Detailed information for compound 1761320

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 738.945 | Formula: C40H66O12
  • H donors: 6 H acceptors: 8 LogP: 3.99 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 3
  • SMILES: CC(=O)O[C@@H]1CC[C@]2(C(C1(C)C)C[C@H]([C@@]1(C2CC[C@@]23[C@]1(CC[C@H]3[C@H](C[C@@H]([C@H](C(O)(C)C)O)O)C)C2)C)OC1OC(COC(=O)C)C(C(C1O)O)O)C
  • InChi: 1S/C40H66O12/c1-20(16-24(43)33(47)36(6,7)48)23-10-15-40-19-39(23,40)14-11-26-37(8)13-12-28(50-22(3)42)35(4,5)27(37)17-29(38(26,40)9)52-34-32(46)31(45)30(44)25(51-34)18-49-21(2)41/h20,23-34,43-48H,10-19H2,1-9H3/t20-,23-,24-,25?,26?,27?,28+,29+,30?,31?,32?,33+,34?,37+,38-,39+,40+/m0/s1
  • InChiKey: LWBFDADHSVYUPS-MGNZBQQGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0236 0.1271 0.4607
Entamoeba histolytica hypothetical protein 0.0236 0.1271 0.3859
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0027 0.0209
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0028 0.0059 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0092 0.033
Trichomonas vaginalis conserved hypothetical protein 0.0236 0.1271 0.4607
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Schistosoma mansoni tensin-related 0.0343 0.1898 0.1898
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0179 0.018
Onchocerca volvulus 0.004 0.0129 0.0359
Loa Loa (eye worm) glutamate receptor 1 0.1128 0.6481 0.6518
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0012 0.0041
Schistosoma mansoni ap endonuclease 0.0023 0.0027 0.0027
Brugia malayi STAT protein, DNA binding domain containing protein 0.0343 0.1898 0.1908
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0321 0.2524
Loa Loa (eye worm) TK/ALK protein kinase 0.0236 0.1271 0.1278
Brugia malayi bone morphogenetic protein type 1 receptor 0.0236 0.1271 0.1278
Leishmania major cathepsin L-like protease 0.0077 0.0344 0.2705
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0268 0.211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0092 0.033
Brugia malayi metabotropic glutamate receptor type 2 0.013 0.0654 0.0658
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0236 0.1271 0.3859
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0051 0.0183
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0236 0.1271 1
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0322 0.0324
Loa Loa (eye worm) TK protein kinase 0.0236 0.1271 0.1278
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0236 0.1271 0.3859
Echinococcus granulosus tyrosine protein kinase 0.0236 0.1271 0.1278
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0012 0.0012
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0028 0.0059 0.0059
Brugia malayi Receptor family ligand binding region containing protein 0.013 0.0654 0.0658
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0236 0.1271 0.3859
Echinococcus granulosus fibroblast growth factor receptor 4 0.0236 0.1271 0.1278
Brugia malayi beta-lactamase family protein 0.0073 0.0321 0.0323
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Echinococcus granulosus peptide allatostatin:somatostatin 0.004 0.0129 0.013
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0028 0.0059 0.0059
Onchocerca volvulus 0.0152 0.0782 0.236
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0236 0.1271 1
Loa Loa (eye worm) SRC-1 0.0579 0.3275 0.3293
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0012 0.0041
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Brugia malayi Variant SH3 domain containing protein 0.0343 0.1898 0.1908
Loa Loa (eye worm) TK/CSK protein kinase 0.0236 0.1271 0.1278
Onchocerca volvulus 0.0579 0.3275 1
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Entamoeba histolytica hypothetical protein 0.0236 0.1271 0.3859
Echinococcus granulosus neuropeptide receptor A26 0.0596 0.3374 0.3393
Loa Loa (eye worm) TK/FER protein kinase 0.0579 0.3275 0.3293
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0028 0.0059 0.0059
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0236 0.1271 0.1278
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Schistosoma mansoni metabotropic glutamate receptor 0.013 0.0654 0.0654
Schistosoma mansoni nck2/grb4 0.0343 0.1898 0.1898
Brugia malayi metabotropic GABA-B receptor subtype 2 0.013 0.0654 0.0658
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0236 0.1271 0.4607
Echinococcus multilocularis protein kinase 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Brugia malayi SH2 domain containing protein 0.0343 0.1898 0.1908
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0058 0.0234 0.0235
Loa Loa (eye worm) TK/RYK protein kinase 0.0236 0.1271 0.1278
Entamoeba histolytica serine/threonine kinase, putative 0.0236 0.1271 0.3859
Loa Loa (eye worm) hypothetical protein 0.0037 0.0107 0.0108
Entamoeba histolytica hypothetical protein 0.0236 0.1271 0.3859
Loa Loa (eye worm) RGC/RGC protein kinase 0.0366 0.2031 0.2043
Brugia malayi Serotonin/octopamine receptor family protein 7 0.004 0.0129 0.013
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0343 0.1898 0.1898
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0027 0.0136
Brugia malayi Dopamine receptor protein 1 0.004 0.0129 0.013
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0343 0.1898 0.1908
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0321 0.0321
Brugia malayi plexin A 0.0104 0.0499 0.0501
Onchocerca volvulus 0.0028 0.0059 0.0144
Loa Loa (eye worm) hypothetical protein 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0236 0.1271 0.1278
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.016 0.1257
Brugia malayi Immunoglobulin I-set domain containing protein 0.0251 0.1359 0.1367
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Brugia malayi excitatory GABA receptor EXP-1A 0.0028 0.0059 0.0059
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.016 0.0161
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0175 0.0175
Echinococcus granulosus plexin a4 0.0104 0.0499 0.0501
Echinococcus multilocularis tyrosine protein kinase Srms 0.0579 0.3275 0.3293
Schistosoma mansoni protein kinase 0.0236 0.1271 0.1271
Echinococcus granulosus ferritin 0.0018 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0344 0.2705
Loa Loa (eye worm) hypothetical protein 0.1721 0.9944 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0027 0.0209
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0456 0.0459
Loa Loa (eye worm) CXXC zinc finger family protein 0.0119 0.0589 0.0592
Echinococcus multilocularis cysteine protease 0.002 0.0012 0.0012
Brugia malayi hypothetical protein 0.013 0.0654 0.0658
Echinococcus granulosus insulin receptor 0.0236 0.1271 0.1278
Echinococcus multilocularis epidermal growth factor receptor 0.0236 0.1271 0.1278
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0344 0.2705
Loa Loa (eye worm) hypothetical protein 0.013 0.0654 0.0658
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Echinococcus multilocularis L aminoadipate semialdehyde 0.01 0.048 0.0483
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0027 0.0045
Echinococcus granulosus fmrfamide receptor 0.004 0.0129 0.013
Loa Loa (eye worm) serotonin transporter b 0.0343 0.1896 0.1906
Onchocerca volvulus 0.049 0.2759 0.8418
Echinococcus granulosus raf serine:threonine protein kinase 0.0236 0.1271 0.1278
Loa Loa (eye worm) TK/FER protein kinase 0.0579 0.3275 0.3293
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0027 0.0027
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0579 0.3275 0.3293
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Schistosoma mansoni glutamate receptor kainate 0.0686 0.3902 0.3902
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0236 0.1271 1
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Loa Loa (eye worm) jmjC domain-containing protein 0.0075 0.0331 0.0333
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.004 0.0129 0.0359
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Plasmodium falciparum transporter, putative 0.0058 0.0234 0.1839
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0121 0.0436
Loa Loa (eye worm) hypothetical protein 0.01 0.048 0.0483
Echinococcus multilocularis G-protein coupled receptor, putative 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Schistosoma mansoni protein tyrosine kinase 0.0236 0.1271 0.1271
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0343 0.1898 0.1898
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0343 0.1898 0.1908
Schistosoma mansoni sodium/chloride dependent transporter 0.0058 0.0234 0.0234
Echinococcus granulosus kinase suppressor of Ras 1 0.0236 0.1271 0.1278
Echinococcus multilocularis neuropeptide FF receptor 2 0.004 0.0129 0.013
Echinococcus granulosus X box binding protein 1 0.0348 0.1926 0.1937
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0012 0.0041
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0321 0.1222
Entamoeba histolytica hypothetical protein, conserved 0.0236 0.1271 0.3859
Loa Loa (eye worm) hypothetical protein 0.0058 0.0234 0.0235
Brugia malayi tRNA modification GTPase TrmE family protein 0.0343 0.1898 0.1908
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0028 0.0059 0.0463
Brugia malayi hypothetical protein 0.004 0.0129 0.013
Echinococcus granulosus glycine receptor subunit alpha 1 0.0028 0.0059 0.0059
Echinococcus multilocularis tyrosine protein kinase 0.0236 0.1271 0.1278
Schistosoma mansoni tyrosine kinase 0.0366 0.2031 0.2031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0092 0.033
Loa Loa (eye worm) hypothetical protein 0.0442 0.2474 0.2488
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0236 0.1271 0.3859
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Echinococcus multilocularis activated cdc42 kinase 1 0.0236 0.1271 0.1278
Onchocerca volvulus 0.004 0.0129 0.0359
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Onchocerca volvulus 0.0088 0.0405 0.1204
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Loa Loa (eye worm) hypothetical protein 0.0236 0.1271 0.1278
Plasmodium vivax SET domain protein, putative 0.0064 0.0268 0.211
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0322 0.0322
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0058 0.0234 0.0235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0092 0.033
Mycobacterium tuberculosis Conserved protein 0.0073 0.0321 0.1222
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0051 0.0183
Loa Loa (eye worm) hypothetical protein 0.013 0.0654 0.0658
Loa Loa (eye worm) neuropeptide F receptor 0.004 0.0129 0.013
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0236 0.1271 0.1278
Loa Loa (eye worm) TK/FER protein kinase 0.0236 0.1271 0.1278
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0027 0.0099
Brugia malayi hypothetical protein 0.004 0.0129 0.013
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0058 0.0234 0.0235
Plasmodium vivax tyrosine kinase-like protein, putative 0.0236 0.1271 1
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0236 0.1271 0.1278
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.004 0.0129 0.0129
Echinococcus multilocularis serotonin transporter 0.0343 0.1896 0.1906
Echinococcus granulosus semaphorin 1A 0.0037 0.0107 0.0108
Trypanosoma brucei Pseudokinase, putative 0.0236 0.1271 1
Echinococcus multilocularis signal transduction protein lnk realted 0.0343 0.1898 0.1908
Onchocerca volvulus 0.0073 0.0321 0.0947
Echinococcus multilocularis heat shock protein 70 0.0236 0.1271 0.1278
Brugia malayi Cathepsin L-like precursor 0.002 0.0012 0.0012
Entamoeba histolytica hypothetical protein 0.0236 0.1272 0.3861
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0012 0.0012
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0027 0.0209
Echinococcus granulosus natriuretic peptide receptor 1 0.0236 0.1271 0.1278
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0137 0.0137
Trichomonas vaginalis esterase, putative 0.0073 0.0321 0.1161
Echinococcus granulosus orexin receptor type 2 0.004 0.0129 0.013
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0597 0.06
Brugia malayi SH2 domain containing protein 0.0343 0.1898 0.1908
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.004 0.0129 0.013
Echinococcus granulosus glycine receptor subunit alpha 1 0.0028 0.0059 0.0059
Toxoplasma gondii ABC1 family protein 0.0073 0.0321 0.2524
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0051 0.0183
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Brugia malayi SH2 domain containing protein 0.0343 0.1898 0.1908
Loa Loa (eye worm) TK/FER protein kinase 0.0579 0.3275 0.3293
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0343 0.1898 0.5779
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.0059 0.0059
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0058 0.0234 0.0234
Loa Loa (eye worm) TK/FER protein kinase 0.0236 0.1271 0.1278
Loa Loa (eye worm) hypothetical protein 0.0058 0.0234 0.0235
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0343 0.1898 0.1908
Loa Loa (eye worm) hypothetical protein 0.0442 0.2474 0.2488
Trichomonas vaginalis set domain proteins, putative 0.049 0.2759 1
Loa Loa (eye worm) hypothetical protein 0.0236 0.1271 0.1278
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0343 0.1898 0.1908
Schistosoma mansoni protein kinase 0.0236 0.1271 0.1271
Echinococcus granulosus nmda type glutamate receptor 0.1168 0.6715 0.6753
Schistosoma mansoni microtubule-associated protein tau 0.0766 0.4367 0.4367
Entamoeba histolytica hypothetical protein 0.0236 0.1271 0.3859
Echinococcus multilocularis sodium and chloride dependent glycine 0.0058 0.0234 0.0235
Loa Loa (eye worm) hypothetical protein 0.0088 0.0405 0.0407
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0579 0.3275 0.3293
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0321 1
Trichomonas vaginalis conserved hypothetical protein 0.0236 0.1271 0.4607
Schistosoma mansoni ephrin receptor 0.0236 0.1271 0.1271
Schistosoma mansoni cpg binding protein 0.0126 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Echinococcus multilocularis tensin 0.0343 0.1898 0.1908
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0058 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0134 0.0679 0.0683
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0343 0.1898 0.1908
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0236 0.1271 0.3859
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0254 0.1377 0.1385
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0579 0.3275 0.3293
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Onchocerca volvulus 0.004 0.0129 0.0359
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0343 0.1898 0.1908
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0331 0.0331
Echinococcus multilocularis tyrosine protein kinase csk 0.0236 0.1271 0.1278
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.016 0.0161
Echinococcus multilocularis neuropeptides capa receptor 0.004 0.0129 0.013
Schistosoma mansoni neuropeptide F-like receptor 0.004 0.0129 0.0129
Schistosoma mansoni tyrosine kinase 0.0579 0.3275 0.3275
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0236 0.1271 0.1278
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0579 0.3275 0.3293
Loa Loa (eye worm) TK/ABL protein kinase 0.0579 0.3275 0.3293
Loa Loa (eye worm) glutamate receptor 2 0.0686 0.3902 0.3924
Echinococcus multilocularis semaphorin 5B 0.0037 0.0107 0.0108
Echinococcus granulosus g-protein coupled receptor 0.004 0.0129 0.013
Loa Loa (eye worm) RGC/RGC protein kinase 0.0366 0.2031 0.2043
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus granulosus tm gpcr rhodopsin 0.004 0.0129 0.013
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Entamoeba histolytica hypothetical protein 0.0236 0.1271 0.3859
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0059 0.0463
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0129
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0816 0.4662 0.4688
Brugia malayi CXXC zinc finger family protein 0.0119 0.0589 0.0592
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0268 0.027
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0028 0.0059 0.0059
Entamoeba histolytica protein kinase, putative 0.0343 0.1898 0.5779
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0268 0.027
Brugia malayi Muscleblind-like protein 0.1721 0.9944 1
Schistosoma mansoni nAChR subunit 0.0028 0.0059 0.0059
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0068 0.0292 0.0293
Loa Loa (eye worm) hypothetical protein 0.0073 0.0321 0.0323
Echinococcus granulosus serotonin receptor 0.004 0.0129 0.013
Echinococcus multilocularis SH2 motif 0.0343 0.1898 0.1908
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Onchocerca volvulus 0.004 0.0129 0.0359
Trichomonas vaginalis conserved hypothetical protein 0.0236 0.1271 0.4607
Loa Loa (eye worm) TK protein kinase 0.0236 0.1271 0.1278
Brugia malayi RNA binding protein 0.0073 0.0322 0.0324
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0321 0.1161
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0028 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Echinococcus multilocularis neuropeptides capa receptor 0.004 0.0129 0.013
Schistosoma mansoni ferritin 0.0018 0.0001 0.0001
Onchocerca volvulus 0.004 0.0129 0.0359
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0343 0.1898 0.1908
Schistosoma mansoni tyrosine kinase 0.0366 0.2031 0.2031
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0236 0.1271 0.1278
Echinococcus multilocularis fmrfamide receptor 0.004 0.0129 0.013
Entamoeba histolytica serine/threonine kinase, putative 0.0236 0.1271 0.3859
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Echinococcus multilocularis X box binding protein 1 0.0348 0.1926 0.1937
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0012 0.0012
Loa Loa (eye worm) sema domain-containing protein 0.0037 0.0107 0.0108
Echinococcus multilocularis tyrosine protein kinase Blk 0.0579 0.3275 0.3293
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0059 0.0059
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0058 0.0234 0.0235
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0236 0.1271 0.3859
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.004 0.0129 0.013
Echinococcus granulosus 7TM GPCR rhodopsin 0.004 0.0129 0.013
Echinococcus multilocularis tumor protein p63 0.0329 0.1814 0.1824
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0343 0.1898 0.1908
Echinococcus granulosus tar DNA binding protein 0.0073 0.0322 0.0324
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0027 0.0094
Onchocerca volvulus 0.01 0.048 0.1435
Loa Loa (eye worm) neuropeptide F receptor 0.004 0.0129 0.013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0012 0.0041
Onchocerca volvulus 0.0236 0.1271 0.3859
Echinococcus granulosus glutamate receptor subunit protein glur 0.0696 0.3957 0.3979
Schistosoma mansoni semaphorin 5-related 0.0037 0.0107 0.0107
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.0059 0.0059
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.004 0.0129 0.0129
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0012 0.0041
Brugia malayi SH2 domain containing protein 0.0343 0.1898 0.1908
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0037 0.0133
Brugia malayi jmjC domain containing protein 0.0068 0.0292 0.0293
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0236 0.1271 0.3859
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Schistosoma mansoni jumonji domain containing protein 0.0068 0.0292 0.0292
Echinococcus multilocularis SH2 motif 0.0343 0.1898 0.1908
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0321 0.1161
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0254 0.1377 0.1385
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Brugia malayi ORL1-like opioid receptor 0.004 0.0129 0.013
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.004 0.0129 0.013
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0236 0.1271 0.1271
Schistosoma mansoni sodium/chloride dependent transporter 0.0343 0.1896 0.1896
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Trypanosoma cruzi cruzipain precursor, putative 0.0077 0.0344 0.2705
Loa Loa (eye worm) norepinephrine transporter 0.0343 0.1896 0.1906
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0179 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0012 0.0041
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0028 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0129
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0129 0.013
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0236 0.1271 0.1278
Echinococcus granulosus biogenic amine 5HT receptor 0.004 0.0129 0.013
Schistosoma mansoni tyrosine kinase 0.0579 0.3275 0.3275
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0037 0.0133
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0236 0.1271 0.3859
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0027 0.0094
Trichomonas vaginalis TK family protein kinase 0.0236 0.1271 0.4607
Echinococcus granulosus tyrosine protein kinase Blk 0.0579 0.3275 0.3293
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0255 0.138 0.138
Brugia malayi ephrin receptor 1 precursor 0.0236 0.1271 0.1278
Schistosoma mansoni intermediate filament proteins 0.0033 0.0084 0.0084
Schistosoma mansoni tyrosine protein kinase 0.0236 0.1271 0.1271
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0816 0.4662 0.4688
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0027 0.0209
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0236 0.1271 0.1278
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0012 0.0012
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0012 0.0041
Echinococcus granulosus cathepsin l1 0.002 0.0012 0.0012
Echinococcus multilocularis g protein coupled receptor 0.004 0.0129 0.013
Brugia malayi Raf kinase 0.0236 0.1271 0.1278
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0322 0.0322
Echinococcus multilocularis plexin a4 0.0104 0.0499 0.0501
Loa Loa (eye worm) hypothetical protein 0.0236 0.1271 0.1278
Loa Loa (eye worm) hypothetical protein 0.0343 0.1896 0.1906
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Echinococcus granulosus G protein coupled receptor 139 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0343 0.1896 0.1906
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.1258 0.7242 0.7283
Schistosoma mansoni protein kinase 0.0236 0.1271 0.1271
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Schistosoma mansoni sodium/chloride dependent transporter 0.0058 0.0234 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0236 0.1271 0.4607
Brugia malayi SH2 domain containing protein 0.0343 0.1898 0.1908
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.024 0.0241
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.004 0.0129 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0092 0.033
Echinococcus granulosus nAChR subunit 0.0028 0.0059 0.0059
Echinococcus granulosus glycine receptor subunit beta 0.0028 0.0059 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus multilocularis protein KINase family member (kin 25) 0.0236 0.1271 0.1278
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0028 0.0059 0.0059
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0028 0.0059 0.0059
Brugia malayi hypothetical protein 0.0579 0.3275 0.3293
Brugia malayi Plexin repeat family protein 0.0088 0.0405 0.0407
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Loa Loa (eye worm) hypothetical protein 0.013 0.0654 0.0658
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.004 0.0129 0.013
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0084 0.0085
Echinococcus granulosus activated cdc42 kinase 1 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0236 0.1271 0.1271
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0456 0.0459
Loa Loa (eye worm) TK protein kinase 0.0579 0.3275 0.3293
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0028 0.0059 0.0059
Brugia malayi hypothetical protein 0.004 0.0129 0.013
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0321 0.2524
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0236 0.1271 0.1278
Echinococcus granulosus tyrosine protein kinase shark 0.0579 0.3275 0.3293
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0816 0.4662 0.4688
Onchocerca volvulus 0.013 0.0654 0.1968
Loa Loa (eye worm) hypothetical protein 0.0073 0.0321 0.0323
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0028 0.0059 0.0059
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0028 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0012 0.0041
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0236 0.1271 0.1271
Echinococcus multilocularis GPCR, family 2 0.0049 0.0179 0.018
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0039 0.0122 0.0123
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0236 0.1271 0.3859
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0027 0.4448
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.016 0.1257
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0816 0.4662 0.4688
Echinococcus multilocularis transfer RNA-Thr 0.0236 0.1271 0.1278
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0028 0.0059 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0344 0.2705
Loa Loa (eye worm) hypothetical protein 0.013 0.0654 0.0658
Echinococcus granulosus biogenic amine 5HT receptor 0.004 0.0129 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0051 0.0183
Loa Loa (eye worm) hypothetical protein 0.0058 0.0234 0.0235
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0051 0.0183
Echinococcus multilocularis serotonin receptor 0.004 0.0129 0.013
Brugia malayi RhoGAP domain containing protein 0.0343 0.1898 0.1908
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0028 0.0059 0.1816
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0268 0.0268
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0456 0.0459
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0028 0.0059 0.0059
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0236 0.1271 0.3859
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Onchocerca volvulus 0.004 0.0129 0.0359
Echinococcus multilocularis tachykinin peptides receptor 99D 0.004 0.0129 0.013
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0092 0.0721
Echinococcus granulosus tyrosine protein kinase csk 0.0236 0.1271 0.1278
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0051 0.0183
Loa Loa (eye worm) hypothetical protein 0.013 0.0654 0.0658
Brugia malayi Tensin 0.0343 0.1898 0.1908
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Echinococcus multilocularis NCK adaptor protein 0.0343 0.1898 0.1908
Brugia malayi Cation transporter family protein 0.0028 0.0059 0.0059
Giardia lamblia Kinase, NEK 0.0236 0.1271 1
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0696 0.3957 0.3979
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0236 0.1271 0.1278
Loa Loa (eye worm) hypothetical protein 0.013 0.0654 0.0658
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0058 0.0234 0.1839
Onchocerca volvulus 0.004 0.0129 0.0359
Echinococcus granulosus epidermal growth factor receptor 0.0236 0.1271 0.1278
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.5613 0.5645
Echinococcus multilocularis nmda type glutamate receptor 0.1168 0.6715 0.6753
Echinococcus granulosus atrial natriuretic peptide receptor 0.013 0.0654 0.0658
Onchocerca volvulus 0.0579 0.3275 1
Echinococcus granulosus serotonin transporter 0.0343 0.1896 0.1906
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0059 0.0059
Schistosoma mansoni histamine h1 receptor 0.004 0.0129 0.0129
Trypanosoma cruzi protein kinase, putative 0.0236 0.1271 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0129 0.0129
Brugia malayi Receptor family ligand binding region containing protein 0.0366 0.2031 0.2043
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0343 0.1898 0.1908
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0179 0.018
Echinococcus multilocularis neuropeptide Y receptor 0.004 0.0129 0.013
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0236 0.1271 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0344 0.2705
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0236 0.1271 0.1271
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.1271 0.1271
Entamoeba histolytica protein kinase domain containing protein 0.0252 0.1365 0.4146
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0051 0.0183
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0344 0.2705
Loa Loa (eye worm) TK protein kinase 0.0236 0.1271 0.1278
Echinococcus granulosus glycine receptor subunit beta 0.0028 0.0059 0.0059
Echinococcus multilocularis ferritin 0.0018 0.0001 0.0001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0129 0.0129
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0236 0.1271 0.1278
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0105 0.038
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0579 0.3275 1
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0344 0.2705
Schistosoma mansoni protein kinase 0.0236 0.1271 0.1271
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0321 0.1222
Echinococcus granulosus SH2 motif 0.0343 0.1898 0.1908
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0236 0.1271 0.1278
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0236 0.1272 0.3861
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0032 0.008 0.008
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0068 0.0292 0.0293
Echinococcus multilocularis metabotropic glutamate receptor 5 0.013 0.0654 0.0658
Schistosoma mansoni biogenic amine receptor 0.004 0.0129 0.0129
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0129 0.013
Echinococcus multilocularis neuropeptide receptor 0.004 0.0129 0.013
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Schistosoma mansoni serine/threonine RGC 0.0236 0.1271 0.1271
Echinococcus multilocularis ephrin type A receptor 4 A 0.0236 0.1271 0.1278
Loa Loa (eye worm) TK/INSR protein kinase 0.0236 0.1271 0.1278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0012 0.0041
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.004 0.0129 0.0129
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0058 0.0234 0.0234
Echinococcus multilocularis lamin dm0 0.0033 0.0084 0.0085
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0058 0.0234 0.0234
Toxoplasma gondii histone lysine methyltransferase SET1 0.0228 0.1223 0.9622
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.016 0.0577
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.004 0.0129 0.013
Plasmodium vivax vivapain-2 0.002 0.0012 0.0094
Loa Loa (eye worm) hypothetical protein 0.013 0.0654 0.0658
Echinococcus multilocularis tyrosine protein kinase shark 0.0579 0.3275 0.3293
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.1212 0.6975 0.7015
Schistosoma mansoni biogenic amine receptor 0.004 0.0129 0.0129
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0154 0.0795 0.0799
Echinococcus granulosus tyrosine kinase 0.0579 0.3275 0.3293
Brugia malayi Tachykinin-like peptides receptor 99D 0.004 0.0129 0.013
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Loa Loa (eye worm) hypothetical protein 0.0058 0.0234 0.0235
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0025 0.004 0.004
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0028 0.0059 0.0059
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0028 0.0059 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0105 0.038
Brugia malayi hypothetical protein 0.004 0.0129 0.013
Schistosoma mansoni tensin 0.0343 0.1898 0.1898
Schistosoma mansoni nAChR subunit 0.0028 0.0059 0.0059
Schistosoma mansoni GTPase activating protein 0.0343 0.1898 0.1898
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.1271 0.1271
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0579 0.3275 0.3293
Echinococcus granulosus tyrosine protein kinase Src42A 0.0579 0.3275 0.3293
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Schistosoma mansoni protein kinase 0.0236 0.1271 0.1271
Schistosoma mansoni shc transforming protein 0.0343 0.1898 0.1898
Brugia malayi Guanylyl cyclase protein 23 0.0366 0.2031 0.2043
Schistosoma mansoni glutamate receptor AMPA 0.0686 0.3902 0.3902
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Entamoeba histolytica hypothetical protein 0.0236 0.1272 0.3861
Schistosoma mansoni plexin 0.0088 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.016 0.1257
Schistosoma mansoni adapter molecule crk 0.0343 0.1898 0.1898
Onchocerca volvulus Putative nachr subunit 0.0028 0.0059 0.0144
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0072 0.026
Entamoeba histolytica hypothetical protein 0.0042 0.0137 0.0384
Echinococcus multilocularis somatostatin receptor 0.004 0.0129 0.013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0268 0.0268
Onchocerca volvulus 0.0028 0.0059 0.0144
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0058 0.0234 0.0235
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0012 0.0041
Loa Loa (eye worm) SH2 domain-containing protein 0.0343 0.1898 0.1908
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Echinococcus multilocularis c src tyrosine kinase 0.0579 0.3275 0.3293
Trichomonas vaginalis helicase, putative 0.0027 0.0051 0.0183
Schistosoma mansoni ferritin 0.0018 0.0001 0.0001
Brugia malayi C-terminal src kinase protein 1 0.0236 0.1271 0.1278
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0058 0.0234 0.1839
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Onchocerca volvulus 0.004 0.0129 0.0359
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0058 0.0234 0.0234
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.004 0.0129 0.0129
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0236 0.1271 0.1278
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0179 0.018
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0012 0.0012
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0028 0.0059 0.0059
Echinococcus granulosus neuropeptides capa receptor 0.004 0.0129 0.013
Leishmania major cathepsin L-like protease 0.002 0.0012 0.0094
Echinococcus granulosus alpha 1A adrenergic receptor 0.004 0.0129 0.013
Echinococcus granulosus g protein coupled receptor 0.004 0.0129 0.013
Echinococcus multilocularis epidermal growth factor receptor 0.0236 0.1271 0.1278
Echinococcus granulosus SHC transforming protein 3 0.0343 0.1898 0.1908
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Onchocerca volvulus 0.0343 0.1898 0.5779
Schistosoma mansoni tensin 0.0343 0.1898 0.1898
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.016 0.0453
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0137 0.0138
Plasmodium vivax amine transporter, putative 0.0058 0.0234 0.1839
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0321 0.0323
Echinococcus granulosus neuropeptide Y receptor 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0579 0.3275 0.3293
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0058 0.0234 0.0235
Toxoplasma gondii STE kinase 0.0236 0.1271 1
Onchocerca volvulus Huntingtin homolog 0.0134 0.0679 0.2046
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0343 0.1898 0.1908
Schistosoma mansoni amine GPCR 0.004 0.0129 0.0129
Brugia malayi F/Y-rich N-terminus family protein 0.0039 0.0119 0.012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0456 0.0456
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0343 0.1898 0.1898
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0816 0.4662 0.4688
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0058 0.0234 0.0234
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0321 0.1222
Plasmodium falciparum tyrosine kinase-like protein 0.0236 0.1271 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0179 0.018
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Brugia malayi hypothetical protein 0.004 0.0129 0.013
Loa Loa (eye worm) G-protein coupled receptor 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Brugia malayi follicle stimulating hormone receptor 0.004 0.0129 0.013
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0058 0.0234 0.0235
Schistosoma mansoni hypothetical protein 0.0049 0.0179 0.0179
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0028 0.0059 0.0059
Loa Loa (eye worm) TK protein kinase 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Brugia malayi Protein kinase domain containing protein 0.0579 0.3275 0.3293
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0028 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0058 0.0234 0.0235
Brugia malayi hypothetical protein 0.004 0.0129 0.013
Echinococcus granulosus SH2 motif 0.0343 0.1898 0.1908
Loa Loa (eye worm) hypothetical protein 0.0579 0.3275 0.3293
Brugia malayi RE15519p 0.004 0.0129 0.013
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.004 0.0129 0.0129
Echinococcus granulosus SH2 domain containing adapter protein F 0.0343 0.1898 0.1908
Echinococcus multilocularis tensin 0.0343 0.1898 0.1908
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0058 0.0234 0.0234
Echinococcus multilocularis integrin linked protein kinase 0.0236 0.1271 0.1278
Entamoeba histolytica hypothetical protein 0.0028 0.0059 0.0144
Schistosoma mansoni hypothetical protein 0.0049 0.0179 0.0179
Schistosoma mansoni hypothetical protein 0.0042 0.0137 0.0137
Echinococcus multilocularis dro:myosuppressin receptor 0.004 0.0129 0.013
Echinococcus multilocularis lysine specific demethylase 5A 0.0068 0.0292 0.0293
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0012 0.0041
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.016 0.0453
Schistosoma mansoni ephrin receptor 0.0236 0.1271 0.1271
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0322 0.0324
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0039 0.0122 0.0123
Trypanosoma brucei protein kinase, putative 0.0236 0.1271 1
Echinococcus granulosus dro:myosuppressin receptor 0.004 0.0129 0.013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0012 0.0041
Echinococcus granulosus SH2 domain containing protein 7 0.0343 0.1898 0.1908
Brugia malayi SRC-1 0.0579 0.3275 0.3293
Echinococcus granulosus c src tyrosine kinase 0.0579 0.3275 0.3293
Schistosoma mansoni hypothetical protein 0.0037 0.0107 0.0107
Echinococcus granulosus tyrosine protein kinase Fyn 0.0579 0.3275 0.3293
Brugia malayi Sema domain containing protein 0.0037 0.0107 0.0108
Plasmodium vivax vivapain-2 0.002 0.0012 0.0094
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0579 0.3275 0.3293
Onchocerca volvulus 0.0119 0.0589 0.1767
Mycobacterium leprae Probable lipase LipE 0.0073 0.0321 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0129 0.013
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Schistosoma mansoni ap endonuclease 0.0023 0.0027 0.0027
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0321 0.1222
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0032 0.008 0.008
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0344 0.2705
Brugia malayi Cathepsin L-like precursor 0.002 0.0012 0.0012
Schistosoma mansoni nAChR subunit 0.0028 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0236 0.1271 0.1278
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.004 0.0129 0.013
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0343 0.1898 0.1898
Brugia malayi Cation transporter family protein 0.0028 0.0059 0.0059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0456 0.0459
Schistosoma mansoni hypothetical protein 0.0105 0.051 0.051
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0321 1
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0084 0.0085
Schistosoma mansoni ferritin 0.0018 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0236 0.1271 0.1271
Loa Loa (eye worm) RGC/RGC protein kinase 0.0366 0.2031 0.2043
Schistosoma mansoni protein kinase 0.0236 0.1271 0.1271
Entamoeba histolytica ankyrin repeat protein 0.0236 0.1271 0.3859
Echinococcus granulosus intermediate filament protein 0.0033 0.0084 0.0085
Onchocerca volvulus 0.004 0.0129 0.0359
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0129
Brugia malayi hypothetical protein 0.004 0.0129 0.013
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0051 0.0183
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.013
Echinococcus multilocularis glycine receptor subunit beta 0.0028 0.0059 0.0059
Schistosoma mansoni tyrosine kinase 0.0579 0.3275 0.3275
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0106 0.0831
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0321 0.1161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0105 0.038
Echinococcus multilocularis hypothetical protein 0.0037 0.0107 0.0108
Onchocerca volvulus 0.004 0.0129 0.0359
Echinococcus granulosus tyrosine protein kinase Src42A 0.0343 0.1898 0.1908
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0321 0.1222
Brugia malayi beta-lactamase family protein 0.0073 0.0321 0.0323
Brugia malayi Variant SH3 domain containing protein 0.0343 0.1898 0.1908
Echinococcus multilocularis allatostatin A receptor 0.004 0.0129 0.013
Schistosoma mansoni tyrosine kinase 0.0579 0.3275 0.3275
Loa Loa (eye worm) TK/FER protein kinase 0.0579 0.3275 0.3293
Brugia malayi cytokine inducible SH2-containing protein 5 0.0343 0.1898 0.1908
Echinococcus multilocularis neuropeptide receptor A26 0.0596 0.3374 0.3393
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0579 0.3275 0.3293
Brugia malayi GnHR receptor homolog 0.004 0.0129 0.013
Loa Loa (eye worm) histone methyltransferase 0.0039 0.0122 0.0123
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0343 0.1898 0.1908
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0058 0.0234 0.0235
Echinococcus granulosus tumor protein p63 0.0329 0.1814 0.1824
Echinococcus multilocularis microtubule associated protein 2 0.0766 0.4367 0.4392
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0105 0.038
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Echinococcus multilocularis glutamate receptor 2 0.1258 0.7242 0.7283
Echinococcus granulosus tyrosine protein kinase HCK 0.0236 0.1271 0.1278
Entamoeba histolytica serine/threonine kinase, putative 0.0236 0.1271 0.3859
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Brugia malayi larval opioid receptor 0.004 0.0129 0.013
Echinococcus granulosus tyrosine protein kinase Lyn 0.0579 0.3275 0.3293
Echinococcus multilocularis geminin 0.0205 0.1089 0.1095
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Schistosoma mansoni neuropeptide receptor 0.004 0.0129 0.0129
Echinococcus multilocularis biogenic amine (5HT) receptor 0.004 0.0129 0.013
Brugia malayi Pre-SET motif family protein 0.0431 0.2413 0.2426
Loa Loa (eye worm) cysteine protease 0.002 0.0012 0.0012
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0236 0.1271 0.3859
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0051 0.0183
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0032 0.008 0.008
Loa Loa (eye worm) TK/EPH protein kinase 0.0236 0.1271 0.1278
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Brugia malayi Calcitonin receptor-like protein seb-1 0.0154 0.0795 0.0799
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0067 0.0239
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus granulosus tyrosine protein kinase Fyn 0.0579 0.3275 0.3293
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Echinococcus multilocularis alpha 1A adrenergic receptor 0.004 0.0129 0.013
Entamoeba histolytica tyrosin kinase, putative 0.0252 0.1365 0.4146
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.013 0.0654 0.0658
Echinococcus granulosus tyrosine protein kinase Fyn 0.0579 0.3275 0.3293
Brugia malayi SH2 domain containing protein 0.0343 0.1898 0.1908
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0084 0.0085
Schistosoma mansoni hypothetical protein 0.0049 0.0179 0.0179
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Loa Loa (eye worm) hypothetical protein 0.0236 0.1271 0.1278
Plasmodium falciparum tyrosine kinase-like protein 0.0236 0.1271 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0033 0.0084 0.0085
Schistosoma mansoni tensin-related 0.0343 0.1898 0.1898
Echinococcus granulosus ephrin type A receptor 4 A 0.0236 0.1271 0.1278
Plasmodium falciparum amino acid transporter, putative 0.0058 0.0234 0.1839
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0343 0.1898 0.1908
Onchocerca volvulus 0.0058 0.0234 0.068
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0579 0.3275 0.3293
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0179 0.018
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0236 0.1271 0.1278
Giardia lamblia GTOR 0.0046 0.016 0.1071
Echinococcus granulosus integrin linked protein kinase 0.0236 0.1271 0.1278
Brugia malayi Pre-SET motif family protein 0.0064 0.0268 0.027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0053 0.0189
Leishmania major cysteine peptidase A (CPA) 0.002 0.0012 0.0094
Brugia malayi Cathepsin L-like precursor 0.002 0.0012 0.0012
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Giardia lamblia Kinase 0.0236 0.1271 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0058 0.0234 0.1839
Trypanosoma cruzi extracellular receptor, putative 0.013 0.0654 0.5146
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Loa Loa (eye worm) hypothetical protein 0.0058 0.0234 0.0235
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.004 0.0129 0.0129
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0012 0.0041
Schistosoma mansoni SH2A 0.0343 0.1898 0.1898
Loa Loa (eye worm) STAT protein 0.0343 0.1898 0.1908
Schistosoma mansoni apoferritin-2 0.0018 0.0001 0.0001
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Echinococcus granulosus glutamate receptor 2 0.1004 0.5759 0.5791
Loa Loa (eye worm) hypothetical protein 0.0037 0.0107 0.0108
Loa Loa (eye worm) solute carrier family 6 member 4 0.0343 0.1896 0.1906
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0028 0.0059 0.0059
Onchocerca volvulus 0.004 0.0129 0.0359
Brugia malayi Protein kinase domain containing protein 0.0579 0.3275 0.3293
Onchocerca volvulus 0.0033 0.0084 0.0221
Giardia lamblia Kinase, NEK 0.0236 0.1271 1
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0431 0.2413 0.2426
Brugia malayi Dopamine receptor 0.004 0.0129 0.013
Onchocerca volvulus 0.0343 0.1898 0.5779
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.016 0.1257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0053 0.0189
Brugia malayi Sex muscle abnormal protein 5 0.0343 0.1898 0.1908
Toxoplasma gondii hypothetical protein 0.0058 0.0234 0.1839
Schistosoma mansoni nAChR subunit 0.0028 0.0059 0.0059
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0343 0.1898 0.1898
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.013
Schistosoma mansoni cpg binding protein 0.0126 0.0628 0.0628
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Schistosoma mansoni biogenic amine receptor 0.004 0.0129 0.0129
Leishmania major hypothetical protein, conserved 0.0236 0.1271 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0236 0.1271 0.1278
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0236 0.1271 0.3859
Loa Loa (eye worm) TK protein kinase 0.0236 0.1271 0.1278
Schistosoma mansoni lamin 0.0033 0.0084 0.0084
Echinococcus granulosus allatostatin A receptor 0.004 0.0129 0.013
Brugia malayi G-protein coupled receptor 0.004 0.0129 0.013
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0236 0.1271 0.1278
Brugia malayi AKH receptor 0.004 0.0129 0.013
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0236 0.1271 0.3859
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus multilocularis SHC transforming protein 3 0.0343 0.1898 0.1908
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0051 0.0183
Echinococcus granulosus semaphorin 5B 0.0037 0.0107 0.0108
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Entamoeba histolytica hypothetical protein 0.013 0.0654 0.1968
Loa Loa (eye worm) hypothetical protein 0.0037 0.0107 0.0108
Echinococcus granulosus expressed protein 0.0018 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.013
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0234 0.1839
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.1271 0.1271
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus granulosus g protein coupled receptor 0.004 0.0129 0.013
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0236 0.1271 0.1278
Onchocerca volvulus 0.0343 0.1898 0.5779
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0236 0.1271 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0028 0.0059 0.0463
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus granulosus g protein coupled receptor 0.004 0.0129 0.013
Plasmodium falciparum protein kinase, putative 0.0236 0.1271 1
Entamoeba histolytica serine/threonine kinase, putative 0.0236 0.1271 0.3859
Schistosoma mansoni myosin xvIII 0.004 0.0129 0.0129
Schistosoma mansoni nAChR subunit 0.0028 0.0059 0.0059
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.004 0.0129 0.013
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0236 0.1271 0.1278
Brugia malayi neuropeptide F receptor 0.004 0.0129 0.013
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.004 0.0129 0.013
Trichomonas vaginalis protein kinase atn1, putative 0.0236 0.1271 0.4607
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0012 0.0012
Echinococcus multilocularis musashi 0.0033 0.0084 0.0085
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0028 0.0059 0.0059
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0179 0.018
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0028 0.0059 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0012 0.0041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0051 0.0183
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0032 0.008 0.008
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Echinococcus multilocularis SH2 domain containing protein 7 0.0343 0.1898 0.1908
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.013
Loa Loa (eye worm) ctsf protein 0.002 0.0012 0.0012
Brugia malayi Furin-like cysteine rich region family protein 0.0236 0.1271 0.1278
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0154 0.0795 0.0799
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0579 0.3275 0.3293
Onchocerca volvulus 0.004 0.0129 0.0359
Echinococcus multilocularis tyrosine protein kinase csk 0.0236 0.1271 0.1278
Loa Loa (eye worm) beta-lactamase 0.0073 0.0321 0.0323
Echinococcus granulosus retinal guanylyl cyclase 2 0.0236 0.1271 0.1278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0012 0.0041
Echinococcus multilocularis NMDA receptor 0.0254 0.1377 0.1385
Onchocerca volvulus 0.0343 0.1898 0.5779
Brugia malayi intermediate filament protein 0.0033 0.0084 0.0085
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0028 0.0059 0.0059
Schistosoma mansoni ferritin light chain 0.0018 0.0001 0.0001
Echinococcus granulosus lamin dm0 0.0033 0.0084 0.0085
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Schistosoma mansoni nAChR subunit 0.0028 0.0059 0.0059
Echinococcus granulosus neuropeptide receptor 0.004 0.0129 0.013
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0012 0.0012
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Echinococcus granulosus metabotropic glutamate receptor 2 0.013 0.0654 0.0658
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0129
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0129
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0051 0.0183
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0028 0.0059 1
Echinococcus granulosus tm gpcr rhodopsin 0.004 0.0129 0.013
Echinococcus granulosus neuropeptide s receptor 0.0596 0.3374 0.3393
Echinococcus multilocularis glutamate receptor NMDA 0.0914 0.5232 0.5262
Loa Loa (eye worm) TK/FER protein kinase 0.0579 0.3275 0.3293
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0058 0.0234 0.0235
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0012 0.0012
Loa Loa (eye worm) plexin A 0.0104 0.0499 0.0501
Loa Loa (eye worm) TK/FAK protein kinase 0.0236 0.1271 0.1278
Brugia malayi G protein-coupled receptor F59B2.13 0.004 0.0129 0.013
Schistosoma mansoni amine GPCR 0.004 0.0129 0.0129
Echinococcus granulosus tyrosine protein kinase csk 0.0236 0.1271 0.1278
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0059 0.0059
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0058 0.0234 0.0235
Echinococcus multilocularis glutamate receptor 2 0.1004 0.5759 0.5791
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Echinococcus granulosus tensin 0.0343 0.1898 0.1908
Schistosoma mansoni hypothetical protein 0.004 0.0129 0.0129
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0343 0.1898 0.1908
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0321 0.0323
Schistosoma mansoni glutamate receptor NMDA 0.1212 0.6975 0.6975
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0037 0.0133
Leishmania major cathepsin L-like protease 0.0077 0.0344 0.2705
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus multilocularis insulin receptor 0.0236 0.1271 0.1278
Entamoeba histolytica hypothetical protein 0.0042 0.0137 0.0384
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0027 0.0209
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0012 0.0094
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0579 0.3275 0.3275
Loa Loa (eye worm) hypothetical protein 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Onchocerca volvulus Neuropeptide F receptor homolog 0.004 0.0129 0.0359
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Echinococcus multilocularis tyrosine protein kinase pr2 0.0236 0.1271 0.1278
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0012 0.0094
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0236 0.1271 0.1271
Entamoeba histolytica tyrosin kinase, putative 0.0236 0.1271 0.3859
Schistosoma mansoni protein kinase 0.0366 0.2031 0.2031
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.0059 0.0059
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0236 0.1271 0.3859
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0322 0.0322
Schistosoma mansoni tensin 0.0343 0.1898 0.1898
Onchocerca volvulus 0.0236 0.1271 0.3859
Brugia malayi Cathepsin L-like precursor 0.002 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Schistosoma mansoni opsin-like receptor 0.004 0.0129 0.0129
Schistosoma mansoni neuropeptide receptor 0.004 0.0129 0.0129
Brugia malayi Variant SH3 domain containing protein 0.0343 0.1898 0.1908
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0028 0.0059 0.0059
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0236 0.1271 0.1278
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0343 0.1898 0.1908
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0028 0.0059 0.0059
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0028 0.0059 0.0059
Entamoeba histolytica serine/threonine kinase, putative 0.0236 0.1271 0.3859
Leishmania major protein kinase, putative 0.0236 0.1271 1
Echinococcus multilocularis 0.0343 0.1898 0.1908
Echinococcus multilocularis neuropeptide s receptor 0.0596 0.3374 0.3393
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.016 0.1257
Schistosoma mansoni metabotropic glutamate receptor 0.013 0.0654 0.0654
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0012 0.0041
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0254 0.1377 0.1385
Loa Loa (eye worm) hypothetical protein 0.0051 0.0191 0.0193
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Loa Loa (eye worm) SH2 domain-containing protein 0.0343 0.1898 0.1908
Entamoeba histolytica ankyrin repeat protein 0.0236 0.1271 0.3859
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0321 0.2524
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus multilocularis protein tyrosine kinase 0.0236 0.1271 0.1278
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0579 0.3275 0.3293
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.004 0.0129 0.013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0012 0.0041
Schistosoma mansoni sodium-dependent amino acid transporter 0.0058 0.0234 0.0234
Echinococcus multilocularis metabotropic glutamate receptor 2 0.013 0.0654 0.0658
Giardia lamblia Protein 21.1 0.0236 0.1271 1
Brugia malayi Dopamine receptor protein 2 0.004 0.0129 0.013
Echinococcus granulosus expressed conserved protein 0.0343 0.1898 0.1908
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.013 0.0654 0.0658
Echinococcus multilocularis kinase suppressor of Ras 1 0.0236 0.1271 0.1278
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0129
Onchocerca volvulus 0.0236 0.1271 0.3859
Onchocerca volvulus 0.004 0.0129 0.0359
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0236 0.1271 0.1278
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0012 0.0012
Schistosoma mansoni amine GPCR 0.004 0.0129 0.0129
Echinococcus multilocularis tyrosine protein kinase csk 0.0236 0.1271 0.1278
Echinococcus granulosus glycine receptor subunit alpha 1 0.0028 0.0059 0.0059
Brugia malayi gonadotropin-releasing hormone receptor 2 0.004 0.0129 0.013
Echinococcus granulosus lamin 0.0033 0.0084 0.0085
Trichomonas vaginalis protein tyrosine kinase, putative 0.0236 0.1271 0.4607
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Echinococcus granulosus microtubule associated protein 2 0.0766 0.4367 0.4392
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.013 0.0654 0.0658
Echinococcus multilocularis neuropeptide Y receptor 0.004 0.0129 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0236 0.1271 0.4607
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0236 0.1271 0.1278
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0129
Schistosoma mansoni neuropeptide F-like receptor 0.004 0.0129 0.0129
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Onchocerca volvulus 0.0028 0.0059 0.0144
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Loa Loa (eye worm) RNA binding protein 0.0073 0.0322 0.0324
Brugia malayi integrin-linked kinase 0.0236 0.1271 0.1278
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Echinococcus multilocularis neuropeptide receptor 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0073 0.0321 0.0323
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0012 0.0012
Schistosoma mansoni adenoreceptor 0.004 0.0129 0.0129
Treponema pallidum sodium- and chloride- dependent transporter 0.0343 0.1896 1
Loa Loa (eye worm) TK/ACK protein kinase 0.0236 0.1271 0.1278
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0012 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.013
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0343 0.1898 0.1908
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0105 0.038
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.013
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0028 0.0059 0.0059
Brugia malayi Serotonin receptor 0.004 0.0129 0.013
Plasmodium vivax protein kinase, putative 0.0236 0.1271 1
Onchocerca volvulus 0.0058 0.0234 0.068
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0179 0.018
Loa Loa (eye worm) TK/FER protein kinase 0.0236 0.1271 0.1278
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0321 0.1222
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Brugia malayi G protein-coupled receptor 0.004 0.0129 0.013
Echinococcus granulosus retinal guanylyl cyclase 2 0.0236 0.1271 0.1278
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Entamoeba histolytica hypothetical protein 0.0236 0.1271 0.3859
Onchocerca volvulus 0.0579 0.3275 1
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.01 0.048 0.0483
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0058 0.0234 1
Entamoeba histolytica serine/threonine kinase, putative 0.0236 0.1271 0.3859
Echinococcus granulosus NCK adaptor protein 0.0343 0.1898 0.1908
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.004 0.0129 0.013
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Brugia malayi putative neuropeptide receptor 0.004 0.0129 0.013
Schistosoma mansoni ATP-binding cassette transporter 0.0686 0.3902 0.3902
Schistosoma mansoni growth factor receptor-bound protein 0.0343 0.1898 0.1898
Schistosoma mansoni lamin 0.0033 0.0084 0.0084
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0597 0.06
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0579 0.3275 0.3293
Trichomonas vaginalis STE family protein kinase 0.0236 0.1271 0.4607
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0236 0.1271 0.1278
Trichomonas vaginalis conserved hypothetical protein 0.0236 0.1271 0.4607
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0236 0.1271 0.1278
Echinococcus multilocularis glutamate receptor 2 0.1128 0.6481 0.6518
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0456 0.0456
Echinococcus multilocularis nAChR subunit 0.0028 0.0059 0.0059
Echinococcus multilocularis sodium and chloride dependent glycine 0.0058 0.0234 0.0235
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0467 0.2622 1
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0059 0.0463
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0236 0.1271 0.1278
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0268 0.0268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0344 0.2705
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0028 0.0059 0.0463
Brugia malayi Tyrosine-protein kinase PR2 0.0236 0.1271 0.1278
Brugia malayi hypothetical protein 0.004 0.0129 0.013
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.004 0.0129 0.013
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.0456 0.0459
Echinococcus multilocularis lamin 0.0033 0.0084 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.016 0.0577
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus granulosus muscleblind protein 0.1721 0.9944 1
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0254 0.1377 0.1385
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Loa Loa (eye worm) hypothetical protein 0.0343 0.1896 0.1906
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0343 0.1896 0.1906
Echinococcus multilocularis fmrfamide receptor 0.004 0.0129 0.013
Loa Loa (eye worm) TK/FER protein kinase 0.0236 0.1271 0.1278
Echinococcus granulosus activin receptor type 0.0236 0.1271 0.1278
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Toxoplasma gondii cathepsin CPL 0.002 0.0012 0.0094
Loa Loa (eye worm) TK/FER protein kinase 0.0236 0.1271 0.1278
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0012 0.0041
Echinococcus multilocularis receptor type guanylyl cyclase 0.0366 0.2031 0.2043
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0012 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0012 0.0041
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.004 0.0129 0.013
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0322 0.0322
Brugia malayi putative neuropeptide receptor NPR1 0.004 0.0129 0.013
Mycobacterium tuberculosis Conserved protein 0.0073 0.0321 0.1222
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Brugia malayi Cation transporter family protein 0.0028 0.0059 0.0059
Leishmania major cathepsin L-like protease 0.002 0.0012 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0051 0.0183
Entamoeba histolytica tyrosin kinase, putative 0.0236 0.1271 0.3859
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Loa Loa (eye worm) TK protein kinase 0.0236 0.1271 0.1278
Echinococcus multilocularis protein kinase 0.0236 0.1271 0.1278
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0028 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Echinococcus granulosus hypothetical protein 0.004 0.0129 0.013
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0236 0.1271 0.1278
Onchocerca volvulus 0.0064 0.0268 0.0785
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0007 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0037 0.0133
Onchocerca volvulus Huntingtin homolog 0.0134 0.0679 0.2046
Brugia malayi Serotonin receptor 0.004 0.0129 0.013
Brugia malayi hypothetical protein 0.004 0.0129 0.013
Echinococcus multilocularis growth factor receptor bound protein 2 0.0343 0.1898 0.1908
Schistosoma mansoni alpha-1 adrenergic receptor 0.004 0.0129 0.0129
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0344 0.2705
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.007 0.0305 0.2398
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0027 0.0027
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0343 0.1898 0.5779
Echinococcus multilocularis nmda type glutamate receptor 0.1044 0.5992 0.6026
Schistosoma mansoni suppressor of cytokine signaling 0.0343 0.1898 0.1898
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0152 0.0782 0.0786
Onchocerca volvulus 0.0343 0.1896 0.5773
Echinococcus granulosus sodium and chloride dependent glycine 0.0058 0.0234 0.0235
Echinococcus multilocularis tyrosine kinase 0.0579 0.3275 0.3293
Echinococcus granulosus retinal guanylyl cyclase 2 0.0236 0.1271 0.1278
Echinococcus granulosus signal transduction protein lnk realted 0.0343 0.1898 0.1908
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0129 0.013
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0579 0.3275 0.3293
Schistosoma mansoni hypothetical protein 0.004 0.0129 0.0129
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.0248 0.1947
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0344 0.2705
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0236 0.1271 0.1278
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0343 0.1898 0.1908
Schistosoma mansoni protein kinase 0.0236 0.1271 0.1271
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0236 0.1271 0.1278
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Leishmania major cathepsin L-like protease 0.002 0.0012 0.0094
Brugia malayi Protein kinase domain containing protein 0.0579 0.3275 0.3293
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Toxoplasma gondii hypothetical protein 0.0058 0.0234 0.1839
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0321 0.0323
Loa Loa (eye worm) TK/FER protein kinase 0.0236 0.1271 0.1278
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Plasmodium vivax tyrosine kinase-like protein, putative 0.0236 0.1271 1
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0236 0.1271 0.4607
Schistosoma mansoni plexin 0.0051 0.0191 0.0191
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.016 0.1257
Schistosoma mansoni cpg binding protein 0.0119 0.0589 0.0589
Mycobacterium leprae conserved hypothetical protein 0.0028 0.0059 0.1816
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0028 0.0059 0.0059
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0236 0.1271 0.1271
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Brugia malayi hypothetical protein 0.0236 0.1271 0.1278
Echinococcus multilocularis muscleblind protein 1 0.1721 0.9944 1
Onchocerca volvulus 0.0236 0.1271 0.3859
Schistosoma mansoni hypothetical protein 0.0037 0.0107 0.0107
Echinococcus multilocularis tyrosine kinase 0.0366 0.2031 0.2043
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Echinococcus granulosus cpg binding protein 0.0126 0.0628 0.0632
Echinococcus multilocularis glutamate receptor 4 0.0442 0.2474 0.2488
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Echinococcus granulosus glutamate receptor 2 0.1258 0.7242 0.7283
Echinococcus multilocularis tyrosine protein kinase Abl 0.0579 0.3275 0.3293
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.0456 0.0459
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0254 0.1377 0.1385
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0236 0.1271 0.4607
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Echinococcus granulosus tyrosine kinase 0.0366 0.2031 0.2043
Schistosoma mansoni tyrosine kinase 0.0579 0.3275 0.3275
Schistosoma mansoni protein kinase 0.0236 0.1271 0.1271
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Brugia malayi Variant SH3 domain containing protein 0.0343 0.1898 0.1908
Brugia malayi Immunoglobulin I-set domain containing protein 0.0236 0.1271 0.1278
Schistosoma mansoni vav2 0.0343 0.1898 0.1898
Schistosoma mansoni growth factor receptor-bound protein 0.0343 0.1898 0.1898
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0236 0.1271 0.1278
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0236 0.1271 0.3859
Loa Loa (eye worm) hypothetical protein 0.0154 0.0795 0.0799
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0322 0.0324
Echinococcus multilocularis activin receptor type 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus multilocularis glycine receptor subunit beta 0.0028 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Plasmodium falciparum protein kinase, putative 0.0236 0.1271 1
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Mycobacterium tuberculosis Conserved protein 0.0073 0.0321 0.1222
Entamoeba histolytica hypothetical protein 0.0236 0.1271 0.3859
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0051 0.0183
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.016 0.0577
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Schistosoma mansoni protein kinase 0.0236 0.1271 0.1271
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.016 0.0161
Toxoplasma gondii protein kinase domain-containing protein 0.0236 0.1271 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Schistosoma mansoni hypothetical protein 0.0049 0.0179 0.0179
Loa Loa (eye worm) TK/FER protein kinase 0.0236 0.1271 0.1278
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0343 0.1896 0.1896
Onchocerca volvulus 0.0037 0.0107 0.0293
Schistosoma mansoni biogenic amine (5HT) receptor 0.004 0.0129 0.0129
Echinococcus granulosus suppressor of cytokine signaling 6 0.0343 0.1898 0.1908
Onchocerca volvulus 0.0579 0.3275 1
Leishmania major hypothetical protein, conserved 0.0073 0.0321 0.2524
Brugia malayi SH2 domain containing protein 0.0579 0.3275 0.3293
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0254 0.1377 0.1385
Mycobacterium ulcerans hypothetical protein 0.0073 0.0321 1
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0028 0.0059 0.0059
Echinococcus granulosus thyrotropin releasing hormone receptor 0.004 0.0129 0.013
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.004 0.0129 0.013
Echinococcus granulosus protein kinase 0.0236 0.1271 0.1278
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0058 0.0234 0.0235
Schistosoma mansoni hypothetical protein 0.004 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Onchocerca volvulus 0.004 0.0129 0.0359
Loa Loa (eye worm) serine/threonine protein kinase 0.0236 0.1271 0.1278
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0137 0.0138
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0816 0.4662 0.4688
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0321 0.0321
Loa Loa (eye worm) hypothetical protein 0.0073 0.0321 0.0323
Loa Loa (eye worm) TK protein kinase 0.0236 0.1271 0.1278
Loa Loa (eye worm) hypothetical protein 0.0064 0.0268 0.027
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0343 0.1898 0.1908
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Onchocerca volvulus 0.0579 0.3275 1
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0321 1
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0322 0.0322
Echinococcus multilocularis tyrosine protein kinase csk 0.0236 0.1271 0.1278
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Echinococcus granulosus glutamate receptor 4 0.0442 0.2474 0.2488
Echinococcus granulosus suppressor of cytokine signaling 7 0.0343 0.1898 0.1908
Brugia malayi beta-lactamase 0.0073 0.0321 0.0323
Schistosoma mansoni amine GPCR 0.004 0.0129 0.0129
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0456 0.0456
Onchocerca volvulus 0.0058 0.0234 0.068
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0028 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0236 0.1271 0.1278
Loa Loa (eye worm) TK/FER protein kinase 0.0579 0.3275 0.3293
Leishmania major protein kinase, putative 0.0236 0.1271 1
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0236 0.1271 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0344 0.2705
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0028 0.0059 0.0222
Schistosoma mansoni suppressor of cytokine signaling 0.0343 0.1898 0.1898
Schistosoma mansoni tyrosine kinase 0.0579 0.3275 0.3275
Brugia malayi hypothetical protein 0.0343 0.1898 0.1908
Echinococcus multilocularis G protein coupled receptor 139 0.004 0.0129 0.013
Echinococcus granulosus tyrosine protein kinase csk 0.0236 0.1271 0.1278
Echinococcus granulosus neuropeptide Y receptor 0.004 0.0129 0.013
Schistosoma mansoni neuropeptide receptor 0.004 0.0129 0.0129
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0236 0.1271 1
Loa Loa (eye worm) hypothetical protein 0.0134 0.0679 0.0683
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0025 0.004 0.004
Onchocerca volvulus 0.0073 0.0321 0.0947
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Loa Loa (eye worm) TK/FER protein kinase 0.0579 0.3275 0.3293
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0322 0.0324
Loa Loa (eye worm) glutamate receptor 0.013 0.0654 0.0658
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Echinococcus granulosus N chimaerin 0.0343 0.1898 0.1908
Loa Loa (eye worm) TK protein kinase 0.0236 0.1271 0.1278
Schistosoma mansoni ferritin 0.0018 0.0001 0.0001
Brugia malayi TAR-binding protein 0.0073 0.0322 0.0324
Schistosoma mansoni biogenic amine (5HT) receptor 0.004 0.0129 0.0129
Schistosoma mansoni nAChR subunit 0.0028 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Loa Loa (eye worm) fibroinase 0.002 0.0012 0.0012
Echinococcus granulosus somatostatin receptor 0.004 0.0129 0.013
Schistosoma mansoni hypothetical protein 0.0343 0.1898 0.1898
Toxoplasma gondii exonuclease III APE 0.0023 0.0027 0.0209
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0579 0.3275 0.3293
Loa Loa (eye worm) TK/EGFR protein kinase 0.0236 0.1271 0.1278
Schistosoma mansoni glutamate receptor kainate 0.0686 0.3902 0.3902
Echinococcus multilocularis N chimaerin 0.0343 0.1898 0.1908
Onchocerca volvulus 0.0028 0.0059 0.0144
Echinococcus granulosus activated cdc42 kinase 1 0.0236 0.1271 0.1278
Echinococcus granulosus nmda type glutamate receptor 0.1044 0.5992 0.6026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0012 0.0041
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Echinococcus multilocularis g-protein coupled receptor 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0037 0.0107 0.0108
Schistosoma mansoni opsin-like receptor 0.004 0.0129 0.0129
Echinococcus multilocularis muscleblind protein 0.1721 0.9944 1
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0236 0.1271 0.1278
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0236 0.1271 0.1278
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0344 0.2705
Toxoplasma gondii protein kinase 0.0236 0.1271 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.013
Echinococcus granulosus tyrosine protein kinase pr2 0.0236 0.1271 0.1278
Schistosoma mansoni hypothetical protein 0.0348 0.1926 0.1926
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0343 0.1898 0.1908
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Echinococcus granulosus glutamate receptor NMDA 0.0914 0.5232 0.5262
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0129 0.013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0129
Loa Loa (eye worm) sema domain-containing protein 0.0037 0.0107 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0037 0.0133
Loa Loa (eye worm) hypothetical protein 0.0048 0.0175 0.0176
Brugia malayi protein-tyrosine kinase 0.0579 0.3275 0.3293
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0027 0.0808
Echinococcus multilocularis sex peptide receptor 0.004 0.0129 0.013
Entamoeba histolytica hypothetical protein 0.0042 0.0137 0.0384
Onchocerca volvulus 0.0048 0.0175 0.0499
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.004 0.0129 0.013
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.004 0.0129 0.013
Schistosoma mansoni hypothetical protein 0.004 0.0129 0.0129
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0027 0.0209
Onchocerca volvulus 0.0366 0.2031 0.6189
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0268 0.0268
Echinococcus granulosus geminin 0.0205 0.1089 0.1095
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0236 0.1271 0.1278
Schistosoma mansoni hypothetical protein 0.0343 0.1898 0.1898
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Echinococcus granulosus sex peptide receptor 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Echinococcus granulosus GPCR family 2 0.0049 0.0179 0.018
Brugia malayi Cathepsin L-like precursor 0.002 0.0012 0.0012
Onchocerca volvulus 0.0343 0.1898 0.5779
Loa Loa (eye worm) follicle stimulating hormone receptor 0.004 0.0129 0.013
Brugia malayi hypothetical protein 0.0236 0.1271 0.1278
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0058 0.0234 0.0235
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Brugia malayi hypothetical protein 0.0058 0.0234 0.0235
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.01 0.048 0.048
Schistosoma mansoni hypothetical protein 0.0205 0.1089 0.1089
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0579 0.3275 0.3293
Entamoeba histolytica hypothetical protein 0.0236 0.1271 0.3859
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0236 0.1271 0.1278
Loa Loa (eye worm) LGC-31 protein 0.0028 0.0059 0.0059
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0236 0.1271 0.1278
Onchocerca volvulus 0.0236 0.1271 0.3859
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0251 0.1359 0.1367
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0344 0.2705
Entamoeba histolytica tyrosin kinase, putative 0.0236 0.1271 0.3859
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0028 0.0059 0.1816
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0343 0.1898 0.1908
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Plasmodium falciparum protein kinase, putative 0.0236 0.1271 1
Entamoeba histolytica hypothetical protein 0.0042 0.0137 0.0384
Echinococcus multilocularis atrial natriuretic peptide receptor 0.013 0.0654 0.0658
Loa Loa (eye worm) TK/Met protein kinase 0.0236 0.1271 0.1278
Loa Loa (eye worm) TK/DDR protein kinase 0.0236 0.1271 0.1278
Onchocerca volvulus 0.0028 0.0059 0.0144
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0028 0.0059 0.0307
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0051 0.0183
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0028 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0073 0.0321 0.0323
Brugia malayi hypothetical protein 0.004 0.0129 0.013
Brugia malayi hypothetical protein 0.0037 0.0107 0.0108
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0321 0.1161
Trichomonas vaginalis AGC family protein kinase 0.0236 0.1271 0.4607
Schistosoma mansoni opsin-like receptor 0.004 0.0129 0.0129
Onchocerca volvulus 0.004 0.0129 0.0359
Echinococcus granulosus lysine specific demethylase 5A 0.0075 0.0331 0.0333
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.1271 0.1271
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0129 0.013
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Trypanosoma cruzi protein kinase, putative 0.0236 0.1271 1
Schistosoma mansoni apoferritin-2 0.0018 0.0001 0.0001
Onchocerca volvulus 0.0236 0.1271 0.3859
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0037 0.0133
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.0059 0.0059
Loa Loa (eye worm) TYRA-2 protein 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Schistosoma mansoni hypothetical protein 0.0205 0.1089 0.1089
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Trichomonas vaginalis CAMK family protein kinase 0.0236 0.1271 0.4607
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.1721 0.9944 1
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Brugia malayi neuropeptide F receptor 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Brugia malayi hypothetical protein 0.0152 0.0782 0.0786
Schistosoma mansoni ferritin light chain 0.0018 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0092 0.033
Loa Loa (eye worm) hypothetical protein 0.0105 0.051 0.0512
Brugia malayi SH2 domain containing protein 0.0343 0.1898 0.1908
Echinococcus granulosus sodium and chloride dependent glycine 0.0058 0.0234 0.0235
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0236 0.1271 0.1278
Onchocerca volvulus 0.004 0.0129 0.0359
Loa Loa (eye worm) ACC-1 protein 0.0028 0.0059 0.0059
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.004 0.0129 0.013
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.016 0.016
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0579 0.3275 0.3293
Brugia malayi G-protein coupled receptor 0.004 0.0129 0.013
Schistosoma mansoni glutamate receptor kainate 0.0686 0.3902 0.3902
Echinococcus granulosus 7tm_1 domain containing protein 0.004 0.0129 0.013
Entamoeba histolytica receptor protein kinase, putative 0.0236 0.1271 0.3859
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0321 0.0323
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0321 0.1161
Leishmania major cathepsin L-like protease 0.002 0.0012 0.0094
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.051 0.0512
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0236 0.1271 0.3859
Loa Loa (eye worm) RGC/RGC protein kinase 0.0236 0.1271 0.1278
Brugia malayi SH2 domain containing protein 0.0579 0.3275 0.3293
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Echinococcus granulosus tyrosine protein kinase Srms 0.0579 0.3275 0.3293
Loa Loa (eye worm) hypothetical protein 0.0037 0.0107 0.0108
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0012 0.0041
Echinococcus granulosus tyrosine protein kinase ABL1 0.0579 0.3275 0.3293
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0343 0.1898 0.1908
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0236 0.1271 0.1278
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0012 0.0094
Echinococcus multilocularis expressed protein 0.0018 0.0001 0.0001
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Onchocerca volvulus 0.0579 0.3275 1
Schistosoma mansoni hypothetical protein 0.0254 0.1377 0.1377
Schistosoma mansoni amine GPCR 0.004 0.0129 0.0129
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0028 0.0059 0.0059
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0058 0.0234 0.0235
Schistosoma mansoni glutamate receptor AMPA 0.0686 0.3902 0.3902
Entamoeba histolytica receptor protein kinase, putative 0.0236 0.1271 0.3859
Brugia malayi Cathepsin L-like precursor 0.002 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0051 0.0183
Loa Loa (eye worm) G-protein coupled receptor 0.004 0.0129 0.013
Onchocerca volvulus 0.0236 0.1271 0.3859
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0106 0.0831
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0579 0.3275 0.3293
Loa Loa (eye worm) TK/ROR protein kinase 0.0236 0.1271 0.1278
Schistosoma mansoni hypothetical protein 0.0051 0.0191 0.0191
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0058 0.0234 0.0235
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0051 0.0183
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Loa Loa (eye worm) protein kinase domain-containing protein 0.0236 0.1271 0.1278
Schistosoma mansoni signal transduction protein lnk-related 0.0343 0.1898 0.1898
Loa Loa (eye worm) hypothetical protein 0.0366 0.2031 0.2043
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.004 0.0129 0.0129
Schistosoma mansoni neuropeptide receptor 0.004 0.0129 0.0129
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.0059 0.0059
Echinococcus multilocularis orexin receptor type 2 0.004 0.0129 0.013
Entamoeba histolytica hypothetical protein 0.0236 0.1272 0.3861
Schistosoma mansoni growth hormone secretagogue receptor 0.004 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Onchocerca volvulus 0.0073 0.0321 0.0947
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0106 0.0831
Loa Loa (eye worm) ACC-1 protein 0.0028 0.0059 0.0059
Echinococcus granulosus protein tyrosine kinase 0.0236 0.1271 0.1278
Entamoeba histolytica protein kinase, putative 0.0236 0.1272 0.3861
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Schistosoma mansoni peptide (allatostatin)-like receptor 0.004 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0073 0.0321 0.0323
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0027 0.0027
Schistosoma mansoni protein kinase 0.0236 0.1271 0.1271
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0012 0.0041
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0028 0.0059 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0051 0.0183
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus granulosus neuropeptide receptor 0.004 0.0129 0.013
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.004 0.0129 0.013
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Loa Loa (eye worm) melatonin receptor type 1A 0.004 0.0129 0.013
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0236 0.1271 0.4607
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0053 0.0189
Echinococcus multilocularis g protein coupled receptor 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Onchocerca volvulus 0.0343 0.1898 0.5779
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.016 0.0161
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Echinococcus granulosus tachykinin peptides receptor 99D 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0442 0.2474 0.2488
Onchocerca volvulus Tyrosine kinase homolog 0.0236 0.1271 0.3859
Echinococcus granulosus metabotropic glutamate receptor 5 0.013 0.0654 0.0658
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0343 0.1898 0.1908
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0343 0.1898 0.5779
Echinococcus granulosus neuropeptide FF receptor 2 0.004 0.0129 0.013
Onchocerca volvulus 0.004 0.0129 0.0359
Leishmania major cathepsin L-like protease 0.002 0.0012 0.0094
Brugia malayi MH2 domain containing protein 0.012 0.0597 0.06
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0059 0.0463
Mycobacterium ulcerans lipase LipD 0.0073 0.0321 1
Echinococcus granulosus L aminoadipate semialdehyde 0.01 0.048 0.0483
Echinococcus granulosus neuropeptides capa receptor 0.004 0.0129 0.013
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0236 0.1271 0.1278
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Echinococcus granulosus glutamate receptor 1 0.0442 0.2474 0.2488
Brugia malayi Glutamate receptor 1 precursor 0.1128 0.6481 0.6518
Loa Loa (eye worm) hypothetical protein 0.0037 0.0107 0.0108
Brugia malayi hypothetical protein 0.0134 0.0679 0.0683
Echinococcus multilocularis g protein coupled receptor 0.004 0.0129 0.013
Brugia malayi sulfakinin receptor protein 0.004 0.0129 0.013
Leishmania major cathepsin L-like protease 0.0077 0.0344 0.2705
Loa Loa (eye worm) hypothetical protein 0.013 0.0654 0.0658
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Echinococcus multilocularis SH2 motif 0.0343 0.1898 0.1908
Echinococcus granulosus epidermal growth factor receptor 0.0236 0.1271 0.1278
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0004 0.0034
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0579 0.3275 0.3293
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0129
Entamoeba histolytica tyrosine kinase, putative 0.0236 0.1271 0.3859
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Loa Loa (eye worm) TK/FER protein kinase 0.0579 0.3275 0.3293
Echinococcus granulosus glutamate NMDA receptor subunit 0.1212 0.6975 0.7015
Loa Loa (eye worm) hypothetical protein 0.0032 0.0081 0.0081
Echinococcus granulosus growth factor receptor bound protein 2 0.0343 0.1898 0.1908
Brugia malayi Protein kinase domain containing protein 0.0579 0.3275 0.3293
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.013
Echinococcus multilocularis cysteine protease 0.002 0.0012 0.0012
Schistosoma mansoni neuropeptide f receptor 76f 0.004 0.0129 0.0129
Echinococcus multilocularis cpg binding protein 0.0126 0.0628 0.0632
Brugia malayi hypothetical protein 0.0037 0.0107 0.0108
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0321 0.1222
Echinococcus multilocularis raf serine:threonine protein kinase 0.0236 0.1271 0.1278
Echinococcus multilocularis natriuretic peptide receptor 1 0.0236 0.1271 0.1278
Brugia malayi Melatonin receptor type 1A 0.004 0.0129 0.013
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0236 0.1271 0.1278
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Echinococcus granulosus tyrosine kinase 0.0579 0.3275 0.3293
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0344 0.2705
Echinococcus granulosus tm gpcr rhodopsin 0.004 0.0129 0.013
Brugia malayi hypothetical protein 0.0042 0.0137 0.0138
Entamoeba histolytica SH2 domain containing protein 0.0343 0.1898 0.5779
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0236 0.1271 0.1278
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0037 0.0133
Leishmania major extracellular receptor, putative 0.013 0.0654 0.5146
Onchocerca volvulus 0.0028 0.0059 0.0144
Echinococcus granulosus tyrosine protein kinase Src64B 0.0579 0.3275 0.3293
Entamoeba histolytica protein kinase, putative 0.0236 0.1271 0.3859
Echinococcus multilocularis serotonin receptor 0.004 0.0129 0.013
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0236 0.1271 0.1278
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0028 0.0059 0.0059
Onchocerca volvulus 0.0033 0.0084 0.0221
Echinococcus granulosus receptor type guanylyl cyclase 0.0366 0.2031 0.2043
Echinococcus multilocularis FL cytokine receptor 0.0236 0.1271 0.1278
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.004 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0343 0.1898 0.1908
Brugia malayi Metabotropic glutamate receptor precursor. 0.013 0.0654 0.0658
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0051 0.0183
Brugia malayi Glutamate receptor 2 precursor 0.1128 0.6481 0.6518
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0268 0.027
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0129 0.013
Brugia malayi Protein kinase domain containing protein 0.0236 0.1271 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Brugia malayi Tyrosine-protein kinase abl-1 0.0579 0.3275 0.3293
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.013
Mycobacterium ulcerans beta-lactamase 0.0073 0.0321 1
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Loa Loa (eye worm) TK protein kinase 0.0236 0.1271 0.1278
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0028 0.0059 0.0059
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0058 0.0234 0.0234
Loa Loa (eye worm) TK/FER protein kinase 0.0579 0.3275 0.3293
Echinococcus granulosus hypothetical protein 0.0343 0.1898 0.1908
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0366 0.2031 0.6189
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.002 0.0155
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0028 0.0059 0.0059
Brugia malayi Protein kinase domain containing protein 0.0579 0.3275 0.3293
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0092 0.033
Echinococcus multilocularis tyrosine protein kinase HCK 0.0236 0.1271 0.1278
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Onchocerca volvulus 0.0236 0.1271 0.3859
Trichomonas vaginalis TKL family protein kinase 0.0236 0.1271 0.4607
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.004 0.0129 0.0129
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0331 0.0331
Brugia malayi jmjC domain containing protein 0.0075 0.0331 0.0333
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.1271 0.3859
Schistosoma mansoni tyrosine kinase 0.0236 0.1271 0.1271
Loa Loa (eye worm) SH2 domain-containing protein 0.0343 0.1898 0.1908
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.1258 0.7242 0.7283
Entamoeba histolytica cysteine surface protein, putative 0.0236 0.1271 0.3859
Loa Loa (eye worm) TK/FER protein kinase 0.0579 0.3275 0.3293
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.004 0.0129 0.0129
Brugia malayi Sema domain containing protein 0.0037 0.0107 0.0108
Echinococcus granulosus mixed lineage leukemia protein mll 0.0032 0.008 0.008
Trypanosoma brucei Flagellum attachment zone protein 20 0.0236 0.1271 1
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0321 0.2524

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -5.025 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.025 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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