Detailed information for compound 1776654

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 219.367 | Formula: C9H17NOS2
  • H donors: 1 H acceptors: 1 LogP: 3.74 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC[S+](CCCCN=C=S)[O-]
  • InChi: 1S/C9H17NOS2/c1-2-3-7-13(11)8-5-4-6-10-9-12/h2-8H2,1H3
  • InChiKey: WJYGVJJHEVMGBN-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi Dopamine receptor protein 2 0.0075 0.0082 0.0129
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.064 0.1103 0.1728
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Onchocerca volvulus 0.0039 0.0017 0.0041
Schistosoma mansoni hypothetical protein 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Schistosoma mansoni hypothetical protein 0.0052 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0083 0.0097 0.0097
Leishmania major fk506-binding protein 1-like protein 0.0053 0.0043 0.0257
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0029
Entamoeba histolytica hypothetical protein 0.0141 0.0202 0.0297
Brugia malayi SH2 domain containing protein 0.1428 0.2527 0.3958
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0067 0.0086
Echinococcus granulosus tachykinin peptides receptor 99D 0.0075 0.0082 0.0082
Loa Loa (eye worm) TK/INSR protein kinase 0.1004 0.176 0.1987
Schistosoma mansoni tyrosine kinase 0.2385 0.4254 0.4254
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.1428 0.2527 0.2853
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Schistosoma mansoni biogenic amine receptor 0.0075 0.0082 0.0082
Schistosoma mansoni suppressor of cytokine signaling 0.1428 0.2527 0.2527
Onchocerca volvulus 0.1428 0.2527 0.5939
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0075 0.0082 0.0082
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0496 0.0843 0.0843
Entamoeba histolytica serine/threonine kinase, putative 0.0956 0.1674 0.2608
Onchocerca volvulus 0.0084 0.0098 0.023
Loa Loa (eye worm) hypothetical protein 0.0043 0.0024 0.0027
Echinococcus granulosus tyrosine kinase 0.2385 0.4254 0.4254
Leishmania major carbonic anhydrase-like protein 0.0124 0.017 0.1014
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0158 0.0232 0.0345
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0075 0.0082 0.0082
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Echinococcus granulosus retinal guanylyl cyclase 2 0.0956 0.1674 0.1674
Echinococcus granulosus SH2 motif 0.1428 0.2527 0.2527
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Trypanosoma brucei protein kinase, putative 0.0956 0.1674 0.7755
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.064 0.1103 0.1103
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0956 0.1674 0.189
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0956 0.1674 0.2606
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0017 0.0017
Echinococcus granulosus tyrosine protein kinase csk 0.0956 0.1674 0.1674
Brugia malayi Steroid receptor seven-up type 2 0.0083 0.0097 0.0151
Schistosoma mansoni biogenic amine receptor 0.0075 0.0082 0.0082
Brugia malayi SH2 domain containing protein 0.1428 0.2527 0.3958
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus granulosus hypothetical protein 0.1428 0.2527 0.2527
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0075 0.0082 0.0082
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0141 0.0202 0.0294
Plasmodium vivax tyrosine kinase-like protein, putative 0.0956 0.1674 1
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0158 0.0232 0.0232
Onchocerca volvulus 0.0084 0.0098 0.023
Toxoplasma gondii FATC domain-containing protein 0.0158 0.0232 0.1387
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0269 0.0432 0.0658
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0067 0.0076
Loa Loa (eye worm) variant SH3 domain-containing protein 0.1428 0.2527 0.2853
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1225 0.2158 0.2158
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis protein kinase 0.0956 0.1674 0.1674
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) hypothetical protein 0.0084 0.0098 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0158 0.0232 0.0343
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.2385 0.4254 0.4254
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Schistosoma mansoni BC026374 protein (S09 family) 0.0084 0.0098 0.0098
Onchocerca volvulus 0.1428 0.2527 0.5939
Schistosoma mansoni amine oxidase 0.0043 0.0024 0.0024
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0141 0.0202 0.0202
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1674 0.189
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Schistosoma mansoni immunophilin 0.0053 0.0043 0.0043
Brugia malayi Tyrosine-protein kinase abl-1 0.2385 0.4254 0.6664
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0024 0.0141
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0083 0.0097 0.0151
Schistosoma mansoni alpha-1 adrenergic receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0062 0.0059 0.035
Giardia lamblia Hypothetical protein 0.0141 0.0202 0.046
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0956 0.1674 0.1674
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0197 0.0302 0.1398
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0039 0.0017 0.0017
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis fk506-binding protein, putative 0.0053 0.0043 0.0045
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus granulosus tyrosine protein kinase Src42A 0.2385 0.4254 0.4254
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Schistosoma mansoni nuclear receptor nhr-48 0.0039 0.0017 0.0017
Entamoeba histolytica cysteine surface protein, putative 0.0956 0.1674 0.2608
Onchocerca volvulus 0.0956 0.1674 0.3935
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.2593 0.4631 0.7248
Leishmania major hypothetical protein, unknown function 0.0141 0.0202 0.1204
Echinococcus granulosus epidermal growth factor receptor 0.1107 0.1946 0.1946
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Entamoeba histolytica SH2-protein kinase domain containing protein 0.1428 0.2527 0.3946
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0083 0.0097 0.0097
Echinococcus multilocularis tyrosine protein kinase Srms 0.2385 0.4254 0.4254
Echinococcus granulosus tyrosine protein kinase Srms 0.2385 0.4254 0.4254
Loa Loa (eye worm) hypothetical protein 0.0049 0.0034 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0221 0.0346 0.052
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus carboxylesterase 5A 0.0496 0.0843 0.0843
Brugia malayi Protein kinase domain containing protein 0.2385 0.4254 0.6664
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0956 0.1674 0.1674
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0017 0.0017
Onchocerca volvulus 0.0956 0.1674 0.3935
Loa Loa (eye worm) hypothetical protein 0.003 0 0.0001
Brugia malayi nuclear receptor RXR 0.0039 0.0017 0.0027
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0016 0.0016
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0043 0.0024 0.0141
Schistosoma mansoni tyrosine kinase 0.008 0.0092 0.0092
Schistosoma mansoni immunophilin 0.0046 0.003 0.003
Echinococcus multilocularis protein KINase family member (kin 25) 0.0956 0.1674 0.1674
Schistosoma mansoni ephrin receptor 0.0956 0.1674 0.1674
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Plasmodium falciparum protein kinase, putative 0.0956 0.1674 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0269 0.0432 0.0656
Onchocerca volvulus 0.2385 0.4254 1
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi SH2 domain containing protein 0.1428 0.2527 0.3958
Echinococcus multilocularis suppressor of cytokine signaling 7 0.1428 0.2527 0.2527
Brugia malayi Variant SH3 domain containing protein 0.1428 0.2527 0.3958
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.1428 0.2527 0.2527
Trichomonas vaginalis PIKK family atypical protein kinase 0.0224 0.0351 0.0529
Schistosoma mansoni hypothetical protein 0.0415 0.0696 0.0696
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Schistosoma mansoni SH2A 0.1428 0.2527 0.2527
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus granulosus tyrosine protein kinase Lyn 0.2385 0.4254 0.4254
Echinococcus multilocularis protein tyrosine kinase 0.0956 0.1674 0.1674
Toxoplasma gondii protein kinase domain-containing protein 0.0956 0.1674 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Trichomonas vaginalis PIKK family atypical protein kinase 0.0206 0.0318 0.0478
Onchocerca volvulus 0.0075 0.0082 0.0193
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0059 0.0059
Brugia malayi C-terminal src kinase protein 1 0.0956 0.1674 0.2622
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Schistosoma mansoni cpg binding protein 0.0059 0.0053 0.0053
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.0082 0.0082
Giardia lamblia Kinase, NEK 0.0956 0.1674 0.4734
Echinococcus granulosus lysine specific histone demethylase 1A 0.0043 0.0024 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.0097 0.0151
Echinococcus granulosus fmrfamide receptor 0.0075 0.0082 0.0082
Brugia malayi Tensin 0.1428 0.2527 0.3958
Brugia malayi Dopamine receptor 0.0075 0.0082 0.0129
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0014 0.0084
Loa Loa (eye worm) FKBP5 protein 0.0053 0.0043 0.0049
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0053 0.0043 0.0257
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0083 0.0097 0.0227
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0178 0.0268 0.1241
Echinococcus multilocularis transfer RNA-Thr 0.0956 0.1674 0.1674
Echinococcus granulosus peptide allatostatin:somatostatin 0.0075 0.0082 0.0082
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.5565 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Loa Loa (eye worm) carboxylesterase 0.0084 0.0098 0.0111
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Schistosoma mansoni growth factor receptor-bound protein 0.1428 0.2527 0.2527
Echinococcus granulosus g protein coupled receptor 0.0075 0.0082 0.0082
Onchocerca volvulus 0.0075 0.0082 0.0193
Schistosoma mansoni histamine h1 receptor 0.0075 0.0082 0.0082
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0075 0.0082 0.0082
Onchocerca volvulus 0.0043 0.0024 0.0056
Loa Loa (eye worm) hypothetical protein 0.0084 0.0098 0.0111
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.0097 0.0097
Schistosoma mansoni tyrosine kinase 0.2385 0.4254 0.4254
Schistosoma mansoni suppressor of cytokine signaling 0.1428 0.2527 0.2527
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0026 0.004
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0592 0.1015 0.6065
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0083 0.0097 0.0109
Schistosoma mansoni tensin-related 0.1428 0.2527 0.2527
Brugia malayi ecdysteroid receptor 0.0083 0.0097 0.0151
Brugia malayi ephrin receptor 1 precursor 0.0956 0.1674 0.2622
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0029
Echinococcus multilocularis serotonin receptor 0.0075 0.0082 0.0082
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0956 0.1674 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0213 0.0331 0.0498
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni serine/threonine RGC 0.0956 0.1674 0.1674
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0956 0.1674 0.1674
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Echinococcus multilocularis tyrosine protein kinase HCK 0.0956 0.1674 0.1674
Brugia malayi SH2 domain containing protein 0.1428 0.2527 0.3958
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0141 0.0202 0.0202
Entamoeba histolytica serine/threonine kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) hypothetical protein 0.0496 0.0843 0.0952
Schistosoma mansoni neuropeptide f receptor 76f 0.0075 0.0082 0.0082
Schistosoma mansoni tyrosine protein kinase 0.0956 0.1674 0.1674
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0053 0.0043 0.0257
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0053 0.0043 0.0045
Schistosoma mansoni nck2/grb4 0.1428 0.2527 0.2527
Leishmania major phosphatidylinositol kinase related protein, putative 0.0141 0.0202 0.1204
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0956 0.1674 0.1674
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2385 0.4254 0.4254
Trichomonas vaginalis conserved hypothetical protein 0.0956 0.1674 0.2606
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0141 0.0202 0.0316
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0956 0.1674 0.189
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Schistosoma mansoni thyroid hormone receptor 0.0355 0.0588 0.0588
Echinococcus multilocularis kinase suppressor of Ras 1 0.0956 0.1674 0.1674
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.1225 0.2158 0.3366
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1004 0.176 0.176
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0029
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni zinc finger protein 0.0039 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Onchocerca volvulus 0.0075 0.0082 0.0193
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Schistosoma mansoni protein tyrosine kinase 0.0956 0.1674 0.1674
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0059 0.0433
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0268 0.0399
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Entamoeba histolytica ankyrin repeat protein 0.0956 0.1674 0.2608
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0083 0.0097 0.0097
Schistosoma mansoni hypothetical protein 0.0172 0.0257 0.0257
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0044 0.0026 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0956 0.1674 0.1674
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0083 0.0097 0.0097
Schistosoma mansoni signal transduction protein lnk-related 0.1428 0.2527 0.2527
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0059 0.0433
Schistosoma mansoni hypothetical protein 0.0049 0.0034 0.0034
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0141 0.0202 0.0202
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Entamoeba histolytica hypothetical protein 0.0158 0.0232 0.0345
Echinococcus granulosus neuropeptide receptor A26 0.0075 0.0082 0.0082
Onchocerca volvulus 0.0083 0.0097 0.0227
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.0082 0.0082
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0956 0.1674 0.2622
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0956 0.1674 0.2622
Echinococcus multilocularis snurportin 1 0.032 0.0524 0.0524
Echinococcus multilocularis N chimaerin 0.1428 0.2527 0.2527
Echinococcus granulosus acetylcholinesterase 0.0496 0.0843 0.0843
Echinococcus multilocularis orexin receptor type 2 0.0075 0.0082 0.0082
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.0082 0.0082
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0039 0.0017 0.002
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0956 0.1674 0.189
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0043 0.0045
Schistosoma mansoni coup transcription factor 0.0083 0.0097 0.0097
Echinococcus granulosus para nitrobenzyl esterase 0.0084 0.0098 0.0098
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0075 0.0082 0.0093
Onchocerca volvulus 0.2385 0.4254 1
Echinococcus granulosus expressed protein 0.0379 0.0631 0.0631
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0067 0.0106
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0083 0.0097 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0083 0.0097 0.0151
Trypanosoma cruzi target of rapamycin kinase 3 0.0241 0.0382 0.0577
Brugia malayi sulfakinin receptor protein 0.0075 0.0082 0.0129
Loa Loa (eye worm) hypothetical protein 0.0084 0.0098 0.0111
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus granulosus g-protein coupled receptor 0.0075 0.0082 0.0082
Entamoeba histolytica tyrosin kinase, putative 0.0956 0.1674 0.2608
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.0097 0.0151
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0382 0.0577
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1428 0.2527 0.2527
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0017 0.0017
Echinococcus granulosus ecdysone induced protein 78C 0.0083 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0592 0.1015 0.1572
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0141 0.0202 0.0297
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.2002 0.3562 0.558
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.1225 0.2158 0.3366
Echinococcus multilocularis tensin 0.1428 0.2527 0.2527
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Schistosoma mansoni tyrosine kinase 0.2385 0.4254 0.4254
Echinococcus granulosus tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Giardia lamblia Kinase, NEK 0.0956 0.1674 0.4734
Echinococcus granulosus dnaJ subfamily B 0.0415 0.0696 0.0696
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0956 0.1674 0.1674
Loa Loa (eye worm) RGC/RGC protein kinase 0.0956 0.1674 0.189
Giardia lamblia Protein 21.1 0.0956 0.1674 0.4734
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0141 0.0202 0.0294
Echinococcus granulosus g protein coupled receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1428 0.2527 0.2527
Brugia malayi larval opioid receptor 0.0075 0.0082 0.0129
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Loa Loa (eye worm) carbonic anhydrase 3 0.0124 0.017 0.0192
Entamoeba histolytica serine/threonine kinase, putative 0.0956 0.1674 0.2608
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0382 0.0577
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0178 0.0268 0.0268
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Echinococcus granulosus tyrosine protein kinase Src42A 0.1428 0.2527 0.2527
Brugia malayi STAT protein, DNA binding domain containing protein 0.1428 0.2527 0.3958
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.0082 0.0082
Brugia malayi Immunoglobulin I-set domain containing protein 0.0956 0.1674 0.2622
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0956 0.1674 0.2606
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0062 0.0059 0.0092
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Onchocerca volvulus 0.2385 0.4254 1
Brugia malayi ecdysone receptor 0.0039 0.0017 0.0027
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0269 0.0432 0.0658
Brugia malayi bone morphogenetic protein type 1 receptor 0.0956 0.1674 0.2622
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Plasmodium falciparum protein kinase, putative 0.0956 0.1674 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0214 0.0333 0.05
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Schistosoma mansoni nuclear receptor 0.0039 0.0017 0.0017
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis nuclear receptor nhr 48 0.0039 0.0017 0.0017
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0141 0.0202 0.0202
Brugia malayi putative neuropeptide receptor NPR1 0.0075 0.0082 0.0129
Brugia malayi Carboxylesterase family protein 0.0084 0.0098 0.0153
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0956 0.1674 0.1674
Loa Loa (eye worm) phosphatidylinositol 3 0.1083 0.1903 0.2149
Brugia malayi hypothetical protein 0.0043 0.0024 0.0037
Leishmania major UDP-galactopyranose mutase 0.0043 0.0024 0.0141
Brugia malayi Protein kinase domain containing protein 0.1004 0.176 0.2757
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0075 0.0082 0.0082
Brugia malayi hypothetical protein 0.0037 0.0012 0.0019
Onchocerca volvulus 0.0075 0.0082 0.0193
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0027 0.0027
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1674 0.189
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0043 0.0024 0.0141
Schistosoma mansoni hypothetical protein 0.0075 0.0082 0.0082
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0141 0.0202 0.1204
Loa Loa (eye worm) hypothetical protein 0.2385 0.4254 0.4804
Loa Loa (eye worm) TK/RYK protein kinase 0.0956 0.1674 0.189
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0272 0.0438 0.0438
Schistosoma mansoni lipoxygenase 0.0056 0.0048 0.0048
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Giardia lamblia Phosphatidylinositol 4-kinase 0.0141 0.0202 0.046
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Loa Loa (eye worm) solute carrier family 6 member 4 0.0153 0.0223 0.0252
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0369 0.0557
Brugia malayi Protein kinase domain containing protein 0.2385 0.4254 0.6664
Echinococcus multilocularis sex peptide receptor 0.0075 0.0082 0.0082
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) nuclear receptor NHR-67 0.0039 0.0017 0.002
Echinococcus granulosus SH2 motif 0.1428 0.2527 0.2527
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Echinococcus granulosus biogenic amine 5HT receptor 0.0075 0.0082 0.0082
Entamoeba histolytica ankyrin repeat protein 0.0956 0.1674 0.2608
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0082 0.0082
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0158 0.0232 0.1074
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0053 0.0043 0.0067
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0158 0.0232 0.0343
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) hypothetical protein 0.0141 0.0202 0.0228
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0049 0.0034 0.0031
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni hypothetical protein 0.0037 0.0012 0.0012
Onchocerca volvulus 0.0039 0.0017 0.0041
Brugia malayi tRNA modification GTPase TrmE family protein 0.1428 0.2527 0.3958
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0083 0.0097 0.0109
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis para nitrobenzyl esterase 0.0084 0.0098 0.0098
Echinococcus multilocularis serotonin receptor 0.0075 0.0082 0.0082
Entamoeba histolytica SH2 domain containing protein 0.1428 0.2527 0.3946
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0369 0.0557
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni nuclear receptor 0.0039 0.0017 0.0017
Loa Loa (eye worm) STAT protein 0.1428 0.2527 0.2853
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0141 0.0202 0.1204
Brugia malayi Serotonin receptor 0.0075 0.0082 0.0129
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.1961 0.3488 1
Echinococcus multilocularis activated cdc42 kinase 1 0.0956 0.1674 0.1674
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0269 0.0432 0.0432
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0075 0.0082 0.0129
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0956 0.1674 0.7755
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0026 0.004
Schistosoma mansoni neuropeptide receptor 0.0075 0.0082 0.0082
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0565 0.0966 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0269 0.0432 0.0488
Echinococcus multilocularis integrin linked protein kinase 0.0956 0.1674 0.1674
Schistosoma mansoni myosin xvIII 0.0075 0.0082 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0141 0.0202 0.0294
Entamoeba histolytica tyrosin kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis protein kinase atn1, putative 0.0956 0.1674 0.2606
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0084 0.0098 0.0098
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.1428 0.2527 0.2527
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1428 0.2527 0.2527
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi neuropeptide F receptor 0.0075 0.0082 0.0129
Loa Loa (eye worm) protein kinase domain-containing protein 0.0956 0.1674 0.189
Echinococcus granulosus carbonic anhydrase II 0.0124 0.017 0.017
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0956 0.1674 0.2608
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0141 0.0202 0.0202
Loa Loa (eye worm) RGC/RGC protein kinase 0.0956 0.1674 0.189
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.0148 0.0885
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Echinococcus granulosus tyrosine protein kinase HCK 0.0956 0.1674 0.1674
Schistosoma mansoni biogenic amine (5HT) receptor 0.0075 0.0082 0.0082
Echinococcus granulosus neuropeptide FF receptor 2 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.3564 0.6384 1
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0053 0.0043 0.0045
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0153 0.0223 0.035
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0059 0.0059
Onchocerca volvulus 0.0956 0.1674 0.3935
Echinococcus multilocularis raf serine:threonine protein kinase 0.0956 0.1674 0.1674
Echinococcus granulosus orexin receptor type 2 0.0075 0.0082 0.0082
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0592 0.1015 0.6065
Echinococcus multilocularis signal transduction protein lnk realted 0.1428 0.2527 0.2527
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0067 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0382 0.0577
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1562 0.2768 0.4325
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Echinococcus multilocularis activin receptor type 0.0956 0.1674 0.1674
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0158 0.0232 0.0343
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.1428 0.2527 0.2527
Echinococcus multilocularis SHC transforming protein 3 0.1428 0.2527 0.2527
Brugia malayi orphan nuclear receptor NR2E1 0.0039 0.0017 0.0027
Giardia lamblia GTOR 0.0269 0.0432 0.1129
Brugia malayi nuclear hormone receptor 0.0039 0.0017 0.0027
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0084 0.0098 0.0098
Mycobacterium ulcerans carboxylesterase, LipT 0.0084 0.0098 0.0814
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0083 0.0097 0.0097
Loa Loa (eye worm) TK/EGFR protein kinase 0.1107 0.1946 0.2197
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Entamoeba histolytica protein kinase, putative 0.1428 0.2527 0.3946
Plasmodium vivax hypothetical protein 0.0141 0.0202 0.1204
Echinococcus multilocularis tyrosine protein kinase csk 0.0956 0.1674 0.1674
Echinococcus granulosus SH2 domain containing protein 7 0.1428 0.2527 0.2527
Loa Loa (eye worm) steroid hormone receptor 0.0083 0.0097 0.0109
Trypanosoma brucei Flagellum attachment zone protein 20 0.0956 0.1674 0.7755
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0141 0.0202 0.1204
Echinococcus granulosus cpg binding protein 0.0062 0.0059 0.0059
Plasmodium falciparum protoporphyrinogen oxidase 0.0043 0.0024 0.0141
Echinococcus multilocularis tyrosine kinase 0.2385 0.4254 0.4254
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0083 0.0097 0.0097
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0153 0.0223 0.0223
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0083 0.0097 0.0109
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trichomonas vaginalis conserved hypothetical protein 0.0956 0.1674 0.2606
Loa Loa (eye worm) hypothetical protein 0.0084 0.0098 0.0111
Schistosoma mansoni hypothetical protein 0.0075 0.0082 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0083 0.0097 0.0151
Entamoeba histolytica tyrosin kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0956 0.1674 0.2606
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0141 0.0202 0.0294
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Echinococcus granulosus activated cdc42 kinase 1 0.0956 0.1674 0.1674
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0956 0.1674 0.1674
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0956 0.1674 0.1674
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0043 0.0024 0.0141
Echinococcus granulosus neuroligin 0.0084 0.0098 0.0098
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0053 0.0043 0.0048
Loa Loa (eye worm) TK/EPH protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis tyrosine protein kinase pr2 0.0956 0.1674 0.1674
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus granulosus FTZ F1 alpha 0.0083 0.0097 0.0097
Brugia malayi Carboxylesterase family protein 0.0496 0.0843 0.1321
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.0097 0.0097
Brugia malayi RE15519p 0.0075 0.0082 0.0129
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0592 0.1015 0.1015
Loa Loa (eye worm) hypothetical protein 0.0046 0.003 0.0034
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0269 0.0432 0.0656
Schistosoma mansoni tyrosine kinase 0.2385 0.4254 0.4254
Loa Loa (eye worm) hypothetical protein 0.0153 0.0223 0.0252
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0956 0.1674 0.1674
Brugia malayi G-protein coupled receptor 0.0075 0.0082 0.0129
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.0082 0.0093
Schistosoma mansoni growth hormone secretagogue receptor 0.0075 0.0082 0.0082
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0178 0.0268 0.0268
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Onchocerca volvulus 0.1428 0.2527 0.5939
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0141 0.0202 0.0202
Onchocerca volvulus 0.0084 0.0098 0.023
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Entamoeba histolytica hypothetical protein, conserved 0.0956 0.1674 0.2608
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0956 0.1674 1
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0141 0.0202 0.0932
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0141 0.0202 0.0202
Leishmania major protein kinase, putative 0.0956 0.1674 1
Loa Loa (eye worm) hypothetical protein 0.0496 0.0843 0.0952
Schistosoma mansoni gliotactin 0.0084 0.0098 0.0098
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0067 0.0084
Brugia malayi hypothetical protein 0.0049 0.0034 0.0053
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Onchocerca volvulus 0.2385 0.4254 1
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) RhoGAP domain-containing protein 0.1428 0.2527 0.2853
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0124 0.017 0.017
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0084 0.0098 0.0132
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Trypanosoma brucei Pseudokinase, putative 0.0956 0.1674 0.7755
Trichomonas vaginalis PIKK family atypical protein kinase 0.0206 0.0319 0.0478
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0956 0.1674 0.1674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0369 0.0557
Echinococcus multilocularis tyrosine protein kinase csk 0.0956 0.1674 0.1674
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0956 0.1674 0.189
Loa Loa (eye worm) hypothetical protein 0.0043 0.0024 0.0027
Loa Loa (eye worm) SRC-1 0.2385 0.4254 0.4804
Loa Loa (eye worm) norepinephrine transporter 0.0153 0.0223 0.0252
Entamoeba histolytica receptor protein kinase, putative 0.0956 0.1674 0.2608
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.0097 0.0151
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0158 0.0232 0.0232
Echinococcus granulosus tyrosine kinase 0.2385 0.4254 0.4254
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0083 0.0097 0.0109
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Schistosoma mansoni fkbp-rapamycin associated protein 0.0158 0.0232 0.0232
Echinococcus multilocularis geminin 0.0172 0.0257 0.0257
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0956 0.1674 0.2606
Trichomonas vaginalis PIKK family atypical protein kinase 0.0158 0.0232 0.0343
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Echinococcus multilocularis c src tyrosine kinase 0.2385 0.4254 0.4254
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0083 0.0097 0.0097
Loa Loa (eye worm) serine/threonine protein kinase 0.0956 0.1674 0.189
Trichomonas vaginalis CAMK family protein kinase 0.0956 0.1674 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Onchocerca volvulus 0.0956 0.1674 0.3935
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis receptor type guanylyl cyclase 0.0956 0.1674 0.1674
Onchocerca volvulus 0.0075 0.0082 0.0193
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.0492 0.0836 0.0836
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0075 0.0082 0.0129
Brugia malayi G protein-coupled receptor F59B2.13 0.0075 0.0082 0.0129
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Brugia malayi RNA, U transporter 1 0.0085 0.01 0.0157
Loa Loa (eye worm) hypothetical protein 0.0495 0.0841 0.095
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus multilocularis ecdysone induced protein 78C 0.0083 0.0097 0.0097
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0075 0.0082 0.0082
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0158 0.0232 0.0364
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0141 0.0202 0.1204
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0083 0.0097 0.0097
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0075 0.0082 0.0082
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0124 0.017 0.0244
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0269 0.0432 0.1999
Echinococcus multilocularis insulin receptor 0.1004 0.176 0.176
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0014 0.5
Schistosoma mansoni tensin 0.1428 0.2527 0.2527
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Onchocerca volvulus 0.0209 0.0325 0.0763
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Schistosoma mansoni growth factor receptor-bound protein 0.1428 0.2527 0.2527
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0017 0.0017
Echinococcus multilocularis tyrosine protein kinase Fgr 0.2385 0.4254 0.4254
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0053 0.0043 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0158 0.0232 0.0343
Brugia malayi nuclear receptor NHR-88 0.0039 0.0017 0.0027
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.064 0.1103 0.1709
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0048 0.0048
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.3564 0.6384 1
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Onchocerca volvulus 0.0141 0.0202 0.0474
Brugia malayi SWIRM domain containing protein 0.0043 0.0024 0.0037
Echinococcus granulosus N chimaerin 0.1428 0.2527 0.2527
Brugia malayi G-protein coupled receptor 0.0075 0.0082 0.0129
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Onchocerca volvulus Protein ultraspiracle homolog 0.0083 0.0097 0.0227
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0158 0.0232 0.0364
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis cpg binding protein 0.0062 0.0059 0.0059
Trypanosoma cruzi UDP-galactopyranose mutase 0.0043 0.0024 0.0015
Brugia malayi G protein-coupled receptor 0.0075 0.0082 0.0129
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0956 0.1674 0.2622
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0043 0.0197
Leishmania major hypothetical protein, conserved 0.0141 0.0202 0.1204
Schistosoma mansoni tyrosine kinase 0.1037 0.1819 0.1819
Echinococcus granulosus NCK adaptor protein 0.1428 0.2527 0.2527
Echinococcus multilocularis thyroid hormone receptor alpha 0.0355 0.0588 0.0588
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0053 0.006
Schistosoma mansoni tensin-related 0.1428 0.2527 0.2527
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0269 0.0432 0.0676
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0039 0.0017 0.0017
Brugia malayi RhoGAP domain containing protein 0.1428 0.2527 0.3958
Onchocerca volvulus 0.0956 0.1674 0.3935
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0141 0.0202 0.0316
Schistosoma mansoni GTPase activating protein 0.1428 0.2527 0.2527
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.1428 0.2527 0.5939
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.2385 0.4254 0.4254
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) DR-78 0.0039 0.0017 0.002
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Brugia malayi nuclear receptor RXR 0.0044 0.0026 0.004
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0053 0.0043 0.0197
Loa Loa (eye worm) hypothetical protein 0.0043 0.0024 0.0027
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.064 0.1103 0.1103
Onchocerca volvulus 0.0075 0.0082 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0369 0.0557
Onchocerca volvulus 0.2385 0.4254 1
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0178 0.0268 0.0399
Leishmania major phosphatidylinositol 4-kinase, putative 0.0141 0.0202 0.1204
Trichomonas vaginalis AGC family protein kinase 0.0956 0.1674 0.2606
Brugia malayi photoreceptor-specific nuclear receptor 0.0083 0.0097 0.0151
Schistosoma mansoni amine GPCR 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0043 0.0024 0.0027
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0075 0.0082 0.0082
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0017 0.0027
Schistosoma mansoni tyrosine kinase 0.1004 0.176 0.176
Brugia malayi Dopamine receptor protein 1 0.0075 0.0082 0.0129
Schistosoma mansoni tyrosine kinase 0.008 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Echinococcus granulosus tyrosine protein kinase csk 0.0956 0.1674 0.1674
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0592 0.1015 0.6065
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Brugia malayi Guanylyl cyclase protein 23 0.0956 0.1674 0.2622
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0075 0.0082 0.0082
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0141 0.0202 0.1204
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0268 0.0399
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0268 0.0399
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Plasmodium falciparum tyrosine kinase-like protein 0.0956 0.1674 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.0097 0.0097
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0124 0.017 0.0244
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Loa Loa (eye worm) inositol-1 0.0037 0.0014 0.0016
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0075 0.0082 0.0093
Brugia malayi Nuclear hormone receptor-like 1 0.0083 0.0097 0.0151
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0027 0.0027
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1428 0.2527 0.2527
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0046 0.003 0.018
Brugia malayi Carboxylesterase family protein 0.0084 0.0098 0.0153
Trichomonas vaginalis protein tyrosine kinase, putative 0.0956 0.1674 0.2606
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Loa Loa (eye worm) serotonin transporter b 0.0153 0.0223 0.0252
Echinococcus multilocularis neuropeptide receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.064 0.1103 0.1709
Loa Loa (eye worm) hypothetical protein 0.0495 0.0841 0.095
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0241 0.0382 0.1767
Brugia malayi AKH receptor 0.0075 0.0082 0.0129
Loa Loa (eye worm) TK/ABL protein kinase 0.2385 0.4254 0.4804
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis SH2 motif 0.1428 0.2527 0.2527
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0141 0.0202 0.0932
Schistosoma mansoni tyrosine kinase 0.2385 0.4254 0.4254
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.0082 0.0093
Plasmodium falciparum importin beta, putative 0.003 0 0.0003
Loa Loa (eye worm) carboxylesterase 0.0496 0.0843 0.0952
Brugia malayi Furin-like cysteine rich region family protein 0.1107 0.1946 0.3048
Echinococcus granulosus SHC transforming protein 3 0.1428 0.2527 0.2527
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0141 0.0202 0.0294
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0272 0.0438 0.0438
Schistosoma mansoni tyrosine kinase 0.1037 0.1819 0.1819
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0029
Schistosoma mansoni amine GPCR 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0083 0.0097 0.0097
Entamoeba histolytica serine/threonine kinase, putative 0.0956 0.1674 0.2608
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0141 0.0202 0.0294
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.2195 0.3911 0.3911
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Brugia malayi Carboxylesterase family protein 0.0496 0.0843 0.1321
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0014 0.0003
Echinococcus granulosus fibroblast growth factor receptor 4 0.0956 0.1674 0.1674
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0956 0.1674 1
Echinococcus granulosus tyrosine protein kinase Fps85D 0.2385 0.4254 0.4254
Entamoeba histolytica serine/threonine kinase, putative 0.0956 0.1674 0.2608
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Schistosoma mansoni nuclear hormone receptor 0.0083 0.0097 0.0097
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0083 0.0097 0.0097
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0774 0.1345 0.3779
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Schistosoma mansoni hypothetical protein 0.0272 0.0438 0.0438
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0124 0.017 0.0266
Loa Loa (eye worm) hypothetical protein 0.0161 0.0238 0.0268
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0956 0.1674 0.3935
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0956 0.1674 0.1674
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) hypothetical protein 0.1369 0.2419 0.2731
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0592 0.1015 0.1574
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0017 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Brugia malayi hypothetical protein 0.0956 0.1674 0.2622
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0083 0.0097 0.0097
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0017 0.0017
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0075 0.0082 0.0082
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Loa Loa (eye worm) SH2 domain-containing protein 0.1428 0.2527 0.2853
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0027 0.003
Loa Loa (eye worm) TK/DDR protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis 0.1428 0.2527 0.2527
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0083 0.0097 0.0109
Schistosoma mansoni phosphatidylinositol 4-kinase 0.064 0.1103 0.1103
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0075 0.0082 0.0082
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0053 0.0043 0.0067
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0269 0.0432 0.0656
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0956 0.1674 0.1674
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Mycobacterium ulcerans oxidoreductase 0.0043 0.0024 0.0093
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1004 0.176 0.176
Loa Loa (eye worm) TYRA-2 protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) melatonin receptor type 1A 0.0075 0.0082 0.0093
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Loa Loa (eye worm) hypothetical protein 0.0153 0.0223 0.0252
Schistosoma mansoni amine GPCR 0.0075 0.0082 0.0082
Toxoplasma gondii target of rapamycin (TOR), putative 0.0234 0.0369 0.2203
Schistosoma mansoni cpg binding protein 0.0062 0.0059 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0169 0.0252 0.0373
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.0082 0.0082
Brugia malayi SH2 domain containing protein 0.1428 0.2527 0.3958
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0592 0.1015 0.6065
Echinococcus multilocularis neuropeptide receptor A26 0.0075 0.0082 0.0082
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0075 0.0082 0.0082
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis tyrosine protein kinase 0.0956 0.1674 0.1674
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2385 0.4254 0.4254
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0141 0.0202 0.0202
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0956 0.1674 0.7755
Schistosoma mansoni tyrosine-protein kinase zap-70 0.1428 0.2527 0.2527
Echinococcus granulosus activin receptor type 0.0956 0.1674 0.1674
Schistosoma mansoni tyrosine kinase 0.008 0.0092 0.0092
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0075 0.0082 0.0093
Echinococcus granulosus SH2 domain containing adapter protein F 0.1428 0.2527 0.2527
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0046 0.003 0.003
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.2931 0.5241 0.8206
Brugia malayi Protein kinase domain containing protein 0.2385 0.4254 0.6664
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0027 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0024 0.0141
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0141 0.0202 0.1204
Loa Loa (eye worm) nuclear hormone receptor 0.0039 0.0017 0.002
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0053 0.0043 0.0043
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Brugia malayi GnHR receptor homolog 0.0075 0.0082 0.0129
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.079 0.1373 0.1373
Echinococcus granulosus allatostatin A receptor 0.0075 0.0082 0.0082
Echinococcus granulosus tensin C1 domain containing phosphatase 0.1428 0.2527 0.2527
Brugia malayi nuclear hormone receptor 0.0083 0.0097 0.0151
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0124 0.017 0.017
Entamoeba histolytica hypothetical protein 0.2931 0.5241 0.8206
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Mycobacterium ulcerans dehydrogenase 0.0043 0.0024 0.0093
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.1428 0.2527 0.2527
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.032 0.0524 0.0591
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0141 0.0202 0.0202
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0043 0.0024 0.0855
Echinococcus granulosus hypothetical protein 0.0075 0.0082 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0369 0.0557
Brugia malayi protein-tyrosine kinase 0.2385 0.4254 0.6664
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0044 0.0026 0.0029
Loa Loa (eye worm) protein-tyrosine phosphatase 0.1428 0.2527 0.2853
Onchocerca volvulus 0.0075 0.0082 0.0193
Echinococcus granulosus receptor type guanylyl cyclase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Onchocerca volvulus 0.0075 0.0082 0.0193
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0592 0.1015 0.1015
Echinococcus granulosus nuclear receptor nhr 48 0.0039 0.0017 0.0017
Brugia malayi SH2 domain containing protein 0.1428 0.2527 0.3958
Trichomonas vaginalis conserved hypothetical protein 0.0956 0.1674 0.2606
Echinococcus multilocularis G protein coupled receptor 139 0.0075 0.0082 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.0097 0.0151
Schistosoma mansoni sodium/chloride dependent transporter 0.0153 0.0223 0.0223
Onchocerca volvulus 0.0084 0.0098 0.023
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0039 0.0017 0.0017
Echinococcus granulosus natriuretic peptide receptor 1 0.0956 0.1674 0.1674
Trichomonas vaginalis conserved hypothetical protein 0.0956 0.1674 0.2606
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0238 0.0351
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0956 0.1674 0.1674
Echinococcus multilocularis Zinc finger, PHD finger 0.0592 0.1015 0.1015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Onchocerca volvulus 0.0956 0.1674 0.3935
Trichomonas vaginalis PIKK family atypical protein kinase 0.0213 0.0331 0.0498
Leishmania major peptidylprolyl isomerase-like protein 0.0053 0.0043 0.0257
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus tyrosine protein kinase Blk 0.2385 0.4254 0.4254
Brugia malayi Carboxylesterase family protein 0.0084 0.0098 0.0153
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0956 0.1674 0.2608
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0956 0.1674 0.3935
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.0097 0.0151
Schistosoma mansoni hypothetical protein 0.1428 0.2527 0.2527
Brugia malayi hypothetical protein 0.0039 0.0017 0.0027
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0017 0.0027
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0956 0.1674 0.1674
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0956 0.1674 0.2606
Brugia malayi Serotonin receptor 0.0075 0.0082 0.0129
Brugia malayi cytokine inducible SH2-containing protein 5 0.1428 0.2527 0.3958
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni opsin-like receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis SH2 motif 0.1428 0.2527 0.2527
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.5565 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0268 0.0399
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.1428 0.2527 0.2527
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.0209 0.0325 0.0508
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.0082 0.0082
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Brugia malayi hypothetical protein 0.0044 0.0026 0.004
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0084 0.0098 0.0098
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Onchocerca volvulus 0.0075 0.0082 0.0193
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.064 0.1103 0.1709
Echinococcus granulosus G protein coupled receptor 139 0.0075 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0075 0.0082 0.0082
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.2385 0.4254 0.4254
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0017 0.0041
Onchocerca volvulus Tyrosine kinase homolog 0.0956 0.1674 0.3935
Onchocerca volvulus 0.0075 0.0082 0.0193
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0075 0.0082 0.0082
Plasmodium vivax protein kinase, putative 0.0956 0.1674 1
Echinococcus granulosus tyrosine protein kinase 0.0956 0.1674 0.1674
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trypanosoma cruzi UDP-galactopyranose mutase 0.0043 0.0024 0.0015
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.1225 0.2158 0.3366
Schistosoma mansoni cpg binding protein 0.0062 0.0059 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) hypothetical protein 0.0043 0.0024 0.0027
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0062 0.0059 0.0538
Loa Loa (eye worm) variant SH3 domain-containing protein 0.1428 0.2527 0.2853
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.3422 0.6129 0.9599
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) phosphatidylinositol 3 0.0178 0.0268 0.0303
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni steroid hormone receptor ad4bp 0.0083 0.0097 0.0097
Onchocerca volvulus 0.0956 0.1674 0.3935
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0053 0.0043 0.0043
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0607 0.1043 1
Trichomonas vaginalis TK family protein kinase 0.0956 0.1674 0.2606
Onchocerca volvulus 0.0141 0.0202 0.0474
Echinococcus granulosus serotonin receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.0082 0.0082
Echinococcus multilocularis neuropeptide receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0075 0.0082 0.0082
Schistosoma mansoni shc transforming protein 0.1428 0.2527 0.2527
Echinococcus multilocularis 0.0043 0.0024 0.0024
Chlamydia trachomatis protoporphyrinogen oxidase 0.0043 0.0024 0.5
Loa Loa (eye worm) RGC/RGC protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.2385 0.4254 0.4254
Entamoeba histolytica tyrosin kinase, putative 0.0956 0.1674 0.2608
Schistosoma mansoni hypothetical protein 0.0172 0.0257 0.0257
Loa Loa (eye worm) TK/ROR protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis epidermal growth factor receptor 0.1037 0.1819 0.1819
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0083 0.0097 0.0097
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0141 0.0202 0.0202
Trypanosoma cruzi protein kinase, putative 0.0956 0.1674 0.2606
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0053 0.0043 0.0045
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Echinococcus granulosus growth factor receptor bound protein 2 0.1428 0.2527 0.2527
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.0097 0.0151
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.064 0.1103 0.1245
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Brugia malayi Variant SH3 domain containing protein 0.1428 0.2527 0.3958
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Onchocerca volvulus Neuropeptide F receptor homolog 0.0075 0.0082 0.0193
Brugia malayi SH2 domain containing protein 0.2385 0.4254 0.6664
Loa Loa (eye worm) TK/ALK protein kinase 0.0956 0.1674 0.189
Brugia malayi hypothetical protein 0.0039 0.0017 0.0027
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0075 0.0082 0.0082
Echinococcus granulosus geminin 0.0172 0.0257 0.0257
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0067 0.031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0206 0.0319 0.0478
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Schistosoma mansoni neuropeptide receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0039 0.0017 0.0027
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Onchocerca volvulus 0.0075 0.0082 0.0193
Echinococcus granulosus epidermal growth factor receptor 0.1037 0.1819 0.1819
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.2385 0.4254 0.4254
Loa Loa (eye worm) hypothetical protein 0.0153 0.0223 0.0252
Echinococcus multilocularis FL cytokine receptor 0.0956 0.1674 0.1674
Schistosoma mansoni tyrosine kinase 0.1004 0.176 0.176
Leishmania major phosphatidylinositol 3-kinase, putative 0.0592 0.1015 0.6065
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0956 0.1674 0.2622
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0075 0.0082 0.0129
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0269 0.0432 0.258
Schistosoma mansoni tensin 0.1428 0.2527 0.2527
Schistosoma mansoni tyrosine kinase 0.2385 0.4254 0.4254
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1428 0.2527 0.2527
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis SH2 domain containing protein 7 0.1428 0.2527 0.2527
Echinococcus multilocularis tyrosine protein kinase Src64B 0.2385 0.4254 0.4254
Brugia malayi Variant SH3 domain containing protein 0.1428 0.2527 0.3958
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Schistosoma mansoni serine/threonine protein kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0075 0.0082 0.0093
Echinococcus granulosus ephrin type A receptor 4 A 0.0956 0.1674 0.1674
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis 0.0141 0.0202 0.0202
Trichomonas vaginalis PIKK family atypical protein kinase 0.0269 0.0432 0.0656
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.0082 0.0082
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0027 0.0027
Onchocerca volvulus 0.0075 0.0082 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0206 0.0318 0.0478
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.2195 0.3911 0.6127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0214 0.0333 0.05
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.0082 0.0093
Brugia malayi nuclear receptor NHR-88 0.0083 0.0097 0.0151
Echinococcus granulosus 7TM GPCR rhodopsin 0.0075 0.0082 0.0082
Giardia lamblia Kinase 0.0956 0.1674 0.4734
Schistosoma mansoni acetylcholinesterase 0.0084 0.0098 0.0098
Echinococcus multilocularis tyrosine protein kinase Blk 0.2385 0.4254 0.4254
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Loa Loa (eye worm) hypothetical protein 0.0043 0.0024 0.0027
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0043 0.0024 0.0024
Echinococcus granulosus serine protein kinase ATM 0.0158 0.0232 0.0232
Echinococcus multilocularis G-protein coupled receptor, putative 0.0075 0.0082 0.0082
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0241 0.0382 0.228
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0067 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0382 0.0577
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus signal transduction protein lnk realted 0.1428 0.2527 0.2527
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.1428 0.2527 0.2527
Loa Loa (eye worm) hypothetical protein 0.0084 0.0098 0.0111
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Schistosoma mansoni neuropeptide receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.064 0.1103 0.1709
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0522 0.089 0.089
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0083 0.0097 0.0151
Loa Loa (eye worm) phosphatidylinositol 3 0.0141 0.0202 0.0228
Toxoplasma gondii HEAT repeat-containing protein 0.003 0 0.0003
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.1428 0.2527 0.5939
Echinococcus multilocularis protein kinase 0.0956 0.1674 0.1674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0249 0.0396 0.0599
Trichomonas vaginalis conserved hypothetical protein 0.0956 0.1674 0.2606
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0141 0.0202 0.0294
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Brugia malayi Carboxylesterase family protein 0.0084 0.0098 0.0153
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Onchocerca volvulus 0.2385 0.4254 1
Brugia malayi hypothetical protein 0.2385 0.4254 0.6664
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.1428 0.2527 0.2527
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0956 0.1674 0.189
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Leishmania major hypothetical protein, conserved 0.0956 0.1674 1
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Brugia malayi Importin beta-1 subunit 0.003 0 0.0001
Echinococcus granulosus snurportin 1 0.032 0.0524 0.0524
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0014 0.0014
Mycobacterium ulcerans monoamine oxidase 0.0043 0.0024 0.0093
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus c src tyrosine kinase 0.2385 0.4254 0.4254
Echinococcus multilocularis tyrosine protein kinase Src42A 0.2385 0.4254 0.4254
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0016 0.0016
Mycobacterium tuberculosis Possible oxidoreductase 0.0043 0.0024 0.0174
Plasmodium vivax tyrosine kinase-like protein, putative 0.0956 0.1674 1
Onchocerca volvulus 0.0153 0.0223 0.0525
Loa Loa (eye worm) carboxylesterase 0.0084 0.0098 0.0111
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Brugia malayi Protein kinase domain containing protein 0.2385 0.4254 0.6664
Plasmodium falciparum protein kinase, putative 0.0956 0.1674 1
Mycobacterium tuberculosis Carboxylesterase LipT 0.0084 0.0098 0.0948
Schistosoma mansoni serine/threonine protein kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0043 0.0045
Schistosoma mansoni inositol monophosphatase 0.0037 0.0014 0.0014
Echinococcus granulosus tm gpcr rhodopsin 0.06 0.1031 0.1031
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0956 0.1674 0.1674
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1225 0.2158 0.3368
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0269 0.0432 0.0432
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0062 0.0059 0.0059
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1674 0.189
Brugia malayi tailless protein 0.0039 0.0017 0.0027
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0075 0.0082 0.0129
Toxoplasma gondii protein kinase 0.0956 0.1674 1
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0178 0.0268 0.1241
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0956 0.1674 0.2606
Trichomonas vaginalis conserved hypothetical protein 0.0956 0.1674 0.2606
Schistosoma mansoni ephrin receptor 0.0956 0.1674 0.1674
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.0097 0.0097
Onchocerca volvulus 0.0084 0.0098 0.023
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis FTZ F1 alpha 0.0083 0.0097 0.0097
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis neuropeptide s receptor 0.0075 0.0082 0.0082
Echinococcus granulosus tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Schistosoma mansoni neuroligin 3 (S09 family) 0.0084 0.0098 0.0098
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0956 0.1674 0.2622
Onchocerca volvulus 0.0075 0.0082 0.0193
Echinococcus granulosus somatostatin receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0017 0.0017
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0067 0.0403
Echinococcus multilocularis carbonic anhydrase II 0.0124 0.017 0.017
Schistosoma mansoni immunophilin 0.0053 0.0043 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0083 0.0097 0.0109
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Brugia malayi integrin-linked kinase 0.0956 0.1674 0.2622
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis SH2 domain containing adapter protein F 0.1428 0.2527 0.2527
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0172 0.0172
Schistosoma mansoni opsin-like receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0268 0.0399
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) TK protein kinase 0.2385 0.4254 0.4804
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0084 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Loa Loa (eye worm) phosphatidylinositol 3 0.0141 0.0202 0.0228
Echinococcus multilocularis serine protein kinase ATM 0.0158 0.0232 0.0232
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.2593 0.4631 0.7248
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.2195 0.3911 0.3911
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.2385 0.4254 0.4254
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0084 0.0098 0.0111
Onchocerca volvulus 0.0956 0.1674 0.3935
Onchocerca volvulus 0.1428 0.2527 0.5939
Echinococcus multilocularis somatostatin receptor 0.0075 0.0082 0.0082
Echinococcus granulosus acetylcholinesterase 0.0496 0.0843 0.0843
Brugia malayi Melatonin receptor type 1A 0.0075 0.0082 0.0129
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.06 0.1031 0.1031
Schistosoma mansoni opsin-like receptor 0.0075 0.0082 0.0082
Mycobacterium leprae conserved hypothetical protein 0.0141 0.0202 1
Brugia malayi follicle stimulating hormone receptor 0.0075 0.0082 0.0129
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0046 0.003 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0206 0.0319 0.0478
Echinococcus multilocularis acetylcholinesterase 0.0496 0.0843 0.0843
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Echinococcus multilocularis expressed protein 0.0379 0.0631 0.0631
Trypanosoma brucei carbonic anhydrase-like protein 0.0124 0.017 0.0785
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0369 0.0557
Echinococcus granulosus suppressor of cytokine signaling 6 0.1428 0.2527 0.2527
Echinococcus granulosus sex peptide receptor 0.0075 0.0082 0.0082
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0043 0.0024 0.0024
Echinococcus multilocularis dnaJ subfamily B 0.0415 0.0696 0.0696
Echinococcus multilocularis serotonin transporter 0.0153 0.0223 0.0223
Loa Loa (eye worm) sex muscle abnormal protein 5 0.1428 0.2527 0.2853
Trichomonas vaginalis immunophilin, putative 0.0053 0.0043 0.0045
Entamoeba histolytica hypothetical protein 0.0141 0.0202 0.0297
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2385 0.4254 0.4254
Echinococcus granulosus tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.0082 0.0082
Loa Loa (eye worm) SH2 domain-containing protein 0.1428 0.2527 0.2853
Plasmodium vivax hypothetical protein, conserved 0.0141 0.0202 0.1204
Brugia malayi ORL1-like opioid receptor 0.0075 0.0082 0.0129
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.0082 0.0093
Toxoplasma gondii STE kinase 0.0956 0.1674 1
Schistosoma mansoni retinoic acid receptor RXR 0.0083 0.0097 0.0097
Echinococcus multilocularis fk506 binding protein 0.0053 0.0043 0.0043
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0083 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0209 0.0325 0.0367
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0084 0.0098 0.0948
Brugia malayi Raf kinase 0.0956 0.1674 0.2622
Loa Loa (eye worm) hypothetical protein 0.0158 0.0232 0.0262
Loa Loa (eye worm) phosphatidylinositol 3 0.4932 0.8857 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0269 0.0432 0.0656
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0269 0.0432 0.1999
Onchocerca volvulus 0.0956 0.1674 0.3935
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0083 0.0097 0.0151
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Entamoeba histolytica hypothetical protein 0.0141 0.0202 0.0297
Brugia malayi neuropeptide F receptor 0.0075 0.0082 0.0129
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0083 0.0097 0.0097
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus insulin receptor 0.1004 0.176 0.176
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Echinococcus granulosus raf serine:threonine protein kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis neuropeptide FF receptor 2 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0053 0.0043 0.0043
Brugia malayi nuclear hormone receptor family member odr-7 0.0039 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Echinococcus granulosus protein tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus granulosus activated cdc42 kinase 1 0.0956 0.1674 0.1674
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0178 0.0268 0.042
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Leishmania major phosphatidylinositol kinase, putative 0.0141 0.0202 0.1204
Echinococcus granulosus tyrosine protein kinase csk 0.0956 0.1674 0.1674
Brugia malayi hypothetical protein 0.0084 0.0098 0.0153
Schistosoma mansoni neuropeptide receptor 0.0075 0.0082 0.0082
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0044 0.0026 0.0026
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0043 0.0024 0.0141
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1225 0.2158 1
Brugia malayi Inositol-1 0.0037 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0956 0.1674 0.1674
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0053 0.0043 0.0281
Brugia malayi nuclear receptor NHR-67 0.0039 0.0017 0.0027
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0084 0.0098 0.0098
Schistosoma mansoni RAR-like nuclear receptor 0.0083 0.0097 0.0097
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0124 0.017 0.0266
Echinococcus granulosus neuropeptide receptor 0.0075 0.0082 0.0082
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Brugia malayi Variant SH3 domain containing protein 0.1428 0.2527 0.3958
Echinococcus multilocularis fmrfamide receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis protoporphyrinogen oxidase 0.0043 0.0024 0.0024
Echinococcus granulosus tyrosine protein kinase ABL1 0.2385 0.4254 0.4254
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0141 0.0202 0.0294
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0189 0.0288 0.1332
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0048 0.0048
Trypanosoma cruzi protein kinase, putative 0.0956 0.1674 0.2606
Echinococcus multilocularis g-protein coupled receptor 0.0075 0.0082 0.0082
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0039 0.0017 0.0017
Echinococcus granulosus suppressor of cytokine signaling 7 0.1428 0.2527 0.2527
Echinococcus granulosus expressed conserved protein 0.1428 0.2527 0.2527
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.1083 0.1903 0.2966
Echinococcus granulosus thyroid hormone receptor alpha 0.0039 0.0017 0.0017
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0956 0.1674 0.1674
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus granulosus dro:myosuppressin receptor 0.0075 0.0082 0.0082
Brugia malayi steroid hormone receptor 0.0083 0.0097 0.0151
Echinococcus multilocularis dro:myosuppressin receptor 0.0075 0.0082 0.0082
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0178 0.0268 0.0399
Brugia malayi Tachykinin-like peptides receptor 99D 0.0075 0.0082 0.0129
Loa Loa (eye worm) TK/CSK protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni biogenic amine (5HT) receptor 0.0075 0.0082 0.0082
Brugia malayi Receptor family ligand binding region containing protein 0.0956 0.1674 0.2622
Echinococcus granulosus BC026374 protein S09 family 0.0084 0.0098 0.0098
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Echinococcus granulosus tyrosine protein kinase pr2 0.0956 0.1674 0.1674
Echinococcus multilocularis BC026374 protein (S09 family) 0.0084 0.0098 0.0098
Treponema pallidum sodium- and chloride- dependent transporter 0.0153 0.0223 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0369 0.0557
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0075 0.0082 0.0093
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus multilocularis SH2 motif 0.1428 0.2527 0.2527
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Schistosoma mansoni inositol monophosphatase 0.0037 0.0014 0.0014
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0382 0.0577
Echinococcus granulosus tyrosine protein kinase shark 0.2385 0.4254 0.4254
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0141 0.0202 0.0294
Onchocerca volvulus 0.0075 0.0082 0.0193
Echinococcus granulosus tyrosine protein kinase Src64B 0.2385 0.4254 0.4254
Entamoeba histolytica SH2-protein kinase domain containing protein 0.2385 0.4254 0.6658
Echinococcus granulosus lysine specific histone demethylase 1A 0.0043 0.0024 0.0024
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0124 0.017 0.0192
Echinococcus multilocularis tensin 0.1428 0.2527 0.2527
Loa Loa (eye worm) hypothetical protein 0.0049 0.0034 0.0038
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Echinococcus multilocularis acetylcholinesterase 0.0496 0.0843 0.0843
Schistosoma mansoni tyrosine kinase 0.1107 0.1946 0.1946
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0039 0.0017 0.0017
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Echinococcus multilocularis natriuretic peptide receptor 1 0.0956 0.1674 0.1674
Echinococcus multilocularis NCK adaptor protein 0.1428 0.2527 0.2527
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.3564 0.6384 1
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.019 0.0289 0.1728
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0956 0.1674 0.1674
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni hypothetical protein 0.1428 0.2527 0.2527
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi amine oxidase, flavin-containing family protein 0.0043 0.0024 0.0037
Onchocerca volvulus 0.0075 0.0082 0.0193
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1037 0.1819 0.1819
Echinococcus granulosus biogenic amine 5HT receptor 0.0075 0.0082 0.0082
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0075 0.0082 0.0082
Onchocerca volvulus 0.1428 0.2527 0.5939
Loa Loa (eye worm) TK/ACK protein kinase 0.0956 0.1674 0.189
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0026 0.0026
Schistosoma mansoni thyroid hormone receptor 0.0355 0.0588 0.0588
Echinococcus granulosus tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Echinococcus multilocularis tyrosine protein kinase Abl 0.2385 0.4254 0.4254
Echinococcus multilocularis suppressor of cytokine signaling 6 0.1428 0.2527 0.2527
Schistosoma mansoni adapter molecule crk 0.1428 0.2527 0.2527
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) TK/FAK protein kinase 0.0956 0.1674 0.189
Brugia malayi Tyrosine-protein kinase PR2 0.0956 0.1674 0.2622
Echinococcus multilocularis tyrosine protein kinase shark 0.2385 0.4254 0.4254
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0014 0.0014
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0956 0.1674 0.1674
Brugia malayi SRC-1 0.2385 0.4254 0.6664
Echinococcus multilocularis tyrosine protein kinase csk 0.0956 0.1674 0.1674
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0012 0.0012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0027 0.0027
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0141 0.0202 0.1204
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.0492 0.0836 0.0836
Brugia malayi Immunoglobulin I-set domain containing protein 0.0956 0.1674 0.2622
Echinococcus multilocularis heat shock protein 70 0.0956 0.1674 0.1674
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Trichomonas vaginalis spcc417.12 protein, putative 0.0084 0.0098 0.0132
Brugia malayi SH2 domain containing protein 0.2385 0.4254 0.6664
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0178 0.0268 0.0268
Echinococcus granulosus neuropeptide s receptor 0.0075 0.0082 0.0082
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0014 0.0063
Schistosoma mansoni adenoreceptor 0.0075 0.0082 0.0082
Echinococcus multilocularis allatostatin A receptor 0.0075 0.0082 0.0082
Schistosoma mansoni amine oxidase 0.0043 0.0024 0.0024
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0083 0.0097 0.0109
Echinococcus granulosus alpha 1A adrenergic receptor 0.0075 0.0082 0.0082
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.0082 0.0082
Echinococcus granulosus serotonin transporter 0.0153 0.0223 0.0223
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0956 0.1674 0.1674
Leishmania major protein kinase, putative 0.0956 0.1674 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Echinococcus granulosus tensin 0.1428 0.2527 0.2527
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.3564 0.6384 1
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.064 0.1103 0.1712
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.1428 0.2527 0.2527
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.064 0.1103 0.6589
Plasmodium falciparum tyrosine kinase-like protein 0.0956 0.1674 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis 0.0047 0.0031 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0956 0.1674 0.2606
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0956 0.1674 0.1674
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0053 0.0043 0.0048
Brugia malayi nuclear hormone receptor family member nhr-6 0.0039 0.0017 0.0027
Onchocerca volvulus 0.0075 0.0082 0.0193
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0044 0.0026 0.0026
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0161 0.0238 0.1419
Mycobacterium tuberculosis Conserved hypothetical protein 0.0141 0.0202 0.2029
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Schistosoma mansoni amine GPCR 0.0075 0.0082 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0206 0.0318 0.0478
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0075 0.0082 0.0082
Schistosoma mansoni amine GPCR 0.0075 0.0082 0.0082
Echinococcus multilocularis fmrfamide receptor 0.0075 0.0082 0.0082
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0075 0.0082 0.0193
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0956 0.1674 0.2622
Brugia malayi putative neuropeptide receptor 0.0075 0.0082 0.0129
Brugia malayi hypothetical protein 0.1428 0.2527 0.3958
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0269 0.0432 0.258
Plasmodium vivax importin-beta 2, putative 0.003 0 0.0003
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0141 0.0202 0.0202
Echinococcus granulosus g protein coupled receptor 0.0075 0.0082 0.0082
Echinococcus granulosus retinal guanylyl cyclase 2 0.0956 0.1674 0.1674
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Brugia malayi SH2 domain containing protein 0.1428 0.2527 0.3958
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Loa Loa (eye worm) hypothetical protein 0.0084 0.0098 0.0111
Echinococcus multilocularis ephrin type A receptor 4 A 0.0956 0.1674 0.1674
Echinococcus granulosus retinal guanylyl cyclase 2 0.0956 0.1674 0.1674
Echinococcus multilocularis suppressor of cytokine signaling 7 0.1428 0.2527 0.2527
Loa Loa (eye worm) TK/Met protein kinase 0.0956 0.1674 0.189
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0053 0.0043 0.0043
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0956 0.1674 0.1674
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0178 0.0268 0.1603
Schistosoma mansoni biogenic amine receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis carboxylesterase 5A 0.0496 0.0843 0.0843
Loa Loa (eye worm) SH2 domain-containing protein 0.1428 0.2527 0.2853
Entamoeba histolytica receptor protein kinase, putative 0.0956 0.1674 0.2608
Brugia malayi conserved hypotetical protein 0.0039 0.0017 0.0027
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1225 0.2158 0.3368
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0075 0.0082 0.0129
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0083 0.0097 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0206 0.0319 0.0478
Schistosoma mansoni hypothetical protein 0.032 0.0524 0.0524
Loa Loa (eye worm) hypothetical protein 0.2195 0.3911 0.4416
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0607 0.1043 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0956 0.1674 0.2608
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0269 0.0432 0.0432
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0084 0.0098 0.0948
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0158 0.0232 0.0232
Entamoeba histolytica protein kinase rad3, putative 0.0158 0.0232 0.0345
Echinococcus multilocularis growth factor receptor bound protein 2 0.1428 0.2527 0.2527
Brugia malayi Sex muscle abnormal protein 5 0.1428 0.2527 0.3958
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.0082 0.0082
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Echinococcus granulosus neuropeptide receptor 0.0075 0.0082 0.0082
Brugia malayi CXXC zinc finger family protein 0.0059 0.0053 0.0083
Loa Loa (eye worm) phosphatidylinositol 3 0.0141 0.0202 0.0228
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0014 0.0084
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0141 0.0202 0.0316
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.0082 0.0082
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.3564 0.6384 1
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Loa Loa (eye worm) phosphatidylinositol kinase 0.0141 0.0202 0.0228
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.2385 0.4254 0.4254
Brugia malayi hypothetical protein 0.0956 0.1674 0.2622
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1225 0.2158 0.3381
Onchocerca volvulus 0.0075 0.0082 0.0193
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0043 0.0024 0.0024
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0027 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni vav2 0.1428 0.2527 0.2527
Schistosoma mansoni hypothetical protein 0.0956 0.1674 0.1674
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0956 0.1674 0.1674
Schistosoma mansoni hypothetical protein 0.0522 0.089 0.089
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0017 0.0041
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Onchocerca volvulus 0.0059 0.0053 0.0124
Schistosoma mansoni tensin 0.1428 0.2527 0.2527
Trichomonas vaginalis PIKK family atypical protein kinase 0.0214 0.0333 0.05
Mycobacterium tuberculosis Conserved hypothetical protein 0.0043 0.0024 0.0174
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0956 0.1674 0.1674
Echinococcus granulosus integrin linked protein kinase 0.0956 0.1674 0.1674
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Brugia malayi Protein-tyrosine phosphatase containing protein 0.1428 0.2527 0.3958
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.3564 0.6384 1
Brugia malayi Protein kinase domain containing protein 0.2385 0.4254 0.6664
Leishmania major phosphatidylinositol 3-kinase, putative 0.0178 0.0268 0.1603
Loa Loa (eye worm) acetylcholinesterase 1 0.0496 0.0843 0.0952
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0027 0.0027
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Onchocerca volvulus 0.1428 0.2527 0.5939
Echinococcus multilocularis tyrosine protein kinase csk 0.0956 0.1674 0.1674
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.064 0.1103 0.5109
Echinococcus granulosus kinase suppressor of Ras 1 0.0956 0.1674 0.1674
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Echinococcus granulosus 7tm_1 domain containing protein 0.0075 0.0082 0.0082
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.1225 0.2158 0.3366
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0044 0.005
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis epidermal growth factor receptor 0.1107 0.1946 0.1946
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0956 0.1674 0.1674
Trichomonas vaginalis STE family protein kinase 0.0956 0.1674 0.2606
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0083 0.0097 0.0151
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Onchocerca volvulus Bile acid receptor homolog 0.0083 0.0097 0.0227
Echinococcus multilocularis neuroligin 0.0084 0.0098 0.0098
Loa Loa (eye worm) phosphatidylinositol 3 0.0141 0.0202 0.0228
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.0082 0.0082
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0012 0.0012
Entamoeba histolytica serine/threonine kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0956 0.1674 0.189
Toxoplasma gondii histone lysine-specific demethylase 0.0043 0.0024 0.0141
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0053 0.0043 0.0045
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.3564 0.6384 1
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0043 0.0024 0.0093
Echinococcus granulosus protein kinase 0.0956 0.1674 0.1674
Brugia malayi hypothetical protein 0.0044 0.0026 0.004

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 2.81 uM Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay ChEMBL. 23685571

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 23685571

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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