpha 0.006 0.0201 0.0166
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0098 0.057 0.0563
Plasmodium vivax casein kinase 1, putative 0.006 0.0201 0.0182
Schistosoma mansoni cell adhesion molecule 0.0063 0.0231 0.0198
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0195 0.0148
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0063 0.0231 0.0198
Trypanosoma brucei cdc2-related kinase 3 0.011 0.0684 0.1533
Echinococcus granulosus tyrosine kinase 0.0054 0.0146 0.0106
Schistosoma mansoni protein kinase 0.0174 0.1314 0.1365
Onchocerca volvulus 0.0083 0.0423 0.0463
Trichomonas vaginalis CK1 family protein kinase 0.006 0.0201 0.037
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0201 0.0166
Brugia malayi serine/threonine-protein kinase PAK 7 0.0211 0.1667 0.1627
Entamoeba histolytica serine/threonine protein kinase, putative 0.0119 0.0773 0.1834
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0343
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0098 0.057 0.0563
Schistosoma mansoni protein kinase 0.0175 0.1317 0.1369
Echinococcus granulosus dual specificity 0.0206 0.1618 0.1692
Plasmodium falciparum casein kinase 1 0.006 0.0201 0.037
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0115 0.0737 0.0693
Loa Loa (eye worm) TK/ABL protein kinase 0.0269 0.2234 0.2197
Onchocerca volvulus 0.012 0.0784 0.0858
Brugia malayi serine/threonine-protein kinase 6 0.0471 0.4203 0.4175
Schistosoma mansoni vam6/vps39 related 0.0078 0.0381 0.036
Schistosoma mansoni kinase 0.0067 0.0274 0.0245
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0082 0.0412 0.0393
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0146 0.0099
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0154 0.1114 0.1072
Brugia malayi hypothetical protein 0.0054 0.0146 0.0099
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0084 0.0436 0.0391
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.01 0.0591 0.0586
Echinococcus granulosus tyrosine protein kinase Blk 0.0085 0.0441 0.0424
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0147 0.0239
Brugia malayi Protein kinase domain containing protein 0.0081 0.0411 0.0365
Trichomonas vaginalis CAMK family protein kinase 0.0119 0.0773 0.1747
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0098 0.057 0.0563
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.011 0.0684 0.064
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0054 0.0146 0.034
Plasmodium falciparum calcium-dependent protein kinase 1 0.006 0.02 0.0367
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0098 0.057 0.0563
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0064 0.0237 0.0456
Echinococcus granulosus c-Jun N-terminal kinases 0.026 0.2149 0.2264
Echinococcus granulosus cyclin dependent kinase 0.011 0.0684 0.0686
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0063 0.0229 0.0182
Entamoeba histolytica cell division protein kinase 2, putative 0.011 0.0684 0.1622
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0146 0.0099
Echinococcus granulosus fibroblast growth factor receptor 4 0.0138 0.0961 0.0984
Entamoeba histolytica protein kinase domain containing protein 0.012 0.0784 0.1859
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.011 0.0684 0.1533
Brugia malayi Immunoglobulin I-set domain containing protein 0.0063 0.0231 0.0185
Loa Loa (eye worm) hypothetical protein 0.0063 0.0231 0.0185
Leishmania major protein kinase A catalytic subunit isoform 2 0.0104 0.0626 0.1393
Echinococcus granulosus neuroglian 0.0063 0.0231 0.0198
Trichomonas vaginalis CAMK family protein kinase 0.0119 0.0773 0.1747
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0684 0.0686
Brugia malayi Immunoglobulin I-set domain containing protein 0.0063 0.0231 0.0185
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0084 0.0432 0.0387
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0081 0.0411 0.0391
Echinococcus granulosus casein kinase I delta 0.006 0.0201 0.0166
Loa Loa (eye worm) hypothetical protein 0.0144 0.1016 0.0974
Brugia malayi Immunoglobulin I-set domain containing protein 0.0171 0.1278 0.1237
Echinococcus granulosus casein kinase I alpha 0.006 0.0201 0.0166
Echinococcus multilocularis titin 0.0057 0.0173 0.0136
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.006 0.0201 0.0155
Toxoplasma gondii histone deacetylase HDAC2 0.0064 0.0237 0.0456
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0046 0.0067 0.0021
Echinococcus multilocularis lachesin 0.0059 0.0195 0.0159
Brugia malayi casein kinase I 0.006 0.0201 0.0155
Brugia malayi Protein kinase domain containing protein 0.011 0.0684 0.064
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0115 0.0735 0.0741
Brugia malayi Protein kinase domain containing protein 0.0054 0.0146 0.0099
Brugia malayi Immunoglobulin I-set domain containing protein 0.0063 0.0231 0.0185
Echinococcus granulosus hypothetical protein 0.0125 0.0834 0.0848
Echinococcus granulosus tyrosine kinase 0.0085 0.0441 0.0424
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0274 0.0245
Echinococcus multilocularis histone deacetylase 1 0.0064 0.0237 0.0204
Trichomonas vaginalis STE family protein kinase 0.0174 0.1314 0.3048
Echinococcus granulosus roundabout 2 0.0063 0.0231 0.0198
Echinococcus granulosus neuroglian 0.0151 0.1083 0.1116
Plasmodium falciparum calcium-dependent protein kinase 5 0.006 0.02 0.0367
Onchocerca volvulus 0.0063 0.0235 0.0258
Brugia malayi Protein kinase domain containing protein 0.0052 0.0128 0.0081
Echinococcus multilocularis mitogen activated protein kinase 14 0.0151 0.109 0.1124
Toxoplasma gondii casein kinase I 0.006 0.0201 0.037
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0063 0.0231 0.0198
Echinococcus granulosus tyrosine protein kinase Lyn 0.0118 0.0771 0.078
Loa Loa (eye worm) hypothetical protein 0.0064 0.0237 0.0191
Echinococcus multilocularis epidermal growth factor receptor 0.0579 0.5246 0.5601

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 2.5 uM Displacement of FITC-AHx-KALETLRRVGDGVQRNHETAF-NH2 from human MCl1 (172 to 327) expressed in Escherichia coli BL21 (DE3) after 1 hr by fluorescence polarization anisotropy assay ChEMBL. 23244564

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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