Detailed information for compound 189224

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 243.283 | Formula: C9H13N3O3S
  • H donors: 2 H acceptors: 2 LogP: -1.23 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCC1OC(CC1S)n1ccc(nc1=O)N
  • InChi: 1S/C9H13N3O3S/c10-7-1-2-12(9(14)11-7)8-3-6(16)5(4-13)15-8/h1-2,5-6,8,13,16H,3-4H2,(H2,10,11,14)
  • InChiKey: FYFSTKQXVINVRW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0114 0.0091 0.8656
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0054 0.0023 0.0009
Loa Loa (eye worm) hypothetical protein 0.0057 0.0026 0.002
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0052 0.002 0.0005
Brugia malayi Nuclear hormone receptor E75 0.0057 0.0026 0.002
Loa Loa (eye worm) protein kinase domain-containing protein 0.0052 0.002 0.0015
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.002 0.0005
Loa Loa (eye worm) hypothetical protein 0.017 0.0155 0.015
Giardia lamblia Protein 21.1 0.0052 0.002 0.0034
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0082 0.0054 0.5314
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.012 0.0098 0.0093
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0052 0.002 0.0005
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0052 0.002 0.0015
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.012 0.0098 0.0093
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0052 0.002 0.8067
Echinococcus granulosus nuclear receptor nhr 48 0.0057 0.0026 0.0013
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0087 0.006 0.481
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0274 0.0274 0.035
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0632 0.0682 0.3697
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0021 1
Echinococcus multilocularis glutamate receptor 2 0.0054 0.0023 0.0009
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Onchocerca volvulus 0.017 0.0155 0.0849
Trypanosoma brucei Flagellum attachment zone protein 20 0.0052 0.002 0.0426
Mycobacterium leprae Polyketide synthase Pks13 0.0124 0.0102 1
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0052 0.002 0.0015
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.006 0.003 0.0024
Entamoeba histolytica serine/threonine kinase, putative 0.0052 0.002 0.8067
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Loa Loa (eye worm) hypothetical protein 0.0057 0.0026 0.002
Echinococcus granulosus integrin beta 2 0.6479 0.7363 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.002 0.8067
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0071 0.0042 0.2482
Echinococcus multilocularis neuropeptides capa receptor 0.0207 0.0197 0.0246
Trypanosoma cruzi protein kinase, putative 0.0052 0.002 0.0426
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0052 0.002 0.0021
Echinococcus granulosus raf serine:threonine protein kinase 0.0052 0.002 0.0005
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0632 0.0682 0.3697
Loa Loa (eye worm) hypothetical protein 0.027 0.0269 0.0264
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.1625 0.1818 0.2452
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0041 0.0008 0.0002
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0114 0.0091 0.8656
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0082 0.0054 0.5314
Loa Loa (eye worm) ube2i2 protein 0.0049 0.0016 0.0011
Onchocerca volvulus 0.0057 0.0026 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.002 0.0015
Plasmodium falciparum protein kinase, putative 0.0052 0.002 0.0495
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.002 0.8067
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0052 0.002 0.0034
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.002 0.0005
Echinococcus multilocularis epidermal growth factor receptor 0.0052 0.002 0.0005
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0117 0.0094 0.0089
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.012 0.0098 0.0112
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0114 0.0091 0.0102
Schistosoma mansoni protein kinase 0.0133 0.0113 0.0194
Brugia malayi nuclear receptor NHR-88 0.0057 0.0026 0.002
Plasmodium vivax tyrosine kinase-like protein, putative 0.0052 0.002 0.0495
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0087 0.006 0.481
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0052 0.002 0.0034
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Entamoeba histolytica hypothetical protein 0.0052 0.002 0.8067
Loa Loa (eye worm) TK/ABL protein kinase 0.0052 0.002 0.0015
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Entamoeba histolytica ankyrin repeat protein 0.0052 0.002 0.8067
Mycobacterium ulcerans Type I modular polyketide synthase 0.0082 0.0054 0.4065
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Echinococcus granulosus nuclear receptor 2DBD gamma 0.012 0.0098 0.0112
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0052 0.002 0.0005
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0052 0.002 0.0005
Echinococcus multilocularis natriuretic peptide receptor 1 0.0052 0.002 0.0005
Toxoplasma gondii subtilisin SUB11 0.0114 0.0091 0.5626
Schistosoma mansoni protein kinase 0.0052 0.002 0.0034
Brugia malayi celfurPC protein 0.2157 0.2425 0.2421
Trypanosoma brucei Pseudokinase, putative 0.0052 0.002 0.0426
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0052 0.002 0.0021
Entamoeba histolytica serine/threonine kinase, putative 0.0052 0.002 0.8067
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.012 0.0098 0.0112
Echinococcus multilocularis kinase suppressor of Ras 1 0.0052 0.002 0.0005
Loa Loa (eye worm) TK protein kinase 0.0052 0.002 0.0015
Loa Loa (eye worm) steroid hormone receptor 0.012 0.0098 0.0093
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Loa Loa (eye worm) TK/EPH protein kinase 0.0052 0.002 0.0015
Brugia malayi Steroid receptor seven-up type 2 0.012 0.0098 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Echinococcus granulosus integrin linked protein kinase 0.0052 0.002 0.0005
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0227 0.022 0.0215
Brugia malayi metalloprotease 0.0076 0.0047 0.0042
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Echinococcus multilocularis protein kinase 0.0052 0.002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0057 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0084 0.0057 0.0052
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0057 0.0026 0.0013
Schistosoma mansoni hypothetical protein 0.006 0.003 0.0051
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0054 0.0023 0.0009
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.002 0.8067
Toxoplasma gondii subtilisin SUB12 0.0114 0.0091 0.5626
Loa Loa (eye worm) nuclear hormone receptor 0.0057 0.0026 0.002
Brugia malayi Nuclear hormone receptor E75 0.0057 0.0026 0.002
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0054 0.0023 0.0009
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0052 0.002 0.0005
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.0015
Plasmodium vivax subtilisin-like serine protease, putative 0.0114 0.0091 1
Loa Loa (eye worm) angiogenesis inhibito 0.0076 0.0047 0.0042
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0082 0.0054 0.5314
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.0015
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0066 0.0037 0.3587
Loa Loa (eye worm) TK/CSK protein kinase 0.0052 0.002 0.0015
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0087 0.006 0.481
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0114 0.0091 0.0157
Echinococcus multilocularis tyrosine protein kinase shark 0.0052 0.002 0.0005
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0114 0.0091 0.8939
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Brugia malayi Protein kinase domain containing protein 0.0074 0.0046 0.004
Loa Loa (eye worm) hypothetical protein 0.0057 0.0026 0.002
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Brugia malayi nuclear receptor RXR 0.0064 0.0034 0.0028
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0052 0.002 0.0005
Echinococcus multilocularis insulin receptor 0.0052 0.002 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.012 0.0098 0.0112
Brugia malayi SH2 domain containing protein 0.0052 0.002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.0015
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Echinococcus granulosus activated cdc42 kinase 1 0.0052 0.002 0.0005
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Loa Loa (eye worm) hypothetical protein 0.017 0.0155 0.015
Toxoplasma gondii protein kinase 0.0052 0.002 0.0713
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Echinococcus granulosus c src tyrosine kinase 0.0052 0.002 0.0005
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Echinococcus multilocularis integrin linked protein kinase 0.0052 0.002 0.0005
Schistosoma mansoni nuclear hormone receptor 0.0057 0.0026 0.0044
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Loa Loa (eye worm) TK/FAK protein kinase 0.0052 0.002 0.0015
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0065 0.0035 0.172
Plasmodium vivax subtilisin-like protease 2, putative 0.0114 0.0091 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0052 0.002 0.0005
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0632 0.0682 0.3697
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0048 0.0016 0.1555
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.002 0.8067
Onchocerca volvulus 0.0114 0.0091 0.0449
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0052 0.002 0.0015
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0082 0.0055 0.5353
Brugia malayi Metabotropic glutamate receptor precursor. 0.0063 0.0032 0.0027
Schistosoma mansoni ephrin receptor 0.0052 0.002 0.0034
Loa Loa (eye worm) TK protein kinase 0.0052 0.002 0.0015
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0085 0.0058 0.565
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0052 0.002 0.0015
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0052 0.002 0.0005
Loa Loa (eye worm) hypothetical protein 0.012 0.0098 0.0093
Loa Loa (eye worm) apoptosis regulator protein 0.006 0.003 0.0024
Echinococcus granulosus tyrosine protein kinase csk 0.0052 0.002 0.0005
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0087 0.006 0.5902
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0057 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.1321 0.147 0.1465
Loa Loa (eye worm) TK protein kinase 0.0052 0.002 0.0015
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0053 0.0021 0.0528
Schistosoma mansoni protein kinase 0.0053 0.0021 0.0036
Brugia malayi SH2 domain containing protein 0.0052 0.002 0.0015
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Echinococcus multilocularis activated cdc42 kinase 1 0.0052 0.002 0.0005
Onchocerca volvulus Fatty acid synthase homolog 0.0153 0.0135 0.0727
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0052 0.002 0.0034
Brugia malayi Receptor family ligand binding region containing protein 0.0073 0.0044 0.0039
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Brugia malayi Guanylyl cyclase protein 23 0.0073 0.0044 0.0039
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0052 0.002 0.0713
Entamoeba histolytica hypothetical protein 0.0052 0.002 0.8067
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0517 0.0552 0.2972
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Onchocerca volvulus 0.0079 0.0051 0.0197
Schistosoma mansoni protein tyrosine kinase 0.0052 0.002 0.0034
Loa Loa (eye worm) hypothetical protein 0.0064 0.0034 0.0028
Echinococcus granulosus ephrin type A receptor 4 A 0.0052 0.002 0.0005
Entamoeba histolytica tyrosin kinase, putative 0.0052 0.002 0.8067
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0085 0.0058 0.4491
Loa Loa (eye worm) metalloprotease 0.0076 0.0047 0.0042
Echinococcus multilocularis tyrosine protein kinase Srms 0.0052 0.002 0.0005
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.002 0.0015
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0757 0.0825 0.1101
Loa Loa (eye worm) TK protein kinase 0.0052 0.002 0.0015
Brugia malayi EGF-like domain containing protein 0.017 0.0155 0.0149
Loa Loa (eye worm) hypothetical protein 0.3203 0.362 0.3617
Echinococcus granulosus glutamate NMDA receptor subunit 0.0279 0.028 0.0359
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0057 0.0026 0.002
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Giardia lamblia High cysteine protein 0.017 0.0155 0.1282
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Brugia malayi Nuclear hormone receptor family member nhr-40 0.012 0.0098 0.0093
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0098 0.0073 0.0125
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1625 0.1818 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.0015
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0082 0.0054 0.0049
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.002 0.8067
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Schistosoma mansoni hypothetical protein 0.0105 0.0081 0.0138
Brugia malayi ecdysone receptor 0.0057 0.0026 0.002
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0052 0.002 0.0005
Onchocerca volvulus 0.0057 0.0026 0.0035
Brugia malayi nuclear receptor RXR 0.0057 0.0026 0.002
Giardia lamblia Tenascin-like 0.017 0.0155 0.1282
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0117 0.0094 0.0089
Loa Loa (eye worm) hypothetical protein 0.016 0.0144 0.0139
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0052 0.002 0.0015
Brugia malayi integrin-linked kinase 0.0052 0.002 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.012 0.0098 0.0093
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.0015
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.002 0.8067
Mycobacterium ulcerans polyketide synthase Pks13 0.0124 0.0102 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.012 0.0098 0.0169
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.0076 0.007
Toxoplasma gondii type I fatty acid synthase, putative 0.006 0.003 0.1379
Echinococcus granulosus tyrosine kinase 0.0052 0.002 0.0005
Echinococcus granulosus disintegrin and metalloproteinase 0.0114 0.0091 0.0101
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.012 0.0098 0.0112
Brugia malayi hypothetical protein 0.0064 0.0034 0.0028
Schistosoma mansoni tyrosine kinase 0.0073 0.0044 0.0076
Schistosoma mansoni metabotropic glutamate receptor 0.0055 0.0024 0.004
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.012 0.0098 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Schistosoma mansoni protein kinase 0.0052 0.002 0.0034
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-49 0.012 0.0098 0.0093
Echinococcus granulosus kinase suppressor of Ras 1 0.0052 0.002 0.0005
Entamoeba histolytica tyrosin kinase, putative 0.0052 0.002 0.8067
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Schistosoma mansoni nuclear receptor 0.0057 0.0026 0.0044
Chlamydia trachomatis glutamine binding protein 0.0085 0.0058 0.5
Loa Loa (eye worm) nuclear receptor nhr-7B 0.1377 0.1535 0.153
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0052 0.002 0.0005
Plasmodium falciparum tyrosine kinase-like protein 0.0052 0.002 0.0495
Schistosoma mansoni protein kinase 0.0053 0.0021 0.0036
Giardia lamblia High cysteine protein 0.017 0.0155 0.1282
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.002 0.0021
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.002 0.8067
Echinococcus multilocularis protein kinase 0.0052 0.002 0.0005
Brugia malayi proprotein convertase 2 0.1681 0.1881 0.1876
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.0015
Brugia malayi hypothetical protein 0.0052 0.002 0.0015
Schistosoma mansoni protein kinase 0.0133 0.0113 0.0194
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Echinococcus multilocularis ephrin type A receptor 4 A 0.0052 0.002 0.0005
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0158 0.0141 0.0136
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0114 0.0091 0.8939
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0085 0.0058 0.5
Entamoeba histolytica hypothetical protein, conserved 0.0052 0.002 0.8067
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0091 0.0416
Schistosoma mansoni protein kinase 0.0133 0.0113 0.0194
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0052 0.002 0.0426
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0057 0.0026 0.0013
Schistosoma mansoni hypothetical protein 0.0069 0.0039 0.0067
Loa Loa (eye worm) hypothetical protein 0.006 0.003 0.0024
Echinococcus multilocularis tyrosine protein kinase Blk 0.0052 0.002 0.0005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.012 0.0098 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.002 0.0021
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Echinococcus multilocularis c src tyrosine kinase 0.0052 0.002 0.0005
Toxoplasma gondii protein kinase domain-containing protein 0.0052 0.002 0.0713
Brugia malayi C-terminal src kinase protein 1 0.0052 0.002 0.0015
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0114 0.0091 0.0086
Plasmodium falciparum protein kinase, putative 0.0053 0.0021 0.0614
Schistosoma mansoni dihydroceramide desaturase 0.0114 0.0091 0.0155
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0052 0.002 0.0034
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0087 0.006 0.481
Echinococcus multilocularis integrin beta 2 0.6479 0.7363 1
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.012 0.0098 0.0093
Schistosoma mansoni protein kinase 0.0052 0.002 0.0034
Loa Loa (eye worm) integrin beta-2 0.8787 1 1
Trypanosoma brucei protein kinase, putative 0.0053 0.0021 0.0528
Echinococcus granulosus neuropeptides capa receptor 0.0207 0.0197 0.0246
Loa Loa (eye worm) hypothetical protein 0.0057 0.0026 0.002
Schistosoma mansoni protein kinase 0.0052 0.002 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Trichomonas vaginalis STE family protein kinase 0.0052 0.002 0.0021
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.002 0.8067
Echinococcus granulosus Nuclear hormone receptor HR96 0.0057 0.0026 0.0013
Loa Loa (eye worm) hypothetical protein 0.1353 0.1507 0.1502
Loa Loa (eye worm) hypothetical protein 0.2675 0.3017 0.3013
Brugia malayi Nuclear hormone receptor family member nhr-19 0.012 0.0098 0.0093
Echinococcus multilocularis tyrosine protein kinase HCK 0.0052 0.002 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.0064 0.0034 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Giardia lamblia Tenascin-37 0.017 0.0155 0.1282
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0052 0.002 0.0005
Loa Loa (eye worm) hypothetical protein 0.017 0.0155 0.015
Trypanosoma cruzi subtilisin peptidase 0.0114 0.0091 0.86
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Echinococcus multilocularis tyrosine protein kinase csk 0.0052 0.002 0.0005
Loa Loa (eye worm) TK/ALK protein kinase 0.0074 0.0046 0.004
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Loa Loa (eye worm) hypothetical protein 0.012 0.0098 0.0093
Echinococcus granulosus nmda type glutamate receptor 0.0118 0.0096 0.0108
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0274 0.0274 0.047
Schistosoma mansoni Tr4/Tr2 (homologue) 0.012 0.0098 0.0169
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0052 0.002 0.0005
Brugia malayi Tyrosine-protein kinase PR2 0.0052 0.002 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0517 0.0552 0.2972
Echinococcus multilocularis epidermal growth factor receptor 0.0052 0.002 0.0005
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0227 0.022 0.0277
Echinococcus multilocularis Furin 1 0.0632 0.0682 0.0907
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Trichomonas vaginalis hypothetical protein 0.0517 0.0552 0.2972
Echinococcus multilocularis integrin alpha ps 0.0219 0.0211 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.002 0.0021
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Schistosoma mansoni retinoic acid receptor RXR 0.087 0.0955 0.164
Schistosoma mansoni steroid hormone receptor ad4bp 0.012 0.0098 0.0169
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0082 0.0054 0.4065
Trichomonas vaginalis conserved hypothetical protein 0.0517 0.0552 0.2972
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0053 0.0021 0.0006
Toxoplasma gondii subtilisin SUB8 0.0114 0.0091 0.5626
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Brugia malayi steroid hormone receptor 0.012 0.0098 0.0093
Mycobacterium leprae Possible secreted protease 0.0114 0.0091 0.8656
Mycobacterium ulcerans polyketide synthase 0.0082 0.0054 0.4065
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Entamoeba histolytica hypothetical protein 0.0052 0.002 0.8067
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0091 0.0416
Echinococcus granulosus tyrosine protein kinase ABL1 0.0052 0.002 0.0005
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0052 0.002 0.0005
Brugia malayi EGF-like domain containing protein 0.017 0.0155 0.0149
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0039 0.0034
Loa Loa (eye worm) TK/ACK protein kinase 0.0052 0.002 0.0015
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0052 0.002 0.0005
Schistosoma mansoni zinc finger protein 0.0057 0.0026 0.0044
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0057 0.0026 0.002
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Mycobacterium leprae Probable polyketide synthase Pks1 0.0087 0.006 0.481
Brugia malayi nuclear hormone receptor 0.1377 0.1535 0.153
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0125 0.0104 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0052 0.002 0.0005
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0064 0.0034 0.0023
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0052 0.002 0.0015
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0052 0.002 0.0005
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0114 0.0091 0.8656
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.3204 0.3621 0.4907
Mycobacterium ulcerans Type I modular polyketide synthase 0.0082 0.0054 0.4065
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Brugia malayi Trypsin family protein 0.0098 0.0073 0.0067
Loa Loa (eye worm) hypothetical protein 0.0384 0.0399 0.0394
Mycobacterium ulcerans thioesterase TesA 0.0071 0.0042 0.2482
Loa Loa (eye worm) TK/RYK protein kinase 0.0052 0.002 0.0015
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0045 0.0012 0.0006
Echinococcus granulosus tyrosine protein kinase 0.0052 0.002 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.002 0.0034
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0054 0.0023 0.0009
Echinococcus granulosus membrane bound transcription factor site 1 0.0114 0.0091 0.0102
Loa Loa (eye worm) RGC/RGC protein kinase 0.0073 0.0044 0.0039
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0114 0.0091 0.8939
Trichomonas vaginalis conserved hypothetical protein 0.0517 0.0552 0.2972
Echinococcus multilocularis tyrosine protein kinase csk 0.0052 0.002 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0632 0.0682 0.1173
Loa Loa (eye worm) RGC/RGC protein kinase 0.0073 0.0044 0.0039
Loa Loa (eye worm) hypothetical protein 0.0057 0.0026 0.002
Echinococcus multilocularis tyrosine protein kinase csk 0.0052 0.002 0.0005
Loa Loa (eye worm) TK/ROR protein kinase 0.0069 0.004 0.0035
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Plasmodium falciparum subtilisin-like protease 3 0.0114 0.0091 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.012 0.0098 0.0112
Echinococcus granulosus tyrosine protein kinase Src42A 0.0052 0.002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.0015
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0052 0.002 0.0021
Toxoplasma gondii subtilisin SUB6 0.0114 0.0091 0.5626
Mycobacterium ulcerans polyketide synthase 0.0087 0.006 0.481
Plasmodium falciparum protein kinase, putative 0.0052 0.002 0.0495
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0052 0.002 0.0005
Echinococcus granulosus tyrosine protein kinase csk 0.0052 0.002 0.0005
Giardia lamblia Kinase 0.0052 0.002 0.0034
Plasmodium vivax protein kinase, putative 0.0052 0.002 0.0495
Brugia malayi hypothetical protein 0.0064 0.0034 0.0028
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.3204 0.3621 0.4907
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0052 0.002 0.0015
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0118 0.0096 0.0108
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.012 0.0098 0.0093
Schistosoma mansoni thyroid hormone receptor 0.012 0.0098 0.0169
Echinococcus granulosus FTZ F1 alpha 0.012 0.0098 0.0112
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0087 0.006 0.5902
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0085 0.0058 0.5
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Echinococcus granulosus tyrosine kinase 0.0073 0.0044 0.0038
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0517 0.0552 0.2972
Loa Loa (eye worm) hypothetical protein 0.014 0.012 0.0115
Leishmania major hypothetical protein, conserved 0.0052 0.002 0.0495
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0052 0.002 0.8067
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Toxoplasma gondii type I fatty acid synthase, putative 0.0087 0.006 0.3486
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Toxoplasma gondii subtilisin SUB5 0.0114 0.0091 0.5626
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Echinococcus granulosus fibrillin 2 0.017 0.0155 0.0188
Loa Loa (eye worm) TKL/MLK/LZK protein kinase 0.3204 0.3621 0.3618
Loa Loa (eye worm) hypothetical protein 0.0114 0.0091 0.0086
Brugia malayi ADAMTS-like protease 0.016 0.0144 0.0138
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.0015
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0114 0.0091 0.0101
Echinococcus multilocularis transfer RNA-Thr 0.0052 0.002 0.0005
Loa Loa (eye worm) hypothetical protein 0.1049 0.1159 0.1155
Entamoeba histolytica cysteine surface protein, putative 0.0052 0.002 0.8067
Schistosoma mansoni nuclear receptor nhr-48 0.0057 0.0026 0.0044
Echinococcus granulosus retinal guanylyl cyclase 2 0.0052 0.002 0.0005
Entamoeba histolytica receptor protein kinase, putative 0.0052 0.002 0.8067
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0052 0.002 0.0005
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0114 0.0091 0.0086
Loa Loa (eye worm) fatty acid synthase 0.0084 0.0056 0.0051
Brugia malayi Subtilase family protein 0.0114 0.0091 0.0086
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Toxoplasma gondii STE kinase 0.0052 0.002 0.0713
Echinococcus multilocularis tyrosine protein kinase pr2 0.0052 0.002 0.0005
Brugia malayi orphan nuclear receptor NR2E1 0.0057 0.0026 0.002
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Giardia lamblia Tenascin precursor 0.017 0.0155 0.1282
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0055 0.0024 0.001
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0124 0.0102 1
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0052 0.002 0.0015
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0052 0.002 0.0005
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0052 0.002 0.0005
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Schistosoma mansoni integrin alpha-ps 0.0114 0.0091 0.0156
Loa Loa (eye worm) hypothetical protein 0.017 0.0155 0.015
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0073 0.0044 0.0153
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.012 0.0098 0.0169
Echinococcus granulosus receptor type guanylyl cyclase 0.0073 0.0044 0.0038
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0053 0.0021 0.0006
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0114 0.0091 0.8656
Echinococcus multilocularis nuclear receptor nhr 48 0.0057 0.0026 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-14 0.012 0.0098 0.0093
Toxoplasma gondii hypothetical protein 0.017 0.0155 1
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.002 0.0021
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Schistosoma mansoni RAR-like nuclear receptor 0.012 0.0098 0.0169
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0114 0.0091 0.8939
Loa Loa (eye worm) TK protein kinase 0.0052 0.002 0.0015
Brugia malayi neuroendocrine convertase 1 precursor 0.1681 0.1881 0.1876
Loa Loa (eye worm) SRC-1 0.0052 0.002 0.0015
Toxoplasma gondii subtilisin SUB4 0.0114 0.0091 0.5626
Schistosoma mansoni protein kinase 0.0052 0.002 0.0034
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0057 0.0026 0.0044
Entamoeba histolytica serine/threonine kinase, putative 0.0052 0.002 0.8067
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.012 0.0098 0.0093
Loa Loa (eye worm) hypothetical protein 0.0057 0.0026 0.002
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0279 0.028 0.0359
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0052 0.002 0.0005
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0052 0.002 0.0034
Giardia lamblia High cysteine membrane protein Group 2 0.0994 0.1096 1
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0091 0.0416
Entamoeba histolytica hypothetical protein 0.0052 0.002 0.8067
Brugia malayi hypothetical protein 0.0057 0.0026 0.002
Toxoplasma gondii subtilisin SUB1 0.0114 0.0091 0.5626
Schistosoma mansoni hypothetical protein 0.006 0.003 0.0051
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0052 0.002 0.0005
Loa Loa (eye worm) hypothetical protein 0.012 0.0098 0.0093
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.012 0.0098 0.0169
Loa Loa (eye worm) serine/threonine protein kinase 0.0052 0.002 0.0015
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0057 0.0026 0.0035
Giardia lamblia Furin precursor putative serine protease 0.0517 0.0552 0.4959
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.012 0.0098 0.0112
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.002 0.8067
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.0076 0.007
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0109 0.0085 0.0146
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0052 0.002 0.0005
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0054 0.0023 0.0009
Schistosoma mansoni glutamate receptor NMDA 0.0279 0.028 0.048
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.002 0.0005
Entamoeba histolytica ankyrin repeat protein 0.0052 0.002 0.8067
Echinococcus granulosus integrin alpha ps 0.0105 0.0081 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.3255 0.368 0.6325
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.0015
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0052 0.002 0.0021
Plasmodium falciparum subtilisin-like protease 1 0.0114 0.0091 1
Brugia malayi Reprolysin 0.016 0.0144 0.0138
Loa Loa (eye worm) glutamate receptor 0.0063 0.0032 0.0027
Echinococcus multilocularis neuroendocrine convertase 2 0.1681 0.1881 0.2538
Loa Loa (eye worm) nuclear receptor NHR-67 0.0057 0.0026 0.002
Echinococcus multilocularis integrin alpha ps 0.0105 0.0081 0.0088
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Echinococcus granulosus retinoic acid receptor rxr beta a 0.087 0.0955 0.1277
Leishmania major protein kinase, putative 0.0052 0.002 0.0495
Brugia malayi EGF-like domain containing protein 0.017 0.0155 0.0149
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.012 0.0098 0.0093
Echinococcus multilocularis fibrillin 2 0.017 0.0155 0.0188
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.012 0.0098 0.0093
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Loa Loa (eye worm) endoprotease bli-4 0.2675 0.3017 0.3013
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.1625 0.1818 0.2452
Echinococcus multilocularis tyrosine protein kinase 0.0052 0.002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0057 0.0026 0.002
Brugia malayi Nuclear hormone receptor family member nhr-41 0.012 0.0098 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Echinococcus granulosus tyrosine protein kinase csk 0.0052 0.002 0.0005
Loa Loa (eye worm) kelch domain-containing protein family protein 0.1364 0.1519 0.1514
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Brugia malayi Tyrosine-protein kinase abl-1 0.0052 0.002 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0517 0.0552 0.2972
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.002 0.8067
Echinococcus granulosus epidermal growth factor receptor 0.0052 0.002 0.0005
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0274 0.0274 0.047
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.006 0.003 0.0018
Loa Loa (eye worm) hypothetical protein 0.0064 0.0034 0.0028
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0057 0.0026 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.002 0.0021
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0114 0.0091 0.8656
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.002 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0517 0.0552 0.2972
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Onchocerca volvulus Bile acid receptor homolog 0.012 0.0098 0.0494
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.017 0.0155 0.0769
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Entamoeba histolytica tyrosin kinase, putative 0.0052 0.002 0.8067
Echinococcus granulosus Furin 1 0.0632 0.0682 0.0907
Echinococcus multilocularis FTZ F1 alpha 0.012 0.0098 0.0112
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0052 0.002 0.0005
Brugia malayi bone morphogenetic protein type 1 receptor 0.0052 0.002 0.0015
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Schistosoma mansoni ADAMTS14 peptidase (M12 family) 0.0076 0.0047 0.0081
Echinococcus granulosus fibroblast growth factor receptor 4 0.0052 0.002 0.0005
Echinococcus granulosus Nuclear hormone receptor HR96 0.0057 0.0026 0.0013
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.002 0.0005
Schistosoma mansoni nuclear receptor 0.0057 0.0026 0.0044
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0082 0.0054 0.4065
Echinococcus multilocularis receptor type guanylyl cyclase 0.0073 0.0044 0.0038
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Echinococcus granulosus glutamate receptor 2 0.0054 0.0023 0.0009
Entamoeba histolytica hypothetical protein 0.0052 0.002 0.8067
Loa Loa (eye worm) TK/EGFR protein kinase 0.0052 0.002 0.0015
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Schistosoma mansoni nuclear hormone receptor 0.012 0.0098 0.0169
Entamoeba histolytica hypothetical protein 0.0052 0.002 0.8067
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Brugia malayi Nuclear hormone receptor family member nhr-3 0.012 0.0098 0.0093
Giardia lamblia Neurogenic locus notch-like protein 0.017 0.0155 0.1282
Echinococcus granulosus tyrosine protein kinase Fyn 0.0052 0.002 0.0005
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Brugia malayi Protein kinase domain containing protein 0.0069 0.004 0.0034
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0052 0.002 0.0713
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Brugia malayi SRC-1 0.0052 0.002 0.0015
Trichomonas vaginalis protein kinase atn1, putative 0.0052 0.002 0.0021
Giardia lamblia hypothetical protein 0.017 0.0155 0.1282
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.1441 0.1607 1
Brugia malayi ube2i2 protein 0.0049 0.0016 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-25 0.012 0.0098 0.0093
Schistosoma mansoni nuclear hormone receptor 0.0057 0.0026 0.0044
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0064 0.0034 0.0028
Echinococcus granulosus tyrosine protein kinase Fyn 0.0052 0.002 0.0005
Echinococcus multilocularis membrane bound transcription factor site 1 0.0114 0.0091 0.0102
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Brugia malayi hypothetical protein 0.0052 0.002 0.0015
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Brugia malayi hypothetical protein 0.1353 0.1507 0.1502
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Mycobacterium ulcerans thioesterase 0.0071 0.0042 0.2482
Echinococcus granulosus tyrosine protein kinase shark 0.0052 0.002 0.0005
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0052 0.002 0.0005
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0052 0.002 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Loa Loa (eye worm) RGC/RGC protein kinase 0.0052 0.002 0.0015
Brugia malayi nuclear hormone receptor 0.012 0.0098 0.0093
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0049 0.0016 0.0457
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0054 0.0023 0.0009
Loa Loa (eye worm) hypothetical protein 0.0098 0.0073 0.0068
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Brugia malayi angiogenesis inhibito 0.016 0.0144 0.0138
Loa Loa (eye worm) integrin alpha pat-2 0.0754 0.0822 0.0817
Brugia malayi Nuclear hormone receptor family member nhr-31 0.012 0.0098 0.0093
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0052 0.002 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0517 0.0552 0.2972
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0064 0.0034 0.0057
Brugia malayi Nuclear hormone receptor-like 1 0.0064 0.0034 0.0028
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0052 0.002 0.0005
Echinococcus multilocularis fibrillin 1 0.0183 0.017 0.0209
Onchocerca volvulus 0.0073 0.0044 0.0153
Loa Loa (eye worm) subtilase 0.0114 0.0091 0.0086
Brugia malayi conserved hypotetical protein 0.0057 0.0026 0.002
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Brugia malayi nuclear receptor NHR-88 0.012 0.0098 0.0093
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Loa Loa (eye worm) hypothetical protein 0.0114 0.0091 0.0086
Loa Loa (eye worm) TK protein kinase 0.0052 0.002 0.0015
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0052 0.002 0.8067
Echinococcus multilocularis FL cytokine receptor 0.0052 0.002 0.0005
Echinococcus granulosus tyrosine protein kinase Fyn 0.0052 0.002 0.0005
Onchocerca volvulus 0.0087 0.006 0.0254
Schistosoma mansoni integrin beta subunit 0.5126 0.5817 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0052 0.002 0.0005
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0079 0.0051 0.5021
Entamoeba histolytica hypothetical protein 0.0052 0.002 0.8067
Schistosoma mansoni integrin alpha-ps 0.0219 0.0211 0.0363
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0065 0.0035 0.172
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0114 0.0091 0.86
Entamoeba histolytica hypothetical protein 0.0052 0.002 0.8067
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.002 0.0034
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0105 0.0081 0.0076
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Echinococcus granulosus metabotropic glutamate receptor 5 0.0073 0.0044 0.0038
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Schistosoma mansoni protein kinase 0.0073 0.0044 0.0076
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0125 0.0104 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0052 0.002 0.0005
Schistosoma mansoni ephrin receptor 0.0052 0.002 0.0034
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Echinococcus multilocularis heat shock protein 70 0.0052 0.002 0.0005
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.012 0.0098 0.0112
Echinococcus granulosus protein kinase 0.0052 0.002 0.0005
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0064 0.0034 0.0023
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0341 0.035 0.0454
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0052 0.002 0.8067
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.0015
Schistosoma mansoni ubiquitin-conjugating enzyme E2 I 0.0049 0.0016 0.0028
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0632 0.0682 0.3697
Loa Loa (eye worm) RGC/RGC protein kinase 0.0073 0.0044 0.0039
Loa Loa (eye worm) hypothetical protein 0.0064 0.0034 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0052 0.002 0.0005
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1625 0.1818 1
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0082 0.0054 0.4065
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0124 0.0102 1
Echinococcus multilocularis tyrosine protein kinase Abl 0.0052 0.002 0.0005
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0057 0.0026 0.0013
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Loa Loa (eye worm) hypothetical protein 0.0076 0.0047 0.0042
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0114 0.0091 0.0157
Onchocerca volvulus 0.007 0.0041 0.013
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0065 0.0035 0.172
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.012 0.0098 0.0112
Schistosoma mansoni tyrosine protein kinase 0.0052 0.002 0.0034
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.006 0.003 0.0051
Echinococcus granulosus metabotropic glutamate receptor 2 0.0055 0.0024 0.001
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.006 0.003 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0052 0.002 0.0034
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0073 0.0044 0.0038
Giardia lamblia Tenascin-X 0.017 0.0155 0.1282
Echinococcus granulosus integrin alpha 3 0.0375 0.0389 0.0507
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Entamoeba histolytica serine/threonine kinase, putative 0.0052 0.002 0.8067
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.002 0.8067
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Trichomonas vaginalis protein tyrosine kinase, putative 0.0052 0.002 0.0021
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0082 0.0055 0.5353
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.2675 0.3017 0.5185
Echinococcus granulosus fibrillin 1 0.017 0.0155 0.0188
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Echinococcus granulosus tyrosine protein kinase Blk 0.0052 0.002 0.0005
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Schistosoma mansoni retinoid-x-receptor (RXR) 0.012 0.0098 0.0169
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0057 0.0026 0.002
Brugia malayi protein-tyrosine kinase 0.0052 0.002 0.0015
Giardia lamblia Kinase, NEK 0.0052 0.002 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0073 0.0044 0.0039
Echinococcus granulosus tyrosine kinase 0.0052 0.002 0.0005
Brugia malayi Integrin alpha cytoplasmic region family protein 0.037 0.0383 0.0378
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.0015
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Schistosoma mansoni hypothetical protein 0.006 0.003 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0517 0.0552 0.2972
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.012 0.0098 0.0112
Loa Loa (eye worm) TK/DDR protein kinase 0.0052 0.002 0.0015
Toxoplasma gondii subtilisin SUB2 0.0114 0.0091 0.5626
Brugia malayi nuclear hormone receptor family member nhr-6 0.0057 0.0026 0.002
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0064 0.0034 0.0057
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0052 0.002 0.0015
Schistosoma mansoni hypothetical protein 0.0052 0.002 0.0034
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0133 0.0113 0.0132
Brugia malayi photoreceptor-specific nuclear receptor 0.012 0.0098 0.0093
Loa Loa (eye worm) DR-78 0.0057 0.0026 0.002
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Echinococcus granulosus natriuretic peptide receptor 1 0.0052 0.002 0.0005
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0054 0.0023 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Loa Loa (eye worm) hypothetical protein 0.012 0.0098 0.0093
Echinococcus multilocularis tyrosine kinase 0.0073 0.0044 0.0038
Entamoeba histolytica serine/threonine kinase, putative 0.0052 0.002 0.8067
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0057 0.0026 0.0044
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0133 0.0113 0.0132
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Giardia lamblia Neurogenic locus Notch protein precursor 0.017 0.0155 0.1282
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Loa Loa (eye worm) hypothetical protein 0.0064 0.0034 0.0028
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Entamoeba histolytica serine/threonine kinase, putative 0.0052 0.002 0.8067
Brugia malayi tailless protein 0.0057 0.0026 0.002
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.002 0.8067
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.002 0.8067
Echinococcus granulosus ecdysone induced protein 78C 0.012 0.0098 0.0112
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0052 0.002 0.0005
Entamoeba histolytica receptor protein kinase, putative 0.0052 0.002 0.8067
Brugia malayi Raf kinase 0.0052 0.002 0.0015
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Mycobacterium tuberculosis Probable thioesterase TesA 0.0071 0.0042 0.4064
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Loa Loa (eye worm) TK/Met protein kinase 0.0052 0.002 0.0015
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0409 0.0429 0.0423
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0052 0.002 0.0034
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0341 0.035 0.0454
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0517 0.0552 0.2972
Brugia malayi nuclear hormone receptor family member odr-7 0.0057 0.0026 0.002
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0052 0.002 0.0034
Echinococcus granulosus adam 0.0528 0.0564 0.0746
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Echinococcus granulosus tyrosine protein kinase Lyn 0.0053 0.0021 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.002 0.0021
Echinococcus granulosus tyrosine protein kinase Src64B 0.0052 0.002 0.0005
Loa Loa (eye worm) hypothetical protein 0.012 0.0098 0.0093
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0052 0.002 0.0005
Echinococcus granulosus activin receptor type 0.0053 0.0021 0.0006
Loa Loa (eye worm) hypothetical protein 0.0114 0.0091 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.002 0.0034
Loa Loa (eye worm) hypothetical protein 0.0069 0.0039 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-19 0.012 0.0098 0.0093
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0052 0.002 0.0005
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0757 0.0825 0.1101
Trichomonas vaginalis hypothetical protein 0.017 0.0155 0.0769
Schistosoma mansoni metabotropic glutamate receptor 0.0039 0.0006 0.0009
Brugia malayi hypothetical protein 0.0057 0.0026 0.002
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0055 0.0024 0.0957
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0087 0.006 0.5902
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Brugia malayi ephrin receptor 1 precursor 0.0052 0.002 0.0015
Trichomonas vaginalis TK family protein kinase 0.0052 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.012 0.0098 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.002 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Brugia malayi AMP-binding enzyme family protein 0.0079 0.0051 0.0046
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Echinococcus granulosus retinal guanylyl cyclase 2 0.0052 0.002 0.0005
Echinococcus multilocularis tyrosine kinase 0.0052 0.002 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0091 0.0416
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.012 0.0098 0.0093
Echinococcus multilocularis protein tyrosine kinase 0.0052 0.002 0.0005
Echinococcus granulosus insulin receptor 0.0052 0.002 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0409 0.0429 0.0423
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0274 0.0274 0.0269
Onchocerca volvulus 0.012 0.0098 0.0494
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0806 0.0882 0.1178
Trichomonas vaginalis AGC family protein kinase 0.0052 0.002 0.0021
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0632 0.0682 0.3697
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Plasmodium falciparum tyrosine kinase-like protein 0.0052 0.002 0.0495
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Echinococcus granulosus tyrosine protein kinase Srms 0.0052 0.002 0.0005
Schistosoma mansoni serine/threonine RGC 0.0052 0.002 0.0034
Leishmania major subtilisin-like serine peptidase 0.0114 0.0091 1
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Brugia malayi nuclear receptor NHR-67 0.0057 0.0026 0.002
Toxoplasma gondii subtilisin SUB10 0.0114 0.0091 0.5626
Brugia malayi Kelch motif family protein 0.1364 0.1519 0.1514
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.012 0.0098 0.0093
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0052 0.002 0.0005
Plasmodium vivax subtilisin-like protease 1 0.0114 0.0091 1
Loa Loa (eye worm) TK protein kinase 0.0052 0.002 0.0015
Brugia malayi EGF-like domain containing protein 0.017 0.0155 0.0149
Entamoeba histolytica hypothetical protein 0.0052 0.002 0.8067
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0061 0.003 0.2975
Onchocerca volvulus Protein ultraspiracle homolog 0.012 0.0098 0.0494
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0079 0.0051 0.0046
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Brugia malayi Stress-activated protein kinase jnk-1 0.0227 0.022 0.0215
Echinococcus granulosus adam 17 protease 0.0114 0.0091 0.0101
Mycobacterium ulcerans Type I modular polyketide synthase 0.0082 0.0054 0.4065
Echinococcus multilocularis integrin alpha 3 0.0375 0.0389 0.0507
Brugia malayi Disintegrin family protein 0.0114 0.0091 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-1 0.012 0.0098 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Loa Loa (eye worm) TK/INSR protein kinase 0.0052 0.002 0.0015
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0085 0.0058 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.022 0.0378
Echinococcus granulosus activated cdc42 kinase 1 0.0052 0.002 0.0005
Trypanosoma cruzi protein kinase, putative 0.0052 0.002 0.0426
Echinococcus granulosus thyroid hormone receptor alpha 0.0057 0.0026 0.0013
Loa Loa (eye worm) TK protein kinase 0.0052 0.002 0.0015
Echinococcus granulosus tyrosine protein kinase pr2 0.0052 0.002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0057 0.0026 0.002
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0057 0.0026 0.0013
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0052 0.002 0.0005
Echinococcus granulosus integrin alpha ps 0.0219 0.0211 0.0265
Echinococcus multilocularis adam 0.0528 0.0564 0.0746
Schistosoma mansoni protein kinase 0.0052 0.002 0.0034
Onchocerca volvulus 0.0098 0.0073 0.0333
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Echinococcus multilocularis thyroid hormone receptor alpha 0.012 0.0098 0.0112
Echinococcus multilocularis 0.2157 0.2425 0.3279
Echinococcus granulosus protein tyrosine kinase 0.0052 0.002 0.0005
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0052 0.002 0.0015
Entamoeba histolytica tyrosin kinase, putative 0.0052 0.002 0.8067
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.012 0.0098 0.0169
Schistosoma mansoni apoptosis regulator bax 0.006 0.003 0.0051
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0114 0.0091 0.0101
Onchocerca volvulus 0.0148 0.0129 0.0689
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0052 0.002 0.0005
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Toxoplasma gondii subtilisin SUB9 0.0114 0.0091 0.5626
Echinococcus multilocularis raf serine:threonine protein kinase 0.0052 0.002 0.0005
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0052 0.002 0.0005
Schistosoma mansoni tyrosine kinase 0.0052 0.002 0.0034
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0052 0.002 0.0015
Echinococcus granulosus retinal guanylyl cyclase 2 0.0052 0.002 0.0005
Schistosoma mansoni coup transcription factor 0.012 0.0098 0.0169
Loa Loa (eye worm) hypothetical protein 0.037 0.0383 0.0378
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Schistosoma mansoni integrin alpha 0.0489 0.0519 0.0892
Loa Loa (eye worm) hypothetical protein 0.0042 0.0009 0.0003
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0091 0.0416
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.002 0.8067
Schistosoma mansoni site-1 peptidase (S08 family) 0.0114 0.0091 0.0157
Echinococcus granulosus c-Jun N-terminal kinases 0.0227 0.022 0.0277
Brugia malayi ADAM-TS Spacer 1 family protein 0.016 0.0144 0.0138
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0054 0.0023 0.0009
Loa Loa (eye worm) hypothetical protein 0.3203 0.362 0.3617
Plasmodium vivax tyrosine kinase-like protein, putative 0.0052 0.002 0.0495
Echinococcus multilocularis disintegrin and metalloproteinase 0.0114 0.0091 0.0101
Schistosoma mansoni tyrosine kinase 0.0073 0.0044 0.0076
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0052 0.002 0.0015
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Schistosoma mansoni hypothetical protein 0.0517 0.0552 0.0948
Trypanosoma brucei subtilisin peptidase 0.0114 0.0091 0.86
Loa Loa (eye worm) TK protein kinase 0.0052 0.002 0.0015
Echinococcus granulosus neuroendocrine convertase 2 0.1681 0.1881 0.2538
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0053 0.0021 0.0774
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0114 0.0091 0.0102
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Schistosoma mansoni thyroid hormone receptor 0.012 0.0098 0.0169
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Echinococcus multilocularis activin receptor type 0.0053 0.0021 0.0006
Brugia malayi hypothetical protein 0.0052 0.002 0.0015
Schistosoma mansoni protein kinase 0.0052 0.002 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Trichomonas vaginalis conserved hypothetical protein 0.0517 0.0552 0.2972
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0125 0.0104 1
Leishmania major protein kinase, putative 0.0053 0.0021 0.0614
Brugia malayi Protein kinase domain containing protein 0.3204 0.3621 0.3618
Loa Loa (eye worm) hypothetical protein 0.0057 0.0026 0.002
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0064 0.0034 0.0028
Schistosoma mansoni furin-1 (S08 family) 0.1163 0.129 0.2217
Echinococcus granulosus tyrosine protein kinase HCK 0.0052 0.002 0.0005
Toxoplasma gondii subtilisin SUB7 0.0114 0.0091 0.5626
Brugia malayi Nuclear hormone receptor family member nhr-25 0.012 0.0098 0.0093
Schistosoma mansoni glutamate receptor NMDA 0.0054 0.0023 0.0039
Echinococcus multilocularis integrin alpha ps 0.0219 0.0211 0.0265
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0358 0.037 0.0636
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0057 0.0026 0.0013
Loa Loa (eye worm) proprotein convertase 2 0.0632 0.0682 0.0677
Trichomonas vaginalis conserved hypothetical protein 0.0517 0.0552 0.2972
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0091 0.0416
Loa Loa (eye worm) hypothetical protein 0.012 0.0098 0.0093
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0274 0.0274 0.035
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0052 0.002 0.0005
Schistosoma mansoni protein kinase 0.0053 0.0021 0.0036
Entamoeba histolytica hypothetical protein 0.0052 0.002 0.8067
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.012 0.0098 0.0112
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.002 0.0015
Brugia malayi ecdysteroid receptor 0.012 0.0098 0.0093
Echinococcus granulosus epidermal growth factor receptor 0.0052 0.002 0.0005
Brugia malayi endoprotease bli-4 precursor 0.2675 0.3017 0.3013
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0053 0.0021 0.0528
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Trichomonas vaginalis conserved hypothetical protein 0.0517 0.0552 0.2972
Echinococcus multilocularis protein jagged 2 0.017 0.0155 0.0188
Loa Loa (eye worm) hypothetical protein 0.0073 0.0044 0.0039
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Schistosoma mansoni site-1 peptidase (S08 family) 0.0114 0.0091 0.0157
Echinococcus multilocularis protein KINase family member (kin 25) 0.0052 0.002 0.0005
Plasmodium falciparum subtilisin-like protease 2 0.0114 0.0091 1
Echinococcus multilocularis nmda type glutamate receptor 0.0118 0.0096 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0517 0.0552 0.2972
Loa Loa (eye worm) hypothetical protein 0.0098 0.0073 0.0068
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0052 0.002 0.0005
Giardia lamblia Kinase, NEK 0.0052 0.002 0.0034
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0052 0.002 0.0015
Entamoeba histolytica hypothetical protein 0.0052 0.002 0.8067
Brugia malayi Integrin alpha pat-2 precursor 0.0489 0.0519 0.0514
Brugia malayi Furin-like cysteine rich region family protein 0.0052 0.002 0.0015
Brugia malayi Protein kinase domain containing protein 0.007 0.0041 0.0035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0057 0.0026 0.0013
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Brugia malayi Protein kinase domain containing protein 0.0052 0.002 0.0015
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0053 0.0021 0.0528
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.002 0.8067
Loa Loa (eye worm) hypothetical protein 0.016 0.0144 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0052 0.002 0.0021
Loa Loa (eye worm) TK protein kinase 0.0052 0.002 0.0015
Entamoeba histolytica protein kinase, putative 0.0052 0.002 0.8067
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0632 0.0682 0.3697
Echinococcus multilocularis ecdysone induced protein 78C 0.012 0.0098 0.0112
Brugia malayi hypothetical protein 0.0358 0.037 0.0365
Echinococcus granulosus furin 0.2675 0.3017 0.4084
Loa Loa (eye worm) reprolysin 0.0274 0.0274 0.0269
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0052 0.002 0.0015

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 0.041 uM Effective concentration of the compound against Wild Type HIV-1 virus in human peripheral blood mononuclear cells ChEMBL. 15189036
EC50 (functional) > 50 uM Effective concentration of the compound against M184V HIV-1 virus in human peripheral blood mononuclear cells ChEMBL. 15189036

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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