Detailed information for compound 1821302

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 328.405 | Formula: C19H24N2O3
  • H donors: 2 H acceptors: 2 LogP: 3.18 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C(=O)NC1C2CC3CC1CC(C2)C3)NOCc1ccccc1
  • InChi: 1S/C19H24N2O3/c22-18(19(23)21-24-11-12-4-2-1-3-5-12)20-17-15-7-13-6-14(9-15)10-16(17)8-13/h1-5,13-17H,6-11H2,(H,20,22)(H,21,23)
  • InChiKey: KGPGVLQFAZZODB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens epoxide hydrolase 2, cytoplasmic Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium ulcerans epoxide hydrolase EphA Get druggable targets OG5_129061 All targets in OG5_129061
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) Get druggable targets OG5_129061 All targets in OG5_129061
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0193 0.0797 0.0795
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0589 0.2772 0.2771
Trypanosoma brucei beta tubulin 0.025 0.108 0.808
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.004 0.0035 0.031
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0589 0.2772 0.6423
Trypanosoma cruzi trypanothione reductase, putative 0.0063 0.0148 0.1354
Echinococcus granulosus transcription factor Dp 1 0.0041 0.004 0.0087
Schistosoma mansoni CD36-like class B scavenger receptor 0.0041 0.004 0.0038
Echinococcus granulosus alpha 1A adrenergic receptor 0.0589 0.2772 0.6423
Leishmania major hypothetical protein, conserved 0.0034 0.0003 0.0012
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.005 0.0081 0.0079
Echinococcus granulosus lysosome membrane protein 2 0.0041 0.004 0.0088
Plasmodium falciparum plasmepsin VII 0.0046 0.0062 0.0542
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0189 0.1737
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0156 0.0611 0.0609
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0589 0.2772 0.3014
Onchocerca volvulus 0.0589 0.2772 1
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Echinococcus granulosus neuropeptides capa receptor 0.0589 0.2772 0.6423
Mycobacterium leprae Possible thiamine biosynthesis oxidoreductase ThiO 0.017 0.0681 0.0679
Echinococcus granulosus 7tm_1 domain containing protein 0.0589 0.2772 0.6423
Echinococcus multilocularis beta tubulin 0.025 0.108 0.2499
Trypanosoma brucei heat shock protein, putative 0.0141 0.0538 0.4023
Leishmania major hypothetical protein, conserved 0.0034 0.0003 0.0012
Onchocerca volvulus 0.0589 0.2772 1
Echinococcus granulosus sex peptide receptor 0.0589 0.2772 0.6423
Trypanosoma brucei heat shock protein, putative 0.0141 0.0538 0.4023
Loa Loa (eye worm) hypothetical protein 0.0046 0.0062 0.006
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0034 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0135 0.0508 0.0506
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.004 0.0035 0.0033
Brugia malayi beta-tubulin, identical 0.025 0.108 0.1173
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.0551 0.0549
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0063 0.0148 0.0159
Toxoplasma gondii thioredoxin reductase 0.0063 0.0148 0.1354
Echinococcus granulosus protein prenyltransferase alpha subunit 0.004 0.0035 0.0077
Trichomonas vaginalis glucosylceramidase, putative 0.0279 0.1224 1
Loa Loa (eye worm) tubulin beta chain 0.025 0.108 0.1078
Echinococcus granulosus neuropeptide receptor 0.0694 0.3294 0.7633
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.004 0.0035 0.0265
Trypanosoma brucei DNA polymerase IV, putative 0.0083 0.0245 0.1836
Echinococcus multilocularis g-protein coupled receptor 0.0589 0.2772 0.6423
Loa Loa (eye worm) glycerol-3-phosphate dehydrogenase 0.017 0.0681 0.0679
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0096 0.031 0.0308
Loa Loa (eye worm) hypothetical protein 0.0041 0.004 0.0038
Trichomonas vaginalis tubulin gamma chain, putative 0.025 0.108 0.8787
Trichomonas vaginalis glucosylceramidase, putative 0.0279 0.1224 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0589 0.2772 0.6423
Echinococcus multilocularis neuropeptide Y receptor 0.0589 0.2772 0.6423
Loa Loa (eye worm) hypothetical protein 0.017 0.0681 0.0679
Trypanosoma brucei RNA helicase, putative 0.0301 0.1336 1
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.004 0.0035 0.0265
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0096 0.031 0.0714
Plasmodium vivax heat shock protein 86, putative 0.0141 0.0538 0.4808
Brugia malayi aspartic protease BmAsp-2, identical 0.0046 0.0062 0.0065
Schistosoma mansoni integrin alpha-ps 0.0077 0.0217 0.0215
Trypanosoma cruzi DNA polymerase kappa, putative 0.0083 0.0245 0.2258
Echinococcus multilocularis zinc finger protein Ran binding 0.0034 0.0003 0.0003
Trypanosoma brucei heat shock protein, putative 0.0141 0.0538 0.4023
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0057 0.0119 0.0127
Brugia malayi hypothetical protein 0.0046 0.0062 0.0065
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0589 0.2772 0.2771
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.0551 0.1272
Trichomonas vaginalis heat shock protein, putative 0.0128 0.0471 0.3673
Loa Loa (eye worm) G-protein coupled receptor 0.0589 0.2772 0.2771
Brugia malayi neuropeptide F receptor 0.0589 0.2772 0.3014
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0589 0.2772 0.2771
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Loa Loa (eye worm) aspartyl protease 6 0.0046 0.0062 0.006
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.1059 0.511 0.5109
Echinococcus granulosus rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0096 0.031 0.285
Brugia malayi G protein-coupled receptor F59B2.13 0.0589 0.2772 0.3014
Leishmania major hypothetical protein, conserved 0.0034 0.0003 0.0012
Onchocerca volvulus 0.004 0.0035 0.0116
Schistosoma mansoni heat shock protein 0.0141 0.0538 0.0536
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0279 0.1224 0.133
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0589 0.2772 0.2771
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0034 0.0002 0.0015
Echinococcus granulosus integrin alpha ps 0.0037 0.0018 0.0036
Echinococcus granulosus tm gpcr rhodopsin 0.0589 0.2772 0.6423
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0589 0.2772 0.6423
Plasmodium falciparum plasmepsin II 0.0193 0.0797 0.7375
Echinococcus multilocularis membrane associated guanylate kinase ww and pdz 0.005 0.0081 0.0184
Trypanosoma cruzi heat shock protein 85, putative 0.0141 0.0538 0.4969
Echinococcus granulosus adenylate cyclase type IX 0.0085 0.0256 0.059
Plasmodium falciparum plasmepsin IV 0.0193 0.0797 0.7375
Brugia malayi hypothetical protein 0.0041 0.004 0.0041
Leishmania major beta tubulin 0.025 0.108 1
Schistosoma mansoni hypothetical protein 0.0301 0.1336 0.1335
Echinococcus granulosus G protein coupled receptor 139 0.0589 0.2772 0.6423
Echinococcus granulosus dna polymerase kappa 0.0083 0.0245 0.0564
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0046 0.0062 0.006
Schistosoma mansoni neuropeptide F-like receptor 0.0589 0.2772 0.2771
Loa Loa (eye worm) MH2 domain-containing protein 0.0129 0.0478 0.0476
Echinococcus granulosus neuropeptide Y receptor 0.0589 0.2772 0.6423
Schistosoma mansoni fad oxidoreductase 0.017 0.0681 0.0679
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 20 0.017 0.0681 0.6302
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0193 0.0797 0.7378
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Brugia malayi Adenylyl cyclase protein 0.0135 0.0508 0.0551
Echinococcus multilocularis adenylate cyclase 9 0.0135 0.0508 0.1174
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Loa Loa (eye worm) tubulin beta-1 chain 0.025 0.108 0.1078
Trypanosoma cruzi WLM domain containing protein, putative 0.0034 0.0003 0.0012
Brugia malayi G-protein coupled receptor 0.0589 0.2772 0.3014
Loa Loa (eye worm) BEN-1 protein 0.025 0.108 0.1078
Brugia malayi hypothetical protein 0.0589 0.2772 0.3014
Brugia malayi Tachykinin-like peptides receptor 99D 0.0589 0.2772 0.3014
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0034 0.0003 0.0012
Schistosoma mansoni neuropeptide receptor 0.0589 0.2772 0.2771
Brugia malayi hypothetical protein 0.0589 0.2772 0.3014
Leishmania major glycerol-3-phosphate dehydrogenase-like protein 0.017 0.0681 0.6302
Echinococcus multilocularis sex peptide receptor 0.0589 0.2772 0.6423
Mycobacterium ulcerans DNA polymerase IV 0.0083 0.0245 0.0243
Toxoplasma gondii ran binding protein 0.0034 0.0003 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0245 0.1836
Loa Loa (eye worm) thioredoxin reductase 0.0063 0.0148 0.0146
Echinococcus multilocularis membrane associated guanylate kinase, WW and PDZ 0.005 0.0081 0.0184
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.004 0.0035 0.031
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Leishmania major hypothetical protein, conserved 0.0034 0.0003 0.0012
Plasmodium falciparum plasmepsin VIII, putative 0.0046 0.0062 0.0542
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0046 0.0062 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0245 0.1836
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0045 0.0047
Onchocerca volvulus 0.013 0.048 0.172
Echinococcus granulosus Tubulin beta 2C chain 0.025 0.108 0.2499
Plasmodium falciparum FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.017 0.0681 0.6298
Loa Loa (eye worm) hypothetical protein 0.0034 0.0003 0.0001
Brugia malayi hypothetical protein 0.0589 0.2772 0.3014
Schistosoma mansoni hypothetical protein 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Echinococcus granulosus allatostatin A receptor 0.0589 0.2772 0.6423
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Entamoeba histolytica heat shock protein 90, putative 0.0141 0.0538 0.4849
Leishmania major beta tubulin 0.025 0.108 1
Echinococcus granulosus neuropeptides capa receptor 0.0589 0.2772 0.6423
Echinococcus granulosus beta tubulin 0.025 0.108 0.2499
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.0189 0.0187
Leishmania major hypothetical protein, conserved 0.017 0.0681 0.6302
Brugia malayi larval opioid receptor 0.0589 0.2772 0.3014
Plasmodium vivax tubulin beta chain, putative 0.025 0.108 1
Loa Loa (eye worm) BEN-1 protein 0.025 0.108 0.1078
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Echinococcus granulosus tm gpcr rhodopsin 0.0589 0.2772 0.6423
Trichomonas vaginalis heat shock protein, putative 0.0141 0.0538 0.4231
Trichomonas vaginalis heat shock protein, putative 0.0128 0.0471 0.3673
Schistosoma mansoni amine GPCR 0.0589 0.2772 0.2771
Plasmodium falciparum glutathione reductase 0.0063 0.0148 0.1344
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0589 0.2772 1
Leishmania major trypanothione reductase 0.0063 0.0148 0.1354
Giardia lamblia Beta tubulin 0.025 0.108 1
Echinococcus multilocularis FAD dependent oxidoreductase domain containing protein 0.017 0.0681 0.1575
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.0189 0.1737
Trypanosoma cruzi WLM domain containing protein, putative 0.0034 0.0003 0.0012
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0716 0.3401 0.7881
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Brugia malayi hypothetical protein 0.0589 0.2772 0.3014
Brugia malayi Eukaryotic aspartyl protease family protein 0.0046 0.0062 0.0065
Leishmania major beta tubulin 0.025 0.108 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0899 0.4315 1
Schistosoma mansoni neuropeptide receptor 0.0694 0.3294 0.3293
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.004 0.0035 0.0077
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Echinococcus granulosus somatostatin receptor 0.0589 0.2772 0.6423
Brugia malayi Serotonin receptor 0.0589 0.2772 0.3014
Loa Loa (eye worm) hypothetical protein 0.004 0.0033 0.0031
Schistosoma mansoni neuropeptide f receptor 76f 0.0589 0.2772 0.2771
Schistosoma mansoni glycerol-3-phosphate dehydrogenase 0.017 0.0681 0.0679
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0027 0.0221
Brugia malayi Integrin alpha cytoplasmic region family protein 0.013 0.0481 0.0521
Loa Loa (eye worm) beta-tubulin 0.025 0.108 0.1078
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0197 0.0818 0.0891
Onchocerca volvulus 0.0589 0.2772 1
Schistosoma mansoni brg-1 associated factor 0.0096 0.031 0.0308
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0034 0.0003 0.0012
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0096 0.031 0.0714
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Trypanosoma brucei beta tubulin 0.025 0.108 0.808
Brugia malayi follicle stimulating hormone receptor 0.0589 0.2772 0.3014
Loa Loa (eye worm) hypothetical protein 0.0034 0.0003 0.0001
Schistosoma mansoni tubulin subunit beta 0.025 0.108 0.1078
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0589 0.2772 0.2771
Echinococcus granulosus integrin alpha ps 0.0077 0.0217 0.0499
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Schistosoma mansoni serine-type protease inhibitor 0.0441 0.203 0.2029
Brugia malayi Dopamine receptor protein 2 0.0589 0.2772 0.3014
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0589 0.2772 0.6423
Schistosoma mansoni amine GPCR 0.0589 0.2772 0.2771
Onchocerca volvulus Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial homolog 0.017 0.0681 0.2449
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0193 0.0797 0.1844
Trypanosoma cruzi heat shock protein 85, putative 0.0128 0.0471 0.4353
Loa Loa (eye worm) hypothetical protein 0.0135 0.0505 0.0503
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0589 0.2772 0.2771
Brugia malayi RE18450p 0.017 0.0681 0.0739
Echinococcus multilocularis integrin alpha ps 0.0077 0.0217 0.0499
Toxoplasma gondii beta tubulin 0.025 0.108 1
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.004 0.0035 0.0299
Schistosoma mansoni CD36-like class B scavenger receptor 0.0041 0.004 0.0038
Mycobacterium tuberculosis Probable D-amino acid oxidase Aao 0.187 0.9153 1
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Echinococcus multilocularis Tubulin beta 2C chain 0.025 0.108 0.2499
Schistosoma mansoni amine GPCR 0.0589 0.2772 0.2771
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0045 0.0396
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0046 0.0062 0.006
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Echinococcus multilocularis integrin alpha ps 0.0077 0.0217 0.0499
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0589 0.2772 0.2771
Schistosoma mansoni biogenic amine receptor 0.0589 0.2772 0.2771
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0589 0.2772 0.6423
Schistosoma mansoni hypothetical protein 0.0057 0.0119 0.0117
Plasmodium falciparum tubulin beta chain 0.025 0.108 1
Brugia malayi AKH receptor 0.0589 0.2772 0.3014
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0245 0.1836
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Leishmania major beta tubulin 0.025 0.108 1
Echinococcus granulosus membrane associated guanylate kinase, WW and PDZ 0.005 0.0081 0.0184
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0589 0.2772 0.6423
Leishmania major beta tubulin 0.025 0.108 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0189 0.1737
Schistosoma mansoni tubulin subunit beta 0.025 0.108 0.1078
Trichomonas vaginalis glucosylceramidase, putative 0.0279 0.1224 1
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0375 0.1703 0.6139
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0589 0.2772 0.2771
Echinococcus granulosus integrin alpha 3 0.0132 0.0489 0.113
Loa Loa (eye worm) hypothetical protein 0.0041 0.004 0.0038
Echinococcus multilocularis neuropeptide receptor 0.0589 0.2772 0.6423
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0034 0.0003 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0003 0.0024
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0034 0.0003 0.0001
Echinococcus granulosus neuropeptide Y receptor 0.0589 0.2772 0.6423
Entamoeba histolytica heat shock protein 90, putative 0.0141 0.0538 0.4849
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Echinococcus multilocularis neuropeptide receptor 0.0694 0.3294 0.7633
Plasmodium vivax hypothetical protein, conserved 0.0096 0.031 0.263
Loa Loa (eye worm) hypothetical protein 0.0095 0.0306 0.0304
Echinococcus granulosus CD36 class B scavenger receptor 0.0041 0.004 0.0088
Schistosoma mansoni adenoreceptor 0.0589 0.2772 0.2771
Schistosoma mansoni RNA binding protein 0.0034 0.0003 0.0001
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0116 0.041 0.3157
Echinococcus multilocularis Tubulin beta 2C chain 0.025 0.108 0.2499
Brugia malayi Calcitonin receptor-like protein seb-1 0.1565 0.7634 0.8304
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0746 0.5983
Loa Loa (eye worm) brahma associated protein 0.0096 0.031 0.0308
Onchocerca volvulus 0.0589 0.2772 1
Echinococcus multilocularis integrin alpha 3 0.0132 0.0489 0.113
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Toxoplasma gondii aspartyl protease ASP3 0.0046 0.0062 0.0553
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.004 0.0035 0.0265
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1878 0.9192 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0589 0.2772 0.6423
Echinococcus granulosus rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Trypanosoma brucei Heat shock protein 83, putative 0.0141 0.0538 0.4023
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0589 0.2772 0.6423
Loa Loa (eye worm) hypothetical protein 0.0037 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Schistosoma mansoni hypothetical protein 0.0037 0.0018 0.0016
Leishmania major protein farnesyltransferase alpha subunit, putative 0.004 0.0035 0.031
Entamoeba histolytica tubulin family protein 0.025 0.108 1
Onchocerca volvulus Putative fad oxidoreductase 0.017 0.0681 0.2449
Echinococcus granulosus tm gpcr rhodopsin 0.0589 0.2772 0.6423
Giardia lamblia Beta tubulin 0.025 0.108 1
Plasmodium falciparum plasmepsin VI 0.0193 0.0797 0.7375
Echinococcus multilocularis beta tubulin 0.025 0.108 0.2499
Echinococcus multilocularis neuropeptide Y receptor 0.0589 0.2772 0.6423
Echinococcus multilocularis allatostatin A receptor 0.0589 0.2772 0.6423
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0193 0.0797 0.1844
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0069 0.0179 0.0177
Brugia malayi G protein-coupled receptor 0.0589 0.2772 0.3014
Mycobacterium ulcerans epoxide hydrolase EphA 0.0197 0.0818 0.0816
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0046 0.0062 0.0553
Mycobacterium ulcerans D-amino acid oxidase Aao 0.017 0.0681 0.0679
Plasmodium vivax aspartyl proteinase, putative 0.0046 0.0062 0.0251
Trichomonas vaginalis tubulin epsilon chain, putative 0.025 0.108 0.8787
Schistosoma mansoni TRABID protein (C64 family) 0.0034 0.0003 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0746 0.5983
Echinococcus multilocularis rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Trichomonas vaginalis tubulin beta chain, putative 0.025 0.108 0.8787
Mycobacterium tuberculosis Possible thiamine biosynthesis oxidoreductase ThiO 0.017 0.0681 0.0742
Brugia malayi brahma associated protein 60 kDa 0.0096 0.031 0.0335
Brugia malayi Dopamine receptor 0.0589 0.2772 0.3014
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0589 0.2772 0.2771
Schistosoma mansoni hypothetical protein 0.0506 0.2357 0.2356
Echinococcus granulosus dro:myosuppressin receptor 0.0589 0.2772 0.6423
Echinococcus granulosus neuropeptide FF receptor 2 0.0589 0.2772 0.6423
Brugia malayi Melatonin receptor type 1A 0.0589 0.2772 0.3014
Leishmania major beta tubulin 0.025 0.108 1
Brugia malayi neuropeptide F receptor 0.0589 0.2772 0.3014
Brugia malayi GnHR receptor homolog 0.1484 0.7233 0.7868
Brugia malayi MH2 domain containing protein 0.0129 0.0478 0.0518
Trypanosoma brucei heat shock protein, putative 0.0141 0.0538 0.4023
Entamoeba histolytica tubulin family protein 0.025 0.108 1
Loa Loa (eye worm) endoplasmin 0.0141 0.0538 0.0536
Echinococcus multilocularis glycerol 3 phosphate dehydrogenase 0.017 0.0681 0.1575
Echinococcus granulosus thioredoxin glutathione reductase 0.0063 0.0148 0.0338
Echinococcus granulosus tubulin subunit beta 0.025 0.108 0.2499
Brugia malayi RE15519p 0.0589 0.2772 0.3014
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.0189 0.0434
Toxoplasma gondii hypothetical protein 0.0116 0.041 0.3783
Trichomonas vaginalis tubulin, putative 0.025 0.108 0.8787
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Trypanosoma brucei beta tubulin 0.025 0.108 0.808
Echinococcus multilocularis dro:myosuppressin receptor 0.0589 0.2772 0.6423
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0589 0.2772 0.6423
Onchocerca volvulus Neuropeptide F receptor homolog 0.0589 0.2772 1
Brugia malayi latrophilin 2 splice variant baaae 0.1059 0.511 0.5558
Schistosoma mansoni neuropeptide F-like receptor 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0135 0.0508 0.1824
Plasmodium falciparum plasmepsin V 0.0046 0.0062 0.0542
Brugia malayi putative neuropeptide receptor NPR1 0.0589 0.2772 0.3014
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Echinococcus multilocularis thioredoxin glutathione reductase 0.0063 0.0148 0.0338
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase, putative 0.017 0.0681 0.6302
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Plasmodium falciparum plasmepsin X 0.0046 0.0062 0.0542
Entamoeba histolytica anaerobic glycerol-3-phosphate dehydrogenase subunit A, putative 0.017 0.0681 0.6214
Plasmodium falciparum plasmepsin IX 0.0046 0.0062 0.0542
Schistosoma mansoni opsin-like receptor 0.0589 0.2772 0.2771
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0589 0.2772 0.6423
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0589 0.2772 0.2771
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.017 0.0681 0.6302
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0057 0.0119 0.0271
Echinococcus multilocularis SWI:SNF matrix associated 0.0096 0.031 0.0714
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0589 0.2772 0.6423
Schistosoma mansoni fad oxidoreductase 0.017 0.0681 0.0679
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0156 0.0611 0.1413
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0003 0.0012
Echinococcus multilocularis GPCR, family 2 0.0506 0.2357 0.5462
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0096 0.031 0.285
Trypanosoma cruzi heat shock protein 85, putative 0.0141 0.0538 0.4969
Plasmodium vivax aspartyl protease, putative 0.0046 0.0062 0.0251
Brugia malayi polk-prov protein 0.0062 0.0145 0.0156
Loa Loa (eye worm) melatonin receptor type 1A 0.0589 0.2772 0.2771
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.007 0.018 0.0179
Schistosoma mansoni hypothetical protein 0.0057 0.0119 0.0117
Echinococcus multilocularis neuropeptides capa receptor 0.0589 0.2772 0.6423
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0245 0.1836
Echinococcus granulosus CD36 class B scavenger receptor 0.0041 0.004 0.0088
Echinococcus granulosus g protein coupled receptor 0.0589 0.2772 0.6423
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0057 0.0119 0.0117
Trichomonas vaginalis glucosylceramidase, putative 0.0279 0.1224 1
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Mycobacterium ulcerans glycerol-3-phosphate dehydrogenase 0.017 0.0681 0.0679
Trypanosoma brucei DNA polymerase IV, putative 0.0083 0.0245 0.1836
Echinococcus granulosus Tubulin beta 2C chain 0.025 0.108 0.2499
Onchocerca volvulus 0.0135 0.0508 0.1824
Echinococcus granulosus orexin receptor type 2 0.0589 0.2772 0.6423
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Loa Loa (eye worm) heat shock protein 90 0.0141 0.0538 0.0536
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0128 0.0471 0.4353
Giardia lamblia Heat shock protein HSP 90-alpha 0.0128 0.0471 0.4218
Echinococcus multilocularis integrin alpha ps 0.0037 0.0018 0.0036
Schistosoma mansoni tubulin subunit beta 0.025 0.108 0.1078
Schistosoma mansoni hypothetical protein 0.0506 0.2357 0.2356
Echinococcus granulosus CD36 class B scavenger receptor 0.0041 0.004 0.0088
Echinococcus granulosus ring and YY1 binding protein 0.0034 0.0003 0.0003
Schistosoma mansoni endoplasmin 0.0141 0.0538 0.0536
Loa Loa (eye worm) hypothetical protein 0.0046 0.0062 0.006
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.004 0.0035 0.0077
Trypanosoma brucei trypanothione reductase 0.0063 0.0148 0.1107
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Onchocerca volvulus Glucosylceramidase homolog 0.0183 0.0746 0.2683
Echinococcus multilocularis rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Plasmodium vivax aspartyl proteinase, putative 0.0193 0.0797 0.7294
Onchocerca volvulus 0.0046 0.0062 0.0211
Echinococcus multilocularis 0.0069 0.0179 0.041
Trypanosoma brucei heat shock protein, putative 0.0141 0.0538 0.4023
Schistosoma mansoni NAD dehydrogenase 0.017 0.0681 0.0679
Brugia malayi Pepsin A precursor 0.0046 0.0062 0.0065
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0589 0.2772 0.3014
Echinococcus granulosus Tubulin beta 2C chain 0.025 0.108 0.2499
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0589 0.2772 0.3014
Brugia malayi hypothetical protein 0.0589 0.2772 0.3014
Loa Loa (eye worm) hypothetical protein 0.0034 0.0003 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0003 0.0024
Onchocerca volvulus 0.0589 0.2772 1
Loa Loa (eye worm) hypothetical protein 0.0369 0.1674 0.1673
Brugia malayi PDZ domain containing protein 0.0051 0.0087 0.0093
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Schistosoma mansoni scavenger receptor class B type-2 (sr-B2) 0.0041 0.004 0.0038
Onchocerca volvulus 0.0589 0.2772 1
Trypanosoma cruzi Heat shock protein 83, putative 0.0141 0.0538 0.4969
Brugia malayi hypothetical protein 0.0589 0.2772 0.3014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0589 0.2772 0.2771
Leishmania major beta tubulin 0.025 0.108 1
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Echinococcus granulosus zinc finger protein Ran binding 0.0034 0.0003 0.0003
Schistosoma mansoni integrin alpha 0.0172 0.0689 0.0687
Giardia lamblia Heat shock protein HSP 90-alpha 0.0141 0.0538 0.4849
Echinococcus granulosus rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Schistosoma mansoni hypothetical protein 0.0506 0.2357 0.2356
Leishmania major beta tubulin 0.025 0.108 1
Echinococcus multilocularis heat shock protein 90 0.0141 0.0538 0.1242
Echinococcus granulosus GPCR family 2 0.0506 0.2357 0.5462
Loa Loa (eye worm) hypothetical protein 0.013 0.0481 0.0479
Echinococcus multilocularis CD36 class B scavenger receptor 0.0041 0.004 0.0088
Schistosoma mansoni ATP:guanidino kinase (Smc74) 0.017 0.0681 0.0679
Trypanosoma brucei heat shock protein, putative 0.0141 0.0538 0.4023
Loa Loa (eye worm) integrin alpha pat-2 0.0264 0.1152 0.115
Trypanosoma cruzi DNA polymerase kappa, putative 0.0083 0.0245 0.2258
Schistosoma mansoni myosin xvIII 0.0589 0.2772 0.2771
Echinococcus multilocularis CD36 class B scavenger receptor 0.0041 0.004 0.0088
Echinococcus multilocularis rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Echinococcus granulosus endoplasmin 0.0128 0.0471 0.1088
Trypanosoma brucei heat shock protein, putative 0.0141 0.0538 0.4023
Brugia malayi putative neuropeptide receptor 0.0589 0.2772 0.3014
Plasmodium falciparum endoplasmin, putative 0.004 0.0034 0.0285
Onchocerca volvulus Lysosome membrane protein 2 homolog 0.0041 0.004 0.0133
Trichomonas vaginalis DNA polymerase eta, putative 0.0083 0.0245 0.1776
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.004 0.0035 0.0036
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0085
Leishmania major hypothetical protein, conserved 0.017 0.0681 0.6302
Schistosoma mansoni fusion 0.0034 0.0003 0.0001
Brugia malayi G-protein coupled receptor 0.0589 0.2772 0.3014
Loa Loa (eye worm) hypothetical protein 0.0041 0.004 0.0038
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0034 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0096 0.031 0.0308
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0045 0.0396
Echinococcus granulosus Tubulin beta 2C chain 0.025 0.108 0.2499
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0046 0.0062 0.006
Schistosoma mansoni heat shock protein 0.0141 0.0538 0.0536
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0145 0.1088
Trypanosoma brucei DNA polymerase IV, putative 0.0069 0.0179 0.1341
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0045 0.0099
Giardia lamblia Grp94/Hsp90 0.0128 0.0471 0.4218
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0746 0.5983
Toxoplasma gondii beta-tubulin, putative 0.025 0.108 1
Trypanosoma cruzi heat shock protein 90, putative 0.0141 0.0538 0.4969
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.0189 0.0434
Echinococcus granulosus adenylate cyclase 9 0.0135 0.0508 0.1174
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Loa Loa (eye worm) hypothetical protein 0.0034 0.0003 0.0001
Brugia malayi hypothetical protein 0.0046 0.0062 0.0065
Echinococcus multilocularis heat shock protein 90 0.0128 0.0471 0.1088
Plasmodium vivax FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.017 0.0681 0.6184
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0035 0.0265
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0589 0.2772 0.6423
Schistosoma mansoni hypothetical protein 0.0034 0.0003 0.0001
Mycobacterium ulcerans thiamine biosynthesis oxidoreductase ThiO 0.017 0.0681 0.0679
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0506 0.2357 0.5462
Echinococcus multilocularis orexin receptor type 2 0.0589 0.2772 0.6423
Schistosoma mansoni hypothetical protein 0.1059 0.511 0.5109
Brugia malayi CD36 family protein 0.0041 0.004 0.0041
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.017 0.0681 0.6302
Trypanosoma cruzi DNA polymerase kappa, putative 0.0083 0.0245 0.2258
Onchocerca volvulus 0.0589 0.2772 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Echinococcus multilocularis rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Toxoplasma gondii aspartyl protease ASP1 0.0193 0.0797 0.7378
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0279 0.1224 0.1222
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.0531 0.1226
Schistosoma mansoni integrin alpha-ps 0.004 0.0033 0.0031
Echinococcus granulosus Zinc finger RanBP2 type 0.0034 0.0003 0.0003
Echinococcus multilocularis neuropeptide receptor A26 0.0589 0.2772 0.6423
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.004 0.0087
Brugia malayi heat shock protein 90 0.0141 0.0538 0.0583
Echinococcus granulosus rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Loa Loa (eye worm) adenylyl cyclase 3 0.0214 0.0902 0.09
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0034 0.0003 0.0003
Mycobacterium ulcerans D-amino acid oxidase Aao 0.204 1 1
Brugia malayi Latrophilin receptor protein 2 0.0506 0.2357 0.2563
Echinococcus multilocularis fmrfamide receptor 0.0589 0.2772 0.6423
Brugia malayi hypothetical protein 0.0589 0.2772 0.3014
Chlamydia trachomatis D-amino acid dehydrogenase 0.017 0.0681 1
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0156 0.0611 0.555
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0045 0.009
Echinococcus granulosus peptide allatostatin:somatostatin 0.0589 0.2772 0.6423
Echinococcus granulosus g protein coupled receptor 0.0589 0.2772 0.6423
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Loa Loa (eye worm) hypothetical protein 0.017 0.0681 0.0679
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0819 0.3916 0.9075
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0034 0.0003 0.0001
Echinococcus granulosus biogenic amine 5HT receptor 0.0589 0.2772 0.6423
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0589 0.2772 0.2771
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0156 0.0611 0.4851
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.017 0.0681 0.5098
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0746 0.5983
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0045 0.0399
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1565 0.7634 0.7634
Schistosoma mansoni opsin-like receptor 0.0589 0.2772 0.2771
Echinococcus granulosus heat shock protein 90 0.0128 0.0471 0.1088
Echinococcus granulosus g-protein coupled receptor 0.0589 0.2772 0.6423
Schistosoma mansoni tubulin subunit beta 0.025 0.108 0.1078
Echinococcus granulosus heat shock protein 90 0.0141 0.0538 0.1242
Schistosoma mansoni biogenic amine receptor 0.0589 0.2772 0.2771
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0245 0.1836
Plasmodium falciparum heat shock protein 90 0.0141 0.0538 0.4964
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0589 0.2772 0.2771
Echinococcus granulosus serotonin receptor 0.0589 0.2772 0.6423
Trypanosoma brucei heat shock protein, putative 0.0141 0.0538 0.4023
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Onchocerca volvulus 0.0589 0.2772 1
Echinococcus multilocularis adenylate cyclase type IX 0.0085 0.0256 0.059
Leishmania major hypothetical protein, conserved 0.0034 0.0003 0.0012
Loa Loa (eye worm) G-protein coupled receptor 0.0589 0.2772 0.2771
Trypanosoma brucei unspecified product 0.0069 0.0179 0.1341
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0034 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.1878 0.9192 0.9192
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0589 0.2772 0.2771
Leishmania major DNA polymerase kappa, putative 0.0042 0.0045 0.0399
Leishmania major beta tubulin 0.025 0.108 1
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0189 0.1416
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0046 0.0062 0.006
Schistosoma mansoni cathepsin D (A01 family) 0.057 0.2674 0.2673
Brugia malayi dimethylglycine dehydrogenase, mitochondrial precursor, putative 0.017 0.0681 0.0739
Giardia lamblia DINP protein human, muc B family 0.0042 0.0045 0.017
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0128 0.0471 0.0469
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0589 0.2772 0.2771
Mycobacterium leprae PROBABLE D-AMINO ACID OXIDASE AAO 0.204 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0035 0.031
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0589 0.2772 0.6423
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.017 0.0681 0.6302
Brugia malayi glutathione reductase 0.0063 0.0148 0.0159
Plasmodium falciparum thioredoxin reductase 0.0063 0.0148 0.1344
Echinococcus granulosus FAD dependent oxidoreductase domain containing protein 0.017 0.0681 0.1575
Loa Loa (eye worm) hypothetical protein 0.0057 0.0119 0.0117
Echinococcus granulosus rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0034 0.0003 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0589 0.2772 0.6423
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Schistosoma mansoni hypothetical protein 0.0589 0.2772 0.2771
Trypanosoma cruzi DNA polymerase kappa, putative 0.0083 0.0245 0.2258
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Echinococcus multilocularis CD36 class B scavenger receptor 0.0041 0.004 0.0088
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0156 0.0611 0.5648
Brugia malayi aspartic protease BmAsp-1, identical 0.0046 0.0062 0.0065
Echinococcus multilocularis heat shock protein 0.0141 0.0538 0.1242
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Echinococcus multilocularis CD36 class B scavenger receptor 0.0041 0.004 0.0088
Loa Loa (eye worm) latrophilin receptor protein 2 0.0506 0.2357 0.2356
Loa Loa (eye worm) hypothetical protein 0.0156 0.0611 0.0609
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.004 0.0035 0.0012
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), mitochondrial 0.017 0.0681 0.5098
Toxoplasma gondii hypothetical protein 0.004 0.0035 0.031
Plasmodium vivax thioredoxin reductase, putative 0.0063 0.0148 0.1077
Echinococcus granulosus CD36 class B scavenger receptor 0.0041 0.004 0.0088
Echinococcus multilocularis rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0245 0.1836
Schistosoma mansoni neuropeptide receptor 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Leishmania major beta tubulin 0.025 0.108 1
Onchocerca volvulus 0.0589 0.2772 1
Echinococcus multilocularis Tubulin beta 2C chain 0.025 0.108 0.2499
Toxoplasma gondii aspartyl protease 0.0046 0.0062 0.0553
Trichomonas vaginalis heat shock protein, putative 0.0128 0.0471 0.3673
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0096 0.031 0.263
Leishmania major beta tubulin 0.025 0.108 1
Echinococcus granulosus g protein coupled receptor 0.0589 0.2772 0.6423
Schistosoma mansoni growth hormone secretagogue receptor 0.0589 0.2772 0.2771
Brugia malayi Serotonin receptor 0.0589 0.2772 0.3014
Echinococcus multilocularis lysosome membrane protein 2 0.0041 0.004 0.0088
Onchocerca volvulus Dimethylglycine dehydrogenase, mitochondrial homolog 0.017 0.0681 0.2449
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0245 0.1836
Schistosoma mansoni biogenic amine receptor 0.0589 0.2772 0.2771
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0034 0.0003 0.0024
Toxoplasma gondii heat shock protein 90, putative 0.0141 0.0538 0.4969
Schistosoma mansoni hypothetical protein 0.0096 0.031 0.0308
Leishmania major beta tubulin 0.025 0.108 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0589 0.2772 0.2771
Onchocerca volvulus 0.0096 0.031 0.1108
Echinococcus multilocularis Tubulin beta 2C chain 0.025 0.108 0.2499
Leishmania major beta tubulin 0.025 0.108 1
Mycobacterium ulcerans DNA polymerase IV 0.0083 0.0245 0.0243
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0176 0.071 0.6488
Loa Loa (eye worm) hypothetical protein 0.0041 0.004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0034 0.0003 0.0001
Schistosoma mansoni tubulin subunit beta 0.025 0.108 0.1078
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0145 0.1088
Trypanosoma cruzi heat shock protein 90, putative 0.0114 0.0404 0.3729
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0045 0.0089
Trypanosoma cruzi heat shock protein 85, putative 0.0141 0.0538 0.4969
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Trypanosoma cruzi beta tubulin, putative 0.025 0.108 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0589 0.2772 0.6423
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0156 0.0611 0.5515
Echinococcus granulosus beta tubulin 0.025 0.108 0.2499
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.005 0.0081 0.0184
Loa Loa (eye worm) glutathione reductase 0.0063 0.0148 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0045 0.0337
Echinococcus multilocularis endoplasmin 0.0128 0.0471 0.1088
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0034 0.0003 0.0024
Schistosoma mansoni amine GPCR 0.0589 0.2772 0.2771
Echinococcus granulosus SWI:SNF matrix associated 0.0096 0.031 0.0714
Brugia malayi Thioredoxin reductase 0.0063 0.0148 0.0159
Schistosoma mansoni neuropeptide receptor 0.0589 0.2772 0.2771
Schistosoma mansoni zinc finger protein 0.0034 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.0096 0.031 0.0308
Plasmodium vivax glutathione reductase, putative 0.0063 0.0148 0.1077
Loa Loa (eye worm) hypothetical protein 0.0193 0.0797 0.0795
Echinococcus granulosus tachykinin peptides receptor 99D 0.0899 0.4315 1
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0156 0.0611 0.0609
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0034 0.0003 0.0012
Trichomonas vaginalis tubulin alpha chain, putative 0.025 0.108 0.8787
Echinococcus granulosus hypothetical protein 0.0589 0.2772 0.6423
Echinococcus multilocularis ring and YY1 binding protein 0.0034 0.0003 0.0003
Leishmania major beta tubulin 0.025 0.108 1
Treponema pallidum heat shock protein 90 0.0128 0.0471 0.5
Giardia lamblia Rab geranylgeranyltransferase 0.0156 0.0611 0.555
Echinococcus multilocularis serotonin receptor 0.0589 0.2772 0.6423
Giardia lamblia Rab geranylgeranyltransferase 0.004 0.0035 0.0079
Leishmania major beta tubulin 0.025 0.108 1
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.017 0.0681 0.6302
Onchocerca volvulus 0.0589 0.2772 1
Echinococcus granulosus neuropeptide receptor A26 0.0589 0.2772 0.6423
Schistosoma mansoni cd36 antigen 0.0041 0.004 0.0038
Loa Loa (eye worm) transcription factor SMAD2 0.0129 0.0478 0.0476
Schistosoma mansoni memapsin-2 (A01 family) 0.0046 0.0062 0.006
Loa Loa (eye worm) acetyltransferase 0.0144 0.0551 0.0549
Schistosoma mansoni cathepsin D (A01 family) 0.057 0.2674 0.2673
Brugia malayi Integrin alpha pat-2 precursor 0.0172 0.0689 0.0747
Onchocerca volvulus 0.0589 0.2772 1
Plasmodium vivax plasmepsin V, putative 0.0046 0.0062 0.0251
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0746 0.5983
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0128 0.0471 0.5
Giardia lamblia Beta tubulin 0.025 0.108 1
Plasmodium vivax endoplasmin, putative 0.0141 0.0538 0.4808
Trichomonas vaginalis glucosylceramidase, putative 0.0193 0.0795 0.6396
Echinococcus multilocularis serotonin receptor 0.0589 0.2772 0.6423
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0589 0.2772 0.3014
Brugia malayi Dopamine receptor protein 1 0.0589 0.2772 0.3014
Plasmodium vivax aspartyl protease, putative 0.0046 0.0062 0.0251
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0003 0.0012
Echinococcus granulosus 7TM GPCR rhodopsin 0.0589 0.2772 0.6423
Onchocerca volvulus 0.0589 0.2772 1
Schistosoma mansoni hypothetical protein 0.0057 0.0119 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0245 0.1836
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0589 0.2772 0.2771
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0046 0.0062 0.006
Loa Loa (eye worm) TYRA-2 protein 0.0589 0.2772 0.2771
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0176 0.071 0.6488
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.004 0.0035 0.0077
Echinococcus multilocularis G-protein coupled receptor, putative 0.0589 0.2772 0.6423
Echinococcus multilocularis tubulin subunit beta 0.025 0.108 0.2499
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0589 0.2772 0.2771
Onchocerca volvulus 0.0589 0.2772 1
Schistosoma mansoni hypothetical protein 0.0506 0.2357 0.2356
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.005 0.0081 0.0079
Leishmania major beta tubulin 0.025 0.108 1
Onchocerca volvulus 0.0589 0.2772 1
Brugia malayi Protein kinase domain containing protein 0.0841 0.4026 0.4378
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0589 0.2772 0.2771
Schistosoma mansoni serine-type protease inhibitor 0.0441 0.203 0.2029
Brugia malayi cDNA sequence BC016226 0.017 0.0681 0.0739
Brugia malayi YY1-associated factor 2 0.0034 0.0003 0.0001
Loa Loa (eye worm) neuropeptide F receptor 0.0589 0.2772 0.2771
Echinococcus granulosus CD36 class B scavenger receptor 0.0041 0.004 0.0088
Loa Loa (eye worm) tubulin beta-2A chain 0.025 0.108 0.1078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0589 0.2772 0.2771
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0506 0.2357 0.5462
Leishmania major beta tubulin 0.025 0.108 1
Echinococcus multilocularis G protein coupled receptor 139 0.0694 0.3294 0.7633
Echinococcus granulosus tubulin beta 1 chain 0.025 0.108 0.2499
Echinococcus multilocularis neuropeptide s receptor 0.0589 0.2772 0.6423
Echinococcus multilocularis SWI:SNF matrix associated 0.0096 0.031 0.0714
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0046 0.0062 0.006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0589 0.2772 0.2771
Trypanosoma brucei FAD dependent oxidoreductase, putative 0.017 0.0681 0.5098
Schistosoma mansoni endoplasmin 0.0141 0.0538 0.0536
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0035 0.031
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0819 0.3916 0.9075
Plasmodium falciparum plasmepsin I 0.0193 0.0797 0.7375
Toxoplasma gondii heat shock protein HSP90 0.0141 0.0538 0.4969
Echinococcus multilocularis tubulin beta 1 chain 0.025 0.108 0.2499
Echinococcus multilocularis Tubulin beta 2C chain 0.025 0.108 0.2499
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0589 0.2772 0.6423
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.0551 0.0597
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0746 0.5983
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0589 0.2772 0.3014
Trypanosoma brucei beta tubulin 0.025 0.108 0.808
Loa Loa (eye worm) apoptosis regulator protein 0.0057 0.0119 0.0117
Loa Loa (eye worm) hypothetical protein 0.0062 0.0145 0.0143
Schistosoma mansoni tubulin subunit beta 0.025 0.108 0.1078
Echinococcus granulosus neuropeptide receptor 0.0589 0.2772 0.6423
Schistosoma mansoni hypothetical protein 0.0589 0.2772 0.2771
Trichomonas vaginalis glucosylceramidase, putative 0.0279 0.1224 1
Brugia malayi pyruvate dehydrogenase phosphatase regulatory subunit precursor 0.017 0.0681 0.0739
Schistosoma mansoni opsin-like receptor 0.0589 0.2772 0.2771
Echinococcus multilocularis neuropeptide FF receptor 2 0.0589 0.2772 0.6423
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0245 0.1836
Echinococcus granulosus fmrfamide receptor 0.0589 0.2772 0.6423
Plasmodium falciparum plasmepsin III 0.0046 0.0062 0.0542
Echinococcus multilocularis rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Brugia malayi Tubulin beta-1 chain 0.025 0.108 0.1173
Schistosoma mansoni amine GPCR 0.0589 0.2772 0.2771
Trypanosoma brucei heat shock protein 90, putative 0.0141 0.0538 0.4023
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0128 0.0471 0.0513
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.004 0.0035 0.031
Echinococcus multilocularis fmrfamide receptor 0.0589 0.2772 0.6423
Trypanosoma cruzi heat shock protein 90, putative 0.0128 0.0471 0.4353
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0589 0.2772 0.6423
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0057 0.0119 0.0271
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Toxoplasma gondii beta-1 tubulin, putative 0.025 0.108 1
Echinococcus granulosus heat shock protein 0.0141 0.0538 0.1242
Loa Loa (eye worm) hypothetical protein 0.0506 0.2357 0.2356
Echinococcus granulosus glycerol 3 phosphate dehydrogenase 0.017 0.0681 0.1575
Toxoplasma gondii FAD-dependent glycerol-3-phosphate dehydrogenase 0.017 0.0681 0.6302
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0045 0.009
Schistosoma mansoni alpha-1 adrenergic receptor 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Trypanosoma brucei heat shock protein 90, putative 0.0141 0.0538 0.4023
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0156 0.0611 0.0663
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0046 0.0062 0.006
Echinococcus multilocularis neuropeptides capa receptor 0.0589 0.2772 0.6423
Echinococcus multilocularis g protein coupled receptor 0.0589 0.2772 0.6423
Mycobacterium leprae Probable cholesterol oxidase precursor ChoD (cholesterol-O2 oxidoreductase) 0.017 0.0681 0.0679
Echinococcus multilocularis SWI:SNF matrix associated 0.0096 0.031 0.0714
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.004 0.0035 0.0079
Mycobacterium ulcerans glycerol-3-phosphate dehydrogenase GlpD2 0.017 0.0681 0.0679
Echinococcus multilocularis somatostatin receptor 0.0589 0.2772 0.6423
Leishmania major heat shock protein 83-1 0.0141 0.0538 0.4969
Loa Loa (eye worm) neuropeptide F receptor 0.0589 0.2772 0.2771
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0589 0.2772 0.6423
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0589 0.2772 0.2771
Echinococcus granulosus Tubulin beta 2C chain 0.025 0.108 0.2499
Schistosoma mansoni apoptosis regulator bax 0.0057 0.0119 0.0117
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0083 0.0245 0.1776
Echinococcus multilocularis g protein coupled receptor 0.0589 0.2772 0.6423
Plasmodium vivax aspartyl protease, putative 0.0046 0.0062 0.0251
Brugia malayi SWIB/MDM2 domain containing protein 0.0096 0.031 0.0335
Mycobacterium ulcerans heat shock protein 90 0.0128 0.0471 0.0469
Brugia malayi ORL1-like opioid receptor 0.0589 0.2772 0.3014
Schistosoma mansoni histamine h1 receptor 0.0589 0.2772 0.2771
Onchocerca volvulus 0.0589 0.2772 1
Leishmania major beta tubulin 0.025 0.108 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.025 0.108 0.8787
Trichomonas vaginalis glucosylceramidase, putative 0.0279 0.1224 1
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0034 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0589 0.2772 0.2771
Brugia malayi hypothetical protein 0.0589 0.2772 0.3014
Onchocerca volvulus 0.0046 0.0062 0.0211
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0096 0.031 0.2859
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Trichomonas vaginalis glucosylceramidase, putative 0.0193 0.0795 0.6396
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0193 0.0797 0.0795
Plasmodium vivax plasmepsin IV, putative 0.0193 0.0797 0.7294
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0589 0.2772 0.2771
Onchocerca volvulus 0.0589 0.2772 1
Echinococcus granulosus 3'partial|membrane associated guanylate kinase ww and pdz 0.005 0.0081 0.0184
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0589 0.2772 0.6423
Echinococcus multilocularis tubulin, beta 4A class IVa 0.025 0.108 0.2499
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0096 0.031 0.2859
Brugia malayi sulfakinin receptor protein 0.0589 0.2772 0.3014
Trypanosoma brucei L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.017 0.0681 0.5098
Brugia malayi brahma associated protein 60 kDa 0.0096 0.031 0.0335
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Loa Loa (eye worm) hypothetical protein 0.0041 0.004 0.0038
Echinococcus granulosus neuropeptide s receptor 0.0589 0.2772 0.6423
Loa Loa (eye worm) hypothetical protein 0.0589 0.2772 0.2771
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0746 0.5983
Echinococcus multilocularis CD36 class B scavenger receptor 0.0041 0.004 0.0088
Echinococcus multilocularis dna polymerase kappa 0.0083 0.0245 0.0564
Trypanosoma cruzi FAD dependent oxidoreductase, putative 0.017 0.0681 0.6302
Echinococcus granulosus biogenic amine 5HT receptor 0.0589 0.2772 0.6423
Echinococcus multilocularis rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Brugia malayi hypothetical protein 0.0589 0.2772 0.3014
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0046 0.0062 0.006
Brugia malayi hypothetical protein 0.0589 0.2772 0.3014
Loa Loa (eye worm) tubulin beta-4 chain 0.025 0.108 0.1078
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0589 0.2772 0.6423
Toxoplasma gondii hypothetical protein 0.017 0.0681 0.6302
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0156 0.0611 0.1413
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0589 0.2772 0.2771
Echinococcus multilocularis rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.0189 0.0204
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0506 0.2357 0.2563
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0069 0.0179 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.031 0.232
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.0189 0.0187
Schistosoma mansoni d-amino acid oxidase 0.204 1 1
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0034 0.0003 0.0001
Brugia malayi Endoplasmin precursor 0.0141 0.0538 0.0583
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0716 0.3401 0.7881
Brugia malayi hypothetical protein 0.0041 0.004 0.0041
Schistosoma mansoni biogenic amine (5HT) receptor 0.0589 0.2772 0.2771
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0156 0.0611 0.4851
Trypanosoma brucei electron transfer flavoprotein-ubiquinone oxidoreductase, putative 0.017 0.0681 0.5098
Loa Loa (eye worm) hypothetical protein 0.0841 0.4026 0.4025
Echinococcus granulosus rhodopsin orphan GPCR 0.0589 0.2772 0.6423
Loa Loa (eye worm) hypothetical protein 0.0041 0.004 0.0038
Onchocerca volvulus 0.0589 0.2772 1
Loa Loa (eye worm) hypothetical protein 0.017 0.0681 0.0679
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.0189 0.154
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0193 0.0797 0.6412
Echinococcus granulosus tubulin beta 4A class IVa 0.025 0.108 0.2499
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0128 0.0471 0.1088
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0156 0.0611 0.4851

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 50 nM Inhibition of recombinant human sEH expressed in Sf9 cells using CMNPC as substrate assessed as release of 6-methoxy-2-naphthaldehyde preincubated for 10 mins before substrate addition measured after 10 mins by fluorometer analysis ChEMBL. 24433964

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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